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V Brychtová, R Šefr, R Hrstka, P Vídeňská, B Bencsiková, B Hanáková, L Zdražilová Dubská, R Nenutil, E Budinská
BACKGROUND: Colorectal carcinoma (CRC) is third most common cancer worldwide with very heterogenous character. In most cases, it is caused by sporadic events leading to disruption of epithelial cells of the colon. The minority evolves from germline mutations associated with hereditary cancer syndromes. Mechanisms leading to mutations of oncogenes, tumour suppressors and genes of DNA repair mechanisms include: 1. chromosomal instability, 2. microsatellite instability and 3. CpG island methylator phenotype...
2017: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
Megan Wasson, Paul Magtibay, Paul Magtibay, Javier Magrina
STUDY OBJECTIVE: To determine the incidence and impact of occult uterine malignancy following vaginal hysterectomy and uncontained morcellation. DESIGN: An Institutional Review Board-approved retrospective cohort study (Canadian Task Force classification II-2). SETTING: Three academic medical centers. PATIENTS: All women who underwent vaginal hysterectomy between January 1, 2008, and August 31, 2015, at 3 institutions were considered for inclusion in the study...
May 2017: Journal of Minimally Invasive Gynecology
Aysel Veyisoglu, Lorena Carro, Kiymet Guven, Demet Cetin, Cathrin Spröer, Peter Schumann, Hans-Peter Klenk, Michael Goodfellow, Nevzat Sahin
A Micromonospora strain, designated DS3186(T), isolated from sediment collected from the Black Sea off the Yason Peninsula, Ordu, Turkey, was examinated using a polyphasic approach. The strain was found to have chemotaxonomic, morphological and phylogenetic properties consistent with its clasification in the genus Micromonospora. A comparative 16S rRNA gene sequence analysis showed that the strain was closely related to the type strains of Micromonospora olivasterospora (99.0 %), Micromonospora equina (98...
July 2016: Antonie Van Leeuwenhoek
Raquel Vaquero-Cristóbal, Fernando Alacid, Francisco Esparza-Ros, José M Muyor, Pedro Ángel López-Miñarro
INTRODUCTION: previous studies have analysed the effect of mat Pilates practice on anthropometric variables and body composition in sedentaries. To date no researchs have investigated the benefits of Pilates on these variables after a short detraining period. OBJETIVE: to determine the effect of a 16-week mat Pilates program on anthropometric variables, body composition and somatotype of women with previous practice experience after three weeks of detraining period...
April 1, 2015: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
James Selby, Ash Prabhudesai
AIMS: To explore if post-operative day 3 C-reactive protein (CRP), the ratio of pre-operative to day 3 white cell count (WCC) and platelet count can be used to predict the risk of post-operative complication and stratify the severity of complications as defined by the Clavien-Dindo classification. METHODS: Data was obtained retrospectively on 127 patients who had elective bowel resection for malignancy between 2011 and 2013. Baseline demographics and clinical details were obtained including pre-operative and day 3 WCC and platelets and day 3 CRP...
October 2014: International Journal of Colorectal Disease
O A Castillo, G López-Fontana, I Vidal-Mora, E Alemán, G Aranguren
OBJECTIVE: To evaluate our long-term experience with laparoscopic partial nephrectomy (LPN) and to review the literature. MATERIAL AND METHODS: We performed a retrospective chart review, evaluating 227 consecutives laparoscopic partial nephrectomies performed between June 1995 and June 2010. Perioperative were recorded along with clinical a oncological outcomes. RESULTS: Mean age was 56.4 years (18-87) and clinical stages were T1a, T1b and T2 in 90...
March 2014: Actas Urologicas Españolas
Songthip Ounpraseuth, Shelly Y Lensing, Horace J Spencer, Ralph L Kodell
BACKGROUND: To estimate a classifier's error in predicting future observations, bootstrap methods have been proposed as reduced-variation alternatives to traditional cross-validation (CV) methods based on sampling without replacement. Monte Carlo (MC) simulation studies aimed at estimating the true misclassification error conditional on the training set are commonly used to compare CV methods. We conducted an MC simulation study to compare a new method of bootstrap CV (BCV) to k-fold CV for estimating clasification error...
