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https://www.readbyqxmd.com/read/27914137/is-vitamin-d-an-independent-risk-factor-of-nonalcoholic-fatty-liver-disease-a-cross-sectional-study-of-the-healthy-population
#1
Danbee Park, Hyuktae Kwon, Seung Won Oh, Hee Kyung Joh, Seung Sik Hwang, Jin Ho Park, Jae Moon Yun, Hyejin Lee, Goh Eun Chung, Sangjoon Ze, Jae Hong Park, Yeseul Bae, Arang Lee
The association between vitamin D levels and nonalcoholic fatty liver disease (NAFLD) has been recognized. However, few studies showed independent associations between vitamin D deficiency and NAFLD after a sex-related adjustment for metabolic factors. We aimed to study whether vitamin D deficiency is an independent risk factor of NAFLD even after controlling for metabolic syndrome and visceral fat in both sexes. In this cross-sectional study, 7,514 Korean adults (5,278 men, 2,236 women) participated in a health check-up program...
January 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27914134/association-between-lumbar-bone-mineral-density-and-carotid-intima-media-thickness-in-korean-adults-a-cross-sectional-study-of-healthy-twin-study
#2
Jinyoung Shin, Joo Hyun Park, Yun Mi Song, Kayoung Lee, Joohon Sung
Bone mineral density (BMD) has been suggested to be associated with atherosclerosis. In the present study, we evaluated the association between lumbar BMD and the segments of carotid intima-media thickness (CIMT), a surrogate marker of subclinical atherosclerosis, in Korean adults, with consideration of sex and menopause status. Among 1,679 Korean adults who enrolled in a Healthy Twin Study, 723 men, 690 premenopausal women, and 266 postmenopausal women measured the CIMT at the common carotid artery intima-media thickness (CCA-IMT), carotid bifurcation intima-media thickness (BIF-IMT), internal carotid artery intima-media thickness (ICA-IMT) using B-mode ultrasound and lumbar BMD using dual-energy X-ray absorptiometry...
January 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27913943/the-cost-effectiveness-of-interventions-targeting-lifestyle-change-for-the-prevention-of-diabetes-in-a-swedish-primary-care-and-community-based-prevention-program
#3
Anne Neumann, Lars Lindholm, Margareta Norberg, Olaf Schoffer, Stefanie J Klug, Fredrik Norström
BACKGROUND: Policymakers need to know the cost-effectiveness of interventions to prevent type 2 diabetes (T2D). The objective of this study was to estimate the cost-effectiveness of a T2D prevention initiative targeting weight reduction, increased physical activity and healthier diet in persons in pre-diabetic states by comparing a hypothetical intervention versus no intervention in a Swedish setting. METHODS: A Markov model was used to study the cost-effectiveness of a T2D prevention program based on lifestyle change versus a control group where no prevention was applied...
December 2, 2016: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/27913795/prevalence-of-sti-symptoms-and-high-levels-of-stigma-in-sti-healthcare-among-men-who-have-sex-with-men-in-dar-es-salaam-tanzania-a-respondent-driven-sampling-study
#4
Michael W Ross, Markus Larsson, Joyce E Nyoni, Anette Agardh
Symptoms of sexually transmitted infections (STIs), whether they are presented for treatment or diagnosis, and how they are received by the clinician where they are presented, may be concomitants of stigma associated with homosexuality in homophobic climates. We analyzed respondent-driven sampling data from a study on 200 young men who have sex with men (MSM) in Dar es Salaam, Tanzania to examine sample prevalence, treatment and clinician response to 10 symptoms potentially associated with STIs. Survey measures included 10 self-reported STI symptoms, further specified according to location (genital, anal, oral), further specified according to place of diagnosis, place of, treatment whether there was pharmacy treatment or self-medication, healthcare worker (HCW) inquiries about source of infection and whether the HCW was polite...
