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https://www.readbyqxmd.com/read/29135381/experimental-analysis-of-temperature-differences-during-implant-site-preparation-continuous-drilling-technique-versus-intermittent-drilling-technique
#1
Adolfo Di Fiore, Stefano Sivolella, Elena Stocco, Vittorio Favero, Edoardo Stellini
The implant site preparation through drilling procedures may cause bone thermonecrosis. The aim of this in vitro study was to evaluate, using a thermal probe, the overheating at implant sites during osteotomies through two different drilling methods (continuous drilling technique versus intermittent drilling technique) using irrigation at different temperatures. Five implant sites of 13mm in length were performed on sixteen blocks (fresh bovine ribs), for a total amount of 80 implant sites. The thermal probe PT-100 was positioned at 5 mm from each site...
November 14, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29129495/clinicopathological-significance-and-prognostic-role-of-microvessel-density-in-gastric-cancer-a-meta-analysis
#2
Won Gi Hong, Young San Ko, Jung-Soo Pyo
OBJECTIVE: The aim of this study was to elucidate the clinicopathological significance and prognostic role of microvessel density (MVD) in gastric cancer (GC) through a meta-analysis. METHODS: This meta-analysis included 4094 patients from 26 eligible studies. We investigated the correlation between MVD and clinicopathological characteristics, including survival rate. In addition, subgroup analysis based on microscopic magnification among evaluation criteria of MVD was performed...
November 8, 2017: Pathology, Research and Practice
https://www.readbyqxmd.com/read/29076959/effects-of-pre-competitive-preparation-period-on-the-isokinetic-muscular-characteristics-in-world-class-handball-players
#3
Olivier Maurelli, Pierre Louis Bernard, Romain Dubois, Said Ahmaidi, Jacques Prioux
The aim of this study was to describe the effects of eight weeks of pre-competitive period preparation (Pc2P) on the isokinetic muscular characteristics in world-class handball players. Nineteen male professional players (age: 26.6 ± 5.4 years) participated in the study. Two bilateral isokinetic tests of knee joint flexors (H; Hamstring) and extensors (Q; Quadriceps) were performed before and after Pc2P to determine the peak torque (PT), the mean power (MP) and the ratios (agonist/antagonist, dominant/non-dominant and combined)...
October 20, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29032238/psa-density-is-a-good-predictor-of-upstaging-and-upgrading-according-to-the-new-grading-system-the-keys-we-are-seeking-may-be-already-in-our-pocket
#4
Aldo Brassetti, Riccardo Lombardo, Paolo Emiliozzi, Antonio Cardi, De Vico Antonio, Iannello Antonio, Scapellato Aldo, Riga Tommaso, Pansadoro Alberto, D'Elia Gianluca
OBJECTIVES: To analyse the performance of Prostate specific antigen density (PSAD) as a predictor of upstaging and Prognostic Grade Group (PGG) upgrading. METHODS: we retrospectively evaluated data on men with prostate PCa treated with robotic radical prostatectomy (RALP) at our center in 2014-2015. Preoperative PSAD was calculated. Bioptic and pathologic PGGs were also considered in the analysis. We defined upgrading any increase in PGG after RALP; upstaging was the pathological diagnosis of a pT≥3a PCa clinically unsuspected...
October 12, 2017: Urology
https://www.readbyqxmd.com/read/29023324/the-physical-response-to-a-simulated-period-of-soccer-specific-fixture-congestion
#5
Richard M Page, Kelly Marrin, Chris M Brogden, Matt Greig
The aim of this study was to assess the physiological, perceptual, and mechanical measures associated with the completion of a simulated period of short-term soccer-specific fixture congestion. Ten male semi-professional soccer players completed three trials of a treadmill-based match simulation, with 48 hours intervening each trial. A repeated measures general linear model identified significantly (P= 0.02) lower knee flexor peak torque (PT) recorded at 300 degs[BULLET OPERATOR]s in the second (141.27 ± 28...
October 10, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28984346/do-the-well-known-prognostic-parameters-in-pancreatic-ductal-adenocarcinoma-really-reflect-survival
#6
Sonay Kuş Öztürk, Esra Erden
OBJECTIVE: Pancreatic ductal adenocarcinoma is an aggressive tumor with short survival. In this study we aimed to investigate the effect of well-known prognostic parameters on survival in these tumors. MATERIAL AND METHOD: A total of 56 pancreatic ductal adenocarcinoma cases diagnosed between 2005 and 2014 were included in the study. Survival data were obtained and histopathological parameters were re-evaluated in each patient. RESULTS: Tumor size (p=0...
