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Bruno César de Albuquerque Ugoline, Jacqueline de Souza, Fernanda Cristina Ferrari, Zilma Schimith Ferraz Filha, Grazielle Brandão Coelho, Dênia Antunes Saúde-Guimarães
ETHNOPHARMACOLOGICAL RELEVANCE: Lychnophora passerina (Mart ex DC) Gardn (Asteraceae), popularly known as Brazilian arnica, is used in Brazilian folk medicine to treat pain, rheumatism, bruises, inflammatory diseases and insect bites. AIM OF THE STUDY: Investigate the influence of the seasons on the anti-inflammatory and anti-hyperuricemic activities of ethanolic extract of L. passerina and the ratio of the goyazensolide content, main chemical constituent of the ethanolic extract, with these activities...
January 12, 2017: Journal of Ethnopharmacology
Nathaly Alexandre do Nascimento, Lígia Maria Ferreira, Tatiany Patrícia Romão, Darleide Maria da Conceição Correia, Crhisllane Rafaele Dos Santos Vasconcelos, Antônio Mauro Rezende, Samara Graciane Costa, Fernando Ariel Genta, Osvaldo Pompílio de-Melo-Neto, Maria Helena Neves Lobo Silva-Filha
Cqm1 and Aam1 are α-glucosidases (EC expressed in Culex quinquefasciatus and Aedes aegypti larvae midgut, respectively. These orthologs share high sequence similarity but while Cqm1 acts as a receptor for the Binary (Bin) insecticidal toxin from Lysinibacillus sphaericus, Aam1 does not bind the toxin, rendering Ae. aegypti refractory to this bacterium. Aam1 is heavily glycosylated, contrasting to Cqm1, but little is known regarding how glycosylation impacts on its function. This study aimed to compare the N-glycosylation patterns and the catalytic activities of Aam1 and Cqm1...
February 2017: Insect Biochemistry and Molecular Biology
Mariza Miranda Theme Filha, Maria do Carmo Leal, Elaine Fernandes Viellas de Oliveira, Ana Paula Esteves-Pereira, Silvana Granado Nogueira da Gama
BACKGROUND: Mass population screening for the early detection of cervical and breast cancer has been shown to be a safe and effective strategy worldwide and has reduced the incidence and mortality rates of these diseases. The aim of this study is to analyse the reach of screening tests for cervical and breast cancer according to sociodemographic variables and to analyse their correlation with a healthy lifestyle. METHODS: We have analysed data collected from 31...
November 17, 2016: International Journal for Equity in Health
Marcia Leonardi Baldisserotto, Mariza Miranda Theme Filha, Silvana Granado Nogueira da Gama
BACKGROUND: The World Health Organization recommends good practices for the conduct of uncomplicated labor and birth, with the aim of improving the quality of and assessment by women of childbirth care. The aim of this study was to evaluate the association between adoption of good practices according to WHO's recommendation for normal labor and birth and assessment by women of the care received. METHODS: Birth in Brazil is a national hospital-based study with countrywide representation consisting of 23,894 mothers and their newborns, conducted between February 2011 and October 2012...
October 17, 2016: Reproductive Health
Maria do Carmo Leal, Ana Paula Esteves-Pereira, Marcos Nakamura-Pereira, Jacqueline Alves Torres, Mariza Theme-Filha, Rosa Maria Soares Madeira Domingues, Marcos Augusto Bastos Dias, Maria Elizabeth Moreira, Silvana Granado Gama
BACKGROUND: The rate of preterm birth has been increasing worldwide, including in Brazil. This constitutes a significant public health challenge because of the higher levels of morbidity and mortality and long-term health effects associated with preterm birth. This study describes and quantifies factors affecting spontaneous and provider-initiated preterm birth in Brazil. METHODS: Data are from the 2011-2012 "Birth in Brazil" study, which used a national population-based sample of 23,940 women...
October 17, 2016: Reproductive Health
Silvana Granado Nogueira da Gama, Elaine Fernandes Viellas, Jacqueline Alves Torres, Maria Helena Bastos, Odaléa Maria Brüggemann, Mariza Miranda Theme Filha, Arthur Orlando Correa Schilithz, Maria do Carmo Leal
BACKGROUND: The participation of nurses and midwives in vaginal birth care is limited in Brazil, and there are no national data regarding their involvement. The goal was to describe the participation of nurses and nurse-midwives in childbirth care in Brazil in the years 2011 and 2012, and to analyze the association between hospitals with nurses and nurse-midwives in labor and birth care and the use of good practices, and their influence in the reduction of unnecessary interventions, including cesarean sections...
