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https://www.readbyqxmd.com/read/28723970/barriers-and-facilitators-of-hiv-vaccine-and-prevention-study-participation-among-young-black-msm-and-transwomen-in-new-york-city
#1
Sharise Richardson, Pich Seekaew, Beryl Koblin, Tasha Vazquez, Vijay Nandi, Hong-Van Tieu
BACKGROUND: Black men who have sex with men (MSM), and Transwomen (TW) shoulder disproportionate burden of HIV. However, they are unrepresented in HIV vaccine trials. We investigated the perceptions of that factors associated with HIV vaccine trials participation among Black MSM and TW in New York. METHODS: Self-administered online questionnaires were administered to 18-29 years of NYC residents who identified as Black MSM and TW, assessing demographics, awareness and willingness to participate in HIV vaccine trials, barriers and facilitators associated with willingness, and sexual behaviors...
2017: PloS One
https://www.readbyqxmd.com/read/28712040/the-effect-of-targeted-therapy-for-genitourinary-malignancies-on-sexual-function-and-fertility
#2
REVIEW
Bradley C Holland, Zubin Shetty, Shaheen Alanee
PURPOSE OF REVIEW: Targeted therapy for genitourinary cancer is being used at an increasing rate. These medications show great survival benefit but are relatively lacking in long-term adverse effect data. With increasing survivability, measures to improve quality of life must be considered for GU cancer and a large proponent of this is sexual function. RECENT FINDINGS: mTOR inhibitors have shown an effect on testosterone levels and may have a link to abnormal semen parameters...
August 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28696345/optimal-hiv-postexposure-prophylaxis-regimen-completion-with-single-tablet-daily-elvitegravir-cobicistat-tenofovir-disoproxil-fumarate-emtricitabine-compared-with-more-frequent-dosing-regimens
#3
Kenneth H Mayer, Daniel Jones, Catherine Oldenburg, Sachin Jain, Marcy Gelman, Shayne Zaslow, Chris Grasso, Matthew J Mimiaga
STRUCTURE: The study evaluated elvitegravir/cobicistat/tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC) ("Quad pill") for postexposure prophylaxis (PEP). BACKGROUND: HIV-exposed individuals may benefit from PEP, but completion rates have been suboptimal because of regimen complexity and side effects. Newer antiretroviral combinations coformulated as single daily pills may optimize PEP adherence. SETTING: One hundred HIV-uninfected individuals who presented to a Boston community health center after an acute HIV sexual exposure were enrolled and initiated PEP with the daily, single-pill combination Quad pill for a 28-day course...
August 15, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28691439/awareness-and-willingness-to-use-hiv-pre-exposure-prophylaxis-among-men-who-have-sex-with-men-in-low-and-middle-income-countries-a-systematic-review-and-meta-analysis
#4
Siyan Yi, Sovannary Tuot, Grace W Mwai, Chanrith Ngin, Kolab Chhim, Khoundyla Pal, Ewemade Igbinedion, Paula Holland, Sok Chamreun Choub, Gitau Mburu
INTRODUCTION: To facilitate provision of pre-exposure prophylaxis (PrEP) in low- and middle-income countries (LMIC), a better understanding of potential demand and user preferences is required. This review assessed awareness and willingness to use oral PrEP among men who have sex with men (MSM) in LMIC. METHODS: Electronic literature search of Cochrane library, Embase, PubMed, PsychINFO, CINHAL, Web of Science, and Google Scholar was conducted between July and September 2016...
June 26, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28679189/pharmacological-dynamic-rehabilitative-behavioural-therapy-for-premature-ejaculation-results-of-a-pilot-study
#5
Franco Mantovani
OBJECTIVES: Premature ejaculation (PE) is a sexual disorder characterised by excessive rapidity of orgasm. It is defined as either primary (60%), present since the onset of sexual activity, or secondary (40%), manifesting later in life. To date, dapoxetine is the only preparation approved for the on-demand treatment of PE. However, side effects, costs associated with the treatment of chronic PE, drug dependence and its variable effectiveness leads to a not insignificant drop-out rate...
