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https://www.readbyqxmd.com/read/28640756/single-lead-f-wave-extraction-using-diffusion-geometry
#1
John Malik, Neil Reed, Chun-Li Wang, Hau-Tieng Wu
OBJECTIVE: A novel single-lead f-wave extraction algorithm based on the modern diffusion geometry data analysis framework is proposed. APPROACH: The algorithm is essentially an averaged beat subtraction algorithm, where the ventricular activity template is estimated by combining a newly designed metric, the 'diffusion distance', and the non-local Euclidean median based on the non-linear manifold setup. We coined the algorithm [Formula: see text]. MAIN RESULTS: Two simulation schemes are considered, and the new algorithm [Formula: see text] outperforms traditional algorithms, including the average beat subtraction, principal component analysis, and adaptive singular value cancellation, in different evaluation metrics with statistical significance...
June 22, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28628382/unpaking-runx3-functions-both-sides-of-the-coin
#2
Arun Kumar, Sandhya Sundaram, Suresh K Rayala, Ganesh Venkatraman
Post translational modifications of RUNX3 have been shown to play an important role in directing RUNX3 functions. In this review we highlight the phosphorylation dependent functions of RUNX3 as regulated by PAK1 and its implications on tumorigenesis.
June 19, 2017: Small GTPases
https://www.readbyqxmd.com/read/28624410/using-trial-eligibility-to-personalize-statin%C3%A2-therapy-appears-no-more-accurate%C3%A2-than-a-coin-flip-in-determining%C3%A2-high-risk-status
#3
EDITORIAL
Roger S Blumenthal, M Imran Aslam, J William McEvoy
No abstract text is available yet for this article.
June 9, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28620735/meningocele-manqu%C3%A3-a-comprehensive-review-of-this-enigmatic-finding-in-occult-spinal-dysraphism
#4
REVIEW
Cameron Schmidt, Ellie Bryant, Joe Iwanaga, Rod J Oskouian, W Jerry Oakes, R Shane Tubbs
The term meningocele manqué (MM) was coined in 1972 to describe a broad range of surgical findings characterized by intradural bands tethering neural structures to the dorsal dura. Over the following decades, reports continued to lump intradural tethering bands associated with a variety of comorbidities under the umbrella term MM. In more recent years, disorders previously called MM have been identified as embryologically distinct and were reclassified. While this sectioning continues, there remains a set of intradural tethering disorders for which no better term than MM exists...
June 15, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28616234/all-that-glitters-is-not-gold-a-case-of-lanthanum-carbonate-aspiration
#5
Suchitra Paranji, Neethi Paranji, Adam S Weltz
INTRODUCTION: Foreign body aspiration is a significant cause of morbidity and mortality in elderly hospitalized patients. These are typically small items that patients have access to, including small coins. CASE PRESENTATION: This is a case report of a 75-year-old man recently bedridden from a large hemispheric stroke with sudden onset of hoarseness, cough and dysphagia. A chest X-ray was obtained which showed a radiopaque coin-shaped foreign body, presumably a coin in his aerodigestive tract...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/28614029/attitudes-towards-attrition-among-uk-trainees-in-obstetrics-and-gynaecology
#6
Irene Gafson, Jane Currie, Sabrina O'Dwyer, Katherine Woolf, Ann Griffin
Physician dissatisfaction in the workplace has consequences for patient safety. Currently in the UK, 1 in 5 doctors who enter specialist training in obstetrics and gynaecology leave the programme before completion. Trainee attrition has implications for workforce planning, organization of health-care services and patient care. The authors conducted a survey of current trainees' and former trainees' views concerning attrition and 'peri-attrition' - a term coined to describe the trainee who has seriously considered leaving the specialty...
June 2, 2017: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/28613238/tracking-the-evolution-of-the-internet-of-things-concept-across-different-application-domains
#7
REVIEW
Jorge E Ibarra-Esquer, Félix F González-Navarro, Brenda L Flores-Rios, Larysa Burtseva, María A Astorga-Vargas
Both the idea and technology for connecting sensors and actuators to a network to remotely monitor and control physical systems have been known for many years and developed accordingly. However, a little more than a decade ago the concept of the Internet of Things (IoT) was coined and used to integrate such approaches into a common framework. Technology has been constantly evolving and so has the concept of the Internet of Things, incorporating new terminology appropriate to technological advances and different application domains...
June 14, 2017: Sensors
https://www.readbyqxmd.com/read/28612756/mobility-dependent-recombination-models-for-organic-solar-cells
#8
Alexander Wagenpfahl
Modern solar cell technologies are coined by the effort to enhance power conversion efficiencies. Limiting influences are manifold. Undoubtedly, the loss of electrical charge carriers, the charge carrier recombination, is one of the most prominent process which may lead to such limitations. In the field of organic solar cells with rather low charge carrier mobilities, the encounter of two charge carriers has turned out to be the limiting factor for charge carrier recombination. The recombination process strongly depends on the charge carrier mobilities...
