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Tanya R Copley, Marc-Olivier Duceppe, Louise S O'Donoughue
BACKGROUND: To continue to meet the increasing demands of soybean worldwide, it is crucial to identify key genes regulating flowering and maturity to expand the cultivated regions into short season areas. Although four soybean genes have been successfully utilized in early maturity breeding programs, new genes governing maturity are continuously being identified suggesting that there remains as yet undiscovered loci governing agronomic traits of interest. The objective of this study was to identify novel loci and genes involved in a diverse set of early soybean maturity using genome-wide association (GWA) analyses to identify loci governing days to maturity (DTM), flowering (DTF) and pod filling (DTPF), as well as yield and 100 seed weight in Canadian environments...
March 1, 2018: BMC Genomics
Kenji Kasubuchi, Yoshihiro Dohi, Hiroyuki Fujita, Takahiko Fukumoto
BACKGROUND: Dart-throwing motion (DTM) is an important component of wrist function and, consequently, has the potential to become an evaluation tool in rehabilitation. However, no measurement method is currently available to reliably measure range of motion (ROM) of the wrist in the DTM plane. OBJECTIVES: To determine the reliability and responsiveness of a goniometric device to measure wrist ROM in the DTM plane. METHODS: ROM of the wrist in the DTM plane was measured in 70 healthy participants...
February 26, 2018: Physiotherapy Theory and Practice
Rodrigo Iván Contreras-Soto, Freddy Mora, Fabiane Lazzari, Marco Antônio Rott de Oliveira, Carlos Alberto Scapim, Ivan Schuster
Knowledge of the genetic architecture of flowering and maturity is needed to develop effective breeding strategies in tropical soybean. The aim of this study was to identify haplotypes across multiple environments that contribute to flowering time and maturity, with the purpose of selecting desired alleles, but maintaining a minimal impact on yield-related traits. For this purpose, a genome-wide association study (GWAS) was undertaken to identify genomic regions that control days to flowering (DTF) and maturity (DTM) using a soybean association mapping panel genotyped for single nucleotide polymorphism (SNP) markers...
December 2017: Breeding Science
Xin Li, Xingtao Ou, Zhi Li, Henglu Wei, Wei Zhou, Zhemin Duan
Dynamic thermal management (DTM) mechanisms utilize embedded thermal sensors to collect fine-grained temperature information for monitoring the real-time thermal behavior of multi-core processors. However, embedded thermal sensors are very susceptible to a variety of sources of noise, including environmental uncertainty and process variation. This causes the discrepancies between actual temperatures and those observed by on-chip thermal sensors, which seriously affect the efficiency of DTM. In this paper, a smoothing filter-based Kalman prediction technique is proposed to accurately estimate the temperatures from noisy sensor readings...
February 2, 2018: Sensors
J Malte Runge, Jonas W B Lang, Athanasios Chasiotis, Jan Hofer
Researchers have long been interested in studying differences in implicit motive between different groups. Implicit motives are typically measured by scoring text that respondents have written in response to picture cues. Recently, research on the measurement of implicit motives has made progress through the application of a dynamic Thurstonian item-response theory model (DTM; Lang, 2014 ) that captures 2 basic motivational processes in motivational research: motive competition and dynamic reduction of motive strength after a motive has been acted out...
February 1, 2018: Journal of Personality Assessment
Reza Mosayebi, Vahid Jamali, Nafiseh Ghoroghchian, Robert Schober, Masoumeh Nasiri-Kenari, Mahdieh Mehrabi
In this paper, we consider abnormality detection via diffusive molecular communications (MCs) for a network consisting of several sensors and a fusion center (FC). If a sensor detects an abnormality, it injects a number of molecules into the medium which is proportional to its sensing output. Two transmission schemes for releasing molecules into the medium are considered. In the first scheme, each sensor releases a different type of molecule (DTM), whereas in the second scheme, all sensors release the same type of molecule (STM)...
December 2017: IEEE Transactions on Nanobioscience
Segun I Popoola, Aderemi A Atayero, Nasir Faruk
The behaviour of radio wave signals in a wireless channel depends on the local terrain profile of the propagation environments. In view of this, Received Signal Strength (RSS) of transmitted signals are measured at different points in space for radio network planning and optimization. However, these important data are often not publicly available for wireless channel characterization and propagation model development. In this data article, RSS data of a commercial base station operating at 900 and 1800 MHz were measured along three different routes of Lagos-Badagry Highway, Nigeria...
February 2018: Data in Brief
Ye Li, Huan Zhao, Sheng-Fei Feng, Jia-Sheng Ye, Xin-Ke Wang, Wen-Feng Sun, Peng Han, Yan Zhang
A new model, i.e., the decreasing thickness model (DTM) is proposed and employed for designing the cylindrical diffractive microlenses (CDMs). Focal performances of the designed CDMs are theoretically investigated by solving Maxwell's equations with the boundary element method. For comparison, the CDMs designed by the traditional equal thickness model (ETM) are also studied. Theoretical simulations demonstrate that focal performances of the designed CDMs are improved a lot via replacing the traditional ETM with the proposed DTM...
