keyword
MENU ▼
Read by QxMD icon Read
search

Seminal

keyword
https://www.readbyqxmd.com/read/29036635/barbara-fish-and-a-short-history-of-the-neurodevelopmental-hypothesis-of-schizophrenia
#1
Assen Jablensky, Thomas F McNeil, Vera A Morgan
The neurodevelopmental hypothesis of schizophrenia has become a paradigm broadly accepted in today's research in schizophrenia and its spectrum. This article traces the historical development of the neurodevelopmental hypothesis of schizophrenia up until the time of its explicit formulation in 1987, by Weinberger and by Murray and Lewis, with a main focus on the seminal contribution of Barbara Fish to its conception and elaboration.
July 14, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29036474/casanova-a-multiclass-support-vector-machine-model-for-the-classification-of-human-sperm-motility-patterns
#2
Summer G Goodson, Sarah White, Alicia M Stevans, Sanjana Bhat, Chia-Yu Kao, Scott Jaworski, Tamara R Marlowe, Martin Kohlmeier, Leonard McMillan, Steven H Zeisel, Deborah A O'Brien
The ability to accurately monitor alterations in sperm motility is paramount to understanding multiple genetic and biochemical perturbations impacting normal fertilization. Computer-aided sperm analysis (CASA) of human sperm typically reports motile percentage and kinematic parameters at the population level, and uses kinematic gating methods to identify subpopulations such as progressive or hyperactivated sperm. The goal of this study was to develop an automated method that classifies all patterns of human sperm motility during in vitro capacitation following the removal of seminal plasma...
October 4, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/29035835/nerve-growth-factor-beta-purified-from-bull-seminal-plasma-enhances-corpus-luteum-formation-and-conceptus-development-in-bos-taurus-cows
#3
Jamie L Stewart, Vitor R G Mercadante, Nicholas W Dias, Igor F Canisso, Peter Yau, Brian Imai, Fabio S Lima
The objective of the current study was to determine if Nerve Growth Factor-Beta (NGF), purified from bovine seminal plasma, would improve corpus luteum function and enhance conceptus development when administered to cows at artificial insemination. Angus cows (n = 60) were synchronized using a GnRH-prostaglandin and intravaginal progesterone protocol (7-day CO-Synch/CIDR) and randomly allocated to 1 of 2 treatment groups: (1) CONT- 12 mL PBS; or (2) NGF- 296 μg purified NGF in 12 mL PBS administered intramuscularly at insemination (day 0)...
October 7, 2017: Theriogenology
https://www.readbyqxmd.com/read/29034790/minimal-toxicity-after-proton-beam-therapy-for-prostate-and-pelvic-nodal-irradiation-results-from-the-proton-collaborative-group-reg001-09-trial
#4
Michael D Chuong, William Hartsell, Gary Larson, Henry Tsai, George E Laramore, Carl J Rossi, J Ben Wilkinson, Adeel Kaiser, Carlos Vargas
BACKGROUND: Proton beam therapy (PBT) reduces normal organ dose compared to intensity modulated radiation therapy (IMXT) for prostate cancer patients who receive pelvic radiation therapy. It is not known whether this dosimetric advantage results in less gastrointestinal (GI) and genitourinary (GU) toxicity than would be expected from IMXT. MATERIAL AND METHODS: We evaluated treatment parameters and toxicity outcomes for non-metastatic prostate cancer patients who received pelvic radiation therapy and enrolled on the PCG REG001-09 trial...
October 14, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/29034582/detection-of-brucella-abortus-b19-strain-dna-in-seminal-plasma-by-polymerase-chain-reaction-in-brazil
#5
D G Junqueira Junior, A M C Lima, G M S Rosinha, C E G Carvalho, C E Oliveira, C C Sanches
A total of 27 seminal plasma samples from cattle-breeding farms or semen centres located in Minas Gerais, Brazil, previously negative by serological and tested positive for Brucella spp. with primer specific for the amplification of the gene virb5 by polymerase chain reaction (PCR) were analysed for the detection of Brucella abortus DNA by PCR. It was found that nine samples (33.33%) contained B. abortus B19 strain DNA, two (7.40%) contained B. abortus DNA and five (18.51%) contained both DNA. The larger number of samples with B...