June 14, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28606467/aryl-hydrocarbon-receptor-ahr-pioneer-member-of-the-basic-helix-loop-helix-per-arnt-sim-bhlh-pas-family-of-sensors-of-foreign-and-endogenous-signals
#9
REVIEW
Daniel W Nebert
The basic-helix-loop-helix Per-Arnt-Sim (bHLH/PAS) family comprises many transcription factors, found throughout all three kingdoms of life; bHLH/PAS members "sense" innumerable intracellular and extracellular "signals" - including endogenous compounds, foreign chemicals, gas molecules, redox potential, photons (light), gravity, heat, and osmotic pressure. These signals then initiate downstream signaling pathways involved in responding to that signal. The term "PAS", abbreviation for "Per-Arnt-Sim" was first coined in 1991...
June 9, 2017: Progress in Lipid Research
https://www.readbyqxmd.com/read/28606190/performance-associated-effect-variations-of-public-reporting-in-promoting-antibiotic-prescribing-practice-a-cluster-randomized-controlled-trial-in-primary-healthcare-settings
#10
Yuqing Tang, Chenxi Liu, Xinping Zhang
Aim To evaluate the variations in effect of public reporting in antibiotic prescribing practice among physicians with different performance in primary healthcare settings. BACKGROUND: Overprovision of antibiotics is a major public health concern. Public reporting has been adopted to encourage good antibiotic prescribing practices. However, which group, for instance, high, average or low antibiotic prescribers, accounted for antibiotic prescription reduction has not been fully understood...
June 13, 2017: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/28600632/dynamic-complexity-measures-and-entropy-paths-for-modelling-and-comparison-of-evolution-of-patients-with-drug-resistant-epileptic-encephalopathy-syndromes-drees
#11
Ricardo Zavala-Yoe, Ricardo A Ramirez-Mendoza
Epileptic encephalopathies (EE) is a term coined by the International League Against Epilepsy (ILAE) to refer to a group of epilepsies in which the ictal and interictal abnormalities may contribute to progressive cerebral dysfunction. Among them, two affect mainly children and are very difficult to deal with, Doose and Lennox-Gastaut syndromes, (DS and LGS, respectively). So far (Zavala-Yoe et al., J Integr Neurosci 15(2):205-223, 2015a and works of ours there), quantitative analysis of single case studies of EE have been performed...
June 9, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28600505/malnutrition-sarcopenia-syndrome-predicts-mortality-in-hospitalized-older-patients
#12
Xiaoyi Hu, Lei Zhang, Haozhong Wang, Qiukui Hao, Birong Dong, Ming Yang
A new term, malnutrition-sarcopenia syndrome (MSS), was recently coined to describe the clinical presentation of both malnutrition and sarcopenia. The aim of this study was to investigate the association between MSS and long-term mortality in older inpatients. We conducted a prospective study in acute geriatric wards of two local hospitals in China. Muscle mass and malnutrition were estimated by anthropometric measures and the Mini Nutritional Assessment (MNA). Of the 453 participants, 14 (3.1%) had sarcopenia with normal nutrition, 139 (30...
June 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28600139/change-of-target-volume-and-its-dosimetric-impact-during-the-course-of-accelerated-partial-breast-irradiation-using-intraoperative-multicatheter-interstitial-brachytherapy-after-open-cavity-surgery
#13
Ritu Raj Upreti, Ashwini Budrukkar, Udita Upreti, Shagun Misra, Tabassum Wadasadawala, Satish Kohle, Deepak D Deshpande
PURPOSE: To investigate the change of clinical target volume (CTV) and its dosimetric impact during the course of accelerated partial breast irradiation (APBI) using intraoperative multicatheter interstitial brachytherapy after open cavity surgery. METHODS AND MATERIALS: Twenty-two patients of APBI with intraoperative placement of catheters underwent computed tomography scans for the treatment planning before the first (CT1) and the last (CT2) treatment fraction...
June 6, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28599393/hepar-uterinum-a-history-of-ideas-on-fetal-nutrition
#14
Michael Obladen
The means of fetal nutrition has been debated for over two millennia, with the controversy of oral versus parenteral nutrition already in the Corpus Hippocraticum. In 1587 Aranzio rejected connections between maternal and fetal blood vessels, and coined the term "hepar uterinum" for the placenta. From the 16th to the 18th century, a fervent debate focused on the type and extent of connection between maternal and fetal vessels, which was finally settled by Hunter's injection experiment in 1774. But up to the middle of the 19th century, an important nutritive function was attributed to amniotic fluid...
