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https://www.readbyqxmd.com/read/28523033/low-energy-versus-middle-energy-extracorporeal-shockwave-therapy-for-the-treatment-of-snapping-scapula-bursitis
#1
Nihat Acar
OBJECTIVE: Extracorporeal shockwave therapy (ESWT) has been used successfully in treatment of musculoskeletal disorders. Our objective was to assess the effectiveness of low versus middle-energy ESWT on snapping scapula bursitis. METHODS: Thirty-five patients, divided into two groups, group (L), received low-energy ESWT, group (M) received middle-energy ESWT. Groups were evaluated at 1,3,6 and 12 months using the Visual Analogue Scale (VAS), the Constant-Murley scoring (CMS) and the Roles and Maudsley criteria...
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28500776/analysis-of-national-pharmacovigilance-data-associated-with-statin-use-in-korea-adverse-drug-reactions-with-statins
#2
Hyunah Kim, Namhyo Kim, Da Hee Lee, Hun-Sung Kim
The aim of this study was to evaluate clinical manifestations, age distribution and risk factors of adverse drug reactions (ADRs) of statins. Korean Adverse Event Reporting System (KAERS) database records (July 2009 - June 2014) on statin-treated adults were used. ADRs classified as "certain," "probable" and "possible" based on the WHO-Uppsala Monitoring Centre criteria were analysed. The frequency of ADRs was compared between adults (18-64 years) and older people (age ≥ 65 years) groups. In total, 2161 ADRs from 1690 patients (579, 34...
May 13, 2017: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28492695/joint-assessment-in-von-willebrand-disease-validation-of-the-haemophilia-joint-health-score-and-haemophilia-activities-list
#3
Karin P M van Galen, Merel A Timmer, Piet de Kleijn, Kathelijn Fischer, Wouter Foppen, Roger E G Schutgens, Jeroen Eikenboom, Karina Meijer, Marjon H Cnossen, Karin Fijnvandraat, Johanna G van der Bom, Britta A P Laros-van Gorkom, Frank W G Leebeek, Eveline P Mauser-Bunschoten
Assessment of clinical outcome after joint bleeding is essential to identify joint damage and optimise treatment, to prevent disability. However, disease-specific tools to assess the musculoskeletal status in patients with von Willebrand disease (VWD) are lacking. We aimed to determine validity and reliability of the Haemophilia Joint Health Score (HJHS) and Haemophilia Activities List (HAL) in patients with Von Willebrand disease (VWD). Ninety-six patients with VWD were included (mean age 46 years) of whom 27 had more than five documented joint bleeds...
May 11, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/28486337/hypertrophic-effects-of-concentric-versus-eccentric-muscle-actions-a-systematic-review-and-meta-analysis
#4
Brad J Schoenfeld, Dan Ogborn, Andrew D Vigotsky, Martino Franchi, James W Krieger
Controversy exists as to whether different dynamic muscle actions produce divergent hypertrophic responses. The purpose of this paper was to conduct a systematic review and meta-analysis of randomized controlled trials comparing the hypertrophic effects of concentric versus eccentric training in healthy adults following regimented resistance training (RT). Studies were deemed eligible for inclusion if they met the following criteria: 1) were an experimental trial published in an English-language refereed journal; 2) directly compared concentric and eccentric actions without the use of external implements (i...
May 5, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28484791/varus-femoral-and-tibial-coronal-alignments-result-in-different-kinematics-and-kinetics-after-total-knee-arthroplasty
#5
Mutsumi Watanabe, Shinichi Kuriyama, Shinichiro Nakamura, Yoshihisa Tanaka, Kohei Nishitani, Moritoshi Furu, Hiromu Ito, Shuichi Matsuda
PURPOSE: Abnormal knee motion under various conditions has been described after total knee arthroplasty (TKA). However, differences in kinematics and kinetics of knees with varus femoral versus varus tibial alignment have not been evaluated. It was hypothesized that varus femoral and tibial alignments have the same impact on knee motion. METHODS: A musculoskeletal computer simulation was used. Femoral and tibial alignment in the coronal plane was each varied from neutral to 5° of varus in 1° increments...
