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https://www.readbyqxmd.com/read/29787832/a-comparative-study-of-quality-of-life-functional-and-bone-outcomes-in-osteogenesis-imperfecta-with-bisphosphonate-therapy-initiated-in-childhood-or-adulthood
#1
Andrew G Feehan, Margaret R Zacharin, Angelina S Lim, Peter J Simm
Bisphosphonates have been used for treatment of bone fragility disorders for over 25 years to increase bone mineral density (BMD). Anecdotally, bisphosphonate-treated Osteogenesis Imperfecta (OI) has a different trajectory to the natural history of untreated OI in terms of fracture incidence, quality of life and physical function, with minimal published evidence to support this clinical observation. This study describes functional outcomes of a cohort of adults with OI, stratified according to severity and treated with intravenous bisphosphonates as children...
May 19, 2018: Bone
https://www.readbyqxmd.com/read/29782595/the-clinical-value-of-xspect-ct-bone-versus-spect-ct-a-prospective-comparison-of-200-scans
#2
Iain Duncan, Nicholas Ingold
Purpose: To prospectively evaluate the clinical utility of xSPECT/CT Bone, a new reconstruction algorithm for single photon emission tomography (SPECT), and compare it with standard SPECT/CT reconstruction. Methods: Sequential reporting of SPECT/CT followed by xSPECT/CT images in 200 sequential cases commencing August 2015. Differences between the initial SPECT/CT and the final report (after xSPECT/CT reconstruction) were documented and analysed. 12-18 months after the initial study follow-up, clinical data was sought from a subset of cases in which xSPECT/CT changed the primary diagnosis and imaging correlation undertaken in all patients who subsequently had MRI or CT scans of the same region...
2018: European journal of hybrid imaging
https://www.readbyqxmd.com/read/29764447/efficacy-of-intra-articular-hypertonic-dextrose-prolotherapy-versus-normal-saline-for-knee-osteoarthritis-a-protocol-for-a-triple-blinded-randomized-controlled-trial
#3
Regina Wing Shan Sit, Ricky Wing Keung Wu, Kenneth Dean Reeves, David Rabago, Dicken Cheong Chun Chan, Benjamin Hon Kei Yip, Vincent Chi Ho Chung, Samuel Yeung Shan Wong
BACKGROUND: Knee Osteoarthritis (KOA) is a very common condition with prevalence rising with age. It is a major contributor to global disability and has a large socioeconomic burden worldwide. Conservative therapies have marginal effectiveness, and surgery is reserved for severe symptomatic KOA. Dextrose Prolotherapy (DPT) is an evidence-based injection-based therapy for chronic musculoskeletal conditions including KOA. The standard "whole joint" injection method includes intra-articular injection and multiple extra-articular injections at soft tissue bony attachments...
May 15, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29761353/trends-in-chronic-diseases-reported-by-refugees-originating-from-burma-resettling-to-the-united-states-from-camps-versus-urban-areas-during-2009-2016
#4
Barbara H Bardenheier, Christina R Phares, Diane Simpson, Edward Gregg, Pyone Cho, Stephen Benoit, Nina Marano
We examined changes in the prevalence of chronic health conditions among US-bound refugees originating from Burma resettling over 8 years by the type of living arrangement before resettlement, either in camps (Thailand) or in urban areas (Malaysia). Using data from the required overseas medical exam for 73,251 adult (≥ 18 years) refugees originating from Burma resettling to the United States during 2009-2016, we assessed average annual percent change (AAPC) in proportion ≥ 45 years and age- and sex-standardized prevalence of obesity, diabetes, hypertension, chronic obstructive pulmonary disease (COPD), and musculoskeletal disease, by camps versus urban areas...
