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https://www.readbyqxmd.com/read/28203417/clinical-factors-associated-with-weaning-failure-in-patients-requiring-prolonged-mechanical-ventilation
#1
Hong-Joon Shin, Jin-Sun Chang, Seong Ahn, Tae-Ok Kim, Cheol-Kyu Park, Jung-Hwan Lim, In-Jae Oh, Yu-Il Kim, Sung-Chul Lim, Young-Chul Kim, Yong-Soo Kwon
BACKGROUND: For patients requiring prolonged mechanical ventilation (PMV), weaning is difficult and mortality is very high. PMV has been defined recently, by consensus, as constituting ≥21 consecutive days of mechanical ventilation (MV) for ≥6 hours per day. This study aimed to evaluate the clinical factors predicting weaning failure in patients undergoing PMV in medical intensive care unit (ICU). METHODS: We retrospectively reviewed the clinical and laboratory characteristics of 127 patients who received MV for more than 21 days in the medical ICU at Chonnam National University Hospital in South Korea between January 2005 and December 2014...
January 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28151912/cystatin-c-is-associated-with-partial-recovery-of-kidney-function-and-progression-to-chronic-kidney-disease-in-living-kidney-donors-observational-study
#2
Ji-Yeon Bang, Seon-Ok Kim, Sae-Gyul Kim, Jun-Gol Song, Gyu Sam Hwang
Donor nephrectomy in living-donor kidney transplantation may result in hyperfiltration injury in remnant kidney; however, its clinical implication in partial recovery of kidney function (PRKF) in remnant kidney and chronic kidney disease (CKD) progression remains unclear. Thus, we investigated the effect of PRKF on CKD development in the residual kidney and the utility of cystatin-C (Cys-C) in evaluating renal function in living-donor kidney transplantation donors.The electronic medical records and laboratory results of 1648 kidney transplant (KT) donors and 13,834 healthy nondonors between January 2006 and November 2014 were reviewed...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28142262/brachial-ankle-pwv-for-predicting-clinical-outcomes-in-patients-with-acute-stroke
#3
Kye Taek Ahn, Jin-Ok Jeong, Seon-Ah Jin, Mijoo Kim, Jin Kyung Oh, Ung-Lim Choi, Seok-Woo Seong, Jun Hyung Kim, Si Wan Choi, Hye Seon Jeong, Hee-Jung Song, Jei Kim, In-Whan Seong
BACKGROUND: Although brachial-ankle pulse wave velocity (baPWV) is well-known for predicting the cardiovascular mortality and morbidity, its anticipated value is not demonstrated well concerning acute stroke. METHODS: Total 1557 patients with acute stroke who performed baPWV were enrolled. We evaluated the prognostic value of baPWV predicting all-cause death and vascular death in patients with acute stroke Results: Highest quartile of baPWV was ≥23.64 m/s. All-caused deaths (including vascular death; 71) were 109 patients during follow-up periods (median 905 days)...
January 31, 2017: Blood Pressure
https://www.readbyqxmd.com/read/28138899/case-control-study-of-postoperative-blood-pressure-in-patients-with-hemorrhagic-complications-after-laparoscopic-sleeve-gastrectomy-and-matched-controls
#4
Michał Robert Janik, Tomasz Rogula, Piotr Kowalewski, Maciej Walędziak, Maciej Matłok, Jakkub Brągoszewski, Andrzej Kwiatkowski, Krzysztof Paśnik
INTRODUCTION: Laparoscopic sleeve gastrectomy is associated with a moderate risk of hemorrhagic complications (HC). There is a debate regarding the relationship between HC and high blood pressure in postoperative period. AIM: The aim is to clarify whether the postoperative blood pressure is an independent risk factor for hemorrhagic complications after laparoscopic sleeve gastrectomy. METHODS: Medical records of 522 patients were reviewed...
January 30, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28125550/o-002-predicting-a-complicated-course-for-children-newly-diagnosed-with-crohn-s-disease-a-multicenter-inception-cohort-study
#5
Subra Kugathasan, Lee Denson, Thomas Walters, Mi-Ok Kim, Urko Marigorta, Melanie Schirmer, Kajari Mondal, Chunyan Liu, Michael Stephens, Robert Baldassano, James Markowitz, Ramnik Xavier, Bruce Aronow, Greg Gibson, Jeffrey Hyams, Marla Dubinsky
BACKGROUND: A subset of patients with Crohn's disease (CD) rapidly progress to a stricturing or internal penetrating phenotype that requires surgery. Despite great strides in therapy, there have not been population-level declines in the rates of these serious complications or need for surgery in CD. Effective risk stratification models to predict progression to such complications in pediatric CD are presently lacking. We aimed to develop and test a prognostic model incorporating clinical and host biology and integrated the comparative effectiveness of anti-TNF in preventing stricturing or perforating complications...
