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https://www.readbyqxmd.com/read/28100231/can-screening-instruments-accurately-determine-poor-outcome-risk-in-adults-with-recent-onset-low-back-pain-a-systematic-review-and-meta-analysis
#1
Emma L Karran, James H McAuley, Adrian C Traeger, Susan L Hillier, Luzia Grabherr, Leslie N Russek, G Lorimer Moseley
BACKGROUND: Delivering efficient and effective healthcare is crucial for a condition as burdensome as low back pain (LBP). Stratified care strategies may be worthwhile, but rely on early and accurate patient screening using a valid and reliable instrument. The purpose of this study was to evaluate the performance of LBP screening instruments for determining risk of poor outcome in adults with LBP of less than 3 months duration. METHODS: Medline, Embase, CINAHL, PsycINFO, PEDro, Web of Science, SciVerse SCOPUS, and Cochrane Central Register of Controlled Trials were searched from June 2014 to March 2016...
January 19, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28081371/gwas-identifies-new-loci-for-painful-temporomandibular-disorder
#2
A E Sanders, D Jain, T Sofer, K F Kerr, C C Laurie, J R Shaffer, M L Marazita, L M Kaste, G D Slade, R B Fillingim, R Ohrbach, W Maixner, T Kocher, O Bernhardt, A Teumer, C Schwahn, K Sipilä, R Lähdesmäki, M Männikkö, P Pesonen, M Järvelin, C M Rizzatti-Barbosa, C B Meloto, M Ribeiro-Dasilva, L Diatchenko, P Serrano, S B Smith
Temporomandibular disorder (TMD) is a musculoskeletal condition characterized by pain and reduced function in the temporomandibular joint and/or associated masticatory musculature. Prevalence in the United States is 5% and twice as high among women as men. We conducted a discovery genome-wide association study (GWAS) of TMD in 10,153 participants (769 cases, 9,384 controls) of the US Hispanic Community Health Study/Study of Latinos (HCHS/SOL). The most promising single-nucleotide polymorphisms (SNPs) were tested in meta-analysis of 4 independent cohorts...
January 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28073851/increased-risk-of-adverse-neurocognitive-outcomes-with-proprotein-convertase-subtilisin-kexin-type-9-inhibitors
#3
Abdur Rahman Khan, Chirag Bavishi, Haris Riaz, Talha A Farid, Sobia Khan, Michel Atlas, Glenn Hirsch, Sohail Ikram, Roberto Bolli
BACKGROUND: There is encouraging evidence of the efficacy of proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors; however, their long-term safety remains unclear. We performed a meta-analysis of studies to evaluate the long-term safety of PCSK9 inhibitors. METHODS AND RESULTS: Our search strategy yielded 11 studies (9 smaller early-phase and 2 larger outcome trials). The outcomes assessed were cumulative serious adverse events, musculoskeletal adverse events, neurocognitive adverse events, and stroke...
January 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28068167/vehicle-exposure-and-spinal-musculature-fatigue-in-military-warfighters-a-meta-analysis
#4
Roger O Kollock, Kenneth E Games, Alan E Wilson, JoEllen M Sefton
CONTEXT:  Spinal musculature fatigue from vehicle exposure may place warfighters at risk for spinal injuries and pain. Research on the relationship between vehicle exposure and spinal musculature fatigue is conflicting. A better understanding of the effect of military duty on musculoskeletal function is needed before sports medicine teams can develop injury-prevention programs. OBJECTIVE:  To determine if the literature supports a definite effect of vehicle exposure on spinal musculature fatigue...
November 2016: Journal of Athletic Training
https://www.readbyqxmd.com/read/28068166/risk-factors-for-injuries-during-military-static-line-airborne-operations-a-systematic-review-and-meta-analysis
#5
Joseph Knapik, Ryan Steelman
OBJECTIVE:  To identify and analyze articles in which the authors examined risk factors for soldiers during military static-line airborne operations. DATA SOURCES:  We searched for articles in PubMed, the Defense Technical Information Center, reference lists, and other sources using the key words airborne, parachuting, parachutes, paratrooper, injuries, wounds, trauma, and musculoskeletal. STUDY SELECTION:  The search identified 17 684 potential studies...