December 2, 2016: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/27913611/silent-somatotroph-tumour-revisited-from-a-study-of-80-patients-with-and-without-acromegaly-and-a-review-of-the-literature
#5
Laura Chinezu, Alexandre Vasiljevic, Jacqueline Trouillas, Marion Lapoirie, Emmanuel Jouanneau, Gérald Raverot
BACKGROUND: Silent somatotroph tumours are growth hormone (GH) immunoreactive (IR) pituitary tumours without clinical and biological signs of acromegaly. Their better characterisation is required to improve the diagnosis. MATERIALS AND METHODS: Twenty-one silent somatotroph tumours were compared to 59 somatotroph tumours with acromegaly. Tumours in each group were classified into GH and plurihormonal (GH/prolactin (PRL)/±thyroid-stimulating hormone (TSH)) and into densely granulated (DG) and sparsely granulated (SG) types...
February 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/27913252/sex-and-gender-differences-in-the-treatment-of-alzheimer-s-disease-a-systematic-review-of-randomized-controlled-trials
#6
Marco Canevelli, Federica Quarata, Francesca Remiddi, Flaminia Lucchini, Eleonora Lacorte, Nicola Vanacore, Giuseppe Bruno, Matteo Cesari
In recent years, epidemiological, clinical, and biological evidence has drawn the attention on the influence of sex and gender on Alzheimer's disease (AD). Nevertheless, not enough attention has been paid to their impact on treatment outcomes. The present study is aimed at systematically retrieve, review and discuss data coming from available randomized placebo-controlled trials (RCTs) on currently marketed treatments for AD (i.e., cholinesterase inhibitors [ChEIs] and memantine) in order to describe possible sex and gender differences in their efficacy, safety and tolerability...
November 29, 2016: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/27912908/childhood-sexual-abuse-and-substance-abuse-a-gender-paradox
#7
Lil Tonmyr, Margot Shields
We examine associations between childhood sexual abuse (CSA) and substance abuse, the role of mental health indicators as mediators in these associations and whether or not associations differ by gender. Data are from 14,063 respondents aged 18-76 years from the 2004-2005 Canadian Gender, Alcohol, and Culture: An International Study (GENACIS). Multiple logistic regression models were used to examine associations between CSA and substance abuse variables, controlling for socio-demographic factors. Odds were adjusted by indicators of mental health to assess if these variables mediated associations between CSA and substance abuse...
November 29, 2016: Child Abuse & Neglect
https://www.readbyqxmd.com/read/27912742/secular-trends-and-correlates-of-physical-activity-the-troms%C3%A3-study-1979-2008
#8
Bente Morseth, Bjarne K Jacobsen, Nina Emaus, Tom Wilsgaard, Lone Jørgensen
BACKGROUND: The aim was to describe secular trends in leisure time physical activity (LTPA) and work related physical activity (WPA) from 1979 to 2008. Additionally, we explored potential cross-sectional and longitudinal correlates of LTPA and WPA. METHODS: Data are collected from 34,898 individuals (49.7% men) aged >20 years who participated in at least one Tromsø Study survey between 1979 and 2008. In each survey, the participants completed a self-administered questionnaire and underwent physical examinations...
December 3, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27911960/application-of-latent-growth-modeling-to-identify-different-working-life-trajectories-the-case-of-the-spanish-workss-cohort
#9
Laura Serra, María Andrée López Gómez, Albert Sanchez-Niubo, George L Delclos, Fernando G Benavides
Objective The aim of this study was to describe the application of latent class growth analysis (LCGA) to identify different working life trajectories (WLT) using employed working time by year as a repeated measure. Methods Trajectories are estimated using LCGA, which considers all individuals within a trajectory to be homogeneous. The methodology was applied to a subsample of the Spanish WORKing life Social Security (WORKss) cohort, limited to persons born 1956-1965 (N=247 475). The number of days worked per year is used as a repeated measure across 32 time points (1981-2013)...
