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https://www.readbyqxmd.com/read/29031306/everyday-life-after-a-radical-prostatectomy-a-qualitative-study-of-men-under-65%C3%A2-years-of-age
#1
Anne Wennick, Ann-Kristin Jönsson, Ola Bratt, Karin Stenzelius
PURPOSE: The purpose of this study was to illuminate how men under 65 years of age experience their everyday Life one year or more after a radical prostatectomy for localised prostate cancer. METHOD: Interviews with 19 men aged under 65 were performed 12-18 months after their radical prostatectomy. The interviews were analysed using a thematic content analysis. RESULTS: The analysis of the interviews revealed three categories of experiences: 'Paying a price for survival', 'Feeling sidestepped' and 'Living with death lurking around the corner'...
October 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28992226/arginine-vasotocin-and-neuropeptide-y-vary-with-seasonal-life-history-transitions-in-garter-snakes
#2
Ashley R Lucas, Daelyn Y Richards, Lucy M Ramirez, Deborah I Lutterschmidt
Transitions between life-history stages are often accompanied by dramatic behavioral switches that result from a shift in motivation to pursue one resource over another. While the neuroendocrine mechanisms that regulate such behavioral transitions are poorly understood, arginine vasotocin (AVT) and neuropeptide Y (NPY) are excellent candidates because they modulate reproductive and feeding behavior, respectively. We asked if seasonal changes in AVT and NPY are concomitant with the seasonal migration to and from the feeding grounds in red-sided garter snakes (Thamnophis sirtalis parietalis)...
August 1, 2017: Integrative and Comparative Biology
https://www.readbyqxmd.com/read/28990535/voluntary-medical-male-circumcision-to-prevent-hiv-in-tanah-papua-indonesia-field-trial-to-assess-acceptability-and-feasibility
#3
M Ridwan Ansari, Elan Lazuardi, Frank Stephen Wignall, Constant Karma, Sylvanus A Sumule, Siti Nadia, Robert Magnani
BACKGROUND: Relatively little attention has been directed to the significant HIV prevention role that voluntary medical male circumcision (VMMC) can play in populations with moderate levels of HIV prevalence. One such location is Tanah Papua, Indonesia, which in 2013 had a general population HIV prevalence of 2.3% concentrated among indigenous Papuans (2.9% prevalence), very few of whom are circumcised. This article reports the findings of an implementation research study assessing the acceptability and feasibility of introducing VMMC for HIV prevention...
October 5, 2017: Current HIV Research
https://www.readbyqxmd.com/read/28978294/experiences-along-the-hiv-care-continuum-perspectives-of-kenyan-adolescents-and-caregivers
#4
Winnie K Luseno, Bonita Iritani, Susannah Zietz, Suzanne Maman, Isabella I Mbai, Florence Otieno, Barrack Ongili, Denise Dion Hallfors
To be effective, HIV programmes should be responsive to the unique needs of diverse groups of infected adolescents. We highlight a range of adolescent perspectives on HIV services, including those who acquired HIV perinatally or sexually and those who were either in care, had dropped out of care, or had never enrolled in care. We conducted semi-structured interviews with 29 adolescents (aged 15-19) and 14 caregivers in western Kenya. Data were analysed using a descriptive analytical approach. Adolescents who were successfully linked had a supportive adult present during diagnosis; tested during hospitalisation or treatment for a recurrent or severe illness; and initiated treatment soon after diagnosis...
September 2017: African Journal of AIDS Research: AJAR
https://www.readbyqxmd.com/read/28970071/low-level-laser-therapy-for-the-treatment-of-provoked-vestibulodynia-a-randomized-placebo-controlled-pilot-trial
#5
Ahinoam Lev-Sagie, Asia Kopitman, Amnon Brzezinski
BACKGROUND: Low-level laser therapy (LLLT) is an emerging medical technology in which non-thermal laser irradiation is applied to treat pain. Because LLLT has been found effective in treating various pain syndromes without known side effects, we conducted a study evaluating the effect of LLLT on provoked vestibulodynia (PVD), a complex sexual pain disorder characterized by pain confined to the vulvar vestibule in response to contact or pressure. AIM: To investigate the effectiveness of LLLT for PVD in a randomized, placebo-controlled, double-blinded trial...