2012: BMC Research Notes
Djuro Miskic, Josip Samardzic, Darko Kraljik, Ivana Mahovne, Blazenka Miskic, Leila Latic-Hodzic
We present an adolescent boy with unilateral supernumerary breast. It was a V type by Leung Clasification. Despite the average occurence between 0.22% and 6% in a normal population we have not had other cases in the last 20 years. The patient was an asthenic boy of sixteen in the IV stage of puberty. Sometimes he felt swelling and tenderness in this breast tissue two years ago. These symptoms became worse two months ago. At the admission he was symptom free. In the right hypochondrium inferomedially he had a nipple and areola with a small part of the glandular tissue...
2012: Medical Archives
Prasanth Ampalam, Raga Deepthi, Padma Vadaparty
BACKGROUND: Schizophrenia is one of the severe forms of mental illness which demands enormous personal and economical costs. Recent years have attracted considerable interest in the dual problem of depression in schizophrenia and its relation to insight. Most clinicians believe that poor insight in patients with schizophrenia, though problematic for treatment adherence, may be protective with respect to suicide. The assumption is that patients who do not believe that they are ill are less likely to be suicidal...
January 2012: Indian Journal of Psychological Medicine
Silvia Ghimpu, Laura Bozomitu, E Cîrdei, Doina Mihlăilă, D Boldureanu, D Moraru
UNLABELLED: The purpose of of this study is to identify IELs through immunocytochemistry stains for counting infiltration duodenal mucosa with T lymphocytes in children with celiac disease. MATERIAL AND METHOD: It was selected up simptomatology (abdominal pain, anorexia, failure thrive, chronic diarheea), features immunology(positifs tissue transglutaminase antibodies) and considering the histopathologic results (IELs > 30/100 enterocytes, crypt hyperplasia and villous atrophy) we made two groups: first group (13 children with celiac disease of 53 children with celiac disease) and second group (13 children with chronic duodenitis nonspecific)...
January 2010: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
Antonio Piñero-Madrona, Luis Polo-García, José Luis Alonso-Romero, Juan Salinas-Ramos, Manuel Canteras-Jordana, Joaquín Sola-Pérez, Pedro J Galindo-Fernández, Julián Illana-Moreno, Juan Bermejo-López, Agustín Navarrete-Montoya, Pascual Parrilla-Paricio
BACKGROUND: The aim of this paper is to determine the possible association between five different profiles of immunohistochemical expression related to clinical, histopathological and immunohistochemical known prognostic value variables for breast cancer. MATERIAL AND METHOD: A total of 194 breast carcinoma tumour samples were studied. In this study five groups or immunohistochemical profiles were defined, based on expression of hormone receptors (oestrogen or progesterone) and/or Her2/neu (luminal-type A, luminal-type B, mixed profile, Her2/neu profile and triple-negative-type profile) and we studied whether there are differences between them with regard to clinical, histopathological and immunohistochemical variables that have a known prognostic significance...
September 2008: Cirugía Española
P Navarro Medina, A Blanco Diez, J L Artiles Hernández, N Chesa Ponce
OBJECTIVES: Analyze the role of the Computerized Axial Tomography (TAC) like image study of pre-surgery stadification, in the subjected patients to radical cystectomy, for the treatment of muscle infiltrate bladder cancer. METHODS: Retrospective study of cohorts on 63 subjected patients to radical cystectomy for bladder cancer, in oneself service, between january of 1995 and december of 2.005. The capacity of the TAC was determined for the stadification bladder (pT), node (pN) and the results were compared, with the obtained ones in the pathological anatomy after the radical cystectomy, acording to TNM clasification...
May 2008: Actas Urologicas Españolas
Michał Tomiak, Jarosław Czubak
Tibia ankle fractures and traumatic injuries of the ankle-tibia joint area are one of the most intractable problems in orthopedic and traumatic surgery. Because of the displacement of these fractures they require precise opening of the joint surface area to undertake the early repositioning in order to gain eficient walk. The objective of this paper was to evaluate and compare the final results of nonoperative and operative treament methods, specificlly the two most common prognosis values of tibia ankle fracture clasifications by Danis-Weber and Lauge-Hansen...
