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https://www.readbyqxmd.com/read/28211039/cutaneous-squamous-cell-carcinoma-an-epidemiological-review
#1
REVIEW
A C Green, C M Olsen
Cutaneous squamous cell carcinoma (SCC) is a common cancer in white populations and its disease burden is often substantially underestimated. SCC occurs more often in men than women and increases dramatically with age; those affected often develop multiple primaries over time, which increases the burden. The main external cause is solar ultraviolet radiation (UVR), with immunosuppression being the other established risk factor, shown by the high SCC rates in organ transplant recipients. Sunbed use and certain genetic disorders and medical conditions are also associated with SCC, while associations with human papillomavirus infection and high bodyweight are not established...
February 16, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28208977/comparison-of-levosimendan-milrinone-and-dobutamine-in-treating-low-cardiac-output-syndrome-following-valve-replacement-surgeries-with-cardiopulmonary-bypass
#2
Sunny, Mohd Yunus, Habib Md Reazaul Karim, Manuj Kumar Saikia, Prithwis Bhattacharyya, Samarjit Dey
INTRODUCTION: Low Cardiac Output Syndrome (LCOS) following Cardiopulmonary Bypass (CPB) is common and associated with increased mortality. Maintenance of adequate cardiac output is one of the primary objectives in management of such patients. AIM: To compare Levosimendan, Milrinone and Dobutamine for the treatment of LCOS after CPB in patients who underwent valve replacement surgeries. MATERIALS AND METHODS: Sixty eligible patients meeting LCOS were allocated into three treatment groups: Group A-Levosimendan (loading dose 10μg/kg over 10 minutes, followed by 0...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28207400/a-low-cost-adaptive-balance-training-platform-for-stroke-patients-a-usability-study
#3
Sunny Verma, Deepesh Kumar, Animesh Kumawat, Anirban Dutta, Uttama Lahiri
Stroke patients usually suffer from asymmetric posture due to hemi-paresis that can result in reduced postural controllability leading to a balance deficit. This deficit increases the risk of falls, which often makes them dependent on caregivers for community ambulation, thus deteriorating their quality of life. Conventional balance training involves rehabilitation exercises performed under physiotherapist's supervision where the scarcity of trained professionals as well as the cost of clinic-based rehabilitation programs can deter stroke survivors from undergoing regular balance training...
February 9, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28207372/methods-employed-to-assess-weight-loss-in-older-adults-by-means-of-electronic-medical-records-a-systematic-review
#4
Sunny Chen, William A Banks, Julie Silverman, Meera Sheffrin, Stephen M Thielke
Electronic medical records (EMRs) can be used to identify and categorize weight loss in older adults, but research has not scrutinized methods for doing so. Through a modified PRISMA protocol, we systematically reviewed published methods for quantifying weight change from EMRs. Articles (all available through July 2016) were identified through PubMed and SCOPUS searches, screened, and evaluated. We abstracted relevant data and tabulated the methods to assess weight change. The 13 selected articles showed little consistency in the approach to key methodological issues: 1) time ranges assessed; 2) removal of spurious values; 3) metrics to quantify weight change; 4) number of measures needed to estimate change; 5) threshold for significant weight change; and 6) relation to ideal weight...
January 2017: Journal of Nutrition in Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28205519/mitochondrial-atp-transporter-depletion-protects-mice-against-liver-steatosis-and-insulin-resistance
#5
Joonseok Cho, Yujian Zhang, Shi-Young Park, Anna-Maria Joseph, Chul Han, Hyo-Jin Park, Srilaxmi Kalavalapalli, Sung-Kook Chun, Drake Morgan, Jae-Sung Kim, Shinichi Someya, Clayton E Mathews, Young Jae Lee, Stephanie E Wohlgemuth, Nishanth E Sunny, Hui-Young Lee, Cheol Soo Choi, Takayuki Shiratsuchi, S Paul Oh, Naohiro Terada
Non-alcoholic fatty liver disease (NAFLD) is a common metabolic disorder in obese individuals. Adenine nucleotide translocase (ANT) exchanges ADP/ATP through the mitochondrial inner membrane, and Ant2 is the predominant isoform expressed in the liver. Here we demonstrate that targeted disruption of Ant2 in mouse liver enhances uncoupled respiration without damaging mitochondrial integrity and liver functions. Interestingly, liver specific Ant2 knockout mice are leaner and resistant to hepatic steatosis, obesity and insulin resistance under a lipogenic diet...