February 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28108838/clinical-impact-of-preoperative-brain-mr-angiography-and-mr-imaging-in-candidates-for-liver-transplantation-a-propensity-score-matching-study-in-a-single-institution
#6
Mi Sun Chung, Ho Sung Kim, Young-Suk Lim, Sang-Beom Jeon, Seon-Ok Kim, Hwa Jung Kim, Shin Hwang, Seung Chai Jung, Choong Gon Choi, Sang Joon Kim
OBJECTIVES: To investigate the prevalence of cerebrovascular stenosis and white matter lesions on preoperative magnetic resonance angiography (MRA) and magnetic resonance imaging (MRI) in liver transplantation candidates. METHODS: This retrospective study included 1,460 consecutive patients with liver cirrhosis (LC) who underwent MRA with/without brain MRI for pretransplantation evaluation. These patients were matched with 5,331 controls using propensity scores, and the prevalences of significant cerebrovascular stenosis and white matter lesions were compared...
January 20, 2017: European Radiology
https://www.readbyqxmd.com/read/28074153/effects-of-metabolic-syndrome-on-aortic-pulse-wave-velocity
#7
Dong-Hyeon Lee, Ho-Joong Youn, Woo-Baek Chung, Yun-Seok Choi, Jong-Min Lee, Chul-Soo Park, Hae-Ok Jung, Hui-Kyung Jeon, Man-Young Lee
BACKGROUND: The purpose of this study was to compare the value and evaluate the validity of non-invasive methods for the detection of vascular stiffness in never-treated individuals with metabolic syndrome (MetS). METHODS: A total of 59 subjects (mean age, 60 ± 12 years; male:female = 35:24) were enrolled in the study and were categorized into the positive MetS (MetS[+]: N = 32) and negative group (MetS[-]: N = 27), according to the parameters set by the National Cholesterol Education Program's Adult Treatment Panel III...
2017: Clinical Hypertension
https://www.readbyqxmd.com/read/28025382/mortality-reduction-by-post-dilution-online-haemodiafiltration-a-cause-specific-analysis
#8
Menso J Nubé, Sanne A E Peters, Peter J Blankestijn, Bernard Canaud, Andrew Davenport, Muriel P C Grooteman, Gulay Asci, Francesco Locatelli, Francisco Maduell, Marion Morena, Ercan Ok, Ferran Torres, Michiel L Bots
BACKGROUND: From an individual participant data (IPD) meta-analysis from four randomized controlled trials comparing haemodialysis (HD) with post-dilution online-haemodiafiltration (ol-HDF), previously it appeared that HDF decreases all-cause mortality by 14% (95% confidence interval 25; 1) and fatal cardiovascular disease (CVD) by 23% (39; 3). Significant differences were not found for fatal infections and sudden death. So far, it is unclear, however, whether the reduced mortality risk of HDF is only due to a decrease in CVD events and if so, which CVD in particular is prevented, if compared with HD...
December 26, 2016: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/27864714/clinical-features-of-postoperative-anastomotic-bleeding-after-gastrectomy-and-efficacy-of-endoscopic-hemostasis-a-case-control-study
#9
Sunpyo Lee, Ji Yong Ahn, Shin Na, Hee Kyong Na, Kee Wook Jung, Do Hoon Kim, Jeong Hoon Lee, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung, Seon-Ok Kim
BACKGROUND: Postoperative anastomotic bleeding (PAB) is relatively rare; however, it can be lethal if not treated immediately. The aim of our study was to investigate the clinical features of PAB and the efficacy of endoscopic hemostasis (EH) for PAB. METHODS: Between January 2004 and May 2013, 16,591 patients underwent gastrectomy for gastric cancer at Asan Medical Center. Among them, 36 patients who experienced PAB within 2 months after the gastrectomy were enrolled as a case group...
November 18, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27847298/nsp4-antibody-levels-in-rotavirus-gastroenteritis-patients-with-seizures
#10
Jung Sook Yeom, Young-Soo Kim, Jin-Su Jun, Hyun Jung Do, Ji Sook Park, Ji-Hyun Seo, Eun Sil Park, Jae-Young Lim, Hyang-Ok Woo, Chan-Hoo Park, Hee-Shang Youn
BACKGROUND: Rotavirus nonstructural protein 4 (NSP4) has been suggested as a pathogen of rotavirus-associated seizures. We investigated pre-existing serum antibodies against NSP4 and VP6 (the most highly immunogenic rotavirus protein) in patients with rotavirus gastroenteritis and its correlation with the occurrence of seizures. METHODS: With an enzyme-linked immunosorbent assay, IgG and IgA titers against NSP4 (genotype [A] and [B]) and VP6 were measured in acute-phase sera of 202 children aged 0...
