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https://www.readbyqxmd.com/read/28430633/association-between-coronary-heart-disease-and-erectile-dysfunction-in-chinese-han-population
#1
Guo-Xiang Tian, Sheng Li, Tong-Zu Liu, Xian-Tao Zeng, Wan-Lin Wei, Xing-Huan Wang
To investigate the association between coronary heart disease (CHD) and erectile dysfunction (ED) in Chinese Han population. Patients who went to the andrological out-patient clinic of our hospital between August 1, 2015 and May 1, 2016 and met all eligible criteria were enrolled in this study. The patients diagnosed as ED using self-administered International Index of Erectile Function-5 (IIEF-5) questionnaire were considered as case group and others were considered as control. The cases were categorized as mild, moderate, and severe ED...
February 23, 2017: Oncotarget
https://www.readbyqxmd.com/read/28430555/beyond-wires-and-seeds-reflector-guided-breast-lesion-localization-and-excision
#2
Victoria L Mango, Ralph T Wynn, Sheldon Feldman, Lauren Friedlander, Elise Desperito, Sejal N Patel, Ameer Gomberawalla, Richard Ha
Purpose To evaluate outcomes of Savi Scout (Cianna Medical, Aliso Viejo, Calif) reflector-guided localization and excision of breast lesions by analyzing reflector placement, localization, and removal, along with target excision and rates of repeat excision (referred to as re-excision). Materials and Methods A single-institution retrospective review of 100 women who underwent breast lesion localization and excision by using the Savi Scout surgical guidance system from June 2015 to May 2016 was performed. By using image guidance 0-8 days before surgery, 123 nonradioactive, infrared-activated, electromagnetic wave reflectors were percutaneously inserted adjacent to or within 111 breast targets...
April 21, 2017: Radiology
https://www.readbyqxmd.com/read/28429750/correlations-of-tnf-%C3%AE-gene-promoter-polymorphisms-with-the-risk-of-thymoma-associated-myasthenia-gravis-in-a-northern-chinese-han-population
#3
H-W Yang, P Lei, Y-C Xie, Z-L Han, D Li, S-H Wang, Z-L Sun
This study was performed with the aim to investigate the correlations of tumor necrosis factor-alpha (TNF-α) gene promoter polymorphisms with the risk of thymoma-associated myasthenia gravis (T-MG) in a northern Chinese Han population. Between June 2005 and June 2015, 305 MG patients (150 males and 155 females, MG group) and 293 healthy volunteers (negative control (NC) group) were enrolled in this study. Among the MG patients, there were 121 patients with thymoma-associated MG (T-MG group) and 184 without T-MG (NT-MG group)...
April 21, 2017: Cancer Gene Therapy
https://www.readbyqxmd.com/read/28426392/design-and-validation-of-a-new-method-to-detect-and-quantify-residual-host-cell-dna-in-human-recombinant-erythropoietin-repo
#4
Shima Zamanian, Samira Mohammadi-Yeganeh, Vahid Kia, Hooman Kaghazian, Mahdi Paryan
During the purification of Human Recombinant EPO (rEPO) from host cells, residual DNA may remain in final products. This contamination is a risk factor for patients and may result in the inactivation of some tumor suppressor genes (TSG) or activation of oncogenes if its concentration is more than the standard defined by WHO. Based on WHO's criteria, acceptable level of residual DNA in biopharmaceuticals is less than 10-100 picograms/dose. In this study we have designed a sensitive and specific Quantitative Real-time PCR assay for detection of residual DNA in human rEPO products...
April 20, 2017: Preparative Biochemistry & Biotechnology
https://www.readbyqxmd.com/read/28426357/a-qualitative-assessment-of-alcohol-consumption-and-sexual-risk-behaviors-among-men-who-have-sex-with-men-and-transgender-women-in-peru
#5
Panagiotis Vagenas, Shan-Estelle Brown, Jesse L Clark, Kelika A Konda, Javier R Lama, Jorge Sánchez, Ann C Duerr, Frederick L Altice
BACKGROUND: Peruvian men who have sex with men (MSM) and transgender women (TGW) experience the double burden of a highly concentrated HIV epidemic with a high prevalence of alcohol use disorders (AUDs). Recent research has associated both with risky sexual behaviors, including unprotected sex, having multiple sexual partners, engaging in sex work, having recent sexually transmitted infections, and having HIV-infected partners. AUDs have also been associated in MSM/TGW with being unaware of HIV+ status...