May 24, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28597821/the-mycobiome-impact-on-health-and-disease-states
#15
Najla El-Jurdi, Mahmoud A Ghannoum
The term "microbiome" refers to microorganisms (microbiota) and their genomes (metagenome) coexisting with their hosts. Some researchers coined the term "second genome" to underscore the importance of the microbiota and its collective metagenome on their host's health and/or disease. It is now undeniable that the commensal fungal microorganisms, alongside the other components of the microbiota, play a central role in association with the human host. In recognition, projects were launched nationally and internationally to unify efforts to characterize the microbiome and elucidate the functional role of the microbiota and the mechanism(s) by which these organisms and their metabolites (metabolome) may affect health and disease states...
June 2017: Microbiology Spectrum
https://www.readbyqxmd.com/read/28595161/non-linear-actions-of-physiological-agents-finite-disarrangements-elicit-fitness-benefits
#16
REVIEW
Filip Sedlic, Zdenko Kovac
Finite disarrangements of important (vital) physiological agents and nutrients can induce plethora of beneficial effects, exceeding mere attenuation of the specific stress. Such response to disrupted homeostasis appears to be universally conserved among species. The underlying mechanism of improved fitness and longevity, when physiological agents act outside their normal range is similar to hormesis, a phenomenon whereby toxins elicit beneficial effects at low doses. Due to similarity with such non-linear response to toxins described with J-shaped curve, we have coined a new term "mirror J-shaped curves" for non-linear response to finite disarrangement of physiological agents...
May 18, 2017: Redox Biology
https://www.readbyqxmd.com/read/28594235/live-attenuated-auxotrophic-mutant-of-salmonella-typhimurium-expressing-immunogenic-ha1-protein-enhances-immunity-and-protective-efficacy-against-h1n1-influenza-virus-infection
#17
Nitin Machindra Kamble, Kim Je Hyoung, John Hwa Lee
AIM: To evaluate the efficacy of attenuated Salmonella typhimurium (JOL912) as a live bacterial vaccine vector. MATERIALS & METHODS: The JOL912 engineered to deliver HA1 protein from influenza A/Puerto Rico/8/1934 (H1N1; PR8) virus was coined as JOL1635 and further evaluated for immunogenicity and protective efficacy. RESULTS: The JOL1635 stably harbored the HA1 gene within pMMP65 plasmid with periplasmic expression and effective delivery of HA1 protein to RAW264...
June 8, 2017: Future Microbiology
https://www.readbyqxmd.com/read/28593763/high-performance-electroactive-polymer-actuators-based-on-ultrathick-ionic-polymer-metal-composites-with-nanodispersed-metal-electrodes
#18
Hyuck Sik Wang, Jaehyun Cho, Dae Seok Song, Jong Hyun Jang, Jae Young Jho, Jong Hyuk Park
Ionic polymer-metal composites (IPMCs) have been proposed as biomimetic actuators that are operable at low applied voltages. However, the bending strain and generating force of the IPMC actuators have generally exhibited a trade-off relationship, whereas simultaneous enhancement of both the qualities is required for their practical applications. Herein, a significant improvement in both the strain and force of the IPMC actuators is achieved by a facile approach, exploiting thickness-controlled ion-exchange membranes and nanodispersed metal electrodes...
June 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28583409/portopulmonary-hypertension-and-hepatorenal-syndrome-two-faces-of-the-same-coin
#19
REVIEW
Enrico Maria Zardi, Domenico Maria Zardi, Chiara Giorgi, Diana Chin, Aldo Dobrina
Portopulmonary hypertension and hepatorenal syndrome are both severe local hypertensive complications of liver cirrhosis and portal hypertension. Both are characterized by vasoconstrictive manifestations regarding pulmonary and renal vascular network, respectively. This review addresses the mechanisms underlying the development of vasoconstriction that leads to local vascular hypertension in the lung and in the kidney with the result of organ dysfunction. Potential therapeutic options are available for the management of these two syndromes as a bridge for liver transplantation; clinical efficacy depends in part on the time and rapidity of intervention and in part on how serious the chain of events is that has triggered the entire vasoconstrictive process...
June 2, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28581208/pigmentation-more-than-one-master
#20
Erna Magnúsdóttir
Vertebrate pigmentation is a process directed by various transcriptional regulators, that drive the specification of melanoblasts from neural crest cells, their proliferation and migration, and terminal differentiation into melanocytes, culminating in the generation of pigment and it's distribution to surrounding keratinocytes. The transcription factor MITF has been coined the "master regulator" of melanocyte development (reviewed in (Steingrímsson, Copeland and Jenkins, 2004)), as it drives both the specification and differentiation of melanocytes...
June 5, 2017: Pigment Cell & Melanoma Research
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