keyword
https://read.qxmd.com/read/32574894/repurposing-0-5-povidone-iodine-solution-in-otorhinolaryngology-practice-in-covid-19-pandemic
#21
JOURNAL ARTICLE
Mubarak Muhamed Khan, Sapna Ramkrishna Parab, Mandar Paranjape
UNLABELLED: SARS CoV 2 is very much homologous in structure to SARS CoV. Review of literature suggests the in-vitro virucidal action of povidone iodine in SARS CoV and MERS. The oropharynx and nasopharynx are target sites of SARS CoV 2. A significant proportion of COVID 19 sufferers are asymptomatic, but shedding these viral particles, PVP-I has been shown to be a safe therapy when used as a mouthwash or taken nasally or used during ophthalmic surgeries. AIMS: MATERIALS AND METHODS: 0...
2020: American Journal of Otolaryngology
https://read.qxmd.com/read/32520599/povidone-iodine-use-in-sinonasal-and-oral-cavities-a-review-of-safety-in-the-covid-19-era
#22
REVIEW
Samantha Frank, Joseph Capriotti, Seth M Brown, Belachew Tessema
OBJECTIVES: Approaches to nasal and oral decontamination with povidone-iodine (PVP-I) have been published to reduce nosocomial spread of Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2). The safety of PVP-I topically applied to the nasal and oral cavity is addressed by a literature review. The specific efficacy of PVP-I against coronaviruses and its potential efficacy against SARS-CoV-2 is discussed. METHODS: A review was performed utilizing PubMed and Cochrane Databases...
November 2020: Ear, Nose, & Throat Journal
https://read.qxmd.com/read/31663922/contact-sensitization-in-patients-with-chronic-leg-ulcers-results-of-a-5-year-retrospective-analysis
#23
JOURNAL ARTICLE
Tadas Raudonis, Rasa Aurelija Vankeviciute, Andre Lideikaite, Anna Greta Grigaityte, Jurate Grigaitiene
OBJECTIVES: To determine the frequency of contact sensitization among patients with chronic leg ulcers; to identify the most common allergens; and to examine possible relationships to ulcer duration, itching, exudate, and leg eczema. METHODS: Researchers conducted a 5-year retrospective analysis of 145 patients diagnosed with chronic leg ulcers who underwent skin patch testing with S-1000, LU-1000, and the commonly used dressing and antiseptic series. RESULTS: Investigators included 88 females (60...
December 2019: Advances in Skin & Wound Care
https://read.qxmd.com/read/31609802/outcomes-of-an-intraoperative-povidone-iodine-irrigation-protocol-in-spinal-surgery-for-surgical-site-infection-prevention
#24
JOURNAL ARTICLE
Yuki Onishi, Kazuhiro Masuda, Keiichiro Tozawa, Tatsuro Karita
STUDY DESIGN: This was a retrospective observational study. OBJECTIVE: The aim of this study was to evaluate the efficacy of our new protocol for preventing postoperative surgical site infection (SSI) following spinal surgery. SUMMARY OF BACKGROUND DATA: SSI following spinal surgery is a serious postoperative complication. Several studies have recently assessed the effectiveness of wound irrigation with povidone-iodine (PVP-I) for SSI prevention, but no consensus has been reached as to how PVP-I should be used in clinical practice...
December 2019: Clinical Spine Surgery
https://read.qxmd.com/read/31470798/comparison-of-disinfection-effect-between-benzalkonium-chloride-and-povidone-iodine-in-nasotracheal-intubation-a-randomized-trial
#25
JOURNAL ARTICLE
Aiji Sato-Boku, Keiji Nagano, Yoshiaki Hasegawa, Yuji Kamimura, Yoshiki Sento, MinHye So, Eisuke Kako, Masahiro Okuda, Naoko Tachi, Hidekazu Ito, Yushi Adachi, Kazuya Sobue
BACKGROUND: Nasotracheal intubation can potentially result in microbial contamination from the upper respiratory tract to the lower respiratory tracts. However, an ideal nasotracheal disinfection method is yet to be determined. Therefore, we compared the disinfection effects between benzalkonium chloride and povidone iodine in nasotracheal intubation. METHODS: Overall, this study enrolled 53 patients aged 20-70 years who were classified into classes 1 and 2 as per American Society of Anesthesiologists-physical status and were scheduled to undergo general anesthesia with NTI...
