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https://www.readbyqxmd.com/read/28749475/patient-care-standards-for-primary-mitochondrial-disease-a-consensus-statement-from-the-mitochondrial-medicine-society
#1
REVIEW
Sumit Parikh, Amy Goldstein, Amel Karaa, Mary Kay Koenig, Irina Anselm, Catherine Brunel-Guitton, John Christodoulou, Bruce H Cohen, David Dimmock, Gregory M Enns, Marni J Falk, Annette Feigenbaum, Richard E Frye, Jaya Ganesh, David Griesemer, Richard Haas, Rita Horvath, Mark Korson, Michael C Kruer, Michelangelo Mancuso, Shana McCormack, Marie Josee Raboisson, Tyler Reimschisel, Ramona Salvarinova, Russell P Saneto, Fernando Scaglia, John Shoffner, Peter W Stacpoole, Carolyn M Sue, Mark Tarnopolsky, Clara Van Karnebeek, Lynne A Wolfe, Zarazuela Zolkipli Cunningham, Shamima Rahman, Patrick F Chinnery
The purpose of this statement is to provide consensus-based recommendations for optimal management and care for patients with primary mitochondrial disease. This statement is intended for physicians who are engaged in the diagnosis and management of these patients. Working group members were appointed by the Mitochondrial Medicine Society. The panel included members with several different areas of expertise. The panel members utilized surveys and the Delphi method to reach consensus. We anticipate that this statement will need to be updated as the field continues to evolve...
July 27, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/28749016/trends-in-study-design-and-the-statistical-methods-employed-in-a-leading-general-medicine-journal
#2
M Gosho, Y Sato, K Nagashima, S Takahashi
WHAT IS KNOWN AND OBJECTIVE: Study design and statistical methods have become core components of medical research, and the methodology has become more multifaceted and complicated over time. The study of the comprehensive details and current trends of study design and statistical methods is required to support the future implementation of well-planned clinical studies providing information about evidence-based medicine. Our purpose was to illustrate study design and statistical methods employed in recent medical literature...
July 27, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28748890/prevalence-of-hepatitis-b-core-antibodies-with-negative-hepatitis-b-surface-antigen-in-dialysis-and-chronic-kidney-disease-patients
#3
Nauman Tarif, Muhammad Mohsin Riaz, Omer Sabir, Rizwan Akhter, Kashif Rafique, Nabiha Rizvi
Occult hepatitis B infection (OBI) is a potential cause of infection transmission in patients with chronic kidney disease (CKD) and dialysis-dependant patients. It is liable to be missed since the marker for OBI, hepatitis B core antibody (HBcAb), is not done routinely. We carried out a study to assess the prevalence of OBI in CKD Stage II-V or requiring renal replacement therapy. It was a cross-sectional study carried out at Fatima Memorial Hospital, Lahore, from May 2104 to May 2015. A total of 188 patients were included in this study, 124 were dialysis dependent and 64 had acute or CKD Stage II-V...
July 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28748778/wadem-climate-change-position-statement
#4
(no author information available yet)
No abstract text is available yet for this article.
August 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28748774/exposure-to-parental-psychopathology-and-offspring-s-risk-of-suicide-related-thoughts-and-behaviours-a-systematic-review
#5
S M Goodday, J Shuldiner, S Bondy, A E Rhodes
AIMS: The primary objective of this systematic review was to identify and synthesise analytic studies examining the association between exposure to parental psychopathology in childhood and the nature of subsequent suicide-related thoughts (SRT) and suicide-related behaviour (SRB) (severity of ideation, planned/unplanned attempts/lethality) and to describe the direction, and magnitude of associations. The secondary objective was to determine if the associations from the primary objective differ by the type(s) and timing of parental psychopathology, sex/gender of the parent and child and is mediated by child psychiatric symptoms and family functioning...
July 27, 2017: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/28748076/allergens-labeling-on-french-processed-foods-an-oqali-study
#6
Charlène Battisti, Amélie Chambefort, Olivier Digaud, Barbara Duplessis, Cécile Perrin, Jean-Luc Volatier, Julie Gauvreau-Béziat, Céline Menard
The French Observatory of Food Quality (Oqali) aims at collecting all nutritional data provided on labels of processed foods (nutritional information and composition), at branded products level, in order to follow nutritional labeling changes over time. This study carries out an overview of allergens labeling frequencies by distinguishing allergens used in recipes from those listed on precautionary statements, for the fourteen allergen categories for which labeling is mandatory according to European legislation...
