keyword
MENU ▼
Read by QxMD icon Read
search

lead poisoning

keyword
https://www.readbyqxmd.com/read/28721171/response-to-an-unusual-outbreak-in-a-high-risk-situation
#1
Mahmood Muazu Dalhat, Olufunmilayo Ibitola Fawole, Patrick Mboya Nguku, Meeyoung Mattie Park, Casey Daniel Hall, Nasir Sani-Gwarzo
In 2010, a series of lead poisoning outbreaks linked to artisanal gold processing killed at least 400 young children in Zamfara State in northwestern Nigeria. There were several efforts to respond to the outbreaks as they occurred. Subsequent recurrence of lead poisoning outbreaks within Zamfara and beyond suggested that there were no efforts to mitigate the outbreaks as recommended for disaster management. This case study, to be completed within 3 hours, is suitable for senior level public health officials and those training for such positions...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28716507/a-novel-topoisomerase-2a-inhibitor-cryptotanshinone-suppresses-the-growth-of-pc3-cells-without-apparent-cytotoxicity
#2
Eun Ju Kim, Sun Young Kim, Sang-Man Kim, Minyoung Lee
DNA topoisomerase 2, which is ubiquitously expressed in eukaryotic cells, is an essential nuclear enzyme that promotes cell survival by regulating DNA topology and chromatid separation. This enzyme has been validated as a target for anticancer agent screening. It can be poisoned by common chemotherapeutics, such as etoposide and doxorubicin, which leads to the accumulation of cytotoxic enzyme-linked DNA double-stranded breaks. However, recent studies have suggested that the topoisomerase 2a isozyme is predominantly responsible for the carcinogenic side effects associated with etoposide and doxorubicin chemotherapy...
July 14, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28709509/poor-tap-water-quality-experiences-and-poor-sleep-quality-during-the-flint-michigan-municipal-water-crisis
#3
Daniel J Kruger, Gergana D Kodjebacheva, Suzanne Cupal
OBJECTIVES: After inadequate official response to community concerns over water quality following changes in Flint's municipal water supply, this study sought evidence for a relationship between water quality and community mental health. DESIGN: The Speak to Your Health Community Survey is a community-based participatory component of the health surveillance system in Genesee County, Michigan. This cross-sectional survey recruits participants from every residential Census Tract of the county and strives for demographic representativeness...
August 2017: Sleep Health
https://www.readbyqxmd.com/read/28695492/patterns-of-acute-poisoning-with-pesticides-in-the-paediatric-age-group
#4
Kavinda Chandimal Dayasiri, Shaluka F Jayamanne, Chamilka Y Jayasinghe
BACKGROUND: Pesticides are identified as one of the dangerous poisons globally in children and are associated with increased short- and long-term morbidity. Pesticide poisoning is the most common method of self-poisoning among adults in rural Sri Lanka, and the clinical management is associated with significant healthcare costs to the country. There is however little data published on acute pesticide poisoning among children in rural Sri Lanka. The current study aimed to comprehensively evaluate clinical profiles, harmful first aid measures, emergency clinical management, complications and outcomes related to acute pesticide poisoning among children in the rural community of Sri Lanka...
December 2017: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28692391/harnessing-syndromic-surveillance-emergency-department-data-to-monitor-health-impacts-during-the-2015-special-olympics-world-games
#5
Emily Kajita, Monica Z Luarca, Han Wu, Bessie Hwang, Laurene Mascola
INTRODUCTION: Mass gatherings that attract a large international presence may cause or amplify point-source outbreaks of emerging infectious disease. The Los Angeles County Department of Public Health customized its syndromic surveillance system to detect increased syndrome-specific utilization of emergency departments (EDs) and other medical encounters coincident to the 2015 Special Olympics World Games. MATERIALS AND METHODS: We queried live databases containing data on ED visits, California Poison Control System calls, and Los Angeles County coroner-investigated deaths for increases in daily counts from July 19 to August 6, 2015...
