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Ruaim A Muaygil
Advances in reproductive medicine have provided new, and much needed, hope for millions of people struggling with infertility. Gestational surrogacy is one such development that has been gaining popularity with infertile couples, especially those unable to benefit from other reproductive procedures such as In Vitro Fertilization. For many Muslim couples, however, surrogacy remains a nonviable option. Islamic scholars have deemed the procedure incompatible with Islam and have prohibited its use. This paper examines the arguments presented for proscribing surrogacy arrangements in Sunni Islam in particular...
October 20, 2016: Developing World Bioethics
Sunny S Kim, Rahul Rawat, Edina M Mwangi, Roman Tesfaye, Yewelsew Abebe, Jean Baker, Edward A Frongillo, Marie T Ruel, Purnima Menon
Optimal breastfeeding (BF) practices in Ethiopia are far below the government's targets, and complementary feeding practices are poor. The Alive & Thrive initiative aimed to improve infant and young child feeding (IYCF) practices through large-scale implementation of social and behavior change communication interventions in four regions of Ethiopia. The study assessed the effects of the interventions on IYCF practices and anthropometry over time in two regions-Southern Nations, Nationalities and Peoples Region and Tigray...
2016: PloS One
Dalvir Gill, Sunny Pattar, Liu Kan
No abstract text is available yet for this article.
October 12, 2016: American Journal of Therapeutics
Rose G Radin, Lindsey A Sjaarda, Neil J Perkins, Robert M Silver, Zhen Chen, Laurie L Lesher, Noya Galai, Jean Wactawski-Wende, Sunni L Mumford, Enrique F Schisterman
CONTEXT: Among women with a single, recent pregnancy loss, daily preconception low-dose aspirin (LDA) increased the live birth rate with no effect on pregnancy loss. The mechanism underlying this effect is unclear, but it may work through ovulation. OBJECTIVE: We estimated the effect of LDA on the per-cycle risk of anovulation among eumenorrheic women. DESIGN: The Effects of Aspirin in Gestation and Reproduction trial, a multi-center, randomized, double-blind, placebo-controlled trial of daily LDA on reproductive outcomes...
October 18, 2016: Journal of Clinical Endocrinology and Metabolism
Alexander H Fischer, Timothy S Wang, Gayane Yenokyan, Sewon Kang, Anna L Chien
Importance: Indoor tanning is prevalent among young adults and women and is associated with increased risk of melanoma. Evidence suggests that indoor tanners may be more inclined to adopt poor photoprotective practices that further increase their risk of skin cancer; however, gaps in the literature exist in young adults and by indoor tanning frequency. Objective: To examine the association between indoor tanning frequency and behaviors related to skin cancer prevention and to investigate whether these associations vary by age group or sex...
October 12, 2016: JAMA Dermatology
Khalil Salameh, Najah Saleh Ali Al-Janahi, Adriana M Reedy, Adekunle Dawodu
PURPOSE: Evaluation of vitamin D (vD) status and risk factors for low vD among breastfeeding mother-infant dyads in a population at high risk for vD deficiency. SUBJECTS AND METHODS: We measured serum 25-hydroxyvitamin D (25(OH)D) and parathyroid hormone at 1 month postpartum in 60 consecutive exclusively breastfeeding Arab mother-infant dyads enrolled in a high dose vD supplementation study to prevent vD deficiency in Doha, Qatar, (latitude 25°N) during summer months...
2016: International Journal of Women's Health
James Kwan, Libby Stein, Sean Delshad, Sunny Johl, Hannah Park, Bibiana Martinez, Lindsey Topp, Brennan M R Spiegel
No abstract text is available yet for this article.
October 11, 2016: American Journal of Gastroenterology
Rafael Bilbao-Calabuig, Felix González-López, Ferrer Amparo, Gemma Alvarez, Sunni R Patel, Fernando Llovet-Osuna
PURPOSE: To investigate the visual outcomes between mix-and-match bifocal intraocular lenses (IOLs) (ReSTOR +2.50 and +3.00 diopters [D]; Alcon Laboratories, Inc., Fort Worth, TX) versus bilateral implantation of a trifocal IOL (FineVision; PhysIOL, Liège, Belgium). METHODS: Twenty-three patients (average age: 56.3 ± 6.9 years; range: 45 to 71 years) referred for lens phacoemulsification and IOL implantation were included in this study. Patients were randomly assigned to two groups...