October 17, 2016: Reproductive Health
Mariza Miranda Theme-Filha, Marcia Leonardi Baldisserotto, Ana Claudia Santos Amaral Fraga, Susan Ayers, Silvana Granado Nogueira da Gama, Maria do Carmo Leal
BACKGROUND: Unintended pregnancy, a pregnancy that have been either unwanted or mistimed, is a serious public health issue in Brazil. It is reported for more than half of women who gave birth in the country, but the characteristics of women who conceive unintentionally are rarely documented. The aim of this study is to analyse the prevalence and the association between unintended pregnancy and a set of sociodemographic characteristics, individual-level variables and history of obstetric outcomes...
October 17, 2016: Reproductive Health
Natália Martinez Fernandes, Isadora Gonçalves Pelissari, Licia Assunção Cogo, Valdete Alves Valentins Dos Santos Filha
Introduction The manipulation of antineoplastic drugs presents high risk for accidents and occupational diseases. Objective To evaluate the auditory and vestibular systems of workers who are exposed to chemotherapeutic treatment in the University Hospital of Universidade Federal de Santa Maria, Brazil, and to identify the use of individual protection equipment, related to the obtained results. Methods This study is a cross-sectional study using a quantitative method. We evaluate 33 male and female workers, ranging from 21-60 years old, of the nursing and pharmacy sectors...
October 2016: International Archives of Otorhinolaryngology
Dayane Domeneghini Didoné, Michele Vargas Garcia, Sheila Jacques Oppitz, Thalisson Francisco Finamôr da Silva, Sinéia Neujahr Dos Santos, Rúbia Soares Bruno, Valdete Alves Valentins Dos Santos Filha, Pedro Luis Cóser
OBJECTIVE: To establish reference intervals for cognitive potential P300 latency using tone burst stimuli. METHODS: This study involved 28 participants aged between 18 and 59 years. P300 recordings were performed using a two-channel device (Masbe, Contronic). Electrode placement was as follows: Fpz (ground electrode), Cz (active electrode), M1 and M2 (reference electrodes). Intensity corresponded to 80 dB HL and frequent and rare stimulus frequencies to 1,000Hz and 2,000Hz, respectively...
April 2016: Einstein
Josete Garcia Bersano, Márcia Cristina Mendes, Fernanda Calvo Duarte, Claudia Del Fava, Sueli Moda de Oliveira, Elizabeth Spósito Filha, Eliana Scarcelli Pinheiro, Alessandra Figueiredo de Castro Nassar, Maria Cristina de Vasconcellos Bilynskyj, Renato Akio Ogata, Paulo Henrique Selbmann Sampaio, Margareth Élide Genovez
This paper reports the occurrence of porcine demodicosis caused by the mite Demodex phylloides in hogs reared in a peri-urban family farm located in Francisco Morato, a municipality of the Metropolitan Region of São Paulo, capital city of the state of São Paulo, Brazil. In a parcel of forty Landrace - Large White cross hogs, approximately four months old, four animals presented severe skin lesions in the form of small nodules over their entire body, especially in the periocular region, snout, lower abdomen and flanks...
October 30, 2016: Veterinary Parasitology
Maria do Carmo Leal, Ana Paula Esteves-Pereira, Marcos Nakamura-Pereira, Jacqueline Alves Torres, Rosa Maria Soares Madeira Domingues, Marcos Augusto Bastos Dias, Maria Elizabeth Moreira, Mariza Theme-Filha, Silvana Granado Nogueira da Gama
BACKGROUND: A large proportion of the rise in prematurity worldwide is owing to late preterm births, which may be due to the expansion of obstetric interventions, especially pre-labour caesarean section. Late preterm births pose similar risks to overall prematurity, making this trend a concern. In this study, we describe factors associated with provider-initiated late preterm birth and verify differences in provider-initiated late preterm birth rates between public and private health services according to obstetric risk...
2016: PloS One
Zilma Schimith Ferraz-Filha, Marcela Carolina de Paula Michel Araújo, Fernanda Cristina Ferrari, Iális Paiva Andrade Rodrigues Dutra, Dênia Antunes Saúde-Guimarães
Tabebuia species have several uses in folk medicine, including their use to treat inflammation and rheumatism. The aim of this study was to investigate whether the ethanolic extract of leaves from Tabebuia roseoalba and isolated compounds could be useful to decrease serum uric acid levels and restrain the gout inflammatory process. The compounds α-amyrin, β-amyrin, sitosterol, and stigmasterol were isolated from the ethanolic extract. Rutin and caffeic acid were identified in the ethanolic extract by HPLC analysis...
November 2016: Planta Medica
Mariza Miranda Theme Filha, Paulo Roberto Borges de Souza Junior, Giseli Nogueira Damacena, Celia Landmann Szwarcwald
OBJECTIVE: To analyze the profile of 10 chronic noncommunicable diseases investigated in the National Health Survey carried out in Brazil in 2013 and their association with the self-rated health. METHODS: A cross-sectional, population-based nationwide study with 60,202 individuals aged 18 years old or more. Sampling process by conglomerate was carried out in three stages of selection: census tract, household, and individual. The prevalence of chronic diseases by age, gender and educational status and the confidence intervals of 95% , the mean age at the first diagnosis and the proportion of limitation of the usual activities were calculated...
