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https://www.readbyqxmd.com/read/28412305/memantine-improves-outcomes-after-repetitive-traumatic-brain-injury
#1
Zhengrong Mei, Jianhua Qiu, Sasha Alcon, Jumana Hashim, Alexander Rotenberg, Yan Sun, William P Meehan, Rebekah Mannix
Repetitive mild traumatic brain injury (rmTBI; e.g., sports concussions) is common and results in significant cognitive impairment. Targeted therapies for rmTBI are lacking, though evidence from other injury models indicates that targeting N-methyl-d-aspartate (NMDA) receptor (NMDAR)-mediated glutamatergic toxicity might mitigate rmTBI-induced neurologic deficits. However, there is a paucity of preclinical or clinical data regarding NMDAR antagonist efficacy in the rmTBI setting. To test whether NMDAR antagonist therapy improves outcomes after rmTBI, mice were subjected to rmTBI injury (4 injuries in 4 days) and randomized to treatment with the NMDA antagonist memantine or with vehicle...
April 12, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28399551/risks-factors-for-reoperation-in-patients-treated-surgically-for-degenerative-spondylolisthesis-a-subanalysis-of-the-8-year-data-from-the-sport-trial
#2
Michael C Gerling, Dante Leven, Peter G Passias, Virgnie Lafage, Kristina Bianco, Alexandra Lee, Tamara S Morgan, Jon D Lurie, Tor D Tosteson, Wenyan Zhao, Kevin F Spratt, Kristen Radcliff, Thomas J Errico
STUDY DESIGN: Retrospective analysis of prospective data from the degenerative spondylolisthesis (DS) arm of the Spine Patient Outcomes Research Trial. OBJECTIVE: To identify risk factors for reoperation in patients treated surgically for DS and compare outcomes between patients who underwent reoperation with non-reoperative patients. SUMMARY OF BACKGROUND DATA: Several studies have examined outcomes following surgery for DS, but few have identified risk factors for reoperation...
April 10, 2017: Spine
https://www.readbyqxmd.com/read/28387560/clinical-evaluation-of-the-concussed-athlete-a-view-from-the-sideline
#3
Margot Putukian
CONTEXT: The sideline assessment of concussion is challenging, given its variable presentations, the limited sensitivity and specificity of sideline assessment tools, and how the presentation of the injury evolves over time. In addition, the diagnostic process, as well as the tools used to assess and manage concussion, continue to progress as research and what we know about concussion advance. This paper focuses on the initial assessment on the sideline by reviewing the concussion-evaluation literature, drawing from clinical experience to emphasize a standardized approach, and underscoring the importance of both familiarity with the athlete and clinical judgment...
March 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28387557/a-physiological-approach-to-prolonged-recovery-from-sport-related-concussion
#4
John Leddy, John G Baker, Mohammad Nadir Haider, Andrea Hinds, Barry Willer
Management of the athlete with postconcussion syndrome (PCS) is challenging because of the nonspecificity of PCS symptoms. Ongoing symptoms reflect prolonged concussion pathophysiology or conditions such as migraine headaches, depression or anxiety, chronic pain, cervical injury, visual dysfunction, vestibular dysfunction, or some combination of these. In this paper, we focus on the physiological signs of concussion to help narrow the differential diagnosis of PCS in athletes. The physiological effects of exercise on concussion are especially important for athletes...
March 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28327371/longitudinal-changes-in-linguistic-complexity-among-professional-football-players
#5
Visar Berisha, Shuai Wang, Amy LaCross, Julie Liss, Pamela Garcia-Filion
Reductions in spoken language complexity have been associated with the onset of various neurological disorders. The objective of this study is to analyze whether similar trends are found in professional football players who are at risk for chronic traumatic encephalopathy. We compare changes in linguistic complexity (as indexed by the type-to-token ratio and lexical density) measured from the interview transcripts of players in the National Football League (NFL) to those measured from interview transcripts of coaches and/or front-office NFL executives who have never played professional football...
