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https://www.readbyqxmd.com/read/29054032/constipation-and-other-common-symptoms-reported-by-women-and-men-in-methadone-and-buprenorphine-maintenance-treatment
#1
Paul S Haber, Mahmoud Elsayed, David Espinoza, Nicholas Lintzeris, Anne-Sophie Veillard, Richard Hallinan
BACKGROUND: Opioid substitution treatment (OST) is often continued long-term and, therefore, opioid-associated symptoms are of interest. Symptoms associated with methadone maintenance treatment (MMT) in men are well described, but there are fewer reports concerning symptoms associated with buprenorphine maintenance treatment (BMT) and very few reports among women. METHOD: Recipients of BMT (n=113) and MMT (n=184), non-opioid users (n=105) and opioid users not receiving OST (n=87) completed the Patient Assessment of Constipation (PAC-SYM) and a general symptom checklist...
October 13, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29053912/community-based-screening-of-hepatitis-c-with-a-one-step-rna-detection-algorithm-from-dried-blood-spots-analysis-of-key-populations-in-barcelona-spain
#2
V Saludes, C Folch, A Morales-Carmona, L Ferrer, L Fernández, R Muñoz, M Jiménez, E Loureiro, P Fernández-Dávila, E Bascuñana, J Casabona, E Martró
Alternative strategies are required to enhance the diagnosis of silent hepatitis C virus (HCV) infections in hard-to-reach key populations at risk. Among them, HCV prevalence and bio-behavioural data is scarce for HIV-negative men who have sex with men (MSM) and men and trans-women sex workers. We sought to describe and assess the potential benefits of a community-based one-step HCV screening and confirmatory strategy for these populations in Barcelona. The screening strategy based on a real-time RT-PCR assay for HCV-RNA detection in dried-blood spots (DBS) was validated and implemented in addition to an antibody point-of-care test in a community centre...
October 20, 2017: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/29053737/screening-for-hiv-hepatitis-b-and-syphilis-on-dried-blood-spots-a-promising-method-to-better-reach-hidden-high-risk-populations-with-self-collected-sampling
#3
Inge H M van Loo, Nicole H T M Dukers-Muijrers, Rosalie Heuts, Marianne A B van der Sande, Christian J P A Hoebe
INTRODUCTION: Many people at high risk for sexually transmitted infections (STIs), e.g., men who have sex with men (MSM), are not optimally reached by current sexual health care systems with testing. To facilitate testing by home-based sampling or sampling in outreach setting we evaluated dried blood spots (DBS), a method for self-collected blood sampling for serological screening of HIV, hepatitis B (HBV) and syphilis. The aims of this study were to assess the acceptability and feasibility of self-collected DBS and to compare the test results for screening of HIV, HBV and syphilis from DBS with blood drawn by venous puncture...
2017: PloS One
https://www.readbyqxmd.com/read/29053483/sex-specific-outcomes-after-transcatheter-aortic-valve-replacement-a-review-of-the-literature
#4
Yasameen Azarbaijani, Kathryn O'Callaghan, William E Sanders, Changfu Wu, John Laschinger, Danica Marinac-Dabic, David G Strauss, Daniel A Canos, Robbert Zusterzeel
Transcatheter aortic valve replacement (TAVR) is a safe and effective therapy for aortic valve replacement in patients ineligible for or at high risk for surgery. However, outcomes after TAVR based on an individual's sex remain to be fully elucidated. We searched PUBMED and EMBASE using the keywords: 'transcatheter aortic valve replacement', 'transcatheter aortic valve implantation', 'sex differences', 'gender', 'sex characteristics' and collected information on baseline features, procedural characteristics and post-procedural outcomes in women...
October 9, 2017: Cardiology in Review
https://www.readbyqxmd.com/read/29053404/positive-body-image-is-positively-associated-with-hedonic-emotional-and-eudaimonic-psychological-and-social-well-being-in-british-adults
#5
Viren Swami, Laura Weis, David Barron, Adrian Furnham
Studies examining associations between positive body image and well-being have used a limited array of measures of each construct. To rectify this, we asked an online sample of 1148 UK adults to complete a range of measures of positive body image (body appreciation, body image flexibility, body pride, body acceptance from others) and a multi-dimensional measure of well-being (emotional, psychological, and social). Results showed that, once the effects of age and body mass index (BMI) had been accounted for, body appreciation significantly predicted all dimensions of well-being...
