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Sanjay Sagar, Seid M Adem, Benjamin Struchen, Sarah P Loughran, Michael E Brunjes, Lisa Arangua, Mohamed Aqiel Dalvie, Rodney J Croft, Michael Jerrett, Joel M Moskowitz, Tony Kuo, Martin Röösli
BACKGROUND: The aim of this study was to quantify RF-EMF exposure applying a tested protocol of RF-EMF exposure measurements using portable devices with a high sampling rate in different microenvironments of Switzerland, Ethiopia, Nepal, South Africa, Australia and the United States of America. METHOD: We used portable measurement devices for assessing RF-EMF exposure in 94 outdoor microenvironments and 18 public transport vehicles. The measurements were taken either by walking with a backpack with the devices at the height of the head and a distance of 20-30 cm from the body, or driving a car with the devices mounted on its roof, which was 170-180 cm above the ground...
March 9, 2018: Environment International
Mun Peak Nyon, Lanying Du, Chien-Te Kent Tseng, Christopher A Seid, Jeroen Pollet, Kevin S Naceanceno, Anurodh Agrawal, Abdullah Algaissi, Bi-Hung Peng, Wanbo Tai, Shibo Jiang, Maria Elena Bottazzi, Ulrich Strych, Peter J Hotez
Middle East respiratory syndrome coronavirus (MERS-CoV) has infected at least 2040 patients and caused 712 deaths since its first appearance in 2012, yet neither pathogen-specific therapeutics nor approved vaccines are available. To address this need, we are developing a subunit recombinant protein vaccine comprising residues 377-588 of the MERS-CoV spike protein receptor-binding domain (RBD), which, when formulated with the AddaVax adjuvant, it induces a significant neutralizing antibody response and protection against MERS-CoV challenge in vaccinated animals...
February 26, 2018: Vaccine
Jose Mario Paiva, German Fox-Rabinovich, Edinei Locks Junior, Pietro Stolf, Yassmin Seid Ahmed, Marcelo Matos Martins, Carlos Bork, Stephen Veldhuis
In the aluminum die casting process, erosion, corrosion, soldering, and die sticking have a significant influence on tool life and product quality. A number of coatings such as TiN, CrN, and (Cr,Al)N deposited by physical vapor deposition (PVD) have been employed to act as protective coatings due to their high hardness and chemical stability. In this study, the wear performance of two nanocomposite AlTiN and AlCrN coatings with different structures were evaluated. These coatings were deposited on aluminum die casting mold tool substrates (AISI H13 hot work steel) by PVD using pulsed cathodic arc evaporation, equipped with three lateral arc-rotating cathodes (LARC) and one central rotating cathode (CERC)...
February 28, 2018: Materials
Jianguo Feng, Guantian Yang, Shengwei Zhang, Qi Liu, Seid Mahdi Jafari, David Julian McClements
Microcapsulses can be designed to effectively encapsulate, protect, and control the release of pesticides. In this study, emulsion-solvent evaporation method was used to fabricate microcapsules using dichloromethane as the solvent, polylactic acid (PLA) as the carrier materials, poly(vinyl alcohol) as the emulsifier, and β-cypermethrin as the entrapped pesticide. The effects of process parameters on the microcapsules characteristics (size, loading content, and encapsulation efficiency) were investigated. Also, the release behavior of the β-cypermethrin was measured experimentally and modeled mathematically...
March 1, 2018: Environmental Science and Pollution Research International
Rozina Ambachew Geremew, Beyene Moges Agizie, Abate Assefa Bashaw, Mengistu Endris Seid, Addisu Gize Yeshanew
Background: Sexually transmitted infection (STI) is a major global cause of acute illness, infertility, long-term disability and death, with serious medical and psychological consequences to millions of men, women and infants. Moreover, in Ethiopia, epidemiological studies on STI among STI clinic clients are limited. Therefore, the aim of this study was to determine the prevalence and associated risk factors of sexually transmitted infection (STI). Methods: A cross sectional study was conducted between April and August 2014 among STI clinic clients in Gondar Town hospitals and health centers...
November 2017: Ethiopian Journal of Health Sciences
Michael Seid, George Dellal, Laura E Peterson, Lloyd Provost, Peter A Gloor, David Livingstone Fore, Peter A Margolis
BACKGROUND: Our health care system fails to deliver necessary results, and incremental system improvements will not deliver needed change. Learning health systems (LHSs) are seen as a means to accelerate outcomes, improve care delivery, and further clinical research; yet, few such systems exist. We describe the process of codesigning, with all relevant stakeholders, an approach for creating a collaborative chronic care network (C3N), a peer-produced networked LHS. OBJECTIVE: The objective of this study was to report the methods used, with a diverse group of stakeholders, to translate the idea of a C3N to a set of actionable next steps...
