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https://www.readbyqxmd.com/read/28298205/prevalence-and-determinants-of-erectile-dysfunction-among-diabetic-patients-attending-in-hospitals-of-central-and-northwestern-zone-of-tigray-northern-ethiopia-a-cross-sectional-study
#1
Awole Seid, Hadgu Gerensea, Shambel Tarko, Yosef Zenebe, Rahel Mezemir
BACKGROUND: The prevalence of erectile dysfunction among diabetic men varies between 35-90%. Although erectile dysfunction is widespread among men with diabetes, the condition often remains undiagnosed and demands appropriate assessment and prompt treatment. Erectile dysfunction can affect all aspects of a patient's life including physical, emotional, social, sexual, and relationships. The main aim of this study is to determine the prevalence and determinants of erectile dysfunction among diabetic patients attending hospitals in the Central and Northwest zone of Tigray, Ethiopia...
March 15, 2017: BMC Endocrine Disorders
https://www.readbyqxmd.com/read/28288159/determinants-of-anemia-among-pregnant-mothers-attending-antenatal-care-in-dessie-town-health-facilities-northern-central-ethiopia-unmatched-case-control-study
#2
Sisay Eshete Tadesse, Omer Seid, Yemane G/Mariam, Abel Fekadu, Yitbarek Wasihun, Kedir Endris, Abebayehu Bitew
INTRODUCTION: Anemia affects around 38.2% and 22% of pregnant women at a global and national level respectively. In developing countries, women start pregnancy with already depleted body stores of iron and other vitamins with significant variation of anemia within and between regions. OBJECTIVE: To identify the determinants of anemia among pregnant mothers attending antenatal care in Dessie town health facilities, northern central Ethiopia. METHODS: A health facility based unmatched case control study was conducted among 112 cases and 336 controls from January to March 2016 G...
2017: PloS One
https://www.readbyqxmd.com/read/28278244/structure-of-salo-a-leishmaniasis-vaccine-candidate-from-the-sand-fly-lutzomyia-longipalpis
#3
Oluwatoyin A Asojo, Alan Kelleher, Zhuyun Liu, Jeroen Pollet, Elissa M Hudspeth, Wanderson C Rezende, Mallory Jo Groen, Christopher A Seid, Maha Abdeladhim, Shannon Townsend, Waldione de Castro, Antonio Mendes-Sousa, Daniella Castanheira Bartholomeu, Ricardo Toshio Fujiwara, Maria Elena Bottazzi, Peter J Hotez, Bin Zhan, Fabiano Oliveira, Shaden Kamhawi, Jesus G Valenzuela
BACKGROUND: Immunity to the sand fly salivary protein SALO (Salivary Anticomplement of Lutzomyia longipalpis) protected hamsters against Leishmania infantum and L. braziliensis infection and, more recently, a vaccine combination of a genetically modified Leishmania with SALO conferred strong protection against L. donovani infection. Because of the importance of SALO as a potential component of a leishmaniasis vaccine, a plan to produce this recombinant protein for future scale manufacturing as well as knowledge of its structural characteristics are needed to move SALO forward for the clinical path...
March 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28275984/effects-of-human-induced-environmental-changes-on-benthic-macroinvertebrate-assemblages-of-wetlands-in-lake-tana-watershed-northwest-ethiopia
#4
Ayenew Gezie, Wassie Anteneh, Eshete Dejen, Seid Tiku Mereta
Wetlands of Lake Tana Watershed provide various ecological and socioeconomic functions. However, they are losing their vigor at alarming rate due to unwise management. Hence, there is an urgent need to monitor and assess these resources so as to identify the major drivers of its degradation and to provide information for management decisions. In this context, we aimed to assess the effects of human activities on macroinvertebrate assemblages of wetlands in Lake Tana Watershed. Biotic and abiotic data were collected from 46 sampling sites located in eight wetlands...
April 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28274251/knowledge-and-factors-associated-with-pain-management-for-hospitalized-children-among-nurses-working-in-public-hospitals-in-mekelle-city-north-ethiopia-cross-sectional-study
#5
Remla Miftah, Weyzer Tilahun, Atsde Fantahun, Seid Adulkadir, Kahsu Gebrekirstos
BACKGROUND: American Nurses Association reflects, the role of the nurse in pain management encompasses the entire nursing process, assessment of pain, plans pharmacological and non-pharmacological pain management strategies, implements the plan, and evaluates the response of the patient to the interventions. Pediatric pain management has been left largely unaddressed due to factors like limited resources, inadequate training, as well as cultural diversity and language barriers which made sick and injured children not to receive basic pain care...