November 2007: Chirurgia Narzadów Ruchu i Ortopedia Polska
S Cakić, Lj Janković
We present the results of clinical and laboratory studies of HIV seropositive individuals. Twenty individuals in different stages of HIV infection (CDC clasification) and 20 healthy individuals were included in this study. The number of leucocytes, differential leucocyte count, number of CD4+ T lymphocytes and CD4/CD8 index were determined. Periodontal staus was determined by using plaque index (PI), gingival index (GI) and periodontal pocket depth (PPD). Fourty percent of HIV seroposiotive patients showed oral eflorescences and 35% confirmed the presence of subjective disturbances in oral cavity...
July 1995: Srpski Arhiv za Celokupno Lekarstvo
Marcin Domzalski, Marek Synder, Marek Drobniewski
Background. Developmental dysplasia of the hip is still an important issue in orthopedic practice. Even though the number of patients who require surgical correction has decreased in the last 20 years, we still have patients with early dysplastic coxarthriosis. The aim of our study was to assess at maturity the reconstruction of the hip joint among patients surgically treated in childhood using Dega and Salter pelvic osteotomies. Material and methods. Our material consisted of 102 patients who were surgically treated in our clinic for DDH using Dega and Salter osteotomy, with a minimum of 15 years of follow-up...
February 28, 2004: Ortopedia, Traumatologia, Rehabilitacja
Janusz Popko, Wojciech Zalewski, Elzbieta Król, Paweł Szeparowicz
Background. Treatment of congenital hip dysplasia, when implemented in the first weeks of life, gives a good outcome. Very few publications, however, have addressed the anatomical remodeling of the affected hip. In this study, we evaluate the anatomical outcome of the treatment applied. Material and methods. We examined 89 children diagnosed with congenital hip dysplasia in the first three months of life and then treated with an abduction device, for a total of 148 hips. The time of follow-up varied from 8 to 13 years...
February 28, 2006: Ortopedia, Traumatologia, Rehabilitacja
Sonia M Moscoso-Veloza, Gloria F Ramírez-Cubillos, José J López-Gutierrez, Bárbara E Gerena-Useche
OBJECTIVE: This study was carried out in order to identify, document and assess suspect of Adverse Drug Reactions (ADR) that are report to pharmacovigilance program of Suba Hospital. METHODOLOGY: It was carried out an observational, descriptive and longitudinal study, in all the patients that consulted to the services of Urgencies and External Consultation, in the Hospital of Suba of the Bogotá city. RESULTS: During the period of study 46 reports of suspicion of ADR were received, from those which 26 (56,6 %) corresponded to consultation reason, the 20 remaining it was indoor patient ...
May 2006: Revista de Salud Pública
J Flieger, R Swieboda, M Tatarczak
Salting-out thin-layer chromatography of several chosen sulphonamides on silica gel has been examined with aqueous solutions of salts: sulphates, chlorides, nitrates, phosphates, acetates, thiocyanates. It was established that applied salts have different effects on retention of sulphonamides accordingly to Hofmeister's clasification (e.g. kosmotropes, chaotropes and neutral). The parameters of the linear regression analysis of dependences between the R(M) values and concentration of the salt in the eluent system were correlated with QSAR ones...
February 1, 2007: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
S Jesić, R Radulović, D Djerić, V Nesić, M Dimitrijević, Z Petrović, N Arsović, Z Arsić-Mandarić
Carcinoma of the external meatus is a rare disease and a challenge to treat. Demographic and clinical characteristics of this disease are discussed for 14 patients treated in the Institute of Otorhinolaryngonlogy and Maxillofacial Surgery during the period 1993-2003. using four different clasification of the disease. All patients were treated surgically with postoperative radiotherapy. Five years survival is 100% for the II and II stage of the disease for all clasifications, and 75% for the III stage according to Pitsburg clasiffication...
2004: Acta Chirurgica Iugoslavica
R Grönqvist, M Hirvonen, A Tuusa
Tribollogically and biomechanically valid slip-resistance measurement methods are needed urgently to facilitate new developments for improving the safety of footwear and floor coverings. Objective coefficient-of-friction measurements and subjective walking experiments were compared to scrutinize and validate anti-slip assessments of the shoe-floor interface. Four shoe types were tested on a smooth stainless steel floor contaminated with viscous glycerol. The friction utilization ratio during one step, the sliding distance, and the subjective rating of slipperiness were evaluated by seven test subjects in 420 walking trials...
August 1993: Applied Ergonomics
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