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https://www.readbyqxmd.com/read/28194714/is-limb-salvage-with-microwave-induced-hyperthermia-better-than-amputation-for-osteosarcoma-of-the-distal-tibia
#1
Kang Han, Peiye Dang, Na Bian, Xiang Chen, Tongtao Yang, QingYu Fan, Yong Zhou, Tingbao Zhao, Pingshan Wang
BACKGROUND: Amputation has been the standard surgical treatment for distal tibia osteosarcoma owing to its unique anatomic features. Preliminary research suggested that microwave-induced hyperthermia may have a role in treating osteosarcoma in some locations of the body (such as the pelvis), but to our knowledge, no comparative study has evaluated its efficacy in a difficult-to-treat location like the distal tibia. QUESTIONS: Does microwave-induced hyperthermia result in (1) improved survival, (2) decreased local recurrence, (3) improved Musculoskeletal Tumor Society (MSTS) scores, or (4) fewer complications than amputation in patients with a distal tibial osteosarcoma? METHODS: Between 2000 and 2015, we treated 79 patients for a distal tibia osteosarcoma without metastases...
February 13, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28191312/mapping-eq-5d-utilities-to-gbd-2010-and-gbd-2013-disability-weights-results-of-two-pilot-studies-in-belgium
#2
C Maertens de Noordhout, B Devleesschauwer, L Gielens, M H D Plasmans, J A Haagsma, N Speybroeck
BACKGROUND: Utilities and disability weights (DWs) are metrics used for calculating Quality-Adjusted Life Years and Disability-Adjusted Life Years (DALYs), respectively. Utilities can be obtained with multi-attribute instruments such as the EuroQol 5 dimensions questionnaire (EQ-5D). In 2010 and 2013, Salomon et al. proposed a set of DWs for 220 and 183 health states, respectively. The objective of this study is to develop an approach for mapping EQ-5D utilities to existing GBD 2010 and GBD 2013 DWs, allowing to predict new GBD 2010/2013 DWs based on EQ-5D utilities...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28178024/the-effects-of-curcuminoids-on-musculoskeletal-pain-a-systematic-review
#3
Andrew Gaffey, Helen Slater, Kylie Porritt, Jared M Campbell
BACKGROUND: Western countries are increasingly using complementary and alternative medicine (CAM) to assist with relieving ailments. Turmeric, from the ginger family Zingiberaceae, has a history of use for medicinal purposes. The polyphenols found in turmeric (curcuminoids) have demonstrated anti-inflammatory and pain relieving properties. With the use of CAMs increasing, it is important for the effectiveness of curcuminoids to be established. OBJECTIVES: To identify the effectiveness of the use of curcuminoids for the amelioration of musculoskeletal pain...
February 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28167373/extraskeletal-osteosarcoma-a-european-musculoskeletal-oncology-society-study-on-266-patients
#4
A Longhi, S S Bielack, R Grimer, J Whelan, R Windhager, A Leithner, A Gronchi, D Biau, P Jutte, A H Krieg, F M Klenke, G Grignani, D M Donati, R Capanna, J Casanova, C Gerrand, G Bisogno, S Hecker-Nolting, M De Lisa, L D'Ambrosio, M Willegger, G Scoccianti, S Ferrari
PURPOSE: Prognosis of extraskeletal osteosarcoma (ESOS) is reported to be poorer than that of skeletal osteosarcoma. This multicenter retrospective study aimed to evaluate factors influencing ESOS prognosis. PATIENTS AND METHODS: Members of the European Musculoskeletal Oncology Society (EMSOS) submitted institutional data on patients with ESOS. RESULTS: Data from 274 patients treated from 1981 to 2014 were collected from 16 EMSOS centres; 266 patients were eligible...
February 3, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28158152/effects-of-dry-needling-on-spinal-mobility-and-trigger-points-in-patients-with-fibromyalgia-syndrome
#5
Adelaida Maria Castro-Sanchez, Hector Garcia-Lopez, Guillermo A Mataran-Penarrocha, Manuel Fernandez-Sanchez, Cayetano Fernandez-Sola, Jose Granero-Molina, Maria Encarnacion Aguilar-Ferrandiz
BACKGROUND: The etiology of fibromyalgia syndrome (FMS) is inconclusive, but central mechanisms are well accepted for this pain condition. Myofascial pain syndrome (MPS) is one of the most common musculoskeletal pain diseases and is characterized by myofascial trigger points (MTrPs). It has been suggest that MTrPs have an important factor in the genesis of FMS. OBJECTIVE: The purpose of the current randomized clinical trial was to compare the effectiveness of dry needling versus cross tape on spinal mobility and MTrPs in spinal muscles in patients with FMS...
