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https://www.readbyqxmd.com/read/28818939/preventing-mussel-adhesion-using-lubricant-infused-materials
#1
Shahrouz Amini, Stefan Kolle, Luigi Petrone, Onyemaechi Ahanotu, Steffi Sunny, Clarinda N Sutanto, Shawn Hoon, Lucas Cohen, James C Weaver, Joanna Aizenberg, Nicolas Vogel, Ali Miserez
Mussels are opportunistic macrofouling organisms that can attach to most immersed solid surfaces, leading to serious economic and ecological consequences for the maritime and aquaculture industries. We demonstrate that lubricant-infused coatings exhibit very low preferential mussel attachment and ultralow adhesive strengths under both controlled laboratory conditions and in marine field studies. Detailed investigations across multiple length scales-from the molecular-scale characterization of deposited adhesive proteins to nanoscale contact mechanics to macroscale live observations-suggest that lubricant infusion considerably reduces fouling by deceiving the mechanosensing ability of mussels, deterring secretion of adhesive threads, and decreasing the molecular work of adhesion...
August 18, 2017: Science
https://www.readbyqxmd.com/read/28817624/ephb4-ephrinb2-therapeutics-in-rhabdomyosarcoma
#2
Matthew E Randolph, Megan M Cleary, Zia Bajwa, Matthew N Svalina, Michael C Young, Atiya Mansoor, Pali Kaur, Carol J Bult, Martin W Goros, Joel E Michalek, Sunny Xiang, James Keck, Valery Krasnoperov, Parkash Gill, Charles Keller
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma affecting children and is often diagnosed with concurrent metastases. Unfortunately, few effective therapies have been discovered that improve the long-term survival rate for children with metastatic disease. Here we determined effectiveness of targeting the receptor tyrosine kinase, EphB4, in both alveolar and embryonal RMS either directly through the inhibitory antibody, VasG3, or indirectly by blocking both forward and reverse signaling of EphB4 binding to EphrinB2, cognate ligand of EphB4...
2017: PloS One
https://www.readbyqxmd.com/read/28813316/perspectives-on-the-conceptualization-of-the-dissociative-subtype-of-ptsd-and-implications-for-treatment
#3
REVIEW
Sunny J Dutra, Erika J Wolf
A dissociative subtype of PTSD was added to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) to denote a distinct presentation of PTSD marked by symptoms of derealization and depersonalization. The subtype has brought renewed interest in the conceptualization of dissociation in PTSD, and raised questions about its treatment. We review the evidence for two models of PTSD-related dissociative symptoms and the treatment approaches that align with each. We find support for the contributions of biologically-based trait-level factors to dissociation, and suggest that empirically supported treatments for PTSD demonstrate efficacy for patients with the subtype...
April 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28805126/using-culture-and-psychology-to-counter-the-taliban-s-violent-narratives
#4
Neil Krishan Aggarwal
Scholars, politicians, and policy-makers have increasingly pointed to the role of narratives in recruiting militants and justifying violence, highlighting the need for counter-narratives that promote peace. However, few have offered concrete guidelines on how to construct counter-narratives. This exploratory study uses prototype theory from social psychology to analyse Taliban narratives written in Arabic on the historical figure Maḥmūd of Ghaznī (971-1030), who is portrayed as a figure worthy of emulation...
August 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/28803559/rethinking-the-idea-of-late-autism-spectrum-disorder-onset
#5
Elizabeth C Bacon, Eric Courchesne, Cynthia Carter Barnes, Debra Cha, Sunny Pence, Laura Schreibman, Aubyn C Stahmer, Karen Pierce
A common theory of autism spectrum disorder (ASD) symptom onset includes toddlers who do not display symptoms until well after age 2, which are termed late-onset ASD cases. Objectives were to analyze differences in clinical phenotype between toddlers identified as ASD at initial evaluations (early diagnosed) versus those initially considered nonspectrum, then later identified as ASD (late diagnosed). Two hundred seventy-three toddlers recruited from the general population based on a failed developmental screening form or parent or physician concerns were followed longitudinally from 12 months and identified as early- and late-diagnosed cases of ASD, language delayed, or typically developing...