November 2016: Journal of Athletic Training
https://www.readbyqxmd.com/read/28059578/a-bayesian-meta-analytic-approach-for-safety-signal-detection-in-randomized-clinical-trials
#6
Motoi Odani, Satoru Fukimbara, Tosiya Sato
BACKGROUND/AIM: Meta-analyses are frequently performed on adverse event data and are primarily used for improving statistical power to detect safety signals. However, in the evaluation of drug safety for New Drug Applications, simple pooling of adverse event data from multiple clinical trials is still commonly used. We sought to propose a new Bayesian hierarchical meta-analytic approach based on consideration of a hierarchical structure of reported individual adverse event data from multiple randomized clinical trials...
January 1, 2017: Clinical Trials: Journal of the Society for Clinical Trials
https://www.readbyqxmd.com/read/28054255/evaluation-of-resistance-training-to-improve-muscular-strength-and-body-composition-in-cancer-patients-undergoing-neoadjuvant-and-adjuvant-therapy-a-meta-analysis
#7
REVIEW
Camila S Padilha, Poliana Camila Marinello, Daniel A Galvão, Robert U Newton, Fernando H Borges, Fernando Frajacomo, Rafael Deminice
PURPOSE: Muscle atrophy and strength decline are two of the most prominent characteristics in cancer patients undergoing cancer therapy, leading to decreased functional ability and reduced quality of life. Therefore, the aim is to systematically review research evidence of the effects of resistance exercise (RE) on lower-limb muscular strength, lean body mass (LBM), and body fat (BF) in cancer patients undertaking neoadjuvant or adjuvant therapy. METHODS: This research was conducted using the following online database: Clinical Trial Register, Cochrane Trial Register, PubMed, SPORT Discus, and SciELO, from September 2014 until May 2015...
January 4, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/27989329/nonpharmacologic-treatment-of-pain
#8
REVIEW
Anna Monica Agoston, Christine B Sieberg
Pain is a complex biopsychosocial experience that is influenced by neurological processes and psychosocial factors. Systematic reviews and meta-analyses of randomized controlled trials of psychological interventions have demonstrated evidence for psychological approaches in treating procedural pain and multiple types of chronic pain, including headaches, abdominal pain, and musculoskeletal pain. This article is directed toward clinicians and would provide an overview of cognitive-behavioral therapy, including specific cognitive-behavioral techniques for pediatric pain...
August 2016: Seminars in Pediatric Neurology
https://www.readbyqxmd.com/read/27919918/effectiveness-of-foot-orthoses-and-shock-absorbing-insoles-for-the-prevention-of-injury-a-systematic-review-and-meta-analysis
#9
Daniel R Bonanno, Karl B Landorf, Shannon E Munteanu, George S Murley, Hylton B Menz
OBJECTIVE: To investigate the evidence relating to the effectiveness of foot orthoses and shock-absorbing insoles for the prevention of musculoskeletal injury. DESIGN: Systematic review and meta-analysis. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Clinical trials evaluating the effectiveness of foot orthoses and shock-absorbing insoles for the prevention of injury. DATA SOURCES: Cochrane Library, CINAHL, EMBASE, MEDLINE and SPORTDiscus from their inception up to the first week of June 2016...
December 5, 2016: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/27896647/changes-in-non-diabetic-comorbid-disease-status-following-laparoscopic-vertical-sleeve-gastrectomy-lvsg-versus-laparoscopic-roux-en-y-gastric-bypass-lrygb-procedures-a-systematic-review-of-randomized-controlled-trials
#10
Emma Osland, Rossita Mohamad Yunus, Shahjahan Khan, Breda Memon, Muhammed Ashraf Memon
PURPOSE: Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic vertical sleeve gastrectomy (LVSG) have been proposed as cost-effective strategies to manage obesity-related chronic disease. The aim of this systematic review was to study the peer review literature regarding postoperative nondiabetic comorbid disease resolution or improvement reported from randomized controlled trials (RCTs) comparing LVSG and LRYGB procedures. MATERIAL AND METHODS: RCTs comparing postoperative comorbid disease resolution such as hypertension, dyslipidemia, obstructive sleep apnea, joint and musculoskeletal conditions, gastroesophageal reflux disease, and menstrual irregularities following LVSG and LRYGB were included for analysis...
