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anorexia nervosa treatment

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https://www.readbyqxmd.com/read/28334444/the-partial-dopamine-d2-receptor-agonist-aripiprazole-is-associated-with-weight-gain-in-adolescent-anorexia-nervosa
#1
Guido K W Frank, Megan E Shott, Jennifer O Hagman, Marissa A Schiel, Marisa C DeGuzman, Brogan Rossi
OBJECTIVE: Finding medication to support treatment of anorexia nervosa has been difficult. Neuroscience-based approaches may help in this effort. Recent brain imaging studies in adults and adolescents with anorexia nervosa suggest that dopamine-related reward circuits are hypersensitive and could provide a treatment target. METHODS: Here, we present a retrospective chart review of 106 adolescents with anorexia nervosa some of whom were treated with the dopamine D2 receptor partial agonist aripiprazole during treatment in a specialized eating disorder program...
March 23, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28331571/clinical-evaluation-of-autistic-symptoms-in-women-with-anorexia-nervosa
#2
Heather Westwood, William Mandy, Kate Tchanturia
BACKGROUND: Despite a suggested link between anorexia nervosa (AN) and autism spectrum disorder (ASD), previous studies have used self-report or diagnostic criteria to assess for ASD in AN populations, rather than direct observation of symptom characteristic of ASD. The aim of this study was to use a standardised, clinical assessment of ASD, the Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2), to investigate the presence of autistic symptoms in a cross-sectional sample of women with AN...
2017: Molecular Autism
https://www.readbyqxmd.com/read/28324677/intermittent-explosive-disorder-and-eating-disorders-analysis-of-national-comorbidity-and-research-samples
#3
Karen M Jennings, Jennifer E Wildes, Emil F Coccaro
OBJECTIVE: Clinical studies suggest comorbidity between eating disorders and aggressive behaviors. This study examined the pattern of comorbidity between intermittent explosive disorder (IED) and eating disorders (ED). METHODS: Data were analyzed from both the adult and adolescent samples of the National Comorbidity Survey-Replication (n = 19,430) and a clinical research sample (n = 1,642). RESULTS: Lifetime prevalence of Any ED was elevated in IED vs...
March 2, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28323350/characteristics-of-seeking-treatment-among-u-s-adolescents-with-eating-disorders
#4
Lauren N Forrest, April R Smith, Sonja A Swanson
OBJECTIVE: The majority of persons with eating disorders (EDs) do not seek ED treatment, yet little is known about treatment-seeking barriers or facilitators. The aim of the study is to describe the characteristics associated with seeking ED treatment among U.S. adolescents with EDs. METHOD: Data from a nationally representative cross-sectional study of U.S. adolescents ages 13-18 years were used for these analyses. Specifically, adolescents who met criteria for lifetime EDs (N = 281) were included...
March 21, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28319785/the-long-and-complex-road-in-the-search-for-treatment-for-mental-disorders-an-analysis-of-the-process-in-five-groups-of-patients
#5
Gema Del Valle, Amparo Belloch, Carmen Carrió
Seeking treatment for mental-health problems is a complex process, with different underlying motives in each stage. However, the entire process and these motives have hardly been investigated. This study aims to analyze the different stages of the help-seeking process and their underlying motives in five groups of patients with different mental disorders. In all, 156 patients seeking treatment in outpatient mental health clinics were individually interviewed: 71 had Obsessive-Compulsive Disorder (OCD), 21 had Agoraphobia (AGO), 18 had Major Depressive Disorder (MDD), 20 had Anorexia Nervosa (AN), and 22 had Cocaine Dependence (COC)...