October 6, 2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28972955/impaired-cerebellar-maturation-growth-restriction-and-circulating-insulin-like-growth-factor-1-in-preterm-rabbit-pups
#7
Kristbjörg Sveinsdóttir, John-Kalle Länsberg, Snjólaug Sveinsdóttir, Martin Garwicz, Lennart Ohlsson, Ann Hellström, Lois Smith, Magnus Gram, David Ley
Cerebellar growth is impeded following very preterm birth in human infants and the observed reduction in cerebellar volume is associated with neurodevelopmental impairment. Decreased levels of circulating insulin-like growth factor 1 (IGF-1) are associated with decreased cerebellar volume. The relationship between preterm birth, circulating IGF-1, and key cell populations supporting cerebellar proliferation is unknown. The aim of this study was to evaluate the effect of preterm birth on postnatal growth, circulating IGF-1, and cerebellar maturation in a preterm rabbit pup model...
October 4, 2017: Developmental Neuroscience
https://www.readbyqxmd.com/read/28953554/prognostic-value-of-resection-margin-involvement-after-pancreaticoduodenectomy-for-ductal-adenocarcinoma-updates-from-a-french-prospective-multicenter-study
#8
MULTICENTER STUDY
Jean Robert Delpero, Florence Jeune, Philippe Bachellier, Nicolas Regenet, Yves Patrice Le Treut, Francois Paye, Nicolas Carrere, Alain Sauvanet, Mustapha Adham, Aurelie Autret, Flora Poizat, Olivier Turrini, Jean Marie Boher
OBJECTIVE: The aim of the study was to assess the relevance of resection margin status for survival after resection of pancreatic-head ductal adenocarcinoma. SUMMARY BACKGROUND DATA: The definition and prognostic value of incomplete microscopic resection (R1) remain controversial. METHODS: Prognostic factors were analyzed in 147 patients included in a prospective multicenter study on the impact of tumor clearance evaluated using a standardized pathology protocol...
November 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28927901/age-related-reductions-in-muscle-quality-influence-the-relative-differences-in-strength-and-power
#9
Gena R Gerstner, Hayden K Giuliani, Jacob A Mota, Eric D Ryan
Age-related changes in the relative differences in isokinetic strength and power may reflect fast twitch fiber function. We aimed to examine the influence of muscle quality on the relative differences in strength and power in younger and older men. Twenty younger (20.1±1.5yrs) and 20 older (69.5±3.1yrs) healthy, recreationally active men performed two plantarflexion maximal voluntary isometric contractions (MVCs) and three maximal concentric isokinetic contractions at a slow (0.52rad·s(-1)) and fast (2.09rad·s(-1)) velocity...
December 1, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28920070/prevalence-and-associated-factors-of-acute-traumatic-coagulopathy-a-cross-sectional-study
#10
Hojjat Derakhshanfar, Ali Vafaei, Ali Tabatabaey, Shamila Noori
INTRODUCTION: Acute traumatic coagulopathy (ATC) is defined as having evidence of coagulopathy in patients with severe trauma. The aim of this preliminary study was to assess the prevalence and associated factors of ATC in severely traumatic patients presenting to emergency department (ED). METHODS: In this retrospective cross sectional study, all patients with severe traumatic injury and available coagulation profile, presenting to the EDs of two major trauma centers in Tehran, Iran, during one year, were studied...
2017: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/28889983/analysing-the-change-of-sagittal-balance-in-patients-with-lenke-5-idiopathic-scoliosis
#11
Okan Ozkunt, Gökhan Karademir, Kerim Sariyilmaz, Halil Can Gemalmaz, Fatih Dikici, Unsal Domanic
OBJECTIVE: The aim of this study was to evaluate preoperative and postoperative spinopelvic parameters and the influence of lowest instrumented vertebrae on sagittal parameters in Lenke 5 Adolescent Idiopathic Scoliosis (AIS) patients. METHODS: A total of 42 patients (37 females, 5 males; mean age: 16.71 ± 3.46 years) were included in the study. Preoperative and postoperative last follow up lumbar lordosis (LL), thoracic kyphosis (TK), pelvic tilt (PT), pelvic incidence (PI) and sacral slope (SS) angles measured...
