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https://www.readbyqxmd.com/read/28644041/identifying-the-functional-groups-and-the-influence-of-synthetic-chelators-on-cd-availability-and-microbial-biomass-carbon-in-cd-contaminated-soil
#1
Muhammad Afzal Chhajro, Qingling Fu, Muhammad Shaaban, Muhammad Shahid Rizwan, Jun Zhu, Abdus Salam, Kashif Ali Kubar, Saqib Bashir, Hongqing Hu, Ghulam Murtaza Jamro
Synthetic chelators play an important role in boosting the microbial biomass carbon (MBC), dissolved organic carbon (DOC) and heavy metal solubility in a contaminated soil towards a sustainability of environment for agricultural crops. Castor was selected as a potential cadmium (Cd) accumulator in different levels of Cd (-Cd and +Cd) contamination with using three chelating agents, ethylenediamine tetraacetic acid (H4EDTA), nitriloacetic acid (H3 NTA) and NH4 citrate (ammonium citrate) were added to soil at rates of 10, 15 and 25 mmol in 5 kg of soil per pot...
June 23, 2017: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/28640246/gwas-signals-revisited-using-human-knockouts
#2
Sateesh Maddirevula, Fatema AlZahrani, Shams Anazi, Mariam Almureikhi, Tawfeg Ben-Omran, Ghada M H Abdel-Salam, Mais Hashem, Niema Ibrahim, Firdous M Abdulwahab, Neama Meriki, Fahad A Bashiri, Meow-Keong Thong, Premala Muthukumarasamy, Rifhan Azwani Mazlan, Ranad Shaheen, Fowzan S Alkuraya
PurposeGenome-wide association studies (GWAS) have been instrumental to our understanding of the genetic risk determinants of complex traits. A common challenge in GWAS is the interpretation of signals, which are usually attributed to the genes closest to the polymorphic markers that display the strongest statistical association. Naturally occurring complete loss of function (knockout) of these genes in humans can inform GWAS interpretation by unmasking their deficiency state in a clinical context.MethodsWe exploited the unique population structure of Saudi Arabia to identify novel knockout events in genes previously highlighted in GWAS using combined autozygome/exome analysis...
June 22, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/28636506/incidence-and-predictors-of-atrial-fibrillation-after-coronary-artery-bypass-surgery-detection-by-event-loop-recorder-monitoring-from-a-contemporary-multicentre-cohort
#3
Zainab Abdel-Salam, Wail Nammas
Background Atrial fibrillation (AF) is a frequent complication after cardiac surgery. We explored the incidence and predictors of post-operative AF at 30-day follow-up in an unselected multi-centre cohort of patients undergoing elective coronary artery bypass grafting (CABG) in contemporary practice. Methods and results We enrolled 740 consecutive patients scheduled for elective CABG with or without valve surgery. Cardiac rhythm was continuously monitored for 15 days after surgery by an ambulatory event loop recorder...
March 21, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28630852/adult-traumatic-inferior-hip-dislocation-rare-case-ended-with-open-reduction
#4
Salam Ismael, J Vora, P Thomas
INTRODUCTION: An inferior hip dislocation also called luxatio erecta femoris is a rare type of hip dislocation that is not widely reported in literature. Only 12 cases are reported in British literature. CASE REPORT: This article reports a 17-year-old male involved in a road traffic accident, sustaining inferior hip dislocation. Following resuscitation, computed tomography confirmed the clinical diagnoses. Several attempts to perform a closed reduction of the hip under sedation and general anesthesia failed to reduce the dislocation...
January 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28625341/efficacy-and-toxicity-of-metronomic-chemotherapy-in-metastatic-breast-cancer-egyptian-experience
#5
Marwa Mahmoud Hussein, Rabab Mohamed Gaafar, Ahmed Mostafa Abdel-Warith, Wafaa Abdallah Ahmed, Nasr Mohamed Ali Allahloubi, Salem Eid Salem, Ibrahem Mohamed Abdel-Salam
BACKGROUND: Metronomic chemotherapy (MC) has shown efficacy in patients with metastatic breast cancer (MBC). We therefore tested the efficacy and toxicity of MC in pretreated MBC. PATIENTS AND METHODS: This prospective phase II study included 50 patients with heavily pretreated MBC who received MC in the form of continuous oral cyclophosphamide 50 mg/day and oral methotrexate 2.5 mg twice per day on days 1 and 2 every week. The primary end point was progression-free survival (PFS), whereas the secondary end points were response rate, overall survival (OS), and safety...