May 8, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28473423/efficacy-and-safety-of-abatacept-a-t-cell-modulator-in-a-randomised-double-blind-placebo-controlled-phase-iii-study-in-psoriatic-arthritis
#6
Philip J Mease, Alice B Gottlieb, Désirée van der Heijde, Oliver FitzGerald, Alyssa Johnsen, Marleen Nys, Subhashis Banerjee, Dafna D Gladman
OBJECTIVES: To assess the efficacy and safety of abatacept, a selective T-cell costimulation modulator, in a phase III study in psoriatic arthritis (PsA). METHODS: This study randomised patients (1:1) with active PsA (~60% with prior exposure to a tumour necrosis factor inhibitor) to blinded weekly subcutaneous abatacept 125 mg (n=213) or placebo (n=211) for 24 weeks, followed by open-label subcutaneous abatacept. Patients without ≥20% improvement in joint counts at week 16 were switched to open-label abatacept...
May 4, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28464548/comparison-of-physical-examination-performance-of-medical-students-trained-by-musculoskeletal-versus-non-musculoskeletal-specialists
#7
Luciano Melo, Leslie Schrieber, Jillian Eyles, Leticia A Deveza, Sarah R F Meneses, David J Hunter
AIM: To compare the musculoskeletal (MSK) physical examination skills, knowledge acquisition and performance of first-year medical students trained by MSK specialist tutors to students trained by non-MSK specialist tutors, after a 6-week MSK physical examination tutorial program. METHODS: Twenty-first year medical students took part in the study. They were recruited into two groups, according to their exposure to either an MSK specialist or a non-MSK specialist tutor during their 6-week MSK training block...
May 2, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28462604/desmoplastic-fibroma-versus-soft-tissue-desmoid-tumour-of-forearm-a-case-series-of-diagnosis-surgical-approach-and-outcome
#8
K Jamshidi, A Bagherifard, A Mirzaei
We report a case series of aggressive fibromatosis of the forearm and discuss the differentiation criteria of overlapped intra- or extra-osseous origin of aggressive fibromatosis, surgical approach, and outcome. Ten cases of aggressive fibromatosis of the forearm were evaluated. When there was no involvement of vital adjacent structures, such as nerves, vessels, and tendons, en-bloc excision was performed for the removal of the soft-tissue mass. Bone involvement was observed in nine cases. Intercalary allograft was performed whenever one of the forearm bones was involved (six cases), while extensive curettage was used if both forearm bones were affected (three cases)...
April 1, 2017: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/28453453/whole-body-vibration-versus-magnetic-therapy-on-bone-mineral-density-in-elderly-osteoporotic-individuals
#9
Alsayed Abd Elhameed Shanb, Enas Fawzy Youssef, Qassim Ibrahim Muaidi, Abdullah Ahmed Alothman
BACKGROUND: Osteoporosis, which develops gradually and progresses without significant signs and symptoms, is one of the most common musculoskeletal conditions associated with aging. OBJECTIVES: To evaluate the effects of whole body vibration (WBV) or magnetic therapy in addition to standard pharmacological treatment on bone mineral density (BMD) in elderly individuals being treated for osteoporosis. METHODS: Eighty-five participants, 60-75 years of age, were randomly divided into three groups...
April 14, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28450779/clinical-differences-among-the-elderly-admitted-to-the-emergency-department-for-accidental-or-unexplained-falls-and-syncope
#10
Giuseppe Pasqualetti, Valeria Calsolaro, Giacomo Bini, Umberto Dell'Agnello, Marco Tuccori, Alessandra Marino, Alice Capogrosso-Sansone, Martina Rafanelli, Massimo Santini, Eugenio Orsitto, Andrea Ungar, Corrado Blandizzi, Fabio Monzani
It is difficult to distinguish unexplained falls (UFs) from accidental falls (AFs) or syncope in older people. This study was designed to compare patients referred to the emergency department (ED) for AFs, UFs or syncope. Data from a longitudinal study on adverse drug events diagnosed at the ED (ANCESTRAL-ED) in older people were analyzed in order to select cases of AF, syncope, or UF. A total of 724 patients (median age: 81.0 [65-105] years, 66.3% female) were consecutively admitted to the ED (403 AF, 210 syncope, and 111 UF)...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28444695/exercise-therapy-for-chronic-fatigue-syndrome
#11
REVIEW
Lillebeth Larun, Kjetil G Brurberg, Jan Odgaard-Jensen, Jonathan R Price
BACKGROUND: Chronic fatigue syndrome (CFS) is characterised by persistent, medically unexplained fatigue, as well as symptoms such as musculoskeletal pain, sleep disturbance, headaches and impaired concentration and short-term memory. CFS presents as a common, debilitating and serious health problem. Treatment may include physical interventions, such as exercise therapy, which was last reviewed in 2004. OBJECTIVES: The objective of this review was to determine the effects of exercise therapy (ET) for patients with CFS as compared with any other intervention or control...
