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https://www.readbyqxmd.com/read/29144185/rest-activity-circadian-rhythm-and-sleep-quality-in-patients-with-binge-eating-disorder
#1
E Roveda, A Montaruli, L Galasso, C Pesenti, E Bruno, P Pasanisi, M Cortellini, S Rampichini, S Erzegovesi, A Caumo, F Esposito
Recent findings suggest that altered rest-activity circadian rhythms (RARs) are associated with a compromised health status. RARs abnormalities have been observed also in several pathological conditions, such as cardiovascular, neurological, and cancer diseases. Binge eating disorder (BED) is the most common eating disorder, with a prevalence of 3.5% in women and 2% in men. BED and its associate obesity and motor inactivity could induce RARs disruption and have negative consequences on health-related quality of life...
November 16, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29144172/disruptions-in-sleep-wake-cycles-in-community-dwelling-cancer-patients-receiving-palliative-care-and-their-correlates
#2
Marie Solange Bernatchez, Josée Savard, Hans Ivers
Significant disruptions in sleep-wake cycles have been found in advanced cancer patients in prior research. However, much remains to be known about specific sleep-wake cycle variables that are impaired in patients with a significantly altered performance status. More studies are also needed to explore the extent to which disrupted sleep-wake cycles are related to physical and psychological symptoms, time to death, maladaptive sleep behaviors, quality of life and 24-h light exposure. This study conducted in palliative cancer patients was aimed at characterizing patients' sleep-wake cycles using various circadian parameters (i...
November 16, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29144169/bright-light-exposure-during-daytime-sleeping-affects-nocturnal-melatonin-secretion-after-simulated-night-work
#3
Shunsuke Nagashima, Madoka Osawa, Hiroto Matsuyama, Wataru Ohoka, Aemi Ahn, Tomoko Wakamura
The guidelines for night and shift workers recommend that after night work, they should sleep in a dark environment during the daytime. However, staying in a dark environment during the daytime reduces nocturnal melatonin secretion and delays its onset. Daytime bright-light exposure after night work is important for melatonin synthesis the subsequent night and for maintaining the circadian rhythms. However, it is not clear whether daytime sleeping after night work should be in a dim- or a bright-light environment for maintaining melatonin secretion...
November 16, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29144168/the-effects-of-extended-nap-periods-on-cognitive-physiological-and-subjective-responses-under-simulated-night-shift-conditions
#4
Jonathan Davy, Matthias Göbel
Extended nap opportunities have been effective in maintaining alertness in the context of extended night shifts (+12 h). However, there is limited evidence of their efficacy during 8-h shifts. Thus, this study explored the effects of extended naps on cognitive, physiological and perceptual responses during four simulated, 8-h night shifts. In a laboratory setting, 32 participants were allocated to one of three conditions. All participants completed four consecutive, 8-h night shifts, with the arrangements differing by condition...
November 16, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29141950/maternal-circadian-rhythms-and-the-programming-of-adult-health-and-disease
#5
Tamara Jayne Varcoe, Kathryn L Gatford, David J Kennaway
The in utero environment is inherently rhythmic, with the fetus subjected to circadian changes in temperature, substrates and various maternal hormones. Meanwhile, the fetus is developing an endogenous circadian timing system, preparing for life in an external environment where light, food availability and other environmental factors change predictably and repeatedly every 24 hours. In humans, there are many situations that can disrupt circadian rhythms, including shift work, international travel, insomnias and circadian rhythm disorders (e...
November 15, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/29132973/mutual-influence-of-sleep-and-circadian-clocks-on-physiology-and-cognition
#6
REVIEW
Isabel Heyde, Jana-Thabea Kiehn, Henrik Oster
The 24-hour sleep-wake cycle is one of the most prominent outputs of the circadian clock system. At the same time, changes in sleep-wake behavior feedback on behavioral and physiological circadian rhythms, thus altering the coordination of the body's clock network. Sleep and circadian rhythm disruption have similar physiological endpoints including metabolic, cognitive, and immunologic impairments. This raises the question to which extent these phenomena are causally linked. In this review, we summarize different physiologic outcomes of sleep deprivation and mistimed sleep and discuss the experimental evidence for a mediating role of the circadian clock machinery in this context...