October 1, 2016: Journal of Refractive Surgery
Mervyn Davies, Sunny Cho, David Spink, Ron Pauls, Michael Desilets, Yan Shen, Kanwardeep Bajwa, Reid Person
In the Athabasca oil sands region (AOSR) of Northern Alberta, the dry deposition of sulphur and nitrogen compounds represents a major fraction of total (wet plus dry) deposition due to oil sands emissions. The leaf area index (LAI) is a critical parameter that affects the dry deposition of these gaseous and particulate compounds to the surrounding boreal forest canopy. For this study, LAI values based on Moderate Resolution Imaging Spectroradiometer satellite imagery were obtained and compared to ground-based measurements, and two limitations with the satellite data were identified...
October 4, 2016: Journal of Environmental Management
Innocent S Ike, Iakovos Sigalas, Sunny E Iyuke
The influence of different charging current densities, charging times and several structural designs on symmetric electrochemical capacitor (EC) performance, including capacitance, energy density and power density, has been investigated via modelling and simulation. Understanding the effects of different operating conditions and structural design variables on a capacitor's performance will guide in the optimal design and fabrication of high performance ECs. The operating conditions and design configurations examined were charging current density, charging times, electrode and electrolyte effective conductivity, electrode thickness and electrode porosity...
October 6, 2016: Physical Chemistry Chemical Physics: PCCP
Shinhee Park, Sunny Lihua Cheng, Julia Yue Cui
Intestine is responsible for the biotransformation of many orally-exposed chemicals. The constitutive androstane receptor (CAR/Nr1i3) is known to up-regulate many genes encoding drug-metabolizing enzymes and transporters (drug-processing genes/DPGs) in liver, but less is known regarding its effect in intestine. Sixty-day-old wild-type and Car(-/-) mice were administered the CAR-ligand TCPOBOP or vehicle once daily for 4 days. In wild-type mice, Car mRNA was down-regulated by TCPOBOP in liver and duodenum. Car(-/-) mice had altered basal intestinal expression of many DPGs in a section-specific manner...
September 2016: Acta Pharmaceutica Sinica. B
Stavros Stavrakis, Julie A Stoner, Joel Kardokus, Paul J Garabelli, Sunny S Po, Ralph Lazzara
PURPOSE: We hypothesized that intermittent anticoagulation based on daily rhythm monitoring using the novel oral anticoagulants (NOACs) is feasible and safe among patients with paroxysmal atrial fibrillation (AF). METHODS: Patients with paroxysmal AF and ≥1 risk factors for stroke were randomized to either intermittent or continuous anticoagulation. Those in the intermittent group were instructed to transmit a daily ECG using an iPhone-based rhythm monitoring device...
October 1, 2016: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Sunni A Barnes, Jan Compton, Margaret Saldaña, Kristen M Tecson, Chizuko Hastings, Donald A Kennerly
Improving the quality of patient care requires a culture attuned to safety. We describe the development, implementation, and psychometric evaluation of the Attitudes and Practices of Patient Safety Survey (APPSS) within the Baylor Scott & White Health system. The APPSS was designed to enable safety culture data to be collected and aggregated at the unit level to identify high-priority needs. The survey, with 27 Likert-scale core questions divided into 4 concept domains and 2 open-ended questions, was administered electronically to employees with direct patient care responsibilities (n = 16,950)...