March 9, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28267757/cubocube-student-creation-of-a-cancer-genetics-e-textbook-using-open-access-software-for-social-learning
#6
Puya Seid-Karbasi, Xin C Ye, Allen W Zhang, Nicole Gladish, Suzanne Y S Cheng, Katharina Rothe, Jessica A Pilsworth, Min A Kang, Natalie Doolittle, Xiaoyan Jiang, Peter C Stirling, Wyeth W Wasserman
Student creation of educational materials has the capacity both to enhance learning and to decrease costs. Three successive honors-style classes of undergraduate students in a cancer genetics class worked with a new software system, CuboCube, to create an e-textbook. CuboCube is an open-source learning materials creation system designed to facilitate e-textbook development, with an ultimate goal of improving the social learning experience for students. Equipped with crowdsourcing capabilities, CuboCube provides intuitive tools for nontechnical and technical authors alike to create content together in a structured manner...
March 2017: PLoS Biology
https://www.readbyqxmd.com/read/28243110/in-vivo-efficacy-of-artemether-lumefantrine-against-uncomplicated-plasmodium-falciparum-malaria-in-dembia-district-northwest-ethiopia
#7
Tekalign Deressa, Mengistu Endris Seid, Wubet Birhan, Yetemwork Aleka, Biniam Mathewos Tebeje
BACKGROUND: Artemether-lumefantrine (AL) has been used as a first-line treatment for uncomplicated Plasmodium falciparum malaria in Ethiopia since 2004. Antimalarial drug resistance is one of the major obstacles for malaria control and curtails the lifespan of several drugs. Thus, continued monitoring of the efficacy of AL is of great public health importance in malaria endemic areas. OBJECTIVE: This study aimed to investigate the therapeutic efficacy and safety of AL for the treatment of uncomplicated P...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28191326/consanguinity-among-parents-of-iranian-deaf-children
#8
Mohammad Ajallouyan, Shokofeh Radfar, Sima Nouhi, Seid Abbas Tavallaie, Susan Amirsalari, Jaleh Yousefi, Mahdieh Hasanali Fard
BACKGROUND: It seems that there is a relationship between consanguinity and profound hearing loss but there is little data about the association of consanguinity and hearing loss in Iran. OBJECTIVES: The aim of this study is to demonstrate the causes of profound bilateral sensorineural hearing loss among Iranian samples who are candidates for cochlear implantation. METHODS: This study was retrospective, analytical, and designed to collect information about profound hearing impaired cases referred to the Baqiyatallah Cochlear implantation center using enumeration...
November 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28181238/tree-species-diversity-affects-decomposition-through-modified-micro-environmental-conditions-across-european-forests
#9
François-Xavier Joly, Alexandru Milcu, Michael Scherer-Lorenzen, Loreline-Katia Jean, Filippo Bussotti, Seid Muhie Dawud, Sandra Müller, Martina Pollastrini, Karsten Raulund-Rasmussen, Lars Vesterdal, Stephan Hättenschwiler
Different tree species influence litter decomposition directly through species-specific litter traits, and indirectly through distinct modifications of the local decomposition environment. Whether these indirect effects on decomposition are influenced by tree species diversity is presently not clear. We addressed this question by studying the decomposition of two common substrates, cellulose paper and wood sticks, in a total of 209 forest stands of varying tree species diversity across six major forest types at the scale of Europe...
February 9, 2017: New Phytologist
https://www.readbyqxmd.com/read/28165444/correlation-between-cervical-infection-and-preterm-labor
#10
Larisa Mešić Ðogić, Nenad Lučić, Dragana Mićić, Feđa Omeragić, Enes Hodžić, Seid Fazlagić, Refka Kovač, Nevenka Pavlović
Aim To investigate a correlation between cervical canal infection and imminent preterm labor and to identify most frequent pathogens. Methods A prospective study was conducted in obstetrics/gynecology departments of Health Center and the University Clinical Center Tuzla, and General Hospital Tešanj (Bosnia and Herzegovina, B&H) between October 2013 and May 2014. An examined group included 50 healthy pregnant women with singleton pregnancy of the gestation age between the 28th and 37th week, with cervical changes that are related to imminent preterm labor...
