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H T Sun, M Xu, G L Chen, J He
Objective: This study aimed to compare dexmedetomidine with remifentanil for conscious sedation in patients undergoing radiofrequency ablation of hepatocellular carcinoma. Methods: Sixty patients, who were aged 41 to 73 years with American Society of Anesthesiologists (ASA) physical status Ⅰ-Ⅱ, and scheduled for elective radiofrequency ablation of hepatocellular carcinoma under conscious sedation in National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, from January 2014 to June 2016, were allocated randomly to receive dexmedetomidine maintenance regimen(group D, n =30)or remifentanil maintenance regimen(group R, n =30)by random digital table...
February 27, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
H T Sun, M Xu, G L Chen, J He
Objective: To investigate the effects of remifentanil infusion on emergence and recovery characteristics of patients with thoracoscopic lobectomy following general anaesthesia with sevoflurane. Methods: One hundred patients, who were aged 37 to 65 years with American Society of Anesthesiologists (ASA) physical status 1-2, and scheduled for elective thoracoscopic lobectomy under general anaesthesia in National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, from February 2016 to August 2016, were allocated to receive sevoflurane maintenance regimen(group S, n =50)or sevoflurane/remifentanil maintenance regimen(group SR, n =50)by random digital table...
November 28, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Hang Shi, Duo Yang, Jie Liu
BACKGROUND AND AIM: Deep sedation without intubation for termination of first trimester pregnancy of suction evacuation entails use of sedatives such as propofol or a combination of propofol and sulfentanil, with unwanted complications. Dexmedetomidine is an α2 -adrenoreceptor agonist which provides sedation, anxiolysis and analgesia, without any of the complications associated with the popular sedatives. METHODS: A total number of 90 patients were randomized to three groups: 1...
September 24, 2017: Asian Journal of Anesthesiology
Xin-liang Meng, Qiang Qu
OBJECTIVE: To observe the effect of acupoint injection of Lidocaine on serum IL-1β, TNF-α and T-lymphocyte subset activities in patients undergoing laparoscopic cholecystectomy (LC), so as to reveal its mechanisms underlying relieving postoperative pain and potentiating rehabilitation. METHODS: Eighty patients scheduled for elective LC surgery (grade I or II, according to American Standards of Association, ASA) were randomly divided into four groups, namely intravenous analgesia (IVA) , right forearm-injection (forearm-), Jiaji (EX-B 2, Thorax 8)-injection (EX-B 2-1), and Zusanli-injection (ST 36-1), with 20 patients in each group...
February 2016: Zhen Ci Yan Jiu, Acupuncture Research
Jing-yi Li, Ren Liao
BACKGROUND: Catheter-related bladder discomfort (CRBD) is common in male patients under general anesthesia, and it may cause patient agitation and exacerbated postoperative pain. In this study, we will enroll male patients undergoing elective surgery with urinary catheterization after anesthetic induction and compare the efficacy of a dorsal penile nerve block (DPNB) and intravenous tramadol for the prevention of CRBD. METHODS/DESIGN: This trial is a prospective, open-label, randomized controlled trial that will test the superiority of a dorsal penile nerve block with 0...
December 30, 2015: Trials
Min Qiu, Ya-nan Zong, Jian Lu, Lu-lin Ma, Qing Zheng, Xiang-yang Guo
Anaphylaxis is an acute and fatal systemic allergic reaction to an allergen, and it could be an unpredictable and life-threatening cause during anesthesia. The main purpose of this paper is to report a case of anaphylactic shock during the anesthesia induction and to review the prophylaxis and treatment of anaphylactic reactions and anaphylactoid reactions during the anesthesia period. A 63-year-old man, with a mass on his adrenal, was scheduled to a laparoscopic adrenal tumor excision. During the anesthesia induction period, after administrated sulfentanil, propofol and rocuronium, the blood pressure was decreased and the heart rate was increased...
October 18, 2015: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
Peng Liang, Cheng Zhou, Kai-Yu Li, Li-Juan Guo, Bin Liu, Jin Liu
OBJECTIVE: It is controversial that whether the GABA receptors contribute to the hypnotic action of volatile anesthetics. This study was to detect the effect of GABA receptors on the hypnotic action of volatile anesthetics by evaluation of the effect of intravenous flumazenil on sevoflurane minimum alveolar anesthetic concentration-awake (MAC-Awake) and emergence mental status. METHODS: This study included two steps. Firstly, 49 healthy patients, aged 20-40 years scheduled for elective surgeries, were randomly assigned to two groups, a flumazenil group (n=24) and a saline group (n=25)...