October 2016: Proceedings of the Baylor University Medical Center
Steven R Brant, David T Okou, Claire L Simpson, David J Cutler, Talin Haritunians, Jonathan P Bradfield, Pankaj Chopra, Jarod Prince, Ferdouse Begum, Archana Kumar, Chengrui Huang, Suresh Venkateswaran, Lisa W Datta, Zhi Wei, Kelly Thomas, Lisa J Herrinton, Jan-Micheal A Klapproth, Antonio J Quiros, Jenifer Seminerio, Zhenqiu Liu, Jonathan S Alexander, Robert N Baldassano, Sharon Dudley-Brown, Raymond K Cross, Themistocles Dassopoulos, Lee A Denson, Tanvi A Dhere, Gerald W Dryden, John S Hanson, Jason K Hou, Sunny Z Hussain, Jeffrey S Hyams, Kim L Isaacs, Howard Kader, Michael D Kappelman, Jeffry Katz, Richard Kellermayer, Barbara S Kirschner, John F Kuemmerle, John H Kwon, Mark Lazarev, Ellen Li, David Mack, Peter Mannon, Dedrick E Moulton, Rodney D Newberry, Bankole O Osuntokun, Ashish S Patel, Shehzad A Saeed, Stephan R Targan, John F Valentine, Ming-Hsi Wang, Martin Zonca, John D Rioux, Richard H Duerr, Mark S Silverberg, Judy H Cho, Hakon Hakonarson, Michael E Zwick, Dermot P B McGovern, Subra Kugathasan
BACKGROUND & AIMS: The inflammatory bowel diseases (IBD) ulcerative colitis (UC) and Crohn's disease (CD) cause significant morbidity and are increasing in prevalence among all populations, including African Americans. More than 200 susceptibility loci have been identified in populations of predominantly European ancestry, but few loci have been associated with IBD in other ethnicities. METHODS: We performed 2 high-density, genome-wide scans comprising 2345 cases of African Americans with IBD (1646 with CD, 583 with UC, and 116 inflammatory bowel disease unclassified [IBD-U]) and 5002 individuals without IBD (controls, identified from the Health Retirement Study and Kaiser Permanente database)...
September 28, 2016: Gastroenterology
Steffi Sunny, George Cheng, Daniel Daniel, Peter Lo, Sebastian Ochoa, Caitlin Howell, Nicolas Vogel, Adnan Majid, Joanna Aizenberg
Camera-guided instruments, such as endoscopes, have become an essential component of contemporary medicine. The 15-20 million endoscopies performed every year in the United States alone demonstrate the tremendous impact of this technology. However, doctors heavily rely on the visual feedback provided by the endoscope camera, which is routinely compromised when body fluids and fogging occlude the lens, requiring lengthy cleaning procedures that include irrigation, tissue rubbing, suction, and even temporary removal of the endoscope for external cleaning...
September 29, 2016: Proceedings of the National Academy of Sciences of the United States of America
Sunny Tian, Karina Bertelsmann, Linda Yu, Shuying Sun
Heterogeneous DNA methylation patterns are linked to tumor growth. In order to study DNA methylation heterogeneity patterns for breast cancer cell lines, we comparatively study four metrics: variance, I (2) statistic, entropy, and methylation state. Using the categorical metric methylation state, we select the two most heterogeneous states to identify genes that directly affect tumor suppressor genes and high- or moderate-risk breast cancer genes. Utilizing the Gene Set Enrichment Analysis software and the ConsensusPath Database visualization tool, we generate integrated gene networks to study biological relations of heterogeneous genes...
2016: Cancer Informatics
Enrique F Schisterman, Neil J Perkins, Sunni L Mumford, Katherine A Ahrens, Emily M Mitchell
BACKGROUND: Correlated data are ubiquitous in epidemiologic research, particularly in nutritional and environmental epidemiology where mixtures of factors are often studied. Our objectives are to demonstrate how highly correlated data arise in epidemiologic research and provide guidance, using a directed acyclic graph approach, on how to proceed analytically when faced with highly correlated data. METHODS: We identified three fundamental structural scenarios in which high correlation between a given variable and the exposure can arise: intermediates, confounders, and colliders...
August 26, 2016: Epidemiology
Richard Zhang, Gabriel Rudd-Barnard, Lindsay M Szafranski, Ian D Dworkin, Sunny Sharma, Edward Pang, Dixie R Aragaki, Aashna Basu
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
Anupam Sinha, Sunny Gupta, Mitesh Patel
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
Marilou P Sison-Mangus, Sunny Jiang, Raphael M Kudela, Sanjin Mehic
Pseudo-nitzschia blooms often occur in coastal and open ocean environments, sometimes leading to the production of the neurotoxin domoic acid that can cause severe negative impacts to higher trophic levels. Increasing evidence suggests a close relationship between phytoplankton bloom and bacterial assemblages, however, the microbial composition and succession during a bloom process is unknown. Here, we investigate the bacterial assemblages before, during and after toxic and non-toxic Pseudo-nitzschia blooms to determine the patterns of bacterial succession in a natural bloom setting...
2016: Frontiers in Microbiology
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