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https://www.readbyqxmd.com/read/28445799/hysteroscopic-polypectomy-prior-to-infertility-treatment-a-cost-analysis-and-systematic-review
#1
REVIEW
Youssef Mouhayar, Ophelia Yin, Sunni L Mumford, James H Segars
The cost of fertility treatment is expensive and interventions that reduce cost can lead to greater efficiency and fewer embryos transferred. Endometrial polyps contribute to infertility and are frequently removed prior to infertility treatment. It is unclear whether polypectomy reduces fertility treatment cost and if so, the magnitude of cost reduction afforded by the procedure. The aim of this study was to determine whether performing office or operative hysteroscopic polypectomy prior to infertility treatment would be cost-effective...
April 13, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28445731/hair-follicle-terminal-differentiation-is-orchestrated-by-distinct-early-and-late-matrix-progenitors
#2
Arlee L Mesler, Natalia A Veniaminova, Madison V Lull, Sunny Y Wong
During development and regeneration, matrix progenitors undergo terminal differentiation to form the concentric layers of the hair follicle. These differentiation events are thought to require signals from the mesenchymal dermal papilla (DP); however, it remains unclear how DP-progenitor cell interactions govern specific cell fate decisions. Here, we show that the hair follicle differentiated layers are specified asynchronously, with early matrix progenitors initiating differentiation before surrounding the DP...
April 25, 2017: Cell Reports
https://www.readbyqxmd.com/read/28442898/medication-regimen-complexity-in-ambulatory-older-adults-with-heart-failure
#3
Michael R Cobretti, Robert L Page, Sunny A Linnebur, Kimberly M Deininger, Amrut V Ambardekar, JoAnn Lindenfeld, Christina L Aquilante
PURPOSE: Heart failure prevalence is increasing in older adults, and polypharmacy is a major problem in this population. We compared medication regimen complexity using the validated patient-level Medication Regimen Complexity Index (pMRCI) tool in "young-old" (60-74 years) versus "old-old" (75-89 years) patients with heart failure. We also compared pMRCI between patients with ischemic cardiomyopathy (ISCM) versus nonischemic cardiomyopathy (NISCM). PATIENTS AND METHODS: Medication lists were retrospectively abstracted from the electronic medical records of ambulatory patients aged 60-89 years with heart failure...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28440094/small-group-activities-within-academic-communities-improve-the-connectedness-of-students-and-faculty
#4
Katharina Brandl, Stephen D Schneid, Sunny Smith, Babbi Winegarden, Jess Mandel, Carolyn J Kelly
BACKGROUND: The University of California, San Diego, School of Medicine implemented a curriculum change that included reduction of lectures, incorporation of problem-based learning and other small group activities. Six academic communities were introduced for teaching longitudinal curricular content and organizing extracurricular activities. METHODS: Surveys were collected from 904 first- and second-year medical students over 6 years. Student satisfaction data with their sense of connectedness and community support were collected before and after the implementation of the new curriculum...
April 25, 2017: Medical Teacher
https://www.readbyqxmd.com/read/28436867/rscm-region-selection-and-concurrency-model-for-multi-class-weather-classification
#5
Di Lin, Cewu Lu, Hui Huang, Jiaya Jia
Towards weather condition recognition, we emphasize the importance of regional cues in this paper and address a few important problems regarding appropriate representation, its differentiation among regions, and weather-condition feature construction. Our major contribution is, first, to construct a multi-class benchmark dataset containing 65,000 images from 6 common categories for sunny, cloudy, rainy, snowy, haze and thunder weather. This dataset also benefits weather classification and attribute recognition...
April 19, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28433949/the-dimensional-structure-of-psychopathology-in-22q11-2-deletion-syndrome
#6
Maria Niarchou, Tyler M Moore, Sunny X Tang, Monica E Calkins, Donna M McDonald-McGuinn, Elaine H Zackai, Beverly S Emanuel, Ruben C Gur, Raquel E Gur
BACKGROUND: 22q11.2 Deletion Syndrome (22q11.2DS) is one of the strongest known genetic risk factors for developing schizophrenia. Individuals with 22q11.2DS have high rates of neurodevelopmental disorders in childhood, while in adulthood ∼25% develop schizophrenia. Similar to the general population, high rates of comorbidity are common in 22q11.2DS. Employing a dimensional approach where psychopathology is examined at the symptom-level as complementary to diagnostic categories in a population at such high genetic risk for schizophrenia can help gain a better understanding of how psychopathology is structured as well as its genetic underpinnings...
