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Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: An Update Roni P. Dodiuk-Gad, Wen-Hung Chung, Laurence Valeyrie-Allanore, Neil H. Shear

Roni P Dodiuk-Gad, Wen-Hung Chung, Laurence Valeyrie-Allanore, Neil H Shear
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening mucocutaneous reactions, predominantly drug induced. The mortality rates for SJS and TEN are as high as 30 %, and short- and long-term morbidities are very common. SJS/TEN is one of the few dermatological diseases that constitute a true medical emergency. Early recognition and prompt and appropriate management can be lifesaving. In recent years, our understanding of the pathogenesis, clinical presentation, and management of SJS/TEN has improved...
December 2015: American Journal of Clinical Dermatology
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