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Miguel Hernaez, Carlos R Zamarreño, Sonia Melendi-Espina, Liam R Bird, Andrew G Mayes, Francisco J Arregui
Graphene and its derivatives have become the most explored materials since Novoselov and Geim (Nobel Prize winners for Physics in 2010) achieved its isolation in 2004. The exceptional properties of graphene have attracted the attention of the scientific community from different research fields, generating high impact not only in scientific journals, but also in general-interest newspapers. Optical fibre sensing is one of the many fields that can benefit from the use of these new materials, combining the amazing morphological, chemical, optical and electrical features of graphene with the advantages that optical fibre offers over other sensing strategies...
January 14, 2017: Sensors
Tyson J Olds, George R Kracke
No abstract text is available yet for this article.
February 2017: Anesthesiology
Sharon A Tooze, Lisa A Hannan, Michael S Marks, Tom H Stevens, Trina A Schroer
No abstract text is available yet for this article.
January 17, 2017: Traffic
Jonathan C Barnes, Chad A Mirkin
No abstract text is available yet for this article.
January 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
Michael E Fisher, Naoto Nagaosa
No abstract text is available yet for this article.
January 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
Salvador Navarro Colás
No abstract text is available yet for this article.
January 13, 2017: Gastroenterología y Hepatología
Chris Toumey
No abstract text is available yet for this article.
January 10, 2017: Nature Nanotechnology
Franco Peracchi
No abstract text is available yet for this article.
November 30, 2016: Economics and Human Biology
E El Haddad, A B Giannì, G E Mancini, F Cura, F Carinci
PURPOSE: The aim of our study is to value the microbial contamination in the implant-abutment connections (IAC) of a Nobel Replace Conical Connection implant system [Nobel Biocare®, Vimercate (MB), Italy]. MATERIALS AND METHODS: To identify the capability of the implant to protect the internal space from the external environment, the passage of genetically modified bacteria across IAC was evaluated. Four Nobel Replace Conical Connection implants (Nobel Biocare®, Vimercate (MB), Italy) were immerged in a bacterial culture for twenty-four hours and then bacteria amount was measured inside and outside IAC with Real-time PCR...
April 2016: Oral & Implantology
Beth Levine, Daniel J Klionsky
Autophagy is an ancient pathway in which parts of eukaryotic cells are self-digested within the lysosome or vacuole. This process has been studied for the past seven decades; however, we are only beginning to gain a molecular understanding of the key steps required for autophagy. Originally characterized as a hormonal and starvation response, we now know that autophagy has a much broader role in biology, including organellar remodeling, protein and organelle quality control, prevention of genotoxic stress, tumor suppression, pathogen elimination, regulation of immunity and inflammation, maternal DNA inheritance, metabolism, and cellular survival...
December 30, 2016: Proceedings of the National Academy of Sciences of the United States of America
K A Brokstad
No abstract text is available yet for this article.
December 2016: Scandinavian Journal of Immunology
Ramin Atash, Mohamed-Reda Boularbah, Cetik Sibel
PURPOSE: The aim of this work is to evaluate different types of materials used for making implant abutments, by means of an in vitro study and a review of the literature, in order to identify the indications for a better choice of an implant-supported restoration in the anterior section. MATERIALS AND METHODS: 5 implant abutments were tested in a random order in the superior anterior maxilla of pig gingiva (n = 8): titanium dioxide (Nobel Biocare); zirconium dioxide, Standard BO shade (Nobel Biocare, Kloten, Switzerland); zirconium dioxide, Light BI shade (Nobel Biocare); zirconium dioxide, Intense A 3...
December 2016: Journal of Advanced Prosthodontics
Nils Hansson, Matthis Krischel, Thorsten Halling, Friedrich Moll, Heiner Fangerau
PURPOSE: Recent historical research has reconstructed the roads leading to the Nobel Prize for the trained urologists Werner Forssmann (1904-1979) in 1956 and Charles Huggins (1901-1997) in 1966. However, the story of urology and the Nobel Prize does not start and end with the laureates. Taking James Israel (1848-1926), Félix Guyon (1831-1920), and Peter J Freyer (1852-1921) as examples, this paper shows that pioneers in urology were in fact runners-up for the award much earlier. METHODS: The study is based on an analysis of original files in the Nobel Prize archive in Stockholm, scientific publications of the early twentieth century, and secondary literature...
