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Thoracoscopic biopsy

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https://www.readbyqxmd.com/read/29755068/-tuberculous-pleurisy-diagnosed-by-thoracoscopic-lung-biopsy
#1
Jun Yamamoto, Miho Nishiura, Takanori Ohata, Ho Namkoong, Shinji Sakaguchi, Fumitake Saito, Hideki Yuki
A 44-year-old woman was referred to our hospital with pleural effusion and unknown fever. Mycobacterium tuberculosis was not detected by culture of pleural effusion and sputum and gastric fluid. Pleural fluid was serous and exudative, and cytological examination showed no malignant cells. Computed tomography revealed a little pleural thickening of the right middle lobe and massive pleural effusion. As acute pleurisy was suspected based on the findings of imaging studies, thoracoscopy was performed under general anesthesia...
March 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29735508/carbimazole-induced-eosinophilic-pleural-effusion
#2
Chris Ferguson, Claire Bradley, Joe Kidney
We report the case of a 41-year-old woman who presented with a unilateral exudative effusion with prominent eosinophils on pleural cytology. Carbimazole had been started 4 weeks prior to presentation. No immediate cause was identified on imaging or laboratory testing. The effusion persisted at 2-month follow-up. Further investigation at this time, including autoimmune serology was negative. At 2-month follow-up, the effusion was loculated on ultrasound imaging and had a low fluid pH on diagnostic aspiration, in keeping with an empyema...
May 7, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29732192/electromagnetic-navigation-bronchoscopy-chungnam-national-university-hospital-experience
#3
Hyun Jin Cho, Md Roknuggaman, Woo Sik Han, Shin Kwang Kang, Min-Woong Kang
Background: To find small pulmonary nodules or ground grass nodules (GGNs) with video-assisted thoracoscopic surgery (VATS) is very difficult. There are several conventional methods to localize small nodules or GGNs, which require additional radiation exposure and may cause some complications such as pneumothorax or hemothorax. We aimed to evaluate the effectiveness and feasibility of electromagnetic navigational bronchoscopy-guided pulmonary localization in a minimally invasive thoracic surgery field...
April 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29730811/phlegmonous-gastritis-associated-with-advanced-esophageal-cancer
#4
Nobutoshi Hagiwara, Takeshi Matsutani, Hiroki Umezawa, Munenaga Nakamizo, Kazuhiko Yokoshima, Eriko Shinozuka, Tsutomu Nomura, Eiji Uchida
Phlegmonous gastritis is a rapidly progressive bacterial infection of the stomach wall. It has a high mortality rate and aggressive treatment, either with antibiotics or surgical resection, is required. Here, we report an extremely rare case of phlegmonous gastritis associated with advanced esophageal cancer. A 65-year-old Japanese man was urgently admitted to the hospital due to pyrexia and gastrointestinal symptoms. Abdominal computed tomography revealed widespread diffuse thickening of the gastric wall. On endoscopic examination, an ulcerative mass was detected at the lower thoracic esophagus, and a markedly elevated submucosal lesion was present in the middle of the stomach body...
May 5, 2018: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/29719802/xanthomatous-pleuritis
#5
Ranjit Kumar Singh, Sanjib Pattari
This case presentation relates to a 21 year young male, cachectic in appearance, who presented with progressive shortness of breath, and dull pain on the lower part of the chest ongoing over three months. The patient received antitubercular drugs by local physician for suspected tuberculosis with no significant improvement. He was referred to our Respiratory Department for further evaluation of his chest pain and breathlessness. His X-ray showed moderate pleural effusion on the left side which confirmed by USG chest screening which showed multiple septation with thick parietal pleura and USG abdomen was normal...