February 1, 2017: Medicinski Glasnik
https://www.readbyqxmd.com/read/28152499/contributions-of-polyunsaturated-fatty-acids-pufa-on-cerebral-neurobiology-an-integrated-omics-approach-with-epigenomic-focus
#11
Nabarun Chakraborty, Seid Muhie, Raina Kumar, Aarti Gautam, Seshamalini Srinivasan, Bintu Sowe, George Dimitrov, Stacy-Ann Miller, Marti Jett, Rasha Hammamieh
The epigenetic landscape is vulnerable to diets. Here, we investigated the influence of different polyunsaturated fatty acids (PUFA) dietary supplements on rodents' nervous system development and functions and potential consequences to neurodegenerative disorders. Our previous nutrigenomics study showed significant impact of high n-3 PUFA-enriched diet (ERD) on synaptogenesis and various neuromodulators. The present study introduced a second equicaloric diet with n-6 PUFA balanced by n-3 PUFA (BLD). The typical lab diet with high n-6 PUFA was the baseline...
January 5, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28139840/novel-genetic-variants-in-carboxylesterase-1-predict-severe-early-onset-capecitabine-related-toxicity
#12
Seid Hamzic, Dominic Kummer, Sophie Milesi, David Mueller, Markus Joerger, Stefan Aebi, Ursula Amstutz, Carlo R Largiadèr
An important concern with the anticancer drug capecitabine (Cp), an oral prodrug of 5-fluorouracil, are dose-limiting adverse effects, in particular hand-foot syndrome (HFS) and diarrhea. Here, we evaluated the association of genetic variability in all enzymes of the Cp-activation pathway to 5-fluorouracil with Cp-related early-onset toxicity in 144 patients receiving Cp. We identified a haplotype encompassing five variants in the carboxylesterase 1 (CES1) gene region including an expression quantitative trait locus (Haplotype A3: ORadditive =2...
January 31, 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28138894/every-exercise-bout-matters-linking-systemic-exercise-responses-to-breast-cancer-control
#13
REVIEW
Christine Dethlefsen, Katrine Seide Pedersen, Pernille Hojman
Cumulative epidemiological evidence shows that regular exercise lowers the risk of developing breast cancer and decreases the risk of disease recurrence. The causality underlying this relation has not been fully established, and the exercise recommendations for breast cancer patients follow the general physical activity guidelines, prescribing 150 min of exercise per week. Thus, elucidations of the causal mechanisms are important to prescribe and implement the most optimal training regimen in breast cancer prevention and treatment...
January 30, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28116101/prevalence-of-anemia-in-renal-insufficiency-among-hiv-infected-patients-initiating-art-at-a-hospital-in-northeast-ethiopia
#14
Temesgen Fiseha, Zemenu Tamir, Abdurahaman Seid, Wondmagegn Demsiss
BACKGROUND: Anemia is a strong predictor of mortality and poor quality of life among persons with either renal impairment or HIV infection. In this study, we investigated the prevalence of anemia and its association with renal insufficiency among HIV infected patients initiating ART at a hospital in Northeast Ethiopia. METHODS: In this retrospective cohort study, records of 373 patients on ART were selected in Dessie Referral hospital, South Wollo, Northeast Ethiopia from September 2010 to August 2013...
2017: BMC Hematology
https://www.readbyqxmd.com/read/28108908/diamine-oxidase-from-white-pea-lathyrus-sativus-combined-with-catalase-protects-the-human-intestinal-caco-2-cell-line-from-histamine-damage
#15
Catherine Jumarie, Marilyne Séïde, Lucia Marcocci, Paola Pietrangeli, Mircea Alexandru Mateescu
Diamine oxidase (DAO) administration has been proposed to treat certain gastrointestinal dysfunctions induced by histamine, an immunomodulator, signaling, and pro-inflammatory factor. However, H2O2 resulting from the oxidative deamination of histamine by DAO may be toxic. The purpose of this study was to investigate to which extent DAO from white pea (Lathyrus sativus), alone or in combination with catalase, may modulate histamine toxicity in the human intestinal Caco-2 cell line. The results show that histamine at concentrations higher than 1 mM is toxic to the Caco-2 cells, independently of the cell differentiation status, with a LC50 of ≅ 10 mM following a 24-h exposure...
January 20, 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/28068181/ajmq-newsletter
#16
Donald E Casey, Beverly Collins, Arlene Seid, Jerry Abraham, Jason D Hall, Diana Huang
No abstract text is available yet for this article.