August 31, 2019: BMC Anesthesiology
https://read.qxmd.com/read/31066988/effect-of-local-polyhexanide-application-in-preventing-exit-site-infection-and-peritonitis-a-randomized-controlled-trial
#26
JOURNAL ARTICLE
Mevlut Ceri, Seref Rahmi Yilmaz, Selman Unverdi, Ilhan Kurultak, Murat Duranay
Topical antibiotic and antiseptic agents have been documented to reduce exit-site infection (ESI) and peritonitis in PD. The aim of this randomized controlled study was to evaluate the efficacy of polyhexanide in the prevention of ESI and peritonitis. Patients were excluded if they had active infection, > 18 years of age, ESI and peritonitis within the previous 4 weeks, received PD for less than 3-months and history of allergy to either drug. All patients were followed up until catheter removal, death, switch to dialysis, transplantation or the end of the study...
May 8, 2019: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/30916009/anaesthetic-management-of-patients-with-pre-existing-allergic-conditions-a-narrative-review
#27
REVIEW
Pascale Dewachter, Peter Kopac, Jose Julio Laguna, Paul Michel Mertes, Vito Sabato, Gerald W Volcheck, Peter J Cooke
This narrative review seeks to distinguish the clinical patterns of pre-existing allergic conditions from other confounding non-allergic clinical entities, and to identify the potential related risks and facilitate their perioperative management. Follow-up investigation should be performed after a perioperative immediate hypersensitivity to establish a diagnosis and provide advice for subsequent anaesthetics, the main risk factor for perioperative immunoglobulin E (IgE)-mediated anaphylaxis being a previous uninvestigated perioperative immediate hypersensitivity reaction...
July 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/28969846/prospective-single-center-observational-study-of-the-allergenic-potential-of-mercromina-film-and-other-common-antiseptics-in-patients-with-contact-dermatitis
#28
JOURNAL ARTICLE
S Baltà Cruz, N Moreno Ribera, M T Estrach Panella
INTRODUCTION: Although Mercromina Film and other topical antiseptics are widely used, they are not included in the standard series recommended by the Spanish Contact Dermatitis and Skin Allergy Research Group for testing suspected allergic contact dermatitis (ACD). Furthermore, no recent studies have investigated the allergenic potential of merbromin. OBJECTIVE: To determine the allergenic potential of merbromin and compare it with that of other topical antiseptics widely used in clinical practice, including povidone-iodine, chlorhexidine, and eosin...
January 2018: Actas Dermo-sifiliográficas
https://read.qxmd.com/read/27755287/biofilm-formation-on-bandage-contact-lenses-worn-by-patients-with-the-boston-type-1-keratoprosthesis-a-pilot-comparison-study-of-prophylactic-topical-vancomycin-15-mg-ml-and-linezolid-0-2
#29
JOURNAL ARTICLE
Asim V Farooq, Joshua H Hou, Sarmad Jassim, Zeeshan Haq, Elmer Y Tu, Jose de la Cruz, Maria S Cortina
OBJECTIVES: To determine the rate of biofilm formation on bandage contact lenses worn by patients with the Boston type 1 keratoprosthesis (K-Pro) while on prophylactic topical vancomycin versus linezolid. METHODS: Patients wearing a bandage contact lens (BCL) with a K-Pro were eligible for enrollment. After irrigation of the ocular surface with 5% povidone-iodine solution, each patient was placed on either topical vancomycin 15 mg/mL or linezolid 0.2% BID for one month...
September 2018: Eye & Contact Lens
https://read.qxmd.com/read/27601148/-iodine-allergy-a-medical-myth-with-risks-for-the-ophthalmological-patient
#30
REVIEW
T U Krohne, J-P Allam, N Novak, F G Holz
BACKGROUND: Preoperative disinfection with povidone-iodine results in a significant reduction of the risk for postoperative endophthalmitis and secondary irreversible vision loss in intraocular surgeries and intravitreal injections. Nevertheless, this important measure is often omitted if so-called "iodine allergy" is suspected. We analyze the physiological and allergological basis for the construct of "iodine allergy". METHODS: This article is based on a selective literature review using the search term "allergy" in combination with "iodine", "povidone", "indocyanine green", or "seafood"...