November 10, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/29129751/hypoglossal-motoneurons-are-endogenously-activated-by-serotonin-during-the-active-period-of-circadian-cycle
#7
Leszek Kubin, Graziella L Mann
In obstructive sleep apnea patients, contraction of lingual muscles protects the pharyngeal airway from collapse. Hypoglossal (XII) motoneurons innervate the muscles of the tongue and are themselves under wake-related excitatory drives, including that mediated by serotonin (5-HT). Estimates of endogenous 5-HT activation vary among different studies. We tested whether endogenous drive mediated by 5-HT is present in rat XII motoneurons when measured during the active period of the circadian cycle. We monitored sleep-wake states and lingual and nuchal electromyograms (EMGs) while perfusing the XII nucleus with a vehicle or a 5-HT2 receptor antagonist (mianserin, 0...
November 9, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/29129126/chronic-circadian-misalignment-without-circadian-arrhythmicity-or-sleep-deprivation-does-not-impair-adult-hippocampal-neurogenesis
#8
Phan Q Duy, Samer Hattar
Artificial light in modern society has led to the ubiquity of light exposure at night as individuals work night shifts and use light-emitting electronic devices before bedtime. These aberrant light conditions have detrimental consequences on cognitive and mental health, compelling the need to understand the mechanisms by which light affects brain functions. Although it was believed that aberrant light impairs health by first disrupting circadian rhythms and sleep, we showed that chronic exposure to a light cycle termed T7 (3...
November 1, 2017: Journal of Biological Rhythms
https://www.readbyqxmd.com/read/29126328/repeated-administration-effects-on-psychomotor-vigilance-test-pvt-performance
#9
Mathias Basner, Emanuel Hermosillo, Jad Nasrini, Sarah McGuire, Salil Saxena, Tyler M Moore, Ruben C Gur, David F Dinges
Study Objectives: The Psychomotor Vigilance Test (PVT) is reported to be free of practice effects that can otherwise confound the effects of sleep loss and circadian misalignment on performance. This differentiates the PVT from more complex cognitive tests. To our knowledge, no study has systematically investigated practice effects on the PVT across multiple outcome domains, depending on administration interval, and in ecologically more valid settings. Methods: We administered a validated 3-minute PVT (PVT-B) 16 times in 45 subjects (23 male, mean±SD age 32...
November 8, 2017: Sleep
https://www.readbyqxmd.com/read/29123651/recent-advances-in-managing-and-understanding-enuresis
#10
REVIEW
Charlotte Van Herzeele, Johan Vande Walle, Karlien Dhondt, Kristian Vinter Juul
Enuresis, particularly in children during sleep, can be a debilitating condition, affecting the quality of life of the child and his or her family. The pathophysiology of nocturnal enuresis, though not clear, revolves around the inter-related mechanisms of overactive bladder, excessive nocturnal urine production, and sleep fragmentation. The first mechanism is more related to isolated nocturnal voiding, whereas the latter two are more related to nocturnal enuresis, in which circadian variations in arginine vasopressin hormone play a key role...
2017: F1000Research
https://www.readbyqxmd.com/read/29113020/the-genetics-of-obstructive-sleep-apnoea
#11
REVIEW
Sutapa Mukherjee, Richa Saxena, Lyle J Palmer
Obstructive sleep apnoea (OSA) is a common chronic disease and is associated with high social and economic costs. OSA is heritable, and there is evidence of both direct genetic contributions to OSA susceptibility and indirect contributions via 'intermediate' phenotypes such as obesity, craniofacial structure, neurological control of upper airway muscles and of sleep and circadian rhythm. Investigation of the genetics of OSA is an important research area and may lead to improved understanding of disease aetiology, pathogenesis, adverse health consequences and new preventive strategies and treatments...
