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https://www.readbyqxmd.com/read/28955355/gene-regulatory-network-for-tapetum-development-in-arabidopsis-thaliana
#1
Dan-Dan Li, Jing-Shi Xue, Jun Zhu, Zhong-Nan Yang
In flowering plants, male gametophyte development occurs in the anther. Tapetum, the innermost of the four anther somatic layers, surrounds the developing reproductive cells to provide materials for pollen development. A genetic pathway of DYT1-TDF1-AMS-MS188 in regulating tapetum development has been proven. Here we used laser microdissection and pressure catapulting to capture and analyze the transcriptome data for the Arabidopsis tapetum at two stages. With a comprehensive analysis by the microarray data of dyt1, tdf1, ams, and ms188 mutants, we identified possible downstream genes for each transcription factor...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28949184/superpropulsion-of-droplets-and-soft-elastic-solids
#2
Christophe Raufaste, Gabriela Ramos Chagas, Thierry Darmanin, Cyrille Claudet, Frédéric Guittard, Franck Celestini
We investigate the behavior of droplets and soft elastic objects propelled with a catapult. Experiments show that the ejection velocity depends on both the projectile deformation and the catapult acceleration dynamics. With a subtle matching given by a peculiar value of the projectile/catapult frequency ratio, a 250% kinetic energy gain is obtained as compared to the propulsion of a rigid projectile with the same engine. This superpropulsion has strong potentialities: actuation of droplets, sorting of objects according to their elastic properties, and energy saving for propulsion engines...
September 8, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28889919/emerging-immunotherapy-in-advanced-renal-cell-carcinoma
#3
REVIEW
Prateek Mendiratta, Brian I Rini, Moshe C Ornstein
Immunotherapy has recently catapulted to the forefront of treatments for patients with solid tumors. Given its inherent immunogenic properties, renal cell carcinoma (RCC) has historically responded to immunotherapy and remains primed for further development. Although immunotherapy with high-dose interleukin 2 was a primary treatment for advanced RCC (aRCC), recent discoveries of key molecular and immunological alterations have led to the FDA-approval of nivolumab, an antiprogrammed cell death inhibitor, which has demonstrated an overall survival in patients with previously treated aRCC...
September 7, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28880690/cognitive-intervention-for-early-stage-dementia-research-and-techniques
#4
John W DenBoer
Dementia is a growing world-wide phenomenon, impacting more than six million people in the United States. Despite its high projected prevalence, it is a significantly under-estimated phenomena, with estimates ranging from 15 to 25% of the current U.S. POPULATION: The effect of the aging of the population and significant increase in life expectancy has combined to catapult dementia into the range of one of world's most alarming healthcare problems. Diverse and emerging literature in the area of cognitive prevention/intervention for mild cognitive impairment (MCI)/early stage dementia will be reviewed...
September 7, 2017: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/28872371/reliability-of-wearable-inertial-measurement-units-to-measure-physical-activity-in-team-handball
#5
Live S Luteberget, Benjamin R Holme, Matt Spencer
PURPOSE: The purpose of this study was to assess the reliability and sensitivity of commercially available inertial measurement units (IMU) to measure physical activity in team handball. METHOD: Twenty-two handball players were instrumented with two IMUs (OptimEye S5, Catapult Sports, Australia) taped together. They participated in either a laboratory assessment (n=10), consisting of seven team handball specific tasks, or field assessment (n=12) conducted in twelve training sessions...
September 5, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28858054/utilizing-microsensor-technology-to-quantify-match-demands-in-collegiate-women-s-volleyball
#6
Travis G Vlantes, Tucker Readdy
The purpose of this study was to quantify internal and external load demands of women's NCAA Division I collegiate volleyball competitions using microsensor technology and session rating of perceived exertion (S-RPE). Eleven collegiate volleyball players wore microsensor technology (Optimeye S5; Catapult Sports USA, Chicago, IL) during fifteen matches played throughout the 2016 season. Parameters examined include: Player load (PL), High impact load (HI PL), percentage of high impact load (% HI PL), Explosive efforts (EE) and jumps...
August 26, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28845068/accelerating-innovation-in-the-creation-of-biovalue-the-cell-and-gene-therapy-catapult
#7
John Gardner, Andrew Webster
The field of regenerative medicine (RM) has considerable therapeutic promise that is proving difficult to realize. As a result, governments have supported the establishment of intermediary agencies to "accelerate" innovation. This article examines in detail one such agency, the United Kingdom's Cell and Gene Therapy Catapult (CGTC). We describe CGTC's role as an accelerator agency and its value narrative, which combines both "health and wealth." Drawing on the notion of sociotechnical imaginaries, we unpack the tensions within this narrative and its instantiation as the CGTC cell therapy infrastructure is built and engages with other agencies, some of which have different priorities and roles to play within the RM field...
