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https://www.readbyqxmd.com/read/28636752/comparison-of-effect-sizes-between-enriched-and-non-enriched-trials-of-analgesics-for-chronic-musculoskeletal-pain-a-systematic-review
#1
Tie P Yamato, Chris G Maher, Bruno T Saragiotto, Christina Abdel Shaheed, Anne M Moseley, Chung-Wei Christine Lin, Bart Koes, Andrew J McLachlan
OBJECTIVE: To investigate the use of an enriched study design on the estimates of treatment effect in analgesic trials for chronic musculoskeletal pain METHODS: Database searches were conducted from 2004 to 2014. We included randomised placebo-controlled trials evaluating pain medications for chronic musculoskeletal pain. Methodological quality was assessed using the PEDro scale. The estimates of treatment effect on pain and adverse events were compared between enriched and non-enriched designs...
June 21, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28622749/general-exercise-does-not-improve-long-term-pain-and-disability-in-individuals-with-whiplash-associated-disorders-a-systematic-review
#2
Alexandra Griffin, Andrew Leaver, Niamh Moloney
Study Design Systematic review of randomized controlled trials. Background General exercise, defined as purposeful physical activity involving repetitive exercises, and incorporating multiple muscle groups, is frequently used in the management of whiplash associated disorders (WAD). Evidence supporting its efficacy is not well established. Objectives To determine whether general exercise is effective in reducing pain and disability in people with WAD. Methods Studies published in English in peer-reviewed journals between January 1990 and May 2015 were eligible if they evaluated a general exercise intervention compared with a different intervention or control...
June 16, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28614193/meta-analysis-of-cigarette-smoking-and-musculoskeletal-injuries-in-military-training
#3
Sheryl A Bedno, Rhonda Jackson, Xiaoshu Feng, Imani L Walton, Michael R Boivin, David N Cowan
PURPOSE: Tobacco use is common among military personnel, as is musculoskeletal injury during training. In a review of the literature on musculoskeletal injuries there was mixed evidence on the role of smoking as a risk factor. The purpose of this study is to review and analyze the literature on the impact of cigarette smoking on lower extremity overuse injuries in military training. METHODS: We performed a literature search on articles published through October 2016...
June 13, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28600365/effect-of-physical-activity-and-dietary-restriction-interventions-on-weight-loss-and-the-musculoskeletal-function-of-overweight-and-obese-older-adults-with-knee-osteoarthritis-a-systematic-review-and-mixed-method-data-synthesis
#4
Asma S Alrushud, Alison B Rushton, Archontissa M Kanavaki, Carolyn A Greig
BACKGROUND: Despite the clinical recommendation of exercise and diet for people with knee osteoarthritis (OA), there are no systematic reviews synthesising the effectiveness of combining physical activity and dietary restriction interventions on the musculoskeletal function of overweight and obese older adults with knee OA. OBJECTIVE: To evaluate the effectiveness of combined physical activity and dietary restriction programmes on body weight, body mass index (BMI) and the musculoskeletal function of overweight and obese older adults with knee OA...
June 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/28596288/should-exercises-be-painful-in-the-management-of-chronic-musculoskeletal-pain-a-systematic-review-and-meta-analysis
#5
REVIEW
Benjamin E Smith, Paul Hendrick, Toby O Smith, Marcus Bateman, Fiona Moffatt, Michael S Rathleff, James Selfe, Pip Logan
BACKGROUND: Chronic musculoskeletal disorders are a prevalent and costly global health issue. A new form of exercise therapy focused on loading and resistance programmes that temporarily aggravates a patient's pain has been proposed. The object of this review was to compare the effect of exercises where pain is allowed/encouraged compared with non-painful exercises on pain, function or disability in patients with chronic musculoskeletal pain within randomised controlled trials. METHODS: Two authors independently selected studies and appraised risk of bias...