June 30, 2017: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28674645/infestation-of-parasitic-rhizocephalan-barnacles-sacculina-beauforti-cirripedia-rhizocephala-in-edible-mud-crab-scylla-olivacea
#6
Khor Waiho, Hanafiah Fazhan, Henrik Glenner, Mhd Ikhwanuddin
Screening of mud crab genus Scylla was conducted in four locations (Marudu Bay, Lundu, Taiping, Setiu) representing Malaysia. Scylla olivacea with abnormal primary and secondary sexual characters were prevalent (approximately 42.27% of the local screened S. olivacea population) in Marudu Bay, Sabah. A total of six different types of abnormalities were described. Crabs with type 1 and type 3 were immature males, type 2 and type 4 were mature males, type 5 were immature females and type 6 were mature females...
2017: PeerJ
https://www.readbyqxmd.com/read/28670890/a-cross-sectional-study-on-knowledge-attitude-and-practice-related-to-human-papillomavirus-vaccination-for-cervical-cancer-prevention-between-medical-and-non-medical-students-in-hong-kong
#7
Pui Woo Angela Yam, Pak Lun Lam, Tsz Kin Chan, Kei Wai Chau, Mei Lam Hsu, Yat Man Lim, Chun Hin Lo, Lincoln Siu, Hiu Fung Tang, Ann Marie Jing Man Tong, Wai Lok Yeung
Background: One of the most important aetiologies of cervical cancer is Human Papillomavirus (HPV) infection. While vaccination is an effective way in preventing high risk HPV infection, HPV vaccine uptake rate in Hong Kong has been low. Considering the proven effectiveness of HPV vaccination and the low vaccination uptake rate in Hong Kong, this study was conducted to compare the knowledge, attitude and practice towards HPV vaccination for cervical cancer prevention between medical and non-medical students in the University of Hong Kong...
June 25, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28665237/genital-angiokeratomas-of-fordyce-595-nm-variable-pulse-pulsed-dye-laser-treatment
#8
Ján Baumgartner, Mária Šimaljaková
BACKGROUND: Angiokeratoma of Fordyce (AF) are dark red or blue-black papules with scaly surface located on scrotum, labia majora and penis. Though usually asymptomatic, bleeding after mechanical trauma and sexual intercourse may occure. AF should be differentiated from malignant melanoma, angiosarcoma and other pigmented lesions. The treatment, usually asked from patients as the result of anxiety and social embarrassment should be performed in an non-aggresive manner. OBJECTIVES: To determine the safety and effectiveness of 595-nm variable-pulse pulsed dye laser (VPPDL) with Dynamic Cooling Device (DCD) in treatment of AF...
June 30, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28661259/gonadotrophin-releasing-hormone-agonist-treatment-for-sexual-offenders-a-systematic-review
#9
Alexandra Lewis, Don Grubin, Callum C Ross, Mrigendra Das
BACKGROUND: Sexual offending is a significant international issue causing long-term consequences for victims, perpetrators and society. AIMS: The purpose of this study was to review the existing research data assessing the efficacy of gonadotrophin-releasing hormone agonists for treating adult, male, sexual offenders. METHOD: The method of this review involved the examination of studies involving participants prescribed at least one month of a gonadotrophin-releasing hormone agonist for the purposes of reducing sexual drive related to offending...
June 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28660567/the-best-of-both-worlds-an-example-mixed-methods-approach-to-understand-men-s-preferences-for-the-treatment-of-lower-urinary-tract-symptoms
#10
Divine Ikenwilo, Sebastian Heidenreich, Mandy Ryan, Colette Mankowski, Jameel Nazir, Verity Watson
BACKGROUND: Discrete choice experiments (DCEs) are widely used to quantify individuals' preferences for healthcare. Guidelines recommend the design of DCEs should be informed by qualitative research. However, only a few studies go beyond guidelines by fully presenting qualitative and quantitative research jointly together in a mixed methods approach (MMA). OBJECTIVES: Using an example study about men's preferences for medical treatment of lower urinary tract symptoms (LUTS), we demonstrate how qualitative research can complement DCEs to gain a rich understanding of individuals' preferences...
