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https://www.readbyqxmd.com/read/29149789/involving-institutionalized-people-with-dementia-in-their-care-planning-meetings-impact-on-their-quality-of-life-measured-by-a-proxy-method
#1
Feliciano Villar, Montserrat Celdrán, Josep Vila-Miravent, Elena Fernández
The objective of the study was to assess the impact of an intervention in which people with dementia attended meetings to discuss their individual care plans on their quality of life. Fifty-two older people ( M = 86.7 years, SD = 7.3) diagnosed with moderate-to-severe dementia living in four nursing homes in Spain participated in the study. The intervention was implemented with 27 residents at two of the nursing homes; the other 25 cases at the other two homes acted as controls. A proxy measure of quality of life was used...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/29149785/association-study-of-hla-dqb1-0602-allele-in-iranian-patients-with-narcolepsy
#2
Demeke Geremew, Ania Rahimi-Golkhandan, Khosro Sadeghniiat-Haghighi, Yadollah Shakiba, Ahmad Khajeh-Mehrizi, Bita Ansaripour, Maryam Izad
Narcolepsy is a rare, disabling disorder characterized by excessive daytime sleepiness, cataplexy, hypnagogic hallucinations and sleep paralysis. Several studies demonstrated its association with HLA-DQB1*0602 in various ethnic groups. Our study aimed to determine the prevalence of HLA-DQB1*0602 allele in Iranian patients with narcolepsy and assess its predictive parameters for diagnosing narcolepsy. In addition, car accidents and job problems were assessed among narcoleptic patients. We studied 44 narcoleptic patients, 30 patients with other types of excessive daytime sleepiness (EDS)  and 50 healthy age and sex matched individuals in this case-control study...
October 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/29149777/investigating-the-association-of-adam33-single-nucleotide-polymorphisms-snps-with-susceptibility-to-allergic-asthma-in-azerbaijan-population-of-iran-a-case-control-study
#3
Ilghar Zeinaly, Mahnaz Sadeghi-Shabestrai, Zohreh Babaloo, Alireza Razavi, Mohammad Sajay-Asbaghi, Saeed Sadigh-Eteghad, Tohid Kazemi
Asthma, affecting a growing number of populations, is a clinical condition with complex cellular and genetic factors. Single nucleotide polymorphisms (SNPs) in gene coding for molecules, which play major roles in the immunopathogenesis of asthma have been considered recently as genetic predisposing factors this disease. Possible association between two SNPs in a disintegrin and metalloprotease 33 (ADAM33), which participates in airway remodeling, and susceptibility to asthma was studied in this study. 190 patients with asthma and 180 healthy controls were enrolled in this case-control study...
October 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/29149750/friends-or-foes-monetized-life-cycle-assessment-and-cost-benefit-analysis-of-the-site-remediation-of-a-former-gas-plant
#4
Lies Huysegoms, Sandra Rousseau, Valérie Cappuyns
Site contamination is a global concern because of the potential risks for human health and ecosystem quality. Every contaminated site has its own specific characteristics and the increased availability and efficiency of remediation techniques makes the choice of remediation alternative increasingly complicated. In this paper an attributional Life Cycle Assessment (LCA) of the secondary environmental impacts of a site remediation is performed and its results are monetized using two different monetization techniques, namely Stepwise 2006 and Ecovalue 08...
November 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29149739/removal-of-tio2-nanoparticles-from-water-by-low-pressure-pilot-plant-filtration
#5
Josune Olabarrieta, Oihane Monzón, Yolanda Belaustegui, Jon-Iñaki Alvarez, Saioa Zorita
Rising use of nanoparticles in manufacturing as well as in commercial products bring issues related to environmental release and human exposure. A large amount of TiO2 nanoparticles will eventually reach wastewater treatment plants. Low pressure membrane filtration has been suggested as a feasible treatment of water streams. This study investigated first at laboratory scale the influence of: i) membrane material, ii) pore size and iii) water chemistry on nTiO2 removal. TiO2 retention was governed by the cake layer formation mechanism and significant retention of nanoparticles was observed even for filters having considerably larger pores than nTiO2...