September 2017: Science, Technology & Human Values
https://www.readbyqxmd.com/read/28820856/perceived-wellness-associated-with-practice-and-competition-in-ncaa-division-i-football-players
#8
Aaron D Wellman, Sam C Coad, Patrick J Flynn, Ty K Siam, Christopher P McLellan
The present study assessed the influence of movement demands resulting from weekly practice sessions and games, on perceived wellness measurements taken post-game (Sunday) and 48 hours pre-game (Thursday) throughout the in-season period in National Collegiate Athletic Association (NCAA) division I football players. Thirty players were monitored using GPS receivers (Catapult Innovations OptimEye S5, Melbourne, Australia) during 12 games and 24 in-season practices. Movement variables included low-intensity distance, medium-intensity distance, high-intensity distance, sprint distance, total distance, player load, and acceleration and deceleration distance...
August 15, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28817506/maximum-distance-and-high-speed-distance-demands-by-position-in-ncaa-division-i-collegiate-football-games
#9
Gabriel J Sanders, Brad Roll, Corey A Peacock
Sanders, GJ, Roll, B, and Peacock, CA. Maximum distance and high-speed distance demands by position in NCAA division I collegiate football games. J Strength Cond Res 31(10): 2728-2733, 2017-The purpose of the study was to quantify the average and maximum distances traveled by National Collegiate Athletic Association division I football athletes during competitive games. Using global positioning system devices (Catapult Sports), total and low-, moderate-, and high-speed distances were quantified by each position...
October 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28817504/movement-demands-and-perceived-wellness-associated-with-preseason-training-camp-in-ncaa-division-i-college-football-players
#10
Aaron D Wellman, Sam C Coad, Patrick J Flynn, Mike Climstein, Christopher P McLellan
Wellman, AD, Coad, SC, Flynn, PJ, Climstein, M, and McLellan, CP. Movement demands and perceived wellness associated with preseason training camp in NCAA Division I college football players. J Strength Cond Res 31(10): 2704-2718, 2017-The aims of this study were to examine the movement demands of preseason practice in National Collegiate Athletic Association Division I college football players using portable global positioning system (GPS) technology and to assess perceived wellness associated with preseason practice to determine whether GPS-derived variables from the preceding day influence perceived wellness the following day...
October 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28777247/a-comparison-of-pre-season-and-in-season-practice-and-game-loads-in-ncaa-division-i-football-players
#11
Aaron D Wellman, Sam C Coad, Patrick J Flynn, Ty K Siam, Christopher P McLellan
The aim of the present study was to quantify the individual practice and game loads throughout an NCAA division I football season to determine if significant differences exist between the practice loads associated with pre-season training camp and those undertaken during the in-season period. Thirty-one NCAA division I football players were monitored using GPS and IA (MinimaxX S5; Catapult Innovations, Melbourne, Australia) during 22 pre-season practices, 36 in-season practices, and 12 competitions. The season was divided into four distinct phases for data analysis: pre-season week 1 (pre-season1), pre-season week 2 (pre-season2), pre-season week 3 (pre-season3), and 12 in-season weeks...
July 31, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28747394/asymmetric-drop-coalescence-launches-fungal-ballistospores-with-directionality
#12
Fangjie Liu, Roger L Chavez, S N Patek, Anne Pringle, James J Feng, Chuan-Hua Chen
Thousands of fungal species use surface energy to power the launch of their ballistospores. The surface energy is released when a spherical Buller's drop at the spore's hilar appendix merges with a flattened drop on the adaxial side of the spore. The launching mechanism is primarily understood in terms of energetic models, and crucial features such as launching directionality are unexplained. Integrating experiments and simulations, we advance a mechanistic model based on the capillary-inertial coalescence between the Buller's drop and the adaxial drop, a pair that is asymmetric in size, shape and relative position...
July 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28717518/the-sharing-of-radiological-images-by-professional-mixed-martial-arts-fighters-on-social-media
#13
George Rahmani, Cormac W Joyce, Peter McCarthy
BACKGROUND: Mixed martial arts is a sport that has recently enjoyed a significant increase in popularity. This rise in popularity has catapulted many of these "cage fighters" into stardom and many regularly use social media to reach out to their fans. An interesting result of this interaction on social media is that athletes are sharing images of their radiological examinations when they sustain an injury. PURPOSE: To review instances where mixed martial arts fighters shared images of their radiological examinations on social media and in what context they were shared...
June 2017: Acta Radiologica Open
https://www.readbyqxmd.com/read/28713465/a-comparison-of-gps-workload-demands-in-match-play-and-small-sided-games-by-the-positional-role-in-youth-soccer
#14
Mathew Beenham, David J Barron, John Fry, Howard H Hurst, Antonio Figueirdo, Steve Atkins
The external demands of small-sided games (SSGs) according to the positional role are currently unknown. Using a Catapult Minimax X3 5 Hz GPS, with a 100 Hz tri-axial accelerometer, we compared the accumulated tri-axial player workload per min (PLacc·min(-1)) during friendly youth match play (MP) (11 vs. 11) and SSGs (2 vs. 2, 3 vs. 3, and 4 vs. 4). Significant differences existed between all SSGs and MP for PLacc·min(-1) (F = 21.91, p < 0.001, η2 = 0.38), and individual X (F = 27.40, p < 0.001, η2 = 0...