June 7, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28425348/integration-of-functional-mri-and-white-matter-tractography-in-cyberknife-radiosurgery
#6
Lu Sun, Baolin Qu, Jinyuan Wang, Zhongjian Ju, Zizhong Zhang, Zhiqiang Cui, Yang Jack, Zhipei Ling, Xinguang Yu, Longsheng Pan
PURPOSE: To investigate the efficacy of the integration of functional magnetic resonance imaging and diffusion-tensor imaging tractography data into CyberKnife radiosurgery for intracranial tumor management. MATERIALS AND METHODS: Functional neuroimaging, anatomical magnetic resonance imaging, and computed tomography images of patients with brain lesions in critical areas were acquired before radiosurgery. The acquired data sets were coregistered using the MIM image fusion software module and then were imported into the CyberKnife Robotic Radiosurgery System (Multiplan 4...
January 1, 2017: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/28425241/incidence-of-cancer-in-the-turkish-republic-of-northern-cyprus
#7
Ruqiya Pervaiz, Pınar Tulay, Faisal Faisal, Nedime Serakinci
BACKGROUND/AIM: This study analyzed the incidence, trends, and common types of cancer in the Turkish Republic of Northern Cyprus (TRNC). MATERIALS AND METHODS: This study is based on data collected from the office of the North Cyprus Cancer Registry, Ministry of Health, for 2007-2012. Data were arranged on the basis of age group, sex, and cancer site. Age standardized incidence rates (ASRs) were estimated with the world standard population. EVIEWS (version 9) software was used for statistical analysis...
April 18, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28424789/cognitive-behavioral-coping-illness-perception-and-family-adaptability-in-oncological-patients-with-a-family-history-of-cancer
#8
Roxana Postolica, Magdalena Iorga, Florin Dumitru Petrariu, Doina Azoicai
Aim. The study investigated the differences between patients with and without a family history of cancer regarding coping strategies, illness perception, and family adaptability to the disease. Material and Methods. A total of 124 patients diagnosed with cancer were included in the research (55 of them with a family history of cancer). The Cognitive Emotion Regulation Questionnaire, the Strategic Approach to Coping Scale, the Family Adaptability and Cohesion Scale, and the Illness Perception Questionnaire were applied...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28423490/reappraisal-of-xrcc1-arg194trp-polymorphism-and-glioma-risk-a-cumulative-meta-analysis
#9
Jun-Ti Lu, Ai-Ping Deng, Juan Song, Li Zhang, Jie Luo
The association between XRCC1 Arg194Trp polymorphism and glioma risk were inconsistent from published meta-analyses and epidemiological studies. Hence, we performed this updated and cumulative meta-analysis to reappraisal this relationship. PubMed, Embase, CBM (Chinese Biomedical Database), and CNKI (China National Knowledge Internet) databases were comprehensively searched up to August 13, 2016 (updated on December 22, 2016). After study selection and data extraction from eligible studies, the association was evaluated by odds ratios (ORs) and its 95% confidence intervals (95%CIs) using Comprehensive Meta-Analysis software...
March 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28423026/the-relationship-between-diabetes-and-colorectal-cancer-prognosis-a-meta-analysis-based-on-the-cohort-studies
#10
Bo Zhu, Xiaomei Wu, Bo Wu, Dan Pei, Lu Zhang, Lixuan Wei
INTRODUCTION: Though a meta-analysis reported the effect of diabetes on colorectal prognosis in 2013, a series of large-scale long-term cohort studies has comprehensively reported the outcome effect estimates on the relationship between diabetes and colorectal prognosis, and their results were still consistent. METHODS: We carried out an extensive search strategy in multiple databases and conducted a meta-analysis on the effect of diabetes on colorectal prognosis, based on the included 36 cohort studies, which contained 2,299,012 subjects...
