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https://www.readbyqxmd.com/read/29028816/comparison-of-acute-kidney-injury-between-open-and-laparoscopic-liver-resection-propensity-score-analysis
#1
Young-Jin Moon, In-Gu Jun, Ki-Hun Kim, Seon-Ok Kim, Jun-Gol Song, Gyu-Sam Hwang
The inflammatory response has been shown to be a major contributor to acute kidney injury. Considering that laparoscopic surgery is beneficial in reducing the inflammatory response, we compared the incidence of postoperative acute kidney injury between laparoscopic liver resection and open liver resection. Among 1173 patients who underwent liver resection surgery, 222 of 926 patients who underwent open liver resection were matched with 222 of 247 patients who underwent laparoscopic liver resection, by using propensity score analysis...
2017: PloS One
https://www.readbyqxmd.com/read/29026891/effect-of-emergency-medical-service-use-on-time-interval-from-symptom-onset-to-hospital-admission-for-definitive-care-among-patients-with-intracerebral-hemorrhage-a-multicenter-observational-study
#2
Dae Gon Kim, Yu Jin Kim, Sang Do Shin, Kyoung Jun Song, Eui Jung Lee, Yu Jin Lee, Ki Jeong Hong, Ju Ok Park, Young Sun Ro, Yoo Mi Park
OBJECTIVE: This study evaluated whether emergency medical service (EMS) use was associated with early arrival and admission for definitive care among intracerebral hemorrhage (ICH) patients. METHODS: Patients with ICH were enrolled from 29 hospitals between November 2007 and December 2012, excluding those patients with subarachnoid hemorrhage, traumatic ICH, and missing information. The patients were divided into four groups based on visit type to the definitive hospital emergency department (ED): direct visit by EMS (EMS-direct), direct visit without EMS (non-EMS-direct), transferred from a primary hospital by EMS (EMS-transfer), and transferred from a primary hospital without EMS (non-EMS-transfer)...
September 2017: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/28992160/physicians-and-pharmacists-perceptions-on-real-time-drug-utilization-review-system-a-nationwide-survey
#3
Seung-Mi Lee, Soo-Ok Lee, Dong-Sook Kim
Objective: To identify healthcare providers' experience and satisfaction for the drug utilization review (DUR) system, their impact on prescription changes following alerts, and difficulties experienced in the system by surveying primary healthcare centers and pharmacies. Design: A cross-sectional nationwide survey. Setting and participants: Approximately 2000 institutions were selected for the survey by a simple random sampling of nationwide primary healthcare centers and community pharmacy approximately practices, and 358 replied...
October 1, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28963520/interplay-between-3-utr-polymorphisms-in-the-methylenetetrahydrofolate-reductase-mthfr-gene-and-the-risk-of-ischemic-stroke
#4
Jung Oh Kim, Han Sung Park, Chang Soo Ryu, Jung-Won Shin, Jinkwon Kim, Seung Hun Oh, Ok Joon Kim, Nam Keun Kim
Stroke incidence is a multifactorial disease and especially hyperhomocysteinemia is associated with a higher risk of stroke. Previous studies have reported a folate metabolism disorder associated with the MTHFR gene. We investigated four single nucleotide polymorphisms in the MTHFR 3'-UTR [2572 C > A (rs4846049), 4869 C > G (rs1537514), 5488 C > T (rs3737967), and 6685 T > C (rs4846048)] to elucidate associations between ischemic stroke prevalence and prognosis. We examined 511 consecutive patients with ischemic stroke...
September 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28960044/an-outbreak-of-measles-in-a-university-in-korea-2014
#5
Young June Choe, Young Joon Park, Ju Whi Kim, Hye Eun Eom, Ok Park, Myoung Don Oh, Jong Koo Lee
Measles has been declared eliminated from the Korea since 2006. In April 2014, a measles outbreak occurred at a University in Seoul. A total of 85 measles cases were identified. In order to estimate vaccine effectiveness of measles vaccine, we reviewed the vaccination records of the university students. The vaccine effectiveness of two doses of measles containing vaccine was 60.0% (95% CI, 38.2-74.1; P < 0.05). Transmission was interrupted after the introduction of outbreak-response immunization. The outbreak shows that pockets of under-immunity among college students may have facilitated the disease transmission despite the high 2-dose vaccination coverage in the community...
