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Fresh embryo transfer

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https://www.readbyqxmd.com/read/29675483/fresh-versus-frozen-embryo-transfer-after-gonadotropin-releasing-hormone-agonist-trigger-in-gonadotropin-releasing-hormone-antagonist-cycles-among-high-responder-women-a-randomized-multi-center-study
#1
Abbas Aflatoonian, Mahnaz Mansoori-Torshizi, Maryam Farid Mojtahedi, Behrouz Aflatoonian, Mohammaad Ali Khalili, Mohammad Hossein Amir-Arjmand, Mehrdad Soleimani, Nastaran Aflatoonian, Homa Oskouian, Nasim Tabibnejad, Peter Humaidan
Background: The use of embryo cryopreservation excludes the possible detrimental effects of ovarian stimulation on the endometrium, and higher reproductive outcomes following this policy have been reported. Moreover, gonadotropin-releasing hormone agonist trigger in gonadotropin-releasing hormone (GnRH) antagonist cycles as a substitute for standard human chorionic gonadotropin trigger, minimizes the risk of ovarian hyperstimulation syndrome (OHSS) in fresh as well as frozen embryo transfer cycles (FET)...
January 2018: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/29673730/early-oocyte-denudation-does-not-compromise-icsi-cycle-outcome-a-large-retrospective-cohort-study
#2
Osama Naji, Natalie Moska, Yaser Dajani, Awatuf El-Shirif, Hassan El-Ashkar, Mohamed Hosni, Mohamed Khalil, Yacoub Khalaf, Virginia Bolton, Tarek El-Toukhy
This retrospective cohort study of 2051 consecutive fresh non-donor intracytoplasmic sperm injection (ICSI) cycles investigated whether time from oocyte retrieval to denudation, precisely measured and recorded by an operator-independent automated radiofrequency-based system, affected cycle outcome. ICSI cycles were divided into two groups: group I (denudation within <2 h of oocyte retrieval, n = 1118) and group II (denudation 2-5 h after oocyte retrieval, n = 933). Univariate analysis by two-sample t-test or Mann-Whitney test was used, as appropriate...
April 4, 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29662822/effects-of-three-area-laser-assisted-zona-thinning-in-8-cell-human-embryos-on-pregnancy-outcomes-in-vitro-fertilization
#3
Ju-Eun Jeong, Bo-Sun Joo, Chang-Woon Kim, Hwi-Gon Kim, Jong-Kil Joo, Kyu-Sup Lee
Objective: This study conducted a preliminary examination of the effects of three-area laser-assisted zona thinning (LAZT) during the cleavage stage of embryo development on the hatching process in human in vitro fertilization-embryo transfer (IVF-ET) with subjects of advanced female age or frozen-thawed (FT) embryos. Methods: Eight-cell stage embryos were treated with LAZT in three areas of the zona pellucida at 120° intervals. The control group was embryos without LAZT...
March 2018: Clinical and Experimental Reproductive Medicine
https://www.readbyqxmd.com/read/29662715/the-effect-of-the-pooling-method-on-the-live-birth-rate-in-poor-ovarian-responders-according-to-the-bologna-criteria
#4
Serdar Çelik, Niyazi Emre Turgut, Dilek Cengiz Çelik, Kübra Boynukalın, Remzi Abalı, Sevim Purisa, Erbil Yağmur, Mustafa Bahçeci
Objective: Pooling is an alternative method to achieve in vitro fertilization outcomes. This study was to investigate the effect of pooling method on pregnancy outcomes in poor responder patients according to Bologna criteria. Materials and Methods: Two hundred-fifty five poor responder patients were enrolled in this study. Pooling embryo transfer (ET) group had 110 and fresh ET group had 145 patients. Results: Although, age was similar between both treatment groups (p=0...
March 2018: Turkish Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29661236/clinical-analysis-of-50-patients-with-heterotopic-pregnancy-after-ovulation-induction-or-embryo-transfer
#5
Zaigui Wu, Xinmei Zhang, Ping Xu, Xiufeng Huang
OBJECTIVES: The purpose of this study was to evaluate the clinical characteristics, prenatal diagnosis, and management of patients with heterotopic pregnancy after ovulation induction or embryo transfer. METHODS: This was a retrospective study of fifty cases with heterotopic pregnancy, in which the fertilization way, type and number of embryo transferred, gestational age, clinical presentation and outcome of intrauterine, ultrasound presentation and site of ectopic pregnancy, bilateral fallopian tube and treatment were evaluated...
