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https://www.readbyqxmd.com/read/28211649/insufficient-sleep-in-adolescents-causes-and-consequences
#1
Judith A Owens, Miriam R Weiss
Insufficient sleep poses an important and complicated set of health risks in the adolescent population. Not only is deficient sleep (defined as both sleep duration inadequate to meet sleep needs and sleep timing misaligned with the body's circadian rhythms) at epidemic levels in this population, but the contributing factors are both complex and numerous and there are a myriad of negative physical and mental health, safety and performance consequences. Causes of inadequate sleep identified in this population include internal biological processes such as the normal shift (delay) in circadian rhythm that occurs in association with puberty and a developmentally-based slowing of the "sleep drive", and external factors including extracurricular activities, excessive homework load, evening use of electronic media, caffeine intake and early school start times...
February 17, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28201795/implementation-science-in-sleep-medicine-commentary-on-parthasarathy-et-al-sleep-2016-39-12-2061-2075-implementation-of-sleep-and-circadian-science-recommendations-from-the-sleep-research-society-and-national-institutes-of-health-workshop
#2
https://www.readbyqxmd.com/read/28195837/the-effect-of-atomoxetin-use-in-the-treatment-of-attention-deficit-hyperactivity-disorder-on-the-symptoms-of-restless-legs-syndrome-a-case-report
#3
Saliha Baykal, Melih Nuri Karakurt
Attention-deficit/hyperactivity disorder (ADHD) is frequently accompanied with sleep disorders such as obstructive sleep apnea, periodic limb movement disorder, restless legs syndrome (RLS), and circadian rhythm disorder. We have limited information about the effects of medical therapies used in the treatment of ADHD on RLS. This article discusses the effects of atomoxetine treatment on both disorders in a patient followed by diagnoses of ADHD and RLS.
February 13, 2017: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/28181718/segmented-sleep-in-a-nonelectric-small-scale-agricultural-society-in-madagascar
#4
David R Samson, Melissa B Manus, Andrew D Krystal, Efe Fakir, James J Yu, Charles L Nunn
OBJECTIVES: We studied sleep in a rural population in Madagascar to (i) characterize sleep in an equatorial small-scale agricultural population without electricity, (ii) assess whether sleep is linked to noise levels in a dense population, and (iii) examine the effects of experimentally introduced artificial light on sleep timing. METHODS: Using actigraphy, sleep-wake patterns were analyzed for both daytime napping and nighttime wakefulness in 21 participants for a sum total of 292 days...
February 9, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28173893/sleep-and-circadian-rhythm-disturbance-in-bipolar-disorder
#5
A J Bradley, R Webb-Mitchell, A Hazu, N Slater, B Middleton, P Gallagher, H McAllister-Williams, K N Anderson
BACKGROUND: Subjective reports of insomnia and hypersomnia are common in bipolar disorder (BD). It is unclear to what extent these relate to underlying circadian rhythm disturbance (CRD). In this study we aimed to objectively assess sleep and circadian rhythm in a cohort of patients with BD compared to matched controls. METHOD: Forty-six patients with BD and 42 controls had comprehensive sleep/circadian rhythm assessment with respiratory sleep studies, prolonged accelerometry over 3 weeks, sleep questionnaires and diaries, melatonin levels, alongside mood, psychosocial functioning and quality of life (QoL) questionnaires...
February 8, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28173758/sleep-wake-movement-velocities-trajectories-and-micro-arousals-during-maturation-in-rats
#6
Gideon Gradwohl, Nadja Olini, Reto Huber
BACKGROUND: Sleep is regulated by two main processes. The circadian process provides a 24-h rhythm and the homeostatic process reflects sleep pressure, which increases in the course of wakefulness and decreases during sleep. Both of these processes undergo major changes during development. For example, sleep homeostasis, measured by means of electroencephalogram (EEG) slow-wave activity (SWA, EEG power between 0.5 and 4.5 Hz), peaks around puberty and decreases during adolescence. In humans and rats these changes have been related to cortical maturation...
February 7, 2017: BMC Neuroscience
https://www.readbyqxmd.com/read/28169885/repetitive-exposure-to-shortened-sleep-leads-to-blunted-sleep-associated-blood-pressure-dipping
#7
Huan Yang, Monika Haack, Shiva Gautam, Hans K Meier-Ewert, Janet M Mullington
BACKGROUND: Blood pressure (BP) dips at night during sleep in healthy individuals but in disturbed sleep, dipping is blunted. However, the impact of chronic insufficient sleep duration, with limited intermittent recovery sleep, on BP dipping is not known. The objective of this study was to examine, in a controlled experimental model, the influence of chronic sleep restriction on BP patterns at night and during the day. METHOD: In a highly controlled 22-day in-hospital protocol, 45 healthy participants (age 32 ± 2 years; BMI 24 ± 1 kg/m; 22 men and 23 women) were randomly assigned to one of two conditions: repeated sleep restriction (4 h of sleep/night from 0300 to 0700 h for three nights followed by recovery sleep of 8 h, repeated four times in succession) or a sleep control group (8 h/night from 2300 to 0700 h)...