March 16, 2017: Brain and Language
https://www.readbyqxmd.com/read/28290466/incidence-of-acute-spinal-cord-injury-in-the-czech-republic-a-prospective-epidemiological-study-2006-2015
#6
J Kriz, M Kulakovska, H Davidova, M Silova, A Kobesova
STUDY DESIGN: A prospective study. OBJECTIVES: Analysis of epidemiological data about acute spinal cord injury (SCI) in the Czech Republic over a period of 10 years (2006-2015). METHODS: A data collection system was implemented in the rehabilitation centres which provides care to patients with acute SCI in the Czech Republic. The recorded variables are as follows: age at time of SCI; gender; cause of injury; neurological level of injury (NLI); and its severity (ASIA Impairment Scale (AIS))...
March 14, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28287034/exploration-of-us-men-s-professional-sport-organization-concussion-policies
#7
Graham Dean Cochrane, Matthew Owen, Joseph D Ackerson, Matthew H Hale, Sara Gould
Concussion policies are increasingly being developed and adopted among professional sports organizations. We sought to compare the policies of the National Hockey League (NHL), the National Basketball Association (NBA), the National Football League (NFL), and Major League Baseball (MLB). Our objective was to summarize each policy and evaluate the extent to which each policy is organization-specific and/or consistent with medical guidelines. We visited websites for the NHL, NBA, NFL, and MLB. We searched media articles reporting concussion policy...
March 22, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28262355/the-importance-of-a-neck-exam-in-sport-related-concussion-cervical-schwannoma-in-post-concussion-syndrome
#8
David M Langelier, Kathryn J Schneider, John Hurlbert, Chantel T Debert
OBJECTIVE: Few cases of cervical schwannoma have been reported following head trauma. The present case, involves a schwannoma of the C2 spinal nerve mimicking post-concussion symptoms following a sport-related concussion (SRC). DESIGN: Case study. SETTING: University of Calgary, Sport Medicine Clinic, Calgary, Alberta, Canada. RESULTS: We report a 28 year old, athlete who developed headache, dizziness, photophobia, and neck pain following a cycling accident...
January 17, 2017: Physical Therapy in Sport
https://www.readbyqxmd.com/read/28262354/effects-of-joint-stabilizers-on-proprioception-and-stability-a-systematic-review-and-meta-analysis
#9
REVIEW
Shashank Ghai, Matthew Driller, Ishan Ghai
OBJECTIVE: The current review and meta-analysis systematically investigated the effect of joint stabilizers on proprioception, postural stability, and neurological activity. METHODS: Systematic identification of published literature was performed on online databases; Scopus, PEDro, SportDiscus, and EMBASE, followed by a critical PEDro methodological quality appraisal. Data from the studies were extracted and summarized in a tabular format. RESULTS: Of 2954 records, 50 studies, involving 1443 participants met our inclusion criteria...
May 18, 2016: Physical Therapy in Sport
https://www.readbyqxmd.com/read/28257619/complaints-of-upper-extremity-numbness-and-tingling-relieved-with-dry-needling-of-the-teres-minor-and-infraspinatus-a-case-report
#10
Elizabeth Lane, Derek Clewley, Shane Koppenhaver
Study Design Case report. Background Abnormal sensation, such as numbness or tingling, is traditionally thought to originate from neural compression. There is limited evidence to support reports of abnormal sensation arising from a trigger point. Case Description The patient was a 60-year-old female with primary complaints of right shoulder pain and secondary complaints of neck pain and right upper extremity numbness. Cervical spine neurological examination was unremarkable, and manual examination did not reproduce the patient's arm numbness or tingling symptoms...