November 27, 2017: Scientific Reports
Jerusa Maria Oliveira, Nicole Fontes Losano, Suellen Silva Condessa, Renata Maria Pereira de Freitas, Silvia Almeida Cardoso, Mariella Bontempo Freitas, Leandro Licursi de Oliveira
Deltamethrin (DTM) is a synthetic pyrethroid insecticide highly used by farmers and home users. This pesticide has lipophilic properties that facilitate a high absorption and can cause toxicity in non-target organisms. During foraging, the fruit-eating bats Artibeus lituratus are exposed to pesticides. However, the knowledge of the toxicity of pesticides on the physiology of bats is relatively scarce. This study aimed to check the toxicity of short-term exposure to low concentration of DTM on fruit-eating bat A...
February 2018: Ecotoxicology and Environmental Safety
Patrick M Kane, Bryan G Vopat, P Kaveh Mansuripur, Michael P Gaspar, Scott W Wolfe, Joseph J Crisco, Christopher Got
PURPOSE: To identify the relative contributions of the radiocarpal (RC) and midcarpal (MC) joints to dart-thrower's motion (DTM) of the wrist. METHODS: Six cadaveric upper extremities were fixed to a custom-designed loading jig allowing for pure moment-rotation analysis in 24 different directions of wrist motion. Each specimen was tested in 3 states: intact, simulated radiocarpal fusion (sRCF) and simulated pancarpal fusion (sPCF). Moments of ± 1.5 Nm were applied at each of 24 directions for each state and the resulting wrist rotation recorded...
March 2018: Journal of Hand Surgery
Birgitta Wennberg, Gunnel Janeslätt, Anette Kjellberg, Per A Gustafsson
Specific problems with time and timing that affect daily routines, homework, school work, and social relations have been recognized in children with ADHD. The primary treatments for children with ADHD do not specifically focus on time-related difficulties. The aim of this randomized controlled study (RCT) was to investigate how multimodal interventions, consisting of training in time-processing ability (TPA) and compensation with time-assistive devices (TAD), affect TPA and daily time management (DTM) in children with ADHD and time difficulties, compared with only educational intervention...
September 27, 2017: European Child & Adolescent Psychiatry
Qian Chen, Ni Ai, Jie Liao, Xin Shao, Yufeng Liu, Xiaohui Fan
BACKGROUND: Valuable scientific results on biomedicine are very rich, but they are widely scattered in the literature. Topic modeling enables researchers to discover themes from an unstructured collection of documents without any prior annotations or labels. In this paper, taking ginseng as an example, biological dynamic topic model (Bio-DTM) was proposed to conduct a retrospective study and interpret the temporal evolution of the research of ginseng. METHODS: The system of Bio-DTM mainly includes four components, documents pre-processing, bio-dictionary construction, dynamic topic models, topics analysis and visualization...
2017: Chinese Medicine
Hanjabam Barun Sharma, Jyotsna Kailashiya
Optimal physiological and cardiovascular characteristics are essential for optimal physical performance. Different types of training regimes affect these characteristics and lead to trainee's adaptation and changes in relevant parameters. In present interventional study we have evaluated effects of six weeks sprint-strength & agility training on such parameters. Twenty four young Indian national hockey players volunteered for this study. BW(weight), BMI, BF (%body fat), LBM (lean body mass), rHR (resting heart rate), rBP (blood pressure), rDP (double-product), P/power (using Running-based Anaerobic Sprint Test), VJ (vertical jump), SP (seated shot-put test), BS (ball-hitting speed), Tm (505-agility test) & VO2max were measured, and changes (d) after specified training regime were studied...
August 26, 2017: Journal of Strength and Conditioning Research
Mateusz Wojciech Romanowski, Maja Špiritović, Radosław Rutkowski, Adrian Dudek, Włodzimierz Samborski, Anna Straburzyńska-Lupa
OBJECTIVES: This study aims to compare the effectiveness of deep tissue massage (DTM) and therapeutic massage (TM) in the management of ankylosing spondylitis (AS) patients. MATERIALS AND METHODS: This was a small, randomized clinical pilot study. Subjects were 27 men with diagnosed AS, randomly assigned to DTM group or TM group. Subjects in each group had 10 sessions of massage. Outcomes included the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), the Bath Ankylosing Spondylitis Functional Index (BASFI), Modified Schober Test, Finger to Floor Test, chest expansion, and pain intensity of lower back...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
Jae-Sung Yu, Hua-Xin Liao, Jamie Pritchett, Cindy Bowman, Callie Vivian, Robert Parks, Shi-Mao Xia, Melissa Cooper, Wilton B Williams, Mattia Bonsignori, Steven G Reed, Meng Chen, Nathan Vandergrift, Charles M Rice, Barton F Haynes
Development of a HIV-1 vaccine is a major global priority. The yellow fever virus (YFV) attenuated vaccine 17D is among the most effective of currently used vaccines. However, the stability of the YFV17D vector when carrying non-flavivirus genes has been problematic. We have constructed and expressed HIV-1 Env in YFV17D with either single transmembrane (STM) or double transmembrane (DTM) YFV E protein domains for the development of anti-HIV antibodies. Here we describe modifications of the YFV17D vector such that HIV-1 Env gp120 is expressed in up to 5 passages in Vero cells...
