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PT 003

Chien-Min Chen, Meng Lee, Chia-Hung Lin, Chia-Hao Chang, Chu-Hsu Lin
The first choice of treatment for patients with plantar fasciitis is non-invasive treatment, rather than corticosteroid injection (CSI). However, no comprehensive study has compared the effectiveness of CSI with non-invasive treatments for plantar fasciitis. We conducted a meta-analysis comparing CSI and non-invasive treatment effects on plantar fasciitis. The primary outcome was pain reduction. Nine randomized controlled trials comparing CSI with 4 non-invasive treatment types were included. A trend favoring CSI over non-invasive treatments was indicated regarding reduction in the visual analogue scale (VAS) score at 1-1...
March 5, 2018: Scientific Reports
Yuan Li, Jian-An Ren, Ge-Fei Wang, Guo-Sheng Gu, Xiu-Wen Wu, Song Liu, Hua-Jian Ren, Zhi-Wu Hong, Jie-Shou Li
Background: Intestinal fistula is one of the common complications of Crohn's disease (CD) that might require surgical treatment. The clinical characteristics and outcomes of CD with intestinal fistula are much different from CD alone. This study was to investigate whether the coagulation status of CD is changed by intestinal fistula. Methods: Data were retrospectively analyzed for 190 patients with a definitive diagnosis of CD who were registered at the Jinling Hospital between January 2014 and September 2015...
March 5, 2018: Chinese Medical Journal
Zhixiong Chen, Shengjun Luo, Yanlin Chen, Xuemei Xie, Zhongbo Du, Li Jiang
As a tumor suppressor candidate gene, NPRL2 has anti-cancer effects against several cancers, but its potential role in prostate cancer (PCa) has not been reported. The present study aimed to explore the expression of NPRL2 in PCa and its potential clinical significance. Our results showed that expression of NPRL2 in PCa tissues was significantly higher than in non-PCa tissues (P<.001). High NPRL2 expression in PCa tissue was significantly correlated with a high Gleason grade group (P<.001), high pT stage (P<...
February 16, 2018: Human Pathology
Rosa Zampino, Rita Lebano, Nicola Coppola, Margherita Macera, Anna Grandone, Luca Rinaldi, Ilario De Sio, Antonella Tufano, Gianfranca Stornaiuolo, Luigi E Adinolfi, Emanuele Durante-Mangoni, Gaeta G Battista, Alferio Niglio
Background/Aim: A reduction in portal vein inflow velocity seems to predispose to the emergence of portal vein thrombosis (PVT). Nonselective β-blockers (NSBBs), used to prevent variceal bleeding, may increase the development of PVT by reducing portal vein inflow velocity. In this retrospective case-control study, we evaluated the risk factors and clinical features of a first event of PVT in 130 cirrhotics, 19 (15%) with (PVT group) and 111 (85%) without PVT (non-PVT group). Patients and Methods: Patient evaluation and NNBB treatment were carried out according to the AASLD guidelines...
January 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
Giuseppe Marulli, Enrico Verderi, Giovanni M Comacchio, Nicola Monaci, Giuseppe Natale, Samuele Nicotra, Federico Rea
Background: In the last decades, the use of video-assisted thoracoscopic surgery (VATS) lobectomy for the treatment of early stage non-small cell lung cancer is continuously growing. This is mainly due to the development of more advanced surgical devices, to the rising incidence of peripheral lung tumors and is also favored by the increased reliability of preoperative staging techniques. Despite this progress, postoperative unexpected nodal upstaging is still a relevant issue. Aim of this study is to identify possible predictors of unexpected nodal upstaging in patients affected by cT1-3N0 NSCLC submitted to VATS lobectomy...
2018: Journal of Visualized Surgery
Rashad Zayat, Mohamed Shoaib, Mohammad Amen Khattab, Usaama Ahmad, Andreas Goetzenich, Christian Stoppe, Ann Christina Foldenauer, Ajay Moza, Heike Schnoering, Rüdiger Autschbach, Lachmandath Tewarie
OBJECTIVES: Haemolysis during left ventricular assist device support is associated with thrombosis. In this retrospective study, we analysed whether low-level haemolysis (LLH) as defined by simultaneously elevated lactate dehydrogenase (LDH) and free haemoglobin (fHb) levels had an impact on thromboembolic and bleeding events and on von Willebrand factor levels in HeartMate II patients. METHODS: After exclusion of patients with LDH >700 U/l and fHb >40 mg/dl at hospital discharge, 79 HeartMate II patients were included...