November 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28957722/relationship-between-iron-deficiency-anemia-and-febrile-seizures-in-children-a-systematic-review-and-meta-analysis
#6
Byung Ok Kwak, Kyungmin Kim, Soo-Nyung Kim, Ran Lee
PURPOSE: The association between iron deficiency anemia (IDA) and febrile seizures (FS) during childhood is inconclusive due to inconsistent results reported in different studies. We performed a systematic review and meta-analysis to determine an association between IDA and FS in children. METHODS: We searched PubMed, EMBASE, and Cochrane Library databases for studies published up to August 2015 using the following key words: ["iron deficiency" OR "iron status"] AND ["febrile seizure" OR "febrile convulsion"] AND ["pediatric" OR "infant" OR "child"]...
September 15, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28952823/neurological-favorable-outcomes-associated-with-ems-compliance-and-on-scene-resuscitation-time-protocol
#7
Tae Han Kim, Eui Jung Lee, Sang Do Shin, Young Sun Ro, Yu Jin Kim, Ki Ok Ahn, Kyoung Jun Song, Ki Jeong Hong, Kyung Won Lee
PURPOSE: Korean national emergency care protocol for EMS providers recommends a minimum of 5 minutes of on-scene resuscitation before transport to hospital in cases of Out-of-Hospital Cardiac Arrest (OHCA). We compared survival outcome of OHCA patients according to scene time interval (STI)-protocol compliance of EMS. METHODS: EMS treated adult OHCAs with presumed cardiac etiology during a two-year period were analyzed. Non-compliance was defined as hospital transport with STI less than 6 minutes without return of spontaneous circulation (ROSC) on scene...
September 27, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28951335/the-risk-of-type-2-diabetes-mellitus-according-to-2-hour-plasma-glucose-level-the-korean-genome-and-epidemiology-study-koges
#8
Sung Keun Park, Jae-Hong Ryoo, Chang-Mo Oh, Joong-Myung Choi, Young-Jun Choi, Keum Ok Lee, Ju Young Jung
BACKGROUND: Although impaired glucose tolerance (IGT) is a definite risk factor for type 2 diabetes mellitus (T2DM), there is limited information about the risk stratification for incident T2DM within IGT group. Thus, we aimed to evaluate the incidental risk for T2DM according to 2-hour plasma glucose (2-hr PG) level of oral glucose tolerance test (OGTT) and phenotype of IGT. METHODS: 7,654 Korean participated in the Korean Genome and Epidemiology Study (KoGES) were stratified by 2-hr PG levels of OGTT, and followed up for 63,665 person-years...
August 9, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28934846/egfr-mutation-status-in-lung-adenocarcinoma-associated-malignant-pleural-effusion-and-efficacy-of-egfr-tyrosine-kinase-inhibitors
#9
Jiyoul Yang, Ok-Jun Lee, Seung-Myoung Son, Chang Gok Woo, Yusook Jeong, Yaewon Yang, Jihyun Kwon, Ki Hyeong Lee, Hye Sook Han
Purpose: Malignant pleural effusions (MPEs) are often observed in lung cancer, particularly adenocarcinoma. The aim of this study was to investigate epidermal growth factor receptor (EGFR) mutation status in lung adenocarcinoma-associated MPEs (LA-MPEs) and its correlation with efficacy of EGFR tyrosine kinase inhibitor (TKI) therapy. Methods: Samples comprised 40 cell blocks of pathologically-confirmed LA-MPEs collected before the start of EGFR TKI therapy. EGFR mutation status was re-evaluated by peptide nucleic acid clamping and the clinical outcomes of EGFR TKI-treated patients were analyzed retrospectively...
September 19, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28925344/prehospital-response-time-delays-for-emergency-patients-in-events-of-concurrent-mass-casualty-incidents
#10
Jungeun Kim, Chu Hyun Kim, Sang Do Shin, Ju Ok Park
OBJECTIVE: We investigated the extent of delays in the response time of emergency medical services (EMS) as an impact of mass casualty incidences (MCIs) in the same area. METHODS: We defined an MCI case as an event that resulted in 6 or more patients being transported by EMS, and prehospital response time as the time from the call to arrival at the scene. We matched patients before and after MCIs by dividing them into categories of 3 hours before, 0-1 hour after, 1-2 hours after, and 2-3 hours after the MCIs...
