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Changfeng Sun, Yu Liu, Huiming Song, Qiufang Cai, Qiang Li, Lu Wang, Ruochen Mei, Congxi Fang
Sunshine is as essential as temperature and precipitation for tree growth, but sunshine duration reconstructions based on tree rings have not yet been conducted in China. In this study, we presented a 497-year sunshine duration reconstruction for the southeastern Tibetan Plateau using a width chronology of Abies forrestii from the central Hengduan Mountains. The reconstruction accounted for 53.5% of the variance in the observed sunshine during the period of 1961-2013 based on a stable and reliable linear regression...
February 14, 2018: Science of the Total Environment
JingJing Wu, Swei Sunny Hann
Nasopharyngeal carcinoma (NPC) is one of the most common cancers originating in the nasopharynx and occurring at high frequency in South-eastern Asia and North Africa. Long non-coding RNAs (lncRNAs) are a class of non-protein-coding RNA molecules and key regulators of developmental, physiological, and pathological processes in humans. Emerging studies have shown that lncRNAs play critical roles in tumorgenicity and cancer prognosis. With the development of deep sequencing analyses, an extensive amount of functional lncRNAs have been discovered in nasopharyngeal carcinoma tissues and cell lines...
February 9, 2018: Cellular Physiology and Biochemistry
Peter J Hotez
No abstract text is available yet for this article.
February 2018: PLoS Neglected Tropical Diseases
Adarsh B Vasista, Ravi P N Tripathi, Shailendra K Chaubey, Sunny Tiwari, G V Pavan Kumar
Vertical nanowires facilitate an innovative mechanism to channel the optical field in the orthogonal direction and act as a nanoscale light source. Subwavelength, vertically oriented nanowire platforms, both of plasmonic and semiconducting variety, can facilitate interesting far-field emission profiles and potentially carry orbital angular momentum states. Motivated by these prospects, in this Letter, we show how a hybrid plasmonic-organic platform can be harnessed to engineer far-field radiation. The system that we have employed is an organic nanowire made of diaminoanthroquinone grown on a plasmonic gold film...
February 15, 2018: Optics Letters
William K K Wu, Rui Sun, Tao Zuo, Yuanyuan Tian, Zhirong Zeng, Jeffery Ho, Justin C Y Wu, Francis K L Chan, Matthew T V Chan, Jun Yu, Joseph J Y Sung, Sunny H Wong, Maggie H Wang, Siew C Ng
The incidence of Crohn's disease is increasing in many Asian countries, but considerable differences in genetic susceptibility have been reported between Western and Asian populations. This study aimed to fine-map 23 previously reported Crohn's disease genes and identify their interactions in the Chinese population by Illumina-based targeted capture sequencing. Our results showed that the genetic polymorphism A>G at rs144982232 in MST1 showed the most significant association (P = 1.78 × 10-5; odds ratio = 4...
February 14, 2018: Journal of Cellular and Molecular Medicine
Alexis Autour, Sunny C Y Jeng, Adam D Cawte, Amir Abdolahzadeh, Angela Galli, Shanker S S Panchapakesan, David Rueda, Michael Ryckelynck, Peter J Unrau
Despite having many key roles in cellular biology, directly imaging biologically important RNAs has been hindered by a lack of fluorescent tools equivalent to the fluorescent proteins available to study cellular proteins. Ideal RNA labelling systems must preserve biological function, have photophysical properties similar to existing fluorescent proteins, and be compatible with established live and fixed cell protein labelling strategies. Here, we report a microfluidics-based selection of three new high-affinity RNA Mango fluorogenic aptamers...
February 13, 2018: Nature Communications
Emmanuel Owie, Bosede Bukola Afolabi
We aimed to determine the prevalence of Vitamin D deficiency among pregnant women and their newborns in order to make recommendations for Vitamin D supplementation, if necessary. It was a cross-sectional study carried out over a period of 12 months. Information such as use of Vitamin D supplements, number of daytime hours spent outdoors and dressing style was obtained from 166 pregnant women in Lagos, Nigeria; maternal and cord blood 25(OH)D concentration was determined using ELISA. The prevalence of Vitamin D deficiency (<20 ng/mL) in the mothers and newborns was 4...
