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https://www.readbyqxmd.com/read/29771383/relationship-of-fibroblast-growth-factor-21-with-kidney-function-and-albuminuria-multi-ethnic-study-of-atherosclerosis
#1
Sahapab Anuwatmatee, Matthew A Allison, Michael G Shlipak, Robyn L McClelland, Holly Kramer, Shudi Tang, Liming Hou, Kerry-Anne Rye, Kwok Leung Ong
Background: Fibroblast growth factor 21 (FGF21) may play a role in the development of chronic kidney disease (CKD). We therefore investigated the relationship of plasma FGF21 levels with kidney function and albuminuria in the Multi-Ethnic Study of Atherosclerosis (MESA). Methods: The analysis included 5724 MESA participants ages 45-84 years between 2000 and 2002, free of clinically apparent cardiovascular disease (CVD). Participants were followed up in person at four additional clinic visits over 10 years...
May 15, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29764436/prevalence-and-incidence-of-complications-at-diagnosis-of-t2dm-and-during-follow-up-by-bmi-and-ethnicity-a-matched-case-control-analysis
#2
Ebenezer S Owusu Adjah, Srikanth Bellary, Wasim Hanif, Kiran Patel, Kamlesh Khunti, Sanjoy K Paul
AIMS: To estimate the risk of developing long-term major cardiovascular and renal complications in relation to levels of body mass index (BMI) in a population of White European (WE), African-Caribbean (AC), and South Asian (SA) patients with type 2 diabetes mellitus (T2DM). MATERIALS AND METHODS: Patients with new diagnosis of T2DM, aged ≥ 18 years from January 2000 (n = 69,436) and their age-sex-ethnicity matched non-diabetic controls (n = 272,190) were identified from UK primary care database...
May 15, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29751988/chronic-kidney-disease-in-persons-living-with-hiv-a-systematic-review
#3
Jungmin Park, Julie Ann Zuñiga
The purpose of our systematic review of research on chronic kidney disease (CKD) in persons living with HIV (PLWH) was to (a) compare and contrast diagnostic criteria for CKD, (b) identify risk factors of CKD in PLWH, and (c) elucidate the prevalence of CKD in PLWH. Keyword searches of PubMed and PsycInfo databases were followed by manual searches of references from 2000 through 2016; 21 studies met inclusion criteria. Sample sizes ranged from 8 to 15,140, with a mean age of 50 years, and represented diverse ethnicities/races and countries of origin...
April 19, 2018: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/29740923/long-term-renal-outcomes-in-multi-ethnic-southeast-asians-with-lupus-nephritis-a-retrospective-cohort-study
#4
Cynthia C Lim, Hui Zhuan Tan, Ying Hao, Yok Mooi Chin, Keng Thye Woo, Choong Meng Chan, Jason Cj Choo
BACKGROUND: Renal involvement is common among Asians with systemic lupus erythematosus and long-term renal outcomes have been described in homogeneous Caucasian and East Asian populations with lupus nephritis but data is scarce for other ethnicities. We aimed to evaluate the incidence and risk factors for progressive chronic kidney disease (CKD) in multi-ethnic South-east Asians with lupus nephritis. METHODS: Single-center retrospective cohort study of adults with biopsy-proven lupus nephritis diagnosed between May 2001 and May 2009...
May 9, 2018: Internal Medicine Journal
https://www.readbyqxmd.com/read/29728316/cognitive-impairment-in-non-dialysis-dependent-ckd-and-the-transition-to-dialysis-findings-from-the-chronic-renal-insufficiency-cohort-cric-study
#5
Meera N Harhay, Dawei Xie, Xiaoming Zhang, Chi-Yuan Hsu, Eric Vittinghoff, Alan S Go, Stephen M Sozio, Jacob Blumenthal, Stephen Seliger, Jing Chen, Rajat Deo, Mirela Dobre, Sanjeev Akkina, Peter P Reese, James P Lash, Kristine Yaffe, Manjula Kurella Tamura
BACKGROUND: Advanced chronic kidney disease is associated with elevated risk for cognitive impairment. However, it is not known whether and how cognitive impairment is associated with planning and preparation for end-stage renal disease. STUDY DESIGN: Retrospective observational study. SETTING & PARTICIPANTS: 630 adults participating in the CRIC (Chronic Renal Insufficiency Cohort) Study who had cognitive assessments in late-stage CKD, defined as estimated glome-rular filtration rate ≤ 20mL/min/1...