November 2017: Journal of Virological Methods
A M Eissa, P Wilson, C Chen, J Collins, M Walker, D M Haddleton, N R Cameron
A new facile and efficient route for the chemical functionalisation of thiol-acrylate polyHIPE materials with responsive macromolecules using the highly emissive dithiomaleimide (DTM) linker is demonstrated. Functionalisation is found to be reversible upon addition of a thiol-containing compound, glutathione, resulting in switchable surface properties including fluorescence and wettability, hence broadening the scope of applications.
August 29, 2017: Chemical Communications: Chem Comm
Vibha Anand, Amos Cahan, Soumya Ghosh was established as a web-based registry for clinical trials of human participants in 2000. Mandatory registration started in 2008. Given more than a decade of registered trials, it's important to understand the "topic" areas and their evolution over time from this resource. This information may help in identifying current knowledge gaps. We use dynamic topic model (DTM) methods to discover topics and their evolution over last 17 years. Our model suggests that there are disease or organ specific trials such as 'Cardiovascular disorders', Heart & Brain conditions', or 'Breast & Prostate cancer' as well as trials registered for general health...
2017: AMIA Summits on Translational Science Proceedings
Ana F Dias, Tony A Rodrigues, Ana G Pedrosa, Aurora Barros-Barbosa, Tânia Francisco, Jorge E Azevedo
A remarkable property of the machinery for import of peroxisomal matrix proteins is that it can accept already folded proteins as substrates. This import involves binding of newly synthesized proteins by cytosolic peroxisomal biogenesis factor 5 (PEX5) followed by insertion of the PEX5-cargo complex into the peroxisomal membrane at the docking/translocation module (DTM). However, how these processes occur remains largely unknown. Here, we used truncated PEX5 molecules to probe the DTM architecture. We found that the DTM can accommodate a larger number of truncated PEX5 molecules comprising amino acid residues 1-197 than full-length PEX5 molecules...
September 15, 2017: Journal of Biological Chemistry
Taraka Sai Pavan Grandhi, Thrimoorthy Potta, Rajeshwar Nitiyanandan, Indrani Deshpande, Kaushal Rege
Tumors undergo periods of dormancy followed by reactivation leading to metastatic disease. Arrest in the G0/G1 phase of the cell cycle and resistance to chemotherapeutic drugs are key hallmarks of dormant tumor cells. Here, we describe a 3D platform of bladder cancer cell dormancy and reactivation facilitated by a novel aminoglycoside-derived hydrogel, Amikagel. These 3D dormant tumor microenvironments (3D-DTMs) were arrested in the G0/G1 phase and were highly resistant to anti-proliferative drugs. Inhibition of targets in the cellular protein production machinery led to induction of endoplasmic reticulum (ER) stress and complete ablation of 3D-DTMs...
October 2017: Biomaterials
Manuel Freis, Thomas M Klapötke, Jörg Stierstorfer, Norbert Szimhardt
The synthesis of di(1H-tetrazol-5-yl)methane (1, 5-DTM), starting from commercially available sodium azide and malononitrile, is described. This tetrazole was characterized and investigated for use as a neutral nitrogen-rich ligand in various energetic transition metal complexes: ([CuCl2(5-DTM)2]·2H2O (2), [Co(H2O)2(5-DTM)2]Cl2 (3), [Ni(H2O)2(5-DTM)2]Cl2 (4), [Co(H2O)2(5-DTM)2](NO3)2 (6), [Ni(H2O)2(5-DTM)2](NO3)2 (7), [Zn(H2O)2(5-DTM)2](NO3)2 (8), {[Cu3(SO4)2(5-DTM-H)2(H2O)4(5-DTM)2]·2H2O}∞ (9), [Cu(H2O)2(5-DTM)2](NO3)2 (11), [Cu(NO3)2(5-DTM)2]·2H2O (12), [Cu(NO3)2(5-DTM)2] (13), [Cu(H2O)2(5-DTM)2](ClO4)2 (14), and [Cu(ClO4)2(5-DTM)2] (15)...
July 17, 2017: Inorganic Chemistry
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