2014: International Journal of Clinical and Experimental Medicine
JunLe Liu, WeiXiu Yuan, XiaoLin Wang, Colin F Royse, MaoWei Gong, Ying Zhao, Hong Zhang
BACKGROUND: Both peripheral nerve blocks with sedation or general anesthesia can be used for total knee replacement surgery. OBJECTIVES: We compared these anesthetic techniques on the postoperative quality of recovery early in elderly patients. MATERIALS AND METHODS: In our study, 213 patients who were ≥65 years old and undergoing total knee replacement were randomized to peripheral nerve blocks (PNBs) - lumbar plexus and sciatic - with propofol sedation, or general anesthesia with combined propofol and remifentanil...
2014: Clinical Interventions in Aging
Yichun Wang, Qulian Guo, Mingde Wang, E Wang, Wangyuan Zou, Jianghong Zhao
OBJECTIVE: To investigate the effect of intrathecal sufentanil and protein kinase C inhibitor on pain threshold and the expression of N-methyl-D-aspartate receaptors (NMDAR)/calcitonin generelated peptide (CGRP) in spinal dorsal horn in rats with neuropathic pain. METHODS: Fifty-four healthy male Sprague-Dawley rats were randomly divided into 6 groups (9 in each group). The rats in the sham group(Group S) + spared nerve injury (SNI), SP+SNI, and P+SNI were intrathecally injected sufentanil (1 μg), sufentanil (1 μg) and chelerythrine chloride (11 μg), chelerythrine chloride (11 μg) followed by 10 μL normal saline once every day for 14 days postoperatively, respectively...
August 2012: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
Pei-rong Lin, Xiu-shu Luan, Dong-ya Zhang, Qing-yu Wu
OBJECTIVE: To summarize the experience in anesthetic management for correction of Ebstein's anomaly. METHODS: A total of 79 patients with Ebstein's anomaly who underwent surgical repair in our hospital during the time from March 2004 to September 2010 were retrospectively summarized for their anesthetic management. Anesthesia was done for the patients undergoing correction of Ebstein's anomaly. The adults patients were premedicated with intramuscular morphine 0...
May 8, 2012: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Bo Xu, Zhi-ping Wang, Yan-juan Wang, Yi-ping Hu, Li-jun Wang, Xiao-hai Wang
OBJECTIVE: To observe the effects of short-term exposure to opioid analgesics on human sperm motility. METHODS: Twenty normal semen samples were collected, each divided into 19 groups, one as the control and the others treated in vitro with six opioid analgesics at three different concentrations, respectively, and sperm motility was assessed by computer-assisted sperm analysis at 15 min, 2 h and 4 h. RESULTS: Compared with the control group, fentanyl, alfentanil and sufentanil at 1 x 10(-5), 2 x 10(-3) and 0...
January 2012: Zhonghua Nan Ke Xue, National Journal of Andrology
Torsten Kluba, Fabian Hofmann, Sabine Bredanger, Gunnar Blumenstock, Thomas Niemeyer
This prospective study aimed to compare the efficacy of epidural (EDA) versus intravenous (PCA) application of analgesics after lumbar fusion. Fifty-two patients scheduled for elective posterior instrumented lumbar fusion were randomized into two groups. EDA patients received an epidural catheter intraoperatively, and administration of ropivacain and sulfentanil was started after a normal postoperative wake-up test in the recovery room area. PCA patients received intravenous opioids in the post-operative period...
March 20, 2010: Orthopedic Reviews
Hui-Qing Xu, Jian-Min Xing, Ruo Jia
OBJECTIVE: To observe the effects and side effects of Pentazocine for postoperative intravenous analgesia in patients with lumbar herniation, and to investigate the difference of Pentazocine with different doses. METHODS: From January 2009 to December 2009, sixty patients undergone laminectomy and pedicle internal fixation, who using equal analgesic dosage of Pentazocine and Sulfentanil, were retrospectively analysed. The patients including 34 males and 26 females, aged 40 to 65 (average 59), weighted 60 to 80 kg (average 71 kg), ASA I-II, were divided into Sufentanil group and Pentazocine group I and Pentazocine group II, with 20 cases each...