December 21, 2016: World Journal of Urology
Jeremy S Leventhal, Christina M Wyatt, Michael J Ross
This year, the Nobel Prize in Physiology or Medicine was awarded to Yoshinori Ohsumi for his groundbreaking work in dissecting the mechanisms of autophagy, a cellular process resulting in the organized degradation of cytoplasmic components. Ohsumi's work paved the way for subsequent studies that demonstrated critical roles for autophagy in modulating both acute and chronic kidney injury. This work may lead to future therapeutic approaches that target the autophagy system to prevent or treat kidney diseases...
January 2017: Kidney International
Claudia P Spampinato
The genome integrity of all organisms is constantly threatened by replication errors and DNA damage arising from endogenous and exogenous sources. Such base pair anomalies must be accurately repaired to prevent mutagenesis and/or lethality. Thus, it is not surprising that cells have evolved multiple and partially overlapping DNA repair pathways to correct specific types of DNA errors and lesions. Great progress in unraveling these repair mechanisms at the molecular level has been made by several talented researchers, among them Tomas Lindahl, Aziz Sancar, and Paul Modrich, all three Nobel laureates in Chemistry for 2015...
December 20, 2016: Cellular and Molecular Life Sciences: CMLS
George Fink
Hans Selye in a note to Nature in 1936 initiated the field of stress research by showing that rats exposed to nocuous stimuli responded by way of a "general adaptation syndrome" (GAS). One of the main features of the GAS was the "formation of acute erosions in the digestive tract, particularly in the stomach, small intestine and appendix". This provided experimental evidence for the view based on clinical data that gastro-duodenal (peptic) ulcers could be caused by stress. This hypothesis was challenged by Marshall and Warren's Nobel-prize (2005) winning discovery of a causal association between Helicobacter pylori and peptic ulcers...
December 20, 2016: Journal of Endocrinology
Kalyan B Bhattacharyya
Godfrey Hounsfield, a biomedical engineer contributed enormously towards the diagnosis of neurological and other disorders by virtue of his invention of the computed axial tomography scan for which he was awarded the Nobel Prize in 1979. Working for the Electrical and Musical Industry (EMI) Limited and in collaboration with two radiologists, James Ambrose and Louis Kreel, he introduced the use of this machine in 1971 at the Atkinson Morley's Hospital in Wimbledon. He continued to improve the quality of the devise and the human head was scanned for the first time in 1972...
October 2016: Annals of Indian Academy of Neurology
Krzysztof Rutkowski, Edyta Dembińska
The paper presents the post-war history of post-traumatic research conducted at the Department of Psychiatry of the Jagiellonian University and the analysis of the main research approaches and selected publications. The time after World War II passed in Poland in two directions: coping with the finished war trauma and simultaneously the experience of communist persecution trauma. First scientific publications appeared in the fifties and were focused on the research of former concentration camps prisoners (KZ-Syndrome)...
October 31, 2016: Psychiatria Polska
Silvio Mario Meloni, Sascha Aleksandear Jovanovic, Milena Pisano, Marco Tallarico
PURPOSE: To test the hypothesis that platform switching and regular platform implants would have different outcomes in single-tooth replacement against the alternative hypothesis of no difference. MATERIAL AND METHODS: This study was designed as a randomised controlled split-mouth trial. Eighteen patients with bilaterally missing single premolars or molars to be restored with implant-supported single crowns, were consecutively enrolled. Implant sites were randomly assigned to be treated according to the platform switching concept (PS group), or with matching implant-abutment diameters (RP group)...
2016: European Journal of Oral Implantology
P Boya
Autophagy is a catabolic pathway that promotes the degradation and recycling of cellular components. Proteins, lipids, and even whole organelles are engulfed in autophagosomes and delivered to the lysosome for elimination. In response to stress, autophagy mediates the degradation of cell components, which are recycled to generate the nutrients and building blocks required to sustain cellular homeostasis. Moreover, it has an important role in cellular quality control, particularly in neurons, in which the total burden of altered proteins and damaged organelles cannot be reduced by redistribution to daughter cells through cell division...
December 16, 2016: Eye
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