March 15, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28318287/findings-from-a-couple-based-open-trial-for-adult-anorexia-nervosa
#6
Donald H Baucom, Jennifer S Kirby, Melanie S Fischer, Brian R Baucom, Robert Hamer, Cynthia M Bulik
Adult anorexia nervosa (AN) often is persistent, significantly erodes quality of life for both the patient and loved ones, and carries high medical and psychiatric comorbidity. Whereas individual psychotherapy for adult AN leads to improvement in some patients, recent findings indicate that the magnitude of improvement is limited: Only a small percentage of individuals fully recover and dropout rates are high. Thus, it is important to build upon current interventions to improve treatment response. We present results from an open trial of a couple-based intervention for adult anorexia nervosa as an adjunct treatment to standard multidisciplinary care...
March 20, 2017: Journal of Family Psychology: JFP
https://www.readbyqxmd.com/read/28301566/eating-symptomatology-and-general-psychopathology-in-patients-with-anorexia-nervosa-from-china-uk-and-spain-a-cross-cultural-study-examining-the-role-of-social-attitudes
#7
Zaida Agüera, Nicola Brewin, Jue Chen, Roser Granero, Qing Kang, Fernando Fernandez-Aranda, Jon Arcelus
Cultural studies exploring differences in the manifestation of anorexia nervosa (AN) have primarily focus on Western and non-Western cultures. However, no study so far has considered the role that social attitudes (i.e. Collectivist vs. Individualist cultural values) have in the clinical manifestations of eating disorders, including AN patients. With this in mind, the aim of this study is to compare eating and general psychopathology in a large sample of individuals diagnosed with AN from China, Spain, and United Kingdom (UK), in order to study the differences according to belonging to Western or non-Western country, or the country's Individualist Index (IDV)...
2017: PloS One
https://www.readbyqxmd.com/read/28298897/plasma-ghrelin-levels-are-associated-with-anorexia-but-not-cachexia-in-patients-with-nsclc
#8
Susanne Blauwhoff-Buskermolen, Jacqueline A E Langius, Annemieke C Heijboer, Annemarie Becker, Marian A E de van der Schueren, Henk M W Verheul
Background and Aims: The ghrelin receptor is one of the new therapeutic targets in the cancer anorexia-cachexia syndrome. Previous studies revealed that plasma ghrelin levels were high in patients with anorexia nervosa and low in obese subjects. We studied to what extent ghrelin levels are related with anorexia and cachexia in patients with cancer. Materials and Methods: Fasted ghrelin levels were determined as well as anorexia and cachexia in patients with stage III/IV non-small cell lung cancer before chemotherapy...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28298497/anorexia-nervosa-and-bone-densitometry
#9
Havilah Adkins
Anorexia nervosa is a psychological disorder with extensive physical complications that require care and monitoring from a diverse team of health care professionals. Although it can affect people of various ages and both sexes, anorexia most frequently occurs in adolescent girls during a crucial period of skeletal development. This article presents an overview of anorexia nervosa, followed by focused discussions of its effects on bone development, treatment of bone loss, and the radiologic technologist's role in caring for anorexic patients...
March 2017: Radiologic Technology
https://www.readbyqxmd.com/read/28291261/modeling-anorexia-nervosa-transcriptional-insights-from-human-ipsc-derived-neurons
#10
P D Negraes, F R Cugola, R H Herai, C A Trujillo, A S Cristino, T Chailangkarn, A R Muotri, V Duvvuri
Anorexia nervosa (AN) is a complex and multifactorial disorder occurring predominantly in women. Despite having the highest mortality among psychiatric conditions, it still lacks robust and effective treatment. Disorders such as AN are most likely syndromes with multiple genetic contributions, however, genome-wide studies have been underpowered to reveal associations with this uncommon illness. Here, we generated induced pluripotent stem cells (iPSCs) from adolescent females with AN and unaffected controls...
March 14, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28288802/non-invasive-brain-stimulation-for-food-cravings-consumption-and-disorders-of-eating-a-review-of-methods-findings-and-controversies
#11
REVIEW
Peter A Hall, Corita Vincent
OBJECTIVE: To describe the state of the human research literature pertaining to the use of non-invasive brain stimulation (NIBS) procedures for modulating food cravings, food consumption, and treating disorders of eating (i.e., obesity, bulimia nervosa, and anorexia nervosa). METHODS: A narrative review of methods, empirical findings, and current areas of controversy. Both single-session experimental and multi-session therapeutic modalities are considered, separately for repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) technologies...