May 2, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29717528/the-prevalence-and-risk-factors-for-chronic-kidney-disease-in-primary-health-care-in-the-southern-region-of-new-zealand
#6
Hywel Lloyd, Grace Li, Andrew Tomlin, Murray W Tilyard, Robert Walker, John Schollum
BACKGROUND: While the prevalence of end stage kidney disease in New Zealand (NZ) is well defined, the prevalence of CKD in NZ is unknown. AIM: To estimate the prevalence of and risk factors for CKD in the southern region of New Zealand METHODS: A retrospective electronic health record cohort study using data from the Southern Primary Care register covering 94% of the population. Patients, 20 years or older were identified and linked to laboratory results for serum creatinine and urinary albumin excretion...
May 2, 2018: Nephrology
https://www.readbyqxmd.com/read/29665793/assessing-known-chronic-kidney-disease-associated-genetic-variants-in-saudi-arabian-populations
#7
Cyril Cyrus, Samir Al-Mueilo, Chittibabu Vatte, Shahanas Chathoth, Yun R Li, Hatem Qutub, Rudaynah Al Ali, Fahad Al-Muhanna, Matthew B Lanktree, Khaled Riyad Alkharsah, Abdullah Al-Rubaish, Brian Kim-Mozeleski, Brendan Keating, Amein Al Ali
BACKGROUND: Genome wide association studies of patients with European descent have identified common variants associated with risk of reduced estimated glomerular filtration rate (eGFR). A panel of eight variants were selected to evaluate their association and prevalence in a Saudi Arabian patient cohort with chronic kidney disease (CKD). METHODS: Eight genetic variants in four genes (SHROOM3, MYH9, SLC7A9, and CST3) were genotyped in 160 CKD patients and 189 ethnicity-matched healthy controls...
April 17, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29661541/ckd-and-esrd-in-us-hispanics
#8
REVIEW
Nisa Desai, Claudia M Lora, James P Lash, Ana C Ricardo
Hispanics are the largest racial/ethnic minority group in the United States, and they experience a substantial burden of kidney disease. Although the prevalence of chronic kidney disease (CKD) is similar or slightly lower in Hispanics than non-Hispanic whites, the age- and sex-adjusted prevalence rate of end-stage renal disease is almost 50% higher in Hispanics compared with non-Hispanic whites. This has been attributed in part to faster CKD progression among Hispanics. Furthermore, Hispanic ethnicity has been associated with a greater prevalence of cardiovascular disease risk factors, including obesity and diabetes, as well as CKD-related complications...
April 13, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29593020/ethnic-differences-in-the-progression-of-chronic-kidney-disease-and-risk-of-death-in-a-uk-diabetic-population-an-observational-cohort-study
#9
Rohini Mathur, Gavin Dreyer, Magdi M Yaqoob, Sally A Hull
OBJECTIVE: To determine ethnic differences in the progression of chronic kidney disease (CKD) and risk of end-stage renal failure (ESRF) and death in adults with type 2 diabetes mellitus (T2DM), and to identify predictors of rapid renal decline. DESIGN: Observational community-based cohort study undertaken from 2006 to 2016 with nested case-control study. SETTING: 135 inner London primary care practices contributing to the east London Database...
March 27, 2018: BMJ Open
https://www.readbyqxmd.com/read/29525790/race-ethnicity-dietary-acid-load-and-risk-of-end-stage-renal-disease-among-us-adults-with-chronic-kidney-disease
#10
Deidra C Crews, Tanushree Banerjee, Donald E Wesson, Hal Morgenstern, Rajiv Saran, Nilka Ríos Burrows, Desmond E Williams, Neil R Powe
BACKGROUND: Dietary acid load (DAL) contributes to the risk of CKD and CKD progression. We sought to determine the relation of DAL to racial/ethnic differences in the risk of end-stage renal disease (ESRD) among persons with CKD. METHODS: Among 1,123 non-Hispanic black (NHB) and non-Hispanic white (NHW) National Health and Nutrition Examination Survey III participants with estimated glomerular filtration rate 15-59 mL/min/1.73 m2, DAL was estimated using the Remer and Manz net acid excretion (NAEes) formula and 24-h dietary recall...