November 7, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29111816/comparing-the-response-to-acute-and-chronic-exposure-to-short-wavelength-lighting-emitted-from-computer-screens
#12
A Green, M Cohen-Zion, A Haim, Y Dagan
The use of electronic devices with light-emitting screens has increased exponentially in the last decade. As a result, humans are continuously exposed to unintentional artificial light. We explored the effects of acute and chronic exposure to artificial light at night (ALAN) via screen illumination on sleep, circadian rhythms, and related functional outcomes. Nineteen participants (11 female and 8 males, mean age 28.1 ± 7.2 years) underwent a six-night study with three experimental conditions using a repeated-measures design: baseline (first night, no light exposure), acute ALAN exposure (second night), and chronic ALAN exposure (third to sixth nights)...
November 7, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29111422/shorter-sleep-duration-and-longer-sleep-onset-latency-are-related-to-difficulty-disengaging-attention-from-negative-emotional-images-in-individuals-with-elevated-transdiagnostic-repetitive-negative-thinking
#13
Jacob A Nota, Meredith E Coles
BACKGROUND AND OBJECTIVES: Repetitive negative thinking (RNT) is often associated with disruptions in sleep and circadian rhythms. Disruptions in sleep and circadian rhythms may deal a "second hit" to attentional control deficits. This study evaluated whether sleep and circadian rhythm disruptions are related to the top-down control of attention to negative stimuli in individuals with heightened repetitive negative thinking. METHODS: Fifty-two community adults with high levels of transdiagnostic RNT and varying habitual sleep durations and bedtimes participated in a hybrid free-viewing and directed attention task using pairs of emotionally-evocative and neutral images while eye-tracking data were collected...
October 19, 2017: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/29109033/predicting-and-analyzing-early-wake-up-associated-gene-expressions-by-integrating-gwas-and-eqtl-studies
#14
JiaRui Li, Tao Huang
Circadian rhythms are endogenous 24-hour rhythmic oscillations affecting human behaviors, such as sleep, blood pressure and other biological processes, the disturbance of which lead to circadian rhythm sleep disorders (CRSDs). In this study, based on the data from genome-wide association studies (GWASs) and expression quantitative trait loci (eQTLs), we tried to identify novel gene expression patterns in brain tissues that were associated with early wake-up. First, the maximum-relevance-minimum-redundancy (mRMR) method was adopted to analyze the involved gene expression patterns, yielding a feature list...
November 3, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29108526/stabilising-sleep-for-patients-admitted-at-acute-crisis-to-a-psychiatric-hospital-owls-an-assessor-blind-pilot-randomised-controlled-trial
#15
Bryony Sheaves, Daniel Freeman, Louise Isham, Josephine McInerney, Alecia Nickless, Ly-Mee Yu, Stephanie Rek, Jonathan Bradley, Sarah Reeve, Caroline Attard, Colin A Espie, Russell Foster, Anna Wirz-Justice, Eleanor Chadwick, Alvaro Barrera
BACKGROUND: When patients are admitted onto psychiatric wards, sleep problems are highly prevalent. We carried out the first trial testing a psychological sleep treatment at acute admission (Oxford Ward sLeep Solution, OWLS). METHODS: This assessor-blind parallel-group pilot trial randomised patients to receive sleep treatment at acute crisis [STAC, plus standard care (SC)], or SC alone (1 : 1). STAC included cognitive-behavioural therapy (CBT) for insomnia, sleep monitoring and light/dark exposure for circadian entrainment, delivered over 2 weeks...
November 7, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/29107324/daytime-variation-of-perioperative-myocardial-injury-in-cardiac-surgery-and-its-prevention-by-rev-erb%C3%AE-antagonism-a-single-centre-propensity-matched-cohort-study-and-a-randomised-study
#16
David Montaigne, Xavier Marechal, Thomas Modine, Augustin Coisne, Stéphanie Mouton, Georges Fayad, Sandro Ninni, Cédric Klein, Staniel Ortmans, Claire Seunes, Charlotte Potelle, Alexandre Berthier, Celine Gheeraert, Catherine Piveteau, Rebecca Deprez, Jérome Eeckhoute, Hélène Duez, Dominique Lacroix, Benoit Deprez, Bruno Jegou, Mohamed Koussa, Jean-Louis Edme, Philippe Lefebvre, Bart Staels
BACKGROUND: On-pump cardiac surgery provokes a predictable perioperative myocardial ischaemia-reperfusion injury which is associated with poor clinical outcomes. We determined the occurrence of time-of-the-day variation in perioperative myocardial injury in patients undergoing aortic valve replacement and its molecular mechanisms. METHODS: We studied the incidence of major adverse cardiac events in a prospective observational single-centre cohort study of patients with severe aortic stenosis and preserved left ventricular ejection fraction (>50%) who were referred to our cardiovascular surgery department at Lille University Hospital (Lille, France) for aortic valve replacement and underwent surgery in the morning or afternoon...