February 22, 2018: JMIR Human Factors
Bizuneh Woldeab, Abebe Beyene, Argaw Ambelu, Ishi Buffam, Seid Tiku Mereta
This research investigated the spatiotemporal variation of water quality in the Gilgel Gibe reservoir, Ethiopia, using physicochemical water quality parameters. Nonparametric tests and multivariate statistical techniques were used to evaluate data sets measured during dry and rainy seasons. Electrical conductivity (EC), pH, biochemical oxygen demand (BOD5 ), total phosphorus (TP), total nitrogen (TN), nitrate (NO3 - ), total dissolved solids (TDSs), and total suspended solids (TSSs) were all significantly different among seasons (Mann-Whitney U test, p < 0...
February 22, 2018: Environmental Monitoring and Assessment
Abdurahaman Seid, Zemenu Tamir, Brhanu Kasanew, Moges Senbetay
OBJECTIVE: Intestinal parasites and H. pylori are well-known for their high prevalence worldwide. Thus, the objective of this study waste assess risk factors and co-infection of intestinal parasites and H. pylori among adult patients with upper gastrointestinal complaints. A hospital-based cross sectional study was conducted among 363 consecutive adult patients from December 10, 2015 to February 30,2016. Stool and venous blood were collected for analysis of Intestinal parasites and H...
February 20, 2018: BMC Research Notes
Sheka Shemsi Seid, Endalew Gemechu Sendo
Background: In Ethiopia, one in 17 children dies before 1 year of age and one in 11 children dies before 5 years. Research that examines the factors influencing the implementation of the Integrated Management of Neonatal and Childhood Illnesses (IMNCI) strategy in Ethiopia is limited. This study aimed to identify the factors compelling the execution of IMNCI by nurses in four districts of West Arsi zone of Ethiopia. Methods: A mixed-method cross-sectional study was conducted from February to March 2016 in West Arsi zone of Oromia regional state, Ethiopia...
2018: Pediatric Health, Medicine and Therapeutics
Maria T Britto, Sandra C Fuller, Heather C Kaplan, Uma Kotagal, Carole Lannon, Peter A Margolis, Stephen E Muething, Pamela J Schoettker, Michael Seid
The US National Academy of Sciences has called for the development of a Learning Healthcare System in which patients and clinicians work together to choose care, based on best evidence, and to drive discovery as a natural outgrowth of every clinical encounter to ensure innovation, quality and value at the point of care. However, the vision of a Learning Healthcare System has remained largely aspirational. Over the last 13 years, researchers, clinicians and families, with support from our paediatric medical centre, have designed, developed and implemented a network organisational model to achieve the Learning Healthcare System vision...
February 5, 2018: BMJ Quality & Safety
Jean A Monro, Basant K Puri
Currently, a psychologically based model is widely held to be the basis for the aetiology and treatment of chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME)/systemic exertion intolerance disease (SEID). However, an alternative, molecular neurobiological approach is possible and in this paper evidence demonstrating a biological aetiology for CFS/ME/SEID is adduced from a study of the history of the disease and a consideration of the role of the following in this disease: nitric oxide and peroxynitrite, oxidative and nitrosative stress, the blood-brain barrier and intestinal permeability, cytokines and infections, metabolism, structural and chemical brain changes, neurophysiological changes and calcium ion mobilisation...
February 6, 2018: Molecular Neurobiology
Hamid Bakhshabadi, HabibOllah Mirzaei, Alireza Ghodsvali, Seid Mahdi Jafari, Aman Mohammad Ziaiifar
Application of novel technologies such as microwave and pulsed electric fields (PEF) might increase the speed and efficiency of oil extraction. In the present research, PEF (3.25 kV/cm electric field intensity and 30 pulse number) and microwave (540 W for 180 s) pretreatments were used to study the process of oil extraction from black cumin (Nigella sativa) seeds. After applying the selected pretreatments, the oil of seeds was extracted with the use of a screw press and the extraction efficiency, refractive index, oil density, color index, oxidative stability, and chemical components of oil and protein of meal were evaluated...
January 2018: Food Science & Nutrition
Ramin Hashemi Tabatabaei, Seid Mahdi Jafari, Habibollah Mirzaei, Abdorreza Mohammadi Nafchi, Danial Dehnad
The main goal of this study was to prepare bionanocomposites by combination of gelatin (10% w/v), k-carrageenan (0.5%) and nano-SiO2 (1, 3 or 5%). Then, mechanical properties (tensile strength, elongation at break, Young's modulus), gas permeability (water vapor, oxygen), water solubility, color, UV-vis transmission/absorbance, water vapor adsorption isotherms and Fourier transform infrared (FTIR) analysis of nanocomposites were evaluated. As the results indicated, inclusion of nano-SiO2 (at each level) could increase tensile strength and Young's modulus significantly, with the latter becoming nearly 110% higher at 5% nanoparticle level compared with gelatin-carrageenan biocompostes...