July 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28747123/college-releases-new-position-statement-on-mental-health-legislation-and-the-role-of-psychiatrists
#7
(no author information available yet)
No abstract text is available yet for this article.
August 2017: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/28746948/-factors-associated-with-safety-knowledge-on-alpine-ski%C3%A2-slopes
#8
Gerhard Ruedl, Elena Pocecco, Friedrich Brunner, Klaus Greier, Carolin Hildebrandt, Christian Raschner
Background The jurisdiction after a winter sport accident including a third party fault considers the 10 rules for safe skiing/snowboarding introduced by the International Ski Federation (FIS) to clarify the question of liability. A previous study revealed that beginners, young skiers and those who were not local residents displayed insufficient safety knowledge in given situations. The aim of this study was to evaluate additional factors associated with safety knowledge on ski slopes, e. g. type of winter sport, helmet use, risk taking behavior, and a previous injury occurred on a ski slope...
July 26, 2017: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
https://www.readbyqxmd.com/read/28746843/the-role-of-the-microenvironment-in-the-biophysics-of-cancer
#9
REVIEW
Carmela Rianna, Prem Kumar, Manfred Radmacher
During the last decades, cell mechanics has been recognized as a quantitative measure to discriminate between many physiological and pathological states of single cells. In the field of biophysics of cancer, a large body of research has been focused on the comparison between normal and cancer mechanics and slowly the hypothesis that cancer cells are softer than their normal counterparts has been accepted, even though in situ tumor tissue is usually stiffer than the surrounding normal tissue. This corroborates the idea that the extra cellular matrix (ECM) has a critical role in regulating tumor cell properties and behavior...
July 23, 2017: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/28746776/external-cervical-resorption-a-three-dimensional-classification
#10
S Patel, F Foschi, F Mannocci, K Patel
This paper describes a novel 3-dimensional classification for external cervical resorption (ECR). The European Society of Endodontology and American Association of Endodontists & American Academy of Oral & Maxillofacial Radiology position statements advise that CBCT should be considered for the assessment and/or management of root resorption if it appears to be clinically amenable to treatment following clinical and conventional radiographic examination. The new classification takes into account the ECR lesion height (1: At CEJ level or coronal to the bone crest (supracrestal), 2: Extends into the coronal-third of the root and apical to the bone crest (subcrestal), 3: Extends into the mid-third of the root, 4: Extends into the apical-third of the root), circumferential spread (A: ≤ 90° B: ≤180° C: ≤270° D: >270°) and proximity to the root canal (d: Lesion confined to dentine, p: Probable pulpal involvement), thus classifying ECR in 3-dimensions...
July 26, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28745558/ambient-particulate-matter-may-affect-lung-function-of-motorcycle-taxi-drivers-in-bangkok
#11
Sara Arphorn, Tomohiro Ishimaru, Kunio Hara, Suwisa Mahasandana
PURPOSE: The motorcycle taxi drivers of Bangkok have been heavily exposed to high concentrations of PM10 and the impact of this on their lungs has been neither documented nor studied. This study examines the association between exposure to PM10 and lung function decline among motorcycle taxi drivers. METHODS: A cross-sectional study was conducted in Bangkok between two groups: a subject group of motorcycle taxi drivers and control group of enclosed vehicle taxi drivers...
July 26, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/28745155/single-dose-intravenous-paracetamol-or-intravenous-propacetamol-for-postoperative-pain
#12
Amanda Stott
statement The mission of the Cochrane Nursing Care Field (CNCF) is to improve health outcomes through increasing the use of the Cochrane Library and supporting Cochrane's role by providing an evidence base for nurses and healthcare professionals who deliver, lead or research nursing care. The CNCF produces Cochrane Corner columns, summaries of recent nursing-care-relevant Cochrane Reviews that are regularly published in collaborating nursing-related journals. Information on the processes CNCF has developed can be accessed at: cncf...