February 12, 2018: Interactive Cardiovascular and Thoracic Surgery
Sunita Seshia, M Casey Gaunt, Beverly A Kidney, Marion L Jackson
BACKGROUND: Evidence suggests that administration of intravenous fluids impairs hemostasis. Thromboelastometry (TEM) may provide a more sensitive measure of the fluid effects on hemostasis than traditional coagulation tests. OBJECTIVE: The study aim was to determine if resuscitative fluid therapy affects hemostasis, as measured by TEM. MATERIALS AND METHODS: Using a randomized crossover design, 6 healthy dogs were administered intravenous colloid, crystalloid, and hypertonic saline at therapeutic doses...
February 11, 2018: Veterinary Clinical Pathology
Marcin Grześkowiak, Zbigniew Krawiecki, Wojciech Łabędź, Jacek Kaczmarczyk, Jacek Lewandowski, Dawid Łochyński
CONTEXT: Kinesio taping® (KT) is a therapeutic modality frequently used in the clinical practice for the treatment of various musculoskeletal disorders. It is often applied in patients with chronic low back pain (CLBP) to decrease pain and improve functional capacity. However, it is not known, whether thoracolumbar fascia Kinesio Taping® (KT) technique can decrease back pain, restore normal activity of paraspinal muscles and improve functional capacity in patients with lumbar disc herniation (LDH)...
February 6, 2018: Journal of Sport Rehabilitation
Jacopo Mariotti, Raynier Devillier, Stefania Bramanti, Barbara Sarina, Sabine Furst, Angela Granata, Catherine Faucher, Samia Harbi, Lucio Morabito, Christian Chabannon, Carmelo Carlo-Stella, Reda Bouabdallah, Armando Santoro, Didier Blaise, Luca Castagna
Allogeneic hematopoietic stem cell transplantation (SCT) represents a potential curative strategy for patients with Hodgkin lymphoma (HL) relapsing after autologous SCT (ASCT), but the incidence of disease relapse is still high. We performed a retrospective study on 64 patients with HL relapsing after ASCT to compare outcomes after HLA-identical SCT (HLAid-SCT; n = 34) and haploidentical SCT with post-transplantation cyclophosphamide (PT-Cy) (Haplo-SCT; n = 30). All patients engrafted, with a significantly shorter median time for neutrophil and platelet engraftment after HLAid compared with Haplo-SCT (14 days versus 19 days and 11 days versus 23 days, respectively; P < ...
March 2018: Biology of Blood and Marrow Transplantation
Adolfo Di Fiore, Stefano Sivolella, Elena Stocco, Vittorio Favero, Edoardo Stellini
The implant site preparation through drilling procedures may cause bone thermonecrosis. The aim of this in vitro study was to evaluate, using a thermal probe, the overheating at implant sites during osteotomies through two different drilling methods (continuous drilling technique versus intermittent drilling technique) using irrigation at different temperatures. Five implant sites of 13mm in length were performed on sixteen blocks (fresh bovine ribs), for a total amount of 80 implant sites. The thermal probe PT-100 was positioned at 5 mm from each site...
November 14, 2017: Journal of Oral Implantology
Won Gi Hong, Young San Ko, Jung-Soo Pyo
OBJECTIVE: The aim of this study was to elucidate the clinicopathological significance and prognostic role of microvessel density (MVD) in gastric cancer (GC) through a meta-analysis. METHODS: This meta-analysis included 4094 patients from 26 eligible studies. We investigated the correlation between MVD and clinicopathological characteristics, including survival rate. In addition, subgroup analysis based on microscopic magnification among evaluation criteria of MVD was performed...
November 8, 2017: Pathology, Research and Practice
Olivier Maurelli, Pierre Louis Bernard, Romain Dubois, Said Ahmaidi, Jacques Prioux
The aim of this study was to describe the effects of eight weeks of pre-competitive period preparation (Pc2P) on the isokinetic muscular characteristics in world-class handball players. Nineteen male professional players (age: 26.6 ± 5.4 years) participated in the study. Two bilateral isokinetic tests of knee joint flexors (H; Hamstring) and extensors (Q; Quadriceps) were performed before and after Pc2P to determine the peak torque (PT), the mean power (MP) and the ratios (agonist/antagonist, dominant/non-dominant and combined)...
October 20, 2017: Journal of Strength and Conditioning Research
Aldo Brassetti, Riccardo Lombardo, Paolo Emiliozzi, Antonio Cardi, De Vico Antonio, Iannello Antonio, Scapellato Aldo, Riga Tommaso, Pansadoro Alberto, D'Elia Gianluca
OBJECTIVES: To analyse the performance of Prostate specific antigen density (PSAD) as a predictor of upstaging and Prognostic Grade Group (PGG) upgrading. METHODS: we retrospectively evaluated data on men with prostate PCa treated with robotic radical prostatectomy (RALP) at our center in 2014-2015. Preoperative PSAD was calculated. Bioptic and pathologic PGGs were also considered in the analysis. We defined upgrading any increase in PGG after RALP; upstaging was the pathological diagnosis of a pT≥3a PCa clinically unsuspected...