December 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://read.qxmd.com/read/27448925/endophthalmitis-after-intravitreal-injections-in-patients-with-self-reported-iodine-allergy
#31
JOURNAL ARTICLE
Bobeck S Modjtahedi, Tavé van Zyl, Hemang K Pandya, Robert E Leonard, Dean Eliott
PURPOSE: To present cases of endophthalmitis following intravitreal injections where povidone-iodine (PI) was not used as part of the surgical preparation. DESIGN: Retrospective case series. METHODS: All cases of presumed injection-related endophthalmitis presenting to the Massachusetts Eye and Ear Infirmary between June 2008 and November 2014 and Dean McGee Eye Institute between January 2010 and January 2015 were identified. Patients who did not receive PI preparation owing to documented self-reported allergy to iodine, iodine-containing contrast material, or shellfish were identified and their injection histories and clinical courses reviewed...
October 2016: American Journal of Ophthalmology
https://read.qxmd.com/read/26436913/povidone-iodine-rectal-preparation-at-time-of-prostate-needle-biopsy-is-a-simple-and-reproducible-means-to-reduce-risk-of-procedural-infection
#32
JOURNAL ARTICLE
Jay D Raman, Kathleen K Lehman, Kalyan Dewan, Girish Kirimanjeswara
Single institution and population-based studies highlight that infectious complications following transrectal ultrasound guided prostate needle biopsy (TRUS PNB) are increasing. Such infections are largely attributable to quinolone resistant microorganisms which colonize the rectal vault and are translocated into the bloodstream during the biopsy procedure. A povidone iodine rectal preparation (PIRP) at time of biopsy is a simple, reproducible method to reduce rectal microorganism colony counts and therefore resultant infections following TRUS PNB...
September 21, 2015: Journal of Visualized Experiments: JoVE
https://read.qxmd.com/read/26387623/-allergy-to-iodinated-drugs-and-to-foods-rich-in-iodine-iodine-is-not-the-allergenic-determinant
#33
REVIEW
Pascale Dewachter, Claudie Mouton-Faivre
"Iodine allergy" does not exist. The concept of "iodine allergy" should be abandoned since it may result in inappropriate measures such as drug, food or environmental eviction. Immediate or non-immediate allergic hypersensitivity to iodinated contrast media is not infrequent. The corresponding allergens have not been identified. Iodine is not involved. Immediate or non-immediate allergic hypersensitivity to povidone iodine is rare. The corresponding allergen is povidone in case of immediate hypersensitivity while nonoxynol might be involved during non-immediate hypersensitivity...
November 2015: La Presse Médicale
https://read.qxmd.com/read/25053635/an-unusual-complication-of-late-onset-allergic-contact-dermatitis-to-povidone-iodine-in-oral-maxillofacial-surgery-a-report-of-2-cases
#34
JOURNAL ARTICLE
M A Reyazulla, A L Gopinath, N Vaibhav, R P Raut
BACKGROUND: Povidone iodine (PVP-I) is a chemical complex of polyvinylpyrrolidone (also known as povidone or PVP) and elemental iodine. Iodine containing compounds are widely and commonly used as antiseptics and disinfectants. They are available in various forms like aqueous solution, tincture, aerosol, ointment, or foam. Skin irritation to them is due to the oxidative effects of iodine. Because of the low free iodine concentration in povidone-iodine, skin irritation is less frequent from short contact (1)...
July 2014: European Annals of Allergy and Clinical Immunology
https://read.qxmd.com/read/24497599/exit-site-infection-of-peritoneal-catheter-is-reduced-by-the-use-of-polyhexanide-results-of-a-prospective-randomized-trial
#35
RANDOMIZED CONTROLLED TRIAL
M Núñez-Moral, E Sánchez-Álvarez, I González-Díaz, B Peláez-Requejo, A Fernández-Viña, A Quintana-Fernández, C Rodríguez-Suárez
BACKGROUND: One of the most common and severe complications affecting peritoneal dialysis (PD) patients is exit-site infection of the peritoneal catheter; it is therefore of vital importance to prevent it. This complication has a negative impact on the success of the technique. In spite of this, there are no clear guidelines concerning how to take care of the exit site. The objective of this study was to assess the efficacy of polyhexanide in preventing exit-site infection over a 12-month period...