January 2017: American Journal of Medical Quality: the Official Journal of the American College of Medical Quality
https://www.readbyqxmd.com/read/27979187/preparation-of-a-multiple-emulsion-based-on-pectin-whey-protein-complex-for-encapsulation-of-saffron-extract-nanodroplets
#17
Afshin Faridi Esfanjani, Seid Mahdi Jafari, Elham Assadpour
The present study illustrates a simple and practical way to produce an adequate delivery system of bioactive compounds of saffron by protein-polysaccharide complex. Frist, crocin, safranal, and picrocrocin were loaded in nanodroplets (<100nm) by using water in oil (W/O) microemulsions contain 5, and 10% aqueous saffron extract as a dispersed phase. These microemulsions were then covered with whey protein concentrate (WPC)-maltodextrin or WPC-pectin-maltodextrin through water in oil in water (W/O/W) multiple emulsions...
April 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27978839/the-impact-of-dietary-risk-factors-on-the-burden-of-non-communicable-diseases-in-ethiopia-findings-from-the-global-burden-of-disease-study-2013
#18
Yohannes Adama Melaku, Awoke Misganaw Temesgen, Amare Deribew, Gizachew Assefa Tessema, Kebede Deribe, Berhe W Sahle, Semaw Ferede Abera, Tolesa Bekele, Ferew Lemma, Azmeraw T Amare, Oumer Seid, Kedir Endris, Abiy Hiruye, Amare Worku, Robert Adams, Anne W Taylor, Tiffany K Gill, Zumin Shi, Ashkan Afshin, Mohammad H Forouzanfar
BACKGROUND: The burden of non-communicable diseases (NCDs) has increased in sub-Saharan countries, including Ethiopia. The contribution of dietary behaviours to the NCD burden in Ethiopia has not been evaluated. This study, therefore, aimed to assess diet-related burden of disease in Ethiopia between 1990 and 2013. METHOD: We used the 2013 Global Burden of Disease (GBD) data to estimate deaths, years of life lost (YLLs) and disability-adjusted life years (DALYs) related to eight food types, five nutrients and fibre intake...
December 16, 2016: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/27970673/is-early-initiation-of-biologic-treatment-more-effective-than-a-step-up-treatment-approach-for-new-onset-juvenile-idiopathic-arthritis-using-a-causal-inference-approach-to-achieve-a-double-robust-estimate
#19
B Huang, E Morgan, C Chen, M Adams, S Sivaganisan, H Brunner, J Guo, M Seid
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27919243/tumour-stage-distribution-and-survival-of-malignant-melanoma-in-germany-2002-2011
#20
Olaf Schoffer, Stefanie Schülein, Gerlinde Arand, Hans Arnholdt, Dieter Baaske, Ralf C Bargou, Nikolaus Becker, Matthias W Beckmann, Yves Bodack, Beatrix Böhme, Tayfun Bozkurt, Regine Breitsprecher, Andre Buchali, Elke Burger, Ulrike Burger, Klaus Dommisch, Gudrun Elsner, Karin Fernschild, Ulrike Flintzer, Uwe Funke, Michael Gerken, Hubert Göbel, Norbert Grobe, Vera Gumpp, Lucie Heinzerling, Lana Raffaela Kempfer, Alexander Kiani, Monika Klinkhammer-Schalke, Sabine Klöcking, Ute Kreibich, Katrin Knabner, Peter Kuhn, Stine Lutze, Uwe Mäder, Tanja Maisel, Jan Maschke, Martin Middeke, Andreas Neubauer, Antje Niedostatek, Anabelle Opazo-Saez, Christoph Peters, Beatrice Schell, Gerhard Schenkirsch, Harald Schmalenberg, Peter Schmidt, Constanze Schneider, Birgit Schubotz, Anika Seide, Paul Strecker, Sabine Taubenheim, Matthias Wackes, Steffen Weiß, Claudia Welke, Carmen Werner, Christian Wittekind, Jörg Wulff, Heike Zettl, Stefanie J Klug
BACKGROUND: Over the past two decades, there has been a rising trend in malignant melanoma incidence worldwide. In 2008, Germany introduced a nationwide skin cancer screening program starting at age 35. The aims of this study were to analyse the distribution of malignant melanoma tumour stages over time, as well as demographic and regional differences in stage distribution and survival of melanoma patients. METHODS: Pooled data from 61 895 malignant melanoma patients diagnosed between 2002 and 2011 and documented in 28 German population-based and hospital-based clinical cancer registries were analysed using descriptive methods, joinpoint regression, logistic regression and relative survival...
December 5, 2016: BMC Cancer
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