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https://www.readbyqxmd.com/read/29330656/3d-imaging-3d-printing-and-3d-virtual-planning-in-endodontics
#1
REVIEW
Pratik Shah, B S Chong
The adoption and adaptation of recent advances in digital technology, such as three-dimensional (3D) printed objects and haptic simulators, in dentistry have influenced teaching and/or management of cases involving implant, craniofacial, maxillofacial, orthognathic and periodontal treatments. 3D printed models and guides may help operators plan and tackle complicated non-surgical and surgical endodontic treatment and may aid skill acquisition. Haptic simulators may assist in the development of competency in endodontic procedures through the acquisition of psycho-motor skills...
January 12, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29330634/corrective-osteotomies-using-patient-specific-3d-printed-guides-a-critical-appraisal
#2
Wouter Rosseels, Michiel Herteleer, An Sermon, Stefaan Nijs, Harm Hoekstra
INTRODUCTION: Over the last decade, the technique of 3D planning has found its way into trauma surgery. The use of this technique in corrective osteotomies for treatment of malunions provides the trauma surgeon with a powerful tool. However, this technique is not entirely straightforward. We aimed to define potential pitfalls of this technique and possible solutions to overcome these shortcomings. MATERIALS AND METHODS: Ten patients with either a uni-, bi- or triplanar malunion of the long bones were included in this study...
January 12, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29330523/closed-loop-control-of-zebrafish-behaviour-in-three-dimensions-using-a-robotic-stimulus
#3
Changsu Kim, Tommaso Ruberto, Paul Phamduy, Maurizio Porfiri
Robotics is continuously being integrated in animal behaviour studies to create customizable, controllable, and repeatable stimuli. However, few systems have capitalized on recent breakthroughs in computer vision and real-time control to enable a two-way interaction between the animal and the robot. Here, we present a "closed-loop control" system to investigate the behaviour of zebrafish, a popular animal model in preclinical studies. The system allows for actuating a biologically-inspired 3D-printed replica in a 3D workspace, in response to the behaviour of a zebrafish...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29327779/locally-delivered-ethyl-2-5-dihydroxybenzoate-using-3d-printed-bone-implant-for-promotion-of-bone-regeneration-in-a-osteoporotic-animal-model
#4
B-J Kwon, G M Seon, M H Lee, M-A Koo, M S Kim, D Kim, J-J Han, D Kim, J Kim, J-C Park
Osteoporosis is a disease characterized by low bone mass, most commonly caused by an increase in bone resorption that is not matched by sufficient bone formation. The most common complications of postmenopausal osteoporosis are bone-related defects and fractures. Fracture healing is a multifactorial bone regeneration process, influenced by both biological and mechanical factors related to age, osteoporosis and stability of the osteosynthesis. During the treatment of bone defects in osteoporotic conditions, imbalanced bone remodeling is the leading cause for implant failure...
January 12, 2018: European Cells & Materials
https://www.readbyqxmd.com/read/29327553/-preliminary-development-of-drill-template-assisted-placement-of-reverse-intramedullary-lag-screw-for-superior-ramus-of-pubis-using-three-dimentional-print-technique
#5
Yi Zheng, Xin-Hua Yuan, Wei-Bin Wang, Qing-Jiang Pang
OBJECTIVE: To investigate the feasibility of a drill template for the placement of reverse intramedullary lag screws on the outside of the pubis based on digital design and 3D printing technology. METHODS: The preoperative CT images of a 23-year-old male patient with pelvic fracture were collected retrospectively. According to the Young and Burgess classification, the type of pelvic fracture was LC IIwith the 3D printing technology. The data was reconstructed by 3D imaging reconstruction software to produce 1:1 three dimensional model...