December 2, 2016: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/27911678/negative-religious-rhetoric-in-the-lives-of-black-cisgender-queer-emerging-adult-men-a-qualitative-analysis
#10
Ja'Nina J Garrett-Walker, Vanessa M Torres
Given the intersection of racial, religious, and sexual identities for Black queer populations, the current study examines sexuality related religious rhetoric. Twenty Black cisgender queer men were recruited to participate in a qualitative interview. Using thematic analysis, the research team identified four themes: negative religious rhetoric, personal consequences of negative religious rhetoric, social consequences of negative religious rhetoric, and growth from negative religious rhetoric. Participants explained the pervasiveness of negative religious rhetoric within their churches and family structures...
December 2, 2016: Journal of Homosexuality
https://www.readbyqxmd.com/read/27911671/exploring-first-sexual-intercourse-sexual-orientation-and-sexual-health-in-men
#11
Alexis Dewaele, Mieke Van Houtte, Katrien Symons, Ann Buysse
In this study the characteristics of the sexual debut of men who have sex with men (MSM) and men who have sex with women (MSW) age 35 or younger (N = 1,201) were compared with one another. We investigated whether these characteristics were associated with sexual health and behavior, and to what extent. Compared to MSW, MSM tended to be older when they had their first sexual intercourse; their first sex partner was older, they felt less ready, and they experienced more pain. We also found that they reported a higher number of lifetime sexual partners and less condom use compared to MSW...
December 2, 2016: Journal of Homosexuality
https://www.readbyqxmd.com/read/27911427/-modern-approach-to-early-diagnosis-and-pathogenetic-treatment-of-diabetic-retinopathy
#12
I V Vorob'eva
AIM: To improve the approach to pathogenetic treatment of diabetic retinopathy (DR) through early diagnosis and a new method for predicting disease progression. MATERIAL AND METHODS: The study enrolled 330 type 2 diabetes patients with DR (660 eyes), of whom women constituted 64.6%, men - 35.4%. The mean patient age was 62.3±2.3 years. Three groups were formed: the controls - 30 healthy volunteers (60 eyes) and 30 type 2 diabetes patients without ocular involvement (DR 0, 60 eyes); group 1 - 30 type 2 diabetes patients with DR I but no diabetic macular edema (DR I without DME, 60 eyes) that were treated with calcium dobesilate; group 2 - 240 type 2 diabetes patients, who had diabetic retinopathy of different stages (DR I, II, or III with DME, 480 eyes) and received laser retinal photocoagulation (LRP)...
2016: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/27911237/size-and-location-of-ruptured-intracranial-aneurysms-consecutive-series-of-1993-hospital-admitted-patients
#13
Miikka Korja, Riku Kivisaari, Behnam Rezai Jahromi, Hanna Lehto
OBJECTIVE Large consecutive series on the size and location of ruptured intracranial aneurysms (RIAs) are limited, and therefore it has been difficult to estimate population-wide effects of size-based treatment strategies of unruptured intracranial aneurysms. The authors' aim was to define the size and location of RIAs in patients diagnosed with subarachnoid hemorrhage due to aneurysm rupture in a high-volume academic center. METHODS Consecutive patients admitted to a large nonprofit academic hospital with saccular RIAs between 1995 and 2009 were identified, and the size, location, and multiplicity of RIAs were defined and reported by patient sex...
December 2, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27910722/post-exposure-prophylaxis-awareness-and-use-among-men-who-have-sex-with-men-in-london-who-use-geosocial-networking-smartphone-applications
#14
William C Goedel, Daniel Hagen, Perry N Halkitis, Richard E Greene, Marybec Griffin-Tomas, Forrest A Brooks, DeMarc Hickson, Dustin T Duncan
The number of new HIV infections continues to be on the rise in many high-income countries, most notably among men who have sex with men (MSM). Despite recent attention to the use of antiretroviral medications as pre-exposure prophylaxis (PrEP) among MSM, considerably less research has been devoted to examining the awareness and use of post-exposure prophylaxis (PEP). Based on a convenience sample of 179 self-reported HIV-uninfected MSM using a geosocial-networking smartphone application, this study is among the first to examine the awareness and use of PEP and their demographic and behavioral correlates among MSM in London...
