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https://www.readbyqxmd.com/read/28822010/vitrification-of-human-immature-oocytes-before-and-after-in-vitro-maturation-a-review
#1
REVIEW
Mohammad Ali Khalili, Abbas Shahedi, Sareh Ashourzadeh, Stefania Annarita Nottola, Guido Macchiarelli, Maria Grazia Palmerini
The use of immature oocytes subjected to in vitro maturation (IVM) opens interesting perspectives for fertility preservation where ovarian reserves are damaged by pathologies or therapies, as in PCO/PCOS and cancer patients. Human oocyte cryopreservation may offer some advantages compared to embryo freezing, such as fertility preservation in women at risk of losing fertility due to oncological treatment or chronic disease, egg donation and postponing childbirth. It also eliminates religious and/or other ethical, legal, and moral concerns of embryo freezing...
August 18, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28820538/from-blue-to-full-color-theoretical-design-and-characterization-of-a-series-of-ir-iii-complexes-containing-azoline-ligand-with-potential-application-in-oleds
#2
Ying-Chen Duan, Yong Wu, Xin-Yao Ren, Liang Zhao, Yun Geng, Min Zhang, Guang-Yan Sun, Zhong-Min Su
Two reported Ir(iii) complexes 1a and 1b containing oxazoline and imidazoline in ancillary ligand, respectively, were investigated by DFT/TD-DFT method. In order to obtain full-color display materials, we designed a group of Ir(iii) complexes 2a-3d based on 1a, which exhibits higher quantum efficiency in phosphorescence, by introducing electron-donating/electron-withdrawing moieties to different positions of the ancillary ligand to adjust emission color. In addition to calculating the radiation rate and analyzing its determining factors, we also estimated nonradiative ability by evaluating the spin-orbit coupling matrix element between the ground state (S0) and the lowest triplet state (T1) as well as the reorganization energy from T1 to S0 to estimate quantum efficiency more accurately...
August 18, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28820534/the-ligand-effect-on-the-oxidative-addition-of-dioxygen-to-gold-i-hydride-complexes
#3
Carlo Alberto Gaggioli, Leonardo Belpassi, Francesco Tarantelli, Jeremy N Harvey, Paola Belanzoni
The ligand effect on the recently uncovered feasible oxidative addition reaction of O2 on [LAuH] complexes has been investigated for a series of fifteen ligands. The activation barriers of this spin-forbidden reaction have been estimated at the minimum energy crossing points (MECP, relativistic scalar level) between the adiabatic triplet (reactants spin state) and singlet (product spin state) potential energy surfaces (PES) and calculated at the transition states by including Spin-Orbit Coupling (SOC) effects, as applied for the mechanistic study of this reaction in a previous study by us [Chem...
August 18, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28819637/cigarette-smoking-and-its-hazards-in-kidney-transplantation
#4
REVIEW
Muhammad Abdul Mabood Khalil, Jackson Tan, Said Khamis, Muhammad AshhadUllah Khalil, Rabeea Azmat, Arslan Rahat Ullah
Cigarette smoking affects many organs. It causes vasoconstriction through activation of sympathetic nervous system which leads to elevation of blood pressure and reduction in glomerular filtration rate and filtration pressure. It also causes thickening of renal arterioles. Cigarette smoking increases the risk of microalbuminuria and accelerates progression of microalbuminuria to macroalbuminuria. Furthermore, it causes rapid loss of glomerular filtration rate in chronic kidney disease patients. After kidney donation, these factors may be injurious to the solitary kidney...
2017: Advances in Medicine
https://www.readbyqxmd.com/read/28819520/the-ban-on-blood-donation-on-men-who-have-sex-with-men-time-to-rethink-and-reassess-an-outdated-policy
#5
Georgios Karamitros, Nikolaos Kitsos, Ioanna Karamitrou
During the 1980s the HIV/AIDS epidemic outbreak occurred. Due to the high prevalence of the disease on men who had sex with men (MSM) a lifetime ban on blood donations on men who had sex with men (MSM) was implemented. In the recent years, organizations like the European Union (EU) and the World Health Organization (WHO) have established new guidelines introducing the term of "risky sexual behavior" without any reference to the sex orientation of the potential donor, however many countries are hesitant to review the ban on men who had sex with men (MSM)...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28819358/surgical-treatment-for-chronic-pancreatitis-past-present-and-future
#6
REVIEW
Stephanie Plagemann, Maria Welte, Jakob R Izbicki, Kai Bachmann
The pancreas was one of the last explored organs in the human body. The first surgical experiences were made before fully understanding the function of the gland. Surgical procedures remained less successful until the discovery of insulin, blood groups, and finally the possibility of blood donation. Throughout the centuries, the surgical approach went from radical resections to minimal resections or only drainage of the gland in comparison to an adequate resection combined with drainage procedures. Today, the well-known and standardized procedures are considered as safe due to the high experience of operating surgeons, the centering of pancreatic surgery in specialized centers, and optimized perioperative treatment...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28818845/a-scoping-review-for-strategies-to-increase-living-kidney-donation
#7
Lianne Barnieh, David Collister, Braden Manns, Ngan N Lam, Soroush Shojai, Diane Lorenzetti, John S Gill, Scott Klarenbach
BACKGROUND AND OBJECTIVES: The literature on strategies to increase the number of potential living kidney donors is extensive and has yet to be characterized. Scoping reviews are a novel methodology for systematically assessing a wide breadth of a given body of literature and may be done before conducting a more targeted systematic review. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We performed a scoping review and summarized the evidence for existing strategies to increase living kidney donation...