January 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29325763/clinical-experience-with-three-dimensional-printing-techniques-in-orthopedic-trauma
#6
Ji Wan Kim, Yongkoo Lee, Joonho Seo, Jai Hyung Park, Yong Min Seo, Sung Soo Kim, Hyun Chul Shon
BACKGROUND: To report our experiences with the use of three-dimensional (3D) printing in the field of orthopedic trauma. METHODS: This retrospective study enrolled 24 patients from three university teaching hospitals in whom 3D printing technique was applied: 14 patients with acetabular fractures and 10 patients with clavicular shaft fractures. We summarized our experiences with 3D printed bone models. RESULTS: Three-dimensional printed acetabular models improved understanding of complex acetabular anatomy and fracture pattern to plan the optimal positioning of a reduction clamp and the trajectory of screws...
January 8, 2018: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29323240/engineered-3d-printed-artificial-axons
#7
Daniela Espinosa-Hoyos, Anna Jagielska, Kimberly A Homan, Huifeng Du, Travis Busbee, Daniel G Anderson, Nicholas X Fang, Jennifer A Lewis, Krystyn J Van Vliet
Myelination is critical for transduction of neuronal signals, neuron survival and normal function of the nervous system. Myelin disorders account for many debilitating neurological diseases such as multiple sclerosis and leukodystrophies. The lack of experimental models and tools to observe and manipulate this process in vitro has constrained progress in understanding and promoting myelination, and ultimately developing effective remyelination therapies. To address this problem, we developed synthetic mimics of neuronal axons, representing key geometric, mechanical, and surface chemistry components of biological axons...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29323129/comparison-of-adaptation-between-the-major-connectors-fabricated-from-intraoral-digital-impressions-and-extraoral-digital-impressions
#8
Ning Gan, Yaye Ruan, Jian Sun, Yaoyang Xiong, Ting Jiao
The objective was to compare the adaptation between the major connectors of removable partial dentures derived from intraoral digital impressions and extraoral digital impressions. Twenty-four volunteers were enrolled. Each volunteer received an intraoral digital impression and one extraoral digital impression digitized from conventional gypsum impression. A software was used to create the major connectors on digital impression datasets. After all the virtual major connectors designed from Group intraoral digital impressions (Group I) and Group extraoral digital impressions (Group E) were directly fabricated by 3D printing technique, the adaptation of the final major connectors in volunteers' mouths were measured...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29322768/identification-of-novel-inks-for-3d-printing-using-high-throughput-screening-bioresorbable-photocurable-polymers-for-controlled-drug-delivery
#9
Iria Louzao, Britta Koch, Vincenzo Taresco, Laura Ruiz Cantu, Derek J Irvine, Clive J Roberts, Christopher J Tuck, Cameron Alexander, Richard J M Hague, Ricky D Wildman, Morgan Russell Alexander
A robust discovery methodology is presented to identify novel biomaterials suitable for 3D printing. Currently the application of Additive Manufacturing is limited by the availability of functional inks, especially in the area of biomaterials-this method tackles this problem for the first time allowing hundreds of formulations to be readily assessed. Several functional properties, including the release of an antidepressive drug (paroxetine), cytotoxicity and printability are screened for 253 new ink formulations in a high-throughput format as well as mechanical properties...
January 11, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29320560/measurements-agreement-between-low-cost-and-high-level-handheld-3d-scanners-to-scan-the-knee-for-designing-a-3d-printed-knee-brace
#10
Yoann Dessery, Jari Pallari
Use of additive manufacturing is growing rapidly in the orthotics field. This technology allows orthotics to be designed directly on digital scans of limbs. However, little information is available about scanners and 3D scans. The aim of this study is to look at the agreement between manual measurements, high-level and low-cost handheld 3D scanners. We took two manual measurements and three 3D scans with each scanner from 14 lower limbs. The lower limbs were divided into 17 sections of 30mm each from 180mm above the mid-patella to 300mm below...
