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https://www.readbyqxmd.com/read/29786647/health-disparities-score-composite-of-youth-and-parent-dyads-from-an-obesity-prevention-intervention-icook-4-h
#1
Melissa D Olfert, Makenzie L Barr, Rebecca L Hagedorn, Lisa Franzen-Castle, Sarah E Colby, Kendra K Kattelmann, Adrienne A White
iCook 4-H is a lifestyle intervention to improve diet, physical activity and mealtime behavior. Control and treatment dyads (adult primary meal preparer and a 9⁻10-year-old youth) completed surveys at baseline and 4, 12, and 24 months. A Health Disparity (HD) score composite was developed utilizing a series of 12 questions (maximum score = 12 with a higher score indicating a more severe health disparity). Questions came from the USDA short form U.S. Household Food Security Survey (5), participation in food assistance programs (1), food behavior (2), level of adult education completed (1), marital status (1), and race (1 adult and 1 child)...
May 22, 2018: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/29778325/tranexamic-acid-for-hyperacute-primary-intracerebral-haemorrhage-tich-2-an-international-randomised-placebo-controlled-phase-3-superiority-trial
#2
Nikola Sprigg, Katie Flaherty, Jason P Appleton, Rustam Al-Shahi Salman, Daniel Bereczki, Maia Beridze, Hanne Christensen, Alfonso Ciccone, Ronan Collins, Anna Czlonkowska, Robert A Dineen, Lelia Duley, Juan Jose Egea-Guerrero, Timothy J England, Kailash Krishnan, Ann Charlotte Laska, Zhe Kang Law, Serefnur Ozturk, Stuart J Pocock, Ian Roberts, Thompson G Robinson, Christine Roffe, David Seiffge, Polly Scutt, Jegan Thanabalan, David Werring, David Whynes, Philip M Bath
BACKGROUND: Tranexamic acid can prevent death due to bleeding after trauma and post-partum haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma expansion and improves outcome in adults with stroke due to intracerebral haemorrhage. METHODS: We did an international, randomised placebo-controlled trial in adults with intracerebral haemorrhage from acute stroke units at 124 hospital sites in 12 countries. Participants were randomly assigned (1:1) to receive 1 g intravenous tranexamic acid bolus followed by an 8 h infusion of 1 g tranexamic acid or a matching placebo, within 8 h of symptom onset...
May 15, 2018: Lancet
https://www.readbyqxmd.com/read/29656662/beneficial-effects-of-salvia-miltiorrhiza-in-the-healing-of-burn-wounds-an-experimental-study-in-rats
#3
Fatih Irmak, Sevgi Kurt Yazar, Serhat Selami Şirvan, Merdan Serin, Ayşim Özağarı, Ayşin Karasoy Yeşilada
INTRODUCTION: Burn healing is a complicated process and very few treatments can positively alter its effects. The aim of this study was to investigate the effects Salvia miltiorrhiza (SM -Danshen), a traditional Chinese medicine, on burn wound healing. MATERIAL AND METHODS: Twenty rats were included in this study and divided into two groups. 3 × 2 cm wide burn areas were created in the dorsal skin of all the animals with thermal contact. Intraoral 1 ml/day saline and 1 g/kg/day SM were given in control and experiment groups, respectively...
April 14, 2018: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/29582656/investigating-and-modeling-the-transport-of-the-new-horizon-reduced-graphene-oxide-metal-oxide-nanohybrids-in-water-saturated-porous-media
#4
Dengjun Wang, Yan Jin, Chang Min Park, Jiyong Heo, Xue Bai, Nirupam Aich, Chunming Su
Little is known about the fate and transport of the 'new-horizon' multifunctional nanohybrids in the environment. Saturated sand-packed column experiments (n=66) were therefore performed to investigate the transport and retention of reduced graphene oxide (RGO)-metal oxide (Fe3O4, TiO2, and ZnO) nanohybrids under environmentally-relevant conditions (mono- and di-valent electrolytes and natural organic matter). Classical colloid science principles (Derjaguin-Landau-Verwey-Overbeek (DLVO) theory and colloid filtration theory (CFT)) and mathematical models based on the one-dimensional convection-dispersion equation were employed to describe and predict the mobility of RGO-Fe3O4, RGO-TiO2, and RGO-ZnO nanohybrids in porous media...