October 26, 2017: Lancet
https://www.readbyqxmd.com/read/29106402/selective-neuronal-lapses-precede-human-cognitive-lapses-following-sleep-deprivation
#17
Yuval Nir, Thomas Andrillon, Amit Marmelshtein, Nanthia Suthana, Chiara Cirelli, Giulio Tononi, Itzhak Fried
Sleep deprivation is a major source of morbidity with widespread health effects, including increased risk of hypertension, diabetes, obesity, heart attack, and stroke. Moreover, sleep deprivation brings about vehicle accidents and medical errors and is therefore an urgent topic of investigation. During sleep deprivation, homeostatic and circadian processes interact to build up sleep pressure, which results in slow behavioral performance (cognitive lapses) typically attributed to attentional thalamic and frontoparietal circuits, but the underlying mechanisms remain unclear...
November 6, 2017: Nature Medicine
https://www.readbyqxmd.com/read/29106308/sleep-quality-and-methylation-status-of-core-circadian-rhythm-genes-among-nurses-and-midwives
#18
Agnieszka Bukowska-Damska, Edyta Reszka, Pawel Kaluzny, Edyta Wieczorek, Monika Przybek, Shanbeh Zienolddiny, Beata Peplonska
ABSTARCT Poor sleep quality or sleep restriction is associated with sleepiness and concentration problems. Moreover, chronic sleep restriction may affect metabolism, hormone secretion patterns and inflammatory responses. Limited recent reports suggest a potential link between sleep deprivation and epigenetic effects such as changes in DNA methylation profiles. The aim of the present study was to assess the potential association between poor sleep quality or sleep duration and the levels of 5-methylcytosine in the promoter regions of PER1, PER2, PER3, BMAL1, CLOCK, CRY1 CRY2 and NPAS2 genes, taking into account rotating night work and chronotype as potential confounders or modifiers...
November 6, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29105472/-effect-of-acupuncture-stimulation-of-different-acupoint-combinations-on-sleep-and-expression-of-circadian-clock-and-bmal-1-genes-in-hypothalamus-of-insomnia-rats
#19
Xin-Ran Wei, Gao-Wen Wei, Xue-Na Zheng, Xue-Fen Wu, Xiao-Li Chen, Li Liu, Qi-Qi Wen, Li-Na Xie, Zhi-Qiang Xie, Zeng-Hui Yue
OBJECTIVE: To observe the effect of manual acupuncture stimulation (MAS) of "Baihui"(GV 20)-"Shenmen"(HT 7)or GV 20-"Sanyinjiao"(SP 6) on sleep and expression of circadian rhythm genes (Clock and Bmal 1) in the hypothalamus in insomnia rats, so as to select a better acupoint group for insomnia. METHODS: A total of 53 SD rats were randomly divided into normal control (n=12),insomnia model (n=8), GV 20-HT 7(n=12), GV 20-SP 6(n=11),and GV 20-non-acupoint (n=10) groups...
October 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29104583/not-all-trees-sleep-the-same-high-temporal-resolution-terrestrial-laser-scanning-shows-differences-in-nocturnal-plant-movement
#20
András Zlinszky, Bence Molnár, Anders S Barfod
Circadian leaf movements are widely known in plants, but nocturnal movement of tree branches were only recently discovered by using terrestrial laser scanning (TLS), a high resolution three-dimensional surveying technique. TLS uses a pulsed laser emitted in a regular scan pattern for rapid measurement of distances to the targets, thus producing three dimensional point cloud models of sub-centimeter resolution and accuracy in a few minutes. Here, we aim to gain an overview of the variability of circadian movement of small trees across different taxonomic groups, growth forms and leaf anatomies...
2017: Frontiers in Plant Science
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