2018: PloS One
https://www.readbyqxmd.com/read/29318224/a-highly-efficient-waterborne-photoinitiator-for-visible-light-induced-three-dimensional-printing-of-hydrogels
#11
Jieping Wang, Sascha Stanic, Altan Alpay Altun, Martin Schwentenwein, Kurt Dietliker, Lu Jin, Jürgen Stampfl, Stefan Baudis, Robert Liska, Hansjörg Grützmacher
A bis(acyl)phosphane oxide (BAPO) photoinitiator was conveniently synthesized in an efficient one-pot process. It shows excellent dispersibility in water, good storage stability, and high photo-reactivity in 3D printing of hydrogels under visible-light irradiation (460 nm).
January 10, 2018: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29317370/3d-printed-gelatin-scaffolds-of-differing-pore-geometry-modulate-hepatocyte-function-and-gene-expression
#12
Phillip L Lewis, Richard M Green, Ramille N Shah
Three dimensional (3D) printing is highly amenable to the fabrication of tissue-engineered organs of a repetitive microstructure such as the liver. The creation of uniform and geometrically repetitive tissue scaffolds can also allow for the control over cellular aggregation and nutrient diffusion. However, the effect of differing geometries, while controlling for pore size, has yet to be investigated in the context of hepatocyte function. In this study, we show the ability to precisely control pore geometry of 3D-printed gelatin scaffolds...
January 6, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29316290/a-3d-bioprinted-in-situ-conjugated-co-fabricated-scaffold-for-potential-bone-tissue-engineering-applications
#13
Mduduzi N Sithole, Pradeep Kumar, Lisa C du Toit, Thashree Marimuthu, Yahya E Choonara, Viness Pillay
There is a demand for progressive approaches in bone tissue engineering to repair and regenerate bone defects resulting from trauma or disease. This investigation sought to engineer a single-step in situ conjugated polymeric scaffold employing 3D printing technology as an innovative fabricating tool. A polymeric scaffold was engineered in situ employing sodium alginate as a bio-ink which interacted with a poly(ethyleneimine) solution on bioprinting to form a polyelectrolyte complex through ionic bond formation...
January 9, 2018: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29315710/an-improved-design-to-capture-magnetic-microparticles-for-capillary-electrophoresis-based-immobilized-microenzyme-reactors
#14
Pranov Ramana, Jan Schejbal, Kristof Houthoofd, Johan Martens, Erwin Adams, Patrick Augustijns, Zdenĕk Glatz, Ann Van Schepdael
In this paper, we demonstrate the effectiveness of a new 3D printed magnet holder that enables capture of magnetic microparticles in commercially available capillary electrophoresis equipment with a liquid or air based coolant system. The design as well as the method to capture magnetic microparticles inside the capillary are discussed. This setup was tested at temperature and pH values suitable for performing enzymatic reactions. To demonstrate its applicability in CE- immobilized microenzyme reactors (IMER) development, human flavin-containing monooxygenase 3 and bovine serum albumin were immobilized on amino functionalized magnetic microparticles using glutaraldehyde...
January 5, 2018: Electrophoresis
https://www.readbyqxmd.com/read/29314616/3d-extrusion-bioprinting-of-single-and-double-network-hydrogels-containing-dynamic-covalent-crosslinks
#15
Leo L Wang, Christopher B Highley, Yi-Cheun Yeh, Jonathan H Galarraga, Selen Uman, Jason A Burdick
The fabrication of three-dimensional (3D) scaffolds is indispensable to tissue engineering and 3D printing is emerging as an important approach towards this. Hydrogels are often used as inks in extrusion-based 3D printing, including with encapsulated cells; however, numerous challenging requirements exist, including appropriate viscosity, the ability to stabilize after extrusion, and cytocompatibility. Here, we present a shear-thinning and self-healing hydrogel crosslinked through dynamic covalent chemistry for 3D bioprinting...