June 8, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28513455/glucose-tolerance-disorders-during-treatment-with-glucocorticoids-in-patients-with-inflammatory-diseases-of-the-musculoskeletal-system-based-on-the-analysis-of-data-from-the-literature-and-own-research-results
#6
Piotr Dąbrowski, Maria Majdan
Glucocorticoids are among the most frequently used anti-inflammatory and immunosuppressive drugs. They are widely used in the treatment of numerous autoimmune disorders. However, the treatment with glucocorticoids is connected with the risk of a number of side effects. Among them, glucose tolerance disorders play an important role. The results of meta-analyses show that the risk of diabetes is from 1.4 to 2.5 times higher in the case of treated patients in comparison to the general population. Glucocorticoids can directly impair pancreatic β-cell secretion...
May 4, 2017: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/28513059/fluoxetine-and-congenital-malformations-a-systematic-review-and-meta-analysis-of-cohort-studies
#7
Shan-Yan Gao, Qi-Jun Wu, Tie-Ning Zhang, Zi-Qi Shen, Cai-Xia Liu, Xin Xu, Chao Ji, Yu-Hong Zhao
AIMS: To investigate the safety of fluoxetine use during pregnancy, and to better understand the relationship between maternal fluoxetine use during the first trimester and congenital malformations in infants. METHODS: PubMed and Web of Science databases were systematically searched from inception to 21 March 2016. Additional studies were identified in a manual search of the reference lists. Two reviewers independently extracted data. A third reviewer checked the data...
May 17, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28489768/prevalence-of-comorbidities-in-chronic-obstructive-pulmonary-disease-patients-a-meta-analysis
#8
REVIEW
Hong-Lei Yin, Shi-Qi Yin, Qing-Yan Lin, Ying Xu, Hong-Wei Xu, Tao Liu
BACKGROUND: This study compares the prevalence rates of comorbidities between chronic obstructive pulmonary disease (COPD) and non-COPD control patients reported in literature. METHOD: Literature was searched in several electronic databases. After the selection of studies by following précised eligibility criteria, meta-analyses of odds ratios (ORs) were carried out with subgroup and sensitivity analyses under random effects model. RESULTS: Eleven studies (47,695,183 COPD and 47,924,876 non-COPD control patients' data) were used for meta-analysis...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28486337/hypertrophic-effects-of-concentric-versus-eccentric-muscle-actions-a-systematic-review-and-meta-analysis
#9
Brad J Schoenfeld, Dan Ogborn, Andrew D Vigotsky, Martino Franchi, James W Krieger
Controversy exists as to whether different dynamic muscle actions produce divergent hypertrophic responses. The purpose of this paper was to conduct a systematic review and meta-analysis of randomized controlled trials comparing the hypertrophic effects of concentric versus eccentric training in healthy adults following regimented resistance training (RT). Studies were deemed eligible for inclusion if they met the following criteria: 1) were an experimental trial published in an English-language refereed journal; 2) directly compared concentric and eccentric actions without the use of external implements (i...
May 5, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28484944/prolotherapy-for-osteoarthritis-and-tendinopathy-a-descriptive-review
#10
REVIEW
David Rabago, Bobby Nourani
PURPOSE OF REVIEW: Osteoarthritis and overuse tendinopathy are common chronic conditions of high societal and patient burden. The precise etiology of pain and disability in both conditions is multifactorial and not well understood. Patients are often refractory to conservative therapy. The development of new therapeutic options in both conditions is a public health priority. Prolotherapy is an injection-based outpatient regenerative therapy for chronic musculoskeletal conditions, including osteoarthritis and tendinopathy...