April 25, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28441951/minimal-clinically-important-difference-for-the-6-min-walk-test-literature-review-and-application-to-morquio-a-syndrome
#12
REVIEW
Rudolf Schrover, Kathryn Evans, Roberto Giugliani, Ian Noble, Kaustuv Bhattacharya
Morquio A syndrome is an ultra-rare, inherited lysosomal storage disorder associated with progressive, multi-systemic clinical impairments, causing gradual loss of functional capacity and endurance, impaired quality of life, and early mortality. Studies in Morquio A patients have used the 6-min walk test (6MWT) to assess functionality and endurance and to evaluate disease progression or efficacy of treatment. The objective of the present study was to review minimal clinically important differences (MCIDs) for the 6MWT reported for disease states that widely use the 6MWT to evaluate clinical benefit and to discuss the results in view of the challenges in estimating MCID for ultra-rare diseases, using the case of elosulfase alfa in Morquio A patients...
April 26, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28427318/load-application-for-the-contact-mechanics-analysis-and-wear-prediction-of-total-knee-replacement
#13
Jing Zhang, Zhenxian Chen, Ling Wang, Dichen Li, Zhongmin Jin
Tibiofemoral contact forces in total knee replacement have been measured at the medial and lateral sites respectively using an instrumented prosthesis, and predicted from musculoskeletal multibody dynamics models with a reasonable accuracy. However, it is uncommon that the medial and lateral forces are applied separately to replace a total axial load according to the ISO standard in the majority of current finite element analyses. In this study, we quantified the different effects of applying the medial and lateral loads separately versus the traditional total axial load application on contact mechanics and wear prediction of a patient-specific knee prosthesis...
May 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28422804/a-review-of-ocular-graft-versus-host-disease
#14
Saleha Z Munir, James Aylward
: Graft-versus-host disease (GVHD) is a major complication that occurs following allogeneic hematopoietic stem cell transplantation, which is a potential curative therapy used in a variety of malignant or benign hematological diseases. Graft-versus-host disease primarily occurs in many organs, but most notably in the skin, lungs, gastrointestinal tract, liver, eyes, mucosa, and musculoskeletal system. Ocular manifestations of GVHD may precede other systemic GVHD findings, and it may be a poor prognosis for mortality...
May 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28420054/the-prevalence-and-determinants-of-anti-dfs70-autoantibodies-in-an-international-inception-cohort-of-systemic-lupus-erythematosus-patients
#15
M Y Choi, A E Clarke, Y St Pierre, J G Hanly, M B Urowitz, J Romero-Diaz, C Gordon, S-C Bae, S Bernatsky, D J Wallace, J T Merrill, D A Isenberg, A Rahman, E M Ginzler, M Petri, I N Bruce, M A Dooley, P Fortin, D D Gladman, J Sanchez-Guerrero, K Steinsson, R Ramsey-Goldman, M A Khamashta, C Aranow, G S Alarcón, S Manzi, O Nived, A A Zoma, R F van Vollenhoven, M Ramos-Casals, G Ruiz-Irastorza, S S Lim, K C Kalunian, M Inanc, D L Kamen, C A Peschken, S Jacobsen, A Askanase, J Buyon, M Mahler, M J Fritzler
Autoantibodies to dense fine speckles 70 (DFS70) are purported to rule out the diagnosis of SLE when they occur in the absence of other SLE-related autoantibodies. This study is the first to report the prevalence of anti-DFS70 in an early, multinational inception SLE cohort and examine demographic, clinical, and autoantibody associations. Patients were enrolled in the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort within 15 months of diagnosis. The association between anti-DFS70 and multiple parameters in 1137 patients was assessed using univariate and multivariate logistic regression...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28409175/ct-arthrography-of-adhesive-capsulitis-of-the-shoulder-are-mr-signs-applicable
#16
Cerny Milena, Omoumi Patrick, Larbi Ahmed, Manicourt Daniel, Perozziello Anne, Frederic E Lecouvet, Bruno C Vande Berg, Dallaudière Benjamin
OBJECTIVE: To determine if diagnostic signs of adhesive capsulitis (AC) of the shoulder at Magnetic Resonance Imaging (MRI) and arthrography (MRA) are applicable to CT arthrography (CTA). METHODS: 22 shoulder CTAs with AC were retrospectively reviewed for features described in MR literature. The control group was composed of 83 shoulder CTA divided into four subgroups 1) normal (N = 20), 2) omarthrosis (N = 19), 3) labral injury (N = 23), and 4) rotator cuff tear (N = 21)...