May 8, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28623443/autolyse-the-cell-in-order-to-save-it-inducing-then-blocking-autolysis-as-a-strategy-for-delaying-cell-death-in-the-probiotic-lactobacillus-reuteri
#6
Tahl Zimmerman, Rabin Gyawali, Salam Ibrahim
OBJECTIVE: To examine whether choline and its derivatives can be used to preserve viable cells of Lactobacillus reuteri in autolytic models. RESULTS: A phosphate-induced autolytic model in de Man, Rogosa and Sharpe medium (MRS) was used. Viable cell counts were determined by plated on MRS-agar. Choline and hemicholinium-3 (HC-3) significantly blocked autolysis of L. reuteri at 360 mM and 4 mM, respectively. Viable cell counts corroborated these observations. Importantly, autolytically induced cells treated with choline and hemicholinium-3 were significantly more viable then even non-induced cells...
June 16, 2017: Biotechnology Letters
https://www.readbyqxmd.com/read/28605330/effect-of-antihypertensive-drug-treatment-on-oxidative-stress-markers-in-heart-of-spontaneously-hypertensive-rat-models
#7
Nik Syamimi Nik Yusoff, Zulkarnain Mustapha, Sharifah Emilia Tuan Sharif, Chandran Govindasamy, Kuttulebbai Nainamohamed Salam Sirajudeen
Oxidative stress has been suggested to play a role in hypertension- and hypertension-induced organ damage. The effect of antihypertensive drug treatments on oxidative stress markers has not been well assessed. Therefore, in this study we investigated the effect of enalapril on oxidative stress markers in hearts of hypertensive rat models such as spontaneously hypertensive rats (SHR) and SHRs administered N-nitro-L-arginine methyl ester (SHR+L-NAME rats). Male rats were divided into four groups: SHRs, SHR+enalapril (SHR-E) rats, SHR+L-NAME rats, SHR+enalapril+L-NAME (SHRE+L-NAME) rats...
2017: Journal of Environmental Pathology, Toxicology and Oncology
https://www.readbyqxmd.com/read/28600663/serum-hepcidin-as-a-diagnostic-marker-of-severe-iron-overload-in-beta-thalassemia-major
#8
Ahmed Maher Kaddah, Amina Abdel-Salam, Marwa Salah Farhan, Reham Ragab
OBJECTIVES: To investigate potential usefulness of serum hepcidin in the diagnosis of iron overload in children with β-thalassemia. METHODS: A study was conducted on 30 thalassemia major (TM), 30 thalassemia intermedia (TI) and 60 healthy children as controls. Serum hepcidin was measured by Human Hepcidin, ELISA Kit. RESULTS: β-thalassemia patients had a higher serum hepcidin compared to the controls (p < 0.001). TM group had higher hepcidin and ferritin compared to the TI group (p = 0...
June 10, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28590451/environmental-factors-associated-with-type-1-diabetes-development-a-case-control-study-in-egypt
#9
Nabil J Awadalla, Amal A Hegazy, Manal Abd El-Salam, Marwa Elhady
Uncertainty still exists regarding the role of some environmental risk in the development of type 1 diabetes mellitus (T1DM) both globally and in Egypt. The objective here was to explore the potential environmental risk factors associated with the development of T1DM among children in Egypt. A case-controlled study of 204 T1DM children and an equal number of age and sex-matched controls was conducted in Assiut, Egypt. Data regarding the parental, gestational, neonatal, and childhood possible risk factors for T1DM were evaluated...
June 7, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28587199/impact-of-sweet-potato-starch-based-nanocomposite-films-activated-with-thyme-essential-oil-on-the-shelf-life-of-baby-spinach-leaves
#10
Aseel Issa, Salam A Ibrahim, Reza Tahergorabi
Salmonella Typhimurium (S. Typhi) and Escherichia coli (E. coli) have been responsible for an increasing number of outbreaks linked to fresh produce, such as baby spinach leaves, in the last two decades. More recently, antimicrobial biodegradable packaging systems have been attracting much attention in the food packaging industry as eco-friendly alternatives to conventional plastic packaging. The objective of this study was to evaluate the effect of antibacterial nanocomposite films on inoculated spinach leaves and on the sensory properties of these leaves during eight days of refrigerated storage...