January 3, 2018: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29313536/the-effect-of-ordered-and-partially-ordered-surface-topography-on-bone-cell-responses-a-review
#16
REVIEW
N Gui, W Xu, D E Myers, R Shukla, H P Tang, M Qian
Implant surfaces play important roles in regulating protein adsorption and determining subsequent cell responses, including cell attachment, proliferation, migration and differentiation. With rapid developments in micro- and nano-fabrication methods and additive manufacturing (3D printing) technologies, precisely controlled patterns such as partially ordered or ordered patterns can now be generated on bone implant surfaces, rather than restricted to randomly roughened surfaces. Over the last two decades, much effort has been dedicated to manipulating cell responses through surface topographical modifications...
January 9, 2018: Biomaterials Science
https://www.readbyqxmd.com/read/29312871/patient-specific-three-dimensional-printing-for-pre-surgical-planning-in-hepatocellular-carcinoma-treatment
#17
Elizabeth Perica, Zhonghua Sun
Background: Recently, three-dimensional (3D) printing has shown great interest in medicine, and 3D printed models may be rendered as part of the pre-surgical planning process in order to better understand the complexities of an individual's anatomy. The aim of this study is to investigate the feasibility of utilising 3D printed liver models as clinical tools in pre-operative planning for resectable hepatocellular carcinoma (HCC) lesions. Methods: High-resolution contrast-enhanced computed tomography (CT) images were acquired and utilized to generate a patient-specific 3D printed liver model...
December 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29311547/a-non-dispersion-strategy-for-large-scale-production-of-ultra-high-concentration-graphene-slurries-in-water
#18
Lei Dong, Zhongxin Chen, Xiaoxu Zhao, Jianhua Ma, Shan Lin, Mengxiong Li, Yang Bao, Leiqiang Chu, Kai Leng, Hongbin Lu, Kian Ping Loh
It is difficult to achieve high efficiency production of hydrophobic graphene by liquid phase exfoliation due to its poor dispersibility and the tendency of graphene sheets to undergo π-π stacking. Here, we report a water-phase, non-dispersion exfoliation method to produce highly crystalline graphene flakes, which can be stored in the form of a concentrated slurry (50 mg mL-1) or filter cake for months without the risk of re-stacking. The as-exfoliated graphene slurry can be directly used for 3D printing, as well as fabricating conductive graphene aerogels and graphene-polymer composites, thus avoiding the use of copious quantities of organic solvents and lowering the manufacturing cost...
January 8, 2018: Nature Communications
https://www.readbyqxmd.com/read/29310677/chest-wall-reconstruction-with-a-customized-titanium-alloy-prosthesis-fabricated-by-3d-printing-and-rapid-prototyping
#19
Xiaopeng Wen, Shan Gao, Jinteng Feng, Shuo Li, Rui Gao, Guangjian Zhang
BACKGROUND: As 3D printing technology emerge, there is increasing demand for a more customizable implant in the repair of chest-wall bony defects. This article aims to present a custom design and fabrication method for repairing bony defects of the chest wall following tumour resection, which utilizes three-dimensional (3D) printing and rapid-prototyping technology. METHODS: A 3D model of the bony defect was generated after acquiring helical CT data. A customized prosthesis was then designed using computer-aided design (CAD) and mirroring technology, and fabricated using titanium-alloy powder...
January 8, 2018: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29310359/natural-teeth-retained-splint-based-on-a-patient-specific-3d-printed-mandible-used-for-implant-surgery-and-vestibuloplasty-a-case-report
#20
Helin Xing, Jinshuang Wu, Lei Zhou, Sefei Yang
RATIONALE: With respect to improving the quality of oral rehabilitation, the management of keratinized mucosa is as important as bone condition for implant success. To enhance this management, a natural teeth-retained splint based on a patient-specific 3-dimensional (3D) printed mandible was used in vestibuloplasty to provide sufficient keratinized mucosa around dental implants to support long-term implant maintenance. PATIENT CONCERNS: A 28-year-old male patient had a fracture of the anterior andible 1 year ago, and the fracture was treated with titanium...
December 2017: Medicine (Baltimore)
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