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https://www.readbyqxmd.com/read/28328267/dermatology-across-healthcare-settings
#1
Tracy Bale
A day in the life of Tracy Bale, Senior Nurse Dermatology, Rheumatology and Radiology, and Dermatology Clinical Nurse Specialist, Aneurin Bevan University Health Board, South Wales, who was awarded third place at the BJN Awards 2016 for Dermatology Nurse of the Year.
March 9, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28328159/improved-disease-activity-with-fosdagrocorat-pf-04171327-a-partial-agonist-of-the-glucocorticoid-receptor-in-patients-with-rheumatoid-arthritis-a-phase-2-randomized-study
#2
Thomas Stock, Dona Fleishaker, Xin Wang, Arnab Mukherjee, Charles Mebus
AIM: To assess efficacy and safety of fosdagrocorat (PF-04171327), a potential dissociated agonist of the glucocorticoid receptor, in rheumatoid arthritis (RA) patients. METHODS: This multicenter, double-blind, parallel-group, active- and placebo-controlled Phase 2 study (NCT00938587) randomized 86 patients (1 : 1 : 1 : 1) to receive fosdagrocorat 10 mg, fosdagrocorat 25 mg, prednisone 5 mg or placebo, all with stable background methotrexate therapy. The primary outcome was change from baseline in Disease Activity Score of 28 joints (DAS28-4[C-reactive protein (CRP)]) after 2 weeks of treatment...
March 22, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28327059/association-between-non-infectious-uveitis-and-thyroid-dysfunction-a-case-control-study
#3
Amir Rosenblatt, Hussein Zaitoon, Zohar Habot-Wilner
BACKGROUND: Several reports suggested a relation between uveitis and thyroid disease or dysfunction. However, no study has investigated the association between uveitis and thyroid dysfunction. The purpose of this study was to compare the prevalence of thyroid dysfunction in patients with and without non-infectious uveitis. METHODS: This was a retrospective, case-control study. RESULTS: Two hundred thirty-five non-infectious uveitis patients (uveitis group) and 600 controls (control group) were included in the study, of whom 492 (58...
March 22, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28327026/promoting-effective-teamwork-in-the-healthcare-setting
#4
Sarah Ryan
Patients require access to various healthcare professionals to manage their healthcare needs. Most nurses work in a team established to provide optimum care for patients. This article explores the stages necessary to develop an effective healthcare team and identifies the attributes required for effective teamwork. These include: effective leadership, a shared mental approach (a common understanding of the roles and responsibilities of all members of the team), respect among team members and shared training...
March 22, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28324149/-outpatient-care-and-disease-burden-of-rheumatoid-arthritis-results-of-a%C3%A2-linkage-of-claims-data-and-a%C3%A2-survey-of-insured-persons
#5
K Albrecht, A Luque Ramos, J Callhoff, F Hoffmann, K Minden, A Zink
BACKGROUND: Healthcare of patients with rheumatoid arthritis (RA) in Germany has mainly been evaluated in the past in RA cohorts from specialized arthritis centers. This study investigated rheumatological care on a population basis, using claims data from a nationwide statutory health insurance fund (BARMER GEK) in combination with patient-reported outcomes from a questionnaire survey of insured persons with RA. METHODS: Data from insurants aged 18-79 years with M05 (seropositive RA) or M06 (other RA, ICD-10) diagnoses were analyzed concerning diagnostics, medication and prescribing physician...
March 21, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28324148/comparative-efficacy-and-tolerability-of-sarilumab-150-and-200%C3%A2-mg-in-patients-with-active-rheumatoid-arthritis-a%C3%A2-bayesian-network-meta-analysis-of-randomized-controlled-trials
#6
S-C Bae, Y H Lee
OBJECTIVE: This study aimed to assess the relative efficacy and tolerability of every other week (q2w) dosing of sarilumab 150 and 200 mg in patients with active rheumatoid arthritis (RA). METHODS: In this network meta-analysis, randomized controlled trials (RCTs) examining the efficacy and tolerability of sarilumab in patients with active RA were included. A Bayesian network meta-analysis was conducted to combine the direct and indirect evidence from the RCTs...
March 21, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28324118/early-onset-polymyalgia-rheumatica-two-rare-cases-under-age-of-50
#7
Jinyoung Park, Duk Hyun Sung
Polymyalgia rheumatica (PMR) is almost an exclusive disease of adults over the age of 50, and only a few cases have been reported. Two 46-year-old females visited our locomotor pain clinic with multiple joint pain with increased acute phase reactants. Rheumatologic markers, and HLA-B27 were checked. Serum protein electrophoresis and serum immunofixation electrophoresis, imaging studies including plane image, sonography, and magnetic resonance image was done. (18)F-Fludeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) showed characteristic findings of PMR, without evidences of sacroiliitis...