February 6, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28169087/adolescents-at-clinical-high-risk-for-psychosis-circadian-rhythm-disturbances-predict-worsened-prognosis-at-1-year-follow-up
#8
Jessica R Lunsford-Avery, Bruno da Silva Brandão Gonçalves, Elisa Brietzke, Rodrigo A Bressan, Ary Gadelha, Randy P Auerbach, Vijay A Mittal
BACKGROUND: Individuals with psychotic disorders experience disruptions to both the sleep and circadian components of the sleep/wake cycle. Recent evidence has supported a role of sleep disturbances in emerging psychosis. However, less is known about how circadian rhythm disruptions may relate to psychosis symptoms and prognosis for adolescents with clinical high-risk (CHR) syndromes. The present study examines circadian rest/activity rhythms in CHR and healthy control (HC) youth to clarify the relationships among circadian rhythm disturbance, psychosis symptoms, psychosocial functioning, and the longitudinal course of illness...
February 4, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28164454/nutrition-movement-and-sleep-behaviours-their-interactions-in-pathways-to-obesity-and-cardiometabolic-diseases
#9
A G Dulloo, J L Miles-Chan, J-P Montani
Among the multitude of dietary and lifestyle behaviours that have been proposed to contribute to the obesity epidemic, those that have generated considerable research scrutiny in the past decade are centred upon sleep behaviours, sedentary behaviours (sitting or lying while awake) and diminished low-level physical activities of everyday life, with each category of behaviours apparently presenting an independent risk for obesity and/or cardiometabolic diseases. These behaviours are highly complex, operate in synergy with each other, disrupt the link between regulation of the circadian clock and metabolic physiology and impact on various components of daily energy expenditure and feeding behaviours to promote obesity and hinder the outcome of obesity therapy...
February 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28164449/role-of-sleep-and-circadian-disruption-on-energy-expenditure-and-in-metabolic-predisposition-to-human-obesity-and-metabolic-disease
#10
REVIEW
A W McHill, K P Wright
Weight gain, obesity and diabetes have reached alarming levels in the developed world. Traditional risk factors such as over-eating, poor nutritional choices and lack of exercise cannot fully account for the high prevalence of metabolic disease. This review paper examines the scientific evidence on two novel risk factors that contribute to dys-regulated metabolic physiology: sleep disruption and circadian misalignment. Specifically, fundamental relationships between energy metabolism and sleep and circadian rhythms and the impact of sleep and circadian disruption on metabolic physiology are examined...
February 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28162920/how-does-general-anaesthesia-affect-the-circadian-clock
#11
REVIEW
Raewyn C Poulsen, Guy R Warman, Jamie Sleigh, Nicola M Ludin, James F Cheeseman
: Post-operative patients experience sleep disturbances. Animal studies demonstrate that general anaesthesia (GA) can disrupt circadian rhythms and cause changes in the molecular clock, indicating that anaesthesia contributes to post-operative circadian disruption. Here we review the effect of anaesthesia on the circadian clock and its rhythms in order to summarise current findings outline commonalities between studies and propose mechanisms by which effects may be mediated. KEY POINTS: 1) GA has strong effects on the main neurotransmitter systems linked with circadian control (Gamma aminobutyric acid/N-methyl-D-aspartate (GABA/NMDA)) and may act by interfering with light-entrainment of the clock...
December 18, 2016: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/28162893/circadian-entrainment-to-the-natural-light-dark-cycle-across-seasons-and-the-weekend
#12
Ellen R Stothard, Andrew W McHill, Christopher M Depner, Brian R Birks, Thomas M Moehlman, Hannah K Ritchie, Jacob R Guzzetti, Evan D Chinoy, Monique K LeBourgeois, John Axelsson, Kenneth P Wright
Reduced exposure to daytime sunlight and increased exposure to electrical lighting at night leads to late circadian and sleep timing [1-3]. We have previously shown that exposure to a natural summer 14 hr 40 min:9 hr 20 min light-dark cycle entrains the human circadian clock to solar time, such that the internal biological night begins near sunset and ends near sunrise [1]. Here we show that the beginning of the biological night and sleep occur earlier after a week's exposure to a natural winter 9 hr 20 min:14 hr 40 min light-dark cycle as compared to the modern electrical lighting environment...
February 2, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28160289/melanopsin-expressing-human-retinal-ganglion-cells-subtypes-distribution-and-intraretinal-connectivity
#13
Jens Hannibal, Anders Tolstrup Christensen, Steffen Heegaard, Jan Fahrenkrug, Jens Folke Kiilgaard
Intrinsically photosensitive retinal ganglion cells (ipRGCs) expressing the photopigment melanopsin belong to a heterogenic population of RGCs which regulate the circadian clock, masking behavior, melatonin suppression, the pupillary light reflex and sleep/wake cycles. The different functions seem to be associated to different subtypes of melanopsin cells. In rodents, subtype classification has associated subtypes to function. In primate and human retina such classification has so far, not been applied. In the present study using antibodies against N- and C-terminal parts of human melanopsin, confocal microscopy and 3D reconstruction of melanopsin immunoreactive (-ir) RGCs, we applied the criteria used in mouse on human melanopsin-ir RGCs...