June 2017: Current Rheumatology Reports
https://www.readbyqxmd.com/read/28477328/can-chronic-disease-be-managed-through-integrated-care-cost-effectively-evidence-from-a-systematic-review
#11
J Cronin, A Murphy, E Savage
BACKGROUND: The increase in demand for integrated care models to manage chronic disease is a challenge for the Irish health system, which is traditionally organised around the acute hospital services. Implementing integrated care programmes requires significant investment, and thus, their economic impact requires consideration. AIMS: This paper updates the previous evidence on the cost-effectiveness of integrated care programmes to support the development of a cost-effective integrated care programme for chronic disease management...
May 5, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28476110/restriction-in-lateral-bending-range-of-motion-lumbar-lordosis-and-hamstring-flexibility-predicts-the-development-of-low-back-pain-a-systematic-review-of-prospective-cohort-studies
#12
Sean G Sadler, Martin J Spink, Alan Ho, Xanne Janse De Jonge, Vivienne H Chuter
BACKGROUND: Low back pain (LBP) is an increasingly common condition worldwide with significant costs associated with its management. Identification of musculoskeletal risk factors that can be treated clinically before the development of LBP could reduce costs and improve the quality of life of individuals. Therefore the aim was to systematically review prospective cohort studies investigating lower back and / or lower limb musculoskeletal risk factors in the development of LBP. METHODS: MEDLINE, EMBASE, AMED, CINAHL, SPORTDiscus, and the Cochrane Library were searched from inception to February 2016...
May 5, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28456671/lateral-lumbar-interbody-fusion-a-systematic-review-of-complication-rates
#13
Fady Y Hijji, Ankur S Narain, Daniel D Bohl, Junyoung Ahn, William W Long, Jacob V DiBattista, Krishna T Kudaravalli, Kern Singh
BACKGROUND CONTEXT: Lateral lumbar interbody fusion (LLIF) is a frequently utilized technique for the treatment of lumbar pathology. Despite its overall success, LLIF has been associated with a unique set of complications. However, there has been inconsistent evidence regarding the complication rate of this approach. PURPOSE: To perform a systematic review analyzing the rates of medical and surgical complications associated with LLIF. STUDY DESIGN: Systematic Review PATIENT SAMPLE: 6819 patients who underwent LLIF reported in clinical studies through June 2016...
April 26, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28452070/effect-of-exergames-on-musculoskeletal-pain-a-systematic-review-and-meta-analysis
#14
REVIEW
D Collado-Mateo, E Merellano-Navarro, P R Olivares, J García-Rubio, N Gusi
The main objective was to systematically review the scientific literature about the effects of exergame-based interventions on musculoskeletal pain, as well as to provide directions for the clinical practice. A systematic search was conducted in four electronic databases following PRISMA guidelines. The inclusion criteria were as follows: (a) the subjects were suffering musculoskeletal pain, (b) the study was randomized controlled trial (RCT), (c) intervention was based on exergames, (d) the article was written in English, and (e) the article was not an abstract or summary presented in a congress or conference...
April 27, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28399251/association-of-spinal-manipulative-therapy-with-clinical-benefit-and-harm-for-acute-low-back-pain-systematic-review-and-meta-analysis
#15
REVIEW
Neil M Paige, Isomi M Miake-Lye, Marika Suttorp Booth, Jessica M Beroes, Aram S Mardian, Paul Dougherty, Richard Branson, Baron Tang, Sally C Morton, Paul G Shekelle
Importance: Acute low back pain is common and spinal manipulative therapy (SMT) is a treatment option. Randomized clinical trials (RCTs) and meta-analyses have reported different conclusions about the effectiveness of SMT. Objective: To systematically review studies of the effectiveness and harms of SMT for acute (≤6 weeks) low back pain. Data Sources: Search of MEDLINE, Cochrane Database of Systematic Reviews, EMBASE, and Current Nursing and Allied Health Literature from January 1, 2011, through February 6, 2017, as well as identified systematic reviews and RCTs, for RCTs of adults with low back pain treated in ambulatory settings with SMT compared with sham or alternative treatments, and that measured pain or function outcomes for up to 6 weeks...