July 2017: Public Health Reports
https://www.readbyqxmd.com/read/28687772/improving-the-electrocatalytic-properties-of-pd-based-catalyst-for-direct-alcohol-fuel-cells-effect-of-solid-solution
#6
Cuilian Wen, Ying Wei, Dian Tang, Baisheng Sa, Teng Zhang, Changxin Chen
The tolerance of the electrode against the CO species absorbed upon the surface presents the biggest dilemma of the alcohol fuel cells. Here we report for the first time that the inclusion of (Zr, Ce)O2 solid solution as the supporting material can significantly improve the anti-CO-poisoning as well as the activity of Pd/C catalyst for ethylene glycol electro-oxidation in KOH medium. In particular, the physical origin of the improved electrocatalytic properties has been unraveled by first principle calculations...
July 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28682876/treatment-of-severe-fluoroacetamide-poisoning-in-patient-with-combined-multiple-organ-dysfunction-syndrome-by-evidence-based-integrated-chinese-and-western-medicines-a-case-report
#7
Wanxin Wen, Hongxia Gao, Nini Kang, Aili Lu, Caiwen Qian, Yuanqi Zhao
RATIONALE: Fluoroacetamide poisoning is the acute and severe disease of human, which leads to nervous, digestive, and cardiovascular system damage or even death in a short period of time. PATIENT CONCERNS: We report a case of a 65-year-old woman with loss of consciousness, nausea, and vomiting who was sent to the hospital by passers-by. DIAGNOSIS: She was diagnosed with severe fluoroacetamide poisoning with combined multiple organ dysfunction syndrome...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28680972/non-toxin-producing-bacillus-cereus-strains-belonging-to-the-b-%C3%A2-anthracis-clade-isolated-from-the-international-space-station
#8
Kasthuri Venkateswaran, Nitin K Singh, Aleksandra Checinska Sielaff, Robert K Pope, Nicholas H Bergman, Sandra P van Tongeren, Nisha B Patel, Paul A Lawson, Masataka Satomi, Charles H D Williamson, Jason W Sahl, Paul Keim, Duane Pierson, Jay Perry
In an ongoing Microbial Observatory investigation of the International Space Station (ISS), 11 Bacillus strains (2 from the Kibo Japanese experimental module, 4 from the U.S. segment, and 5 from the Russian module) were isolated and their whole genomes were sequenced. A comparative analysis of the 16S rRNA gene sequences of these isolates showed the highest similarity (>99%) to the Bacillus anthracis-B. cereus-B. thuringiensis group. The fatty acid composition, polar lipid profile, peptidoglycan type, and matrix-assisted laser desorption ionization-time of flight profiles were consistent with the B...
May 2017: MSystems
https://www.readbyqxmd.com/read/28678420/measurement-of-drug-stabilized-topoisomerase-ii-cleavage-complexes-by-flow-cytometry
#9
Marcelo de Campos Nebel, Micaela Palmitelli, Marcela González-Cid
The poisoning of Topoisomerase II (Top2) has been found to be useful as a therapeutic strategy for the treatment of several tumors. The mechanism of Top2 poisons involves a drug-mediated stabilization of a Top2-DNA complex, termed Top2 cleavage complex (Top2cc), which maintains a 5' end of DNA covalently bound to a tyrosine from Top2 through a phosphodiester group. Drug-stabilized Top2cc leads to Top2-linked-DNA breaks, which are believed to mediate their cytotoxicity. Several time-consuming or cell type-limiting assays have been used in the past to study drug-stabilized Top2cc...
July 5, 2017: Current Protocols in Cytometry
https://www.readbyqxmd.com/read/28677317/ayurvedic-plumbism
#10
Matthew Sadler, Sarah Bell
Ayurveda is a traditional medicine native to India but is used in many parts of the world as an alternative or adjunct to standard medicine. Preparation can involve incorporation of heavy metals, including lead. We report the case of a 64-year-old man presenting with malaise, abdominal pain, anaemia and very high lead levels. He was found to be taking ayurvedic medicines to help his diabetic control. Analysis of the ayurvedic medications showed several with very high lead content. Following treatment with an oral chelating agent, the patient's symptoms and blood abnormalities resolved...
