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Thoracoscopic biopsy

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https://www.readbyqxmd.com/read/28105347/pulmonary-intravascular-large-b-cell-lymphoma-successfully-treated-with-rituximab-cyclophosphamide-vincristine-doxorubicin-and-prednisolone-immunochemotherapy-report-of-a-patient-surviving-for-over-1-year
#1
Shizuka Nishii-Ito, Hiroki Izumi, Hirokazu Touge, Kenichi Takeda, Yuzuru Hosoda, Akira Yamasaki, Satoshi Kuwamoto, Eiji Shimizu, Toru Motokura
A 73-year-old man with a history of lethargy, fever and dyspnea was admitted to Tottori University Hospital. A computed tomography (CT) scan revealed splenomegaly and diffusely spreading ground-glass opacities (GGOs) in both lungs. A video-assisted thoracoscopic surgery (VATS)-guided lung biopsy revealed intravascular proliferation of large atypical lymphoid cells in the arteries, veins and alveolar walls. The patient was diagnosed with intravascular large B-cell lymphoma (IVLBCL); he received 6 cycles of rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) immunochemotherapy and has remained in complete remission for >1 year...
December 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28081314/cryptogenic-organizing-pneumonia-clinical-and-radiological-features-treatment-outcomes-of-17-patients-and-review-of-the-literature
#2
Elif Yelda Niksarlıoğlu, Gülcihan Zehra Özkan, Nur Dilek Bakan, Sibel Yurt, Lütfiye Kılıç, Güngör Çamsarı
BACKGROUND/AIM: We evaluated patients with cryptogenic organizing pneumonia (COP) who attended our clinic. MATERIALS AND METHODS: We retrospectively investigated the clinical and radiological findings, diagnostic methods, treatment, and follow-up outcomes of 17 patients who had been histopathologically diagnosed with COP. RESULTS: The mean age of the patients was 49.8 ± 10.4 years. The most common symptom was cough (n = 15; 88.2%) and the most common radiological finding (n = 10) was consolidation in the inferior lobes on thoracic computed tomography...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28079597/histologic-findings-of-severe-therapy-resistant-asthma-from-video-assisted-thoracoscopic-surgery-biopsies
#3
Humberto E Trejo Bittar, Daniel Doberer, Mitra Mehrad, Diane C Strollo, Joseph K Leader, Sally Wenzel, Samuel A Yousem
The histologic changes occurring in severe/therapy-resistant asthma (SA) as defined by the European Respiratory Society/American Thoracic Society guidelines, particularly at the level of the distal airways are unknown. This study describes the clinical, radiologic, and histologic characteristics of 29 SA patients who underwent video-assisted thoracoscopic surgery lung biopsy. Pathologic observations were correlated with clinical features, especially the presence of autoimmune disease (AID) (15/29, 51.7%). Ten biopsies (10/29, 34...
February 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28066672/intraoperative-molecular-imaging-to-identify-lung-adenocarcinomas
#4
REVIEW
Andrew D Newton, Gregory T Kennedy, Jarrod D Predina, Philip S Low, Sunil Singhal
Intraoperative molecular imaging is a promising new technology with numerous applications in lung cancer surgery. Accurate identification of small nodules and assessment of tumor margins are two challenges in pulmonary resections for cancer, particularly with increasing use of video-assisted thoracoscopic surgery (VATS). One potential solution to these problems is intraoperative use of a fluorescent contrast agent to improve detection of cancer cells. This technology requires both a targeted fluorescent dye that will selectively accumulate in cancer cells and a specialized imaging system to detect the cells...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28043482/immune-response-after-radiofrequency-ablation-and-surgical-resection-in-nonsmall-cell-lung-cancer
#5
Thomas Schneider, Hans Hoffmann, Hendrik Dienemann, Ester Herpel, Claus Peter Heussel, Alexander H Enk, Sabine Ring, Karsten Mahnke
The objective includes radiofrequency ablation (RFA) of a cancerous nodule results in immunogenic cell death. Tumor antigens are presented and the inflammatory environment may help stimulate adaptive and innate antitumor immunity. The objective of this study was to investigate the immune response following RFA and subsequent surgical resection in early stage non-small cell lung cancer (NSCLC). In methods, a single-session approach of computed tomography-guided tumor biopsy with immediate frozen section (and proof of NSCLC) was performed followed by RFA of the tumor in 4 patients with a solitary pulmonary nodule...