June 3, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28586604/orbital-involvement-in-sinonasal-diseases
#11
Zia-Us-Salam Qazi, Sarfraz Latif, Sadia Maqsood Awan
OBJECTIVE: Orbital involvement in sinonasal diseases can present as proptosis, ophthalmoplegia or even as blindness due to optic nerve damage. There are a number of sinonasal diseases which can involve eyes. The purpose of this study was to enlist diagnoses of all the patients with sinonasal disease, in which orbit was also involved unilaterally or bilaterally and to analyse the management strategy and final outcome in all the cases. METHODS: Hundred consecutive patients having orbital symptoms along with sinonasal complaints that presented in ENT department of Shaikh Zayed federal postgraduate medical institute were included in our prospective study...
October 2016: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28585047/aquichromatium-aeriopus-gen-nov-sp-nov-a-non-phototrophic-aerobic-chemoheterotrophic-bacterium-and-proposal-of-aquichromatiaceae-fam-nov-in-the-order-chromatiales
#12
Liqiang Yang, Lili Tang, Lan Liu, Nimaichand Salam, Wen-Jun Li, Yongyu Zhang
A gram-staining negative, non-motile, aerobic chemoheterotrophic, ovoid or short rod-shaped bacterium, designated as J89(T), was isolated from a seawater sample collected from the coast of Yellow Sea in Qingdao, China. The strain grew at salinities of 1.0-6.0% (w/v) NaCl (optimum, 3.0%). Growth occurred at pH 6.0-9.0 (optimum, pH 7.0) and at 10-35 °C (optimum, 25-30 °C). The genomic DNA G+C content was determined to be 59.3 mol%. Q-8 was detected as the respiratory quinone. The major fatty acids (>10%) were summed feature 3 (C16:1 ω7c and/or C16:1 ω6c), summed feature 8 (C18:1 ω7c and/or C18:1 ω6c), and C16:0...
June 6, 2017: Current Microbiology
https://www.readbyqxmd.com/read/28584598/impact-of-aberrant-myeloid-antigen-expression-on-outcomes-of-patients-with-t-cell-acute-lymphoblastic-leukemia
#13
Mohamed Al-Zaabi, Murtadha Al-Khabori, Naglaa Fawaz, Sulayma Al-Lamki, Arwa Al-Riyami, Mohammed Al-Huneini, Muhanna Al-Muslahi, Salam Alkindi
OBJECTIVES: To evaluate the impact of myeloid antigen expression on complete remission (CR), event-free survival (EFS), and overall survival (OS) in patients with T-cell acute lymphoblastic leukemia (T-ALL) treated with intensive chemotherapy. METHODS: We retrospectively reviewed consecutive patients diagnosed with T-ALL and treated in Sultan Qaboos University Hospital and Royal Hospital in Oman between 2004 and 2010. The diagnosis of T-ALL was established using French-American-British classification or World Health Organization criteria...
May 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28584013/efficacy-and-safety-of-quarter-dose-blood-pressure-lowering-agents-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#14
Alexander Bennett, Clara K Chow, Michael Chou, Hakim-Moulay Dehbi, Ruth Webster, Abdul Salam, Anushka Patel, Bruce Neal, David Peiris, Jay Thakkar, John Chalmers, Mark Nelson, Christopher Reid, Graham S Hillis, Mark Woodward, Sarah Hilmer, Tim Usherwood, Simon Thom, Anthony Rodgers
There is a critical need for blood pressure-lowering strategies that have greater efficacy and minimal side effects. Low-dose combinations hold promise in this regard, but there are few data on very-low-dose therapy. We, therefore, conducted a systematic review and meta-analysis of randomized controlled trials with at least one quarter-dose and one placebo and standard-dose monotherapy arm. A search was conducted of Medline, Embase, Cochrane Registry, Food and Drug Administration, and European Medicinal Agency websites...
July 2017: Hypertension
https://www.readbyqxmd.com/read/28580799/flavonoids-of-alcea-rosea-l-and-their-immune-stimulant-antioxidant-and-cytotoxic-activities-on-hepatocellular-carcinoma-hepg-2-cell-line
#15
Nabil A Abdel-Salam, Nabila M Ghazy, Shaimaa M Sallam, Mohamed M Radwan, Amira S Wanas, Mahmoud A ElSohly, Maha A El-Demellawy, Nevin M Abdel-Rahman, Sonia Piacente, Mary L Shenouda
Alcea rosea L. is widely cultivated in gardens of Egypt as an ornamental plant and it has a great history of folkloric medicinal uses. In the present work, phytochemical investigation of the alcoholic extract of the flowers of A. rosea L. led to the isolation of six flavonoids (1-6). Dihydrokaempferol-4'-O-β-d-glucopyranoside (1), dihydrokaempferol (2), kaempferol-3-O-[6″-(E-coumaroyl)]-β-d-glucopyranoside (3), kaempferol-3-O-β-d-glucopyranoside (4), Apigenin (5) and kaempferol-3-O-α-l-rhamnopyranosyl-(1'″→6″)-β-d-glucopyranoside (6)...
