keyword
MENU ▼
Read by QxMD icon Read
search

Medullary

keyword
https://www.readbyqxmd.com/read/29244687/pilon-fractures-of-the-base-of-the-proximal-phalanx-direct-intraosseous-joint-reduction-with-bone-grafting-and-mini-screws-a-case-report
#1
Iva Neshkova, Rainer H Meffert
CASE: A 31-year-old woman sustained a closed pilon fracture of the base of the second proximal phalanx. Computed tomography showed comminution, central depression, and splaying of the articular surface. We used a method of direct intraosseous joint reduction in combination with bone-grafting and mini-screws to treat the fracture. For reduction, a golf-club-shaped instrument was inserted into the medullary cavity through a drill-hole in the phalanx. CONCLUSION: The advantage of this technique is that it leaves the joint capsular complex and the extensor hood intact...
January 2017: JBJS Case Connector
https://www.readbyqxmd.com/read/29244667/periosteal-ewing-sarcoma-in-a-65-year-old-man-a-case-report
#2
Julia Bedard, Jessica Burns, Amalia de Comas
CASE: Ewing sarcoma is predominantly a pediatric bone malignancy involving the medullary canal. Periosteal Ewing sarcoma, a subtype arising from the periosteum, is exceedingly rare, with approximately 30 reported cases in the literature. We describe a case of periosteal Ewing sarcoma in the tibia of a 65-year-old man. Magnetic resonance imaging revealed a heterogeneous mass in the proximal tibial diaphysis without medullary involvement. The diagnosis was confirmed histologically after biopsy...
April 2017: JBJS Case Connector
https://www.readbyqxmd.com/read/29244598/associations-of-patient-characteristics-disease-stage-and-biopsy-technique-with-the-diagnostic-quality-of-core-needle-renal-biopsy-specimens-from-dogs-with-suspected-kidney-disease
#3
Leandro Z Crivellenti, Rachel Cianciolo, Thomas Wittum, George E Lees, Christopher A Adin
OBJECTIVE To identify factors affecting the diagnostic quality of core needle renal biopsy specimens from dogs with suspected kidney disease. DESIGN Cross-sectional study. ANIMALS 522 client-owned dogs with suspected kidney disease for which core needle renal biopsy specimens (n = 1,089) were submitted to the International Veterinary Renal Pathology Service for evaluation and inclusion in their database. PROCEDURES Data regarding dog signalment, clinical variables, biopsy method, needle brand and gauge, biopsy results, and other variables were extracted from the database...
January 1, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29243843/signaling-cascades-in-thyroid-cancer-increasing-the-armory-of-archers-to-hit-bullseye
#4
Faiza Abdul Rashid, Qaisar Mansoor, Hafsa Aziz, Sobia Tabassum, Waleed O Arfat, George E Naoum, Muhammad Ismail, Ammad Ahmad Farooqi
Thyroid cancer is a multifaceted and therapeutically challenging disease and rapidly accumulating experimentally verified findings have considerably improve our understanding of the molecular mechanisms which underlie its development. Substantial fraction of information has been added into existing landscape of molecular oncology and we have started to develop a sharper understanding of the underlying mechanisms of thyroid cancer. Wealth of information demystified different intracellular signaling cascades which are frequently deregulated in thyroid cancer...
December 15, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29243797/rapamycin-induces-human-acute-promyelocytic-leukemia-cell-hl-60-autophagic-apoptosis
#5
Y-H Zhang, Q-F Lin, X-L Wang, Q-Y Li, J-J Chai, X-J Fan
OBJECTIVE: We aimed at investigating the effects of rapamycin on apoptosis and autophagy of human acute promyelocytic leukemia cell line HL-60, and to preliminarily explore the mechanism of extra medullary infiltration of leukemia cells with human acute promyelocytic leukemia cell line HL-60 as the object of study, providing a theoretical basis for the clinical treatment of leukemia. MATERIALS AND METHODS: After HL-60 cells were cultured in vitro, the effect of rapamycin on proliferation ability of HL-60 cells was determined by methyl thiazolyl tetrazolium (MTT) method, the cell apoptosis ratio was detected by flow cytometer, the change of autophagy after HL-60 cells acted by rapamycin was tested by monodansylcadaverine (MDC) fluorescence staining, the mRNA expression of autophagy-related molecule was detected by polymerase chain reaction (PCR), and the expressions of apoptosis-related protein and autophagy-related protein were determined by Western blotting (WB)...