April 11, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28398983/effectiveness-of-educational-or-behavioral-interventions-on-adherence-to-phosphate-control-in-adults-receiving-hemodialysis-a-systematic-review
#16
Molly Milazi, Ann Bonner, Clint Douglas
BACKGROUND: People with end-stage kidney disease (ESKD) develop impaired excretion of phosphate. Hyperphosphatemia develops in ESKD as a result of the kidney's reduced ability to excrete ingested phosphate load and is characterized by high bone turnover and increased musculoskeletal morbidity including bone pain and muscle weakness. Increased serum phosphate levels are also associated with cardiovascular disease and associated mortality. These effects are significant considering that cardiovascular disease is the leading cause of death in ESKD, making phosphate control a crucial treatment goal...
April 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28382927/-occupational-exposure-to-psychosocial-factors-and-presence-of-musculoskeletal-disorders-in-nursing-staff-a-review-of-studies-and-meta-analysis
#17
REVIEW
Antonio Ramón Ballester Arias, Ana María García
BACKGROUND: There is scientific evidence that psychosocial factors are significantly associated with discomfort and / or pain musculoskeletal complaints in nursing staff. The objective of the research was to analyze the association between occupational exposure to psychosocial factors at work and musculoskeletal damage in nursing staff. METHODS: Systematic review and meta-analysis of studies published up to 2015 in English, French, Italian, Portuguese or Spanish evaluating the association between musculoskeletal disorders and psychosocial factors in the work of nursing staff...
April 7, 2017: Revista Española de Salud Pública
https://www.readbyqxmd.com/read/28382112/the-role-of-vitamin-d-in-maintaining-bone-health-in-older-people
#18
REVIEW
Thomas R Hill, Terry J Aspray
This review summarises aspects of vitamin D metabolism, the consequences of vitamin D deficiency, and the impact of vitamin D supplementation on musculoskeletal health in older age. With age, changes in vitamin D exposure, cutaneous vitamin D synthesis and behavioural factors (including physical activity, diet and sun exposure) are compounded by changes in calcium and vitamin D pathophysiology with altered calcium absorption, decreased 25-OH vitamin D [25(OH)D] hydroxylation, lower renal fractional calcium reabsorption and a rise in parathyroid hormone...
April 2017: Therapeutic Advances in Musculoskeletal Disease
https://www.readbyqxmd.com/read/28360142/do-functional-movement-screen-fms-composite-scores-predict-subsequent-injury-a-systematic-review-with-meta-analysis
#19
REVIEW
Robert W Moran, Anthony G Schneiders, Jesse Mason, S John Sullivan
AIM: This paper aims to systematically review studies investigating the strength of association between FMS composite scores and subsequent risk of injury, taking into account both methodological quality and clinical and methodological diversity. DESIGN: Systematic review with meta-analysis. DATA SOURCES: A systematic search of electronic databases was conducted for the period between their inception and 3 March 2016 using PubMed, Medline, Google Scholar, Scopus, Academic Search Complete, AMED (Allied and Complementary Medicine Database), CINAHL (Cumulative Index to Nursing and Allied Health Literature), Health Source and SPORTDiscus...
March 30, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28358173/return-to-work-coordination-programmes-for-improving-return-to-work-in-workers-on-sick-leave
#20
REVIEW
Nicole Vogel, Stefan Schandelmaier, Thomas Zumbrunn, Shanil Ebrahim, Wout El de Boer, Jason W Busse, Regina Kunz
BACKGROUND: To limit long-term sick leave and associated consequences, insurers, healthcare providers and employers provide programmes to facilitate disabled people's return to work. These programmes include a variety of coordinated and individualised interventions. Despite the increasing popularity of such programmes, their benefits remain uncertain. We conducted a systematic review to determine the long-term effectiveness of return-to-work coordination programmes compared to usual practice in workers at risk for long-term disability...
March 30, 2017: Cochrane Database of Systematic Reviews
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