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https://www.readbyqxmd.com/read/29656624/health-care-burden-of-spinal-diseases-in-the-republic-of-korea-analysis-of-a-nationwide-database-from-2012-through-2016
#1
Chang-Hyun Lee, Chun Kee Chung, Chi Heon Kim, Ji-Woong Kwon
OBJECTIVE: This study aimed to determine the incidence and analyze trends related to spinal diseases based on a national database in the Republic of Korea (ROK) and to elucidate the healthcare burden that will serve as a useful resource for researchers, clinicians, and patients. METHODS: This study was a retrospective analysis of data obtained from Healthcare Bigdata Hub, the Korean Statistical Information Service, and Open Data Portal from 2012 through 2016. The main disease codes for spinal diseases (M40-M54) were used for identification of these conditions...
March 2018: Neurospine
https://www.readbyqxmd.com/read/29656588/the-use-of-funnel-plots-with-regression-as-a-tool-to-visually-compare-hiv-treatment-outcomes-between-centres-adjusting-for-patient-characteristics-and-size-a-uk-collaborative-hiv-cohort-study
#2
M Gompels, S Michael, S Jose, T Hill, R Trevelion, C A Sabin, M T May
OBJECTIVES: A measure used for assessing the effectiveness of HIV care and comparing clinical centres is the proportion of people starting antiretroviral therapy (ART) with viral suppression (VS) after 1 year. We propose a method that adjusts for patients' demographic characteristics, and visually compares this measure between different sites accounting for centre size. METHODS: We analysed viral load measurements for UK Collaborative HIV Cohort (UK CHIC) patients starting ART between 2006 and 2013...
April 14, 2018: HIV Medicine
https://www.readbyqxmd.com/read/29655934/age-difference-between-heterosexual-partners-in-britain-implications-for-the-spread-of-chlamydia-trachomatis
#3
Joost H Smid, Victor Garcia, Nicola Low, Catherine H Mercer, Christian L Althaus
Heterosexual partners often differ in age. Integrating realistic patterns of sexual mixing by age into dynamic transmission models has been challenging. The effects of these patterns on the transmission of sexually transmitted infections (STI) including Chlamydia trachomatis (chlamydia), the most common bacterial STI are not well understood. We describe age mixing between new heterosexual partners using age- and sex-specific data about sexual behavior reported by people aged 16-63 years in the 2000 and 2010 British National Surveys of Sexual Attitudes and Lifestyles...
March 31, 2018: Epidemics
https://www.readbyqxmd.com/read/29655763/sleeping-oxygen-saturation-rapid-eye-movement-sleep-and-the-adaptation-of-postprandial-metabolic-function-in-insulin-sensitive-and-resistant-individuals-without-diabetes
#4
Karin A Garcia, William K Wohlgemuth, Ele Ferrannini, Andrea Mari, Alex Gonzalez, Armando J Mendez, Roberto Bizzotto, Jay S Skyler, Neil Schneiderman, Barry E Hurwitz
AIMS: Sleeping oxygen saturation (SaO2 ) and sleep stage duration have been linked with prediabetic alterations but the pathogenic pathways are not well understood. This study of insulin sensitive and resistant adults examined the effect on postprandial metabolic regulation of repeated mixed-meal challenges of different carbohydrate loading. The aim was to examine whether the relationship between lower sleeping oxygen saturation (SaO2 ) and poorer fasting and postprandial metabolic function may be linked with reduced slow wave sleep (SWS) and rapid eye movement (REM) duration, independent of age, sex and total adiposity...
April 12, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29655393/seasonal-influenza-among-children-diagnosed-by-their-guardians-a-small-pilot-study-in-japan
#5
Hiroki Maita, Tadashi Kobayashi, Hiroshi Osawa, Hiroyuki Kato
AimWe aimed to elucidate the accuracy and optimal cut-off point of the self-diagnosis of influenza and the associated clinical symptoms of children by their guardians, compared with those of the rapid influenza diagnostic test (RIDT). BACKGROUND: Seasonal influenza is a common outpatient problem during the winter season. A paediatric influenza epidemic has socio-economic impacts like temporary school closure, school event cancellations, and unscheduled work absences among parents. Hence, early identification and assessment of influenza to prevent its spread is important from a societal perspective...