March 10, 2017: Appetite
https://www.readbyqxmd.com/read/28284563/history-of-overweight-obesity-as-predictor-of-care-received-at-1-year-follow-up-in-adolescents-with-anorexia-nervosa-or-atypical-anorexia-nervosa
#12
Grace A Kennedy, Sara F Forman, Elizabeth R Woods, Albert C Hergenroeder, Kathleen A Mammel, Martin M Fisher, Rollyn M Ornstein, S Todd Callahan, Neville H Golden, Cynthia J Kapphahn, Andrea K Garber, Ellen S Rome, Tracy K Richmond
PURPOSE: Previous research has indicated that patients with anorexia nervosa (AN) or atypical AN with premorbid history of overweight/obesity have greater weight loss and longer illness duration than patients with no such history. However, little is known about the association of premorbid overweight/obesity and receiving inpatient medical care during treatment for an eating disorder. METHODS: Using logistic regression, we sought to determine if history of overweight/obesity was associated with receiving inpatient medical care in a sample of 522 patients (mean age 15...
March 8, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28271454/depression-worry-and-psychosocial-functioning-predict-eating-disorder-treatment-outcomes-in-a-residential-and-partial-hospitalization-setting
#13
Laura K Fewell, Cheri A Levinson, Lynn Stark
This retrospective study explores depression, worry, psychosocial functioning, and change in body mass index (BMI) as predictors of eating disorder (ED) symptomatology and BMI at discharge and 1-year follow-up from a residential and partial hospitalization ED treatment center. Participants were 423 male and female patients receiving treatment at an ED treatment center. Results indicate significant improvement in ED symptomatology, psychological impairment, and change in BMI (in patients with anorexia nervosa) at treatment discharge and follow-up compared to treatment admission (ps < 0...
March 7, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/28265411/outcomes-of-an-inpatient-medical-nutritional-rehabilitation-protocol-in-children-and-adolescents-with-eating-disorders
#14
Rebecka Peebles, Andrew Lesser, Courtney Cheek Park, Kerri Heckert, C Alix Timko, Eleni Lantzouni, Ronald Liebman, Laurel Weaver
BACKGROUND: Medical stabilization through inpatient nutritional rehabilitation is often necessary for patients with eating disorders (EDs) but includes the inherent risk of refeeding syndrome. Here we describe our experience of implementing and sustaining an inpatient nutritional rehabilitation protocol designed to strategically prepare patients with EDs and their families for discharge to a home setting in an efficient and effective manner from a general adolescent medicine unit. We report outcomes at admission, discharge, and 4-weeks follow-up...
2017: Journal of Eating Disorders
https://www.readbyqxmd.com/read/28265410/adolescents-with-full-or-subthreshold-anorexia-nervosa-in-a-naturalistic-sample-characteristics-and-treatment-outcome
#15
Katarina Lindstedt, Lars Kjellin, Sanna Aila Gustafsson
BACKGROUND: Anorexia Nervosa (AN) destroys developmentally important early years of many young people and knowledge is insufficient regarding course, treatment outcome and prognosis. Only a few naturalistic studies have been conducted within the field of eating disorder (ED) research. In this naturalistic study we included adolescents with AN or subthreshold AN treated in outpatient care, and the overall aim was to examine sample characteristics and treatment outcome. Additional aims were to examine potential factors associated with remission as an outcome variable, and possible differences between three time periods for treatment onset...