2017: PloS One
https://www.readbyqxmd.com/read/28423003/hacdivsel-two-new-methods-haplotype-based-and-outlier-based-for-the-detection-of-divergent-selection-in-pairs-of-populations
#11
Antonio Carvajal-Rodríguez
The detection of genomic regions involved in local adaptation is an important topic in current population genetics. There are several detection strategies available depending on the kind of genetic and demographic information at hand. A common drawback is the high risk of false positives. In this study we introduce two complementary methods for the detection of divergent selection from populations connected by migration. Both methods have been developed with the aim of being robust to false positives. The first method combines haplotype information with inter-population differentiation (FST)...
2017: PloS One
https://www.readbyqxmd.com/read/28422709/preterm-birth-among-women-living-within-600-meters-of-high-voltage-overhead-power-lines-a-case-control-study
#12
Taktom Sadeghi, Amirmasoud Ahmadi, Maryam Javadian, Sayyed Asghar Gholamian, Mouloud Agajani Delavar, Sedigheh Esmailzadeh, Bahare Ahmadi, Mozhgan Sadat Hassanpour Hadighi
AIM: The issue of preterm birth due to exposure to magnetic fields from power lines is unclear. Exposure to electromagnetic field in uterus has been hypothesized as possible preterm birth. The aim of the present study was to determine whether living closer to high voltage power lines increased the risk of preterm labor. METHODS: In a nested case-control study, 135 cases of singleton live spontaneous preterm birth in Rohani hospital, Babol, Iran, during the period between 2013 and 2014 were studied...
April 18, 2017: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28422595/microleakage-of-sealants-after-phosphoric-acid-er-yag-laser-and-air-abrasion-enamel-conditioning-systematic-review-and-meta-analysis
#13
Ana Caroline Fumes, Daniele Lucca Longo, Andiara De Rossi, Tatiana Kelly da Silva Fidalgo, Francisco Wanderley Garcia de Paula E Silva, Maria Cristina Borsatto, Erika Calvano Küchler
PURPOSE: The aim of this systematic review and meta-analysis is to answer the focused question: Does the application of phosphoric acid, Er:YAG laser and air abrasion enamel conditioning methods previous to the oclusal sealant application in human permanent molars influence the microleakage? STUDY DESIGN: A literature research was carried out in the Pubmed Medline, Web of Science, Scopus and Cochrane databases using with the MeSH terms and keyword search strategy...
2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28421798/assessment-of-individual-carotenoid-and-vitamin-a-dietary-intake-in-overweight-and-obese-dominican-subjects
#14
Madeline Durán-Cabral, Irene Fernández-Jalao, Rocío Estévez-Santiago, Begoña Olmedilla Alonso
INTRODUCTION: Carotenoids are plant pigment with important biological activities in humans, such as provitamin-A among others. At present, there are no individual carotenoid intake data in the Dominican population, which is at risk of vitamin A deficiency and has an important percentage of overweight and obese individuals . OBJECTIVE: To assess the individual components of vitamin A intake (retinol, α-carotene, β-carotene and β-cryptoxanthin) and that of other relevant dietary carotenoids like lutein, zeaxanthin and lycopene of Dominican daily food intake...
March 30, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28421181/mct1-in-invasive-ductal-carcinoma-monocarboxylate-metabolism-and-aggressive-breast-cancer
#15
Jennifer M Johnson, Paolo Cotzia, Roberto Fratamico, Lekha Mikkilineni, Jason Chen, Daniele Colombo, Mehri Mollaee, Diana Whitaker-Menezes, Marina Domingo-Vidal, Zhao Lin, Tingting Zhan, Madalina Tuluc, Juan Palazzo, Ruth C Birbe, Ubaldo E Martinez-Outschoorn
Introduction: Monocarboxylate transporter 1 (MCT1) is an importer of monocarboxylates such as lactate and pyruvate and a marker of mitochondrial metabolism. MCT1 is highly expressed in a subgroup of cancer cells to allow for catabolite uptake from the tumor microenvironment to support mitochondrial metabolism. We studied the protein expression of MCT1 in a broad group of breast invasive ductal carcinoma specimens to determine its association with breast cancer subtypes and outcomes. Methods: MCT1 expression was evaluated by immunohistochemistry on tissue micro-arrays (TMA) obtained through our tumor bank...