March 3, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28229571/transnasal-transsphenoidal-brain-injury-by-a-fencing-foil-an-unusual-case-report-and-brief-literature-review
#11
Rafet Özay, Mehmet S Balkan, Çağhan Tönge, Zeki Şekerci
BACKGROUND: In this report, the authors present an unusual case of a 10-year-old child who suffered a severe headache and rhinorrhea that occurred as a result of fencing foil sports injury via transnasal-transsphenoidal (TNTS) pathway. METHODS: Following to trauma, the child had shown neurological symptoms such a pupil dilatation, change in consciousness and mild hemiparesia. Imaging demonstrated destruction of bone structures including posterior wall of sphenoid sinus and anterosuperior part of sella turcica, and also a contusion at right thalamic region...
February 22, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28214540/cognitive-performance-of-male-and-female-c57bl-6j-mice-after-repetitive-concussive-brain-injuries
#12
Alexander G Velosky, Laura B Tucker, Amanda H Fu, Jiong Liu, Joseph T McCabe
In contact sports, repetitive concussive brain injury (rCBI) is the prevalent form of head injury seen in athletes. The need for effective treatment is urgent as rCBI has been associated with a host of cognitive, behavioral and neurological complaints. There has been a growing trend in the use of female animals in pre-clinical research, but few studies have investigated possible sex differences following rCBI. The goal of the current study was to determine any differences between male and female C57BL/6J mice on assessments of learning and memory after repetitive concussive injury...
May 1, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28196030/physical-activities-and-lifestyle-factors-related-to-adolescent-idiopathic-scoliosis
#13
Kota Watanabe, Takehiro Michikawa, Ikuho Yonezawa, Masashi Takaso, Shohei Minami, Shigeru Soshi, Takashi Tsuji, Eijiro Okada, Katsumi Abe, Masamichi Takahashi, Keiko Asakura, Yuji Nishiwaki, Morio Matsumoto
BACKGROUND: In addition to genetic factors, environmental and lifestyle factors are thought to play an important role in the onset of adolescent idiopathic scoliosis (AIS). This cross-sectional study was conducted to explore lifestyle factors related to AIS. METHODS: This study included 2,759 Japanese female junior high school students who planned a secondary screening after an initial moiré topography screening indicated possible scoliosis. The students and their mothers, or guardians, were asked to fill out a questionnaire consisting of 38 questions about demographic factors, lifestyle-related factors, social factors, household environment, participation in sports, health status, and factors related to the mother's pregnancy and delivery...
February 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28195230/epidemiology-of-traumatic-spinal-cord-injury-in-galicia-spain-trends-over-a-20-year-period
#14
A Montoto-Marqués, M E Ferreiro-Velasco, S Salvador-de la Barrera, V Balboa-Barreiro, A Rodriguez-Sotillo, R Meijide-Failde
STUDY DESIGN: Observational study with prospective and retrospective monitoring. OBJECTIVE: To describe the epidemiological and demographic characteristics of traumatic spinal cord injury (TSCI), and to analyze its epidemiological changes. SETTING: Unidad de Lesionados Medulares, Complejo Hospitalario Universitario A Coruña, in Galicia (Spain). METHODS: The study included patients with TSCI who had been hospitalized between January 1995 and December 2014...
February 14, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28180920/injury-mechanism-of-midfacial-fractures-in-football-causes-in-over-40-typical-neurological-symptoms-of-minor-brain-injuries
#15
Volker Krutsch, Markus Gesslein, Oliver Loose, Johannes Weber, Michael Nerlich, Axel Gaensslen, Viktor Bonkowsky, Werner Krutsch
PURPOSE: The injury mechanisms of midfacial fractures may be typical causes of concussion, but hardly any scientific data on midfacial injuries sustained in football are available. Head and brain trauma represent frequent injuries in athletes of different sports that require appropriate treatment by sports and trauma physicians. This study investigated the management of midfacial fractures in football and the association of such fractures with concomitant brain injury. METHODS: In a prospective cohort study lasting 24 months (2012 to 2013), midfacial injuries of football players were analysed with regard to the injury mechanisms, first aid procedures on the field, treatment and return-to-play...