June 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28700516/validity-of-real-time-data-generated-by-a-wearable-microtechnology-device
#15
Dan Weaving, Sarah Whitehead, Kevin Till, Ben Jones
Weaving, D, Whitehead, S, Till, K, and Jones, B. Validity of real-time data generated by a wearable microtechnology device. J Strength Cond Res 31(10): 2876-2879, 2017-The purpose of this study was to investigate the validity of global positioning system (GPS) and micro-electrical-mechanical-system (MEMS) data generated in real time through a dedicated receiver. Postsession data acted as the criterion as it is used to plan the volume and intensity of future training and is downloaded directly from the device...
October 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28636528/three-dimensional-reconstruction-of-energy-stores-for-jumping-in-planthoppers-and-froghoppers-from-confocal-laser-scanning-microscopy
#16
Igor Siwanowicz, Malcolm Burrows
Jumping in planthopper and froghopper insects is propelled by a catapult-like mechanism requiring mechanical storage of energy and its quick release to accelerate the hind legs rapidly. To understand the functional biomechanics involved in these challenging movements, the internal skeleton, tendons and muscles involved were reconstructed in 3-D from confocal scans in unprecedented detail. Energy to power jumping was generated by slow contractions of hind leg depressor muscles and then stored by bending specialised elements of the thoracic skeleton that are composites of the rubbery protein resilin sandwiched between layers of harder cuticle with air-filled tunnels reducing mass...
June 21, 2017: ELife
https://www.readbyqxmd.com/read/28536347/the-current-use-of-stem-cells-in-bladder-tissue-regeneration-and-bioengineering
#17
REVIEW
Yvonne Y Chan, Samantha K Sandlin, Eric A Kurzrock, Stephanie L Osborn
Many pathological processes including neurogenic bladder and malignancy necessitate bladder reconstruction, which is currently performed using intestinal tissue. The use of intestinal tissue, however, subjects patients to metabolic abnormalities, bladder stones, and other long-term sequelae, raising the need for a source of safe and reliable bladder tissue. Advancements in stem cell biology have catapulted stem cells to the center of many current tissue regeneration and bioengineering strategies. This review presents the recent advancements in the use of stem cells in bladder tissue bioengineering...
January 6, 2017: Biomedicines
https://www.readbyqxmd.com/read/28360121/prosthetic-model-but-not-stiffness-or-height-affects-the-metabolic-cost-of-running-for-athletes-with-unilateral-transtibial-amputations
#18
Owen N Beck, Paolo Taboga, Alena M Grabowski
Running-specific prostheses enable athletes with lower limb amputations to run by emulating the spring-like function of biological legs. Current prosthetic stiffness and height recommendations aim to mitigate kinematic asymmetries for athletes with unilateral transtibial amputations. However, it is unclear how different prosthetic configurations influence the biomechanics and metabolic cost of running. Consequently, we investigated how prosthetic model, stiffness, and height affect the biomechanics and metabolic cost of running...
July 1, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28293144/from-the-elastica-compass-to-the-elastica-catapult-an-essay-on-the-mechanics-of-soft-robot-arm
#19
C Armanini, F Dal Corso, D Misseroni, D Bigoni
An elastic rod is clamped at one end and has a dead load attached to the other (free) end. The rod is then slowly rotated using the clamp. When the load is smaller than the buckling value, the rod describes a continuous set of quasi-static forms and its end traces a (smooth, convex and simple) closed curve, which would be a circle if the rod were rigid. The closed curve is analytically determined through the integration of the Euler's elastica, so that for sufficiently small loads the mechanical system behaves as an 'elastica compass'...
February 2017: Proceedings. Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28276911/the-effect-of-physical-contact-on-changes-in-fatigue-markers-following-rugby-union-field-based-training
#20
Gregory Roe, Joshua Darrall-Jones, Kevin Till, Padraic Phibbs, Dale Read, Jonathon Weakley, Andrew Rock, Ben Jones
Repeated physical contact in rugby union is thought to contribute to post-match fatigue; however, no evidence exists on the effect of contact activity during field-based training on fatigue responses. Therefore, the purpose of this study was to examine the effect of contact during training on fatigue markers in rugby union players. Twenty academy rugby union players participated in the cross-over study. The magnitude of change in upper- and lower-body neuromuscular function (NMF), whole blood creatine kinase concentration [CK] and perception of well-being was assessed pre-training (baseline), immediately and 24 h post-training following contact and non-contact, field-based training...
July 2017: European Journal of Sport Science
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