2017: Journal of Eating Disorders
https://www.readbyqxmd.com/read/28263397/menstrual-cycle-loss-and-resumption-among-patients-with-anorexia-nervosa-spectrum-eating-disorders-is-relative-or-absolute-weight-more-influential
#16
Laura A Berner, Emily H Feig, Ashley A Witt, Michael R Lowe
OBJECTIVE: Prior research suggests that both body mass index (BMI) and weight suppression (highest past weight minus current weight; WS) are important in determining adult anorexia nervosa (AN) severity. We examined associations between amenorrhea and WS, DSM-5 BMI severity category, and highest premorbid BMI among patients with AN. METHOD: Participants (N = 69) were adult female AN-spectrum patients at two residential treatment facilities. At admission, height, and weight were measured, and participants completed questionnaires assessing menstrual status and weight history...
March 6, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28261139/assessment-of-dysfunctional-cognitions-in-binge-eating-disorder-factor-structure-and-validity-of-the-mizes-anorectic-cognitions-questionnaire-revised-mac-r
#17
Isabelle Carrard, Stephane Rothen, Maaike Kruseman, Yasser Khazaal
Background: Dysfunctional cognitions regarding weight and shape and their implications for self-esteem are considered core features of anorexia nervosa and bulimia nervosa. However, they have also been associated with the severity of binge eating disorder (BED). Therefore, they should be screened with appropriate instruments to tailor treatment to individual patient needs. The Mizes Anorectic Cognitions-Revised (MAC-R) is a self-report questionnaire that lists dysfunctional cognitions related to three hypothesized core beliefs typical of the psychopathology of eating disorders: weight and eating as the basis of approval from others; the belief that rigid self-control is fundamental to self-worth; and the rigidity of weight- and eating-regulation efforts...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28259721/neuroendocrinology-and-brain-imaging-of-reward-in-eating-disorders-a-possible-key-to-the-treatment-of-anorexia-nervosa-and-bulimia-nervosa
#18
REVIEW
Alessio Maria Monteleone, Giovanni Castellini, Umberto Volpe, Valdo Ricca, Lorenzo Lelli, Palmiero Monteleone, Mario Maj
Anorexia nervosa and bulimia nervosa are severe eating disorders whose etiopathogenesis is still unknown. Clinical features suggest that eating disorders may develop as reward-dependent syndromes, since eating less food is perceived as rewarding in anorexia nervosa while consumption of large amounts of food during binge episodes in bulimia nervosa aims at reducing the patient's negative emotional states. Therefore, brain reward mechanisms have been a major focus of research in the attempt to contribute to the comprehension of the pathophysiology of these disorders...
March 1, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28244033/young-people-s-experience-of-individual-cognitive-remediation-therapy-crt-in-an-inpatient-eating-disorder-service-a-qualitative-study
#19
Lucia Giombini, Sophie Nesbitt, Lauren Waples, Emilia Finazzi, Abigail Easter, Kate Tchanturia
INTRODUCTION AND PURPOSE: Current literature shows promising results regarding the efficacy of Cognitive Remediation Therapy for Anorexia Nervosa (AN); however, there is a paucity of studies considering the use of CRT in Young People (YP). The aim of this study was to examine YP's experiences of individual CRT in an inpatient eating disorder unit. METHOD: Seventy letters following a cycle of eight individual CRT sessions were analysed using thematic analysis, adopting an inductive approach...
February 27, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/28241985/cardiogenic-shock-caused-by-a-left-midventricular-obstruction-during-refeeding-in-a-patient-with-anorexia-nervosa
#20
Yoko Sakamoto, Hidetaka Kioka, Ryota Hashimoto, Saori Takeda, Kota Momose, Tomohito Ohtani, Osamu Yamaguchi, Masafumi Wasa, Satoshi Nakatani, Yasushi Sakata
OBJECTIVE: Refeeding syndrome occurs when reinstating nutrition to severely malnourished patients. It can sometimes be fatal, particularly as a result of cardiac involvement such as congestive heart failure and arrhythmias. The aim of this study was to report a case of cardiogenic shock that occurred during refeeding in a patient with anorexia nervosa (AN). The cardiogenic shock was due to a previously unrecognized mechanism, namely a transient left midventricular obstruction that completely disappeared after treatment...
March 2017: Nutrition
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