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https://www.readbyqxmd.com/read/29166757/hybrid-imaging-of-musculoskeletal-infections
#1
Andor W Glaudemans, Napoleone Prandini, Marco DI Girolamo, Giuseppe Argento, Chiara Lauri, Elena Lazzeri, Mario Muto, Luca M Sconfienza, Alberto Signore
This review article highlights the role of radiological and nuclear medicine techniques in diagnosis of musculoskeletal infections with particular regard to hybrid imaging of osteomyelitis, prosthetic joint infections, sternal infections and spine infections. Authors conclude on the complementary role of the several techniques with indications for an appropriate diagnostic flow chart, in the light of the recent EANM guidelines on infection.
November 22, 2017: Quarterly Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29166553/botulinum-toxin-injection-versus-topical-nitrates-for-chronic-anal-fissure-an-updated-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#2
REVIEW
Shaheel M Sahebally, Babak Meshkat, Stewart R Walsh, David Beddy
BACKGROUND: Chronic anal fissures (CAF) are frequently encountered in coloproctology clinics. Chemical sphincterotomy with pharmacological agents is recommended as first-line therapy. Topical nitrates (TN) heal CAF effectively but recurrences are common. An alternative treatment modality is injection of botulinum toxin (BT) into the anal sphincter. We aimed to perform an updated systematic review and meta-analysis to compare the effectiveness of BT and TN in the management of CAF. METHODS: PubMed, EMBASE and Cochrane databases were searched for relevant articles from inception until March 2017...
November 22, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29166508/algorithm-for-acne-treatment-ibero-latin-american-consensus
#3
Ediléia Bagatin, Mercedes Florez-White, María Isabel Arias-Gomez, Ana Kaminsky
Acne is a chronic, immune-mediated, inflammatory disease with high prevalence among adolescents. By compromising face, thorax and back, with the risk of permanent scars, it has a negative impact on the quality of life. Effective, safe and early treatment is the key to remission, while decreasing the risk of physical and/or emotional sequelae. The Iberian-Latin American Group of Acne Studies joined professionals with expertise and developed a practical therapeutic algorithm, adapted to the reality of Latin American countries, Spain and Portugal...
September 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29166490/-guidelines-for-a-line-of-care-for-children-and-adolescents-with-complex-chronic-health-conditions
#4
Martha Cristina Nunes Moreira, Lidianne Vianna Albernaz, Miriam Ribeiro Calheiros de Sá, Roberta Fernandes Correia, Roberta Falcão Tanabe
The definition of complex chronic health condition (CCHC) is important for identifying children and adolescents occupying pediatric beds in Brazilian hospitals, where they live out their childhood, requiring complex care by multidisciplinary teams in network format both in-hospital and in home care. The current article addresses guidelines for a line of care for children and adolescents with CCHCs. An expert panel validated 13 guidelines organized in three dimensions. Using the consensus conference technique, experts from different specialties validated the guidelines...
November 21, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/29166440/maternal-complications-and-cesarean-section-without-indication-systematic-review-and-meta-analysis
#5
Keila Cristina Mascarello, Bernardo Lessa Horta, Mariângela Freitas Silveira
OBJECTIVE: The objective of this study was to determine the risks of severe acute maternal complications associated with cesarean section without medical indication. METHODS: A systematic review was carried out with meta-analysis. The literature search was performed systematically, in multiple stages, in the PubMed, Lilacs, and Web of Science databases using the following descriptors: (postpartum period) and (cesarean section or natural childbirth) and ((morbidity or mortality) or (postpartum hemorrhage) or (puerperal infection) or (surgical infection) or (puerperal disorders))...
2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29166352/more-learners-finite-resources-and-the-changing-landscape-of-procedural-training-at-the-bedside
#6
Michael A Gisondi, Linda Regan, Jeremy Branzetti, Laura R Hopson
There is growing competition for non-operative, procedural training in teaching hospitals, due to an increased number of individuals seeking to learn procedures from a finite number of appropriate teaching cases. Procedural training is required by students, post-graduate learners, and practicing providers who must maintain their skills. These learner groups are growing in size as the number of medical schools increase and advance practice providers expand their skills to include complex procedures. These various learner needs occur against a background of advancing therapeutic techniques that improve patient care, but also act to reduce the overall numbers of procedures available to learners...
November 21, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29166343/prepectoral-breast-reconstruction-in-challenging-patients
#7
Allen Gabriel, G Patrick Maxwell
Implant-based reconstructions continue to remain on the forefront of breast reconstruction as the prepectoral approach gains popularity. This article reviews the challenging patients that surgeons face when evaluating their candidacy for prepectoral reconstruction. The prepectoral approach for thin, high body mass index and previously radiated patients will be reviewed.