February 13, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
Sunny Gupta, Sharmila N Shirodkar, Daniel Kaplan, Venkataraman Swaminathan, Boris I Yakobson
Optical spectroscopy (OS) techniques are often coupled with first-principles density functional theoretical (DFT) calculations for determining the precise influence of defects on the electronic and structural properties of two-dimensional (2D) transition metal dichalcogenides. Such calculations are carried out presuming there is little or no effect of vibrational transitions on the observed electronic spectrum. However, if the effect of change in vibrational energy (Franck Condon (FC) shift) associated with such a transition is large, it could possibly lead to a different origin for the observed peak...
February 12, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Suchi Chawla, Dilip J Patel, Sunny R Patel, Ravi L Kalasariya, Paresh G Shah
A field experiment was conducted to estimate residue persistence of fluopyram and its metabolite benzamide in cucumber fruits and soil and their risk assessment in humans and soil environment. Fluopyram (Kafka, 400 SC) was applied as soil drench twice at the interval of 15 days at the rate of 250 (standard dose) and 500 (double dose) g a.i. ha-1 (active ingredient per hectare). Cucumber fruits were collected at 0 (1 h), 1, 3, 5, 7, 10, 15, 20, 30, 40 and 50 days after second application. Soil samples were collected on 15th day after second application...
February 10, 2018: Environmental Science and Pollution Research International
Lindsey A Sjaarda, Sunni L Mumford, Daniel L Kuhr, Tiffany L Holland, Robert M Silver, Torie C Plowden, Neil J Perkins, Enrique F Schisterman
OBJECTIVE: To examine whether higher T and/or antimüllerian hormone (AMH) was associated with anovulation, time to pregnancy (TTP), or pregnancy loss risk among healthy, fecund women without diagnosed polycystic ovary syndrome. DESIGN: Prospective cohort study conducted as a secondary analysis from the Effects of Aspirin in Gestation and Reproduction randomized trial. SETTING: University medical centers. PATIENT(S): A total of 1,198 healthy, eumenorrheic women aged 18-40 years attempting spontaneous pregnancy with one to two prior pregnancy losses were included...
February 7, 2018: Fertility and Sterility
Lilei Yu, Guannan Meng, Bing Huang, Xiaoya Zhou, Stavros Stavrakis, Menglong Wang, Xuefei Li, Liping Zhou, Yuhong Wang, Meng Wang, Zhenya Wang, Jielin Deng, Sunny S Po, Hong Jiang
BACKGROUND: Emerging evidence indicates gut microbes and their products could activate the autonomic nervous system (ANS), which plays important roles in the initiation and maintenance of atrial fibrillation (AF). Trimethylamine N-oxide (TMAO), a metabolite derived from gut microbes, is associated with cardiovascular diseases. The present study aimed to investigate the role of TMAO in the progression of AF. METHODS: In part 1: TMAO or saline was locally injected into 4 major atrial ganglionated plexi (GP) to clarify its effect on cardiac ANS and AF inducibility in normal canines...
March 15, 2018: International Journal of Cardiology
Floris Vanommeslaeghe, Wim Van Biesen, Manuel Dierick, Matthieu Boone, Annemieke Dhondt, Sunny Eloot
A novel technique based on micro-CT scanning is developed to quantify coagulation in fibers of hemodialyzers. This objectivation is needed to allow accurate assessment of thrombogenicity of dialyzers used during hemodialysis, for example when comparing different strategies to avoid coagulation and/or fiber blocking. The protocol allowed imaging at a resolution of 25 µm, making it possible to count the open, non-coagulated fibers in a non-invasive way. In 3 fresh, non-used FX600 hemodialyzers, patent fiber counts were extremely consistent (10748 ± 2)...
February 8, 2018: Scientific Reports
Benjamin Y Q Tan, Nicholas J H Ngiam, Sibi Sunny, Wan Yee Kong, Howen Tam, Tiong Beng Sim, Benjamin S H Leong, Chandra Bhartendu, Prakash R Paliwal, Raymond C S Seet, Bernard P L Chan, Hock Luen Teoh, Vijay K Sharma, Leonard L L Yeo
BACKGROUND: In acute ischemic stroke (AIS), treatment with intravenous tissue-type plasminogen activator (IV-tPA) is time-sensitive. All stroke centers make continual efforts to reduce door-to-needle time (DNT) with varying success. We present the impact of modifications to our stroke activation protocol on DNT. METHODS: We included 404 consecutive patients with AIS receiving IV-tPA between January 2014 and December 2016. First changes in stroke activation protocol were made in March 2015 in the form of prenotification by paramedics, direct transfer from ambulance to computed tomography (CT) scanner, and rapid en route neurological assessment by an emergency physician and neurologist...