February 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/28204757/subthreshold-psychosis-in-22q11-2-deletion-syndrome-multisite-naturalistic-study
#6
Omri Weisman, Yael Guri, Raquel E Gur, Donna M McDonald-McGinn, Monica E Calkins, Sunny X Tang, Beverly Emanuel, Elaine H Zackai, Stephan Eliez, Maude Schneider, Marie Schaer, Wendy R Kates, Kevin M Antshel, Wanda Fremont, Vandana Shashi, Stephen R Hooper, Marco Armando, Stefano Vicari, Maria Pontillo, Leila Kushan, Maria Jalbrzikowski, Carrie E Bearden, Joseph F Cubells, Opal Y Ousley, Elaine F Walker, Tony J Simon, Joel Stoddard, Tara A Niendam, Marianne B M van den Bree, Doron Gothelf
No abstract text is available yet for this article.
February 13, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28195811/determinants-of-patient-centered-financial-stress-in-patients-with-locally-advanced-head-and-neck-cancer
#7
Jonas A de Souza, Sunny Kung, Jeremy O'Connor, Bonnie J Yap
PURPOSE: To prospectively estimate patient-centered financial stress and its relationship with health care utilization in patients with head and neck cancer. This was a survey-based, longitudinal, prospective study of treatment-naïve patients with stage III, IVa, or IVb locally advanced head and neck cancer at a single-institution tertiary care hospital from May 2013 to November 2014. With 121 patients approached, 73 (60%) agreed to participate. METHODS: Self-reported data were collected on demographics, income, wealth, cost-coping strategies, out-of-pocket costs, supportive medication compliance, and perceived social isolation...
February 14, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28188568/a-comprehensive-electronic-health-record-based-patient-navigation-module-including-technology-driven-colorectal-cancer-outreach-and-education
#8
Sunny Ajeesh, Rustveld Luis
The purpose of this concept paper is to propose an innovative multifaceted patient navigation module embedded in the Electronic Health Record (EHR) to address barriers to efficient and effective colorectal cancer (CRC) care. The EHR-based CRC patient navigation module will include several patient navigation features: (1) CRC screening registry; (2) patient navigation data, including CRC screening data, outcomes of patient navigation including navigation status (CRC screening referrals, fecal occult blood test (FOBT) completed, colonoscopy scheduled and completed, cancelations, reschedules, and no-shows); (3) CRC counseling aid; and 4) Web-based CRC education application including interactive features such as a standardized colonoscopy preparation guide, modifiable CRC risk factors, and links to existing resources...
February 10, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28188354/simultaneous-extraction-and-determination-of-monoamine-neurotransmitters-in-human-urine-for-clinical-routine-testing-based-on-a-dual-functional-solid-phase-extraction-assisted-by-phenylboronic-acid-coupled-with-liquid-chromatography-tandem-mass-spectrometry
#9
Xiaoguang Sunny Li, Shu Li, Gottfried Kellermann
The major monoamine neurotransmitters, serotonin (5-HT) and catecholamines (i.e., norepinephrine (NE), epinephrine (E), and dopamine (DA)), are critical to the nervous system function, and imbalances of the neurotransmitters have been connected to a variety of diseases, making their measurement useful in a clinical setting. A simple, rapid, robust, sensitive, and specific LC-MS/MS method has been developed and validated for the simultaneous quantitation of urinary serotonin and catecholamines with low cost, which is ideal for routine clinical applications...