March 27, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29541464/comparison-of-surgical-outcomes-and-complications-between-the-harmonic-focus-and-conventional-surgery-for-open-thyroidectomy
#5
Hideki Maeda, Goro Kutomi, Fukino Satomi, Hiroaki Shima, Mitsuru Mori, Ichiro Takemasa
The aim of the present study was to evaluate the potential advantages of the ultrasonic scalpel compared with the conventional technique in thyroid surgery. Patients with resectable thyroid cancer and Basedow's disease were assigned to ultrasonic scalpel or conventional technique (knot-tying and electrocoagulation). The present study used the Harmonic FOCUS® (HF) as an ultrasonic scalpel. Between February 2013 and May 2016, 45 patients were enrolled into the study. Duration of the surgery was significantly decreased in the HF group compared with the conventional surgery (CS) group (median 142 vs...
April 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29432441/fas-promoter-polymorphisms-and-serum-sfas-level-are-associated-with-increased-risk-of-nerve-damage-in-bangladeshi-patients-with-guillain-barr%C3%A3-syndrome
#6
Zhahirul Islam, Israt Jahan, Rijwan U Ahammad, Mohammad Shahnaij, Shamsun Nahar, Quazi D Mohammad
Guillain-Barré syndrome (GBS) is an autoimmune disorder of the peripheral nervous system triggered by molecular mimicry between pathogen lipopolysaccharides and host nerve gangliosides. Polymorphisms in the Fas receptor (FAS) and Fas ligand (FASL) genes may potentially alter the elimination of autoreactive immune cells and affect disease susceptibility or disease severity in GBS. We detected single nucleotide polymorphisms (SNPs) in FAS (-1377G/A and -670A/G) and FASL (-843C/T) in a prospective cohort of 300 patients with GBS and 300 healthy controls from the Bangladeshi population...
2018: PloS One
https://www.readbyqxmd.com/read/29375117/tolvaptan-improves-prognosis-in-responders-with-acute-decompensated-heart-failure-by-reducing-the-dose-of-loop-diuretics
#7
COMPARATIVE STUDY
Makiko Nakamura, Osahiko Sunagawa, Koichiro Kinugawa
It is unknown whether a response to tolvaptan (TLV) is related to prognosis in patients with acute decompensated heart failure (ADHF). We selected 25 patients as responders by their urinary response to TLV and by reduction of loop diuretics from 37 consecutive ADHF patients treated with TLV. As a control group, we selected 25 patients from 100 consecutive ADHF patients who were not treated with TLV by propensity score matching for age, serum sodium level, serum creatinine level, plasma B-type natriuretic peptide (BNP) level, systolic blood pressure, heart rate, and dose of loop diuretics...
2018: International Heart Journal
https://www.readbyqxmd.com/read/29354867/short-and-long-term-outcomes-of-surgical-management-of-peptic-ulcer-complications-in-the-era-of-proton-pump-inhibitors
#8
Rabea Hasadia, Yael Kopelman, Oded Olsha, Ricardo Alfici, Itamar Ashkenazi
PURPOSE: We evaluated the short-term and long-term outcomes of emergency operations for peptic ulcer (PUD) complications in a period of time in which the need for surgery is infrequent. METHODS: Retrospective review of operated patients (2007-2015) in one medical center. RESULTS: 81 patients were included (8.9 patients/year): 70 (86.4%) male; 11 (13.6%) female. Indications for operation were hemorrhage in 18 (22.2%), perforation in 62 (76...
January 22, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29327120/readmission-and-reoperation-after-midurethral-sling
#9
Erik D Hokenstad, Amy E Glasgow, Elizabeth B Habermann, John A Occhino
INTRODUCTION AND HYPOTHESIS: We aimed to determine the rate of readmission and reoperation for patients undergoing midurethral sling (MUS) placement for stress urinary incontinence (SUI). METHODS: The American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database was queried to identify all isolated MUS placed from 2012 through 2015 using the Current Procedural Terminology 4 (CPT-4) code for MUS with or without cystoscopy (57,288 ± 52,000)...
January 11, 2018: International Urogynecology Journal
https://www.readbyqxmd.com/read/29316054/influence-of-body-mass-index-on-induction-of-labor-a-historical-cohort-study
#10
Ulf Dammer, Roswitha Bogner, Christel Weiss, Florian Faschingbauer, Jutta Pretscher, Matthias W Beckmann, Marc Sütterlin, Sven Kehl
AIM: We aimed to determine the influence of body mass index (BMI) on induction of labor. METHODS: In this historical multicenter cohort study, 2122 labor inductions were analyzed. Women were divided into four groups according to their body mass index (BMI): BMI < 30 (normal group [NG]), 30 ≤ BMI < 35 (group 1 [G1]), 35 ≤ BMI < 40 (group 2 [G2]), and BMI ≥ 40 (group 3 [G3]). The primary outcome measure was the induction-to-delivery interval...