April 15, 2018: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/29653030/sex-modulates-the-association-of-fibroblast-growth-factor-21-with-end-stage-renal-disease-in-asian-people-with-type-2-diabetes-a-6-3-year-prospective-cohort-study
#6
Jian-Jun Liu, Sylvia Liu, Robin Wm Choo, Shiou Liang Wee, Aimin Xu, Su Chi Lim
AIM: To study whether plasma fibroblast growth factor 21 independently predicts the risk of end-stage renal disease in Asian people with Type 2 diabetes. METHODS: In this prospective cohort study, 1700 Asian people with Type 2 diabetes were followed for a mean of 6.3 years in a regional hospital in Singapore. Incident end-stage renal disease was identified by linkage with a national renal registry. The association of baseline fibroblast growth factor 21 levels with risk of progression to end-stage renal disease was studied using survival analyses...
April 13, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29652920/association-of-renal-hyperfiltration-with-incident-proteinuria-a-nationwide-registry-study
#7
Seung Min Lee, Ju-Young Park, Min-Su Park, Jong Heon Park, Minseon Park, Hyung-Jin Yoon
To elucidate the association between renal hyperfiltration (RHF) and incident proteinuria, the data from 11,559,520 Korean adults who had undergone health screenings ≥ 3 times between 2009 and 2014 and had glomerular filtration rate (GFR) ≥60 mL/min/1.73m2 and negative dipstick test for proteinuria at baseline, were retrospectively analyzed. GFR was estimated with the Chronic Kidney Disease Epidemiology Collaboration equation based on serum creatinine, and RHF was defined as GFR >95th percentile adjusted for sex, age, body size, and diabetes and/or hypertension medication...
2018: PloS One
https://www.readbyqxmd.com/read/29652898/tooth-loss-and-pneumonia-mortality-a-cohort-study-of-japanese-dentists
#8
Shino Suma, Mariko Naito, Kenji Wakai, Toru Naito, Masaaki Kojima, Osami Umemura, Makoto Yokota, Nobuhiro Hanada, Takashi Kawamura
Although associations between oral health and pneumonia have been reported in previous studies, particularly in the institutionalized elderly, few prospective studies have investigated the association between oral condition and pneumonia among community-dwelling people and whether the findings among inpatients or patients in nursing homes are applicable to the general population is still unclear. The oral bacteria propagated in the periodontal regions may drop into the lung and increase the risk of pneumonia...
2018: PloS One
https://www.readbyqxmd.com/read/29652650/the-alcohol-contexts-of-consent-wanted-sex-sexual-pleasure-and-sexual-assault-results-from-a-probability-survey-of-undergraduate-students
#9
Debby Herbenick, Tsung-Chieh Jane Fu, Brian Dodge, J Dennis Fortenberry
OBJECTIVE: To examine, in a probability sample of undergraduate students, characteristics of students' most recent sexual experiences (including alcohol use) as well as their experiences with non-consensual sex. PARTICIPANTS: In January and February 2015, 22,046 students were invited to participate in an anonymous, cross-sectional, Internet-based survey; 7,032 surveys were completed (31.9%). METHODS: Measures included background characteristics (age, gender, sexual orientation), most recent sexual event items (sexual pleasure, wantedness, alcohol use), and experiences with nonconsensual sex (since college and lifetime)...
April 13, 2018: Journal of American College Health: J of ACH
https://www.readbyqxmd.com/read/29651646/an-examination-of-gay-couples-motivations-to-use-or-forego-pre-exposure-prophylaxis-expressed-during-couples-hiv-testing-and-counseling-chtc-sessions
#10
Tyrel J Starks, Kendell M Doyle, Ore Shalhav, Steven A John, Jeffrey T Parsons
While many gay couples perceive themselves to have little risk for HIV transmission, research estimates that 35-68% of new HIV infections are transmitted within main partnerships. Pre-exposure prophylaxis (PrEP) is recommended for those partnered gay and bisexual men (GBM) who engage in sex outside their primary relationship or who have an HIV-positive partner. There is reason to believe that couples' sero-status and sexual agreement will shape perceptions of PrEP's personal relevance among gay couples. The current study examined motivations for and ambivalence towards PrEP uptake reported in a sample of 67 gay couples during completion of a brief CDC-recommended prevention intervention: Couples HIV Testing and Counseling...
