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https://www.readbyqxmd.com/read/28923373/outbreak-of-burkholderia-cepacia-bacteraemia-in-a-tertiary-care-centre-due-to-contaminated-ultrasound-probe-gel
#1
Rehab Abdelfattah, Suliman Aljumaah, Ahmed Alqahtani, Sahar Althawadi, Irene Barron, Saleh Almofada
BACKGROUND: Burkholderia cepacia is a significant opportunistic organism in hospitalized and immunocompromised patients, particularly in cystic fibrosis [1] AIMS: We describe the epidemiological investigation of an outbreak of B. cepacia bacteraemia. METHODS: The study examined 14 patients during their admission to three ICUs (Intensive Care Units) in a tertiary care hospital between January-June 2016. The outbreak involved 9 (57%) female and 6 (43%) male patients...
September 15, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28918445/pre-emptive-intestinal-transplant-the-surgeon-s-point-of-view
#2
REVIEW
Augusto Lauro, Ignazio R Marino, Kishore R Iyer
Pre-emptive transplantation is a well-established practice for certain types of end-organ failure such as in the use of kidney transplantation. For irreversible intestinal failure, total parenteral nutrition (TPN) remains the gold standard, due to the suboptimal long-term results of intestinal transplantation. As such, the only role for pre-emptive transplantation, if at all, will be for patients identified to be at high risk of complications and mortality while on definitive long-term TPN. In these patients, the timing of early listing and transplantation could become life-saving, taking into account that mortality on the waiting list is still the highest for intestinal candidates...
September 16, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28916373/methods-for-computational-disease-surveillance-in-infection-prevention-and-control-statistical-process-control-versus-twitter-s-anomaly-and-breakout-detection-algorithms
#3
Timothy L Wiemken, Stephen P Furmanek, William A Mattingly, Marc-Oliver Wright, Annuradha K Persaud, Brian E Guinn, Ruth M Carrico, Forest W Arnold, Julio A Ramirez
BACKGROUND: Although not all health care-associated infections (HAIs) are preventable, reducing HAIs through targeted intervention is key to a successful infection prevention program. To identify areas in need of targeted intervention, robust statistical methods must be used when analyzing surveillance data. The objective of this study was to compare and contrast statistical process control (SPC) charts with Twitter's anomaly and breakout detection algorithms. METHODS: SPC and anomaly/breakout detection (ABD) charts were created for vancomycin-resistant Enterococcus, Acinetobacter baumannii, catheter-associated urinary tract infection, and central line-associated bloodstream infection data...
September 12, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28912948/outbreak-of-fusarium-oxysporum-infections-in-children-with-cancer-an-experience-with-7-episodes-of-catheter-related-fungemia
#4
Fabianne Carlesse, Anna-Paula C Amaral, Sarah S Gonçalves, Hemilio Xafranski, Maria-Lucia M Lee, Victor Zecchin, Antonio S Petrilli, Abdullah M Al-Hatmi, Ferry Hagen, Jacques F Meis, Arnaldo L Colombo
BACKGROUND: Fusarium species are widely spread in nature as plant pathogens but are also able to cause opportunistic fungal infections in humans. We report a cluster of Fusarium oxysporum bloodstream infections in a single pediatric cancer center. METHODS: All clinical and epidemiological data related to an outbreak involving seven cases of fungemia by Fusarium oxysporum during October 2013 and February 2014 were analysed. All cultured isolates (n = 14) were identified to species level by sequencing of the TEF1 and RPB2 genes...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28904476/a-methodological-study-to-develop-a-standard-operational-protocol-for-nurses-on-central-line-catheter-care-of-patients-in-selected-intensive-care-units
#5
Rashmita Devi, Sandhya Ghai, Neena Vir Singh, G D Puri
AIM: This study aims to develop a standard operational protocol (SOP) for central line catheter care for nurses. MATERIALS AND METHODS: A preliminary draft of protocol based on extensive review of the literature was developed. The current practices of the nurses regarding central line catheter care were observed. Focus group discussions (FGD) were conducted with the nurses to identify the problems encountered by them during care of central line. Four rounds of Delphi were conducted to validate the protocol...
August 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28899444/use-of-implementation-science-for-a-sustained-reduction-of-central-line-associated-bloodstream-infections-in-a-high-volume-regional-burn-unit
#6
Geeta Sood, Julie Caffrey, Kelly Krout, Zeina Khouri-Stevens, Kevin Gerold, Stefan Riedel, Janet McIntyre, Lisa L Maragakis, Renee Blanding, Jonathan Zenilman, Richard Bennett, Peter Pronovost
OBJECTIVE We describe the use of implementation science at the unit level and organizational level to guide an intervention to reduce central-line-associated bloodstream infections (CLABSIs) in a high-volume, regional, burn intensive care unit (BICU). DESIGN A single center observational quasi-experimental study. SETTING A regional BICU in Maryland serving 300-400 burn patients annually. INTERVENTIONS In 2011, an organizational-level and unit-level intervention was implemented to reduce the rates of CLABSI in a high-risk patient population in the BICU...