February 5, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Marcos Pereira-Santos, José Yure Gomes Dos Santos, Gisele Queiroz Carvalho, Djanilson Barbosa Dos Santos, Ana Marlúcia Oliveira
Studies conducted among populations of tropical countries have reported high prevalences of vitamin D deficiency and insufficiency. Information resulting from meta-analyses on the spatial distribution of vitamin D deficiency and insufficiency in tropical countries is still rare. The aim of this review was investigated the prevalence of vitamin D deficiency and insufficiency among the Brazilian population. Observational studies were searched in eight electronically databases. Additionally, theses and dissertations and abstracts were screened...
February 8, 2018: Critical Reviews in Food Science and Nutrition
Ishan Lakhani, Mengqi Gong, Wing Tak Wong, George Bazoukis, Konstantinos Lampropoulos, Sunny Hei Wong, William K K Wu, Martin C S Wong, Kwok-Leung Ong, Tong Liu, Gary Tse
BACKGROUND: Fibroblast growth factor 21 is a signalling protein involved in cell differentiation, morphogenesis, proliferation and metabolism. Recent studies have associated increased levels of FGF21 in the development of cardiovascular diseases, whereas others have reported no significant associations. Therefore, this systematic review and meta-analysis evaluated the its value in predicting the risk of cardio-metabolic disorders and mortality. METHODS: PubMed and EMBASE were searched until 5th September 2017 for studies that evaluated the roles of FGF21 levels in cardio-metabolic disorders...
February 1, 2018: Metabolism: Clinical and Experimental
M Mojtabaee, F Ghorbani, M Mohsenzadeh, F S Beigee
INTRODUCTION: After significant improvement of the family consent rate to organ donation (OD) in recent years, owing to an increase in cultural activities and social awareness, a plateau has been reached. This study was performed to detect the causes for this plateau. METHODS: We reviewed exact causes of family refusal after providing a list of failed potential donors from July 2015 to December 2016. The expert coordinators responsible for handling the failed cases chose the cause of refusal from the previously prepared list...
January 2018: Transplantation Proceedings
Patrick Anselme
Terrestrial isopods (or woodlice), like the members of the other arthropod taxa, have a sophisticated nervous system that makes them sensitive to specific environmental factors. They can search for survival-related opportunities (e.g., approaching food sources or avoiding sunny areas). Two experiments examined how rotational stress could influence the propensity of common woodlice, Porcellio scaber to exhibit survival-related behaviors such as traveling and rearing up in a hostile environment. Experiment 1 assessed the behaviors of stressed and nonstressed woodlice exposed to a familiar or a novel environment without rewards...
February 5, 2018: Learning & Behavior
Yasser Madani, Anita Saigal, Juno Sunny, Leila Morris, Robin H Johns
OBJECTIVES: Chronic obstructive pulmonary disease (COPD) exacerbation is one of the most common reasons for hospital admission. Patients with COPD with a long length of stay (LoS) occupy a disproportionately high fraction of hospital bed-days. The objective of this study was to identify associations of long LoS in patients admitted with COPD exacerbation. MATERIAL AND METHODS: From December 2012 until June 2013, 499 patients were admitted to Queens Hospital, Romford, UK, with COPD exacerbation...
October 2017: Turkish Thoracic Journal
Saumya Sara Sunny, Julie Hephzibah, David Mathew, Joseph Dian Bondu, Nylla Shanthly, Regi Oommen
Serum thyroglobulin (Tg) and thyroid whole-body radioiodine scintigraphy (TWBS) are used in the follow-up of patients with papillary thyroid carcinoma (PTC) after total thyroidectomy. Symptoms of hypothyroidism are frequent as patients discontinue levothyroxine 1 month before visit, favoring the use of unstimulated serum Tg (uSTg) only. This study was done to determine the reliability of stimulated serum Tg levels (sSTg) over uSTg. A total of 650 patients with PTC came for follow-up between June 2011 and 2016...
January 2018: World Journal of Nuclear Medicine
Kathryn King-Shier, Alyssa Lau, Sunny Fung, Pamela LeBlanc, Simran Johal
AIMS: We aimed to develop an understanding of south Asian and Chinese people's preferences about where to find health information and how best to receive health information, relative to their white counterparts. BACKGROUND: South Asian and Chinese ethnic groups represent the largest proportion of Canada's growing visible minorities. There may be challenges to ensuring that south Asian and Chinese people have access to health information in the same way that others do...
February 3, 2018: Journal of Clinical Nursing
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