May 2014: Peritoneal Dialysis International
https://read.qxmd.com/read/24492204/a-comparison-of-the-irritant-and-allergenic-properties-of-antiseptics
#36
REVIEW
Jean-Marie Lachapelle
Over recent years, interest in the use of antiseptics has been reinforced as these molecules are not concerned by the problem of bacterial resistance. Whereas the in vitro efficacy of antiseptics has been well-studied, much less is known regarding their irritant and allergenic properties. This review provides an update on the comparative irritant and allergenic properties of commonly-used antiseptics in medicine nowadays. All antiseptics have irritant properties, especially when they are misused. Povidone-iodine has an excellent profile in terms of allergenicity...
January 2014: European Journal of Dermatology: EJD
https://read.qxmd.com/read/24312996/effects-of-food-colouring-added-to-2-chlorhexidine-gluconate-and-70-alcohol-for-surgical-site-antisepsis
#37
JOURNAL ARTICLE
Jason Chow, Jonathan Ng, Alvin Pun
Preoperative cleansing of a patient's skin with chlorhexidine gluconate (CHG) in alcohol is superior to cleansing with povidone-iodine for preventing surgical site infection (SSI) after clean-contaminated surgery (Darouilche et al 2010). However, 2% CHG in 70% alcohol, tinted pink, is colourless when applied to limbs for surgery and complete coverage cannot be assured. The purpose of the study was to evaluate the efficacy of food colouring added to CHG in preoperative skin preparation. Two hundred and eight subjects were randomly selected from a population of healthy young adults and were given a questionnaire...
November 2013: Journal of Perioperative Practice
https://read.qxmd.com/read/24280923/preoperative-antiseptic-skin-preparations-and-reducing-ssi
#38
JOURNAL ARTICLE
Mohammed Abdullah Al Maqbali
Surgical site infection (SSI) can affect the quality of care and increase the morbidity and mortality rate in after-surgical procedure. The use of an antiseptic skin preparation agent before the procedure can reduce the pathogens in the skin surface around the incision. Indicating the type of skin antiseptic preparation could prevent the infection and contamination of the wound. The most commonly used types of skin preparations are chlorhexidine and povidone iodine. However, the antiseptic solutions of both agents are strengthened with alcohol to prevent postoperative wound infection...
November 28, 2013: British Journal of Nursing: BJN
https://read.qxmd.com/read/23963423/committee-opinion-no-571-solutions-for-surgical-preparation-of-the-vagina
#39
JOURNAL ARTICLE
(no author information available yet)
Currently, only povidone-iodine preparations are approved for vaginal surgical-site antisepsis. However, there are compelling reasons to consider chlorhexidine gluconate solutions for off-label use in surgical preparation of the vagina, especially in women with allergies to iodine. Although chlorhexidine gluconate solutions with high concentrations of alcohol are contraindicated for surgical preparation of the vagina, solutions with low concentrations of alcohol (eg, 4%) are both safe and effective for off-label use as vaginal surgical preparations and may be used as an alternative to iodine-based preparations in cases of allergy or when preferred by the surgeon...
September 2013: Obstetrics and Gynecology
https://read.qxmd.com/read/22877600/symptomatic-trichomonas-vaginalis-infection-in-the-setting-of-severe-nitroimidazole-allergy-successful-treatment-with-boric-acid
#40
JOURNAL ARTICLE
Christina Muzny, Arti Barnes, Leandro Mena
This report describes a patient with symptomatic Trichomonas vaginalis infection who was unable to tolerate nitroimidazole drugs because of severe hypersensitivity, for which desensitisation was not possible. Use of intravaginal clotrimazole, intravaginal paromomycin, intravaginal furazolidone, povidone-iodine douches, and oral nitazoxanide were unsuccessful in eradicating the patient's T. vaginalis infection. A 2-month course of intravaginal topical boric acid subsequently achieved a complete symptomatic cure and the patient remained T...
September 2012: Sexual Health
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