February 2017: Pain Physician
https://www.readbyqxmd.com/read/28148701/need-for-improvement-in-current-treatment-of-psoriatic-arthritis-study-of-an-outpatient-clinic-population
#6
Brigitte Michelsen, Andreas P Diamantopoulos, Hege Kilander Høiberg, Dag Magnar Soldal, Arthur Kavanaugh, Glenn Haugeberg
OBJECTIVE: To explore the burden of skin, joint, and entheses manifestations in a representative psoriatic arthritis (PsA) outpatient cohort in the biologic treatment era. METHODS: This was a cross-sectional study of 141 PsA outpatients fulfilling the ClASsification for Psoriatic ARthritis (CASPAR) criteria and examined between January 2013 and May 2014. Selected disease activity measures were explored including Disease Activity index for PSoriatic Arthritis (DAPSA), Composite Psoriatic Disease Activity Index (CPDAI), Psoriatic Arthritis Disease Activity Score (PASDAS), Disease Activity Score for 28 joints (DAS28), Simplified Disease Activity Index (SDAI), and Psoriasis Area Severity Index (PASI)...
February 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28126693/differences-in-knee-adduction-moment-between-healthy-subjects-and-patients-with-osteoarthritis-depend-on-the-knee-axis-definition
#7
S Meireles, F De Groote, S Van Rossom, S Verschueren, I Jonkers
OBJECTIVE: This study, firstly, investigates the effect of using an anatomical versus a functional axis of rotation (FAR) on knee adduction moment (KAM) in healthy subjects and patients with knee osteoarthritis (KOA). Secondly, this study reports KAM for models with FAR calculated using weight-bearing and non-weight-bearing motion. DESIGN: Three musculoskeletal models were created using OpenSim with different knee axis of rotation (AR): transepicondylar axis (TEA); FAR calculated based on SARA algorithm using a weight-bearing motion (wFAR) and a non-weight-bearing motion (nwFAR)...
January 19, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28119823/pilot-study-of-the-safety-and-effect-of-adalimumab-on-pain-physical-function-and-musculoskeletal-disease-in-mucopolysaccharidosis-types-i-and-ii
#8
Lynda E Polgreen, Alicia Kunin-Batson, Kyle Rudser, Richard K Vehe, Jeanine J Utz, Chester B Whitley, Patricia Dickson
Mucopolysaccharidosis I and II are lysosomal storage disorders that, despite treatment with hematopoietic cell transplantation (HCT) and/or enzyme replacement therapy (ERT), continue to cause significant skeletal abnormalities leading to pain, stiffness, physical dysfunction, and short stature. Tumor necrosis factor - alpha (TNF-α) is elevated in individuals with MPS I and II and associated with pain and physical dysfunction. Therefore, we evaluated the safety and effects of the TNF-α inhibitor adalimumab in patients with MPS I and II in a 32-week, randomized, double blind, placebo-controlled, crossover study of adalimumab at a dose of 20 mg (weight 15-<30 kg) or 40 mg (weight ≥ 30 kg) administered subcutaneously every other week or saline placebo for 16 weeks...
March 2017: Molecular Genetics and Metabolism Reports
https://www.readbyqxmd.com/read/28111089/biological-therapy-and-development-of-neoplastic-disease-in-patients-with-juvenile-rheumatic-disease-a-systematic-review
#9
Vanessa Patricia L Pereira, Teresa Cristina Martins Vicente Robazzi
Juvenile rheumatic diseases affect the musculoskeletal system and begin before the age of 18. These conditions have varied, identifiable or unknown etiologies, but those of an autoimmune inflammatory nature have been associated with an increased risk of development of cancer, regardless of treatment. This study aims to assess, through a systematic review of the literature according to Prisma (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) quality criteria, the risk of cancer in patients with juvenile rheumatic disease, and its association with biological agents...
October 29, 2016: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28106306/acupuncture-and-electro-acupuncture-for-people-diagnosed-with-subacromial-pain-syndrome-a-multicentre-randomized-trial
#10
J Lewis, J Sim, P Barlas
BACKGROUND: Musculoskeletal disorders have been identified globally as the second most common healthcare problem for 'years lived with disability', and of these shoulder conditions are amongst the most common, frequently associated with substantial pain and morbidity. Exercise and acupuncture are often provided as initial treatments for musculoskeletal shoulder conditions but their clinical effectiveness is uncertain. This study compared group exercise with group exercise plus either acupuncture or electro-acupuncture in patients with subacromial pain syndrome...