March 21, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28323224/progressive-multifocal-leukoencephalopathy-and-rheumatoid-arthritis-treatments
#8
Gaëlle Clavel, Antoine Moulignier, Luca Semerano
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system due to reactivation of the JC virus (JCV). PML is extremely uncommon despite the high prevalence of the virus in the general population. No specific treatment is available, and the prognosis is bleak. The diagnosis is based on brain imaging findings, detection of the JCV genome in cerebrospinal fluid samples and, in some cases, histological studies of the brain lesions. The pathophysiological mechanisms that drive the development of PML are incompletely understood...
March 16, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28322805/modifying-the-trajectory-of-asthma-are-there-lessons-from-the-use-of-biologics-in-rheumatology
#9
J Mark FitzGerald, Paul Emery
No abstract text is available yet for this article.
March 18, 2017: Lancet
https://www.readbyqxmd.com/read/28322578/interview-with-amr-h-sawalha-epigenetics-and-autoimmunity
#10
Amr H Sawalha
Amr H Sawalha is Professor of Internal Medicine and Marvin and Betty Danto Research Professor of Connective Tissue Research at the University of Michigan, Department of Internal Medicine, Division of Rheumatology. He also holds faculty appointments at the Center for Computational Medicine and Bioinformatics and the Graduate Program in Immunology at the University of Michigan. He was recently appointed as Guest Professor at Central South University in Changsha, China. He received his medical degree from Jordan University of Science and Technology and completed his residency training in internal medicine at the University of Oklahoma Health Sciences Center, and his fellowship in rheumatology at the University of Michigan...
March 21, 2017: Epigenomics
https://www.readbyqxmd.com/read/28322172/immune-neuroendocrine-dysregulation-in-patients-with-osteoarthritis-a-revision-and-a-pilot-study
#11
Isabel Gálvez, Silvia Torres-Piles, María Dolores Hinchado, Alberto Álvarez-Barrientos, Pilar Torralbo-Jiménez, Jorge Guerrero, Leticia Martín-Cordero, Eduardo Ortega
BACKGROUND: Although osteoarthritis has predominantly been considered a non-inflammatory degenerative arthropathy, there is growing evidence that various inflammatory and immunological processes might contribute to the onset, progression, and burden of the disease. OBJECTIVE: The purpose of the present investigation was to study the systemic inflammatory and stress responses and the innate response mediated by neutrophils in OA patients. METHOD: A group of patients diagnosed with primary OA according to the American College of Rheumatology criteria and a control group of age-matched healthy volunteers were enrolled in the study...
March 20, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/28321302/impact-of-health-portal-enrolment-with-email-reminders-at-an-academic-rheumatology-clinic
#12
Arielle Mendel, Shirley Chow
Missed appointments reduce the quality, safety and efficiency of healthcare delivery. 'No-Shows' (NS) have been identified as a problem within the rheumatology clinic at Sunnybrook Health Sciences Center in Toronto, Ontario. NS were studied through a prospective chart review and telephone interviews. Over 6 months, 110 NS took place (rate 2.5-6.8%). From interviews, 85% of NS were attributed to forgetting, being unaware of the appointment, having the wrong date, or another miscommunication. Fifty-seven percent of patients were interested in an appointment reminder, including electronic reminders (46%)...
2017: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/28319603/the-path-of-interchangeability-of-biosimilars-in-pediatric-inflammatory-bowel-disease-quality-before-cost-savings
#13
Dimple Patel, K T Park
The advent of biosimilars in inflammatory bowel disease (IBD) represents an opportunity for cost-savings and increased patient access to effective disease-modifying therapies. While preliminary data in adult IBD and rheumatology patients suggest comparable effectiveness and pharmacokinetics between original biologics and biosimilars, long-term immunogenicity data are unknown. Without this data, conclusions about interchangeability should not be made for pediatric patients with IBD. Children affected by IBD, in particular, are a vulnerable group if automatic substitution and non-medical switching are allowed based on limited data in adult patients...
March 17, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28319486/igg4-related-disease
#14
Emanuele Bozzalla Cassione, John H Stone
PURPOSE OF REVIEW: Remarkable insights have been gleaned recently with regard to the pathophysiology of IgG4-related disease (IgG4-RD). These findings have direct implications for the development of targeted strategies for the treatment of this condition. RECENT FINDINGS: Oligoclonal expansions of cells of both the B and T lymphocyte lineages are present in the blood of patients with IgG4-RD. Oligoclonal expansions of plasmablasts are a good biomarker for disease activity...