November 28, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27884862/associations-of-occupational-standing-with-musculoskeletal-symptoms-a-systematic-review-with-meta-analysis
#11
REVIEW
Pieter Coenen, Lisa Willenberg, Sharon Parry, Joyce W Shi, Lorena Romero, Diana M Blackwood, Christopher G Maher, Genevieve N Healy, David W Dunstan, Leon M Straker
OBJECTIVE: Given the high exposure to occupational standing in specific occupations, and recent initiatives to encourage intermittent standing among white-collar workers, a better understanding of the potential health consequences of occupational standing is required. We aimed to review and quantify the epidemiological evidence on associations of occupational standing with musculoskeletal symptoms. DESIGN: A systematic review was performed. Data from included articles were extracted and described, and meta-analyses conducted when data were sufficiently homogeneous...
November 24, 2016: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/27852100/withdrawn-acupuncture-for-neck-disorders
#12
REVIEW
Kien Trinh, Nadine Graham, Dominik Irnich, Ian D Cameron, Mario Forget
BACKGROUND: Neck pain is one of the three most frequently reported complaints of the musculoskeletal system. Treatments for neck pain are varied, as are perceptions of benefit. Acupuncture has been used as an alternative to more conventional treatment for musculoskeletal pain. This review summarises the most current scientific evidence on the effectiveness of acupuncture for acute, subacute and chronic neck pain. This update replaces our 2006 Cochrane review update on this topic. OBJECTIVES: To determine the effects of acupuncture for adults with neck pain, with focus on pain relief, disability or functional measures, patient satisfaction and global perceived effect...
17, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27812455/kinetics-and-kinematics-of-diabetic-foot-in-type-2-diabetes-mellitus-with-and-without-peripheral-neuropathy-a-systematic-review-and-meta-analysis
#13
REVIEW
Animesh Hazari, Arun G Maiya, K N Shivashankara, Ioannis Agouris, Ashma Monteiro, Radhika Jadhav, Sampath Kumar, C G Shashi Kumar, Shreemathi S Mayya
BACKGROUND: Diabetes mellitus patients are at increased risk of developing diabetic foot with peripheral neuropathy, vascular and musculoskeletal complications. Therefore they are prone to develop frequent and often foot problems with a relative high risk of infection, gangrene and amputation. In addition, altered plantar pressure distribution is an important etiopathogenic risk factor for the development of foot ulcers. Thus the review on study of foot kinematic and kinetic in type 2 diabetes mellitus to understand the biomechanical changes is important...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27801744/long-term-effects-of-habitual-barefoot-running-and-walking-a-systematic-review
#14
Karsten Hollander, Christoph Heidt, Babette van der Zwaard, Klaus-Michael Braumann, Astrid Zech
INTRODUCTION: Barefoot locomotion is widely believed to be beneficial for motor development and biomechanics but are implied to be responsible for foot pathologies and running-related injuries. While most of available studies focused on acute effects of barefoot running and walking little is known regarding the effects of long-term barefoot vs. shod locomotion. The purpose of this study was to systematically review the literature to evaluate current evidence of habitual barefoot (HB) vs...
October 31, 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27796924/a-comparison-of-peripheral-imaging-technologies-for-bone-and-muscle-quantification-a-mixed-methods-clinical-review
#15
REVIEW
Andy Kin On Wong
PURPOSE OF REVIEW: Bone and muscle peripheral imaging technologies are reviewed for their association with fractures and frailty. A narrative systematized review was conducted for bone and muscle parameters from each imaging technique. In addition, meta-analyses were performed across all bone quality parameters. RECENT FINDINGS: The current body of evidence for bone quality's association with fractures is strong for (high-resolution) peripheral quantitative computed tomography (pQCT), with trabecular separation (Tb...