July 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28671260/phenotypic-and-genotypic-characterization-of-staphylococcus-aureus-isolates-in-milk-from-flocks-diagnosed-with-subclinical-mastitis
#11
A R E O Xavier, A C Almeida, C N Souza, L M V Silva, A X A Ruas, D A Sanglard, A F M Júnior, A M E Oliveira, M A S Xavier
The Staphylococcus aureus is the most common isolated microorganism in ruminant animal species diagnostic with clinical or subclinical mastitis. Dairy herds with these diseases can transfer S. aureus into the milk supply, which can lead to food poisoning in humans. The objective of this study was to evaluate the profile of antimicrobial susceptibility, the presence of femA gene, the genetic relationships among isolates of S. aureus obtained from milk originating from flocks diagnosed with subclinical mastitis in nine rural properties in the northern of Minas Gerais State...
June 29, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28669384/differences-in-expression-of-genes-in-the-myd88-and-trif-signalling-pathways-and-methylation-of-tlr4-and-trif-in-tibetan-chickens-and-daheng-s03-chickens-infected-with-salmonella-enterica-serovar-enteritidis
#12
Xiaocheng Li, Peng Zhang, Xiaosong Jiang, Huarui Du, Chaowu Yang, Zengrong Zhang, Shuai Men, Zhikun Zhang, Wei Jiang, Hongning Wang
Salmonella enterica serovar (S. enteritidis) is a pathogenic bacterium that can cause symptoms of food poisoning, leading to death of poultry, resulting in serious economic losses. The MyD88 and TRIF signalling pathways play important roles in activating innate and adaptive immunity in chickens infected with S. enteritidis. The objective of the present study was to characterize in vivo mRNA expressions, protein levels and methylation levels of genes in the above two pathways in both Tibetan chickens and DaHeng S03 chickens infected with S...
July 2017: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/28666216/assessment-of-28-trace-elements-and-17-amino-acid-levels-in-muscular-tissues-of-broiler-chicken-gallus-gallus-suffering-from-arsenic-trioxide
#13
Si-Wen Li, Ying He, Hong-Jing Zhao, Yu Wang, Juan-Juan Liu, Yi-Zhi Shao, Jing-Lun Li, Xiao Sun, Li-Na Zhang, Ming-Wei Xing
The contents of 28 trace elements, 17 amino acid were evaluated in muscular tissues (wings, crureus and pectoralis) of chickens in response to arsenic trioxide (As2O3). A total of 200 one-day-old male Hy-line chickens were fed either a commercial diet (C-group) or an As2O3 supplement diet containing 7.5mg/kg (L-group), 15mg/kg (M-group) or 30mg/kg (H-group) As2O3 for 90 days. The elements content was analyzed by inductively coupled plasma mass spectrometry (ICP-MS). Under As2O3 exposure, the concentration of As were elevated 8...
June 27, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28659131/childhood-pesticide-poisoning-in-zhejiang-china-a-retrospective-analysis-from-2006-to-2015
#14
Aziguli Yimaer, Guangdi Chen, Meibian Zhang, Lifang Zhou, Xinglin Fang, Wei Jiang
BACKGROUND: Pesticide poisoning in children has been a serious public health issue around the world, especially in the developing countries where agriculture is still one of the largest economic sectors. The purpose of this study was to analyze epidemiological characteristics of acute pesticide poisoning in children from Zhejiang province, China. METHODS: The pesticide poisoning cases for children were retrieved from Occupational Disease Surveillance and Reporting System, Zhejiang Provincial Center for Disease Control and Prevention, China...
June 28, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28655298/assessment-of-staphylococcus-aureus-along-milk-value-chain-and-its-public-health-importance-in-sebeta-central-oromia-ethiopia
#15
Yodit Ayele, Fanta Desissa Gutema, Bedaso Mamo Edao, Robel Girma, Takele Beyene Tufa, Tariku Jibat Beyene, Fanos Tadesse, Mesula Geloye, Ashenafi Feyisa Beyi
BACKGROUND: Staphylococcus aureus is one of the leading causes of gastroenteritis acquired from contaminated foods such as milk and milk products. However, such information is limited in Ethiopia. A cross-sectional study was conducted to assess the contamination of milk with S. aureus and knowledge, attitudes and practices (KAP) of actors along the milk value chain in Sebeta, Central Oromia, Ethiopia. A total of 291 samples collected from dairy farms, milk collection centers (MCCs) and processing plant were examined using standard microbiological techniques...
