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https://www.readbyqxmd.com/read/27072989/a-head-to-head-evaluation-of-8-biochemical-scanning-tools-for-unmeasured-ions
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Thomas J Morgan, Chris M Anstey, Matthew B Wolf
We aimed to evaluate the sensitivity and specificity of 8 biochemical scanning tools in signalling the presence of unmeasured anions. We used blood gas and biochemical data from 15 patients during and after cardio-pulmonary bypass. Sampling time-points were pre-bypass (T1), 2 min post equilibration with priming fluid containing acetate and gluconate anions (T2), late bypass (T3) and 4 h after surgery (T4). We calculated the anion gap (AG), albumin-corrected anion gap (AGc), whole blood base excess (BE) gap, plasma BE gap, standard BE gap and the strong ion gap (SIG), plus 2 new indices-the unmeasured ion index (UIX) and unmeasured plasma anions according to the interstitial, plasma and erythrocyte acid-base model (IPEua)...
April 12, 2016: Journal of Clinical Monitoring and Computing
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