May 15, 2018: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/29758110/can-quantitative-computed-tomography-detect-bone-morphological-changes-associated-with-catastrophic-proximal-sesamoid-bone-fracture-in-thoroughbred-racehorses
#5
E N Cresswell, S P McDonough, S E Palmer, C J Hernandez, H L Reesink
BACKGROUND: Fracture of the proximal sesamoid bones continues to be the most common fatal musculoskeletal injury in US racehorses. Identifying factors that influence fracture risk could lead to screening techniques to reduce catastrophic injury rates and improve animal welfare. OBJECTIVES: To identify morphological differences between proximal sesamoid bones of the contralateral limb of fracture and control horses and assess the feasibility of computed tomography (CT) to detect traits associated with proximal sesamoid bone fracture...
May 14, 2018: Equine Veterinary Journal
https://www.readbyqxmd.com/read/29734473/treatment-for-hepatitis-c-virus-associated-mixed-cryoglobulinaemia
#6
REVIEW
Nuria Montero, Alexandre Favà, Eva Rodriguez, Clara Barrios, Josep M Cruzado, Julio Pascual, Maria Jose Soler
BACKGROUND: Hepatitis C virus (HCV)-associated mixed cryoglobulinaemia is the manifestation of an inflammation of small and medium-sized vessels produced by a pathogenic IgM with rheumatoid factor activity generated by an expansion of B-cells. The immune complexes formed precipitate mainly in the skin, joints, kidneys or peripheral nerve fibres. Current therapeutic approaches are aimed at elimination of HCV infection, removal of cryoglobulins and also of the B-cell clonal expansions. The optimal treatment for it has not been established...
May 7, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29730631/effectiveness-of-extrinsic-feedback-for-management-of-non-specific-low-back-pain-a-systematic-review-protocol
#7
Daniel Cury Ribeiro, Aleksandra Katarzyna Mącznik, Stephan Milosavljevic, J Haxby Abbott
INTRODUCTION: Low back pain is the greatest cause of years lived with disability worldwide and is linked with high societal and economic burden. Neuromuscular control impairments are a common clinical presentation in patients with non-specific low back pain. Musculoskeletal physiotherapists commonly use feedback as a part of the management of low back disorders. This systematic review will aim to assess the effectiveness of extrinsic biofeedback for reducing pain, disability and recurrence of pain in patients with non-specific low back pain...
May 5, 2018: BMJ Open
https://www.readbyqxmd.com/read/29729818/long-term-patient-reported-outcomes-following-acetabular-fracture-fixation
#8
Diederik O Verbeek, Jelle P van der List, Camden M Tissue, David L Helfet
INTRODUCTION: Patient reported outcome scores may be the preferred method to assess clinical results following acetabular fracture fixation. However, in current acetabular fracture research, there is a scarcity of studies using these scores and long-term follow-up is lacking. The aim of this study is to describe long-term patient reported outcomes following acetabular fracture surgery and to evaluate the association between reduction quality and these outcome measures. METHODS: Patients who received operative fixation for acetabular fractures (1992-2012) were sent questionnaires (short musculoskeletal functional assessment (SMFA) function index and short form (SF)-12), which was returned by 106 patients (22%) (mean age 51 years, 74% male)...
April 27, 2018: Injury
https://www.readbyqxmd.com/read/29715520/-i-was-a-little-surprised-qualitative-insights-from-patients-enrolled-in-a-12-month-trial-comparing-opioids-to-non-opioid-medications-for-chronic-musculoskeletal-pain
#9
Marianne S Matthias, Melvin T Donaldson, Agnes C Jensen, Erin E Krebs
Chronic musculoskeletal pain is a major public health problem. Although opioid prescribing for chronic pain has increased dramatically since the 1990s, this practice has come under scrutiny because of increases in opioid-related harms and lack of evidence for long-term effectiveness. The Strategies for Prescribing Analgesics Comparative Effectiveness (SPACE) trial was a pragmatic 12-month randomized trial comparing benefits and harms of opioid versus non-opioid medications for chronic musculoskeletal pain. The current qualitative study was designed to better understand trial results by exploring patients' experiences, including perceptions of medications, experiences with the intervention, and whether expectations were met...
April 28, 2018: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29703804/opioids-versus-non-opioids-for-chronic-musculoskeletal-pain
#10
(no author information available yet)
No abstract text is available yet for this article.