June 28, 2017: Patient
https://www.readbyqxmd.com/read/28652166/multilingual-self-management-resources-for-prostate-cancer-survivors-and-their-partners-results-of-a-long-term-academic-state-health-department-partnership-to-promote-survivorship-care
#11
Ted A Skolarus, Jennifer A Ragnoni, Carol Garlinghouse, Ann Schafenacker, Debbie Webster, Polly Hager, Daniela Wittmann, Laurel Northouse
INTRODUCTION: There is increasing need for innovative, sustainable ways to provide evidence-based self-management information and supportive care for prostate cancer survivors and their partners. For these reasons, we describe how an academic-public partnership facilitated the broad dissemination of evidence-based, multilingual survivorship educational materials via a state-managed prostate cancer website. METHODS: We outline the steps of an academic-public partnership leading to dissemination of online, survivorship materials as a resource for prostate cancer survivors and their partners...
June 23, 2017: Urology
https://www.readbyqxmd.com/read/28650227/facilitators-and-barriers-to-participation-in-prep-hiv-prevention-trials-involving-transgender-male-and-female-adolescents-and-emerging-adults
#12
Celia B Fisher, Adam L Fried, Margaret Desmond, Kathryn Macapagal, Brian Mustanski
Despite the disproportionate burden of HIV facing transgender youth, they continue to be under-represented in studies to provide an empirical basis for pre-exposure prophylaxis (PrEP) programs that can meet the unique needs of this population. This study examined facilitators and barriers to participation in a PrEP adherence study, determined through an online survey administered to 90 transgender male and 60 transgender female 14-21-year-olds attracted to cisgender male sexual partners. Approximately 50% reported likely to participate in the PrEP study...
June 2017: AIDS Education and Prevention: Official Publication of the International Society for AIDS Education
https://www.readbyqxmd.com/read/28648486/focal-brachytherapy-for-localized-prostate-cancer-urinary-toxicity-depends-on-tumor-location
#13
Victor Srougi, Eric Barret, Igor Nunes-Silva, Mohammed Baghdadi, Silvia Garcia-Barreras, Noelle Pierrat, Francois Rozet, Marc Galiano, Rafael Sanchez-Salas, Xavier Cathelineau, Jean-Marc Cosset
PURPOSE: To evaluate whether patients with prostate cancer have worse functional urinary recovery with focal brachytherapy (FBT) at the base versus the apex of the prostate. METHODS AND MATERIALS: The functional outcomes of patients treated with FBT at the base of the prostate were compared with those of patients treated with FBT at the apex. Urinary symptoms, continence, and erectile dysfunction were measured using the International Prostate Symptom Score (IPSS), International Continence Score (ICS), and International Index of Erectile Function (IIEF-5) questionnaires, respectively, at baseline and at 6, 12, and 24 months after treatment...
June 22, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28647404/patient-centered-outcomes-and-treatment-preferences-regarding-sexual-problems-a-qualitative-study-among-midlife-women
#14
Holly N Thomas, Megan Hamm, Rachel Hess, Sonya Borrero, Rebecca C Thurston
BACKGROUND: Sexual dysfunction is common in midlife women and can have a significant negative impact on quality of life. Although treatments exist, there is little research on which sexual function outcomes and treatments midlife women prefer. AIM: To better understand the sexual function outcomes that were most important to sexually active women 45 to 60 years old and the types of treatments they would prefer from individual interviews and focus groups. METHODS: Twenty individual interviews and three focus groups (N = 39) were led by a trained facilitator, audio recorded, and transcribed...
June 21, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28642048/sexual-consequences-of-post-ssri-syndrome
#15
REVIEW
Yacov Reisman
INTRODUCTION: Sexual dysfunctions are well-known side effects of selective serotonin reuptake inhibitor (SSRI) use. Altered libido, erectile dysfunction, vaginal dryness, ejaculatory disorders, and orgasmic problems are frequently reported by patients treated with SSRIs. Moreover, these antidepressant-emergent sexual dysfunctions do not always resolve after discontinuation of the medication and can persist indefinitely. These complaints are termed post-SSRI sexual dysfunctions (PSSD)...