December 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29241816/triple-bundle-anatomical-reconstruction-using-the-coracoacromial-ligament-and-the-short-head-of-biceps-tendon-to-stabilize-chronic-acromioclavicular-joint-dislocations-a-cadaver-feasibility-study
#6
M Le Hanneur, D Delgrande, T Lafosse, J-D Werthel, P Hardy, B Elhassan
INTRODUCTION: In cases of chronic acromioclavicular joint separation, the biomechanical properties of anatomical reconstructions are closer to the native configuration than the Weaver-Dunn procedure. Consequently, the radiological and clinical outcomes are better. However, an additional incision is needed to harvest the graft, which increases the procedure's morbidity. HYPOTHESIS: Triple-bundle reconstruction can be performed with the coracoacromial ligament (CAL) and the semi conjoined tendon (SCT)...
December 11, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29241209/lateral-medullary-infarction-caused-by-oriental-acupuncture
#7
Soonwoong Hong, YoonAh Park, Chan-Nyoung Lee
No abstract text is available yet for this article.
December 14, 2017: European Neurology
https://www.readbyqxmd.com/read/29240901/daily-social-interactions-and-the-biological-stress-response-are-there-age-differences-in-links-between-social-interactions-and-alpha-amylase
#8
Kira S Birditt, Lauren A Tighe, Michael R Nevitt, Steven H Zarit
Background and Objectives: According to the strength and vulnerability integration (SAVI) model, older people are better able to avoid negative social interactions than younger people, but when they do experience negative interactions, they are equally or more emotionally and physiologically reactive than younger people. Less is known about the links between daily negative and positive social encounters and the sympathetic adrenal medullary system (a key stress pathway) and whether there are age differences in these links...
December 12, 2017: Gerontologist
https://www.readbyqxmd.com/read/29240016/drainage-of-cerebrospinal-fluid-and-blood-pressure-augmentation-as-rescue-therapies-for-ischemic-myelitis-after-bronchial-embolization-a-case-report
#9
Pierre-Alexis Lépine, Jean-François Naud, Philippe Boisvert
A 62-year-old man presented to the emergency department with massive hemoptysis. After bronchial artery embolization, he developed ischemic myelitis, a rare complication in this setting for which no specific therapy is currently recommended. The symptoms were managed with lumbar drainage of cerebrospinal fluid and blood pressure augmentation therapy. To our knowledge, this is the first report of using lumbar drainage of cerebrospinal fluid and blood pressure augmentation in the treatment of anterior medullary ischemia after bronchial artery embolization for massive hemoptysis...
December 11, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/29239042/special-types-of-thyroid-carcinoma
#10
REVIEW
Zubair W Baloch, Virginia A LiVolsi
This article reviews the small percentage of thyroid tumours that are not classified as classic papillary thyroid carcinoma, follicular thyroid carcinoma, and medullary thyroid carcinoma. It includes subtypes of papillary thyroid carcinoma, including, tall-cell, hobnail/micropapillary, columnar cell, diffuse sclerosing and solid variants. Poorly differentiated carcinoma, high-grade carcinoma and anaplastic thyroid carcinoma are reviewed. Also discussed are entities that are unusual but need to be recognized as primary thyroid neoplasms, i...
January 2018: Histopathology
https://www.readbyqxmd.com/read/29239041/hereditary-and-familial-thyroid-tumours
#11
REVIEW
Julie Guilmette, Vania Nosé
The worldwide incidence of thyroid malignancies has been increasing rapidly. Sensitive imaging modalities and early detection of thyroid lesions have made thyroid cancers the most rapidly increasing cancers in the USA in 2017 (SEER Cancer Facts, 2017). Clinical awareness of potential risk factors, such as inherited thyroid cancers, has allowed earlier recognition of more vulnerable population clusters. Hereditary thyroid neoplasms arising from calcitonin-producing C cells are known as familial medullary thyroid carcinomas (FMTCs), and include well-documented syndromes such as multiple endocrine neoplasia IIA or IIB, and pure familial medullary thyroid carcinoma syndrome...