April 26, 2018: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/29703242/an-ehealth-program-versus-a-standard-care-supervised-health-program-and-associated-health-outcomes-in-individuals-with-mobility-disability-study-protocol-for-a-randomized-controlled-trial
#11
Daniel Berglind, Gisela Nyberg, Mikaela Willmer, Margareta Persson, Michael Wells, Yvonne Forsell
BACKGROUND: Young adults with mobility disability (MD) are less likely to engage in regular physical activity (PA) compared with their able-bodied peers and inactive adults with a MD are more likely to report one or more chronic diseases compared to those who are physically active. Despite the vast amount of research published in the field of PA interventions over the past decades, little attention has been focused on interventions aiming to increase PA among individuals with MD. Thus, we propose to compare the effects of an eHealth program compared to a usual care supervised health program on levels of PA and other health behaviors...
April 27, 2018: Trials
https://www.readbyqxmd.com/read/29703193/patient-house-calls-in-attica-and-thessaloniki-greece-2005-2015-a-model-for-out-of-hospital-multispecialty-emergency-medicine
#12
George Theocharis, Spyridon G Barbas, Theodore Spiropoulos, Petroula E Stamouli, Dimitrios N Perdikis, Matthew E Falagas
BACKGROUND: The SOS-doctors are a network of physicians who perform house-call visits in the areas of Attica and Thessaloniki, Greece. METHODS: Patients requesting medical services by the SOS doctors during the period 1/1/2005 - 31/12/2015 were eligible for inclusion in this retrospective analysis. RESULTS: During this period 335, 212 home visits were performed. Females used this service more frequently compared to males (60.5% versus 39.5%)...
April 27, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29687966/spinal-manipulation-combined-with-laser-therapy-is-more-beneficial-than-laser-therapy-alone-in-chronic-non-specific-low-back-pain-a-randomized-controlled-study
#13
Gopal N Subash Chandra Bose, Walid Kamal, Shanmugananth Es, Siddhart Joshi, Parth Trivedi
BACKGROUND: Low back pain (LBP) is a common musculoskeletal disorder causing pain and disability in most of the countries. In recent years, new approaches such as Spinal manipulation and laser therapy have been considered as an alternative to conventional exercise and also found contradicting results in terms of its effectiveness. AIM: A study to compare the combined effects of spinal manipulation, Laser and exercise versus Laser and exercise alone in chronic non-specific low back pain (cnLBP)...
April 24, 2018: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29683858/the-effect-of-booster-seat-use-on-pediatric-injuries-in-motor-vehicle-frontal-crashes
#14
Sean Caskey, Joshua Hammond, Jeffery Peck, Matthew Sardelli, Theresa Atkinson
BACKGROUND: Motor vehicle crashes are a significant source of pediatric mortality and morbidity. Studies indicate that booster seats significantly improve seat belt fit for children who have not attained a height of 145 cm (4' 9"). This study examined injuries occurring in booster age children up to age 12, as the majority of children do not attain 145 cm until this age. The purpose of the study was to identify differences in injuries due to the type of restraint used, with attention to musculoskeletal injuries...
April 20, 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29674367/trends-in-diagnosis-specific-work-disability-before-and-after-ischaemic-heart-disease-a-nationwide-population-based-cohort-study-in-sweden
#15
Jenni Ervasti, Marianna Virtanen, Tea Lallukka, Emilie Friberg, Ellenor Mittendorfer-Rutz, Erik Lundström, Kristina Alexanderson
OBJECTIVES: We examined trends of diagnosis-specific work disability before and after ischaemic heart disease (IHD). DESIGN: Participants were followed 4 years before and 4 years after an IHD event for diagnosis-specific work disability (sickness absence and disability pension). SETTING AND PARTICIPANTS: A Swedish population-based cohort study using register data on all individuals aged 25-60 years, living in Sweden, and who suffered their first IHD event in 2006-2008 (n=23 971) was conducted...