August 14, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28797427/low-level-tragus-stimulation-for-the-treatment-of-ischemia-and-reperfusion-injury-in-patients-with-st-segment-elevation-myocardial-infarction-a-proof-of-concept-study
#6
Lilei Yu, Bing Huang, Sunny S Po, Tuantuan Tan, Menglong Wang, Liping Zhou, Guannan Meng, Shenxu Yuan, Xiaoya Zhou, Xuefei Li, Zhuo Wang, Songyun Wang, Hong Jiang
OBJECTIVES: The aim of this study was to investigate whether low-level tragus stimulation (LL-TS) treatment could reduce myocardial ischemia-reperfusion injury in patients with ST-segment elevation myocardial infarction (STEMI). BACKGROUND: The authors' previous studies suggested that LL-TS could reduce the size of myocardial injury induced by ischemia. METHODS: Patients who presented with STEMI within 12 h of symptom onset, treated with primary percutaneous coronary intervention, were randomized to the LL-TS group (n = 47) or the control group (with sham stimulation [n = 48])...
August 14, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28789757/unidimensional-and-bidimensional-approaches-to-measuring-acculturation
#7
Cha-Nam Shin, Michael Todd, Kyungeh An, Wonsun Sunny Kim
BACKGROUND AND PURPOSE: Researchers easily overlook the complexity of acculturation measurement in research. This study is to elaborate the shortcomings of unidimensional approaches to conceptualizing acculturation and highlight the importance of using bidimensional approaches in health research. METHODS: We conducted a secondary data analysis on acculturation measures and eating habits obtained from 261 Korean American adults in a Midwestern city. RESULTS: Bidimensional approaches better conceptualized acculturation and explained more of the variance in eating habits than did unidimensional approaches...
August 1, 2017: Journal of Nursing Measurement
https://www.readbyqxmd.com/read/28789684/blood-lead-cadmium-and-mercury-in-relation-to-homocysteine-and-c-reactive-protein-in-women-of-reproductive-age-a-panel-study
#8
Anna Z Pollack, Sunni L Mumford, Lindsey Sjaarda, Neil J Perkins, Farah Malik, Jean Wactawski-Wende, Enrique F Schisterman
BACKGROUND: To examine the relationship between cadmium, lead, and mercury concentrations with high-sensitivity C-reactive protein (hs-CRP) and homocysteine in women. METHODS: Metals were measured at enrollment in whole blood. Homocysteine and hs-CRP were measured in one (N = 9) or two (N = 250) menstrual cycles up to 3 and 8 times per cycle, respectively. Linear mixed models with inverse probability of exposure weights to account for time varying confounding were used and models were stratified by dietary and serum vitamin status (dietary: vitamin B6, B12, folate; serum: folate)...
August 8, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28783475/prevalence-and-management-of-coracoid-fracture-sustained-during-sporting-activities-and-time-to-return-to-sport-a-systematic-review
#9
Derrick M Knapik, Sunny H Patel, Robert J Wetzel, James E Voos
BACKGROUND: Coracoid fractures sustained during sporting activities are rare. Previous reports are limited to individual case reports, small case series, and retrospective analyses. PURPOSE: To systematically review the literature and identify coracoid fractures sustained during sporting activities to determine fracture prevalence, sporting activities/mechanisms, management, and time to return to sport. STUDY DESIGN: Systematic review. METHODS: A systematic review was conducted investigating all studies in the literature published between January 1970 and April 2017 that reported on athletes sustaining coracoid fractures during sporting activity...
August 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28782316/rediscovering-chirality-role-of-s-metoprolol-in-cardiovascular-disease-management
#10
Jagdish C Mohan, Siddharth N Shah, Sunny Chinchansurkar, Arindam Dey, Rishi Jain
BACKGROUND: The process of drug discovery and development today encompass a myriad of paths for bringing a new therapeutic molecule that has minimal adverse effects and of optimal use to the patient. Chirality was proposed in the direction of providing a purer and safer form of drug [Ex- cetrizine and levocetrizine]. Decades have passed since the introduction of this concept and numerous chiral molecules are in existence in therapeutics, yet somehow this concept has been ignored. This review aims to rediscover the ignored facts about chirality, its benefits and clear some common myths considering the example of S-Metoprolol in the management of Hypertension and other cardiovascular diseases...