December 2, 2016: AIDS Care
https://www.readbyqxmd.com/read/27910255/dysphagia-is-associated-with-functional-decline-during-acute-care-hospitalization-of-older-patients
#15
Haruyo Matsuo, Yoshihiro Yoshimura, Naoki Ishizaki, Tsuyoshi Ueno
AIM: Physical function is considered to be associated with dysphagia: however, there is little data regarding the association between dysphagia and functional decline during hospitalization among older patients. The aim of the present study was to investigate the prevalence of dysphagia, and the association between dysphagia and functional status during hospitalization in older acute-care patients. METHODS: A total of 103 older patients without present or prior history of diseases that could directly impair swallowing and cause dysphagia (45 men and 58 women; mean age 80...
December 1, 2016: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/27909906/obesity-and-prostate-cancer
#16
Yin Cao, Edward Giovannucci
Prostate cancer is a complex, heterogeneous disease. Factors related to detection, particularly PSA screening, further increase heterogeneity in the manifestation of the disease. It is thus not possible to provide a simple summary of the relationship between obesity and prostate cancer. Findings on obesity, often defined using body mass index (BMI), and total prostate cancer risk have been mixed; however, obesity is relatively consistently associated with a higher risk of aggressive prostate cancer, with aggressiveness defined in various ways (e...
2016: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/27909903/obesity-and-kidney-cancer
#17
Kathryn M Wilson, Eunyoung Cho
Renal cell cancer (RCC) is the major type of kidney cancer with increasing incidence. Obesity is one of the well-established risk factors for RCC. Meta-analyses including multiple cohort and case-control studies have found a consistent positive association between obesity and RCC. The association appeared to be independent of other RCC risk factors including hypertension and has been often stronger in women, although a positive association has also been observed in men. Obesity has been largely measured as body mass index (BMI)...
2016: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/27909900/obesity-and-colorectal-cancer
#18
Carmen Jochem, Michael Leitzmann
There is strong evidence that modifiable lifestyle factors such as obesity play a key role in colorectal carcinogenesis. Epidemiologic data have consistently reported a positive association between obesity and colorectal cancer. The relative risk associated with general obesity (as assessed by BMI) is higher in men than in women and for cancer of the colon than for cancer of the rectum. Abdominal obesity (as assessed by waist circumference (WC) or waist-to-hip ratio) is associated with an increased risk of colorectal cancer in both sexes, with stronger associations for cancer of the colon than for cancer of the rectum...
2016: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/27909451/gender-differences-in-somatic-symptoms-and-current-suicidal-risk-in-outpatients-with-major-depressive-disorder
#19
Hong Jin Jeon, Jong-Min Woo, Hyo-Jin Kim, Maurizio Fava, David Mischoulon, Seong Jin Cho, Sung Man Chang, Doo-Heum Park, Jong Woo Kim, Ikki Yoo, Jung-Yoon Heo, Jin Pyo Hong
OBJECTIVE: Although somatic symptoms are common complaints of patients with major depressive disorder (MDD), their associations with suicide are still unclear. METHODS: A total of 811 MDD outpatients of aged between 18 to 64 years were enrolled nationwide in Korea with the suicidality module of the Mini-International Neuropsychiatric Interview (MINI) and the Depression and Somatic Symptom Scale (DSSS). RESULTS: On stepwise regression analysis, current suicidality scores were most strongly associated with chest pain in men, and neck or shoulder pain in women...
November 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27909142/disease-activity-and-increased-risk-of-cardiovascular-death-among-patients-with-psoriatic-arthritis
#20
Kristina Juneblad, Solbritt Rantapää-Dahlqvist, Gerd-Marie Alenius
OBJECTIVE: Recent studies indicate increased cardiovascular (CV) morbidity and mortality in patients with psoriatic arthritis (PsA), but results are inconsistent. This prompted our investigation of the mortality rate, cause of death, and incidence of acute CV events in patients from northern Sweden with PsA. METHODS: Patients with established PsA (464) were included. To calculate standardized mortality ratio (SMR) and standardized incidence ratio (SIR) for CV events, data were extracted from the National Causes of Death Register and the National Inpatient Care Register in Sweden, and compared with the general population...
December 2016: Journal of Rheumatology
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