April 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29310709/the-effect-of-patent-dictyocaulus-viviparus-re-infections-on-individual-milk-yield-and-milk-quality-in-pastured-dairy-cows-and-correlation-with-clinical-signs
#11
Katharina May, Kerstin Brügemann, Sven König, Christina Strube
BACKGROUND: Infections with the bovine lungworm Dictyocaulus viviparus might lead to reduced milk production and detrimental impacts on milk quality resulting in considerable economic losses in dairy farming. METHODS: In the presented field study, 1988 faecal samples were collected from 1166 Black and White dairy cows allocated in 17 small and medium-sized German grassland farms. Faecal samples were collected in summer and autumn 2015 to assess D. viviparus larvae excretion...
January 8, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29302799/early-abnormal-transient-hyperemic-response-test-can-predict-delayed-ischemic-neurologic-deficit-in-subarachnoid-hemorrhage
#12
Hosam Al-Jehani, Mark Angle, Judith Marcoux, Jeanne Teitelbaum
BACKGROUND: Early detection of vasospasm is crucial to prevent significant delayed ischemic neurological deficit post subarachnoid hemorrhage. The standard methods of detection, including cerebral angiogram and computed tomography are invasive and not safe to be repeated, as is very often indicated clinically. Transient hyperemic response test has been previously used to predict autoregulation failure in traumatic brain injury and subarachnoid hemorrhage. AIMS: We investigate the usability of transient hyperemic response test as a predictor of clinical vasospasm in a cohort of patients with aneurismal subarachnoid hemorrhage...
January 4, 2018: Critical Ultrasound Journal
https://www.readbyqxmd.com/read/29239264/clinical-significance-of-plasma-presepsin-levels-in-patients-with-systemic-lupus-erythematosus
#13
Shun Tanimura, Yuichiro Fujieda, Michihiro Kono, Yuhei Shibata, Ryo Hisada, Eri Sugawara, Hiroyuki Nakamura, Kazumasa Ohmura, Sanae Shimamura, Asako Mitani, Haruki Shida, Toshiyuki Watanabe, Masaru Kato, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Shinsuke Yasuda, Chikara Shimizu, Tatsuya Atsumi
OBJECTIVES: Presepsin (PSEP: soluble CD14 subtype) is produced from bacteria-stimulated monocytes or neutrophils, thus recognized as a biomarker of sepsis. Aberrant functions in monocyte or neutrophils are increasingly recognized in systemic lupus erythematosus (SLE). We investigated whether plasma PSEP reflects disease activity in patients with SLE. METHODS: This retrospective study comprised 35 patients with SLE and 72 with non-SLE autoimmune diseases who visited our facility during the period from August 2012 to September 2015...
December 14, 2017: Modern Rheumatology
https://www.readbyqxmd.com/read/29108792/comparison-of-the-primary-stability-of-a-porous-coated-acetabular-revision-cup-with-a-standard-cup
#14
Nicholas A Beckmann, Sebastian Jaeger, Maciej B Janoszka, Matthias C Klotz, Thomas Bruckner, Rudi G Bitsch
BACKGROUND: The number of revision hip arthroplasty procedures has been increasing substantially, with the acetabular component requiring component revision in over half of the cases. New porous implant designs attempt to improve outcomes due to improved osseointegration; however, sufficient primary stability is paramount for good osseointegration. METHODS: We compared 2 revision cups of the same geometry, yet different surface properties in an in vitro scenario: a porous titanium surface and a conventional sintered-bead titanium surface...
February 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29080252/clinical-evaluation-of-tavocept-to-decrease-diuresis-time-and-volume-in-dogs-with-bladder-cancer-receiving-cisplatin
#15
C J Henry, B K Flesner, S A Bechtel, J N Bryan, D J Tate, K A Selting, J C Lattimer, M E Bryan, L Grubb, F Hausheer
BACKGROUND: Transitional cell carcinoma is the most common bladder cancer of dogs. Cisplatin combined with piroxicam provides superior response rates, but unacceptable rates of nephrotoxicity. Tavocept is a chemoprotectant that has mitigated cisplatin toxicity and decreased the required infusion/diuresis volume in clinical trials in humans. HYPOTHESIS/OBJECTIVES: We hypothesized that Tavocept would decrease diuresis volume and time and facilitate safe administration of a cisplatin/piroxicam protocol to dogs with bladder cancer...