June 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28770075/tropical-soils-degraded-by-slash-and-burn-cultivation-can-be-recultivated-when-amended-with-ashes-and-compost
#11
Justine Marie Gay-des-Combes, Clara Sanz Carrillo, Bjorn Jozef Maria Robroek, Vincent Eric Jules Jassey, Robert Thomas Edmund Mills, Muhammad Saleem Arif, Leia Falquet, Emmanuel Frossard, Alexandre Buttler
In many tropical regions, slash-and-burn agriculture is considered as a driver of deforestation; the forest is converted into agricultural land by cutting and burning the trees. However, the fields are abandoned after few years because of yield decrease and weed invasion. Consequently, new surfaces are regularly cleared from the primary forest. We propose a reclamation strategy for abandoned fields allowing and sustaining re-cultivation. In the dry region of south-western Madagascar, we tested, according to a split-plot design, an alternative selective slash-and-burn cultivation technique coupled with compost amendment on 30-year-old abandoned fields...
July 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28766226/nipple-sparing-mastectomy-pitfalls-and-challenges
#12
Suzanne B Coopey, Sunny D Mitchell
No abstract text is available yet for this article.
August 1, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28765474/mucosal-microbiome-dysbiosis-in-gastric-carcinogenesis
#13
Olabisi Oluwabukola Coker, Zhenwei Dai, Yongzhan Nie, Guijun Zhao, Lei Cao, Geicho Nakatsu, William Kk Wu, Sunny Hei Wong, Zigui Chen, Joseph J Y Sung, Jun Yu
OBJECTIVES: We aimed to characterise the microbial changes associated with histological stages of gastric tumourigenesis. DESIGN: We performed 16S rRNA gene analysis of gastric mucosal samples from 81 cases including superficial gastritis (SG), atrophic gastritis (AG), intestinal metaplasia (IM) and gastric cancer (GC) from Xi'an, China, to determine mucosal microbiome dysbiosis across stages of GC. We validated the results in mucosal samples of 126 cases from Inner Mongolia, China...
August 1, 2017: Gut
https://www.readbyqxmd.com/read/28759614/pilot-study-of-a-novel-classroom-designed-to-prevent-myopia-by-increasing-children-s-exposure-to-outdoor-light
#14
Zhongqiang Zhou, Tingting Chen, Mengrui Wang, Ling Jin, Yongyi Zhao, Shangji Chen, Congyao Wang, Guoshan Zhang, Qilin Wang, Qiaoming Deng, Yubo Liu, Ian G Morgan, Mingguang He, Yizhi Liu, Nathan Congdon
We sought to assess light characteristics and user acceptability of a prototype Bright Classroom (BC), designed to prevent children's myopia by exposing them to light conditions resembling the outdoors. Conditions were measured throughout the school year in the glass-constructed BC, a traditional classroom (TC) and outdoors. Teachers and children completed user questionnaires, and children rated reading comfort at different light intensities. A total of 230 children (mean age 10.2 years, 57.4% boys) and 13 teachers (36...
2017: PloS One
https://www.readbyqxmd.com/read/28758850/a-picture-based-carbohydrate-counting-resource-for-somalis
#15
Muna Sunni, Carol Brunzell, Jennifer Kyllo, Loren Purcell, Phillip Plager, Antoinette Moran
Objective Carbohydrate counting is essential for effective management of type 1 diabetes (T1D). Somali diet-specific carbohydrate-counting references are lacking, creating an additional barrier to effective diabetes control. We developed a picture-based carbohydrate-counting resource for Somalis with T1D. Methods Traditional Somali foods were selected using a variety of methods. Serving sizes and carbohydrate calculations were tabulated using the United States Department of Agriculture National Nutrient Database for Standard Reference...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28756154/photodynamic-therapy-for-actinic-keratosis-is-the-european-consensus-protocol-for-daylight-pdt-superior-to-conventional-protocol-for-aktilite-cl-128-pdt
#16
Anne-Sophie Vignion-Dewalle, Gregory Baert, Elise Thecua, Claire Vicentini, Laurent Mortier, Serge Mordon
BACKGROUND: Topical photodynamic therapy (PDT) is an established treatment modality for various dermato-oncologic conditions. In Europe, initially requiring irradiation with red light, PDT of actinic keratosis (AK) can now also be carried out with exposure to daylight that has been clinically proven to be as effective as and less painful than red light. OBJECTIVES: In this paper, we propose a comparison between the conventional protocol for Aktilite CL 128 (red light source) PDT and the European consensus protocol for daylight PDT - with the exposure is assumed to be performed during either a clear sunny day or an overcast day - in the treatment of AK with methyl aminolevulinate through a mathematical modeling...