September 13, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28894766/potentially-preventable-hospitalizations-and-the-burden-of-healthcare-associated-infections
#7
Andrea L Lorden, Luohua Jiang, Tiffany A Radcliff, Kathleen A Kelly, Robert L Ohsfeldt
BACKGROUND: An estimated 4% of hospital admissions acquired healthcare-associated infections (HAIs) and accounted for $9.8 (USD) billion in direct cost during 2011. In 2010, nearly 140 000 of the 3.5 million potentially preventable hospitalizations (PPHs) may have acquired an HAI. There is a knowledge gap regarding the co-occurrence of these events. AIMS: To estimate the period occurrences and likelihood of acquiring an HAI for the PPH population. METHODS: Retrospective, cross-sectional study using logistic regression analysis of 2011 Texas Inpatient Discharge Public Use Data File including 2...
January 2017: Health Services Research and Managerial Epidemiology
https://www.readbyqxmd.com/read/28894349/epr-line-shifts-and-line-shape-changes-due-to-spin-exchange-between-nitroxide-free-radicals-in-liquids-10-spin-exchange-frequencies-of-the-order-of-the-nitrogen-hyperfine-interaction-a-hypothesis
#8
Barney L Bales, Miroslav Peric
The behavior of Electron paramagnetic resonance spectra due to (15)N and (14)N nitroxide free radicals undergoing spin exchange in liquids at high frequencies ωex , of the same order of magnitude as the nitrogen hyperfine coupling constant A0 is investigated. The well known features are reconfirmed: (1) at low values of ωex where the lines broaden, shift toward the center of the spectrum, and change shape due to the introduction of a resonance of the form of a dispersion component; (2) at values of ωex comparable to A0, the line merge into one; and (3) at values much larger than A0, the merged line narrows...
February 2017: Applied Magnetic Resonance
https://www.readbyqxmd.com/read/28892887/active-surveillance-of-health-care-associated-infections-in-neurosurgical-patients
#9
Reshu Agarwal, Sarita Mohapatra, Girija Prasad Rath, Arti Kapil
INTRODUCTION: Health Care Associated Infections (HCAI) are frequent complications in neurosurgery. There is limited data available on the incidence and burden of HCAI in neurosurgical patients of Southeast Asian region. AIM: To identify various HCAIs, associated aetiological agents and their antimicrobial susceptibility pattern among the patients admitted in the neurosurgery unit. MATERIALS AND METHODS: An observational prospective study was carried out for three months duration on all neurosurgical patients admitted to a tertiary-care center...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28888825/multimodal-interventions-for-bundle-implementation-to-decrease-central-line-associated-bloodstream-infections-in-adult-intensive-care-units-in-a-teaching-hospital-in-taiwan-2009-2013
#10
Wu-Pu Lin, Yu-Ching Chang, Un-In Wu, Mei-Chuan Hung, Pao-Yu Chuang, Jann-Tay Wang, Wang-Huei Sheng, Yee-Chun Chen, Shan-Chwen Chang
BACKGROUND: Central line (CL)-associated bloodstream infection (CLABSI) poses a major threat to patient safety and is associated with additional cost. This study investigated the sustained effect of multimodal interventions focusing on CL bundle improvement in the adult intensive care units (ICUs) of a teaching hospital in Taiwan. METHODS: A before-after prospective study was conducted in 17 adult ICUs of a medical center in northern Taiwan from January 2009 to December 2013...
August 26, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28877671/surveillance-of-device-associated-infections-and-mortality-in-a-major-intensive-care-unit-in-the-republic-of-cyprus
#11
Stelios Iordanou, Nicos Middleton, Elizabeth Papathanassoglou, Vasilios Raftopoulos
BACKGROUND: Device-associated health care-associated infections (DA-HAI) pose a threat to patient safety, particularly in the intensive care unit. The aim of this study was to assess the incidence of DA-HAIs, mortality and crude excess mortality at a General Hospital's Intensive Care Unit (ICU) in the Republic of Cyprus for 1 year period. METHODS: A prospective cohort, active DA-HAIs surveillance study with the use of Health Acquired Infections (HAIs) ICU Protocol (v1...
September 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28876571/duodenectomy-managing-the-fistula
#12
M Govender, O Matsevych, F Ghoor, N Singh, C Molenaar
BACKGROUND: Duodenectomy is rarely indicated, however, in certain circumstances may have be performed. Enterocutaneous fistula (ECF) is the main cause of serious adverse outcomes. Its management remains challenging. METHOD: Two cases of emergency duodenectomy are presented. The management of ECF is described and discussed. RESULTS: Case 1: A 22-year-old male presented in septic shock with perforated duodenal ulcer, suffered two cardiac arrests before index surgery...
September 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28875883/central-line-associated-bloodstream-infections-in-a-resource-limited-south-african-neonatal-intensive-care-unit
#13
C Geldenhuys, A Dramowski, A Jenkins, A Bekker
BACKGROUND: The rate of central-line-associated bloodstream infection (CLABSI) in South African (SA) public sector neonatal intensive care units (NICUs) is unknown. Tygerberg Children's Hospital (TCH), Cape Town, introduced a neonatal CLABSI surveillance and prevention programme in August 2012. OBJECTIVES: To describe CLABSI events and identify risk factors for development of CLABSI in a resource-limited NICU. METHODS: A retrospective case-control study was conducted using prospectively collected NICU CLABSI events matched to four randomly selected controls, sampled from the NICU registry between 9 August 2012 and 31 July 2014...