July 2016: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28031839/a-massive-pleural-based-desmoid-tumour
#6
Talha Mahmud, Guness Mal, Farhan Ahmed Majeed, Siaw Ming Chai, Y C Gary Lee
A 49-year-old Pakistani male presented with "heaviness" in his chest. Chest radiograph and computed tomography (CT) confirmed a massive left-sided pleural-based opacity. Three years ago, he was investigated for a left-sided lymphocytic, exudative pleural effusion following an episode of dengue fever. Tube thoracostomy removed 1.3 L of fluid. Pleural biopsy and bronchial washings were non-contributory. He received empirical anti-tuberculosis treatment and remained asymptomatic until this presentation. To investigate the new pleural mass, he underwent a video-assisted thoracoscopic surgery, which revealed a 2...
January 2017: Respirology Case Reports
https://www.readbyqxmd.com/read/28031827/pemetrexed-for-epithelioid-haemangioendothelioma-of-the-pleura
#7
Shingo Kanemura, Kozo Kuribayashi, Yumiko Moriya, Shigeki Shimizu, Tohru Tsujimura, Takashi Nakano
A 31-year-old woman presented with a 2-month history of dull left back pain. Chest roentgenography revealed pleural thickening in the left lung apex, whereas chest computed tomography showed a left pleural effusion with diffuse pleural thickening. Based on these findings, malignant mesothelioma was suspected. Video-assisted thoracoscopic pleural biopsy was performed, and subsequent staining of the specimen revealed negative results for anti-cytokeratin antibodies and positive results for vascular endothelial immunohistochemical markers...
November 2016: Respirology Case Reports
https://www.readbyqxmd.com/read/28028308/metastatic-squamous-cell-carcinoma-of-the-pleura-a-rare-complication-of-hidradenitis-suppurativa
#8
Kiran Joglekar, Christopher Jackson, Dipen Kadaria, Amik Sodhi
BACKGROUND Squamous cell carcinoma (SCC), also known as Marjolin ulcer, is a rare complication of hidradenitis suppurativa (HS). Metastatic SCC from HS typically involves the axial skeleton or abdominopelvic viscera. Metastatic disease to the lungs is a rare phenomenon with only three reported cases of lung parenchyma. We present a biopsy proven case of metastatic SCC to the pleura from gluteal HS. CASE REPORT A 46-year-old male with a history of recently diagnosed Marjolin ulcer secondary to gluteal HS was transferred to our intensive care unit for acute hypoxemic respiratory failure secondary to recurrent pleural effusion...
December 28, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27941112/antisynthetase-syndrome-ass-presenting-as-acute-respiratory-distress-syndrome-ards-in-a-patient-without-myositis-features
#9
Venkat Kiran Kanchustambham, Swetha Saladi, Sarah Mahmoudassaf, Setu Patolia
A woman aged 61 years presented to the emergency room with a 1-week history of dyspnoea on exertion and dry cough. X-ray of the chest showed diffuse interstitial opacities and was started on antibiotics and furosemide, and despite these measures, patient's respiratory status worsened, prompting endotracheal intubation. CT of the chest showed diffuse bilateral ground glass opacities and underwent bronchoscope with trans-bronchial biopsy that showed chronic bronchitis. Pt was empirically started on intravenous steroids due to concerns for interstitial lung disease (ILD)...
December 9, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27822873/resection-of-an-esophageal-schwannoma-with-thoracoscopic-surgery-a-case-report
#10
Takayoshi Watanabe, Tatsuya Miyazaki, Hideyuki Saito, Tomonori Yoshida, Yuji Kumakura, Hiroaki Honjyo, Takehiko Yokobori, Makoto Sakai, Makoto Sohda, Hiroyuki Kuwano
BACKGROUND: Esophageal schwannomas are rare primary submucosal esophageal tumors. We herein report a case of an esophageal schwannoma that was difficult to diagnose. CASE PRESENTATION: A 39-year-old woman presented with chief complaints of difficulty swallowing and epigastric pain. Enhanced computed tomography of her chest revealed a tumor mass at the upper thoracic esophagus with internal heterogeneity. 18-Fluorodeoxyglucose positron emission tomography/computed tomography showed a hypermetabolic appearance matching the tumor mass; the accumulation had a maximum standardized uptake value of 5...