January 20, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28096255/sheppheartcabg-trial-comprehensive-early-rehabilitation-after-coronary-artery-bypass-grafting-a-protocol-for-a-randomised-clinical-trial
#11
Ida Elisabeth Højskov, Philip Moons, Niels Viggo Hansen, Søren La Cour, Peter Skov Olsen, Christian Gluud, Per Winkel, Jane Lindschou, Lau Caspar Thygesen, Ingrid Egerod, Selina Kikkenborg Berg
INTRODUCTION: Patients undergoing coronary artery bypass graft surgery often experience a range of symptoms. Studies indicate that non-pharmacological interventions such as exercise training and psychoeducation have a positive physiological and psychological effect in early outpatient rehabilitation. The SheppHeartCABG trial will investigate the effect of early comprehensive rehabilitation in early phase rehabilitation versus usual care. The aim of this paper is to present the protocol for the SheppHeartCABG trial...
January 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28092340/decompression-surgery-alone-versus-decompression-plus-fusion-in-symptomatic-lumbar-spinal-stenosis-a-swiss-prospective-multi-center-cohort-study-with-3-years-of-follow-up
#12
Nils H Ulrich, Jakob M Burgstaller, Giuseppe Pichierri, Maria M Wertli, Mazda Farshad, François Porchet, Johann Steurer, Ulrike Held
STUDY DESIGN: Retrospective analysis of a prospective, multicenter cohort study. OBJECTIVE: To estimate the added effect of surgical fusion as compared to decompression surgery alone in symptomatic lumbar spinal stenosis patients with spondylolisthesis. SUMMARY OF BACKGROUND DATA: The optimal surgical management of lumbar spinal stenosis patients with spondylolisthesis remains controversial. METHODS: Patients of the LSOS with confirmed DLSS and spondylolisthesis were enrolled in this study...
January 13, 2017: Spine
https://www.readbyqxmd.com/read/28090449/ultrashort-time-to-echo-magnetic-resonance-techniques-for-the-musculoskeletal-system
#13
REVIEW
Palanan Siriwanarangsun, Sheronda Statum, Reni Biswas, Won C Bae, Christine B Chung
Magnetic resonance (MR) imaging has been widely implemented as a non-invasive modality to investigate musculoskeletal (MSK) tissue disease, injury, and pathology. Advancements in MR sequences provide not only enhanced morphologic contrast for soft tissues, but also quantitative biochemical evaluation. Ultrashort time to echo (UTE) sequence, in particular, enables novel morphologic and quantitative evaluation of previously unseen MSK tissues. By using short minimum echo times (TE) below 1 msec, the UTE sequence can unveil short T2 properties of tissues including the deepest layers of the articular cartilage, cartilaginous endplate at the discovertebral junction, the meniscus, and the cortical bone...
December 2016: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28079844/serum-interleukin-6-in-systemic-sclerosis-and-its-correlation-with-disease-parameters-and-cardiopulmonary-involvement
#14
Rasha A Abdel-Magied, Shereen R Kamel, Azza Farag Said, Hazem M Ali, Ehab A Abdel Gawad, Mahmoud M Moussa
OBJECTIVE: To assess serum interleukin-6 (IL-6)level in patients with systemic sclerosis (SSc) and its correlations with European Scleroderma Study Group activity score (EUSTAR), Scleroderma Assessment Questionnaire (SAQ), disability index and cardiopulmonary involvement. METHODS: Twenty SSc patients and 10 matched healthy controls were included. Serum IL-6 was measured in patients and controls. Disease activity, status,and disability were assessed.Cardiopulmonary involvement was evaluated by pulmonary function tests (PFTs), six minute walk test, echocardiography, and high resolution computed tomography (HRCT) of chest...
December 23, 2016: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases: Official Journal of WASOG
https://www.readbyqxmd.com/read/28060526/effects-of-dual-monitor-computer-work-versus-laptop-work-on-cervical-muscular-and-proprioceptive-characteristics-of-males-and-females
#15
Amanda M Farias Zuniga, Julie N Côté
OBJECTIVE: The effects of performing a 90-minute computer task with a laptop versus a dual monitor desktop workstation were investigated in healthy young male and female adults. BACKGROUND: Work-related musculoskeletal disorders are common among computer (especially female) users. Laptops have surpassed desktop computer sales, and working with multiple monitors has also become popular. However, few studies have provided objective evidence on how they affect the musculoskeletal system in both genders...
