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https://www.readbyqxmd.com/read/29352843/tocilizumab-after-a-first-line-with-anti-tnf-in-rheumatoid-arthritis-a-cost-consequence-analysis-in-the-italian-setting
#1
Sergio Iannazzo, Maurizio Benucci, Ennio Giulio Favalli
OBJECTIVES: Switching to a different mechanism of action in rheumatoid arthritis (RA) patients after a first anti-TNF-α has proved to be effective. The objective of this study was a health economic assessment in Italy. METHODS: The study was conducted using a pharmacoeconomic model with a 3-year time horizon. Effectiveness was measured as days gained in low disease activity (LDA; DAS28-ESR <3.2) or in remission (DAS28-ESR <2.6). The model simulated the response to treatments, based on the Rotation Or Change (ROC) trial, the probability of discontinuation and switch to a 3rd-line biologic, and the transition to death...
January 15, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29328797/does-a-dedicated-orthopaedic-day-surgery-list-improve-delivery-of-trauma-services
#2
Jagmeet Singh Bhamra, Baljinder S Dhinsa, Sohil Patel, Chi Davies, Matthew OLiver
Our aim was to implement a 23-hour pathway for uncomplicated trauma to overcome delays and improve efficiency. A retrospective review of a single surgeon series of 105 consecutive patients operated on between July 2010 and July 2011 was performed. With recently revised trauma tariffs, we believe an efficient day surgery trauma list improves theatre utilisation, reduces inpatient bed demands, prioritises major and sub-specialist trauma and delivers patient satisfaction.
November 2017: Journal of Perioperative Practice
https://www.readbyqxmd.com/read/29321017/influence-of-the-child-s-perceived-general-health-on-the-primary-caregiver-s-health-status
#3
Janine Verstraete, Lebogang Ramma, Jennifer Jelsma
BACKGROUND: In estimating the impact of an intervention, ignoring the effect of improving the health of one member of the caregiver/child dyad on the Health Related Quality of Life (HRQoL) of the other member may lead to an underestimation of the utility gained. This may be particularly true for infants/young children and their caregivers. The aim of this study was to quantify the interaction between the child's perceived general health as assessed by the newly developed Toddler and Infant Questionnaire (TANDI) on the reporting of the caregiver's own HRQoL as assessed by the EQ-5D-3 L...
January 10, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29320495/the-who-2016-verbal-autopsy-instrument-an-international-standard-suitable-for-automated-analysis-by-interva-insilicova-and-tariff-2-0
#4
Erin K Nichols, Peter Byass, Daniel Chandramohan, Samuel J Clark, Abraham D Flaxman, Robert Jakob, Jordana Leitao, Nicolas Maire, Chalapati Rao, Ian Riley, Philip W Setel
BACKGROUND: Verbal autopsy (VA) is a practical method for determining probable causes of death at the population level in places where systems for medical certification of cause of death are weak. VA methods suitable for use in routine settings, such as civil registration and vital statistics (CRVS) systems, have developed rapidly in the last decade. These developments have been part of a growing global momentum to strengthen CRVS systems in low-income countries. With this momentum have come pressure for continued research and development of VA methods and the need for a single standard VA instrument on which multiple automated diagnostic methods can be developed...
January 2018: PLoS Medicine
https://www.readbyqxmd.com/read/29317109/the-role-of-the-2011-patients-rights-in-cross-border-health-care-directive-in-shaping-seven-national-health-systems-looking-beyond-patient-mobility
#5
Natasha Azzopardi-Muscat, Rita Baeten, Timo Clemens, Triin Habicht, Ilmo Keskimäki, Iwona Kowalska-Bobko, Anna Sagan, Ewout van Ginneken
Reports on the implementation of the Directive on the application of Patients' Rights in Cross-border Healthcare indicate that it had little impact on the numbers of patients seeking care abroad. We set out to explore the effects of this directive on health systems in seven EU Member States. Key informants in Belgium, Estonia, Finland, Germany, Malta, Poland and The Netherlands filled out a structured questionnaire. Findings indicate that the impact of the directive varied between countries and was smaller in countries where a large degree of adaptation had already taken place in response to the European Court of Justice Rulings...
January 4, 2018: Health Policy
https://www.readbyqxmd.com/read/29316832/cost-effectiveness-of-supported-employment-adapted-for-people-with-affective-disorders
#6
Sanjib Saha, Ulrika Bejerholm, Ulf-G Gerdtham, Johan Jarl
OBJECTIVE: The individual enabling and support (IES) model was effective in gaining competitive employment for people with affective disorders compared with traditional vocational rehabilitation (TVR) services in a randomized controlled trial in a Swedish setting. The object of this study is to perform a cost-effectiveness analysis of IES comparing to TVR. METHODS: We considered the costs of intervention and productivity gain due to increased competitive employment...