April 12, 2018: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/29650708/outcomes-in-asymptomatic-severe-aortic-stenosis-with-preserved-ejection-fraction-undergoing-rest-and-treadmill-stress-echocardiography
#11
Chetan P Huded, Ahmad Masri, Kenya Kusunose, Andrew L Goodman, Richard A Grimm, A Marc Gillinov, Douglas R Johnston, L Leonardo Rodriguez, Zoran B Popovic, Lars G Svensson, Brian P Griffin, Milind Y Desai
BACKGROUND: In asymptomatic patients with severe aortic stenosis and preserved left ventricular ejection fraction, we sought to assess the incremental prognostic value of resting valvuloarterial impedence (Zva) and left ventricular global longitudinal strain (LV-GLS) to treadmill stress echocardiography. METHODS AND RESULTS: We studied 504 such patients (66±12 years, 78% men, 32% with coronary artery disease who underwent treadmill stress echocardiography between 2001 and 2012...
April 12, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29650248/prevalence-and-risk-factors-of-chronic-obstructive-pulmonary-disease-in-china-the-china-pulmonary-health-cph-study-a-national-cross-sectional-study
#12
Chen Wang, Jianying Xu, Lan Yang, Yongjian Xu, Xiangyan Zhang, Chunxue Bai, Jian Kang, Pixin Ran, Huahao Shen, Fuqiang Wen, Kewu Huang, Wanzhen Yao, Tieying Sun, Guangliang Shan, Ting Yang, Yingxiang Lin, Sinan Wu, Jianguo Zhu, Ruiying Wang, Zhihong Shi, Jianping Zhao, Xianwei Ye, Yuanlin Song, Qiuyue Wang, Yumin Zhou, Liren Ding, Ting Yang, Yahong Chen, Yanfei Guo, Fei Xiao, Yong Lu, Xiaoxia Peng, Biao Zhang, Dan Xiao, Chung-Shiuan Chen, Zuomin Wang, Hong Zhang, Xiaoning Bu, Xiaolei Zhang, Li An, Shu Zhang, Zhixin Cao, Qingyuan Zhan, Yuanhua Yang, Bin Cao, Huaping Dai, Lirong Liang, Jiang He
BACKGROUND: Although exposure to cigarette smoking and air pollution is common, the current prevalence of chronic obstructive pulmonary disease (COPD) is unknown in the Chinese adult population. We conducted the China Pulmonary Health (CPH) study to assess the prevalence and risk factors of COPD in China. METHODS: The CPH study is a cross-sectional study in a nationally representative sample of adults aged 20 years or older from ten provinces, autonomous regions, and municipalities in mainland China...
April 9, 2018: Lancet
https://www.readbyqxmd.com/read/29649433/repurposing-sex-steroids-and-related-drugs-as-potential-treatment-for-parkinson-s-disease
#13
REVIEW
Mélanie Bourque, Marc Morissette, Thérèse Di Paolo
Parkinson's disease (PD) is a neurodegenerative disorder for which a greater prevalence and incidence is described in men. This suggests a protective effect of sex hormones in the brain. Therefore, steroids and drugs to treat endocrine conditions could have additional application for PD. Here, we review the protective effect of sex hormones, particularly estrogens, progesterone, androgens and dehydroepiandrosterone, in animal models of PD and also in human studies. Data also support that drugs affecting estrogen neurotransmission such as selective estrogen receptor modulators or affecting steroid metabolism with 5α-reductase inhibitors could be repositioned for treatment of PD...
April 9, 2018: Neuropharmacology
https://www.readbyqxmd.com/read/29649075/barriers-to-hiv-testing-among-men-who-have-sex-with-men-in-india-reached-online-implications-for-interventions
#14
Viraj V Patel, Alpana Dange, Shruta Rawat, Julia H Arnsten, Christopher Piña, Sarit A Golub, Rohan Pujari, Ankit Trivedi, Jack Harrison-Quintana, Ken H Mayer
No abstract text is available yet for this article.
April 10, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29649036/association-between-alexithymia-and-risk-of-incident-cardiovascular-diseases-in-the-suppl%C3%A3-mentation-en-vitamines-et-min%C3%A3-raux-antioxydants-su-vi-max-cohort
#15
Emmanuel Wiernik, Cédric Lemogne, Léopold Fezeu, Nathalie Arnault, Serge Hercberg, Emmanuelle Kesse-Guyot, Pilar Galan
OBJECTIVE: Although alexithymia has been suggested to be associated with cardiovascular diseases, studies are scarce and a causal relationship is questionable. This study explored the prospective association between alexithymia and cardiovascular events in middle-aged participants without cardiovascular history at baseline. METHODS: The 26-item Toronto Alexithymia Scale (TAS-26) was completed by 5,586 participants of the French Supplémentation en Vitamines et Minéraux AntioXydants (SU...