October 20, 2017: Journal of Social Psychology
https://www.readbyqxmd.com/read/29053225/histological-outcomes-of-anal-high-grade-cytopredictions
#6
Jennifer Margaret Roberts, Fengyi Jin, Isobel Mary Poynten, Carmella Law, David James Templeton, Julia Kathleen Thurloe, Suzanne Marie Garland, Andrew Edwin Grulich, Annabelle Farnsworth, Richard John Hillman
BACKGROUND: Longitudinal studies of histological outcomes after anal cytological screening in men who have sex with men (MSM) are rare. This study measured the positive predictive values (PPVs) of each level of baseline cytological abnormality in MSM in Sydney, Australia, over a 12-month period. METHODS: The Study of the Prevention of Anal Cancer is a 3-year prospective study of the natural history of anal human papillomavirus infection in MSM at least 35 years old...
October 20, 2017: Cancer
https://www.readbyqxmd.com/read/29051811/serum-uric-acid-levels-are-associated-with-homeostasis-model-assessment-in-obese-nondiabetic-patients-homa-and-uric-acid
#7
Cesar I Elizalde-Barrera, Teresa Estrada-García, Jose J Lozano-Nuevo, Ana K Garro-Almendaro, Catalina López-Saucedo, Alberto F Rubio-Guerra
BACKGROUND: Hyperuricemia leads to insulin resistance, whereas insulin resistance decreases renal excretion of uric acid. The aim of this study was to evaluate whether there is a correlation between serum uric acid levels with homeostatic model assessment (HOMA) 1 in nondiabetic patients. METHODS: We evaluated 88 nondiabetic patients, in whom uric acid levels were measured, in all of them HOMA of β-cell function (HOMA 1B) and HOMA of insulin resistance (HOMA 1IR) scores were performed...
October 2017: Therapeutic Advances in Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29050745/a-spectrum-of-retinal-vasculature-measures-and-coronary-artery-disease
#8
Sarah B Wang, Paul Mitchell, Gerald Liew, Tien Yin Wong, Kevin Phan, Aravinda Thiagalingam, Nichole Joachim, George Burlutsky, Bamini Gopinath
BACKGROUND AND AIMS: We aimed to comprehensively describe a spectrum of retinal vessel measures including fractal dimension (Df) and their associations with indices of coronary artery disease (CAD) extent and severity, as well as hypertension and diabetes. METHODS: The Australian Heart Eye Study (AHES) is an observational study that surveyed 1680 participants presenting to a tertiary referral hospital for the evaluation of potential CAD by coronary angiography. A range of newer retinal vessel geometric measures (Df, curvature tortuosity, and branching angle) were quantified from retinal photographs using semi-automated software, the Singapore 'I' Vessel Assessment (SIVA) tool...
October 10, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29049612/long-term-change-in-the-risk-of-skin-cancer-after-organ-transplantation-a-population-based-nationwide-cohort-study
#9
Syed Mohammad Husain Rizvi, Bjarte Aagnes, Hallvard Holdaas, Einar Gude, Kristin Muri Boberg, Øystein Bjørtuft, Per Helsing, Torbjørn Leivestad, Bjørn Møller, Petter Gjersvik
Importance: The high risk of skin cancer after organ transplantation is a major clinical challenge and well documented, but reports on temporal trends in the risk of posttransplant cutaneous squamous cell carcinoma (SCC) are few and appear contradictory. Objective: To study temporal trends for the risk of skin cancer, particularly SCC, after organ transplantation. Design, Setting, and Participants: Population-based, nationwide, prospective cohort study of 8026 patients receiving a kidney, heart, lung, or liver transplant in Norway from 1968 through 2012 using patient data linked to a national cancer registry...
October 18, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/29049523/oral-human-papillomavirus-infection-differences-in-prevalence-between-sexes-and-concordance-with-genital-human-papillomavirus-infection-nhanes-2011-to-2014
#10
Kalyani Sonawane, Ryan Suk, Elizabeth Y Chiao, Jagpreet Chhatwal, Peihua Qiu, Timothy Wilkin, Alan G Nyitray, Andrew G Sikora, Ashish A Deshmukh
Background: The burden of human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC) is disproportionately high among men, yet empirical evidence regarding the difference in prevalence of oral HPV infection between men and women is limited. Concordance of oral and genital HPV infection among men is unknown. Objective: To determine the prevalence of oral HPV infection, as well as the concordance of oral and genital HPV infection, among U.S...