December 2016: Surgical Case Reports
https://www.readbyqxmd.com/read/27772589/paragonimus-kellicotti-presenting-with-hemoptysis-and-a-left-upper-lobe-mass
#11
Christopher B Horn, Nikhil R Patel, Jennifer A Hawasli, Melanie A Edwards
A 46-year-old man presented to the thoracic surgery clinic with a 6-month history of cough and hemoptysis refractory to treatment. Examination of specimens from repeated biopsies was nondiagnostic, so the patient underwent video-assisted thoracoscopic left upper lobe wedge resection. Pathologic examination revealed Paragonimus organisms, and the patient was prescribed praziquantel, with resolution of his symptoms. Although Paragonimus infections are common in Asia, they are rare in the United States despite P kellicotti being endemic...
November 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27766798/to-study-efficacy-of-medical-thoracoscopy-in-undiagnosed-pleural-effusions
#12
Sachin S Dole, Gauri P Godbole, Himanshu S Pophale
BACKGROUND: Medical thoracoscopy has received interest in recent past for diagnostic as well as therapeutic uses. In this study we describe our experience with diagnostic medical thoracoscopy in pleural effusions of undiagnosed etiology. OBJECTIVE: 1.To detect diagnostic yield of medical thoracoscopy in pleural effusions of unknown etiology. 2.To find complication rate in these patients. METHODOLOGY: In a retrospective analysis of thoracoscopic procedures performed between March 2011 and December 2014, diagnostic yield and complications of thoracoscopic pleural biopsy for achieving a diagnosis in undiagnosed pleural effusions were evaluated...
October 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27747117/smooth-muscle-tumor-originating-in-the-pleura-a-case-report-and-updated-literature-review
#13
Santiago Fabián Moscoso Martínez, Vadim Zarubin, Geethapriya Rajasekaran Rathnakumar, Alireza Zarineh
Smooth muscle tumors (SMTs) of the pleura are exceptionally rare. At present and to the best of these authors' knowledge, there are only 17 cases reported in the literature. We describe a case of a 51-year-old woman who complained of left sided pleuritic chest pain. Further, computed tomography (CT) revealed a left sided localized pleural-based mass involving the 9th rib. She underwent an interventional radiology guided percutaneous core biopsy of the lesion, which disclosed a "Smooth Muscle Tumor of Undetermined Malignant Potential (SMT-UMP)...
2016: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/27625443/thoracoscopic-evaluation-of-129-cases-having-undiagnosed-exudative-pleural-effusions
#14
Chetan Basavaraj Patil, Ramakant Dixit, Rakesh Gupta, Neeraj Gupta, Varna Indushekar
BACKGROUND: Medical thoracoscopy is a minimally invasive procedure used in diagnostic and therapeutic applications for pleural diseases. In this study, we describe our experience in the outcome and analysis of thoracoscopy in undiagnosed pleural effusion presenting to our center. MATERIALS AND METHODS: This is a prospective study conducted over last 2 years. We performed thoracoscopy in 129 cases of undiagnosed exudative pleural effusions using rigid thoracoscope...
September 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27616539/pirfenidone-treatment-in-idiopathic-pulmonary-fibrosis-nationwide-danish-results
#15
Goran Nadir Salih, Saher Burhan Shaker, Helle Dall Madsen, Elisabeth Bendstrup
BACKGROUND: Pirfenidone was approved by the European Medicines Agency and introduced in most European countries in 2011 for treatment of idiopathic pulmonary fibrosis (IPF). OBJECTIVE: To describe the national Danish experiences of pirfenidone treatment for IPF during 30 months with respect to target population, safety, adherence to the treatment and effect analysis in a well-characterised IPF population in a real-life setting. METHODS: Retrospective data collection from medical records of all patients in Denmark with IPF from 2011 to 2014...