August 17, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28818754/daily-thanatomicrobiome-changes-in-soil-as-an-approach-of-postmortem-interval-estimation-an-ecological-perspective
#8
Joe Adserias-Garriga, Marta Hernández, Narciso M Quijada, David Rodríguez Lázaro, Dawnie Steadman, Jesús Garcia-Gil
Understanding human decomposition is critical for its use in postmortem interval (PMI) estimation, having a significant impact on forensic investigations. In recognition of the need to establish the scientific basis for PMI estimation, several studies on decomposition have been carried out in the last years. The aims of the present study were: (i) to identify soil microbiota communities involved in human decomposition through high-throughput sequencing (HTS) of DNA sequences from the different bacteria, (ii) to monitor quantitatively and qualitatively the decay of such signature species, and (iii) to describe succesional changes in bacterial populations from the early putrefaction state until skeletonization...
August 7, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28818537/predicting-grade-and-stage-at-cystoscopy-in-newly-presenting-bladder-cancers-a-prospective-double-blind-clinical-study
#9
Paramananthan Mariappan, Victoria Lavin, Chu Qin Phua, Shahid Aziz Anwar Khan, Roland Donat, Gordon Smith
OBJECTIVES: To assess Urologists' ability to predict the grade and stage of new bladder cancers from the cystoscopic features alone. METHODS: We conducted a prospective clinical study on consecutive patients undergoing Transurethral Resection of Bladder Tumour (TURBT) for new bladder cancers. Using only cystoscopic tumour morphology at the time of initial TURBT, 3 Urology consultants predicted the grade and stage, recording this on a proforma along with tumour features...
August 14, 2017: Urology
https://www.readbyqxmd.com/read/28816459/observation-and-characterization-of-ch3ch2-mh-ch2-2-mh2-ch2-ch-mh3-and-ch3-c%C3%A2-mh3-produced-by-reactions-of-group-5-metal-atoms-with-ethane
#10
Han-Gook Cho, Lester Andrews
The primary products in reactions of laser-ablated group 5 metal atoms with ethane have been identified in argon matrix IR spectra and characterized via DFT computations. The 2nd and 3rd row transition-metals produced insertion, metallacyclopropane, vinyl trihydrido, and anionic ethylidyne complexes (CH3CH2-MH, (CH2)2-MH2, CH2=CH-MH3, and CH3C≡MH3-) while the 1st row transition-metal yielded only the insertion and metallacyclopropane products. The energetically higher ethylidenes and neutral ethylidynes (CH3CH=MH2 and CH3C≐MH3) were not detected...
August 17, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28816393/sperm-donation-perinatal-outcomes-in-an-australian-population-cohort
#11
Damian Adams, Renae Fernandez, Vivienne Moore, Kristyn Willson, Alice Rumbold, Sheryl de Lacey, Wendy Scheil, Michael Davies
AIM: To compare perinatal outcomes for neonates conceived with donated sperm with those for neonates conceived spontaneously in an Australian population cohort. METHODS: Perinatal outcomes for all births in South Australia for the period January 1986-December 2002 were linked with assisted reproductive treatment records to determine those conceived from donated sperm. Birth outcome measures were analyzed using Student's t-test and logistic regression using generalized estimating equations to determine statistical significance...
August 17, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28815613/switching-off-photoprotection-of-photosystem-i-a-novel-tool-for-gradual-psi-photoinhibition
#12
Mikko Tikkanen, Steffen Grebe
Photosystem I (PSI) has evolved in anaerobic atmosphere conditions and until today remains susceptible to oxygen. To minimize the probability of damaging side reactions, plants have evolved sophisticated mechanisms to control electron transfer, and PSI becomes inhibited only when malfunctions of these regulatory mechanisms occur. Due to the complicated induction of PSI photoinhibition, a detailed investigation of the process and following reactions are still largely missing. Here we introduce the theoretical framework and a novel method for an easy and controlled induction of PSI photoinhibition in vivo...
August 16, 2017: Physiologia Plantarum
https://www.readbyqxmd.com/read/28815381/a-virtuous-death-organ-donation-and-eudaimonia
#13
EDITORIAL
David M Shaw
No abstract text is available yet for this article.