November 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29149718/coronary-risk-assessment-at-x-ray-dose-equivalent-ungated-chest-ct-results-of-a-multi-reader-study
#6
Michael Messerli, Lukas Hechelhammer, Sebastian Leschka, René Warschkow, Simon Wildermuth, Ralf W Bauer
OBJECTIVES: To determine the value of ultra-low dose chest CT with tin filtration for ordinal coronary artery calcium (CAC) risk scoring. METHODS: 50 patients were prospectively included and underwent clinical standard dose chest CT (1.8±0.7mSv) and ultra-low dose CT (0.13±0.01mSv). Four radiologists estimated presence and extent of CAC. RESULTS: Weighted kappa values for CAC were 0.76-0.97 in standard dose and 0.75-0.95 in ultra-low dose CT (p<0...
October 25, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29149708/photodegradation-of-novel-oral-anticoagulants-under-sunlight-irradiation-in-aqueous-matrices
#7
Montaha Yassine, Laura Fuster, Marie-Hélène Dévier, Emmanuel Geneste, Patrick Pardon, Axelle Grélard, Erick Dufourc, Mohamad Al Iskandarani, Selim Aït-Aïssa, Jeanne Garric, Hélène Budzinski, Patrick Mazellier, Aurélien S Trivella
Kinetics of photodegradation of novel oral anticoagulants dabigatran, rivaroxaban, and apixaban were studied under simulated solar light irradiation in purified, mineral, and river waters. Dabigatran and rivaroxaban underwent direct photolysis with polychromatic quantum yields of 2.2 × 10(-4) and 4.4 × 10(-2), respectively. The direct photodegradation of apixaban was not observed after 19 h of irradiation. Kinetics of degradation of rivaroxaban was not impacted by the nature of the aqueous matrix while photosensitization from nitrate ions was observed for dabigatran and apixaban dissolved in a mineral water...
November 9, 2017: Chemosphere
https://www.readbyqxmd.com/read/29149646/dependence-of-growth-inhibiting-action-of-increased-planting-density-on-capacity-of-lettuce-plants-to-synthesize-aba
#8
Lidiya B Vysotskaya, Tatyana N Arkhipova, Guzel R Kudoyarova, Stanislav Yu Veselov
Inhibition of lettuce plant growth under increased planting density was accompanied by accumulation of abscisic acid (ABA) in the shoots of competing plants. To check causal relationship between these responses we studied the effect of decreased synthesis of ABA on growth indexes and hormonal balance of lettuce plants under elevated density of their planting (one (single) or three (competing) plants per pot). Herbicide fluridone was used to inhibit ABA synthesis. Preliminary experiments with single plants showed that presence of fluridone in the soil solution at rather low concentration (0...
November 11, 2017: Journal of Plant Physiology
https://www.readbyqxmd.com/read/29149641/site-closure-management-strategies-and-the-responsiveness-of-conservation-outcomes-in-recreational-fishing
#9
Lei Gao, Atakelty Hailu
We develop and use an empirically based model, which integrates fishing behaviour and a coral reef system, to evaluate outcomes from site closure strategies to manage the effects of recreational fishing. The model is designed to estimate management effects in complex settings with two-way feedback effects (between fishing and ecosystem dynamics) as well as spillover effects where the closure of a site (or sites) leads to the redistribution of fishing effort. An iconic coral reef system is used as a case study...
November 14, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/29149621/the-risk-factors-related-to-bruxism-in-children-a-systematic-review-and-meta-analysis
#10
REVIEW
Huaqi Guo, Tongxia Wang, Xiaohong Niu, Hui Wang, Weihan Yang, Jie Qiu, Lan Yang
OBJECTIVE: This systematic review was performed to determine the risk factors related to bruxism in children. DESIGN: This systematic review was conducted with reporting in agreement to the PRISMA statement and according to guidelines from the Cochrane Handbook for Systematic Reviews of Interventions. We conducted a systematic search of seven online databases, with the last search updated on 1st October 2016. The seven databases were Pubmed, Embase, Cochrane Library database, Web of Science, CNKI, CBM, and WF...