September 19, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28859470/medication-nonadherence-in-korean-patients-with-rheumatoid-arthritis-the-importance-of-belief-about-medication-and-illness-perception
#11
Young Sun Suh, Yun-Hong Cheon, Hyun-Ok Kim, Rock-Bum Kim, Ki Soo Park, Sang-Hyon Kim, Seung-Geun Lee, Eun-Kyoung Park, Jian Hur, Sang-Il Lee
Background/Aims: To investigate medication nonadherence in Korean patients with rheumatoid arthritis (RA) and analyze related factors. Methods: A total of 292 patients with RA participated in this study. Medication nonadherence, intentional or unintentional, was gauged via self-reported questionnaire. Patient perceptions of illness, treatment beliefs, and moods were measured via Brief Illness Perception Questionnaire, Beliefs about Medicines Questionnaire, and Patient Health Questionnaire-2, respectively...
April 20, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28855166/role-of-total-red-processed-and-white-meat-consumption-in-stroke-incidence-and-mortality-a-systematic-review-and-meta-analysis-of-prospective-cohort-studies
#12
REVIEW
Kyuwoong Kim, Junghyeon Hyeon, Sang Ah Lee, Sung Ok Kwon, Hyejin Lee, NaNa Keum, Jong-Koo Lee, Sang Min Park
BACKGROUND: Previous meta-analyses on meat intake and risk of stroke did not report the effect of white meat (poultry meat, excluding fish) and did not examine stroke incidence and mortality separately. We aimed to investigate the relationship of total (red and processed meat), red (unprocessed or fresh red meat), and processed (processed red meat) consumption along with white meat on risk of stroke incidence and mortality. METHODS AND RESULTS: Articles were identified from databases and reference lists of relevant studies up to October 28, 2016...
August 30, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28833495/decreases-in-left-atrial-compliance-during-early-stage-exercise-are-related-to-exercise-intolerance-in-asymptomatic-significant-mitral-stenosis
#13
Mi-Hyang Jung, Hae Ok Jung, Jung-Won Lee, Ho-Joong Youn
BACKGROUND: Doppler-driven net atrioventricular compliance (Cn ), which represents left atrial (LA) compliance, is an important determinant of pulmonary hypertension in mitral stenosis (MS). HYPOTHESIS: We hypothesized that decreases in Cn during early-stage exercise underlie exercise intolerance in patients with MS. METHODS: Thirty-three asymptomatic patients with significant MS (valve area 1.24 ± 0.16 cm(2) ) underwent resting and bicycle exercise echocardiography...
August 22, 2017: Echocardiography
https://www.readbyqxmd.com/read/28827263/effect-of-national-implementation-of-utstein-recommendation-from-the-global-resuscitation-alliance-on-ten-steps-to-improve-outcomes-from-out-of-hospital-cardiac-arrest-a-ten-year-observational-study-in-korea
#14
Young Taek Kim, Sang Do Shin, Sung Ok Hong, Ki Ok Ahn, Young Sun Ro, Kyoung Jun Song, Ki Jeong Hong
OBJECTIVES: The Utstein ten-step implementation strategy (UTIS) proposed by the Global Resuscitation Alliance, a bundle of community cardiopulmonary resuscitation (CPR) programs to improve outcomes after out-of-hospital cardiac arrests (OHCAs), has been developed. However, it is not documented whether UTIS programs are associated with better outcomes or not. The study aimed to test the association between the UTIS programme and better outcomes after OHCA. METHODS: The study was a before- and after-intervention study...
August 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28810723/graft-survival-of-pediatric-kidney-transplant-recipients-selected-for-de-novo-steroid-avoidance-a-propensity-score-matched-study
#15
Edward J Nehus, Chunyan Liu, Bo Lu, Maurizio Macaluso, Mi-Ok Kim
Background: Steroid-avoidance protocols have gained popularity in pediatric kidney transplant recipients at low immunologic risk. The long-term safety of steroid avoidance in children with immunologic risk factors remains unknown. Methods: Pediatric kidney transplant recipients from 2004 to 2014 in the Organ Procurement and Transplantation Network database who received tacrolimus and mycophenolate immunosuppression were investigated. Propensity score matching was used to compare graft survival in 1624 children who received steroid avoidance with 1624 children who received steroid-based immunosuppression...