April 19, 2018: BMJ Open
https://www.readbyqxmd.com/read/29671032/sitting-versus-standing-makes-a-difference-in-musculoskeletal-discomfort-and-postural-load-for-surgeons-performing-vaginal-surgery
#16
Ruchira Singh, Ladin A Yurteri-Kaplan, Melissa M Morrow, Amy L Weaver, Michaela E McGree, Xinhui Zhu, Victor L Paquet, John B Gebhart, Susan Hallbeck
INTRODUCTION AND HYPOTHESIS: We compared musculoskeletal discomfort and postural load among surgeons in sitting and standing positions during vaginal surgery. MATERIALS AND METHODS: Assessment of discomfort and posture of the primary surgeons in both positions was performed at two institutions. The primary outcome was an increase in body discomfort score after surgery as determined from subjective responses using validated tools. The secondary outcome was the percentage of time spent in awkward body postures measured objectively and stratified into awkward postures for neck, trunk, and bilateral shoulder angles...
April 18, 2018: International Urogynecology Journal
https://www.readbyqxmd.com/read/29669259/anatomy-learning-from-prosected-cadaveric-specimens-versus-three-dimensional-software-a-comparative-study-of-upper-limb-anatomy
#17
Vasileios Mitrousias, Sokratis E Varitimidis, Michael E Hantes, Konstantinos N Malizos, Dimitrios L Arvanitis, Aristeidis H Zibis
INTRODUCTION: modern, three-dimensional (3D) anatomy software is a promising teaching method, though few studies examine its effectiveness on upper limb and musculoskeletal anatomy learning. The purpose of this study is to investigate which method is associated with a better outcome, as assessed by students' performance on examinations, when comparing learning with prosections to the use of 3D software. MATERIALS AND METHODS: two groups of undergraduate, first-year medical students without previous knowledge of anatomy were compared...
April 15, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/29657826/heel-impact-forces-during-barefoot-versus-minimally-shod-walking-among-tarahumara-subsistence-farmers-and-urban-americans
#18
Ian J Wallace, Elizabeth Koch, Nicholas B Holowka, Daniel E Lieberman
Despite substantial recent interest in walking barefoot and in minimal footwear, little is known about potential differences in walking biomechanics when unshod versus minimally shod. To test the hypothesis that heel impact forces are similar during barefoot and minimally shod walking, we analysed ground reaction forces recorded in both conditions with a pedography platform among indigenous subsistence farmers, the Tarahumara of Mexico, who habitually wear minimal sandals, as well as among urban Americans wearing commercially available minimal sandals...
March 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29656303/spondylodiscitis-following-endovascular-abdominal-aortic-aneurysm-repair-imaging-perspectives-from-a-single-centre-s-experience
#19
Ramin Mandegaran, Christopher S W Tang, Erlick A C Pereira, Ali Zavareh
OBJECTIVE: Very few reports have previously described spondylodiscitis as a potential complication of endovascular aortic aneurysm repair (EVAR). We present to our knowledge the first case series of spondylodiscitis following EVAR based on our institution's experience over an 11-year period. Particular attention is paid to the key imaging features and challenges encountered when performing spinal imaging in this complex patient group. MATERIALS AND METHODS: Of 1,847 patients who underwent EVAR at our institution between January 2006 and January 2017, a total of 9 patients were identified with imaging features of spondylodiscitis (0...
April 14, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29653381/swelling-of-fiber-reinforced-soft-tissues-is-affected-by-fiber-orientation-fiber-stiffness-and-lamella-structure
#20
Bo Yang, Grace D O'Connell
Native and engineered fiber-reinforced tissues are composites comprised of stiff collagen fibers embedded within an extrafibrillar matrix that is capable of swelling by absorbing water molecules. Tissue swelling is important for understanding stress distributions between collagen fibers and extrafibrillar matrix, as well as for understanding mechanisms of tissue failure. The swelling behavior of fiber-reinforced tissues in the musculoskeletal system has been largely attributed to the glycosaminoglycan content...
April 3, 2018: Journal of the Mechanical Behavior of Biomedical Materials
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