November 11, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29149549/workflow-for-target-oriented-parametrization-of-an-enhanced-mechanistic-cell-culture-model
#11
Sophia Ulonska, Paul Kroll, Jens Fricke, Christoph Clemens, Raphael Voges, Markus Michael Müller, Christoph Herwig
The goal of this study was to develop a macroscopic mechanistic model describing growth and production within fed-batch cultivations of CHO cells. The model should be used for process characterization as well as for process monitoring including real-time parameter adaptations. The model proved to be able to describe a data-set of 40 processes differing in clones, scales and process conditions with a normalized root mean square error of approximately 10%. However, due to limited parameter identifiability and limited knowledge about physiologically meaningful parameter values, a broad range of parameters could describe the data with similar quality...
November 17, 2017: Biotechnology Journal
https://www.readbyqxmd.com/read/29149507/registered-nurse-and-midwife-experiences-of-using-videoconferencing-in-practice-a-systematic-review-of-qualitative-studies
#12
REVIEW
Robyn A Penny, Natalie K Bradford, Danette Langbecker
AIM: To synthesise evidence of registered nurses' and midwives' experiences with videoconferencing and identify perceptions of the appropriateness, meaningfulness and feasibility of this technology in professional and clinical practice. BACKGROUND: Videoconferencing is a form of telehealth that can facilitate access to high quality care to improve health outcomes for patients and enable clinicians working in isolation to access education, clinical supervision, peer support and case review...
November 17, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29149504/mybl1-rearrangements-and-myb-amplification-in-breast-adenoid-cystic-carcinomas-lacking-the-myb-nfib-fusion-gene
#13
Jisun Kim, Felipe C Geyer, Luciano G Martelotto, Charlotte K Y Ng, Raymond S Lim, Pier Selenica, Anqi Li, Fresia Pareja, Nicola Fusco, Marcia Edelweiss, Rahul Kumar, Rodrigo Gularte-Merida, Andre N Forbes, Ekta Khurana, Odette Mariani, Sunil Badve, Anne Vincent-Salomon, Larry Norton, Jorge S Reis-Filho, Britta Weigelt
Breast adenoid cystic carcinoma (AdCC), a rare type of triple-negative breast cancer (TNBC), has been shown to be driven by MYB pathway activation, most often underpinned by the MYB-NFIB fusion gene. Alternative genetic mechanisms, such as MYBL1 rearrangements, have been reported in MYB-NFIB-negative salivary gland AdCCs. Here we report on the molecular characterization by massively parallel sequencing of four breast AdCCs lacking the MYB-NFIB fusion gene. In two cases, we identified MYBL1 rearrangements (MYBL1-ACTN1 and MYBL1-NFIB), which were associated with MYBL1 overexpression...
November 17, 2017: Journal of Pathology
https://www.readbyqxmd.com/read/29149498/association-between-a-single-nucleotide-polymorphism-in-the-grem1-gene-and-nonsyndromic-orofacial-cleft-in-the-chinese-population
#14
Xiaotong Wang, Hongquan Song, Xiaohui Jiao, Yanru Hao, Wei Zhang, Yuwei Gao, Yong Li, Na Mi, Jiaqun Yan
BACKGROUND: Nonsyndromic orofacial cleft (NSOC) is a common craniofacial deformity among newborns. The GREM1 gene is correlated with orofacial development. The aim of our study was to investigate the association between a single-nucleotide polymorphism in the GREM1 gene and this malformation in the Chinese population. METHODS: The SNaPshot mini sequencing technique was used to genotype the locus rs1258763 of the GREM1 gene in 331 patients with NSOC and 271 individuals in a control group...
November 17, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/29149469/cuffed-versus-uncuffed-endotracheal-tubes-for-general-anaesthesia-in-children-aged-eight-years-and-under
#15
REVIEW
Flavia A De Orange, Rebeca Gac Andrade, Andrea Lemos, Paulo Sgn Borges, José N Figueiroa, Pete G Kovatsis
BACKGROUND: Since the introduction of endotracheal intubation in paediatrics, uncuffed endotracheal tubes (ETTs) have been the standard of care for children under eight years old, based on the presumption that complications, particularly postoperative stridor, are higher with cuffed ETTs. The major disadvantages of uncuffed ETTs cited for this shift in procedure include the difficulty in achieving tidal volumes due to leakage around an uncuffed ETT. To seal the airway adequately, uncuffed tubes may need to be exchanged for another tube with a larger diameter, which sometimes requires several attempts before the appropriate size is found...