June 19, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28640161/combined-data-of-intravaginal-prasterone-against-vulvovaginal-atrophy-of-menopause
#16
Fernand Labrie, David F Archer, Céline Martel, Mario Vaillancourt, Marlene Montesino
OBJECTIVE: To analyze the effects of intravaginal prasterone obtained in the three randomized clinical studies performed in postmenopausal women suffering from moderate to severe (MS) dyspareunia due to vulvovaginal atrophy (VVA). METHODS: In three independent 12-week prospective, randomized, double-blind, and placebo-controlled clinical studies, the effect of daily intravaginal 0.50% (6.5 mg) prasterone was examined on four co-primary objectives in women having MS pain during sexual activity (dyspareunia), identified as their most bothersome symptom (MBS) of VVA at baseline...
June 19, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28637417/effect-of-heteropterys-aphrodisiaca-on-anxiety-and-male-exposure-of-female-mice-with-advanced-age
#17
Daniela Miranda Farias, Maria Silvia Ostetto, Rozimeri Colleti, Thais Barbosa, Jorge Aparecido Barros, Sergio Machado, Eric Murillo-Rodríguez, Susana E Moreno, André Barciela Veras
BACKGROUND: Effect of Heteropterys aphrodisiac (dog-node) on anxiety and function Of adult female wistar mice. The Project is an experiment with the use of Of H. aphrodisiac root extract, in order to observe the frequency of Sexual exposure of females exposed to the extract, quantify the effect of the extract on the Concentration of total testosterone and observe the anxiety levels of the animals Exposed. Results will be measured with the laboratory testosterone test and LCE and CA tests...
June 21, 2017: Current Clinical Pharmacology
https://www.readbyqxmd.com/read/28635978/vaginal-testosterone-for-management-of-aromatase-inhibitor-related-sexual-dysfunction-an-integrative-review
#18
Emily A Lemke, Lydia T Madsen, Joyce E Dains
PROBLEM IDENTIFICATION: Women taking aromatase inhibitors (AIs) as part of the management of hormone receptor-positive breast cancer experience more symptoms of sexual dysfunction, including vaginal atrophy, as opposed to postmenopausal women and women treated with tamoxifen (Nolvadex®). Vaginal testosterone could be an alternative to estrogen, which is contraindicated in this population.
. LITERATURE SEARCH: A systematic review was completed by searching PubMed and Scopus databases...
May 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28632494/long-term-dutasteride-therapy-in-men-with-benign-prostatic-hyperplasia-alters-glucose-and-lipid-profiles-and-increases-severity-of-erectile-dysfunction
#19
Abdulmaged Traish, Karim Sultan Haider, Gheorghe Doros, Ahmad Haider
Background Dutasteride has been successfully used in treatment of lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). However, dutasteride inhibits 5α-reductase type 1 and type 2 enzymes and may compromises glucocorticoids and androgen metabolism and alters metabolic function resulting in undesirable metabolic and sexual adverse side effects. Aim The aim of this study was to investigate the long-term adverse effects of dutasteride therapy in men with BPH on: i) blood glucose, ii) glycated hemoglobin (HbA1c), iii) low density lipoprotein-cholesterol (LDL-C); high density lipoprotein-cholesterol (HDL-C) and total cholesterol (TC), iv) testosterone (T), v) liver alanine and aspartate aminotransferases (ALT and AST) and vi) erectile dysfunction (ED)...
June 21, 2017: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/28622159/weeding-out-the-justification-for-marijuana-treatment-in-patients-with-developmental-and-behavioral-conditions
#20
Theodora Nelson, Yi Hui Liu, Kara S Bagot, Martin T Stein
Alex is a 13-year-old adolescent with high-functioning autism spectrum disorder, attention-deficit/hyperactivity disorder (ADHD)-combined type, anxiety, and depression. He has been resistant to engaging in therapy and treatment with various medications has been unsuccessful. Alex's parents are concerned about his anxiety, isolation, oppositional behaviors, academic underachievement, truancy, and substance use. A recent altercation with his stepfather led to a police intervention and a brief removal of Alex from the home...
July 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
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