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anorexia nervosa treatment

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https://www.readbyqxmd.com/read/27933021/dimensions-of-compulsive-exercise-across-eating-disorder-diagnostic-subtypes-and-the-validation-of-the-spanish-version-of-the-compulsive-exercise-test
#1
Sarah Sauchelli, Jon Arcelus, Roser Granero, Susana Jiménez-Murcia, Zaida Agüera, Amparo Del Pino-Gutiérrez, Fernando Fernández-Aranda
Objectives: Compulsive exercise in eating disorders has been traditionally considered as a behavior that serves the purpose of weight/shape control. More recently, it has been postulated that there may be other factors that drive the compulsive need to exercise. This has led to the development of the Compulsive Exercise Test (CET); a self-reported questionnaire that aims to explore the cognitive-behavioral underpinnings of compulsive exercise from a multi-faceted perspective. The objectives of this study were threefold: (1) to validate the Spanish version of the CET; (2) to compare eating disorder diagnostic subtypes and a healthy control group in terms of the factors that drive compulsive exercise as defined by the CET; (3) to explore how the dimensions evaluated in the CET are associated with eating disorder symptoms and general psychopathology...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27928853/early-response-to-treatment-in-eating-disorders-a-systematic-review-and-a-diagnostic-test-accuracy-meta-analysis
#2
REVIEW
Bruno Palazzo Nazar, Louise Kathrine Gregor, Gaia Albano, Angelo Marchica, Gianluca Lo Coco, Valentina Cardi, Janet Treasure
OBJECTIVE: Early response to eating disorders treatment is thought to predict a later favourable outcome. A systematic review of the literature and meta-analyses examined the robustness of this concept. METHOD: The criteria used across studies to define early response were summarised following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Diagnostic Test Accuracy methodology was used to estimate the size of the effect. RESULTS: Findings from 24 studies were synthesized and data from 14 studies were included in the meta-analysis...
December 7, 2016: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/27924450/neurobiochemical-and-psychological-factors-influencing-the-eating-behaviors-and-attitudes-in-anorexia-nervosa
#3
REVIEW
Teresa Grzelak, Agata Dutkiewicz, Elzbieta Paszynska, Monika Dmitrzak-Weglarz, Agnieszka Slopien, Marta Tyszkiewicz-Nwafor
The aim of this study was to determine the characteristic features which contribute to inappropriate eating attitudes in people suffering from anorexia nervosa, based on an analysis of recent data. Factors influencing these attitudes have a genetic, neurobiological, biochemical, affective-motivational, cognitive, and behavioral background. Another important issue addressed in the paper is a description of the mechanism leading to continuous dietary restrictions. The altered activity of neurotransmitters modulating patients' moods after the consumption of food and a disturbed responsiveness to enterohormones enhance affective-motivational and cognitive aspects which, in turn, impede the improvement of eating behaviors...
December 6, 2016: Journal of Physiology and Biochemistry
https://www.readbyqxmd.com/read/27923148/patient-and-clinician-reported-outcome-in-eating-disorders
#4
Laura Al-Dakhiel Winkler, Jacob Stampe Frølich, Claire Gudex, Kirsten Hørder, Niels Bilenberg, René Klinkby Støving
Patient-reported outcome is increasingly applied in health sciences. Patients with eating disorders (EDs) characteristically have a different opinion of their needs to that of the health professionals, which can lead to ambivalence towards treatment and immense compliance difficulties. This cross-sectional study compared data assessed by the clinician to patient-reported measures in patients with a history of EDs. We included data from a cohort of patients with EDs (n=544) referred to a specialized ED unit in Denmark...
November 30, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27909746/brain-glutamate-in-anorexia-nervosa-a-magnetic-resonance-spectroscopy-case-control-study-at-7-tesla
#5
Beata R Godlewska, Alexandra Pike, Ann L Sharpley, Agnes Ayton, Rebecca J Park, Philip J Cowen, Uzay E Emir
RATIONALE: Anorexia nervosa (AN) is a serious psychiatric disorder with high morbidity and mortality. There are no established pharmacological treatments and the neurobiology of the condition is poorly understood. Previous studies using magnetic resonance spectroscopy (MRS) have shown that AN may be associated with reductions in indices of brain glutamate; however, at conventional field strengths (≤3 T), it is difficult to separate glutamate from its precursor and metabolite, glutamine...