November 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29149467/geophysical-assessment-of-groundwater-potential-a-case-study-from-mian-channu-area-pakistan
#16
Muhammad Hasan, Yanjun Shang, Gulraiz Akhter, Weijun Jin
An integrated study using geophysical method in combination with pumping tests and geochemical method was carried out to delineate groundwater potential zones in Mian Channu area of Pakistan. Vertical electrical soundings (VES) using Schlumberger configuration with maximum current electrode spacing (AB/2 = 200 m) were conducted at 50 stations and 10 pumping tests at borehole sites were performed in close proximity to 10 of the VES stations. The aim of this study is to establish a correlation between the hydraulic parameters obtained from geophysical method and pumping tests so that the aquifer potential can be estimated from the geoelectrical surface measurements where no pumping tests exist...
November 17, 2017: Ground Water
https://www.readbyqxmd.com/read/29149460/the-impact-of-a-prolonged-stay-in-the-icu-on-patients-fundamental-care-needs
#17
Claire Minton, Lesley Batten, Annette Huntington
AIM: To explore patients', families', and health professionals' experiences of a long-stay patient in an intensive care unit. BACKGROUND: The fast-paced technologically driven intensive care unit environment, designed for a short patient stay, supports the provision of complex physiologically-focused care for those with life-threatening illnesses. Long stay patients with pronounced fundamental care needs fall outside predicted patient pathways, and nurses can find caring for these patients challenging...
November 17, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29149432/ebola-in-the-netherlands-2014-2015-costs-of-preparedness-and-response
#18
Anita W M Suijkerbuijk, Corien M Swaan, Marie-Josee J Mangen, Johan J Polder, Aura Timen, Wilhelmina L M Ruijs
The recent epidemic of Ebola virus disease (EVD) resulted in countries worldwide to prepare for the possibility of having an EVD patient. In this study, we estimate the costs of Ebola preparedness and response borne by the Dutch health system. An activity-based costing method was used, in which the cost of staff time spent in preparedness and response activities was calculated based on a time-recording system and interviews with key professionals at the healthcare organizations involved. In addition, the organizations provided cost information on patient days of hospitalization, laboratory tests, personal protective equipment (PPE), as well as the additional cleaning and disinfection required...
November 17, 2017: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/29149377/multi-patch-and-multi-group-epidemic-models-a-new-framework
#19
Derdei Bichara, Abderrahman Iggidr
We develop a multi-patch and multi-group model that captures the dynamics of an infectious disease when the host is structured into an arbitrary number of groups and interacts into an arbitrary number of patches where the infection takes place. In this framework, we model host mobility that depends on its epidemiological status, by a Lagrangian approach. This framework is applied to a general SEIRS model and the basic reproduction number [Formula: see text] is derived. The effects of heterogeneity in groups, patches and mobility patterns on [Formula: see text] and disease prevalence are explored...
November 17, 2017: Journal of Mathematical Biology
https://www.readbyqxmd.com/read/29149358/clinically-directed-neuroimaging-of-ophthalmoplegia
#20
REVIEW
Lucia Danieli, Margherita Montali, Luca Remonda, Hanspeter E Killer, Cesare Colosimo, Alessandro Cianfoni
PURPOSE: Ophthalmoplegia (OP) can have numerous etiologies and different clinical presentations. Most causes of OP can be narrowed down to specific anatomical locations based on clinical information. The aim of this study was to outline the different categories of diseases encountered in patients with OP, based on the location along the ocular motor pathways, and the most appropriate imaging modality for the given scenarios. METHODS: Representative neuroimaging examples of pathological processes causing OP are displayed, sequenced by anatomical location and disease category...
November 17, 2017: Clinical Neuroradiology
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