October 16, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29030317/biopsy-core-features-are-poor-predictors-of-adverse-pathology-in-men-with-grade-group-1-prostate-cancer
#6
François Audenet, Emily A Vertosick, Samson W Fine, Daniel D Sjoberg, Andrew J Vickers, Victor E Reuter, James A Eastham, Peter T Scardino, Karim A Touijer
PURPOSE: Active surveillance (AS) is often restricted to patients with low-risk prostate cancer (PCa) with three or fewer positive cores. We aimed to identify predictors of adverse pathology for low-risk PCa treated with radical prostatectomy (RP) and to determine if a threshold number of positive cores could help the decision process for AS. MATERIALS AND METHODS: A total of 3,359 men with low-risk PCa underwent RP between January 2000 and August 2016. We analyzed the relationship between biopsy core features and adverse pathology at RP, defined as grade group (GrdGrp) ≥3, seminal vesicle invasion (SVI), or lymph node involvement (LNI)...
October 10, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29029874/sperm-subpopulations-in-ejaculated-sperm-and-spermatozoa-recovered-from-ovine-epididymides-up-to-48h-after-death
#7
Tácia Gomes Bergstein-Galan, Romildo Romualdo Weiss, Luiz Ernandes Kozicki, Sony Dimas Bicudo
The objectives of this study were threefold: to identify subpopulations of sperm based on the kinetics of frozen/thawed sheep epididymal spermatozoa or semen collected with an artificial vagina; to evaluate the effects on sperm subpopulations in the thawed samples of post mortem storage at room temperature and the addition of 20% of seminal plasma to the freezing extender and to correlate the percentage of subpopulations with gestation rate following artificial intrauterine insemination. The categorization of the subpopulations was based on sperm kinetic data from Computer Assisted Sperm Analysis (CASA)...
October 5, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/29029872/inhibition-of-deubiquitinases-alters-gamete-ubiquitination-states-and-sperm-oocyte-binding-ability-in-pigs
#8
Yang Wang, Lili Zhuang, Xuan Chen, Man Xu, Zuochen Li, Yi Jin
This study was undertaken to investigate the dynamics of protein ubiquitination in pig gametes and their micro-environments, as well as to explore the action of deubiquitinases (DUBs) in sperm-oocyte binding. Protein ubiquitination states were evaluated by in the ejaculated sperm, seminal plasma, epididymal sperm, oocytes, zona pellucida (ZP) and follicular fluid (FF) by western blotting. Different concentrations of PR-619, a non-selective inhibitor of DUBs, were used to treat oocytes during in vitro maturation (IVM), the maturation rate, amount of ubiquitinated ZP proteins, and ZP solubility were assessed...
October 7, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/29028777/taboo-in-the-workplace-a-qualitative-study-of-taiwanese-nurses-not-eating-pineapple-in-clinical-practice
#9
Shu-Ling Tsai, Chang-Hsiung Tsai, Yu-Chien Hsu, Mei-Hui Hsieh, Hsia-Tzu Kao, Min-Tao Hsu
There has been an increased emphasis on nurses' mental health and well-being in the workplace. Psychologists have established a correlative link between individual's beliefs on luck and mental health. The pineapple taboo has been observed among Taiwanese hospital nurses as a prevalent superstitious belief for bringing luck or warding off increased clinical workloads, but how and why the ritual persists in the hospital workplace remains unknown. This article aims to explore the latent meaning of observance of the taboo and how it is related to nurses' clinical practice and possibly affects their mental health at work...
November 2017: Holistic Nursing Practice
https://www.readbyqxmd.com/read/29026057/pathological-outcome-for-chinese-patients-with-low-risk-prostate-cancer-eligible-for-active-surveillance-and-undergoing-radical-prostatectomy-comparison-of-six-different-active-surveillance-protocols
#10
C F Tsang, J Hl Tsu, T Ct Lai, K W Wong, B Sh Ho, A Tl Ng, W K Ma, M K Yiu
INTRODUCTION: Active surveillance is one of the therapeutic options for the management of patients with low-risk prostate cancer. This study compared the performance of six different active surveillance protocols for prostate cancer in the Chinese population. METHODS: Patients who underwent radical prostatectomy for prostate cancer from January 1998 to December 2012 at a university teaching hospital in Hong Kong were reviewed. Six active surveillance protocols were applied to the cohort...