September 29, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28969611/truenth-sexual-recovery-study-protocol-a-multi-institutional-collaborative-approach-to-developing-and-testing-a-web-based-intervention-for-couples-coping-with-the-side-effects-of-prostate-cancer-treatment-in-a-randomized-controlled-trial
#6
D Wittmann, A Mehta, L Northouse, R Dunn, T Braun, A Duby, L An, L Arab, R Bangs, S Bober, J Brandon, M Coward, M Dunn, M Galbraith, M Garcia, J Giblin, M Glode, B Koontz, A Lowe, S Mitchell, J Mulhall, C Nelson, K Paich, C Saigal, T Skolarus, J Stanford, T Walsh, C E Pollack
BACKGROUND: Over half of men who receive treatment for prostate suffer from a range of sexual problems that affect negatively their sexual health, sexual intimacy with their partners and their quality of life. In clinical practice, however, care for the sexual side effects of treatment is often suboptimal or unavailable. The goal of the current study is to test a web-based intervention to support the recovery of sexual intimacy of prostate cancer survivors and their partners after treatment...
October 2, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28965787/reporting-erectile-function-outcomes-after-radiation-therapy-for-prostate-cancer-challenges-in-data-interpretation
#7
Ruud C Wortel, Luca Incrocci, John P Mulhall
BACKGROUND: Choice of prostate cancer treatment is frequently influenced by the expected chance of treatment-induced side effects such as erectile dysfunction (ED). However, great discrepancy in cited ED rates exists in the contemporary radiation therapy literature. AIM: To analyze the reported ED rates and cause of discrepancies and explore the strengths and limitations in the literature on radiation-induced ED. METHODS: We performed a PubMed literature search and reviewed the literature on ED rates associated with external-beam radiotherapy and brachytherapy from the past 10 years...
October 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28965272/predictors-of-the-quality-of-life-in-chinese-breast-cancer-survivors
#8
Juan Xia, Zheng Tang, Qinglong Deng, Renren Yang, Jiwei Wang, Jinming Yu
PURPOSE: Little is known about the importance of various factors which impair the quality of life (QOL) in survivors of breast cancer 1 year after diagnosis and over 1 year after diagnosis in China. Hence, the goal of this article is to quantitatively evaluate the factors which play an active role in impairing QOL 1 year after diagnosis and over 1 year after diagnosing survivors. METHODS: A population-based cross-sectional study was conducted at 34 Cancer Recovery Clubs across China from May 2014 to January 2015...
September 30, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28964809/continuous-soy-isoflavones-exposure-from-weaning-to-maturity-induces-downregulation-of-ovarian-steroidogenic-factor-1-gene-expression-and-corresponding-changes-in-dna-methylation-pattern
#9
Wenxiang Wang, Yan Sun, Yiwei Guo, Ping Cai, Yuchen Li, Jin Liu, Guoxi Cai, Aoyagi Kiyoshi, Wenchang Zhang
Female Wistar rats were treated with orally administered soy isoflavones at concentrations of 0, 25, 50, or 100mg/kg body weight from weaning until sexual maturity (3 mo.), and ovarian steroidogenesis was evaluated. After soy isoflavones were administered, a significant (P<0.05) decrease (44%) in the serum estrodial levels of the high-dose (HD) group were observed. Cultured granulosa cells from the middle- (MD) and HD groups showed significantly (P<0.05) reduced (31%, 45%, respectively) in vitro estradiol secretion, and those from the HD group showed significantly (P<0...
September 27, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28962900/effects-of-tamoxifen-on-neuronal-morphology-connectivity-and-biochemistry-of-hypothalamic-ventromedial-neurons-impact-on-the-modulators-of-sexual-behavior
#10
Susana I Sá, Natércia Teixeira, Bruno M Fonseca
Tamoxifen (TAM) is a selective estrogen receptor modulator, widely used in the treatment and prevention of estrogen-dependent breast cancer. Although with great clinical results, women on TAM therapy still report several side effects, such as sexual dysfunction, which impairs quality of life. The anatomo-functional substrates of the human sexual behavior are still unknown; however, these same substrates are very well characterized in the rodent female sexual behavior, which has advantage of being a very simple reflexive response, dependent on the activation of estrogen receptors (ERs) in the ventrolateral division of the hypothalamic ventromedial nucleus (VMNvl)...