September 7, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28880458/determinants-of-platelet-count-in-pediatric-patients-with-congenital-cyanotic-heart-disease-role-of-immature-platelet-fraction
#12
Randa M Matter, Iman A Ragab, Alaa M Roushdy, Ahmed G Ahmed, Hanan H Aly, Eman A Ismail
OBJECTIVES: Congenital heart defects are common noninfectious causes of mortality in children. Bleeding and thrombosis are both limiting factors in the management of such patients. We assessed the frequency of thrombocytopenia in pediatric patients with congenital cyanotic heart disease (CCHD) and evaluated determinants of platelet count including immature platelet fraction (IPF) and their role in the pathogenesis of thrombocytopenia. METHODS: Forty-six children and adolescents with CCHD during pre-catheter visits were studied; median age was 20...
September 7, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28862264/sox2-silenced-squamous-cell-carcinoma-a-highly-malignant-form-of-esophageal-cancer-with-sox2-promoter-hypermethylation
#13
Ritsuko Maehara, Kohei Fujikura, Kengo Takeuchi, Masayuki Akita, Shiho Abe-Suzuki, Jana Karbanová, Denis Corbeil, Tomoo Itoh, Yoshihiro Kakeji, Yoh Zen
This study originally aimed to investigate whether the overexpression of SOX2 is associated with the poor prognosis of patients with squamous cell carcinoma of the esophagus. However, we unexpectedly found that esophageal squamous cell carcinomas completely lacking SOX2 expression showed distinct pathologic features and highly aggressive clinical courses. The study cohort consisted of 113 consecutive patients with esophageal squamous cell carcinoma who underwent surgical resection without neoadjuvant therapy...
September 1, 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28804763/effects-of-chest-physical-therapy-in-patients-with-non-tuberculous-mycobacteria
#14
Ashwin Basavaraj, Leopoldo Segal, Jonathan Samuels, Jeremy Feintuch, Joshua Feintuch, Kevin Alter, Daniella Moffson, Adrienne Scott, Doreen Addrizzo-Harris, Mengling Liu, David Kamelhar
Antibiotic therapy against non-tuberculous mycobacteria (NTM) is prolonged and can be associated with toxicity. We sought to evaluate whether chest physical therapy (PT) was associated with clinical improvement in patients with NTM not receiving anti-mycobacterial pharmacotherapy. A retrospective review of 77 subjects that were followed from June 2006 to September 2014 was performed. Baseline time point was defined as the first positive sputum culture for NTM; symptoms, pulmonary function, and radiology reports were studied...
2017: International Journal of Respiratory and Pulmonary Medicine
https://www.readbyqxmd.com/read/28698535/is-post-treatment-standardized-uptake-value-a-prognostic-factor-in-unresectable-non-small-cell-lung-carcinoma
#15
Ufuk Yılmaz, Zehra Yasar, Esra Korkmaz, Burcu Yalcın, Hakan Koparal, Engin Ozbilek
Aim Concurrent chemoradiotherapy (CRT) is the standard of care for locally advanced, unresectable non-small cell lung carcinoma (NSCLC). The aim of this study was to assess the prognostic value of maximum standardized uptake values (SUVmax) in patients with unresectable stage III NSCLC treated with concurrent CRT. Method 18F-FDG PET-CT scans were obtained before and after treatment in patients with unresectable stage III NSCLC treated with concurrent CRT. To determine the prognostic value of SUVmax of the primary tumor (PT), univariate and multivariate Cox regression model were carried out...
August 1, 2017: Medicinski Glasnik
https://www.readbyqxmd.com/read/28668287/prognostic-value-of-pd-1-and-pd-l1-expression-in-patients-with-high-grade-upper-tract-urothelial-carcinoma
#16
Laura-Maria Krabbe, Barbara Heitplatz, Sina Preuss, Ryan C Hutchinson, Solomon L Woldu, Nirmish Singla, Martin Boegemann, Christopher G Wood, Jose A Karam, Alon Z Weizer, Jay D Raman, Mesut Remzi, Nathalie Rioux-Leclercq, Andrea Haitel, Leonid M Rapoport, Peter V Glybochko, Marco Roscigno, Christian Bolenz, Karim Bensalah, Arthur I Sagalowsky, Shahrokh F Shariat, Yair Lotan, Evanguelos Xylinas, Vitaly Margulis
PURPOSE: We investigated the prognostic value of PD-1 and PD-L1 expression in patients with high grade upper tract urothelial carcinoma. MATERIALS AND METHODS: Tissue microarrays of 423 patients treated with extirpative surgery for high grade upper tract urothelial carcinoma from the International Upper Tract Urothelial Carcinoma collaboration were stained for PD-1 and PD-L1 using antibodies, including Cell Marque™ NAT105 diluted 1:250 and prediluted E1L3N® via immunohistochemistry...