November 2010: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
Yigal Leykin, Massimiliano Dalsasso, Tomasso Setti, Tommaso Pellis
STUDY OBJECTIVE: To determine whether low-dose ephedrine plus priming with low-dose cisatracurium improves intubating conditions. DESIGN: Prospective, randomized, double-blinded study. SETTING: Operating room. PATIENTS: 124 ASA physical status I and II patients scheduled for elective surgery. INTERVENTIONS: Patients were randomly assigned to 4 groups (n = 31): Group PE (priming + ephedrine), Group P (priming), Group E (ephedrine), and Group NPE (no priming, no ephedrine)...
September 2010: Journal of Clinical Anesthesia
Miao-ning Gu, Meng Wang, Zai-sheng Qin, Jin-fang Xiao, Jian-jun Tang, Jian-she Xu
OBJECTIVE: To define the ideal time window for intubation after rocuronium administration during target-controlled infusion (TCI) ofpropofol and sulfentanil. METHODS: One hundred and twenty elective surgical patients (age range 18-55 years) were randomized into 4 groups (n=30) according to the intubation time after administration of the muscle relaxant. Patients with predicted difficult airway were excluded. General anesthesia was induced by TCI of propofol and sulfentanil...
May 2007: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
S Alayurt, D Memis, Z Pamukcu
This study was designed to evaluate the effect of sufentanil, tramadol or clonidine added to lignocaine for intravenous regional anaesthesia. We investigated the onset and duration of sensory and motor block, the quality of the anaesthesia, intraoperative and postoperative haemodynamics, intraoperative and postoperative pain and sedation. Sixty patients undergoing ambulatory hand surgery received intravenous regional anaesthesia using 35 ml of 0.5% lignocaine and either 5 ml saline (Group L, n = 15); sufentanil 25 micrograms (Group LS, n = 15); tramadol 100 mg (Group LT, n = 15) or clonidine 1 microgram...
February 2004: Anaesthesia and Intensive Care
A T Sia, J L Chong, J W Chiu
UNLABELLED: This controlled, double-blinded, prospective trial of 42 parturients in early labor was conducted to determine whether halving the total amount of intrathecal (i.t.) sufentanil and bupivacaine reduced the incidence of systemic hypotension while providing adequate analgesia with minimal lower limb motor block. Combined spinal-epidural analgesia (CSE) was instituted; Group A (n = 21) received a total of 10 microg of sulfentanil plus 2.5 mg of bupivacaine, whereas Group B (n = 21) received half that dose...
February 1999: Anesthesia and Analgesia
S de Lange, M J Boscoe, T H Stanley, N de Bruijin, D M Philbin, C H Coggins
Antidiuretic hormone (ADH), growth hormone (GH), and cardiovascular responses to large (anesthetic) doses of alfentanil (1.2 +/- 0.02 mg/kg) and oxygen and sufentanil (13.1 +/- 0.4 microgram/kg) and oxygen were measured before and during surgery (including cardiopulmonary bypass) and at the end of surgery in 29 patients undergoing coronary artery bypass surgery. The data demonstrate that alfentanil-O2 and sufentanil-O2 result in little change in cardiovascular dynamics throughout anesthesia and surgery, and also prevent changes in plasma levels of ADH and GH at all times during the study...
May 1982: Anesthesia and Analgesia
M Cathelin, R Vignes, A Malki, P Viars
For the purposes of this study, sulfentanil is administered to conscious men in increasing doses (0,00015, 0,0003, 0,0006 mg/kg) by intra-muscular injection, and the results are compared with those obtained in the same condition by administration of morphine (0,100, 0,150, 0,200 mg/kg). The administration of both drugs provokes the same side-effects. The failure of the breathing rate is as fast as observed following the administration of morphine in equi-analgesic doses. As in the case of analgesia, the time taken for the falling off of the breathing rate to occur, and its duration are shorter with sulfentanil, than with morphine...
1981: Anesthésie, Analgésie, Réanimation
M Cathelin, R Vignes, A Malki, P Viars
In the case of a conscious man suffering from a painful injury in the facial and trigeminal nerves, the administration of intra-muscular injections of increasing doses of morphine and sulfentanil provokes constant analgesia in direct proportion to the administered dose. The admitted dosages for each product are as follows. M = 0,100, 0,150, 0,200 mg/kg S = 0,00015, 0,0003, 0,0006 mg/kg. Sulfentanil is a highly active analgesic whose activity is about 333 times greater than that of morphine and 13 times greater than that of fentanyl...
1981: Anesthésie, Analgésie, Réanimation
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