2018: American Journal of Nephrology
https://www.readbyqxmd.com/read/29499886/glomerular-filtration-rates-in-asians
#11
REVIEW
Boon Wee Teo, Luxia Zhang, Jinn-Yuh Guh, Sydney C W Tang, Vivekanand Jha, Duk-Hee Kang, Roberto Tanchanco, Lai Seong Hooi, Kearkiat Praditpornsilpa, Xianglei Kong, Li Zuo, Gek Cher Chan, Evan J C Lee
The National Kidney Foundation Kidney Disease Outcomes Quality Initiative guidelines recommended the Modification of Diet in Renal Disease study equation for estimating glomerular filtration rate (GFR) for the classification of CKD, but its accuracy was limited to North American patients with estimated GFR <60 mL/min per 1.73 m2 body surface area of European (White) or African (Black) descent. The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) developed another equation for estimating GFR, derived from a population that included both participants without kidney disease and with CKD...
January 2018: Advances in Chronic Kidney Disease
https://www.readbyqxmd.com/read/29499039/performance-of-glomerular-filtration-rate-estimation-equations-in-congolese-healthy-adults-the-inopportunity-of-the-ethnic-correction
#12
Justine B Bukabau, Ernest K Sumaili, Etienne Cavalier, Hans Pottel, Bejos Kifakiou, Aliocha Nkodila, Jean Robert R Makulo, Vieux M Mokoli, Chantal V Zinga, Augustin L Longo, Yannick M Engole, Yannick M Nlandu, François B Lepira, Nazaire M Nseka, Jean Marie Krzesinski, Pierre Delanaye
CONTEXT AND OBJECTIVE: In the estimation of glomerular filtration rate (GFR), ethnicity is an important determinant. However, all existing equations have been built solely from Caucasian and Afro-American populations and they are potentially inaccurate for estimating GFR in African populations. We therefore evaluated the performance of different estimated GFR (eGFR) equations in predicting measured GFR (mGFR). METHODS: In a cross-sectional study, 93 healthy adults were randomly selected in the general population of Kinshasa, Democratic Republic of the Congo, between June 2015 and April 2016...
2018: PloS One
https://www.readbyqxmd.com/read/29486722/study-protocol-rationale-and-design-of-the-community-based-prospective-cohort-study-of-kidney-function-and-diabetes-in-rural-new-mexico-the-compass-study
#13
Antonin Jaros, Hafiz A Sroya, Venita K Wolfe, Vikas Ghai, Maria-Eleni Roumelioti, Kamran Shaffi, Kai Wang, Vernon Shane Pankratz, Mark L Unruh, Christos Argyropoulos
BACKGROUND: Rural areas in the state of New Mexico have been the "ground-zero" for the epidemic of diabetic Chronic Kidney Disease (CKD) in the United States. However, there is limited research about risk factors of diabetic CKD in this area and scarce data regarding the performance of emerging markers of renal filtration and epigenetic biomarkers of renal function and diabetes in this area with its unique ethnic/racial population. We designed the COMPASS study as a community-based program in rural New Mexico aiming to screen for CKD and to discover CKD-related translational biomarkers...
February 27, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29415666/influence-of-vitamin-d-receptor-polymorphisms-on-biochemical-markers-of-mineral-bone-disorders-in-south-african-patients-with-chronic-kidney-disease
#14
Bala Waziri, Therese Dix-Peek, Caroline Dickens, Raquel Duarte, Saraladevi Naicker
BACKGROUND: It remains unclear whether genetic factors may explain the reported variation in the levels of biochemical markers of chronic kidney disease mineral and bone disorders (CKD- MBD) across ethnic groups. Therefore, the aim of this study was to examine the influence of vitamin D receptor (VDR) polymorphisms on secondary hyperparathyroidism and its association with vitamin D levels in black and white South African study participants. METHODS: This was a cross sectional study involving 272 CKD stage 3- 5D patients and 90 healthy controls...
February 7, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29390980/existing-creatinine-based-equations-overestimate-glomerular-filtration-rate-in-indians
#15
Vivek Kumar, Ashok Kumar Yadav, Yoshinari Yasuda, Masaru Horio, Vinod Kumar, Nancy Sahni, Krishan L Gupta, Seiichi Matsuo, Harbir Singh Kohli, Vivekanand Jha
BACKGROUND: Accurate estimation of glomerular filtration rate (GFR) is important for diagnosis and risk stratification in chronic kidney disease and for selection of living donors. Ethnic differences have required correction factors in the originally developed creatinine-based GFR estimation equations for populations around the world. Existing equations have not been validated in the vegetarian Indian population. We examined the performance of creatinine and cystatin-based GFR estimating equations in Indians...