June 5, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28579508/decompressive-hemicraniectomy-for-malignant-middle-cerebral-artery-stroke-south-asian-experience
#16
Saadat Kamran, Naveed Akhtar, Abdul Salam, Ayman Alboudi, Hiba Rashid, Kainat Kamran, Rabia Ali Khan, Mohsin Khalid Mirza, Arsalan Ahmed, Ahmed M A Own, Sohail Al Rukun, Jihad Inshasi, Dirk Deleu, Ghanim Al Sulaiti, Ashfaq Shuaib
BACKGROUND: The randomized trials showed improved outcome and reduced mortality in malignant middle cerebral artery (MMCA) undergoing Decompressive hemicraniectomy (DHC) within 48 hours of stroke onset. Despite high prevalence of stroke, especially in younger individuals, high and short-term mortality from stroke in South Asian and Middle East, there is little published data on DHC in patients with MMCA stroke. METHODS: This is a retrospective, multicenter cross-sectional study to measure outcome following DHC using the modified Rankin Scale (mRS) and dichotomized as favorable (mRS ≤ 4) or unfavorable (mRS > 4), at 3 months...
June 1, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28567624/properties-environmental-fate-and-biodegradation-of-carbazole
#17
REVIEW
Lateef B Salam, Mathew O Ilori, Olukayode O Amund
The last two decades had witnessed extensive investigation on bacterial degradation of carbazole, an N-heterocyclic aromatic hydrocarbon. Specifically, previous studies have reported the primary importance of angular dioxygenation, a novel type of oxygenation reaction, which facilitates mineralization of carbazole to intermediates of the TCA cycle. Proteobacteria and Actinobacteria are the predominant bacterial phyla implicated in this novel mode of dioxygenation, while anthranilic acid and catechol are the signature metabolites...
June 2017: 3 Biotech
https://www.readbyqxmd.com/read/28566791/reverse-distal-femoral-locking-compression-plate-a-salvage-option-in-nonunion-of-proximal-femoral-fractures
#18
Yasir Salam Siddiqui, Mohd Khalid Anwar Sherwani
No abstract text is available yet for this article.
May 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28561324/curcumin-ameliorates-kidney-function-and-oxidative-stress-in-experimental-chronic-kidney-disease
#19
Badreldin H Ali, Suhail Al-Salam, Yousuf Al Suleimani, Jamila Al Kalbani, Shadia Al Bahlani, Mohammed Ashique, Priyadarsini Manoj, Buthaina Al Zhili, Nadia Al Abri, Heba T Naser, Javed Yasin, Abderrahim Nemmar, Mohamed Al Za'abi, Christina Hartmann, Nicole Schupp
Chronic kidney disease (CKD) is known to involve inflammation, oxidative stress and apoptosis. Here, we investigated the impact of curcumin (diferuloyl methane, a phenolic turmeric pigment), which has strong anti-oxidant, anti-inflammatory and anti-apoptotic activities on kidney structure and function in rats with adenine-induced CKD. Rats were treated for 5 weeks with adenine to induce CKD-like renal damage and combined with three doses of curcumin. Markers of kidney function and oxidative stress were quantified in plasma, urine, renal homogenates and on kidney tissue...
May 31, 2017: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28555096/role-of-anterior-cingulate-cortex-in-instrumental-learning-blockade-of-dopamine-d1-receptors-suppresses-overt-but-not-covert-learning
#20
Mayada Aly-Mahmoud, Pascal Carlier, Sherine A Salam, Mariam Houari Selmani, Marie Z Moftah, Monique Esclapez, Driss Boussaoud
HIGHLIGHTS Blockade of dopamine D1 receptors in ACC suppressed instrumental learning when overt responding was required.Covert learning through observation was not impaired.After treatment with a dopamine antagonist, instrumental learning recovered but not the rat's pretreatment level of effort tolerance.ACC dopamine is not necessary for acquisition of task-relevant cues during learning, but regulates energy expenditure and effort based decision. Dopamine activity in anterior cingulate cortex (ACC) is essential for various aspects of instrumental behavior, including learning and effort based decision making...
2017: Frontiers in Behavioral Neuroscience
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