July 26, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28744695/update-of-the-icud-siu-consultation-on-stone-technology-behind-ureteroscopy
#13
Jonathan Cloutier, Ken Anson, Guido Giusti, Michael Grasso, Guido Kamphuis, Sven Lahme, Evangelos Liatsikos, Anup Patel, Margaret S Pearle, Luc Valiquette, Olivier Traxer
INTRODUCTION: Ureteroscopy is now the most frequent treatment used around the world for stone disease. Technological advancement, efficiency, safety, and minimally invasiveness of this procedure are some of the reasons for this change of trend. MATERIALS AND METHODS: In this review of the literature, a search of the PubMed database was conducted to identify articles related to ureteroscopy and accessories. The committee assigned by the International Consultation on Urological Disease reviewed all the data and produced a consensus statement relating to the ureteroscopy and all the particularities around this procedure...
July 25, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28743827/pnas-plus-significance-statements
#14
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
July 25, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28743665/the-american-academy-of-oral-medicine-clinical-practice-statement-medication-induced-oral-reactions
#15
EDITORIAL
Eric T Stoopler
No abstract text is available yet for this article.
July 22, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28743531/metabolic-regulation-of-glioma-stem-like-cells-in-the-tumor-micro-environment
#16
Tom M Thomas, John S Yu
Cancer metabolism has emerged as one of the most interesting old ideas being revisited from a new perspective. In the early 20(th) century Otto Warburg declared metabolism the prime cause in a disease of many secondary causes, and this statement seems more prescient in view of modern expositions into the true nature of tumor evolution. As the complexity of tumor heterogeneity becomes more clear from a genetic perspective, it is important to consider the inevitably heterogeneous metabolic components of the tumor and the tumor microenvironment...
July 22, 2017: Cancer Letters
https://www.readbyqxmd.com/read/28743242/association-between-the-xrcc1-polymorphisms-and-clinical-outcomes-of-advanced-nsclc-treated-with-platinum-based-chemotherapy-a-meta-analysis-based-on-the-prisma-statement
#17
Dan-Juan Li, Dong Xiao
BACKGROUND: Base excision repair (BER) pathway is a DNA repair pathway that is important in carcinogenesis and in response to DNA-damaging chemotherapy. XRCC1 is one of important molecular markers for BER. So far, the role of XRCC1 polymorphisms with clinical outcomes of advanced NSCLC treated with platinum-based chemotherapy is inconclusive. To explore the relationship between XRCC1 polymorphisms and platinum-based chemotherapy in advanced NSCLC patients, we performed this meta-analysis...
July 25, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28743053/school-staff-members-experience-and-knowledge-in-the-reporting-of-potential-child-and-youth-victimization
#18
Ana M Greco, Georgina Guilera, Noemí Pereda
Victimization has been widely demonstrated to have negative consequences in minors. Most crimes against children go unreported and victims tend to reach adulthood without receiving any of the available specialized support. Studies have highlighted the unique role of school workers in early detection and reporting of possible cases of victimization, and have also found high rates of underreporting by school staff. The present study analyzes the underreporting of child and youth victimization suspicions among school staff and aims to identify variables related to its detection and reporting...
July 22, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28742572/artist-s-statement-in-the-face-of-hunger
#19
Ryan M McAdams
No abstract text is available yet for this article.
August 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28742542/clinical-practice-guidelines-for-cryosurgery-of-pancreatic-cancer-a-consensus-statement-from-the-china-cooperative-group-of-cryosurgery-on-pancreatic-cancer-international-society-of-cryosurgery-and-asian-society-of-cryosurgery
#20
Lihua He, Lizhi Niu, Nikolai N Korpan, Sajio Sumida, Yueyong Xiao, Jiaping Li, Barlian Sutedja, Youyong Lu, Jiansheng Zuo, Jianguo Liu, Kecheng Xu
Pancreatic cancer (PC), one of the most lethal malignancies, accounts for 8% to 10% of digestive system cancers, and the incidence is increasing. Surgery, chemotherapy, and radiotherapy have been the main treatment methods but are not very effective. Cryosurgery was first used in 1984 for treatment of locally advanced PC and has since become a considerable treatment for most cases of unresectable PC. During the past decade, cryosurgery has been applied in some hospitals in China, and the newly developed technique of computed tomography- and/or ultrasound-guided percutaneous cryosurgery has shown better results than chemotherapy in cases of unresectable locally advanced PC, with the 1-year survival rate reported to be more than 50%...
July 24, 2017: Pancreas
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