February 1, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29383256/assessment-of-chronic-kidney-disease-using-skin-texture-as-a-key-parameter-for-south-indian-population
#16
Madhanlal Udhayarasu, Kalpana Ramakrishnan, Soundararajan Periasamy
Periodical monitoring of renal function, specifically for subjects with history of diabetic or hypertension would prevent them from entering into chronic kidney disease (CKD) condition. The recent increase in numbers may be due to food habits or lack of physical exercise, necessitates a rapid kidney function monitoring system. Presently, it is determined by evaluating glomerular filtration rate (GFR) that is mainly dependent on serum creatinine value and demographic parameters and ethnic value. Attempted here is to develop ethnic parameter based on skin texture for every individual...
December 2017: Healthcare Technology Letters
https://www.readbyqxmd.com/read/29375010/aggressive-systolic-blood-pressure-control-in-older-subjects-benefits-and-risks
#17
REVIEW
Steven G Chrysant
Systolic hypertension, especially isolated systolic hypertension (ISH) is very common in older subjects aged ≥ 65 years and is a major risk factor for cardiovascular disease (CVD), strokes, heart failure (HF) and chronic kidney disease (CKD). It is also, directly and linearly related with these complications irrespective of sex, or ethnicity, but it is worse with the advancement of age. Effective control of systolic blood pressure (SBP), is associated with significant reduction in the incidence of these complications...
March 2018: Postgraduate Medicine
https://www.readbyqxmd.com/read/29372064/canadians-seeking-solutions-and-innovations-to-overcome-chronic-kidney-disease-can-solve-ckd-form-and-function
#18
Adeera Levin, Evan Adams, Brendan J Barrett, Heather Beanlands, Kevin D Burns, Helen Hoi-Lun Chiu, Kate Chong, Allison Dart, Jack Ferera, Nicolas Fernandez, Elisabeth Fowler, Amit X Garg, Richard Gilbert, Heather Harris, Rebecca Harvey, Brenda Hemmelgarn, Matthew James, Jeffrey Johnson, Joanne Kappel, Paul Komenda, Michael McCormick, Christopher McIntyre, Farid Mahmud, York Pei, Graham Pollock, Heather Reich, Norman D Rosenblum, James Scholey, Etienne Sochett, Mila Tang, Navdeep Tangri, Marcello Tonelli, Catherine Turner, Michael Walsh, Cathy Woods, Braden Manns
Purpose of review: This article serves to describe the Can-SOLVE CKD network, a program of research projects and infrastructure that has excited patients and given them hope that we can truly transform the care they receive. Issue: Chronic kidney disease (CKD) is a complex disorder that affects more than 4 million Canadians and costs the Canadian health care system more than $40 billion per year. The evidence base for guiding care in CKD is small, and even in areas where evidence exists, uptake of evidence into clinical practice has been slow...
2018: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/29359019/impact-of-sustained-virologic-response-on-chronic-kidney-disease-progression-in-hepatitis-c
#19
Elizabeth S Aby, Tien S Dong, Jenna Kawamoto, Joseph R Pisegna, Jihane N Benhammou
AIM: To determine how sustained virological response at 12 wk (SVR12) with direct acting antivirals (DAAs) for the treatment of hepatitis C virus (HCV) infection affects chronic kidney disease (CKD) progression. METHODS: A retrospective analysis was performed in patients aged ≥ 18 years treated for HCV with DAAs at the VA Greater Los Angeles Healthcare System from 2014-2016. The treatment group was compared to patients with HCV from 2011-2013 who did not undergo HCV treatment, prior to the introduction of DAAs; the control group was matched to the study group in terms of age, gender, and ethnicity...
December 28, 2017: World Journal of Hepatology
https://www.readbyqxmd.com/read/29237422/mdrd-vs-ckd-epi-in-comparison-to-51-chromium-edta-a-cross-sectional-study-of-malaysian-ckd-cohort
#20
Maisarah Jalalonmuhali, Soo Kun Lim, Mohammad Nazri Md Shah, Kok Peng Ng
BACKGROUND: Accurate measurement of renal function is important: however, radiolabelled gold standard measurement of GFR is highly expensive and can only be used on a very limited scale. We aim to compare the performance of Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) equations in the multi-ethnic population attending University Malaya Medical Centre (UMMC). METHODS: This is a cross-sectional study recruiting patients, who attend UMMC Nephrology clinics on voluntary basis...
December 13, 2017: BMC Nephrology
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