2018: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/29668616/lung-metastases-from-intracranial-bleeding-meningioma-a-case-report
#6
Su Hu, Yaqi Zhang, Yue Sun, Yang Yu, Jia Wang, Hui Dai, Feng Sun, Chunhong Hu
RATIONALE: Meningioma is slow-growing benign neoplasm that derived from the meningothelial cells of the arachnoid mater, and it is the most common type of primary brain tumor. Although cases of extracranial metastatic meningioma have been reported previously, few cases have reported the concurrent occurrence of primary meningioma with intratumoral bleeding and lung metastases. Here we report a case of meningioma with concurrent intratumoral bleeding and lung metastases. PATIENT CONCERNS: The patient was admitted to our hospital with sudden left limb paralysis combined with complaints of headache and dizziness...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29618075/thoracoscopic-rebiopsy-to-detect-the-t790m-mutation-after-postoperative-recurrence
#7
Masatsugu Hamaji, Hideki Motoyama, Toshi Menju, Toyofumi-Fengshi Chen-Yoshikawa, Makoto Sonobe, Young Hak Kim, Hiroshi Date
After pulmonary resection for non-small-cell lung cancer, some patients with postoperative recurrence and mutated epidermal growth factor receptor (EGFR) subsequently receive EGFR-tyrosine kinase inhibitors (EGFR-TKIs). Osimertinib may be efficacious if those patients become resistant to the 1st-line EGFR-TKI because of the T790M mutation. We recently performed thoracoscopic rebiopsy to detect the T790M mutation in 4 patients who became resistant to the 1st-line EGFR-TKI treatment for postoperative recurrence...
April 2, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29609018/curative-resection-of-advanced-esophageal-cancer-with-metachronous-stage-iv-breast-cancer-a-case-report
#8
Yusuke Gokon, Tadashi Sakurai, Fumiyoshi Fujishima, Yusuke Taniyama, Takahiro Heishi, Hiroshi Okamoto, Shota Maruyama, Hirotaka Ishida, Yu Onodera, Hironobu Sasano, Takashi Kamei
INTRODUCTION: Recent studies have shown the safety and efficacy of curative resection of esophageal cancer with multiple primary cancers. However, our literature search revealed no curative surgery cases for esophageal cancer in patients with multiple primary cancers with distant metastasis. CASE PRESENTATION: A 75-year-old woman visited our hospital with dysphagia. She had a history of breast cancer with multiple bone metastasis. Esophagogastroduodenoscopy revealed a circumferential mass in the upper intrathoracic esophagus...
March 19, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29592999/treatment-of-refractory-rheumatoid-pleural-effusion-with-abatacept
#9
Shunichi Fujita, Tomoyuki Mukai, Takahiko Akagi, Yoshitaka Morita
Rheumatoid pleural effusion is generally responsive to corticosteroids, but refractory cases require consideration of second-line therapy. Here we report the case of a 61-year-old man with rheumatoid arthritis (RA) who developed a large right-sided pleural effusion and was successfully treated with abatacept. Thoracocentesis showed a sterile exudate and an elevated adenosine deaminase level. The methotrexate and etanercept used to treat the RA were withheld initially while he underwent a trial of prednisolone 40 mg/day for the pleural effusion...
March 28, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29578653/diagnostic-accuracy-and-therapeutic-relevance-of-thoracoscopic-lung-biopsies-in-children
#10
Caroline Fortmann, Nicolaus Schwerk, Martin Wetzke, Nagoud Schukfeh, Benno M Ure, Jens Dingemann
INTRODUCTION: Histopathological assessment of lung biopsies does play an important diagnostic role in children's interstitial lung disease (ChILD). Thoracoscopic lung biopsy has been shown to be safe and effective. The aim of this study was to evaluate the diagnostic accuracy of thoracoscopic lung biopsies in children with ChILD. Furthermore, therapeutic relevance of the procedure, operative details, and perioperative complications of our series were investigated. METHODS: We retrospectively reviewed all consecutive thoracoscopic lung biopsies taken from children with suspected ChILD in our institution over an 11-year period...