January 2018: Histopathology
https://www.readbyqxmd.com/read/29237740/grhl2-is-required-for-collecting-duct-epithelial-barrier-function-and-renal-osmoregulation
#12
Christian Hinze, Janett Ruffert, Katharina Walentin, Nina Himmerkus, Elham Nikpey, Olav Tenstad, Helge Wiig, Kerim Mutig, Zeliha Yesim Yurtdas, Janet D Klein, Jeff M Sands, Federica Branchi, Michael Schumann, Sebastian Bachmann, Markus Bleich, Kai M Schmidt-Ott
Collecting ducts make up the distal-most tubular segments of the kidney, extending from the cortex, where they connect to the nephron proper, into the medulla, where they release urine into the renal pelvis. During water deprivation, body water preservation is ensured by the selective transepithelial reabsorption of water into the hypertonic medullary interstitium mediated by collecting ducts. The collecting duct epithelium forms tight junctions composed of barrier-enforcing claudins and exhibits a higher transepithelial resistance than other segments of the renal tubule exhibit...
December 13, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/29237738/ascending-vasa-recta-are-angiopoietin-tie2-dependent-lymphatic-like-vessels
#13
Yael Kenig-Kozlovsky, Rizaldy P Scott, Tuncer Onay, Isabel Anna Carota, Benjamin R Thomson, Hyea Jin Gil, Veronica Ramirez, Shinji Yamaguchi, Christine E Tanna, Stefan Heinen, Christine Wu, Radu V Stan, Janet D Klein, Jeff M Sands, Guillermo Oliver, Susan E Quaggin
Urinary concentrating ability is central to mammalian water balance and depends on a medullary osmotic gradient generated by a countercurrent multiplication mechanism. Medullary hyperosmolarity is protected from washout by countercurrent exchange and efficient removal of interstitial fluid resorbed from the loop of Henle and collecting ducts. In most tissues, lymphatic vessels drain excess interstitial fluid back to the venous circulation. However, the renal medulla is devoid of classic lymphatics. Studies have suggested that the fenestrated ascending vasa recta (AVRs) drain the interstitial fluid in this location, but this function has not been conclusively shown...
December 13, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/29237502/initial-clinical-presentation-of-single-soft-tissue-metastasis-of-medullary-thyroid-carcinoma-without-primary-tumor-in-the-thyroid-gland
#14
Masanori Okamoto, Akira Takazawa, Kaoru Aoki, Yasuo Yoshimura, Hiroyuki Kato, Toshiaki Otsuki, Kazuma Maeno, Tomonobu Koizumi
BACKGROUND: Single soft tissue metastasis of medullary thyroid carcinoma is extremely rare. In addition, several occult medullary thyroid carcinomas with distant metastasis were reported, but undetectable primary lesion at diagnosis was also extremely rare. CASE PRESENTATION: A 74-year-old man was admitted to our hospital because of a painful nodule in his left buttock for over 1 year. Needle biopsy was performed, and the histological findings revealed adenocarcinoma positive for thyroid transcription factor-1...
December 13, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29236672/setting-up-the-perimeter-of-tolerance-insights-into-mtec-physiology
#15
Pedro M Rodrigues, Pärt Peterson, Nuno L Alves
Medullary thymic epithelial cells (mTECs) play a central role in T cell tolerance. However, how the mTEC compartment is maintained remains elusive. We review recent discoveries on new transcription factors involved in mTEC homeostasis and discuss the possibility that their actions might be facilitated by the unique biology of mTECs.
November 24, 2017: Trends in Immunology
https://www.readbyqxmd.com/read/29236342/longitudinal-assessment-of-rabbit-renal-fibrosis-induced-by-unilateral-ureteral-obstruction-using-two-dimensional-susceptibility-weighted-imaging
#16
Jing-Gang Zhang, Zhao-Yu Xing, Ting-Ting Zha, Xiao-Juan Tian, Ya-Nan Du, Jie Chen, Wei Xing
BACKGROUND: Previous studies indicated that two-dimensional-susceptibility weighted imaging (2D-SWI) could serve as a useful biomarker for differentiating the grade of liver fibrosis. PURPOSE: To evaluate the feasibility of 2D-SWI in the dynamic quantification of renal fibrosis in a rabbit model. STUDY TYPE: Longitudinal study. ANIMAL MODEL: Twenty-Four New Zealand White Rabbits including control group (n = 4); and renal fibrosis group (n = 20), by means of a unilateral ureteral obstruction (UUO) model...