September 28, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/28962668/tailor-tapered-discontinuation-versus-maintenance-therapy-of-antipsychotic-medication-in-patients-with-newly-diagnosed-schizophrenia-or-persistent-delusional-disorder-in-remission-of-psychotic-symptoms-study-protocol-for-a-randomized-clinical-trial
#11
Anne Emilie Stürup, Heidi Dorthe Jensen, Signe Dolmer, Merete Birk, Nikolai Albert, Mai Nielsen, Carsten Hjorthøj, Lene Eplov, Bjørn H Ebdrup, Ole Mors, Merete Nordentoft
BACKGROUND: The aim of the TAILOR trial is to investigate the effect of closely monitored tapering/discontinuation versus maintenance therapy with antipsychotic medication in patients with newly diagnosed schizophrenia or persistent delusional disorder and with minimum 3 months' remission of psychotic symptoms. METHODS AND DESIGN: Two hundred and fifty patients will be included from the psychiatric early intervention program, OPUS, in two regions in Denmark. Inclusion criteria are: ICD-10 diagnoses schizophrenia (F20, except F20...
September 29, 2017: Trials
https://www.readbyqxmd.com/read/28960583/communication-of-healthcare-professionals-is-there-ageism
#12
S Schroyen, S Adam, M Marquet, G Jerusalem, S Thiel, A-L Giraudet, P Missotten
Elderspeak is often used when talking to older individuals and is characterised by a slower and/or louder speech, a patronising tone, etc. A part of the reason of such communication can be found in the actual context of negative view of ageing. However, the link between view of ageing and elderspeak has never been objectively studied in oncology. Therefore, 40 healthcare professionals (physicians and medical students) record a podcast where they have to explain an endocrine therapy to two fictional patients (40- vs...
September 27, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28959063/quality-of-life-sexuality-anatomical-results-and-side-effects-of-implantation-of-an-alloplastic-mesh-for-cystocele-correction-at-follow-up-after-36-months
#13
Christian Fünfgeld, Margit Stehle, Brigit Henne, Jan Kaufhold, Dirk Watermann, Markus Grebe, Mathias Mengel
INTRODUCTION: Pelvic organ prolapse can significantly reduce quality of life of affected women, with many cases requiring corrective surgery. The rate of recurrence is relatively high after conventional prolapse surgery. In recent years, alloplastic meshes have increasingly been implanted to stabilize the pelvic floor, which has led to considerable improvement of anatomical results. But the potential for mesh-induced risks has led to a controversial discussion on the use of surgical meshes in urogynecology...
September 2017: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/28944458/goldspotted-spinefoot-siganus-punctatus-siganidae-age-based-reproductive-life-history-and-fisheries-vulnerability
#14
K Rhodes, D Hernandez-Ortiz, M Ioanis, W Washington, S Maxim, K Olpet, S Malakai
Between February 2015 and 2016, samples of the Indo-Pacific goldspotted spinefoot Siganus punctatus were taken from local fish markets, feeding sites and nursery grounds on the main island of Pohnpei, Micronesia, to ascertain sexual pattern, reproductive seasonality, age, growth and mortality. Microscopic examinations of gonads identified two seasonal peaks in reproduction: February to May and September to December, with evidence of some spawning activity in most months. Ripe females were observed 4 days on either side of the new moon...
September 25, 2017: Journal of Fish Biology
https://www.readbyqxmd.com/read/28944223/enrollment-childbearing-motivations-and-intentions-of-couples-in-the-creighton-model-effectiveness-intentions-and-behaviors-assessment-ceiba-study
#15
Joseph B Stanford, Christina A Porucznik
CONTEXT: The Creighton Model FertilityCare(TM) System (CrM) is a standardized approach for educating women about the biomarkers of their fertility. Couples can use this information for timing intercourse during "fertile" or "infertile" days in order to try to conceive or to avoid pregnancy. OBJECTIVES: The study of Creighton Model Effectiveness, Intentions, and Behaviors Assessment (CEIBA) was conducted to assess fertility motivations, intentions, fertility-related sexual behaviors, and their impact on effectiveness to avoid and to conceive among new users of the CrM...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28943032/formaldehyde-inhibits-sexual-behavior-and-expression-of-steroidogenic-enzymes-in-the-testes-of-mice
#16
Zhi-Jun Zang, You-Qiang Fang, Su-Yun Ji, Yong Gao, Yuan-Qiang Zhu, Ting-Ting Xia, Mei-Hua Jiang, Ya-Nan Zhang
BACKGROUND: Formaldehyde, a ubiquitous environmental pollutant, is used extensively and has been proved to impair male reproduction in mammals. However, no trials have explored whether formaldehyde affects sexual function. AIM: To evaluate the effect of long-term formaldehyde exposure on sexual behavior and to investigate the potential mechanism. METHODS: Forty C57BL/6 male mice were randomly allocated to four equally sized groups. Mice were exposed to formaldehyde at a dose of 0 (control), 0...