March 26, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29577922/efficacy-and-cost-of-awake-thoracoscopy-and-video-assisted-thoracoscopic-surgery-in-the-undiagnosed-pleural-effusion
#11
Christine M McDonald, Camille Pierre, Marc de Perrot, Gail Darling, Marcelo Cypel, Andrew Pierre, Thomas Waddell, Shaf Keshavjee, Kazuhiro Yasufuku, Kasia Czarnecka-Kujawa
BACKGROUND: The study aim is to compare the diagnostic yield, safety and cost of outpatient awake thoracoscopy (AT) to video-assisted thoracoscopic surgery (VATS) pleural biopsy in undiagnosed pleural effusions. METHODS: The diagnostic yield of pleural biopsy performed by AT or VATS in patients with undiagnosed exudative pleural effusions at a tertiary Thoracic Surgery center in Canada between 2011-2015 was retrospectively evaluated. Test sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were compared...
March 22, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29535096/middle-mediastinal-schwannoma-concealed-by-asthma-and-gord
#12
Prudence Dy, Cristina Lajom, Josephino Sanchez
Neurogenic tumours of the mediastinum in adults occur most often at the posterior mediastinum, majority of which are benign of nerve sheath in origin. A 72-year-old woman, known asthmatic, presented with chronic symptoms of hoarseness, dysphagia, chest heaviness, easy fatigability, cough, epigastric pain, feeling of abdominal fullness and choking with food intake and at a supine position. Treated for other disorders, routine chest X-ray incidentally found a homogenous convex radiodensity at the right paratracheal area; mass which was also observed with CT and 18F-fludeoxyglucose-positron emission tomography/CT scan studies...
March 13, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29525761/rare-case-of-thoracic-endometriosis-presenting-with-lung-nodules-and-pneumothorax
#13
Jessica Gates, Akhilesh Sharma, Arunesh Kumar
We present the case of a 34-year-old Nigerian woman who was referred to the Respiratory team with a 12-month history of breathlessness. She was concurrently being investigated for an abdominal mass and rectal and vaginal bleeding. Consequently, she underwent cross-sectional imaging of her chest, abdomen and pelvis, revealing a small right-sided pneumothorax and right lower lobe pleural-based lesion. Shortly thereafter, she was admitted to the hospital with chest pain and required chest drain insertion. This partially treated her pneumothorax but she required referral to a cardiothoracic centre for definitive diagnosis and to manage her non-resolving pneumothorax...
March 9, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29507795/endoscopic-diagnosis-and-management-of-pleural-effusion-in-malignant-pleural-mesothelioma
#14
REVIEW
Paolo Ceruti, Sara Lonni, Francesca Baglivo, Giampietro Marchetti
Malignant pleural mesothelioma (MPM) is an asbestos-related aggressive tumor, that requires proper diagnosis and management. Symptoms are nonspecific and chest computed tomography (CT) and chest ultrasound (US) are important radiological tools in the initial workup to identify early pathological signs. Performing a medical thoracoscopy (MT) is essential for a definitive diagnosis of MPM. The procedure, integrated with a prior US, allows a global evaluation of the pleural cavity and the execution of multiple targeted biopsies, with low risk of complications...
January 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29507793/clinical-diagnosis-of-malignant-pleural-mesothelioma
#15
REVIEW
Andrea Bianco, Tullio Valente, Maria Luisa De Rimini, Giacomo Sica, Alfonso Fiorelli
Malignant pleural mesothelioma (MPM) is a tumour which, despite progress in diagnostic procedures and biomolecular research, has poor prognosis. Symptoms reflect extension of disease and include shortness of breath and chest pain. Unexplained pleural effusion and pleural pain in patients exposed to asbestos should raise the suspicion of MPM. MPM diagnosis requires imaging procedures X-ray and computed tomography (CT) scans; magnetic resonance imaging (MRI) better defines the extension of the tumor while PET scanning provides additional information on metabolic activity, metastases, and response to treatment...