December 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29166297/assessing-patients-perceptions-of-safety-culture-in-the-hospital-setting-development-and-initial-evaluation-of-the-patients-perceptions-of-safety-culture-scale
#8
Clara Monaca, Beate Bestmann, Martina Kattein, Daria Langner, Hardy Müller, Tanja Manser
OBJECTIVES: Both, patient satisfaction and hospital safety culture have been recognized as key characteristics of healthcare quality and patient safety. Thus, both characteristics are measured widely to support quality and safety improvement efforts. However, because safety culture surveys focus exclusively on the perspective of hospital staff, the complimentary information to be gained from patients' perceptions of safety culture has received little research attention so far. We aimed to develop a measure explicitly focusing on patients' perceptions of safety culture in the hospital setting and perform an initial evaluation of its measurement properties...
November 21, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/29166246/imaging-features-of-gadoxetic-acid-enhanced-and-diffusion-weighted-mr-imaging-for-identifying-cytokeratin-19-positive-hepatocellular-carcinoma-a-retrospective-observational-study
#9
Seo-Youn Choi, Seong Hyun Kim, Cheol Keun Park, Ji Hye Min, Ji Eun Lee, Yoon-Hyeong Choi, Bo Ra Lee
Purpose To determine the preoperative magnetic resonance (MR) imaging findings potentially most useful for predicting cytokeratin 19 (CK19)-positive hepatocellular carcinoma (HCC) and to evaluate the prognosis after curative resection in patients with a single HCC lesion positive for CK19 compared with patients with HCC who are negative for CK19. Materials and Methods The institutional review board approved this study and waived the requirement for informed consent. Two hundred four patients with CK19-negative HCC and 38 with CK19-positive HCC who underwent curative resection after gadoxetic acid-enhanced and diffusion-weighted MR imaging were retrospectively evaluated in a single institution...
November 21, 2017: Radiology
https://www.readbyqxmd.com/read/29166245/evidence-supporting-li-rads-major-features-for-ct-and-mr-imaging-based-diagnosis-of-hepatocellular-carcinoma-a-systematic-review
#10
An Tang, Mustafa R Bashir, Michael T Corwin, Irene Cruite, Christoph F Dietrich, Richard K G Do, Eric C Ehman, Kathryn J Fowler, Hero K Hussain, Reena C Jha, Adib R Karam, Adrija Mamidipalli, Robert M Marks, Donald G Mitchell, Tara A Morgan, Michael A Ohliger, Amol Shah, Kim-Nhien Vu, Claude B Sirlin
The Liver Imaging Reporting and Data System (LI-RADS) standardizes the interpretation, reporting, and data collection for imaging examinations in patients at risk for hepatocellular carcinoma (HCC). It assigns category codes reflecting relative probability of HCC to imaging-detected liver observations based on major and ancillary imaging features. LI-RADS also includes imaging features suggesting malignancy other than HCC. Supported and endorsed by the American College of Radiology (ACR), the system has been developed by a committee of radiologists, hepatologists, pathologists, surgeons, lexicon experts, and ACR staff, with input from the American Association for the Study of Liver Diseases and the Organ Procurement Transplantation Network/United Network for Organ Sharing...
November 21, 2017: Radiology
https://www.readbyqxmd.com/read/29166217/the-radiologist-s-primer-to-imaging-the-noncuff-nonlabral-postoperative-shoulder
#11
Christopher R Smith, Jason T Yoon, Jeremiah R Long, Michael V Friedman, Travis J Hillen, James D Stensby
Many radiologists are familiar with the preoperative imaging assessment of patients with labral tears, rotator cuff abnormalities, and end-stage arthritis, as well as the subsequent primary reconstructions and repairs commonly encountered in routine clinical management. However, the second-line surgical procedures and augmentation procedures performed for refractory or recurrent shoulder instability and the extra-articular surgical procedures of the shoulder girdle may challenge even the most experienced musculoskeletal radiologist...
November 22, 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29166151/biomarkers-and-imaging-of-breast-cancer
#12
Olena Weaver, Jessica W T Leung
OBJECTIVE: The goals of this review are to provide background information on the definitions and applications of the general term "biomarker" and to highlight the specific roles of breast imaging biomarkers in research and clinical breast cancer care. A search was conducted of the main electronic biomedical databases (PubMed, Cochrane, Embase, MEDLINE [Ovid], Scopus, and Web of Science). The search was focused on review literature in general radiology and biomedical sciences and on reviews and primary research articles on biomarkers in breast imaging over the 15 years ending in June 2017...
November 22, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29165967/measurements-of-self-efficacy-in-patients-with-chronic-kidney-disease-a-literature-review
#13
Yu-Jie Guo, Qing Tang, Yu Gu
This article reviews the literature addressing assessment instruments about various aspects of self-efficacy in patients with chronic kidney disease (CKD). Each scale's structure, reliability, validity, and clinical application are described in detail. When selecting assessment tools to measure the self-efficacy level of patients with CKD, we should take the suitable subjects and application scope into account. With valid and reliable measurement tools, researchers and clinical nurses can assess and stimulate the self-efficacy of patients with CKD more effectively and carry out targeted nursing interventions so as to improve patients' self-efficacy level...