April 15, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28433605/stability-of-patient-specific-features-of-altered-dna-replication-timing-in-xenografts-of-primary-human-acute-lymphoblastic-leukemia
#7
Takayo Sasaki, Juan Carlos Rivera-Mulia, Daniel Vera, Jared Zimmerman, Sunny Das, Michelle Padget, Naoto Nakamichi, Bill H Chang, Jeff Tyner, Brian J Druker, Andrew P Weng, Curt I Civin, Connie J Eaves, David M Gilbert
Genome-wide DNA replication timing (RT) profiles reflect the global 3D chromosome architecture of cells. They also provide a comprehensive and unique megabase-scale picture of the cellular epigenetic state. Thus normal differentiation involves reproducible changes in RT and transformation generally perturbs these, although the potential effects of altered RT on the properties of transformed cells remain largely unknown. A major challenge to interrogating these issues in human acute lymphoid leukemia (ALL) is the low proliferative activity of most of the cells, which may be further reduced in cryopreserved samples and difficult to overcome in vitro...
April 19, 2017: Experimental Hematology
https://www.readbyqxmd.com/read/28425714/prehydrated-one-electron-attachment-to-azido-modified-pentafuranoses-aminyl-radical-formation-rapid-h-atom-transfer-and-subsequent-ring-opening
#8
Mukesh Mudgal, Sunny Rishi, Daniel A Lumpuy, Keaton A Curran, Kathryn Lynn Verley, Adam J Sobczak, Thao P Dang, Natasha Sulimoff, Anil Kumar, Michael D Sevilla, Stanislaw F Wnuk, Amitava Adhikary
Methyl 2-azido-2-deoxy-α-D-lyxofuranoside (1a) and methyl 2-azido-2-deoxy-β-D-ribofuranoside (2) were prepared from D-xylose or D-arabinose, respectively. Employing ESR and DFT/B3LYP/6-31G* calculations, we investigated (i) aminyl radical (RNH•) formation and (ii) reaction pathways of RNH•. Prehydrated electron attachment to 1a and 2 at 77 K produced transient azide anion radical (RN3•¯) which reacts via rapid N2 loss at 77 K, forming nitrene anion radical (RN•¯). Rapid protonation of RN•¯ at 77 K formed RNH• and ¯OH...
April 20, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28423033/can-soda-ash-dumping-grounds-provide-replacement-habitats-for-digger-wasps-hymenoptera-apoidea-spheciformes
#9
Lucyna Twerd, Maciej Krzyżyński, Barbara Waldon-Rudzionek, Piotr Olszewski
BACKGROUND: Published sources document a loss of biodiversity at an extreme rate, mainly because natural and semi-natural ecosystems are becoming fragmented and isolated, thus losing their biological functions. These changes significantly influence biological diversity, which is a complex phenomenon that changes over time. Contemporary ecologists must therefore draw attention to anthropogenic replacement habitats and increase their conservation status. In our studies we show the positive role of soda ash dumping grounds as an alternative habitat for digger wasps, especially the thermophilic species...
2017: PloS One
https://www.readbyqxmd.com/read/28422194/field-induced-anomalous-spreading-oscillation-ejection-spinning-and-breaking-of-oil-droplets-on-a-strongly-slipping-water-surface
#10
Sunny Kumar, Bhaskarjyoti Sarma, Ahsok Kumar Dasmahapatra, Amaresh Dalal, Dipankar Narayan Basu, Dipankar Bandyopadhyay
Application of an electric field on an oil droplet floating on the surface of a deionized water bath showed interesting motions such as spreading, oscillation, and ejection. The electric field was generated by connecting a pointed platinum cathode at the top of the oil droplet and a copper anode coated with polymer at the bottom of the water layer. The experimental setup mimicked a conventional electrowetting setup with the exception that the oil was spread on a soft and deformable water isolator. While at relatively lower field intensities we observed spreading of the droplet, at intermediate field intensities the droplet oscillated around the platinum cathode, before ejecting out at a speed as high as ∼5 body lengths per second at even stronger field intensities...