April 16, 2018: European Journal of Medical Research
https://www.readbyqxmd.com/read/29659826/association-between-ambient-air-pollution-and-pregnancy-rate-in-women-who-underwent-ivf
#6
S A Choe, Y B Jun, W S Lee, T K Yoon, S Y Kim
STUDY QUESTION: Are the concentrations of five criteria air pollutants associated with probabilities of biochemical pregnancy loss and intrauterine pregnancy in women? SUMMARY ANSWER: Increased concentrations of ambient particulate matter (PM10), nitrogen dioxide (NO2), carbon monoxide (CO) during controlled ovarian stimulation (COS) and after embryo transfer were associated with a decreased probability of intrauterine pregnancy. WHAT IS KNOWN ALREADY: Exposure to high ambient air pollution was suggested to be associated with low fertility and high early pregnancy loss in women...
April 5, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29651380/a-combined-pathway-of-organogenesis-and-somatic-embryogenesis-for-an-efficient-large-scale-propagation-in-date-palm-phoenix-dactylifera-l-cv-mejhoul
#7
Mouaad Amine Mazri, Reda Meziani, Ilham Belkoura, Boutaïna Mokhless, Souad Nour
An efficient regeneration system via a combined pathway of organogenesis and somatic embryogenesis was developed for date palm ( Phoenix dactylifera L.) cv. Mejhoul. Adventitious buds were obtained from shoot-tip explants with a frequency of 53.3% after 9 months of culture: 6 months on half-strength Murashige and Skoog (MS/2) medium containing 14.2 µM indole-3-acetic acid (IAA), 13.4 µM 1-naphthaleneacetic acid (NAA) and 0.5 µM 6-(dimethylallylamino) purine (2iP), and 3 months on MS/2 medium supplemented with 1...
April 2018: 3 Biotech
https://www.readbyqxmd.com/read/29625802/cryosurvival-of-rabbit-embryos-obtained-after-superovulation-with-corifollitropin-alfa-with-or-without-lh
#8
José Salvador Vicente, María Pilar Viudes-de-Castro, José Isaí Cedano-Castro, Francisco Marco-Jiménez
The efficiency of an embryo bank depends on provision of optimal conditions for recovery, cryopreservation and transfer to a breed or strain. In this sense, increasing the number of embryos available using superovulation should improve the cryobank efficiency. However, vagueness of response to conventional protocols to control or increase ovarian response and the quality of oocytes and embryos and their cryotolerance remain a challenge. The aim of our study was to evaluate the effect of corifollitropin alpha (CTP) and a recombinant human FSH (rhFSH), alone or supplemented with rhLH, on embryo cryosurvival by in vitro development and OCT4 and NANOG mRNA abundance at blastocyst stage and offspring rate...
March 31, 2018: Animal Reproduction Science
https://www.readbyqxmd.com/read/29605408/cumulus-oophorus-complexes-favor-physiologic-selection-of-spermatozoa-for-intracytoplasmic-sperm-injection
#9
Caizhu Wang, Guixue Feng, Jinhui Shu, Hong Zhou, Bo Zhang, Huanhua Chen, Ruoyun Lin, Xianyou Gan, Zhulian Wu, Tinglv Wei
OBJECTIVE: To investigate the effectiveness of cumulus oophorus complexes (COCs) in the physiologic selection of spermatozoa for intracytoplasmic sperm injection (ICSI). DESIGN: A prospective sibling oocytes study. SETTING: Center of reproductive medicine. PATIENT(S): Couples undergoing ICSI during 2016, females aged ≤38 years, and at least six metaphase II (MII) oocytes retrieved. Sixty patients were included in the study...
March 28, 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29597124/plasma-igf-i-insl3-testosterone-inhibin-concentrations-and-scrotal-circumferences-surrounding-puberty-in-japanese-black-beef-bulls-with-normal-and-abnormal-semen
#10
W W P N Weerakoon, M Sakase, N Kawate, M A Hannan, N Kohama, H Tamada
The relationships between semen abnormalities and peripheral concentrations of testicular and metabolic hormones in beef bulls are unclear. Here we compared plasma insulin-like growth factor I (IGF-I), insulin-like peptide 3 (INSL3), testosterone, inhibin concentrations, and scrotal circumferences surrounding puberty in Japanese Black beef bulls (n = 66) with normal or abnormal semen. We collected blood samples and measured scrotal circumferences monthly from 4 to 24 months of age. Semen was collected weekly from 12 months until at least 18 months of age...