July 22, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28749979/attitudes-and-decision-making-about-early-infant-versus-early-adolescent-male-circumcision-demand-side-insights-for-sustainable-hiv-prevention-strategies-in-zambia-and-zimbabwe
#17
Sema K Sgaier, Sunny Sharma, Maria Eletskaya, Ram Prasad, Owen Mugurungi, Bushimbwa Tambatamba, Getrude Ncube, Sinokuthemba Xaba, Alice Nanga, Sehlulekile Gumede-Moyo, Steve Kretschmer
As countries approach their scale-up targets for the voluntary medical male circumcision program for HIV prevention, they are strategizing and planning for the sustainability phase to follow. Global guidance recommends circumcising adolescent (below 14 years) and/or early infant boys (aged 0-60 days), and countries need to consider several factors before prioritizing a cohort for their sustainability phase. We provide community and healthcare provider-side insights on attitudes and decision-making process as a key input for this strategic decision in Zambia and Zimbabwe...
2017: PloS One
https://www.readbyqxmd.com/read/28749780/the-prevalence-of-extended-spectrum-beta-lactamase-producing-multidrug-resistant-escherichia-coli-in-poultry-chickens-and-variation-according-to-farming-practices-in-punjab-india
#18
Charles H Brower, Siddhartha Mandal, Shivdeep Hayer, Mandeep Sran, Asima Zehra, Sunny J Patel, Ravneet Kaur, Leena Chatterjee, Savita Mishra, B R Das, Parminder Singh, Randhir Singh, J P S Gill, Ramanan Laxminarayan
BACKGROUND: Agricultural use of antimicrobials in subtherapeutic concentrations is increasing in response to the rising demand for food animal products worldwide. In India, the use of antimicrobials in food animal production is unregulated. Research suggests that many clinically important antimicrobials are used indiscriminately. This is the largest study to date in India that surveys poultry production to test for antimicrobial resistance and the occurrence of extended-spectrum (ESBLs) modulated by farming and managerial practices...
July 20, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28747231/different-patient-satisfaction-levels-between-the-first-and-second-knee-in-the-early-stage-after-simultaneous-bilateral-total-knee-arthroplasty-tka-a-comparison-between-subjective-and-objective-outcome-assessments
#19
Shuai Huang, Xing Li, Yubo Tang, Sunny Stiphan, Bin Yan, Peiheng He, Dongliang Xu
BACKGROUND: Simultaneous bilateral total knee arthroplasty (TKA) is an effective treatment option and safe for properly selected patients. The purpose of this study was to evaluate whether patients have different satisfaction levels between the first and second knee in the early stage after simultaneous bilateral TKA. METHODS: We retrospectively reviewed 46 patients who underwent simultaneous bilateral TKA by a single surgeon in our department between March 2013 and March 2015...
July 26, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28745631/integration-of-miniaturized-solid-phase-extraction-and-lc-ms-ms-detection-of-3-nitrotyrosine-in-human-urine-for-clinical-applications
#20
Xiaoguang Sunny Li, Shu Li, Melissa Ahrens, Gottfried Kellermann
Free 3-nitrotyrosine (3-NT) has been extensively used as a possible biomarker for oxidative stress. Increased levels of 3-NT have been reported in a wide variety of pathological conditions. However, existing methods lack the sufficient sensitivity and/or specificity necessary to measure the low endogenous level of 3-NT reliably and are too cumbersome for clinical applications. Hence, analytical improvement is urgently needed to accurately quantify the levels of 3-NT and verify the role of 3-NT in pathological conditions...
July 14, 2017: Journal of Visualized Experiments: JoVE
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