January 9, 2018: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/29307067/benchmarking-the-efficiency-of-the-chilean-water-and-sewerage-companies-a-double-bootstrap-approach
#7
María Molinos-Senante, Guillermo Donoso, Ramon Sala-Garrido, Andrés Villegas
Benchmarking the efficiency of water companies is essential to set water tariffs and to promote their sustainability. In doing so, most of the previous studies have applied conventional data envelopment analysis (DEA) models. However, it is a deterministic method that does not allow to identify environmental factors influencing efficiency scores. To overcome this limitation, this paper evaluates the efficiency of a sample of Chilean water and sewerage companies applying a double-bootstrap DEA model. Results evidenced that the ranking of water and sewerage companies changes notably whether efficiency scores are computed applying conventional or double-bootstrap DEA models...
January 6, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29304940/eq-5d-5l-versus-eq-5d-3l-the-impact-on-cost-effectiveness-in-the-united-kingdom
#8
Monica Hernandez Alava, Allan Wailoo, Sabine Grimm, Stephen Pudney, Manuel Gomes, Zia Sadique, David Meads, John O'Dwyer, Garry Barton, Lisa Irvine
OBJECTIVES: To model the relationship between the three-level (3L) and the five-level (5L) EuroQol five-dimensional questionnaire and examine how differences have an impact on cost effectiveness in case studies. METHODS: We used two data sets that included the 3L and 5L versions from the same respondents. The EuroQol Group data set (n = 3551) included patients with different diseases and a healthy cohort. The National Data Bank data set included patients with rheumatoid disease (n = 5205)...
January 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/29288173/population-level-impact-of-diabetes-integrated-care-on-commissioner-payments-for-inpatient-care-among-people-with-type-2-diabetes-in-cambridgeshire-a-postintervention-cohort-follow-up-study
#9
Dahai Yu, Wei Yang, Yamei Cai, Zhanzheng Zhao, David Simmons
OBJECTIVES: Few studies have estimated the effect of diabetes integrated care at a population level. We have assessed the impact of introducing a community service-led diabetes integrated care programme on commissioner payments (tariff) for inpatient care in rural England. METHODS: The Diabetes Integrated Care Initiative was delivered by a separate enhanced community diabetes service, increasing specialist nursing, dietetic, podiatry and medical support to primary care and patients, while linking into other diabetes specialist services...
December 28, 2017: BMJ Open
https://www.readbyqxmd.com/read/29258167/small-water-enterprise-in-rural-rwanda-business-development-and-year-one-performance-evaluation-of-nine-water-kiosks-at-health-care-facilities
#10
Alexandra Huttinger, Laura Brunson, Christine L Moe, Kristin Roha, Providence Ngirimpuhwe, Leodomir Mfura, Felix Kayigamba, Philbert Ciza, Robert Dreibelbis
Small water enterprises (SWEs) have lower capital expenditures than centralized systems, offering decentralized solutions for rural markets. This study evaluated SWEs in rural Rwanda, where nine health care facilities (HCF) owned and operated water kiosks supplying water from onsite water treatment systems (WTS). SWEs were monitored for 12 months. Spearman's Rank Correlation Coefficient (rs) was used to evaluate correlations between demand for kiosk water and community characteristics, and between kiosk profit and factors influencing the cost model...
December 16, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29231047/cost-effectiveness-analysis-of-treatments-involving-radioembolization-in-intermediate-stage-hepatocellular-carcinoma
#11
Carla Rognoni, Oriana Ciani, Silvia Sommariva, Rosanna Tarricone
AIM: We evaluated two treatment sequences, transarterial radioembolization followed by transarterial chemoembolization and possibly sorafenib (=TTS) versus transarterial radioembolization followed by sorafenib alone (=TS), to identify the most cost-effective pathway to treat intermediate-stage hepatocellular carcinoma from the Italian healthcare system perspective. MATERIALS & METHODS: A Markov model was developed to project costs and health outcomes for TTS and TS over a lifetime horizon...
December 12, 2017: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29206159/energy-management-in-smart-cities-based-on-internet-of-things-peak-demand-reduction-and-energy-savings
#12
Chinmaya Mahapatra, Akshaya Kumar Moharana, Victor C M Leung
Around the globe, innovation with integrating information and communication technologies (ICT) with physical infrastructure is a top priority for governments in pursuing smart, green living to improve energy efficiency, protect the environment, improve the quality of life, and bolster economy competitiveness. Cities today faces multifarious challenges, among which energy efficiency of homes and residential dwellings is a key requirement. Achieving it successfully with the help of intelligent sensors and contextual systems would help build smart cities of the future...
December 5, 2017: Sensors
https://www.readbyqxmd.com/read/29201288/cost-effectiveness-analysis-of-ibrutinib-in-patients-with-waldenstr%C3%A3-m-macroglobulinemia-in-italy
#13
Andrea Aiello, Anna D'Ausilio, Roberta Lo Muto, Francesca Randon, Luca Laurenti
Background and Objective: Ibrutinib has recently been approved in Europe for Waldenström Macroglobulinemia (WM) in symptomatic patients who have received at least one prior therapy, or in first-line treatment for patients unsuitable for chemo-immunotherapy. The aim of the study is to estimate the incremental cost-effectiveness ratio (ICER) of ibrutinib in relapse/refractory WM, compared with the Italian current therapeutic pathways (CTP). Methods: A Markov model was adapted for Italy considering the National Health System perspective...