December 2017: Journal of Urology
https://www.readbyqxmd.com/read/28627000/pencil-beam-scanned-protons-for-the-treatment-of-patients-with-ewing-sarcoma
#17
Damien C Weber, Fritz R Murray, Dora Correia, Alessandra Bolsi, Martina Frei-Welte, Alessia Pica, Antony J Lomax, Ralf Schneider, Barbara Bachtiary
BACKGROUND: Few data exist regarding the clinical outcome of patients with Ewing sarcoma (EWS) treated with pencil beam scanning proton therapy (PT). We report the outcome of children, adolescents and young adults (AYA) treated with PT at the Paul Scherrer Institute. MATERIALS: Thirty-eight patients (median age, 9.9 years) received a median dose of 54.9 Gy(RBE) (where RBE is relative biologic effectiveness). Size of the tumor ranged from 1.7 to 24 cm. Most common primary site was axial/pelvic (n = 27; 71%)...
December 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28587816/prognostic-value-of-the-preoperative-platelet-to-leukocyte-ratio-for-oncologic-outcomes-in-patients-undergoing-radical-cystectomy-for-bladder-cancer
#18
Gerald B Schulz, Tobias Grimm, Alexander Buchner, Friedrich Jokisch, Markus Grabbert, Birte-Swantje Schneevoigt, Alexander Kretschmer, Christian G Stief, Alexander Karl
BACKGROUND: Currently, stratification of patients with bladder cancer (BC) mainly relies on histopathologic and clinical staging. Furthermore, inflammation plays an important role in the pathogenesis of BC. With the preoperative platelet-to-leukocyte ratio (PLR), we introduce a novel prognostic marker based on routine hematologic values in patients undergoing radical cystectomy (RC). PATIENTS AND METHODS: In our cohort of 665 patients undergoing RC (2004-2015) for urothelial carcinoma of the bladder (UCB), we analyzed a variety of preoperative hematologic parameters...
May 10, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28578871/subclassification-of-pn3-staging-systems-for-penile-cancer-proposal-for-modification-of-the-current-tnm-classification
#19
Zhiyong Li, Shengjie Guo, Zhiming Wu, Hui Han, Zaishang Li, Yanjun Wang, Dong Chen, Jieping Chen, Chuangzhong Deng, Zike Qin, Zhuowei Liu, Yonghong Li, Kai Yao, Fanjian Zhou
OBJECTIVE: To validate the clinical and prognostic significance of our proposed pN3 subclassification in penile cancer. MATERIALS AND METHODS: A retrospective analysis of 509 patients with penile cancer undergoing partial, total penectomy or inguinal lymphadenectomy or pelvic lymphadenectomy at Sun Yat-sen University Cancer Center was reevaluated by pathologists. pN3 stage was subclassified into pN3a (extranodal extension of any inguinal lymph node [LN] metastasis only) and pN3b (pelvic LN metastasis)...
June 1, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28557042/enhancing-the-catalytic-activity-of-zeolitic-imidazolate-framework-8-derived-n-doped-carbon-with-incorporated-ceo2-nanoparticles-in-the-oxygen-reduction-reaction
#20
Yue Yu, Li Gao, Xianchun Liu, Yuanhong Wang, Shuangxi Xing
Incorporation of CeO2 nanoparticles into the cavity of zeolitic imidazolate framework-8 (ZIF-8) was followed by high-temperature pyrolysis to generate CeO2 @N-doped carbon materials. Introduction of the CeO2 nanoparticles greatly enhanced the catalytic activity of the ZIF-8-derived carbon materials in the oxygen reduction reaction (ORR) owing to the presence of Ce(3+) and oxygen vacancies with high content of chemisorbed oxygen in CeO2 and the well-maintained skeleton of the original ZIF-8 with uniform mesoporous structure...
May 29, 2017: Chemistry: a European Journal
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