March 15, 2018: Theriogenology
https://www.readbyqxmd.com/read/29589293/the-effect-of-day-2-versus-day-3-embryo-transfer-on-early-pregnancy-outcomes-in-women-with-a-low-yield-of-fertilized-oocytes
#11
C R Sacha, I Dimitriadis, G Christou, I Souter, C L Bormann
PURPOSE: To evaluate the differences in implantation and pregnancy rates when embryo transfer occurs on D2 versus D3 in women with a low yield of fertilized oocytes. METHODS: A total of 156 IVF/ICSI cycles from 141 women at an academic fertility center were analyzed in a retrospective fashion. Women with a low number of fertilized oocytes (≤ 2 two pronuclei (2PN) stage zygotes) who had their fresh embryo transfer on D2 or D3 were included in the study. Positive pregnancy test per IVF cycle (PPT), clinical pregnancy rate (CPR), spontaneous abortion rate (SABR), and implantation rate (IMPR) were the main outcome measures assessed...
March 27, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29576001/impact-of-metformin-on-ivf-outcomes-in-overweight-and-obese-women-with-polycystic-ovary-syndrome-a-randomized-double-blind-controlled-trial
#12
Osama S Abdalmageed, Tarek A Farghaly, Ahmed A Abdelaleem, Ahmed E Abdelmagied, Mohammed K Ali, Ahmed M Abbas
OBJECTIVES: To evaluate the impact of metformin on in vitro fertilization (IVF) outcomes in overweight and obese women with polycystic ovary syndrome (PCOS). METHODS: This was a randomized double-blind placebo-controlled study ( ClinicalTrials.gov : NCT 02910817) carried out in a University IVF Center. The study included 102 overweight and obese women (body mass index [BMI] >24 kg/m2 ) with PCOS who underwent their first fresh autologous IVF-embryo transfer cycle and agreed to participate in the study...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29567383/eventual-re-vitrification-or-storage-in-liquid-nitrogen-vapor-does-not-jeopardize-the-practical-handling-and-transport-of-vitrified-pig-embryos
#13
Alicia Nohalez, Cristina A Martinez, Inmaculada Parrilla, Carolina Maside, Jordi Roca, María A Gil, Heriberto Rodriguez-Martinez, Emilio A Martinez, Cristina Cuello
This study aimed (1) to evaluate the in vitro post-warming survival of porcine embryos after re-vitrification and (2) to assess the efficacy of transport of embryos in dry shipper (DS) in maintaining the viability and quality of vitrified embryos for a 3-day period. Embryos at the compacted or cavitating morula (CCM) and unhatched blastocyst (UBL) stages were surgically obtained from weaned, crossbred sows. In the first experiment, more than 85% of the embryos survived an initial vitrification and warming and achieved comparable survival rates to those of their fresh counterparts...
March 8, 2018: Theriogenology
https://www.readbyqxmd.com/read/29551013/the-interval-transfer-of-a-frozen-thawed-embryo-is-more-successful-than-a-fresh-embryo-transfer-for-women-undergoing-ivf-with-recurrent-implantation-failure-after-cleavage-stage-embryo-biopsy
#14
Jennifer C Pontré, John P Ryan, Andy Tan, Roger J Hart
BACKGROUND: Recurrent implantation failure (RIF) is repeated unsuccessful embryo transfers (ETs). AIMS: To identify predictive embryonic markers of implantation in RIF, following pre-implantation genetic screening (PGS) of cleavage stage embryos, after accounting for male and female factors. MATERIALS AND METHODS: Retrospective analysis of RIF patients undergoing PGS after correction of modifiable causes. RESULTS: Eighty-four patients underwent 140 in vitro ferilisation cycles...
March 18, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29546361/single-embryo-transfer-by-day-3-time-lapse-selection-versus-day-5-conventional-morphological-selection-a-randomized-open-label-non-inferiority-trial
#15
Lanlin Yang, Sufen Cai, Shuoping Zhang, Xiangyi Kong, Yifan Gu, Changfu Lu, Jing Dai, Fei Gong, Guangxiu Lu, Ge Lin
STUDY QUESTION: Does single cleavage-stage (Day 3) embryo transfer using a time-lapse (TL) hierarchical classification model achieve comparable ongoing pregnancy rates (OPR) to single blastocyst (Day 5) transfer by conventional morphological (CM) selection? SUMMARY ANSWER: Day 3 single embryo transfer (SET) with a hierarchical classification model had a significantly lower OPR compared with Day 5 SET with CM selection. WHAT IS KNOWN ALREADY: Cleavage-stage SET is an alternative to blastocyst SET...