February 10, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28182469/health-behavior-models-for-informing-digital-technology-interventions-for-individuals-with-mental-illness
#10
John A Naslund, Kelly A Aschbrenner, Sunny Jung Kim, Gregory J McHugo, Jürgen Unützer, Stephen J Bartels, Lisa A Marsch
OBJECTIVE: Theoretical models offer valuable insights for designing effective and sustainable behavioral health interventions, yet the application of theory for informing digital technology interventions for people with mental illness has received limited attention. We offer a perspective on the importance of applying behavior theories and models to developing digital technology interventions for addressing mental and physical health concerns among people with mental illness. METHOD: In this commentary, we summarize prominent theories of human behavior, highlight key theoretical constructs, and identify opportunities to inform digital health interventions for people with mental illness...
February 9, 2017: Psychiatric Rehabilitation Journal
https://www.readbyqxmd.com/read/28180125/relationship-between-air-pollution-weather-traffic-and-traffic-related-mortality
#11
Maryam Dastoorpoor, Esmaeil Idani, Narges Khanjani, Gholamreza Goudarzi, Abbas Bahrampour
BACKGROUND: Air pollution and weather are just two of many environmental factors contributing to traffic accidents (RTA). OBJECTIVES: This study assessed the effects of these factors on traffic accidents and related mortalities in Ahvaz, Iran. METHODS: In this ecological study, data about RTA, traffic-related mortalities, air pollution (including NO, CO, NO2, NOx PM10, SO2, and O3 rates) and climate data from March 2008 until March 2015 was acquired from the Khuzestan State Police Force, the Environmental Protection Agency and the State Meteorological Department...
September 2016: Trauma Monthly
https://www.readbyqxmd.com/read/28179723/the-impact-of-a-standalone-patient-centered-communication-course-series-on-student-achievement-preparedness-and-attitudes
#12
Jennifer M Trujillo, Chelsea D McNair, Sunny A Linnebur, Connie Valdez, Toby C Trujillo
Objective. To evaluate the impact of a standalone, patient-centered communication (PCC) course series on student achievement of and perceived preparedness for PCC skills and to assess student attitudes regarding learning methods used. Design. During curriculum renewal, a standalone PCC course series that integrated horizontally and vertically within the curriculum was developed. Student achievement of outcomes was evaluated by aggregate performance on simulated evaluations. Students who completed the PCC series were surveyed to assess preparedness and attitudes...
December 25, 2016: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28176531/37th-british-mass-spectrometry-society-annual-meeting
#13
Patricia Wright, Christine Eckers
The 37th British Mass Spectrometry Society (BMSS) annual meeting took place over a brilliantly sunny 3 days by the sea in the historic Eastbourne Winter Gardens on the south coast of England. It was held between 13 and 15 September 2016. Two-hundred attendees enjoyed a conference covering all aspects of MS with speakers drawn from across Europe and North America. The BMSS is particularly proud of the encouragement it offers students and early career scientists, both financially in the form of travel grants and also in terms of opportunities to present at an international level in a supportive atmosphere...
February 8, 2017: Bioanalysis
https://www.readbyqxmd.com/read/28169608/vitamin-d-deficiency-in-pregnant-ukrainian-women-effects-of-alcohol-consumption-on-vitamin-d-status
#14
Charles R Carlson, Janet Y Uriu-Adams, Christina D Chambers, Lyubov Yevtushok, Natalya Zymak-Zakutnya, Priscilla H Chan, Jordan J Schafer, Wladimir Wertelecki, Carl L Keen
OBJECTIVE: Heavy alcohol consumption can alter vitamin D status; however, the relationships between alcohol consumption and vitamin D concentrations in pregnant women have not been well studied. The aim of this study was to investigate the vitamin D status in a population of alcohol-exposed (N = 180) and low/unexposed control (N = 179) Ukrainian pregnant women. METHODS: Women who attended prenatal care facilities in 2 regions of Ukraine (Rivne and Khmelnytsky) for a routine prenatal visit were screened for the study...
January 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28166577/longitudinal-hypertension-outcomes-at-four-student-run-free-clinic-sites
#15
Sunny D Smith, Steven M Rojas, Junwen Huang, Kuangyi Yang, Florin Vaida
BACKGROUND AND OBJECTIVES: Student-Run Free Clinics (SRFCs) play a significant role in medical education yet there is minimal information about patient outcomes over time in this setting. The purpose of this study was to assess longitudinal outcomes of hypertension management during routine care at four SRFC sites, while comparing control rates with national standards, and examining for characteristics independently associated with uncontrolled hypertension. METHODS: The authors conducted a retrospective medical record review of visits from January 2004 through April 2016 with an initial visit for hypertension and a follow-up visit 9 to 15 months later...