November 1, 2016: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/27826637/does-final-component-alignment-correlate-with-alignment-of-the-bone-resection-surfaces-in-cemented-total-knee-arthroplasty
#11
Seung-Suk Seo, Chang-Wan Kim, Chang-Rack Lee, Jin-Hyuk Seo, Do-Hun Kim, Ok-Gul Kim, Young-Kyoung Min
PURPOSE: To examine, with a navigation, whether the final component alignments correlate with alignment of the bone resection surfaces in cemented total knee arthroplasty (TKA), and to evaluate the factors affecting alignment deviation. METHODS: A total of 222 patients (276 knees) who underwent navigation-assisted TKA between September 2012 and January 2014 due to osteoarthritis were retrospectively reviewed. The deviation between the alignment of bone resection surfaces and the final alignment of femoral and tibial components was measured...
November 8, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/27826327/prediction-of-unresponsiveness-to-second-intravenous-immunoglobulin-treatment-in-patients-with-kawasaki-disease-refractory-to-initial-treatment
#12
Euri Seo, Jeong Jin Yu, Hyun Ok Jun, Eun Jung Shin, Jae Suk Baek, Young-Hwue Kim, Jae-Kon Ko
PURPOSE: This study investigated predictors of unresponsiveness to second-line intravenous immunoglobulin (IVIG) treatment for Kawasaki disease (KD). METHODS: This was a single-center analysis of the medical records of 588 patients with KD who had been admitted to Asan Medical Center between 2006 and 2014. Related clinical and laboratory data were analyzed by univariate and multivariate logistic regression analyses. RESULTS: Eighty (13.6%) of the 588 patients with KD were unresponsive to the initial IVIG treatment and received a second dose...
October 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/27825793/adherence-to-the-dietary-guidelines-for-americans-is-associated-with-psychological-resilience-in-young-adults-a-cross-sectional-study
#13
Laura J Lutz, Erin Gaffney-Stomberg, Kelly W Williams, Susan M McGraw, Philip J Niro, J Philip Karl, Sonya J Cable, Thomas L Cropper, James P McClung
BACKGROUND: The 2010 Healthy Eating Index (HEI-2010), a measure of diet quality, is used to quantify adherence to the Dietary Guidelines for Americans. Better HEI scores have been associated with positive health outcomes; however, the relationship between diet quality and psychological resilience, a mental health attribute for coping with adversity, has not been assessed. OBJECTIVE: The objective of the present study was to assess the relationship between diet quality and psychological resilience, and the relationship between resilience and demographics, anthropometrics, socioeconomic status, and health behavior...
November 5, 2016: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/27785837/risk-of-advanced-colorectal-neoplasm-in-patients-with-more-than-10-adenomas-on-index-colonoscopy-a-korean-association-for-the-study-of-intestinal-diseases-kasid-study
#14
Soo-Kyung Park, Sung Wook Hwang, Kyeong Ok Kim, Jae Myung Cha, Sun-Jin Boo, Jeong Eun Shin, Young-Eun Joo, Yunho Jung, Jun Lee, Hyo-Joon Yang, Dong Il Park
BACKGROUND AND AIMS: The number of patients with >10 adenomas is relatively small, and few studies have investigated the risk of colorectal neoplasm (CRN) in these patients. Thus, we aimed to investigate the risk of developing CRN in patients with >10 adenomas and to compare their risk with that of patients with 3-10 adenomas. METHODS: A retrospective multicenter cohort study that included 214 patients with >10 adenomas on index colonoscopy performed between January 2009 and December 2011 and underwent follow-up colonoscopy until December 2015 was conducted...
October 27, 2016: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27771225/the-impact-of-recommended-percutaneous-coronary-intervention-care-on-hospital-outcomes-for-interhospital-transferred-stemi-patients
#15
YeongHo Choi, Yu Jin Lee, Sang Do Shin, Kyoung Jun Song, KyungWon Lee, Eui Jung Lee, Yu Jin Kim, Ki Ok Ahn, Ki Jeong Hong, Young Sun Ro
BACKGROUND: Timely transfer and percutaneous coronary intervention (PCI) with or without thrombolysis are recommended by the American Heart Association (AHA) to care for ST-segment elevation myocardial infarction (STEMI) patients who present first to a non-PCI-capable hospital. This study was to evaluate the impact on in-hospital mortality of the compliance with guidelines regarding to the time of PCI for patients with STEMI who were transferred to a capable PCI hospital. METHODS: We used the CArdioVAscular disease Surveillance data from November 2007 to December 2012 for this study...