October 28, 2016: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/27770542/sertraline-use-in-the-first-trimester-and-risk-of-congenital-anomalies-a-systemic-review-and-meta-analysis-of-cohort-studies
#16
Zi-Qi Shen, Shan-Yan Gao, Shawn Xiang Li, Tie-Ning Zhang, Cai-Xia Liu, Hai-Chen Lv, Yuan Zhang, Ting-Ting Gong, Xin Xu, Chao Ji, Qi-Jun Wu, Da Li
AIM: To perform a meta-analysis of available cohort studies on the association between sertraline use by pregnant women in the first trimester and the findings of congenital anomalies in infants. METHODS: A comprehensive search of articles published from the index date up to 31(st) December 2015 investigating the aforementioned associations was conducted on PubMed and Web of Science. Mesh headings used included the terms "serotonin reuptake inhibitor," "sertraline," "congenital anomalies" and "obstetrical outcome...
October 22, 2016: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/27764035/the-persistence-of-the-effects-of-acupuncture-after-a-course-of-treatment-a-meta-analysis-of-patients-with-chronic-pain
#17
H MacPherson, E A Vertosick, N E Foster, G Lewith, K Linde, K J Sherman, C M Witt, A J Vickers
There is uncertainty regarding how long the effects of acupuncture treatment persist after a course of treatment. We aimed to determine the trajectory of pain scores over time following acupuncture, using a large individual patient dataset from high quality randomized trials of acupuncture for chronic pain. The available individual patient dataset included 29 trials and 17,922 patients. The chronic pain conditions included musculoskeletal pain (low back, neck and shoulder), osteoarthritis of the knee and headache/migraine...
October 17, 2016: Pain
https://www.readbyqxmd.com/read/27761590/the-role-of-calcium-supplementation-in-healthy-musculoskeletal-ageing-an-expert-consensus-meeting-of-the-european-society-for-clinical-and-economic-aspects-of-osteoporosis-osteoarthritis-and-musculoskeletal-diseases-esceo-and-the-international-foundation-for
#18
REVIEW
N C Harvey, E Biver, J-M Kaufman, J Bauer, J Branco, M L Brandi, O Bruyère, V Coxam, A Cruz-Jentoft, E Czerwinski, H Dimai, P Fardellone, F Landi, J-Y Reginster, B Dawson-Hughes, J A Kanis, R Rizzoli, C Cooper
The place of calcium supplementation, with or without concomitant vitamin D supplementation, has been much debated in terms of both efficacy and safety. There have been numerous trials and meta-analyses of supplementation for fracture reduction, and associations with risk of myocardial infarction have been suggested in recent years. In this report, the product of an expert consensus meeting of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Foundation for Osteoporosis (IOF), we review the evidence for the value of calcium supplementation, with or without vitamin D supplementation, for healthy musculoskeletal ageing...
October 20, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27755324/prognostic-factors-for-return-to-work-following-surgery-for-carpal-tunnel-syndrome-a-systematic-review
#19
Susan Peters, Venerina Johnston, Sonia Hines, Mark Ross, Michel Coppieters
BACKGROUND: Carpal tunnel syndrome (CTS) is a common problem, that can be effectively managed by surgery. Screening for prognostic factors is important to identify workers who are at a greater risk of a poor work outcome in order to implement tailored interventions to facilitate their return-to-work. OBJECTIVE: To synthesize the best available evidence on the association of preoperative prognostic factors with work-related outcomes in people who have undergone carpal tunnel surgery...
September 2016: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/27707631/stabilization-exercise-compared-to-general-exercises-or-manual-therapy-for-the-management-of-low-back-pain-a-systematic-review-and-meta-analysis
#20
REVIEW
Mansueto Gomes-Neto, Jordana Moura Lopes, Cristiano Sena Conceição, Anderson Araujo, Alécio Brasileiro, Camila Sousa, Vitor Oliveira Carvalho, Fabio Luciano Arcanjo
AIM: We performed a systematic review with a meta-analysis to examine the efficacy of stabilization exercises versus general exercises or manual therapy in patients with low back pain. DESIGN: We searched MEDLINE, Cochrane Controlled Trials, Scielo, and CINAHL (from the earliest date available to November 2014) for randomized controlled trials that examined the efficacy of stabilization exercises compared to general exercises or manual therapy on pain, disability, and function in patients with low back pain...
January 2017: Physical Therapy in Sport
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