March 13, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29545772/a-proof-of-concept-clinical-trial-of-a-single-luteal-use-of-long-acting-gonadotropin-releasing-hormone-antagonist-degarelix-in-controlled-ovarian-stimulation-for-in-vitro-fertilization-long-antagonist-protocol
#16
Evangelos G Papanikolaou, Hakan Yarali, Evi Timotheou, Michael Grynberg, Odysseas Zafeiratis, Herman Tournaye, Robert Najdecki
Introduction: A drawback of gonadotropin-releasing hormone (GnRH) antagonist protocols in in vitro fertilization (IVF) is that they have limited flexibility in cycle programming. This proof of concept study explored the efficacy of a single-dose, long-acting GnRH antagonist IVF protocol. Trial registration number is NCT03240159, retrospectively registered on March 08, 2017. Materials and methods: The efficacy of a single-dose long-acting antagonist, degarelix, was explored initially in healthy donors and subsequently in infertile patients...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29534178/live-birth-rates-in-the-first-complete-ivf-cycle-among-20-687-women-using-a-freeze-all-strategy
#17
Qianqian Zhu, Qiuju Chen, Li Wang, Xuefeng Lu, Qifeng Lyu, Yun Wang, Yanping Kuang
STUDY QUESTION: What is the chance of having a child following one complete IVF cycle for patients using a freeze-all strategy? SUMMARY ANSWER: The chance of having a child after the first complete IVF cycle was 50.74% with the freeze-all strategy. WHAT IS KNOWN ALREADY: Several studies have reported on live birth rates (LBRs) based on only the fresh embryo transfer cycle or fresh and frozen-thawed embryo transfer cycles. However, the LBR using a freeze-all strategy in IVF is unknown...
March 9, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29534148/preterm-birth-and-small-for-gestational-age-in-singleton-in-vitro-fertilization-births-using-donor-oocytes
#18
Sheree L Boulet, Jennifer F Kawwass, Sara Crawford, Michael J Davies, Dmitry M Kissin
We used 2006-2015 US National Assisted Reproductive Technology Surveillance System data to compare preterm birth and fetal growth for livebo n singletons (24-42 week gestation) following donor versus autologous oocyte in vitro fertilization (IVF). Using binary and multinomial logistic regressi n, we computed adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for associations between use of donor oocytes and preterm delivery, small-f r-gestational-age (SGA), and large-for-gestational age (LGA), stratified by fresh and thawed embryo status and accounting for maternal characteristics and year of birth...
March 9, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29530836/the-effect-of-intramural-fibroids-without-an-intra-cavity-component-on-in-vitro-fertilization-outcomes-in-single-fresh-blastocyst-transfer-cycles
#19
Sadikah Behbehani, Stefano Polesello, Joseph Hasson, Justin Silver, Weon-Young Son, Michael Dahan
OBJECTIVE: Asses clinical pregnancy rates and live birth rates in the presence of non-cavity deforming intramural fibroids in single fresh blastocyst transfer cycles DESIGN CLASSIFICATION: Canadian Task Force classification II-2 SETTING SETTING: Academic fertility center. PATIENT(S): 929 fresh single blastocyst transfer cycles were included; 94 with only non cavity distorting intramural fibroids and 764 without fibroids. Cleavage embryo transfers were excluded to reduce bias based on embryo quality INTERVENTION(S): none MAIN OUTCOME MEASURE(S): Live birth rate (LBR) and clinical pregnancy rate (CPR) RESULT(S): There were no differences noted in gravity, parity, or body mass index in patients with and without fibroids...
March 9, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29502243/thawed-embryo-transfer-and-ectopic-pregnancy-a-meta-analysis
#20
REVIEW
Weijie Xing, Jianping Ou, Liuhong Cai
PURPOSE: To examine whether thawed embryo transfers can reduce the rate of EP. METHODS: The PubMed, EMBASE, Cochrane Library databases and two randomized controlled trials registration centers were thoroughly searched until March 2017. The clinical outcomes of IVF/ICSI cycles were compared between thawed and fresh embryo transfer. RESULTS: Twenty-one articles were included in this meta-analysis. There were 801,464 pregnancies totally (thawed-ET: n = 158,967, fresh-ET: n = 642,497)...
March 3, 2018: Archives of Gynecology and Obstetrics
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