June 27, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28652152/improving-the-integrity-of-natural-biopolymer-films-used-in-food-packaging-by-crosslinking-approach-a-review
#16
REVIEW
Farhad Garavand, Milad Rouhi, Seyed Hadi Razavi, Ilaria Cacciotti, Reza Mohammadi
Currently used approaches for biopolymer modification are either expensive, poisonous or do not lead into the well-desired characteristics to the final film materials. Development of crosslinking procedure is an innovative strategy to improve mechanical, physical and thermal properties of biopolymer films. This review provides a brief description of film-forming biopolymers (e.g. chitosan, whey protein, alginate and starch) followed by a detailed introduction to definition and classification of various crosslinkers, the effect of crosslinking on emerging attributes of biopolymer films including physical, mechanical and thermal properties, identification of crosslinking occurrence, and cytotoxicity status of commonly used crosslinkers in the field of food and food-related packaging materials...
June 23, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28648373/economic-assessment-of-wild-bird-mortality-induced-by-the-use-of-lead-gunshot-in-european-wetlands
#17
Alessandro Andreotti, Vittorio Guberti, Riccardo Nardelli, Simone Pirrello, Lorenzo Serra, Stefano Volponi, Rhys E Green
In European wetlands, at least 40 bird species are exposed to the risk of lead poisoning caused by ingestion of spent lead gunshot. Adopting a methodology developed in North America, we estimated that about 700,000 individuals of 16 waterbird species die annually in the European Union (EU) (6.1% of the wintering population) and one million in whole Europe (7.0%) due to acute effects of lead poisoning. Furthermore, threefold more birds suffer sub-lethal effects. We assessed the economic loss due to this lead-induced mortality of these 16 species by calculating the costs of replacing lethally poisoned wild birds by releasing captive-bred ones...
June 22, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28644767/blood-lead-levels-and-risk-factors-for-lead-exposure-among-pregnant-women-in-western-french-guiana-the-role-of-manioc-consumption
#18
Diane Rimbaud, Marion Restrepo, Anne Louison, Rachida Boukhari, Vanessa Ardillon, Gabriel Carles, Véronique Lambert, Anne Jolivet
Concerns regarding lead (Pb) poisoning in French Guiana first arose in 2011 following the discovery of excessively high levels of the metal amongst children in a small neighborhood without any apparent source of Pb. Since 2012, blood lead level (BLL) measurement has been proposed for all pregnant women in western French Guiana. The aim of this study was to determine BLL in pregnant women in this region and identify factors associated with elevated BLL. An observational study of a consecutive sample of women who delivered in the maternity ward of the hospital was conducted...
2017: Journal of Toxicology and Environmental Health. Part A
https://www.readbyqxmd.com/read/28644742/new-legal-requirements-for-submission-of-product-information-to-poisons-centres-in-eu-member-states
#19
Ronald de Groot, Pieter Brekelmans, Herbert Desel, Irma de Vries
In the past eight years, the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT) has been intensively involved in a European Commission led process to develop EU legislation on the information of hazardous products that companies have to notify to EU Poisons Centres (or equivalent "appointed bodies"). As a result of this process, the Commission adopted Regulation (EU) No 2017/542, amending the CLP Regulation by adding an Annex on harmonised product submission requirements. Harmonised mixture information requirements: Detailed and consistent information on the composition of the hazardous product will become available to EU Poisons Centres (PC)...
June 23, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28643849/prevalence-of-exposure-of-heavy-metals-and-their-impact-on-health-consequences
#20
Kanwal Rehman, Fiza Fatima, Iqra Waheed, Muhammad Sajid Hamid Akash
Even in the current era of growing technology, the concentration of heavy metals present in drinking water is still not within the recommended limits as set by the regulatory authorities in different countries of the world. Drinking water contaminated with heavy metals namely; arsenic, cadmium, nickel, chromium, mercury, chromium, zinc and lead is becoming a major health concern for public and health care professionals. Occupational exposure to heavy metals is known to occur by the utilization of these metals in various industrial processes and/or contents including color pigments and alloys...
June 23, 2017: Journal of Cellular Biochemistry
keyword
keyword
87775
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"