2017: Journal of Market Access & Health Policy
https://www.readbyqxmd.com/read/29200879/cost-consequence-analysis-of-sitagliptin-versus-sulfonylureas-as-add-on-therapy-for-the-treatment-of-diabetic-patients-in-italy
#14
Valentina Lorenzoni, Fabio Baccetti, Stefano Genovese, Enrico Torre, Giuseppe Turchetti
Objective: Diabetes mellitus is a chronic disease related to a significant impact in both epidemiologic and economic terms. In Italy, around 3.6 million people are affected by diabetes and this number is expected to increase significantly in the next few years. As recommended by current national and international guidelines, metformin (Met) is prescribed as first-line pharmacological treatment, and many pharmacological alternatives are available for patients uncontrolled with Met monotherapy...
2017: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/29200010/role-of-systematic-lymphadenectomy-to-tailor-adjuvant-therapy-in-early-endometrial-cancer
#15
Vivek Nama, Amit Patel, Lisa Kirk, John Murdoch, Joanne Bailey
OBJECTIVE: The long-standing protocol at our center for apparent stage I and II endometrial cancers comprises hysterectomy and bilateral salpingo-oophorectomy without lymphad-enectomy. Adjuvant treatment is based in line with Postoperative Radiation Therapy in Endometrial Carcinoma 1 protocol. Our aim was to quantify the number of patients who would avoid external beam radiation therapy (EBRT) in our institution if we adopted a protocol of lymphadenectomy to tailor adjuvant EBRT and its impact on cost and quality of life...
December 1, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29175097/cost-effectiveness-of-paclitaxel-ramucirumab-combination-therapy-for-advanced-gastric-cancer-progressing-after-first-line-chemotherapy-in-japan
#16
Shota Saito, Yusuke Muneoka, Takashi Ishikawa, Kouhei Akazawa
PURPOSE: The combination of paclitaxel + ramucirumab is a standard second-line treatment in patients with advanced gastric cancer. This therapy has been associated with increased median overall survival and progression-free survival compared with those with paclitaxel monotherapy. We evaluated the cost-effectiveness of paclitaxel + ramucirumab combination therapy in patients with advanced gastric cancer, from the perspective of health care payers in Japan. METHODS: We constructed a Markov model to compare, over a time horizon of 3 years, the costs and effectiveness of the combination of paclitaxel + ramucirumab and paclitaxel alone as second-line therapies for advanced gastric cancer in Japan...
November 23, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/29163281/academic-self-efficacy-partially-mediates-the-relationship-between-scottish-index-of-multiple-deprivation-and-composite-attainment-score
#17
John L Perry, Martin Dempster, Michael T McKay
A developing literature continues to testify to the relationship between higher socio-economic status (SES) and better academic attainment. However, the literature is complex in terms of the variety of SES and attainment indicators used. Against the backdrop of a Scottish Government initiative to close the attainment gap between higher and lower SES children, the present study examined the relationship between individual-level Scottish Index of Multiple Deprivation (SIMD) and National Lower Tariff Score in school children in the West of Scotland...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29157876/evaluating-the-effect-of-tariff-on-wastage-and-return-of-blood-products-in-kerman-province
#18
H Anani, I Baluchi, M Ghazizadeh, H Mardani Valandani, R Mirzaee Khalilabadi
BACKGROUND: In Iran blood products had been available to health care centers on free order to reduce the wastage they were tariffed in 2016. Thus, health care centers must pay for the blood products and take back the payment from the insurance. The aim of this study was to examine the effects of the tariff on consumption, wastage and return rates of blood products in health care centers in Kerman province. MATERIALS AND METHODS: In this retrospective cross-sectional study, demand, delivery and return rates of blood products (fresh frozen plasma, red blood cell and platelet) were examined in 23 health care centers and hospitals before and after the tariff...
November 17, 2017: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/29156027/why-has-nhs-england-introduced-an-innovation-and-technology-tariff-to-improve-safer-arterial-systems-in-england
#19
S Thillainathan, M Z Mariyaselvam
No abstract text is available yet for this article.
December 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29154005/levers-supporting-tariff-growth-for-water-services-evidence-from-a-contingent-valuation-analysis
#20
Andrea Guerrini, Vania Vigolo, Giulia Romano, Federico Testa
The backwardness of the water utilities sector necessitates urgent investment in infrastructure to improve water quality and efficiency in water supply networks. A policy of tariff growth represents the main source to sustain such investments. Therefore, customer engagement in the form of willingness to pay (WTP) is highly desirable by water utilities to obtain social legitimization and support. This study examines the determinants of consumers' WTP for improvement programs for three drinking water issues: quality of water sources, renewal of water mains, and building of new wastewater treatment plants...
November 15, 2017: Journal of Environmental Management
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