December 1, 2016: Psychopharmacology
https://www.readbyqxmd.com/read/27895913/listening-in-the-dark-why-we-need-stories-of-people-living-with-severe-and-enduring-anorexia-nervosa
#6
EDITORIAL
Janet Conti, Paul Rhodes, Heather Adams
A bold step forward in our approach to Severe and Enduring Anorexia Nervosa invites new paradigms for research and practice. It provides an opportunity for us to explore fault lines, both in our communities of practice and the social structures that inform them. This paper serves to question the medical metaphors on which treatment has been based, in favour of alternative perspectives that resonate more clearly with the lived experience of those for whom it has failed. We invite the consideration of alternative metaphors, which can disrupt the notion of heroic patients (and therapists), mediate against acts of self-silencing and sensitising us to more radical acts of listening...
2016: Journal of Eating Disorders
https://www.readbyqxmd.com/read/27891176/a-series-of-patients-with-purging-type-anorexia-nervosa-who-do-tube-vomiting
#7
Takeshi Horie, Saki Harashima, Ryo Yoneda, Maiko Hiraide, Shuji Inada, Makoto Otani, Kazuhiro Yoshiuchi
BACKGROUND: It is important for clinicians to assess their patients' purging behavior. Various methods of purging, such as self-induced vomiting are well-known. Because patients do not always report their purging behavior, knowing the clinical signs that indicate the behavior is useful. However, we have experienced patients who did not have the reported physical signs of self-induced vomiting because they used hoses instead of their fingers to purge their stomach contents, which they call "tube vomiting"...
2016: BioPsychoSocial Medicine
https://www.readbyqxmd.com/read/27889099/eating-disorders-in-the-context-of-preconception-care-fertility-specialists-knowledge-attitudes-and-clinical-practices
#8
Iolanda S Rodino, Susan M Byrne, Katherine A Sanders
OBJECTIVE(S): To gauge fertility specialists' knowledge, clinical practices, and training needs in regard to eating disorders. DESIGN: Cross-sectional study. SETTINGS: Fertility clinics. PARTICIPANTS: Eighty Australian and New Zealand fertility specialists who were members of the Fertility Society of Australia. INTERVENTION(S): None. MAIN OUTCOME MEASURES(S): Responses to an anonymously completed online questionnaire...
November 23, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27887708/pulsatile-gonadotropin-releasing-hormone-therapy-in-persistent-amenorrheic-weight-recovered-anorexia-nervosa-patients
#9
Natacha Germain, Anaïs Fauconnier, Jean-Philippe Klein, Amélie Wargny, Yadh Khalfallah, Chrysoula Papastathi-Boureau, Bruno Estour, Bogdan Galusca
OBJECTIVE: To compare hormonal and clinical responses to GnRH pulsatile treatment in weight-recovered anorexia nervosa patients (Rec-AN) with persistent functional hypothalamic amenorrhea (HA) vs. in patients with secondary and primary HA. DESIGN: Retrospective, observational, ambulatory study. SETTING: University hospital. PATIENT(S): Forty-one women: 19 Rec-AN (body mass index >18.5 kg/m(2) without menses recovery), 15 secondary HA without any eating disorders patients (SHA), and 7 primary HA patients (PHA)...
November 22, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27881106/a-pragmatic-randomised-multi-centre-trial-of-multifamily-and-single-family-therapy-for-adolescent-anorexia-nervosa
#10
Ivan Eisler, Mima Simic, John Hodsoll, Eia Asen, Mark Berelowitz, Frances Connan, Gladys Ellis, Pippa Hugo, Ulrike Schmidt, Janet Treasure, Irene Yi, Sabine Landau
BACKGROUND: Considerable progress has been made in recent years in developing effective treatments for child and adolescent anorexia nervosa, with a general consensus in the field that eating disorders focussed family therapy (often referred to as Maudsley Family Therapy or Family Based Treatment) currently offers the most promising outcomes. Nevertheless, a significant number do not respond well and additional treatment developments are needed to improve outcomes. Multifamily therapy is a promising treatment that has attracted considerable interest and we report the results of the first randomised controlled trial of multifamily therapy for adolescent anorexia nervosa...
