M Cathelin, R Vignes, A Malki, P Viars
For the purposes of this study, sulfentanil is administered to conscious men in increasing doses (0,00015, 0,0003, 0,0006 mg/kg) by intra-muscular injection, and the results are compared with those obtained in the same condition by administration of morphine (0,100, 0,150, 0,200 mg/kg). The administration of both drugs provokes the same side-effects. The failure of the breathing rate is as fast as observed following the administration of morphine in equi-analgesic doses. As in the case of analgesia, the time taken for the falling off of the breathing rate to occur, and its duration are shorter with sulfentanil, than with morphine...
1981: Anesthésie, Analgésie, Réanimation