December 1, 2016: Human Factors
https://www.readbyqxmd.com/read/28050816/-knuckle-cracking-can-blinded-observers-detect-changes-with-physical-examination-and-sonography
#16
Robert D Boutin, Anuj P Netto, David Nakamura, Cyrus Bateni, Robert M Szabo, Michael Cronan, Brent Foster, William R Barfield, J Anthony Seibert, Abhijit J Chaudhari
BACKGROUND: Voluntary knuckle cracking is a common habit, with a reported prevalence of 25% to 45%. Habitual knuckle cracking also is a frequent source of questions for physicians, and the largest study to date reported an association with functional hand impairments. QUESTIONS/PURPOSES: (1) When compared with subjects who are not habitual knuckle crackers, do habitual knuckle crackers have greater QuickDASH scores, swelling, weakness, joint laxity, or ROM? (2) In subjects who crack their knuckles, does cracking immediately increase ROM? (3) What are the characteristic sonographic findings in joints that crack? METHODS: A prospective, institutional review board-approved study was performed on 400 metacarpophalangeal joints (MPJs) in 40 asymptomatic adult subjects...
January 3, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28045805/predictors-of-depression-and-musculoskeletal-disorder-related-work-disability-among-young-middle-aged-and-aging-employees
#17
Jenni Ervasti, Pauliina Mattila-Holappa, Matti Joensuu, Jaana Pentti, Tea Lallukka, Mika Kivimäki, Jussi Vahtera, Marianna Virtanen
OBJECTIVE: The aim of this study was to investigate the level and predictors of work disability in different age groups. METHODS: We followed young (18 to 34 years), middle-aged (35 to 50 years), and aging (>50 years) employees (n = 70,417) for 7 years (2005 to 2011) for all-cause and cause-specific work disability (sickness absence and disability pension). Using negative binomial regression, we obtained both relative risk estimates and absolute rates, that is, days of work disability per person-year...
January 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28029069/effectiveness-of-osteopathic-manipulative-treatment-versus-osteopathy-in-the-cranial-field-in-temporomandibular-disorders-a-pilot-study
#18
Christina Gesslbauer, Nadja Vavti, Mohammad Keilani, Michael Mickel, Richard Crevenna
PURPOSE: Temporomandibular disorders are a common musculoskeletal condition causing severe pain, physical and psychological disability. The effect and evidence of osteopathic manipulative treatment and osteopathy in the cranial field is scarce and their use are controversial. The purpose of this pilot study was to evaluate the effectiveness of osteopathic manipulative treatment and osteopathy in the cranial field in temporomandibular disorders. METHODS: A randomized clinical trial in patients with temporomandibular disorders was performed...
December 28, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27998042/ultrasound-features-of-the-posterior-tibialis-tendon-and-peroneus-brevis-tendon-entheses-a-comparison-study-between-healthy-adults-and-inflammatory-arthritis
#19
Ian M Ward, Eugene Kissin, Gurjit Kaeley, Joshua N Scott, Michelle Newkirk, Bernard A Hildebrand, Josh Lospinoso, Minna J Kohler, Jay B Higgs
OBJECTIVES: Limited literature exists on the sonographic appearance of the posterior tibialis (PTT) and the peroneus brevis (PBT) tendon entheses. We determined the anatomic features and best imaging techniques of normal PTT and PBT using musculoskeletal ultrasound and compared these findings to subjects with inflammatory arthritis. METHODS: Adult subjects were enrolled as: healthy controls (HC), rheumatoid arthritis (RA), and spondyloarthropathy (SpA). Bilateral PTT and PBT entheses were imaged longitudinally, comparing two angles of insonation: perpendicular to the skin surface and 45˚ cephalad...
December 20, 2016: Arthritis Care & Research
https://www.readbyqxmd.com/read/27995604/exercise-therapy-for-chronic-fatigue-syndrome
#20
REVIEW
Lillebeth Larun, Kjetil G Brurberg, Jan Odgaard-Jensen, Jonathan R Price
BACKGROUND: Chronic fatigue syndrome (CFS) is characterised by persistent, medically unexplained fatigue, as well as symptoms such as musculoskeletal pain, sleep disturbance, headaches and impaired concentration and short-term memory. CFS presents as a common, debilitating and serious health problem. Treatment may include physical interventions, such as exercise therapy, which was last reviewed in 2004. OBJECTIVES: The objective of this review was to determine the effects of exercise therapy (ET) for patients with CFS as compared with any other intervention or control...
20, 2016: Cochrane Database of Systematic Reviews
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