March 17, 2017: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/28317249/getting-back-to-the-dissecting-room-an-evaluation-of-an-innovative-course-in-musculoskeletal-anatomy-for-uk-based-rheumatology-training
#15
Tim Blake, Debbi Marais, Andrew B Hassell, Kay Stevenson, Zoe Paskins
BACKGROUND: The rheumatologist relies heavily on clinical skills to diagnose diverse conditions, something that is correlated with one's knowledge of clinical anatomy. More recently, rheumatology has offered further career flexibility with opportunities to develop skills such as joint injection and musculoskeletal (MSK) ultrasound, both of which require a sound understanding of anatomy. Currently, there are no formal strategies to support competency-based anatomy learning in rheumatology in the UK...
March 20, 2017: Musculoskeletal Care
https://www.readbyqxmd.com/read/28316855/central-nervous-system-involvement-in-henoch-schonlein-purpura-in-children-and-adolescents
#16
Iliyana H Pacheva, Ivan S Ivanov, Krastina Stefanova, Elena Chepisheva, Lyubov Chochkova, Dafina Grozeva, Angelina Stoyanova, Stojan Milenkov, Penka Stefanova, Anna Petrova
Central nervous system (CNS) involvement in Henoch-Schonlein purpura (HSP) is rare but poses diagnostic difficulties. The aim of the study was to establish the frequency of CNS involvement in HSP, to analyze its clinical characteristics and do a literature review. Medical files of patients with HSP admitted at the Department of Pediatrics, Plovdiv, were studied retrospectively for a five-year period (2009-2013). Diagnosis was based on the American College of Rheumatology criteria. Out of 112 children with HSP 1 case (0...
2017: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/28315284/the-potential-of-established-fitness-cut-off-points-for-monitoring-women-with-fibromyalgia-the-al-%C3%A3-ndalus-project
#17
José Castro-Piñero, Virginia A Aparicio, Fernando Estévez-López, Inmaculada C Álvarez-Gallardo, Milkana Borges-Cosic, Alberto Soriano-Maldonado, Manuel Delgado-Fernández, Víctor Segura-Jiménez
The aim of the present study was to determinate whether fitness cut-off points discriminate the severity of major fibromyalgia symptoms and health-related quality of life. Additionally, we investigated which American Colleague of Rheumatology (ACR) fibromyalgia criteria (1990 vs. modified 2010) better discriminate fibromyalgia symptomatology. A total of 488 women with fibromyalgia and 200 non-fibromyalgia (control) women participated. All participants underwent both the 1990 and the modified 2010 ACR preliminary criteria (hereinafter 1990c and m-2010c, respectively)...
March 17, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28303747/self-reported-physical-capacity-and-activity-in-patients-with-systemic-sclerosis-and-matched-controls
#18
H Pettersson, A Åkerström, A Nordin, E Svenungsson, H Alexanderson, C Boström
OBJECTIVE: The aim was to investigate differences in self-reported physical capacity and activity between systemic sclerosis (SSc) patients and population-based controls, as well as between patients with normal-mild, or moderate-severe, lung disease and their respective controls. METHOD: The study included 106 patients fulfilling the American College of Rheumatology SSc criteria and 106 controls, individually matched for age and gender. Patients were subdivided into normal-mild and moderate-severe lung disease based on results from pulmonary function tests and SSc severity scale...
March 17, 2017: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28299916/relationship-between-patient-reported-and-objective-measurements-of-hand-function-in-patients-with-rheumatoid-arthritis
#19
S M Günay, Z Tuna, D Oskay
Rheumatoid arthritis (RA) often results in impairments in upper extremities, especially in the small joints of hand. Involvement of hand brings limitations in activities of daily living. However, it is commonly observed that patient-reported functional status of hand does not always corresponds to their actual physical performance in the clinical setting. The aim of this pilot study is to investigate the relationship between patient self-reported and objectively measured hand functions in patients with RA. Twenty-six patients (51±13 years) with RA diagnosis participated in the study...
December 31, 2016: Reumatismo
https://www.readbyqxmd.com/read/28299624/examining-the-relationship-between-pain-catastrophizing-and-suicide-risk-in-patients-with-rheumatic-disease-the-mediating-role-of-depression-perceived-social-support-and-perceived-burdensomeness
#20
Eun -Jung Shim, Yeong Wook Song, Seung-Hee Park, Kwang-Min Lee, Dong Jin Go, Bong-Jin Hahm
PURPOSE: Little research has examined the role of pain catastrophizing (PC) in predicting suicide among patients with rheumatic disease or the mechanisms through which it works. This study examines whether depression, perceived social support (PSS), and perceived burdensomeness (PB) mediate the relationship between PC and suicide risk. It also examines the relative importance of sociodemographic, clinical, and psychological factors in predicting suicide risk. METHODS: Three hundred sixty patients from a rheumatology clinic in Korea completed measures of pain catastrophizing, social support, depression, and perceived burdensomeness...
March 15, 2017: International Journal of Behavioral Medicine
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