January 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29067083/the-long-term-prognosis-of-epilepsy-patients-with-medically-treated-over-a-period-of-eight-years-in-turkey
#16
Pelin Duman, Asuman Orhan Varoglu, Esra Kurum
OBJECTIVE: The aim of this study was to investigate the effect of demographic and clinical characteristics on temporal changes in seizure control and frequency in medically treated epilepsy patients to guide treatment modalities. METHODS: We retrospectively analyzed the association between clinical and demographic characteristics and seizure frequency in 1329 epilepsy patients who were followed up at an outpatient clinic for one to eight years, 2008-2015.. RESULTS: Younger age at first seizure ( p = 0...
July 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29052094/severe-physical-complications-among-survivors-of-stevens-johnson-syndrome-and-toxic-epidermal-necrolysis
#17
Cristina Olteanu, Neil H Shear, Hall F Chew, Rena Hashimoto, Raed Alhusayen, Sonia Whyte-Croasdaile, Yaron Finkelstein, Marjorie Burnett, Michael Ziv, Shachar Sade, Marc G Jeschke, Roni P Dodiuk-Gad
INTRODUCTION: Few studies have reported the physical complications among Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) survivors. OBJECTIVE: The aim of this study was to comprehensively characterize the physical complications among SJS/TEN survivors and to learn about patients' perspectives of surviving SJS/TEN. METHODS: SJS/TEN survivors older than 18 years of age were assessed by different methods: a medical interview; a questionnaire assessing patients' perspectives; thorough skin, oral mucous membrane, and ophthalmic examinations; and a retrospective assessment of medical records...
March 2018: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/29045029/the-immunosuppressant-brasilicardin-determination-of-the-biosynthetic-gene-cluster-in-the-heterologous-host-amycolatopsis-japonicum
#18
Paul N Schwarz, Anina Buchmann, Luisa Roller, Andreas Kulik, Harald Gross, Wolfgang Wohlleben, Evi Stegmann
Nocardia terpenica IFM 0406 is the producer of the immunosuppressants brasilicardins A-D. Brasilicardin is a promising compound because of its unique mode of action and its higher potency and reduced toxicity compared to today's standard drugs. However, production of brasilicardin is so far hampered as Nocardia terpenica IFM 0406 synthesizes brasilicardin in only low amounts and represents a human pathogen (biosafety level 2 BSL2). In order to achieve a safe and high yield production of brasilicardin A (BraA), the authors heterologously express the brasilicardin gene cluster in the nocardioform actinomycete Amycolatopsis japonicum (A...
February 2018: Biotechnology Journal
https://www.readbyqxmd.com/read/29033041/short-term-venoarterial-extracorporeal-membrane-oxygenation-for-massive-endobronchial-hemorrhage-after-pulmonary-endarterectomy
#19
Stefan Guth, Christoph B Wiedenroth, Marc Wollenschläger, Manuel Jonas Richter, Hossein A Ghofrani, Matthias Arlt, Eckhard Mayer
OBJECTIVES: Pulmonary endarterectomy (PEA) is the only curative treatment option for patients with chronic thromboembolic pulmonary hypertension. Massive endobronchial bleeding that precludes weaning from cardiopulmonary bypass is an often-fatal complication of PEA. The aim of this study was to determine whether short-term extracorporeal membrane oxygenation (ECMO) is a safe and feasible procedure in patients with severe endobronchial bleeding. METHODS: From January 2014 to December 2016, 396 patients (mean age 60 ± 18 years, 54...
February 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29021437/a-systematic-review-of-the-effectiveness-of-antianxiety-and-antidepressive-agents-for-functional-dyspepsia
#20
Mariko Hojo, Akihito Nagahara, Daisuke Asaoka, Yuji Shimada, Hitoshi Sasaki, Kohei Matsumoto, Tsutomu Takeda, Hiroya Ueyama, Kenshi Matsumoto, Sumio Watanabe
Objective Functional dyspepsia (FD) is defined as persistent or recurrent pain or discomfort centered in the upper abdomen without organic disease. Psychosocial factors have been proposed as an important element in the pathophysiology of FD. Therefore, psychotropic agents having antianxiety or antidepressive action are expected to alleviate FD. We previously reported on the treatment of FD using such agents in a systematic review, wherein the effectiveness of the agents on FD was suggested, although there were several limitations...
December 1, 2017: Internal Medicine
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