April 19, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28417116/a-long-persistence-phosphor-tailored-quasi-solid-state-dye-sensitized-solar-cell-that-generates-electricity-in-sunny-and-dark-weathers
#11
Qunwei Tang, Min Wang, Zhongling Wang, Weiyin Sun, Ruoxu Shang
An all-weather quasi-solid-state dye-sensitized solar cell is built using a long persistence phosphor tailored mesoscopic TiO2 photoanode and a three-dimensional conducting polymer gel electrolyte. The so-called all-weather solar cell yields a maximum efficiency of 28.7% in the dark, making a promising photovoltaic revolutionary for state-of-the-art photovoltaics.
April 18, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28416323/review-of-coronary-subclavian-steal-syndrome
#12
REVIEW
Bennett Cua, Natasha Mamdani, David Halpin, Sunny Jhamnani, Sasanka Jayasuriya, Carlos Mena-Hurtado
The clinical benefits of using the left internal mammary artery (LIMA) to bypass the left anterior descending artery are well established making it the most frequently used conduit for coronary artery bypass surgery (CABG). Coronary subclavian steal syndrome (CSSS) occurs during left arm exertion when (1) the LIMA is used during bypass surgery and (2) there is a high grade (≥75%) left subclavian artery stenosis or occlusion proximal to the ostia of the LIMA resulting in "stealing" of the myocardial blood supply via retrograde flow up the LIMA graft to maintain left upper extremity perfusion...
April 14, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28403899/hepato-bronchial-fistula-secondary-to-perforated-sigmoid-diverticulitis-a-case-report
#13
Jun Sunny Yin, Shaylan Govind, Daniele Wiseman, Richard Inculet, Raymond Kao
BACKGROUND: Patients with diverticulitis are predisposed to hepatic abscesses via seeding through the portal circulation. Hepatic abscesses are well-documented sequelae of diverticulitis, however instances of progression to hepato-bronchial fistulization are rare. We present a case of diverticulitis associated with hepatic abscess leading to hepato-bronchial fistulization, which represents a novel disease course not yet reported in the literature. CASE PRESENTATION: A 61-year-old Caucasian man presented with a history of unintentional weight loss and dyspnea both at rest and with exertion...
April 13, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28400394/urethrocutaneous-fistula-mimicking-vesicocutaneous-fistula-a-rare-entity
#14
Ruchir Aeron, Apul Goel, Ashok Kumar Sokhal, Sunny Goel
Urethral fistulas arising from the anterior urethra usually open on the ventral aspect and are located in the penile, scrotal or perineal region. A diabetic 65-year-old man presented with suprapubic urinary fistula that was communicating with a dorsally located internal urethral opening located in the bulbar region. Such unusual fistula has not been described before.
April 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28397539/vitamin-d-status-and-cardiometabolic-risk-factors-across-latitudinal-gradient-in-iranian-adults
#15
Bahareh Nikooyeh, Zahra Abdollahi, Majid Hajifaraji, Hamid Alavi-Majd, Forouzan Salehi, Amir Hossein Yarparvar, Tirang R Neyestani
BACKGROUND: This study aimed to evaluate the vitamin D status in an adult population across latitudinal gradient and to investigate its possible associations with certain cardiometabolic risk factors. METHODS: A total of 1406 healthy subjects aged 19-60 years were randomly selected from six regions of Iran across latitudinal gradient from 29° N to 37.5° N. Anthropometric and biochemical assessments were performed. The combination of high body mass index (>25 kg/m(2)), low high-density lipoprotein cholesterol (< 40 mg/dl in males and < 50 mg/dl in females) and high triglycerides (> 150 mg/dl) was defined as cardiometabolic risk factors...
January 1, 2017: Nutrition and Health
https://www.readbyqxmd.com/read/28395707/development-and-validation-of-the-narrative-quality-assessment-tool
#16
Wonsun Sunny Kim, Cha-Nam Shin, Linda Kathryn Larkey, Denise J Roe
BACKGROUND AND PURPOSE: The use of storytelling in health promotion has grown over the past 2 decades, showing promise for moving people to initiate healthy behavior change. Given the increasingly prevalent role of storytelling in health promotion research and the need to more clearly identify what storytelling elements and mediators may better predict behavior change, there is a need to develop measures to specifically assess these factors in a cultural community context. The purpose of this study is to develop and preliminarily validate a narrative quality assessment tool for measuring elements of storytelling that are predicted to affect attitude and behavior change (i...