September 21, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28939186/is-the-lateral-angle-of-the-internal-acoustic-canal-sexually-dimorphic-in-non-adults-an-investigation-by-routine-cranial-magnetic-resonance-imaging
#17
G O Afacan, T Onal, G Akansel, A S Arslan
The lateral angle of the internal acoustic canal is one of the measurements of petrous bone that has been previously studied for sex estimation, mostly in adults. We aimed at evaluating the effects of age, side, and sex on the lateral angle of the internal acoustic canal in pediatric patients. Pediatric routine cranial MRI studies were retrospectively investigated for this study. The lateral angle was measured on T2-weighted axial images when the anterior and posterior lips of the meatus and the cochlea were clearly visible on the same image...
September 8, 2017: Homo: Internationale Zeitschrift Für die Vergleichende Forschung Am Menschen
https://www.readbyqxmd.com/read/28921241/evaluating-the-efficacy-of-vaginal-dehydroepiandosterone-for-vaginal-symptoms-in-postmenopausal-cancer-survivors-ncctg-n10c1-alliance
#18
Debra L Barton, Jeff A Sloan, Lynne T Shuster, Paula Gill, Patricia Griffin, Kathleen Flynn, Shelby A Terstriep, Fauzia N Rana, Travis Dockter, Pamela J Atherton, Michaela Tsai, Keren Sturtz, Jacqueline M Lafky, Mike Riepl, Jacqueline Thielen, Charles L Loprinzi
BACKGROUND: Women with estrogen deficiencies can suffer from vaginal symptoms that negatively impact sexual health. This study evaluated vaginal dehydroepiandrosterone (DHEA) for alleviation of vaginal symptoms. METHODS: This three-arm randomized, controlled trial evaluated DHEA 3.25 mg and DHEA 6.5 mg, each compared to a plain moisturizer (PM) over 12 weeks, to improve the severity of vaginal dryness or dyspareunia, measured with an ordinal scale, and overall sexual health using the Female Sexual Function Index (FSFI)...
September 18, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28894392/fractional-co2-laser-treatment-for-vulvovaginal-atrophy-symptoms-and-vaginal-rejuvenation-in-perimenopausal-women
#19
César Arroyo
BACKGROUND: This study investigated a novel fractional carbon dioxide (CO2) laser for treatment of symptoms associated with vulvovaginal atrophy (VVA) in perimenopausal women. METHODS: The study included 21 perimenopausal women (mean age 45±7 years) treated three times by CO2 laser resurfacing and coagulation of the vaginal canal tissue and mucosal tissue of the introitus. Vaginal health index (VHI) scores were computed by the investigator at baseline and follow-ups...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28891846/quality-of-life-in-rectal-cancer-patients-after-chemoradiation-watch-and-wait-policy-versus-standard-resection-a-matched-controlled-study
#20
MULTICENTER STUDY
Britt J P Hupkens, Milou H Martens, Jan H Stoot, Maaike Berbee, Jarno Melenhorst, Regina G Beets-Tan, Geerard L Beets, Stéphanie O Breukink
BACKGROUND: Fifteen to twenty percent of patients with locally advanced rectal cancer have a clinical complete response after chemoradiation therapy. These patients can be offered nonoperative organ-preserving treatment, the so-called watch-and-wait policy. The main goal of this watch-and-wait policy is an anticipated improved quality of life and functional outcome in comparison with a total mesorectal excision, while maintaining a good oncological outcome. OBJECTIVE: The aim of this study was to compare the quality of life of watch-and-wait patients with a matched-controlled group of patients who underwent chemoradiation and surgery (total mesorectal excision group)...
October 2017: Diseases of the Colon and Rectum
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