March 2017: Nephrology Nursing Journal: Journal of the American Nephrology Nurses' Association
https://www.readbyqxmd.com/read/29165905/loop-mediated-isothermal-amplification-lamp-a-versatile-technique-for-detection-of-microorganisms
#14
REVIEW
Yien-Ping Wong, Shuhaidah Othman, Yee-Ling Lau, Radu Son, Hui-Yee Chee
Loop mediated isothermal amplification (LAMP) amplifies DNA with high specificity, efficiency, and rapidity under isothermal conditions by using a DNA polymerase with high displacement strand activity and a set of specifically designed primers to amplify targeted DNA strands. Following its first discovery by Notomi et al. in the year 2000, LAMP was further developed over the years which involved the combination of this technique with other molecular approaches, such as reverse transcription and multiplex amplification for the detection of infectious diseases caused by microorganisms in humans, livestock and plants...
November 22, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29165892/assays-for-estimating-hiv-incidence-updated-global-market-assessment-and-estimated-economic-value
#15
Charles S Morrison, Rick Homan, Natasha Mack, Pairin Seepolmuang, Megan Averill, Jamilah Taylor, Jennifer Osborn, Peter Dailey, Neil Parkin, Stefano Ongarello, Timothy D Mastro
INTRODUCTION: Accurate incidence estimates are needed to characterize the HIV epidemic and guide prevention efforts. HIV Incidence assays are cost-effective laboratory assays that provide incidence estimates from cross-sectional surveys. We conducted a global market assessment of HIV incidence assays under three market scenarios and estimated the economic value of improved incidence assays. METHODS: We interviewed 27 stakeholders, and reviewed journal articles, working group proceedings, and manufacturers' sales figures...
November 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29165824/measurement-of-social-norms-affecting-modern-contraceptive-use-a-literature-review
#16
Elizabeth Costenbader, Rachel Lenzi, Rebecca B Hershow, Kim Ashburn, Donna R McCarraher
As a critical building block to developing social norms interventions to support healthy family planning and other reproductive health behaviors, we conducted a literature review to identify and evaluate social norm measures related to modern contraceptive use. Of 174 articles reviewed in full, only 17 studies met our criteria for inclusion. Across these articles, no single measure of norms was used in more than one study; failure to specify the boundaries of who was engaging in and influencing the behaviors of interest contributed to the variation...
November 22, 2017: Studies in Family Planning
https://www.readbyqxmd.com/read/29165795/therapeutic-potency-of-mtor-signaling-pharmacological-inhibitors-in-the-treatment-of-proinflammatory-diseases-current-status-and-perspectives
#17
REVIEW
Arash Soltani, Amirhossein Bahreyni, Nadia Boroumand, Mostafa Karimi Roshan, Majid Khazaei, Mikhail Ryzhikov, Saman Soleimanpour, Amir Avan, Seyed Mahdi Hassanian
Mammalian target of rapamycin (mTOR) signaling pathway controls cell energy metabolism. There is an interplay between mTOR and proinflammatory signaling pathways, supporting the role of the pathway in the pathogenesis of inflammatory diseases. Inhibition of mTOR signaling using specific pharmacological inhibitors could offer therapeutic promise in several inflammatory-associated diseases. In this review, we summarize recent findings on the regulatory effects of mTOR signaling on inflammation and the therapeutic potency of mTOR pharmacological inhibitors in the treatment of inflammatory diseases including cancer, neurodegenerative diseases, atherosclerosis, sepsis and rheumatoid arthritis for a better understanding and hence a better management of these diseases...
November 22, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29165774/hypospadias-in-male-infants-a-review
#18
X-Y Zhu, D-C Feng, T Han
The external genitalia problems are cumbersome problems for both doctors and parents, as these abnormalities have a consequent impact on future generations. However, the affected young infants are unaware of the consequences due to immature emotional state. Further, the feeling of being different and inferior in affected young patients could give rise to negative emotions including depression, insecurity, anxiety, powerlessness, etc. These all factors collectively could cause a mental imbalance in the affected children...
October 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29165772/pediatric-protein-metabolism-techniques-a-review
#19
G Liu, Z-G Li, H-W Wu
Some invasive techniques could be safely and ethically applied to estimate protein metabolism in children. Although these methodologies provide valuable information on whole body protein metabolism, a reflection of what is happening to thousands of protein molecules across a variety of different tissues. However, they provide little information regarding the contribution of specific tissues and proteins to the whole-body changes observed (e.g., whether the increase in protein synthesis was a result of the muscle or splanchnic tissues) which might otherwise be determined in more invasive procedures such as those with muscle biopsies...
October 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29165771/recent-perspectives-of-ependymomas-childhood-brain-tumors
#20
Z-D Zeng, F-L Liu, S-X Li
Ependymomas are childhood brain tumors that occur throughout the central nervous system, but are most common in the hindbrain, also known as the posterior fossa (PF). Current standard therapy comprises maximal safe surgery, and there is no scope for further increase in survival. Despite the histological similarity, ependymomas from throughout the neuroaxis likely comprise multiple independent entities, each with a distinct molecular pathogenesis. The present review article would discuss both genetics and epigenetics of ependymomas...
October 2017: European Review for Medical and Pharmacological Sciences
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