April 1, 2017: Journal of Nursing Measurement
https://www.readbyqxmd.com/read/28385637/trigger-factor-induced-nascent-chain-dynamics-changes-suggest-two-different-chaperone-nascent-chain-interactions-during-translation
#17
Jiří Koubek, Yi-Che Chang, Sunny Yao-Chen Yang, Joseph Jen-Tse Huang
Protein biogenesis is poorly understood due to the ribosome which perturbs measurement attempted on the ribosome-bound nascent chain (RNC). Investigating nascent chain dynamics may provide invaluable insight into the co-translational processes such as structure formation or interaction with a chaperone, e.g. the bacterial Trigger Factor (TF). In this study, we aim to establish a platform for studying nascent chain dynamics by exploring the local environment near the fluorescent dye on site-specifically labeled RNCs with time-resolved fluorescence anisotropy...
April 3, 2017: Journal of Molecular Biology
https://www.readbyqxmd.com/read/28384349/neutrophils-and-ly6chi-monocytes-collaborate-in-generating-an-optimal-cytokine-response-that-protects-against-pulmonary-legionella-pneumophila-infection
#18
Cierra N Casson, Jessica L Doerner, Alan M Copenhaver, Jasmine Ramirez, Alicia M Holmgren, Mark A Boyer, Ingharan J Siddarthan, Sara H Rouhanifard, Arjun Raj, Sunny Shin
Early responses mounted by both tissue-resident and recruited innate immune cells are essential for host defense against bacterial pathogens. In particular, both neutrophils and Ly6Chi monocytes are rapidly recruited to sites of infection. While neutrophils and monocytes produce bactericidal molecules, such as reactive nitrogen and oxygen species, both cell types are also capable of synthesizing overlapping sets of cytokines important for host defense. Whether neutrophils and monocytes perform redundant or non-redundant functions in the generation of anti-microbial cytokine responses remains elusive...
April 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28382539/air-pollution-and-children-s-asthma-related-emergency-hospital-visits-in-southeastern-france
#19
Julie Mazenq, Jean-Christophe Dubus, Jean Gaudart, Denis Charpin, Antoine Nougairede, Gilles Viudes, Guilhem Noel
Children's asthma is multifactorial. Environmental factors like air pollution exposure, meteorological conditions, allergens, and viral infections are strongly implicated. However, place of residence has rarely been investigated in connection with these factors. The primary aim of our study was to measure the impact of particulate matter (PM), assessed close to the children's homes, on asthma-related pediatric emergency hospital visits within the Bouches-du-Rhône area in 2013. In a nested case-control study on 3- to 18-year-old children, each control was randomly matched on the emergency room visit day, regardless of hospital...
April 5, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28378544/effects-of-cyp2c19-genetic-polymorphisms-on-pk-pd-responses-of-omeprazole-in-korean-healthy-volunteers
#20
Sunny Park, Yang Jin Hyun, Yu Ran Kim, Ju Hyun Lee, Sunae Ryu, Jeong Mi Kim, Woo Yong Oh, Han Sung Na, Jong Gu Lee, Doo Won Seo, In Yeong Hwang, Zewon Park, In Jin Jang, Jaeseong Oh, Seung Eun Choi
The aim of this study was to examine the effects of CYP2C19*2 and *3 genetic polymorphisms on omeprazole pharmacokinetic (PK) and pharmacodynamic (PD) responses. Twenty-four healthy Korean volunteers were enrolled and given 20 mg omeprazole orally once daily for 8 days. The genotypes of CYP2C19 single nucleotide polymorphisms (SNPs) (*2, *3, and *17) were screened. The plasma concentrations of omeprazole, omeprazole sulfone, and 5-hydroxy (5-OH) omeprazole were determined by liquid chromatography with tandem mass spectrometry (LC-MS/MS)...
May 2017: Journal of Korean Medical Science
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