December 2015: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
Heverly Suzany Gouveia Menezes, Karlos Diogo de Melo Chalegre, Tatiany Patrícia Romão, Cláudia Maria Fontes Oliveira, Osvaldo Pompílio de-Melo-Neto, Maria Helena Neves Lobo Silva-Filha
BACKGROUND: The Cqm1 α-glucosidase of Culex quinquefasciatus larvae acts as the midgut receptor for the binary toxin of the biolarvicide Lysinibacillus sphaericus. Mutations within the cqm1 gene can code for aberrant polypeptides that can no longer be properly expressed or bind to the toxin, leading to insect resistance. The cqm1 REC and cqm1 REC-2 alleles were identified in a laboratory selected colony and both displayed mutations that lead to equivalent phenotypes of refractoriness to L...
February 4, 2016: Parasites & Vectors
Mariza Miranda Theme Filha, Susan Ayers, Silvana Granado Nogueira da Gama, Maria do Carmo Leal
BACKGROUND: Depression is one of the most common postpartum mental disorders. Many sociodemographic and individuals risk factors are associated with maternal depression but the impact of high levels of birth intervention is unclear. The Brazilian context is characterized by excessive intervention and frequent non-compliance with recommended obstetric protocols. This study therefore examined the impact of sociodemographic, individual, and obstetric risk factors in postpartum depression...
April 2016: Journal of Affective Disorders
Tábada Samantha Marques Rosa, Anaelena Bragança de Moraes, Valdete Alves Valentins dos Santos Filha
INTRODUCTION: Dizziness is among the most common complaints in the elderly population. OBJECTIVE: To determine the sociodemographic and clinical-functional profiles of institutionalized elderly people related to dizziness. METHODS: Cross-sectional prospective study with institutionalized elderly people aged 60 or more years. A questionnaire on sociodemographic and clinical-functional characteristics was applied, and an anamnesis of occurrence of dizziness was held, as well as the Dizziness Handicap Inventory questionnaire...
March 2016: Brazilian Journal of Otorhinolaryngology
Fernanda Cristina Ferrari, Rita de Cássia Lemos Lima, Zilma Schimith Ferraz Filha, Camila Helena Barros, Marcela Carolina de Paula Michel Araújo, Dênia Antunes Saúde-Guimarães
ETHNOPHARMACOLOGICAL RELEVANCE: Leaves infusion of Pimenta pseudocaryophyllus (Gomes) Landrum is used in Brazilian folk medicine to treat the predisposition to arthritical and gouty affections of the joints, fever and other diseases. A refreshing drink prepared with the specie is also used due to its diuretic, sedative and aphrodisiac actions. AIM OF THE STUDY: The study was undertaken to investigate the mechanisms of anti-hyperuricemic effect and anti-inflammatory activity of P...
March 2, 2016: Journal of Ethnopharmacology
Lícia Assunção Cogo, Valdete Alves Valentins dos Santos Filha, Adriana de Andrade Batista Murashima, Miguel Angelo Hyppolito, Aron Ferreira da Silveira
INTRODUCTION: The vestibular system is responsible for body balance. There are substances that damage it, causing dizziness; these are termed vestibulotoxic substances. Agrochemicals have been investigated for ototoxicity because of studies that identified dizziness as a recurrent symptom among rural workers' complaints. OBJECTIVE: To histopathologically evaluate the vestibular system in guinea pigs exposed to an organophosphate, and to identify the drug's effects on this system...
January 2016: Brazilian Journal of Otorhinolaryngology
Patrícia Alexandra da Graça Dantas Dos Reis, Claudia Cristina de Aguiar Pereira, Iuri da Costa Leite, Mariza Miranda Theme Filha
We investigated factors associated with adequacy of prenatal and childbirth care for women in São Tomé and Príncipe. Data were analyzed from the Demographic and Health Survey on a sample of 1,326 newborn infants whose mothers were 15-49 years of age. The survey took place from September 2008 to March 2009. We used multilevel and multinomial logistic regression to analyze the association between demographic and socioeconomic factors and the target outcomes. Prenatal care was adequate in 26% of the sample, and 7% of deliveries were performed by physicians and 76% by nurses or nurse assistants...
September 2015: Cadernos de Saúde Pública
A L Zara, C M Martelli, J B Siqueira-Jr, M P Parente, C Braga, C S Oliveira, F G Pimenta-Jr, F Cortes, L R Bahia, M C Mendes, M Quarti, N T Siqueira-Filha, W V Souza, C M Toscano
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
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