January 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29497533/narrow-band-imaging-thoracoscopy-in-pleural-amyloidosis
#16
Yuki Kanno, Naoki Furuya, Mariko Okamoto, Akira Noguchi, Takeo Inoue, Masamichi Mineshita
We report the case of a 68-year-old male non-smoker suffering from shortness of breath for 1 year. He was referred to our institution for a definitive diagnosis. Both chest X-ray and computed tomography scans showed bilateral hydrothorax with no pleural thickening. We performed flexi-rigid thoracoscopic pleural biopsy on the right side with a single port under local anaesthesia. Multiple white nodules were seen in parietal and visceral pleura, and these nodules were small and flat under white light. Narrow-band imaging demonstrated pathognostic findings on parietal pleura...
April 2018: Respirology Case Reports
https://www.readbyqxmd.com/read/29486527/thoracoscopic-pleural-biopsy-improves-yield-of-xpert-mtb-rif-for-diagnosis-of-pleural-tuberculosis
#17
Devasahayam J Christopher, Sridevi Dinakaran, Richa Gupta, Prince James, Barney Isaac, Balamugesh Thangakunam
BACKGROUND AND OBJECTIVE: Extrapulmonary tuberculosis (EPTB) accounts for ~15% of all TB patients, and TB pleural effusion is the second most common site of EPTB. The diagnosis of pleural TB is challenging due to the pauci-bacillary nature of the disease. Histopathology of thoracoscopically obtained pleural biopsy provides the highest diagnostic yield. The Xpert MTB/RIF assay (Xpert) is a PCR test that can identify both Mycobacterium tuberculosis (MTB) and rifampicin resistance. Currently, there is a lack of clarity regarding the value of Xpert on pleural tissue...
February 27, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29473958/is-tissue-still-the-issue-lobectomy-for-suspicious-lung-nodules-without-confirmation-of-malignancy
#18
Suha Kaaki, Biniam Kidane, Sadeesh Srinathan, Lawrence Tan, Gordon Buduhan
BACKGROUND: Histologic confirmation of malignancy has been indicated for a suspicious lung nodule prior to resection. The purpose of this study was to determine whether or not foregoing routine tissue biopsy increased the incidence of lobectomy for benign lesions. METHODS: Retrospective cohort of 256 patients who underwent thoracoscopic or open lobectomy for a confirmed or suspected pulmonary malignancy, with or without tissue diagnosis. Clinical, radiographic, and pathologic data were compared...
February 23, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29455826/spontaneous-regression-of-primary-pulmonary-synovial-sarcoma
#19
Hiroaki Tsunezuka, Naoko Miyata, Tatsuo Furuya, Eiichi Konishi, Masayoshi Inoue
We report a rare case of primary pulmonary synovial sarcoma that underwent spontaneous regression after a transbronchial biopsy. A 38-year-old woman with a well-demarcated solitary mass shadow on chest roentgenogram was referred to us. A transbronchial biopsy was performed, and immunohistochemical results as well as detection of SYT-SSX1 (SYnovial sarcoma Translocation-Synovial Sarcoma X chromosome breakpoint) transcripts resulted in a diagnosis of synovial sarcoma. A right lower lobectomy was performed during video-assisted thoracoscopic surgery...
March 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29454123/cardiac-metastasis-from-clivus-chordoma
#20
Jun Won Kim, Chang-Ki Hong, Yoon Jin Cha, Se Hoon Kim, Chang-Ok Suh, Kyu-Sung Lee
BACKGROUND: Chordomas are rare tumors showing locally aggressive nature and high rates of local recurrences. Distant metastases are infrequently reported and cardiac metastases are extremely rare. CASE DESCRIPTION: A 32-year-old woman had been diagnosed with a large chordoma involving the clivus. She received a total removal of the tumor and adjuvant intensity-modulated radiotherapy. Four and a half years after the surgery, she presented with multifocal lesions in the ventricles and the right atrium, although an open thoracotomy revealed chronic inflammation...
May 2018: World Neurosurgery
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