October 12, 2017: Urology
Richard M Page, Kelly Marrin, Chris M Brogden, Matt Greig
The aim of this study was to assess the physiological, perceptual, and mechanical measures associated with the completion of a simulated period of short-term soccer-specific fixture congestion. Ten male semi-professional soccer players completed three trials of a treadmill-based match simulation, with 48 hours intervening each trial. A repeated measures general linear model identified significantly (P= 0.02) lower knee flexor peak torque (PT) recorded at 300 degs[BULLET OPERATOR]s in the second (141.27 ± 28...
October 10, 2017: Journal of Strength and Conditioning Research
Sonay Kuş Öztürk, Esra Erden
OBJECTIVE: Pancreatic ductal adenocarcinoma is an aggressive tumor with short survival. In this study we aimed to investigate the effect of well-known prognostic parameters on survival in these tumors. MATERIAL AND METHOD: A total of 56 pancreatic ductal adenocarcinoma cases diagnosed between 2005 and 2014 were included in the study. Survival data were obtained and histopathological parameters were re-evaluated in each patient. RESULTS: Tumor size (p=0...
October 6, 2017: Türk Patoloji Dergisi
Kristbjörg Sveinsdóttir, John-Kalle Länsberg, Snjólaug Sveinsdóttir, Martin Garwicz, Lennart Ohlsson, Ann Hellström, Lois Smith, Magnus Gram, David Ley
Cerebellar growth is impeded following very preterm birth in human infants and the observed reduction in cerebellar volume is associated with neurodevelopmental impairment. Decreased levels of circulating insulin-like growth factor 1 (IGF-1) are associated with decreased cerebellar volume. The relationship between preterm birth, circulating IGF-1, and key cell populations supporting cerebellar proliferation is unknown. The aim of this study was to evaluate the effect of preterm birth on postnatal growth, circulating IGF-1, and cerebellar maturation in a preterm rabbit pup model...
October 4, 2017: Developmental Neuroscience
Jean Robert Delpero, Florence Jeune, Philippe Bachellier, Nicolas Regenet, Yves Patrice Le Treut, Francois Paye, Nicolas Carrere, Alain Sauvanet, Mustapha Adham, Aurelie Autret, Flora Poizat, Olivier Turrini, Jean Marie Boher
OBJECTIVE: The aim of the study was to assess the relevance of resection margin status for survival after resection of pancreatic-head ductal adenocarcinoma. SUMMARY BACKGROUND DATA: The definition and prognostic value of incomplete microscopic resection (R1) remain controversial. METHODS: Prognostic factors were analyzed in 147 patients included in a prospective multicenter study on the impact of tumor clearance evaluated using a standardized pathology protocol...
November 2017: Annals of Surgery
Gena R Gerstner, Hayden K Giuliani, Jacob A Mota, Eric D Ryan
Age-related changes in the relative differences in isokinetic strength and power may reflect fast twitch fiber function. We aimed to examine the influence of muscle quality on the relative differences in strength and power in younger and older men. Twenty younger (20.1±1.5yrs) and 20 older (69.5±3.1yrs) healthy, recreationally active men performed two plantarflexion maximal voluntary isometric contractions (MVCs) and three maximal concentric isokinetic contractions at a slow (0.52rad·s(-1)) and fast (2.09rad·s(-1)) velocity...
December 1, 2017: Experimental Gerontology
Hojjat Derakhshanfar, Ali Vafaei, Ali Tabatabaey, Shamila Noori
INTRODUCTION: Acute traumatic coagulopathy (ATC) is defined as having evidence of coagulopathy in patients with severe trauma. The aim of this preliminary study was to assess the prevalence and associated factors of ATC in severely traumatic patients presenting to emergency department (ED). METHODS: In this retrospective cross sectional study, all patients with severe traumatic injury and available coagulation profile, presenting to the EDs of two major trauma centers in Tehran, Iran, during one year, were studied...
2017: Emergency (Tehran, Iran)
Okan Ozkunt, Gökhan Karademir, Kerim Sariyilmaz, Halil Can Gemalmaz, Fatih Dikici, Unsal Domanic
OBJECTIVE: The aim of this study was to evaluate preoperative and postoperative spinopelvic parameters and the influence of lowest instrumented vertebrae on sagittal parameters in Lenke 5 Adolescent Idiopathic Scoliosis (AIS) patients. METHODS: A total of 42 patients (37 females, 5 males; mean age: 16.71 ± 3.46 years) were included in the study. Preoperative and postoperative last follow up lumbar lordosis (LL), thoracic kyphosis (TK), pelvic tilt (PT), pelvic incidence (PI) and sacral slope (SS) angles measured...
September 7, 2017: Acta Orthopaedica et Traumatologica Turcica
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