February 8, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28162172/-radiographic-and-clinical-assessment-of-supracondylar-humeral-fractures-resulted-from-sports-in-children
#16
Z J Liu, S N Pan, L J Zhang
Objective: To investigate the radiographic and clinical assessment for supracondylar humeral fractures resulted from sports in children. Methods: The medical records of 166 patients with displaced supracondylar humerus fractures treated in Shengjing Hospital of China Medical University from January 2015 to December 2015 were reviewed.The etiology of 56 of 166 cases was relevant to the sports.Medical records of 56 of 166 patients were reviewed, incluidng gender, the mean age of patient at the time of surgery, the mean duration of injury, radiographic assessment based on the anteroposterior (AP) and lateral radiographs of the elbow, neurologic injury, the Mayo Elbow Performance Score (MEPS) and the criteria of Flynn...
January 17, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28146015/reoperation-for-recurrent-intervertebral-disc-herniation-in-the-spine-patient-outcomes-research-trial-analysis-of-rate-risk-factors-and-outcome
#17
Robert W Abdu, William A Abdu, Adam M Pearson, Wenyan Zhao, Jon D Lurie, James N Weinstein
STUDY DESIGN: This study was a post-hoc subgroup analysis of prospectively collected data in the Spine Patient Outcomes Research Trial (SPORT). OBJECTIVE: Determine the risk factors for and to compare the outcomes of patients undergoing revision disc excision surgery in SPORT. SUMMARY OF BACKGROUND DATA: Risk factors for reherniation and outcomes after revision surgery have not been well-studied. This information is critical for proper patient counseling and decision making...
January 31, 2017: Spine
https://www.readbyqxmd.com/read/28141723/anxiety-associated-with-asthma-exacerbations-and-overuse-of-medication-the-role-of-cultural-competency
#18
Yousuke T Horikawa, Tina Y Udaka, Janet K Crow, John I Takayama, Martin T Stein
Toshi, a 14-year-old Japanese boy, had uncontrolled asthma after relocating from Japan with his family 1 year ago. In Japan, he was diagnosed with moderate, persistent asthma, which was controlled with salmeterol and albuterol on an as needed basis. Since moving to the United States, Toshi complained of frequent dyspnea.Initially, he was seen by a Japanese physician who prescribed 200 mg of fluticasone 3 times a day and albuterol nebulization as needed. When Toshi came to the Pediatric Primary Care Clinic, he reported using his nebulizer up to 25 times daily...
February 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28116463/-music-pulse-heart-and-sport
#19
REVIEW
E R Gasenzer, R Leischik
Music, with its various elements, such as rhythm, sound and melody had the unique ability even in prehistoric, ancient and medieval times to have a special fascination for humans. Nowadays, it is impossible to eliminate music from our daily lives. We are accompanied by music in shopping arcades, on the radio, during sport or leisure time activities and in wellness therapy. Ritualized drumming was used in the medical sense to drive away evil spirits or to undergo holy enlightenment. Today we experience the varied effects of music on all sensory organs and we utilize its impact on cardiovascular and neurological rehabilitation, during invasive cardiovascular procedures or during physical activities, such as training or work...
January 23, 2017: Herz
https://www.readbyqxmd.com/read/28114247/neuroendocrine-dysfunction-in-a-young-athlete-with-concussion-a-case-report
#20
David M Langelier, Gregory A Kline, Chantel T Debert
An 18-year-old female ringette and basketball player presented to our sport concussion clinic 27 months after concussion with fatigue, headache, exercise intolerance, polyuria, nocturia, and difficulties concentrating. Her history was remarkable for 4 previous concussions. Her neurologic examination was normal. Neuroendocrine screen including thyroid function, morning cortisol, glucose, and insulin-like growth factor-1 (screening test for growth hormone deficiency) were normal. Further testing for growth hormone deficiency with an insulin hypoglycemia test revealed severe growth hormone deficiency...
January 20, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
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