October 17, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/29049519/association-of-bone-mineral-density-with-the-risk-of-intracranial-aneurysm
#11
Yong-Won Shin, Kyung-Il Park, Jangsup Moon, Soon-Tae Lee, Kon Chu, Sang Kun Lee, Jae-Kyu Roh, Keun-Hwa Jung
Importance: Disruption of extracellular matrix integrity is critically involved in both intracranial aneurysm and bone fragility. Furthermore, both intracranial aneurysm and osteoporosis have a female predominance, and sex hormones are considered to affect this discrepancy. Objective: To evaluate the association between bone mineral density and intracranial aneurysm. Design, Setting, and Participants: A cross-sectional study conducted with 14 328 patients who underwent brain magnetic resonance angiography and bone mineral densitometry as a part of a health examination at a specialized center for comprehensive health examination in Seoul, the largest metropolitan area in the Republic of Korea, between December 2004 and November 2015...
October 16, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29049480/interpreting-biomarker-results-in-individual-patients-with-mild-cognitive-impairment-in-the-alzheimer-s-biomarkers-in-daily-practice-abide-project
#12
Ingrid S van Maurik, Marissa D Zwan, Betty M Tijms, Femke H Bouwman, Charlotte E Teunissen, Philip Scheltens, Mike P Wattjes, Frederik Barkhof, Johannes Berkhof, Wiesje M van der Flier
Importance: Biomarkers do not determine conversion to Alzheimer disease (AD) perfectly, and criteria do not specify how to take patient characteristics into account. Consequently, biomarker use may be challenging for clinicians, especially in patients with mild cognitive impairment (MCI). Objective: To construct biomarker-based prognostic models that enable determination of future AD dementia in patients with MCI. Design, Setting, and Participants: This study is part of the Alzheimer's Biomarkers in Daily Practice (ABIDE) project...
October 16, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29049464/clustering-of-neuropsychiatric-disease-in-first-degree-and-second-degree-relatives-of-patients-with-amyotrophic-lateral-sclerosis
#13
Margaret O'Brien, Tom Burke, Mark Heverin, Alice Vajda, Russell McLaughlin, John Gibbons, Susan Byrne, Marta Pinto-Grau, Marwa Elamin, Niall Pender, Orla Hardiman
Importance: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative condition primarily involving the motor system. There is increasing epidemiologic evidence of an association between ALS and a wider spectrum of neurodegenerative and neuropsychiatric disorders among family members, including schizophrenia and psychotic illness and suicidal behavior. Objective: To examine the frequency and range of neuropsychiatric conditions that occur within individual first-degree and second-degree relatives of patients with ALS...
October 16, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29049457/association-of-patient-frailty-with-increased-morbidity-after-common-ambulatory-general-surgery-operations
#14
Carolyn D Seib, Holly Rochefort, Kathryn Chomsky-Higgins, Jessica E Gosnell, Insoo Suh, Wen T Shen, Quan-Yang Duh, Emily Finlayson
Importance: Frailty is a measure of decreased physiological reserve that is associated with morbidity and mortality in major elective and emergency general surgery operations, independent of chronological age. To date, the association of frailty with outcomes in ambulatory general surgery has not been established. Objective: To determine the association between frailty and perioperative morbidity in patients undergoing ambulatory general surgery operations. Design, Setting, and Participants: A retrospective cohort study was conducted of 140 828 patients older than 40 years of age from the 2007-2010 American College of Surgeons National Surgical Quality Improvement Program Participant Use File who underwent ambulatory and 23-hour-stay hernia, breast, thyroid, or parathyroid surgery...
October 11, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/29049270/adipokine-profile-in-patients-with-type-2-diabetes-depends-on-degree-of-obesity
#15
Joanna Kocot, Piotr Dziemidok, Małgorzata Kiełczykowska, Anna Hordyjewska, Grzegorz Szcześniak, Irena Musik
BACKGROUND The fast pace of life, promoting fast food consumption and low physical activity, has resulted in obesity and/or diabetes as being serious social problems. The aim of the present study was to evaluate concentrations of selected adipokines (leptin, adiponectin, resistin, and visfatin) and to assess the leptin/adiponectin ratio in plasma of type 2 diabetes (T2D) patients in relation to degree of obesity. MATERIAL AND METHODS The study comprised 92 T2D subjects divided into 4 groups according to BMI value - I (normal body weight), II (overweight), III (obesity), and IV (severe obesity) - and 20 healthy volunteers (control group)...