January 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27733127/usefulness-of-ascitic-fluid-lactoferrin-levels-in-patients-with-liver-cirrhosis
#16
Sang Soo Lee, Hyun Ju Min, Ja Yun Choi, Hyun Chin Cho, Jin Joo Kim, Jae Min Lee, Hong Jun Kim, Chang Yoon Ha, Hyun Jin Kim, Tae Hyo Kim, Jin Hyun Kim, Ok-Jae Lee
BACKGROUND: Although elevated levels of lactoferrin provide a biomarker for inflammatory bowel diseases and colorectal cancer, the clinical significance of these elevated levels in ascitic fluid of patients with ascites caused by liver cirrhosis is limited. The aims of our study were to investigate the usefulness of ascitic fluid lactoferrin levels for the diagnosis of spontaneous bacterial peritonitis (SBP) in patients with cirrhosis and to evaluate the association between lactoferrin levels and the development of hepatocellular carcinoma (HCC)...
October 13, 2016: BMC Gastroenterology
https://www.readbyqxmd.com/read/27714953/usefulness-of-assisted-procedures-for-arteriovenous-fistula-maturation-without-compromising-access-patency
#17
Hoon Suk Park, Youn Hee Lee, Hyung Wook Kim, Jun Hyun Baik, Yong Sung Won, Cheol Whee Park, Young Ok Kim, Chul Woo Yang, Dong Chan Jin
Introduction To increase the rate of arteriovenous fistula (AVF) use, assisted procedures for immature AVF have been strenuously performed. However, this is controversial in that an AVF matured by these assisted procedures may require more frequent intervention to maintain its patency, and have decreased long-term patency. Methods Eighty four AVFs that were matured with assisted maturation procedures and 266 AVFs that matured spontaneously without intervention, created between November 2009 and March 2013 from the hemodialysis (HD) vascular access (VA) cohort, were compared retrospectively and we also investigated the factors that may influence AVF long-term patency...
October 6, 2016: Hemodialysis International
https://www.readbyqxmd.com/read/27686680/effect-of-ventriculo-arterial-coupling-on-transplant-outcomes-in-cirrhotics-analysis-of-pressure-volume-curve-relations
#18
Won-Jung Shin, Jun-Gol Song, In-Gu Jun, Young-Jin Moon, Hye-Mee Kwon, Kyeowoon Jung, Seon-Ok Kim, Gyu-Sam Hwang
BACKGROUND & AIMS: Ventriculo-arterial coupling (VAC) reflects the interaction between ventricular performance and effective arterial load. Current criteria for cirrhotic cardiomyopathy focus only on cardiac function without addressing the effect of hyperdynamic, low-resistance circulation. We investigated alterations in VAC in cirrhotic patients and their associations with post-liver transplant all-cause mortality. METHODS: In this single institution cohort study, cirrhotic patients who underwent liver transplantation (LT) (n=914) were retrospectively compared with healthy matched controls using noninvasively measured end-systolic ventricular elastance (Ees), arterial elastance (Ea), and VAC (Ea/Ees)...
February 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/27661046/comparison-of-the-incidence-of-emergence-agitation-and-emergence-times-between-desflurane-and-sevoflurane-anesthesia-in-children-a-systematic-review-and-meta-analysis
#19
Byung Gun Lim, Il Ok Lee, Hyeongsik Ahn, Dong Kyu Lee, Young Ju Won, Hyun Jung Kim, Heezoo Kim
BACKGROUND: The differences in the incidence and severity of emergence agitation (EA) and emergence times between desflurane and sevoflurane anesthesia have not been as clearly elucidated in children as in adults. METHODS: The design of the study is a systematic review with meta-analysis of randomized controlled trials. The study methodology is based on the Cochrane Review Methods. A comprehensive literature search was conducted to identify clinical trials comparing the incidence or severity of EA and emergence times in children anesthetized with desflurane or sevoflurane...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27637573/overall-and-cause-specific-mortality-in-korean-patients-with-inflammatory-bowel-disease-a-hospital-based-cohort-study
#20
Ho-Su Lee, Jaewon Choe, Seon-Ok Kim, Sun-Ho Lee, Hyo Jeong Lee, Hyungil Seo, Gwang-Un Kim, Myeongsook Seo, Eun Mi Song, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Kyung-Jo Kim, Byong Duk Ye, Jeong-Sik Byeon, Seung-Jae Myung, Yong Sik Yoon, Chang Sik Yu, Jin-Ho Kim, Suk-Kyun Yang
BACKGROUND AND AIM: Limited data are available regarding mortality from inflammatory bowel disease in non-Caucasian populations. Herein, we evaluated overall and cause-specific mortality in a hospital-based cohort of Korean inflammatory bowel disease patients. METHODS: We determined mortality in 2,414 Crohn's disease patients and 2,798 ulcerative colitis patients diagnosed between 1977 and 2013. Standardized mortality ratios were calculated in several demographic and phenotypic subgroups...
September 16, 2016: Journal of Gastroenterology and Hepatology
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