February 3, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28160224/examining-the-behavioural-sleep-wake-rhythm-in-adults-with-autism-spectrum-disorder-and-no-comorbid-intellectual-disability
#14
Emma K Baker, Amanda L Richdale
This study aimed to examine the behavioural sleep-wake rhythm in 36 adults with autism spectrum disorder (ASD) and to determine the prevalence of circadian sleep-wake rhythm disorders compared to age- and sex-matched controls. Participants completed an online questionnaire battery, a 14-day sleep-wake diary and 14-day actigraphy assessment. The results indicated that a higher proportion of adults with ASD met criteria for a circadian rhythm sleep-wake disorder compared to control adults. In particular, delayed sleep-wake phase disorder was particularly common in adults with ASD...
February 3, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28155201/dad-s-snoring-may-have-left-molecular-scars-in-your-dna-the-emerging-role-of-epigenetics-in-sleep-disorders
#15
REVIEW
Daniela Morales-Lara, Clelia De-la-Peña, Eric Murillo-Rodríguez
The sleep-wake cycle is a biological phenomena under the orchestration of neurophysiological, neurochemical, neuroanatomical, and genetical mechanisms. Moreover, homeostatic and circadian processes participate in the regulation of sleep across the light-dark period. Further complexity of the understanding of the genesis of sleep engages disturbances which have been characterized and classified in a variety of sleep-wake cycle disorders. The most prominent sleep alterations include insomnia as well as excessive daytime sleepiness...
February 2, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28154744/environmental-factors-influencing-biological-rhythms-in-newborns-from-neonatal-intensive-care-units-to-home
#16
Clarissa Bueno, Luiz Menna-Barreto
Photic and non-photic environmental factors are suggested to modulate the development of circadian rhythms in infants. Our aim is to evaluate the development of biological rhythms (circadian or ultradian) in newborns in transition from Neonatal Intensive Care Units (NICU) to home and along the first 6 months of life, to identify masking and entraining environment factors along development. Ten newborns were evaluated in their last week inside the NICU and in the first week after being delivered home; 6 babies were also followed until 6 months of corrected age...
October 2016: Sleep Science
https://www.readbyqxmd.com/read/28154740/comparative-analysis-of-actigraphy-performance-in-healthy-young-subjects
#17
Giannina J Bellone, Santiago A Plano, Daniel P Cardinali, Daniel Pérez Chada, Daniel E Vigo, Diego A Golombek
Sleep-related health disorders are increasing worldwide; diagnosis and treatment of such sleep diseases are commonly invasive and sometimes unpractical or expensive. Actigraphy has been recently introduced as a tool for the study of sleep and circadian disorders; however, there are several devices that claim to be useful for research and have not been thoroughly tested. This comparative study provides activity, sleep and temperature information regarding several of the most commonly used actigraphers: Micro-Mini Motion Logger; Act Trust; Misfit Flash; Fitbit Flex & Thermochron...
October 2016: Sleep Science
https://www.readbyqxmd.com/read/28153210/sleep-habits-circadian-preference-and-school-performance-in-early-adolescents
#18
Paolo M Russo, Valeria Biasi, Carlo Cipolli, Luca Mallia, Elisa Caponera
OBJECTIVE: This study aimed to cast light on the relationships between sleep habits, perceived sleep problems and school performance in Evening-type (E-type) compared with Morning-type (M-type) early adolescents. METHODS: Comparison of questionnaire data of E-type and M-type adolescents random-selected from a large sample of eight-grade adolescents who took part in a national survey of competence in mathematics and science. RESULTS: The proportions of sleep problems that were observed to occur more than once per week and the frequency of struggling to fall asleep and/or falling asleep in distinct everyday situations were much higher in E-type than in M-type adolescents...
January 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28145903/the-aging-clock-circadian-rhythms-and-later-life
#19
REVIEW
Suzanne Hood, Shimon Amir
Circadian rhythms play an influential role in nearly all aspects of physiology and behavior in the vast majority of species on Earth. The biological clockwork that regulates these rhythms is dynamic over the lifespan: rhythmic activities such as sleep/wake patterns change markedly as we age, and in many cases they become increasingly fragmented. Given that prolonged disruptions of normal rhythms are highly detrimental to health, deeper knowledge of how our biological clocks change with age may create valuable opportunities to improve health and longevity for an aging global population...
February 1, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28140399/timing-of-light-exposure-affects-mood-and-brain-circuits
#20
REVIEW
T A Bedrosian, R J Nelson
Temporal organization of physiology is critical for human health. In the past, humans experienced predictable periods of daily light and dark driven by the solar day, which allowed for entrainment of intrinsic circadian rhythms to the environmental light-dark cycles. Since the adoption of electric light, however, pervasive exposure to nighttime lighting has blurred the boundaries of day and night, making it more difficult to synchronize biological processes. Many systems are under circadian control, including sleep-wake behavior, hormone secretion, cellular function and gene expression...
January 31, 2017: Translational Psychiatry
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