2016: European Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27590624/two-year-follow-up-period-showing-the-natural-history-of-a-superficial-esophageal-adenocarcinoma-arising-in-a-long-segment-of-barrett-s-esophagus
#16
Junya Oguma, Soji Ozawa, Akihito Kazuno, Miho Nitta, Yamato Ninomiya, Sakura Tomita
A 55-year-old woman experienced gastrointestinal dysfunction caused by scleroderma. An initial endoscopy revealed an erosive lesion in a long segment of Barrett's esophagus, and a biopsy led to a diagnosis of ectopic gastric mucosa. Two years later, an irregular, elevated tumor developed at the same site. This tumor was suspected of having invaded the submucosal layer. A second biopsy led to a diagnosis of adenocarcinoma. The patient subsequently underwent a thoracoscopic esophagectomy. The resected specimen revealed an invasive tumor front that had invaded the deep layer of a duplicated muscularis mucosae...
October 2016: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/27577029/semi-rigid-thoracoscopic-punch-biopsy-using-a-hybrid-knife-with-a-high-pressure-water-jet-for-the-diagnosis-of-pleural-effusions
#17
Yan Yin, Ralf Eberhardt, Xiao-Bo Wang, Qiu-Yue Wang, Jian Kang, Felix J F Herth, Gang Hou
Semi-rigid thoracoscopy is an important technique in the definitive diagnosis of pleural diseases with high diagnostic sensitivity and specificity. Obtaining adequate samples from thickened pleura is the most important limitation of semi-rigid thoracoscopy with a standard flexible forceps (SFF) compared with rigid thoracoscopy, especially in patients with mesothelioma or benign fibrothorax. Developing a convenient, efficient and safe biopsy technique to obtain sufficient samples from such patients is a key topic in semi-rigid thoracoscopy...
2016: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/27549622/antemortem-diagnosis-of-pulmonary-tumor-thrombotic-microangiopathy-in-a-patient-with-recurrent-breast-cancer-a-case-report
#18
Yui Takahashi, Hironori Uruga, Takeshi Fujii, Sayaka Mochizuki, Shigeo Hanada, Hisashi Takaya, Atsushi Miyamoto, Nasa Morokawa, Atsuko Kurosaki, Kazuma Kishi
BACKGROUND: Pulmonary tumor thrombotic microangiopathy (PTTM), a rare complication of advanced cancer, is histologically characterized by tumor embolisms and fibrocellular intimal proliferation of small pulmonary arteries and arterioles. PTTM usually has an extremely poor prognosis, and antemortem diagnosis is very difficult. CASE PRESENTATION: A 65-year-old woman with a 5-year history of clinical stage IIA (T2N0M0) invasive ductal carcinoma of the left breast was hospitalized for worsening shortness of breath, hemoptysis, and cough since 2 months...
2016: BMC Cancer
https://www.readbyqxmd.com/read/27535847/single-versus-multiple-lung-biopsies-for-suspected-interstitial-lung-disease
#19
Mohammed Khalil, Michael Cowen, Mubarak Chaudhry, Mahmoud Loubani
BACKGROUND: There is a belief that in patients with suspected interstitial lung disease, multiple biopsies from different lobes are more likely to result in a diagnosis. We compared the results of single biopsies with those of multiple biopsies in terms of positive yield of histological diagnoses and the patients' postoperative outcomes. METHODS: Data of 115 patients who underwent video-assisted thoracoscopic lung biopsy, between 2009 and 2015, for suspected interstitial lung disease were analyzed retrospectively and grouped according to single or multiple lung biopsies...
October 2016: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/27527652/coexistence-of-pulmonary-lymphangioleiomyomatosis-and-pulmonary-angiomyolipoma
#20
Xuefeng Sun, Ruie Feng, Ye Zhang, Juhong Shi, Kai-Feng Xu
BACKGROUND: Lymphangioleiomyomatosis (LAM) and angiomyolipoma are two different, but related rare diseases. To the best of our knowledge, pulmonary LAM and pulmonary angiomyolipoma have not previously been observed in the same patient. CASE PRESENTATION: A 38-year-old woman presented with a dry cough and left flank pain. She had a right nephrectomy for renal angiomyolipoma 17 years ago. A magnetic resonance imaging scan demonstrated a round mass in the left kidney...
August 15, 2016: BMC Pulmonary Medicine
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