April 11, 2018: Psychosomatic Medicine
https://www.readbyqxmd.com/read/29648701/chronological-changes-in-the-epidemiological-characteristics-of-upper-urinary-tract-urolithiasis-in-japan
#16
Shinichi Sakamoto, Katsuhito Miyazawa, Takahiro Yasui, Taro Iguchi, Misuzu Fujita, Hiroaki Nishimatsu, Takuro Masaki, Toru Hasegawa, Hatsuki Hibi, Takashi Arakawa, Ryosuke Ando, Yoshinari Kato, Noritaka Ishito, Satoshi Yamaguchi, Ryoji Takazawa, Masao Tsujihata, Tadashi Matsuda, Koichiro Akakura, Akira Hata, Tomohiko Ichikawa
OBJECTIVES: To assess epidemiological and chronological trends of upper urinary tract stones in Japan in 2015. METHODS: Patients with a first episode of upper urinary tract stones in 2015 were enrolled in this nationwide survey. The study included all hospitals approved by the Japanese Board of Urology, therefore covering most of the hospitals where urologists practice in Japan. The annual incidence and composition of urolithiasis were evaluated by age and sex. These results were compared with the previous results of the nationwide surveys from 1965 to 2005 to analyze temporal trends...
April 2018: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29648576/life-space-mobility-in-parkinson-s-disease-associations-with-motor-and-non-motor-symptoms
#17
Merja Rantakokko, Susanne Iwarsson, Björn Slaug, Maria H Nilsson
Background: To describe life-space mobility and explore associations of motor and non-motor symptoms with life-space mobility in people with Parkinson's disease (PD). Methods: 164 community-dwelling persons with PD (mean age 71.6 years, 64.6% men) received a postal survey and a subsequent home visit. Motor assessments included perceived walking difficulties (Walk-12G), mobility (Timed Up and Go test), motor symptoms (UPDRS-III) and freezing of gait (item 3, FOG-Qsa)...
April 10, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29645080/risk-of-oral-tongue-cancer-among-immunocompromised-transplant-recipients-and-human-immunodeficiency-virus-infected-individuals-in-the-united-states
#18
Joseph E Tota, Eric A Engels, Margaret M Madeleine, Christina A Clarke, Charles F Lynch, Ana P Ortiz, Brenda Y Hernandez, Anil K Chaturvedi
BACKGROUND: Oral tongue cancer incidence has increased among whites in the United States; however, the cause remains unknown. If an infectious agent is implicated, then elevated risk would be expected among immunosuppressed individuals. METHODS: By using population-based registry linkage information from the US Transplant Cancer Match and human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) Cancer Match studies, the authors examined the risk of oral tongue squamous cell carcinoma (SCC) among immunocompromised transplantation recipients and HIV-infected individuals...
April 12, 2018: Cancer
https://www.readbyqxmd.com/read/29644167/chronic-scrotal-pain-may-lead-to-reduced-sexual-function-and-interest-while-sexual-activity-may-worsen-chronic-scrotal-pain-double-jeopardy
#19
Aosama Aljumaily, Hind Abdul Jaleel Al-Khazraji, Allan Gordon, Susan Lau, Keith Allen Jarvi
Background: While it is recognized that chronic pain may adversely impact sexual function and activity in men and we also recognize that sexual activity may worsen the pain for men with chronic scrotal pain (CSP), the effect on sexual functioning and conversely the impact of sex on CSP has not previously been documented. Methods: Retrospective analysis of a prospectively collected database. Results: From Feb 2014 to Sep 2015, a total of 128 men presenting for assessment of CSP completed all or parts of a standardized questionnaire...
March 2018: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29643940/the-impact-of-a-disease-management-programme-for-type-2-diabetes-on-health-related-quality-of-life-multilevel-analysis-of-a-cluster-randomised-controlled-trial
#20
Sigrid Panisch, Tim Johansson, Maria Flamm, Henrike Winkler, Raimund Weitgasser, Andreas C Sönnichsen
Background: Type 2 diabetes is a chronic disease associated with poorer health outcomes and decreased health related quality of life (HRQoL). The aim of this analysis was to explore the impact of a disease management programme (DMP) in type 2 diabetes on HRQoL. A multilevel model was used to explain the variation in EQ-VAS. Methods: A cluster-randomized controlled trial-analysis of the secondary endpoint HRQoL. Our study population were general practitioners and patients in the province of Salzburg...
2018: Diabetology & Metabolic Syndrome
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