October 13, 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/29023077/spermatogenic-and-phylo-molecular-characterizations-of-isolated-fasciola-spp-from-cattle-north-west-iran
#11
Soheila Rouhani, Saber Raeghi, Adel Spotin
BACKGROUND AND OBJECTIVE: Fascioliasis is economically important to the livestock industry that caused with Fasciola hepatica and Fasciola gigantica. The objective of this study was to identify these two species F. hepatica and F. gigantica by using nuclear and mitochondrial markers (ITS1, ND1 and CO1) and have been employed to analyze intraspecific phylogenetic relations of Fasciola spp. MATERIALS AND METHODS: Approximately 150 Fasciola specimens were collected, then stained with haematoxylin-carmine dye and observed under an optical microscope to examine for the existence of sperm...
2017: Pakistan Journal of Biological Sciences: PJBS
https://www.readbyqxmd.com/read/29022241/a-panel-of-protein-candidates-for-comprehensive-study-of-caprine-arthritis-encephalitis-cae-infection
#12
Rosivaldo Quirino Bezerra Júnior, Ângela Maria Xavier Eloy, João Ricardo Furtado, Raymundo Rizaldo Pinheiro, Alice Andrioli, Frederico Bruno Moreno, Marina Duarte Pinto Lobo, Ana Cristina O Monteiro-Moreira, Renato de Azevedo Moreira, Tatiana Maria Farias Pinto, Maria Fátima da Silva Teixeira
The caprine arthrite encephalite (CAE) is a disease that affects especially dairy goat. The virus shows compartmentalization features, that allows it to hide at certain times during the course of the disease, making it difficult to control. The present study was conducted to identify the major seminal plasma protein profile of goats infected by CAE and its associations with seroconversion using Western blotting. Two groups containing five males each, were used in this experiment. The first group was composed by seropositive animals and the control by seronegative confirmed by Western blotting and PCR...
October 12, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29021318/salinity-induced-phenotypic-plasticity-in-threespine-stickleback-sperm-activation
#13
Annette Taugbøl, Anna B Mazzarella, Emily R A Cramer, Terje Laskemoen
Phenotypic expression may be and often is influenced by an organism's developmental environment, referred to as phenotypic plasticity. The sperm cells of teleosts have been found to be inactive in the seminal plasma and are activated by osmotic shock for most fish species, through release in either hypertonic (for marine fish) or hypotonic (for freshwater fish) water. If this is the case, the regulatory system of sperm mobility should be reversed in salt- and freshwater fish. We tested this hypothesis by first activating sperm of salt- and freshwater populations of threespine stickleback in salt- and freshwater...
October 2017: Biology Letters
https://www.readbyqxmd.com/read/29021174/nutritional-geometry-of-paternal-effects-on-embryo-mortality
#14
Michal Polak, Leigh W Simmons, Joshua B Benoit, Kari Ruohonen, Stephen J Simpson, Samantha M Solon-Biet
Well-established causal links exist between maternal nutritional deficits and embryo health and viability. By contrast, environmental effects operating through the father that could influence embryo mortality have seldom been examined. Yet, ejaculates can require non-trivial resource allocation, and seminal plasma components are increasingly recognized to exert wide-ranging effects on females and offspring, so paternal dietary effects on the embryo should be expected. We test for effects of varying levels of protein (P), carbohydrate (C) and caloric load in adult male diet on embryo mortality in Drosophila melanogaster We demonstrate that macronutrient balance and caloric restriction exert significant effects, and that nutritional effects are more impactful when a prior mating has occurred...
October 11, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/29021144/metastatic-primary-seminal-vesicle-adenocarcinoma-management-of-a-rare-tumour-with-multiagent-chemotherapy-and-hormonal-therapy
#15
Hira Lal, Priyank Yadav, Rahul Jena, Manoj Jain
Primary seminal vesicle adenocarcinoma is one of the rarest genitourinary cancers. The pathogenesis is unknown and clinical manifestations are protean. There is no defined treatment for this disease and various combinations of surgery, chemotherapy, radiation therapy and hormonal therapy have been used in the past. Here, we have reported a primary seminal vesicle adenocarcinoma with hepatic metastases, managed with multiagent chemotherapy (oxaliplatin and 5-fluorouracil based) and androgen ablation (with triptorelin)...