November 24, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27869569/change-in-expressed-emotion-and-treatment-outcome-in-adolescent-anorexia-nervosa
#11
Ashley A Moskovich, C Alix Timko, Lisa K Honeycutt, Nancy L Zucker, Rhonda M Merwin
Expressed emotion (EE) has been associated with poor outcomes in anorexia nervosa (AN); however, whether changes in EE predict superior treatment outcomes is unknown. The current study examined whether decreases in EE during an open trial of a novel family-based treatment for AN predicted symptoms at end of treatment. Forty-seven adolescents (12-18 years of age) with AN or sub-threshold AN and their parents (mothers: n = 47, fathers: n = 39) participated in 6 months of family treatment. Measures of AN symptomatology (Eating Disorder Examination completed by adolescent and end of treatment recovery status) and parental EE (Family Questionnaire completed by parents which measures two facets of EE: critical communication [CC] and emotional over-involvement [EOI]) were collected at baseline and end of treatment...
November 21, 2016: Eating Disorders
https://www.readbyqxmd.com/read/27869566/gastrointestinal-comorbidities-which-complicate-the-treatment-of-anorexia-nervosa
#12
Margherita Mascolo, Bashir Geer, Joshua Feuerstein, Philip S Mehler
Patients with anorexia nervosa often voice a multitude of symptoms in regards to their gastrointestinal tract. These complaints can complicate the treatment of their eating disorder as they distract attention from the important goal of weight restoration. Moreover, the restricting of certain food groups also makes the task of weight restoration substantially more difficult, or may result in binging. Therefore a working knowledge of common gastrointestinal comorbidities, such as celiac disease, irritable bowel syndrome, inflammatory bowel disease, and gastroparesis, is useful when treating a patient who has anorexia nervosa...
November 21, 2016: Eating Disorders
https://www.readbyqxmd.com/read/27863331/intensive-enhanced-cognitive-behavioural-therapy-for-severe-and-enduring-anorexia-nervosa-a-longitudinal-outcome-study
#13
Simona Calugi, Marwan El Ghoch, Riccardo Dalle Grave
OBJECTIVE: This study aimed to evaluate short- and long-term outcomes in patients with severe and enduring anorexia nervosa (SE-AN), as compared with those with non SE-AN (NSE-AN), both treated via an inpatient programme based on a "recovery model" approach. METHODS: Sixty-six adult patients with anorexia nervosa (AN) were recruited from among consecutive referrals to a community-based eating disorder clinic offering inpatient enhanced cognitive behavioural therapy for eating disorders (CBT-E)...
November 12, 2016: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/27862127/the-impact-of-dsm-5-on-eating-disorder-diagnoses
#14
Megen Vo, Erin C Accurso, Andrea B Goldschmidt, Daniel Le Grange
OBJECTIVE: Eating disorder diagnostic criteria were revised from the fourth to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV and -5, respectively). This study examines the impact of these revisions on rates of eating disorder diagnoses in treatment-seeking youth. METHOD: Participants were 651 youth, ages 7-18 years, presenting to an outpatient eating disorders program who met criteria for a DSM-IV eating disorder diagnosis on intake...
November 12, 2016: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/27859581/the-risk-of-eating-disorders-comorbid-with-attention-deficit-hyperactivity-disorder-a-systematic-review-and-meta-analysis
#15
REVIEW
Bruno Palazzo Nazar, Camila Bernardes, Gemma Peachey, Joseph Sergeant, Paulo Mattos, Janet Treasure
OBJECTIVE: There has been interest in whether people with Attention-Deficit/Hyperactivity Disorder (ADHD) are at higher risk of developing an Eating Disorder (ED). The aim of this study was estimate the size of this association with a meta-analysis of studies. METHODS: We retrieved studies following PRISMA guidelines from a broad range of databases. RESULTS: Twelve studies fitted our primary aim in investigating ED in ADHD populations (ADHD = 4,013/Controls = 29,404), and five exploring ADHD in ED populations (ED = 1,044/Controls = 11,292)...