2017: Frontiers in Cell and Developmental Biology
https://www.readbyqxmd.com/read/28419893/carbon-monoxide-related-fatalities-a-60-year-single-institution-experience
#16
Martin Janík, Michaela Ublová, Štepánka Kučerová, Petr Hejna
OBJECTIVE: Though carbon monoxide (CO) poisonings account currently for a relatively small percentage of total non-natural deaths in Europe, they represent a serious public health burden and significant component of avoidable mortality in many countries. Our aim was to investigate long-term trends and to determine epidemiologic characteristics of the CO-related deaths in the Czech Republic, recorded at the Department of Forensic Medicine in Hradec Králové. METHODS: This was an autopsy-based single-centre retrospective cohort study of all fatalities caused by CO poisoning over six decades (1947-2006)...
April 13, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28419023/interrelations-of-epicardial-fat-volume-left-ventricular-t1-relaxation-times-and-myocardial-strain-in-hypertensive-patients-a-cardiac-magnetic-resonance-study
#17
Rami Homsi, Daniel Kuetting, Alois Sprinkart, Nina Steinfeld, Michael Meier-Schroers, Julian Luetkens, Jennifer Nadal, Darius Dabir, Stefan Fischer, Juergen Gieseke, Hans Schild, Daniel Thomas
PURPOSE: This cardiac magnetic resonance study was performed to assess myocardial fibrosis by evaluating T1-relaxation time (T1), to measure left ventricular (LV) strain, and to determine epicardial fat volume (EFV) in hypertensive patients with no history of cardiovascular (CV) events and to relate the results to the presence of coronary atherosclerotic artery disease (CAD) in these patients. MATERIALS AND METHODS: A total of 123 subjects were examined at 1.5 T...
May 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/28418990/bone-density-microarchitecture-and-tissue-quality-following-long-term-treatment-with-tenofovir-emtricitabine-or-abacavir-lamivudine
#18
Robert Güerri-Fernández, Daniel Molina-Morant, Judit Villar-García, Sabina Herrera, Alicia González-Mena, Ana Guelar, Marta Trenchs-Rodríguez, Adolfo Díez-Pérez, Hernando Knobel
OBJECTIVES: HIV infection has been associated with reduced bone mineral density (BMD). Antiretroviral therapy has a deleterious effect on BMD, but its effect on bone fragility is not clear. The objective of this study is to analyze the BMD, microarchitecture and tissue quality of bone in patients receiving long-term tenofovir- or abacavir-based antiretroviral therapy. DESIGN: We conducted a cross-sectional study in HIV patients undergoing tenofovir or abacavir antiretroviral therapy for more than five years...
April 7, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28418854/association-between-the-brca2-rs144848-polymorphism-and-cancer-susceptibility-a-meta-analysis
#19
REVIEW
Qiuyan Li, Rongwei Guan, Yuandong Qiao, Chang Liu, Ning He, Xuelong Zhang, Xueyuan Jia, Haiming Sun, Jingcui Yu, Lidan Xu
The BRCA2 gene plays an important role in cancer carcinogenesis, and polymorphisms in this gene have been associated with cancer risk. The BRCA2 rs144848 polymorphism has been associated with several cancers, but results have been inconsistent. In the present study, a meta-analysis was performed to assess the association between the rs144848 polymorphism and cancer risk. Literature was searched from the databases of PubMed, Embase and Google Scholar before April 2016. The fixed or random effects model was used to calculate pooled odd ratios on the basis of heterogeneity...
March 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28415947/effect-of-pretreatment-with-midazolam-on-etomidate-induced-myoclonus-a-meta-analysis
#20
Chengmao Zhou, Yu Zhu, Zhen Liu, Lin Ruan
Objective To investigate the effect of pretreatment with midazolam on myoclonus induced by etomidate injection. Methods A meta-analysis was performed using Review Manager software, version 5.2. Two researchers independently searched PubMed, Cochrane Library, and Embase® databases for randomized controlled trials involving patients who underwent etomidate induced general anaesthesia with or without midazolam pretreatment, published between 1990 and 2016. Outcome measures comprised overall myoclonus incidence rate and incidence rate classified by degree of myoclonus following etomidate injection...
April 2017: Journal of International Medical Research
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