January 2017: Family Medicine
https://www.readbyqxmd.com/read/28165705/rapid-conversion-from-carbohydrates-to-large-scale-carbon-quantum-dots-for-all-weather-solar-cells
#16
Qunwei Tang, Wanlu Zhu, Benlin He, Peizhi Yang
A great challenge for state-of-the-art solar cells is to generate electricity in all weather. We present here the rapid conversion of carbon quantum dots (CQDs) from carbohydrates (including glucose, maltol, sucrose) for an all-weather solar cell, which comprises a CQD-sensitized mesoscopic titanium dioxide/long-persistence phosphor (m-TiO2/LPP) photoanode, a I(-)/I3(-) redox electrolyte, and a platinum counter electrode. In virtue of the light storing and luminescent behaviors of LPP phosphors, the generated all-weather solar cells can not only convert sunlight into electricity on sunny days but persistently realize electricity output in all dark-light conditions...
February 8, 2017: ACS Nano
https://www.readbyqxmd.com/read/28161533/prevalence-determinants-and-clinical-correlates-of-vitamin-d-deficiency-in-patients-with-chronic-obstructive-pulmonary-disease-in-london-uk
#17
David A Jolliffe, Wai Yee James, Richard L Hooper, Neil C Barnes, Claire L Greiller, Kamrul Islam, Angshu Bhowmik, Peter M Timms, Raj K Rajakulasingam, Aklak B Choudhury, David E Simcock, Elina Hyppönen, Robert T Walton, Christopher J Corrigan, Christopher J Griffiths, Adrian R Martineau
Vitamin D deficiency is common in patients with chronic obstructive pulmonary disease (COPD), yet a comprehensive analysis of environmental and genetic determinants of serum 25-hydroxyvitamin D (25[OH]D) concentration in patients with this condition is lacking. We conducted a multi-centre cross-sectional study in 278 COPD patients aged 41-92 years in London, UK. Details of potential environmental determinants of vitamin D status and COPD symptom control and severity were collected by questionnaire, and blood samples were taken for analysis of serum 25(OH)D concentration and DNA extraction...
February 1, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28161111/-prevalence-and-risk-factors-of-vitamin-d-deficiency-in-healthy-adults-aged-18-65%C3%A2-years-in-northern-france
#18
X Deplanque, A Wullens, L Norberciak
INTRODUCTION: Screening and treatment of vitamin D deficiency are the subject of several publications. A lot of recognized risk factors have increased steadily, leading to the recognition of populations at risk. Despite their exposure to the same risk factors as other populations, there are no recommendations concerning healthy adults, a population rarely studied. To determine the prevalence of vitamin D deficiency in healthy adults aged 18-65 years residing in northern France and to search for correlated risk factors at 20ng/mL...
February 1, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/28158570/couples-body-composition-and-time-to-pregnancy
#19
Rajeshwari Sundaram, Sunni L Mumford, Germaine M Buck Louis
No abstract text is available yet for this article.
February 3, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28155313/vitamin-d-status-hypertension-and-body-mass-index-in-an-urban-black-community-in-mangaung-south-africa
#20
Ronette Lategan, Violet L Van den Berg, Jasminka Z Ilich, Corinna M Walsh
BACKGROUND: A strong relationship exists between hypertension and body weight. Research has linked both higher blood pressure and body weight with lower vitamin D status. OBJECTIVE: This study assessed the vitamin D status of a low-income, urban, black community in South Africa, to examine whether serum levels of 25-hydroxy vitamin D [25(OH)D] are associated with hypertension and body mass index (BMI). METHODS: Data collected from 339 adults (25-64 years) from the Assuring Health for All in the Free State (AHA-FS) study were analysed...
October 31, 2016: African Journal of Primary Health Care & Family Medicine
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