August 16, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/28815379/a-450-year-old-turkish-poem-art-as-a-qualitative-investigation-tool-buddhist-deathways-karma-and-eudaimonia-in-death-and-organ-donation-the-wonders-of-truly-diverse-bioethical-inquiry
#14
EDITORIAL
https://www.readbyqxmd.com/read/28815355/egg-donation-of-vitrified-oocytes-bank-produces-similar-pregnancy-rates-by-blastocyst-transfer-when-compared-to-fresh-cycle
#15
Thais S Domingues, Ana Paula Aquino, Bruna Barros, Raquel Mazetto, Mariana Nicolielo, Carolina M Kimati, Talita Devecchi, Tatiana C S Bonetti, Paulo C Serafini, Eduardo L A Motta
PURPOSE: Advances in reproductive techniques, mainly the introduction of oocyte vitrification, have provided the opportunity to conceive from oocyte banks. The aim of this study was to compare the clinical outcomes of fresh and vitrified oocytes in an egg donation program following blastocyst transfer. METHODS: This retrospective observational study included 504 oocyte donation cycles. All donor women were younger than 30 years of age. The recipient cycles were divided into two groups: fresh oocytes (n = 78) or vitrified oocytes (n = 426)...
August 16, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28814758/targeted-insertion-of-an-anti-cd2-monoclonal-antibody-transgene-into-the-ggta1-locus-in-pigs-using-foki-dcas9
#16
Mark B Nottle, Evelyn J Salvaris, Nella Fisicaro, Stephen McIlfatrick, Ivan Vassiliev, Wayne J Hawthorne, Philip J O'Connell, Jamie L Brady, Andrew M Lew, Peter J Cowan
Xenotransplantation from pigs has been advocated as a solution to the perennial shortage of donated human organs and tissues. CRISPR/Cas9 has facilitated the silencing of genes in donor pigs that contribute to xenograft rejection. However, the generation of modified pigs using second-generation nucleases with much lower off-target mutation rates than Cas9, such as FokI-dCas9, has not been reported. Furthermore, there have been no reports on the use of CRISPR to knock protective transgenes into detrimental porcine genes...
August 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28814437/adaptive-responses-of-rat-descending-vasa-recta-to-ischemia
#17
Zhong Zhang, Kristie Payne, Thomas L Pallone
We tested whether rat descending vasa recta (DVR) undergo regulatory adaptions after the kidney is exposed to ischemia. Left kidneys (LK) were subjected to 30 minute renal artery cross clamp. After 48 hours, the post-ischemic LK and contralateral right kidney (RK) were harvested for study. When compared to DVR isolated from either sham operated LK or the contralateral RK, post-ischemic LK DVR markedly increased their NO generation. The selective inducible NOS (iNOS) inhibitor, 1400W, blocked the NO response...
August 16, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28812888/triply-bonded-gallium%C3%A2-phosphorus-molecules-theoretical-designs-and-characterization
#18
Jia-Syun Lu, Ming-Chung Yang, Ming-Der Su
The effect of substitution on the potential energy surfaces of triple-bonded RGa≡PR (R = F, OH, H, CH3, SiH3, SiMe(SitBu3)2, SiiPrDis2, Tbt (C6H2-2,4,6-{CH(SiMe3)2}3), and Ar* (C6H3-2,6-(C6H2-2,4,6-i-Pr3)2)) compounds was theoretically examined by using the density functional theory (i.e., M06-2X/Def2-TZVP, B3PW91/Def2-TZVP and B3LYP/LANL2DZ+dp). The theoretical evidences strongly suggest all of the triple-bonded RGa≡PR species prefer to select a bent form with an angle (∠Ga-P-R) of about 90°. Moreover, the theoretical observations indicate only the bulkier substituents, in particular for the strong donating groups (e...
August 16, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28812887/copper-catalyzed-aerobic-oxidative-regioselective-thiocyanation-of-aromatics-and-heteroaromatics
#19
Huanfeng Jiang, Wentao Yu, Xiaodong Tang, Jianxiao Li, Wanqing Wu
A copper-catalyzed aerobic oxidative reaction between aromatics or heteroaromatics with KSCN is developed by using O2 as the oxidant. The combination of Cu(OTf)2, N,N,N',N'-tetramethylethylene diamine (TMEDA) and BF3•Et2O provides an efficient catalytic system, affording substituted thiocyanation products and 2-amino benzothiazoles in excellent yields. It also possesses a good functional group tolerance for both strong electron-withdrawing and electron-donating groups.
August 16, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28810824/laparoscopic-donor-nephrectomy-early-experience-at-a-single-center-in-pakistan
#20
Rehan Mohsin, Asad Shehzad, Uspal Bajracharya, Bux Ali, Tahir Aziz, Muhammed Mubarak, Altaf Hashmi, Adibul Hasan Rizvi
OBJECTIVES: Laparoscopic donor nephrectomy has become the criterion standard for kidney retrieval from living donors. There is no information on the experience and outcomes of laparoscopic donor nephrectomy in Pakistan. The objective of the study was to identify benefits and harms of using laparoscopic compared with open nephrectomy techniques for renal allograft retrieval. MATERIALS AND METHODS: In this a retrospective study, patient files from May 2014 to September 2015 were analyzed...
August 13, 2017: Experimental and Clinical Transplantation
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