August 25, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28874212/mucosal-barrier-injury-central-line-associated-bloodstream-infections-what-is-the-impact-of-standard-prevention-bundles
#14
Ana M Vaughan, Rachael Ross, Margaret M Gilman, Lauren Satchell, Susan Ditaranto, Anne F Reilly, Leslie S Kersun, Amanda Shanahan, Susan E Coffin, Julia Shaklee Sammons
No abstract text is available yet for this article.
September 6, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28868995/central-line-associated-bloodstream-infections-in-australian-icus-evaluating-modifiable-and-non-modifiable-risks-in-victorian-healthcare-facilities
#15
T Spelman, D V Pilcher, A C Cheng, A L Bull, M J Richards, L J Worth
Central line-associated bloodstream infections (CLABSIs) in intensive care units (ICUs) result in poor clinical outcomes and increased costs. Although frequently regarded as preventable, infection risk may be influenced by non-modifiable factors. The objectives of this study were to evaluate organisational factors associated with CLABSI in Victorian ICUs to determine the nature and relative contribution of modifiable and non-modifiable risk factors. Data captured by the Australian and New Zealand Intensive Care Society regarding ICU-admitted patients and resources were linked to CLABSI surveillance data collated by the Victorian Healthcare Associated Infection Surveillance System between 1 January 2010 and 31 December 2013...
September 4, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28868586/the-correlation-between-inferior-vena-cava-diameter-measured-by-ultrasonography-and-central-venous-pressure
#16
Hans Vaish, Virendra Kumar, Rama Anand, Viswas Chhapola, Sandeep Kumar Kanwal
OBJECTIVE: To find a correlation between inferior vena cava (IVC) diameters, IVC compressibility index (CI) and central venous pressure (CVP). METHODS: Prospective observational study was done at pediatric intensive care unit (PICU) of Kalawati Saran Children's Hospital (KSCH). Fifty children aged 5-18 y, presenting with shock were enrolled for the study. IVC diameters, CI and relevant clinical data were noted at enrollment, 30 min, 1 h, 6 h, and 12 h. Central line was placed at the time of admission...
September 4, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28861693/mixed-reality-ultrasound-guidance-system-a-case-study-in-system-development-and-a-cautionary-tale
#17
Golafsoun Ameri, John S H Baxter, Daniel Bainbridge, Terry M Peters, Elvis C S Chen
PURPOSE: Real-time ultrasound has become a crucial aspect of several image-guided interventions. One of the main constraints of such an approach is the difficulty in interpretability of the limited field of view of the image, a problem that has recently been addressed using mixed reality, such as augmented reality and augmented virtuality. The growing popularity and maturity of mixed reality has led to a series of informal guidelines to direct development of new systems and to facilitate regulatory approval...
August 31, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28858967/applying-decision-science-to-the-prioritization-of-healthcare-associated-infection-initiatives
#18
Terry H Tsai, Michael D Gerst, Cyrus Engineer, Harold P Lehmann
OBJECTIVES: Improving patient quality remains a top priority from the perspectives of both patient outcomes and cost of care. The continuing threat to patient safety has resulted in an increasing number of options for patient safety initiatives, making choices more difficult because of competing priorities. This study provides a proof of concept for using low-cost decision science methods for prioritizing initiatives. METHODS: Using multicriteria decision analysis, we developed a decision support model for aiding the prioritization of the four most common types of healthcare-associated infections: surgical site infections, central line-associated bloodstream infections, ventilator-associated events, and catheter-associated urinary tract infections...
August 30, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/28854516/risk-of-morbidity-following-catheter-removal-among-neonates-with-catheter-associated-bloodstream-infection
#19
J S Garland, S Kanneberg, K A Mayr, D M Porter, A Vanden Heuvel, T L McAuliffe
OBJECTIVE: We hypothesized that infectious morbidities following percutaneously inserted central venous catheter (PICC) removal would be greater among neonates with central-line associated bloodstream infection (CLBASI). STUDY DESIGN: This retrospective cohort study, included all neonates who required a PICC over a ten-year period. Outcomes assessed following PICC removal included: late bloodstream infection, rule-out sepsis workups, need for a subsequent PICC and antibiotic days and PICC days after PICC removal...
August 23, 2017: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/28844491/assessing-nurses-adherence-to-a-central-line-maintenance-care-checklist-on-a-pediatric-inpatient-unit
#20
Katherine B Sabo, Emily E Sickbert-Bennett, Ashley A Kellish, Cheryl A Smith-Miller
Adherence to evidence-based central line maintenance practices remains a challenge, particularly in complex patient populations. Using an evidence-based observational checklist, areas of nonadherence were identified and a focused educational intervention was developed, resulting in improved adherence across all aspects of the central line maintenance care bundle.
August 24, 2017: American Journal of Infection Control
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