August 1, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28807551/the-optimal-cut-off-of-blood-pressure-related-to-left-ventricular-diastolic-dysfunction-and-remodeling-in-asian-diabetic-patients
#16
Ju Young Jung, Sung Keun Park, Jae-Hong Ryoo, Chang-Mo Oh, Jeong Gyu Kang, Kanghee Moon, Keum Ok Lee, Joong-Myung Choi
BACKGROUND: Although a recent randomized trial found no difference between intensive and standard blood pressure (BP) control in patients with diabetes mellitus (DM), the debate over the optimal BP target continues. Thus, the present study investigated the effect of BP on the subclinical left ventricular (LV) function and structural changes in diabetic patients. METHOD: A total of 2649 patients with DM who received echocardiography were enrolled in this study. Study population was stratified by three groups according to BP and presence of hypertension (normal, <130/80mmHg; prehypertension, ≥130/80mmHg without hypertension; hypertension, ≥140/90mmHg or history of hypertension)...
August 11, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28797113/clinical-outcomes-of-biodegradable-polymer-biolimus-eluting-biomatrix-stents-versus-durable-polymer-everolimus-eluting-xience-stents
#17
MULTICENTER STUDY
Da Hyon Lee, Taek Kyu Park, Young Bin Song, Woo Jung Chun, Rak Kyeong Choi, Jin-Ok Jeong, Eul Soon Im, Sang Wook Kim, Joo Myung Lee, Jeong Hoon Yang, Joo-Yong Hahn, Seung-Hyuk Choi, Jin-Ho Choi, Sang Hoon Lee, Hyeon-Cheol Gwon
There are limited data about clinical outcomes of biodegradable polymer biolimus-eluting BioMatrix stents (BP-BES) and durable polymer everolimus-eluting Xience stents (DP-EES) in real world practice. We sought to compare the clinical outcomes of BP-BES and DP-EES in real world cohorts of patients undergoing percutaneous coronary intervention. A prospective multicenter registry enrolled 999 patients treated with BP-BES and 1,000 patients treated with DP-EES. The primary outcome was target lesion failure, defined as a composite of cardiac death, target vessel-related myocardial infarction, or target lesion revascularization...
2017: PloS One
https://www.readbyqxmd.com/read/28795051/predictors-of-live-birth-and-pregnancy-success-after-in-vitro-fertilization-in-infertile-women-aged-40-and-over
#18
Hye Ok Kim, Nayoung Sung, In Ok Song
OBJECTIVE: The aim of this study was to evaluate pregnancy outcomes and the live birth rate at 1-year age increments in women aged ≥40 years undergoing fresh non-donor in vitro fertilization (IVF) and embryo transfer (ET), and to identify predictors of success in these patients. METHODS: This retrospective study was performed among women ≥40 years of age between 2004 and 2011. Of the 2,362 cycles that were conducted, ET was performed in 1,532 (73.1%). RESULTS: The clinical pregnancy rate and live birth rate in women ≥40 years significantly decreased with each year of increased age (p<0...
June 2017: Clinical and Experimental Reproductive Medicine
https://www.readbyqxmd.com/read/28793963/the-effect-of-team-based-cardiopulmonary-resuscitation-on-outcomes-in-out-of-hospital-cardiac-arrest-patients-a-meta-analysis
#19
Sola Kim, Ki Ok Ahn, Seungmin Jeong
OBJECTIVES: The objective of this systematic review and meta-analysis was to determine the effects of team cardiopulmonary resuscitation (CPR) on outcomes of patients with out-of-hospital cardiac arrest (OHCA). METHODS: A systematic literature review was performed using PubMed, EMBASE, and the Cochrane database to identify relevant articles for this meta-analysis. All studies that described the implementation of team CPR performed by emergency medical services for OHCA patients with presumed cardiac etiology were included in this study...
July 30, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28780982/validation-of-the-criteria-for-early-critical-care-resource-use-in-assessing-the-effectiveness-of-field-triage
#20
Ki Ok Ahn, Sang Chul Kim, Ju Ok Park, Sang Do Shin, Kyoung Jun Song, Ki Jeong Hong
BACKGROUND: This study aimed to validate the criteria for early critical care resource (CCR) use as an outcome predictor for seriously injured patients triaged in the field by comparing the effectiveness of the criteria for early CCR use with that of criteria defined by an Injury Severity Score (ISS) >15. METHODS: We analysed data from seriously injured trauma patients who were triaged using a field triage protocol by emergency medical service providers (EMS-ST patients)...
July 31, 2017: American Journal of Emergency Medicine
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