November 15, 2016: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/27852657/kwashiorkor-an-unexpected-complication-to-anorexia-nervosa
#16
Camilla Viola Buskbjerg Palm, Jacob Stampe Frølich, Lena Sønder Snogdal, René Klinkby Støving
We present the case of a woman aged 48 years, diagnosed with anorexia nervosa (AN) at the age of 12. She was admitted to a highly specialised eating disorder facility with distended abdomen, muscular atrophy, ulcerative dermatitis, electrolyte derangements and low serum albumin. Her weight was 53.1 kg, corresponding to a body mass index (BMI) of 17.9 kg/m(2) After initial stabilisation, a therapeutic ascites puncture relieved the patient from 6500 mL of ascites. After 6 weeks of nutritional and diuretic treatment, the patient was discharged with a weight of 46...
November 15, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27835724/a-systematic-review-of-bright-light-therapy-for-eating-disorders
#17
Marshall T Beauchamp, Jennifer D Lundgren
Objective: Bright light therapy is a noninvasive biological intervention for disorders with nonnormative circadian features. Eating disorders, particularly those with binge-eating and night-eating features, have documented nonnormative circadian eating and mood patterns, suggesting that bright light therapy may be an efficacious stand-alone or adjunctive intervention. The purpose of this systematic literature review, using PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, was (1) to evaluate the state of the empirical treatment outcome literature on bright light therapy for eating disorders and (2) to explore the timing of eating behavior, mood, and sleep-related symptom change so as to understand potential mechanisms of bright light therapy action in the context of eating disorder treatment...
October 27, 2016: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/27832747/cognitive-remediation-therapy-crt-as-a-treatment-enhancer-of-eating-disorders-and-obsessive-compulsive-disorders-study-protocol-for-a-randomized-controlled-trial
#18
Boris van Passel, Unna Danner, Alexandra Dingemans, Eric van Furth, Lot Sternheim, Annemarie van Elburg, Agnes van Minnen, Marcel van den Hout, Gert-Jan Hendriks, Daniëlle Cath
BACKGROUND: Anorexia nervosa (AN) and Obsessive Compulsive Disorder (OCD) are among the most incapacitating and costly of mental disorders. Cognitive Behaviour Therapy (CBT), medication, and combination regimens, to which in AN personalised guidance on weight control is added, are moderately successful, leaving room for more effective treatment algorithms. An underlying deficit which the two disorders share is cognitive inflexibility, a trait that is likely to impede treatment engagement and reduce patients' ability to benefit from treatment...
November 10, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27826742/the-change-process-in-adult-anorexia-nervosa-inpatient-treatment-a-path-model
#19
Antje Gumz, Denise Kästner, Angelika Weigel, Anne Daubmann, Bernhard Osen, Matislava Karacic, Eileen Wollburg, Ulrich Voderholzer, Bernd Löwe
PURPOSE: Knowledge on the change process in the treatment of anorexia nervosa (AN) is an important starting point for the improvement of treatment, yet very little evidence exists. In an exploratory analysis, we aimed to investigate the interdependencies between higher-rank change process factors, BMI and AN-specific cognitions and behaviours over the course of inpatient treatment. METHODS: We included 176 female adult AN inpatients from three specialized centres...
November 8, 2016: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/27826222/activity-based-anorexia-reduces-body-weight-without-inducing-a-separate-food-intake-microstructure-or-activity-phenotype-in-female-rats-mediation-via-an-activation-of-distinct-brain-nuclei
#20
Sophie Scharner, Philip Prinz, Miriam Goebel-Stengel, Peter Kobelt, Tobias Hofmann, Matthias Rose, Andreas Stengel
Anorexia nervosa (AN) is accompanied by severe somatic and psychosocial complications. However, the underlying pathogenesis is poorly understood, treatment is challenging and often hampered by high relapse. Therefore, more basic research is needed to better understand the disease. Since hyperactivity often plays a role in AN, we characterized an animal model to mimic AN using restricted feeding and hyperactivity. Female Sprague-Dawley rats were divided into four groups: no activity/ad libitum feeding (ad libitum, AL, n = 9), activity/ad libitum feeding (activity, AC, n = 9), no activity/restricted feeding (RF, n = 12) and activity/restricted feeding (activity-based anorexia, ABA, n = 11)...
2016: Frontiers in Neuroscience
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