October 10, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29020683/combination-of-androgen-deprivation-therapy-and-salvage-radiotherapy-versus-salvage-radiotherapy-alone-for-recurrent-prostate-cancer-after-radical-prostatectomy
#16
Sangjun Yoo, Dalsan You, Young Seok Kim, Jun Hyuk Hong, Hanjong Ahn, Choung-Soo Kim
INTRODUCTION: To assess the value of androgen deprivation therapy (ADT) on salvage radiotherapy (RT) in post-prostatectomy recurrent prostate cancer patients, we compared the oncologic outcomes between patients receiving RT + ADT and those receiving RT alone. MATERIALS AND METHODS: We reviewed the records of patients diagnosed with prostate cancer between 1995 and 2011, including 93 patients who underwent salvage RT and 69 patients who underwent salvage RT + ADT...
October 12, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/29019465/facile-and-controllable-electrochemical-fabrication-of-cell-adhesive-polypyrrole-electrodes-using-pyrrole-rgd-peptides
#17
Lindy K Jang, Semin Kim, Jiwon Seo, Jae Young Lee
Electrically conductive polymers, such as polypyrrole (PPy), have been widely used for the fabrication of various biosensors and tissue engineering scaffolds. For their biologically relevant applications, conductive biomaterials capable of intimate cellular interactions are highly desired. However, conventional methods to incorporate biomolecules into conductive polymers do not offer fine and easy control over the surface density of the biomolecules and/or their stability. We present a novel method to electrochemically immobilize cell adhesive Arg-Gly-Asp (RGD) ligands on PPy electrode surfaces with a simple control over the peptide surface density by varying the electrodeposition time...
October 11, 2017: Biofabrication
https://www.readbyqxmd.com/read/29017150/collection-evaluation-and-coagulum-dissolution-of-semen-from-goeldi-s-monkey-callimico-goeldii
#18
Paloma Rocha Arakaki, Fernanda Maria de Carvalho, Paulo Henrique Gomes de Castro, José Augusto Pereira Carneiro Muniz, Rodrigo Del Rio do Valle
Research on Neotropical primates' reproduction is necessary due to the lack of available information and the increasing threat to these species. Callimico goeldii is listed as Vulnerable on the IUCN Red List of Threatened Species. This study aimed to test rectal electrostimulation for semen collection and evaluate seminal characteristics. Therefore, semen from 6 captive Goeldi's monkeys was collected and, for the first time, seminal characteristics are described. Coagulum formation was noted in all ejaculates, and we obtained partial or complete liquefaction of the samples...
October 11, 2017: Folia Primatologica; International Journal of Primatology
https://www.readbyqxmd.com/read/28993556/telomere-biology-in-aging-and-cancer-early-history-and-perspectives
#19
Makoto T Hayashi
The ends of eukaryotic linear chromosomes are protected from undesired enzymatic activities by a nucleoprotein complex called the telomere. Expanding evidence indicates that telomeres have central functions in human aging and tumorigenesis. While it is undoubtedly important to follow current advances in telomere biology, it is also fruitful to be well informed in seminal historical studies for a comprehensive understanding of telomere biology, and for the anticipation of future directions. With this in mind, I here summarize the early history of telomere biology and current advances in the field, mostly focusing on mammalian studies relevant to aging and cancer...
October 6, 2017: Genes & Genetic Systems
https://www.readbyqxmd.com/read/28991236/corrigendum-an-ethnically-relevant-consensus-korean-reference-genome-is-a-step-towards-personal-reference-genomes
#20
Yun Sung Cho, Hyunho Kim, Hak-Min Kim, Sungwoong Jho, JeHoon Jun, Yong Joo Lee, Kyun Shik Chae, Chang Geun Kim, Sangsoo Kim, Anders Eriksson, Jeremy S Edwards, Semin Lee, Byung Chul Kim, Andrea Manica, Tae-Kwang Oh, George M Church, Jong Bhak
This corrects the article DOI: 10.1038/ncomms13637.
October 9, 2017: Nature Communications
keyword
keyword
87733
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"