October 19, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29049238/age-and-sex-related-differences-in-corneal-epithelial-thickness-measured-with-spectral-domain-anterior-segment-optical-coherence-tomography-among-egyptians
#16
Magda Mahmoud Samy, Yasmine Maher Shaaban, Tamer Abdel Fattah Badran
Is to measure the corneal epithelial thickness (CET) in a group of healthy Egyptian population and to investigate its variation with age and sex using spectral domain-anterior segment optical coherence tomography (SD-AS-OCT).This cross-sectional observational study includes 240 eyes of 120 healthy individuals (60 men, 60 women). Each gender was divided into 4 equal groups according to age as follows (18-29 years), (30-44 years), (45-59 years), and (60-80 years). The CET in 17 points over a corneal diameter of 6...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29048965/the-effectiveness-of-hiv-prevention-interventions-in-socioeconomically-disadvantaged-ethnic-minority-women-a-systematic-review-and-meta-analysis
#17
Isabel Ruiz-Perez, Matthew Murphy, Guadalupe Pastor-Moreno, Antonio Rojas-García, Miguel Rodríguez-Barranco
BACKGROUND: Surveys in the United States and Europe have shown a plateau of new HIV cases, with certain regions and populations disproportionately affected by the disease. Ethnic minority women and socioeconomically disadvantaged groups are disproportionately affected by HIV. Previous reviews have focused on prevention interventions targeting ethnic minority men who have sex with men, have not accounted for socioeconomic status, or have included only interventions carried out in clinical settings...
October 19, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/29048765/ageratum-conyzoides-l-inhibits-5-alpha-reductase-gene-expression-in-human-prostate-cells-and-reduces-symptoms-of-benign-prostatic-hypertrophy-in-otherwise-healthy-men-in-a-double-blind-randomized-placebo-controlled-clinical-study
#18
Matthew Detering, Elizabeth Steels, Sundar Rao Koyyalamudi, Elena Allifranchini, Elena Bocchietto, Luis Vitetta
A double-blind, randomized, placebo-controlled clinical trial assessed the efficacy and safety of Ageratum conyzoides in treating benign prostatic hypertrophy (BPH). In this study, 109 men with medically diagnosed BPH, aged 41-76 years, were administered the investigational product, A. conyzoides extract at a dose of 250 mg/d or placebo, q.d. for 12 weeks. The primary outcome measures were the International Prostate Symptom Score (IPSS), daily urinary frequency and safety evaluations. The secondary outcome measures were testosterone, dihydrotestosterone, oestradiol, sex hormone binding globulin (SHBG), Dehydroepiandrosterone sulfate (DHEA-S) and cortisol levels, and prostate specific antigen (PSA), lipids, blood glucose, the Aging Male's Symptom (AMS) Score and sexual function assessed by Derogatis Interview for Sexual Functioning-Self Report (DISF-SR)...
October 19, 2017: BioFactors
https://www.readbyqxmd.com/read/29048313/knowledge-and-attitudes-about-abortion-among-undergraduate-students
#19
David Alvargonzález
BACKGROUND: This study examined attitudes towards and knowledge about abortion among undergraduate students doing eleven different subjects. The differences in attitudes and knowledge about abortion according to gender, religious and political affiliation, religiosity, sexual orientation, number of sex partners and previous sexual experience were also considered. METHOD: 1,025 undergraduate students (58.34% women and 41.66% men; mean age 20.18) completed the following instruments: an adaptation of the Abortion Attitudes Scale by Hill, and an adaptation of Abortion Knowledge Test by Esposito and Basow...
November 2017: Psicothema
https://www.readbyqxmd.com/read/29048252/stigma-communication-surrounding-prep-the-experiences-of-a-sample-of-men-who-have-sex-with-men
#20
Joseph Schwartz, Josh Grimm
HIV is a serious problem in the USA, particularly for men who have sex with men (MSM). A new means of HIV prevention, called pre-exposure prophylaxis (PrEP), has been shown to be highly effective. However, in spite of earning FDA approval, adoption of PrEP by MSM has been limited. The purpose of this study was to examine the experiences of a sample of 38 MSM who have adopted PrEP, focusing on communication with healthcare providers and social networks. In-depth interviews were used to collect data. Findings revealed that stigmatization by healthcare providers as well as stigmatization by other MSM was a relatively common experience for participants...
October 19, 2017: Health Communication
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