December 13, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29234625/insight-into-differentiated-thyroid-cancer-gross-pathological-specimen-shrinkage-and-its-influence-on-tnm-staging
#17
Alexis Lacout, Emmanuel Chamorey, Juliette Thariat, Mostafa El Hajjam, Carole Chevenet, Renaud Schiappa, Pierre Yves Marcy
Introduction: This study aimed at comparing thyroid cancer staging when taking into account the differences between the "T" assessment" using ultrasound (US) and histopathological measurements. Material and Methods: This retrospective study included all consecutive differentiated follicular thyroid cancer (DTC) and medullary thyroid cancer (MTC) patients who underwent postoperative histopathological staging assessment at a single institution. Anaplastic thyroid carcinomas were excluded from the present study...
November 2017: European Thyroid Journal
https://www.readbyqxmd.com/read/29232953/mitochondrial-signs-and-subcellular-imaging-imply-the-antifungal-mechanism-of-carabrone-against-gaeumannomyces-graminis-var-tritici
#18
Lanying Wang, Yunfei Zhang, Delong Wang, Mei Wang, Yong Wang, Juntao Feng
Carabrone, a botanical bicyclic sesquiterpenic lactone, has broad-spectrum antifungal activities, and is particularly efficient against the devastating phytopathogen Gaeumannomyces graminis var.tritici (Ggt). The antifungal mechanism of carabrone against Ggt, however, remains unclear. The main objective of this study was to investigate the subcellular localization of carabrone in Ggt to make a better understanding of the mechanism of action. When Ggt was exposed to carabrone (EC50 value, 28.45 μg/mL) for 7 days, the decline of mitochondrial concentration, together with some obvious alternations in the mitochondrial structure including hazy outline, medullary transition, excess accumulation of unclear settlings, and vacuolar degeneration were observed, indicating that carbrone may act on the mitochondria directly...
December 12, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29231762/haemolytic-anaemia-and-hepatocitolysis-associated-with-hypermagnesaemia-by-repeated-exposures-to-copper-calcium-fungicides
#19
Constantin Bălăeţ, Bogdan Ioan Coculescu, Maria Bălăeţ, Gheorghe Manole, Gabi Valeriu Dincă
For the medical practice, our manuscript acts as a signal, despite only presenting three cases which feature the association between hepatocytolysis, haemolysis and hypermagnesaemia. This clinical-biologic triad was highlighted with the workers who through the nature of their profession were exposing themselves periodically to vapours which contained copper sulphate neutralised with calcium hydroxide, a fungicide used for fruit trees. We are exclusively assessing the haematological perturbation. In this aetiological context, the generating mechanism for haemolysis is very probable biochemical, where hypercupraemia interferes with cellular antioxidant defence mechanisms...
December 2018: Journal of Enzyme Inhibition and Medicinal Chemistry
https://www.readbyqxmd.com/read/29231613/-effects-of-electroacupuncture-on-expression-of-%C3%AE-opioid-receptor-in-nucleus-ceruleus-in-rats-with-bone-cancer-pain-morphine-tolerance
#20
Taofang Fu, Lingling Wang, Junying Du, Feng Chen, Junfan Fang, Yi Liang, Jianqiao Fang
OBJECTIVE: To observe the effects of electroacupuncture (EA) on pain behavior in rats with bone cancer pain and morphine tolerance, and to explore partial action mechanism. METHODS: Forty-two SD healthy female rats were randomly divided into a sham operation group (7 rats), a bone cancer pain group (8 rats), a morphine tolerance group (9 rats), an EA group (9 rats) and a sham EA group (9 rats). The rats in the sham operation group were treated with injection of phosphate buffer saline at medullary cavity of left-side tibia, and the rats in the remaining groups were injected with MRMT-1 breast cancer cells...
May 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
keyword
keyword
87986
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"