January 20, 2018: International Journal of Biological Macromolecules
Abdurahaman Seid, Zemenu Tamir, Wondmagegn Demsiss
BACKGROUND: Dyspepsia is a common problem in the community and clinical practice with symptom(s) considered arising from the gastroduodenal region. Dyspepsia burden and associated factors vary from country to country. The aim of this study was to determine the prevalence of uninvestigated dyspepsia (UD) using Rome III criteria, associated risk factors and self-reported dyspepsia symptoms' correlation with H. pylori infection. METHODS: A cross-sectional study was conducted among randomly selected 318 out patients with gastrointestinal complaints during the period from September 1 to December 30, 2015...
January 18, 2018: BMC Gastroenterology
Sérgio Eduardo Alonso Araújo, Marcelli Tainah Marcante, Carlos Ramon Siveira Mendes, Alexandre Bruno Bertoncini, Victor Edmond Seid, Lucas Araujo Horcel, Rodrigo Oliva Perez, Sidney Klajner
BACKGROUND: The best treatment for anal fistula should extirpate infection and promote healing of the tract, whilst preserving the anal sphincter complex and full continence. AIM: To analyze the success rate after a modified technique for ligation of the intersphincteric fistula tract (LIFT) for patients with anal fistulas. METHODS: A prospective (observational cohort study) Brazilian bi-institutional experience with a modified (ligation of the intersphincteric fistula tract without excision) LIFT technique was undertaken...
October 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
Christiane A Müller, Nina Fleischmann, Christoph Cavazzini, Susanne Heim, Svenja Seide, Christina Geister, Britta Tetzlaff, Andreas Hoell, Jochen Werle, Siegfried Weyerer, Martin Scherer, Eva Hummers
BACKGROUND: Given both the increase of nursing home residents forecast and challenges of current interprofessional interactions, we developed and tested measures to improve collaboration and communication between nurses and general practitioners (GPs) in this setting. Our multicentre study has been funded by the German Federal Ministry of Education and Research (FK 01GY1124). METHODS: The measures were developed iteratively in a continuous process, which is the focus of this article...
January 11, 2018: BMC Family Practice
Reza Nafisi Moghadam, Amir Pasha Amlelshahbaz, Nasim Namiranian, Mohammad Sobhan-Ardekani, Mahmood Emami-Meybodi, Ali Dehghan, Masoud Rahmanian, Seid Kazem Razavi-Ratki
Objective: Ultrasonography (US) and parathyroid scintigraphy (PS) with 99mTc-MIBI are common methods for preoperative localization of parathyroid adenomas but there discrepancies exist with regard to diagnostic accuracy. The aim of the study was to compare PS and US for localization of parathyroid adenoma with a systematic review and meta-analysis of the literature. Methods: Pub Med, Scopus (EMbase), Web of Science and the reference lists of all included studies were searched up to 1st January 2016. The search strategy was according PICO characteristics...
December 28, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
Jessica C Kichler, Michael Seid, Jamie Crandell, David M Maahs, Franziska K Bishop, Kimberly A Driscoll, Debra Standiford, Christine M Hunter, Elizabeth Mayer-Davis
The Flexible Lifestyle Empowering Change (FLEX) Intervention Study is a multi-site randomized controlled trial to test the efficacy of an adaptive behavioral intervention to promote self-management for youth with type 1 diabetes mellitus (T1D). This paper details FLEX design, demographic characteristics of the sample, and outcome variables at baseline. Participants were randomized to either an intervention or control arm after their baseline standardized measurement visit. Baseline data for the primary (glycemic levels) and secondary outcome variables (e...
December 22, 2017: Contemporary Clinical Trials
Amadeo B Biter, Sarah Weltje, Elissa M Hudspeth, Christopher A Seid, C Patrick McAtee, Wen-Hsiang Chen, Jeroen B Pollet, Ulrich Strych, Peter J Hotez, Maria Elena Bottazzi
Chagas disease due to chronic infection with Trypanosoma cruzi is a neglected cause of heart disease, affecting approximately 6-10 million individuals in Latin America and elsewhere. T. cruzi Tc24, a calcium-binding protein in the flagellar pocket of the parasite, is a candidate antigen for an injectable therapeutic vaccine as an alternative or a complement to chemotherapy. Previously, we reported that a genetically engineered construct from which all cysteine residues had been eliminated (Tc24-C4) yields a recombinant protein with reduced aggregation and improved analytical purity in comparison to the wild-type form, without compromising antigenicity and immunogenicity...
December 21, 2017: Journal of Pharmaceutical Sciences
David Julian McClements, Seid Mahdi Jafari
The formation, stability, and performance of oil-in-water emulsions may be improved by using combinations of two or more different emulsifiers, rather than an individual type. This article provides a review of the physicochemical basis for the ability of mixed emulsifiers to enhance emulsion properties. Initially, an overview of the most important physicochemical properties of emulsifiers is given, and then the nature of emulsifier interactions in solution and at interfaces is discussed. The impact of using mixed emulsifiers on the formation and stability of emulsions is then reviewed...
December 9, 2017: Advances in Colloid and Interface Science
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