2017: European Journal of Radiology Open
https://www.readbyqxmd.com/read/28401441/effect-of-inpatient-multicomponent-occupational-rehabilitation-versus-less-comprehensive-outpatient-rehabilitation-on-sickness-absence-in-persons-with-musculoskeletal-or-mental-health-disorders-a-randomized-clinical-trial
#17
Lene Aasdahl, Kristine Pape, Ottar Vasseljen, Roar Johnsen, Sigmund Gismervik, Vidar Halsteinli, Nils Fleten, Claus Vinther Nielsen, Marius Steiro Fimland
Purpose To assess effects of an inpatient multicomponent occupational rehabilitation program compared to less comprehensive outpatient rehabilitation on sickness absence in persons with musculoskeletal- or mental health disorders. Methods Randomized clinical trial with parallel groups. Participants were individuals 18-60 years old on sick-leave for 2-12 months with a sick-leave diagnosis within the musculoskeletal, psychological or general and unspecified chapters of ICPC-2, identified in a national register...
April 11, 2017: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/28390140/quantitative-sonographic-assessment-of-the-quadriceps-femoris-muscle-in-healthy-japanese-adults
#18
Tsuneo Watanabe, Hiroki Murakami, Daisuke Fukuoka, Nobuo Terabayashi, Sohee Shin, Tamotsu Yabumoto, Hiroyasu Ito, Hiroshi Fujita, Toshio Matsuoka, Mitsuru Seishima
OBJECTIVES: The aim of this study was to evaluate the relationships among aging, muscle strength, and image feature analysis of the quadriceps femoris muscle and to evaluate the relationship between aging, muscle strength, and sonographic findings. METHODS: One hundred forty-five healthy volunteers participated in the study. The participants were classified into 6 groups on the basis of sex and age. To assess muscle quality, texture analysis was defined with the following parameters: mean, skewness, kurtosis, inverse difference moment, sum of entropy, and angular second moment...
April 8, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28388238/oral-versus-topical-diclofenac-sodium-in-the-treatment-of-osteoarthritis
#19
Vinicius Tieppo Francio, Saeid Davani, Chris Towery, Tony L Brown
Osteoarthritis (OA) is one of the most common causes of joint pain in the United States and non-steroidal anti-inflammatories (NSAIDs), such as Diclofenac sodium, which is currently available in two main routes of administration; oral and topical distribution have been established as one of the standard treatments for OA. Generally, oral NSAIDs are well tolerated; however our narrative review suggests that the topical solution had a better tolerability property than oral Diclofenac sodium, especially due to side effects of gastrointestinal bleeding with the utilization of the oral format...
April 7, 2017: Journal of Pain & Palliative Care Pharmacotherapy
https://www.readbyqxmd.com/read/28379912/functional-and-clinical-outcomes-of-nonsurgically-managed-tibial-plateau-fractures
#20
Christian A Pean, Adam Driesman, Anthony Christiano, Sanjit R Konda, Roy Davidovitch, Kenneth A Egol
INTRODUCTION: This study sought to assess and compare long-term functional and clinical outcomes in patients with tibial plateau fractures that are treated nonsurgically. METHODS: Over a period of 8 years, 305 consecutive tibial plateau fractures were treated by three surgeons at a single institution and followed prospectively in an Institutional Review Board-approved study. Overall, 41 patients (13%) were treated nonsurgically and 37 were available for follow-up...
May 2017: Journal of the American Academy of Orthopaedic Surgeons
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