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gastrectomy D2

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https://www.readbyqxmd.com/read/29785081/pressurized-intraperitoneal-aerosol-chemotheprapy-after-misdiagnosed-gastric-cancer-case-report-and-review-of-the-literature
#1
Maciej Nowacki, Dariusz Grzanka, Wojciech Zegarski
We report the first application of pressurized intraperitoneal aerosol chemotherapy (PIPAC) as a rescue therapy before palliative D2 gastrectomy combined with liver metastasectomy performed in a 49-year-old woman with peritoneal carcinomatosis who was primarily diagnosed with and underwent surgery for a Krukenberg tumor. The PIPAC procedure was performed with the use of cisplatin at 7.5 mg/m2 and doxorubicin at 1.5 mg/m2 for 30 min at 37 °C. Eight weeks after the PIPAC procedure, the patient underwent open classic D2 gastrectomy with the creation of a Roux-en-Y anastomosis (RNY) combined with liver metastasectomy...
May 21, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29777355/reduced-port-totally-robotic-distal-subtotal-gastrectomy-with-lymph-node-dissection-for-gastric-cancer-a-modified-technique-using-single-site-%C3%A2-and-two-additional-ports
#2
Won Jun Seo, Taeil Son, Chul Kyu Roh, Minah Cho, Hyoung-Il Kim, Woo Jin Hyung
BACKGROUND: Reduced-port laparoscopic gastrectomy further minimizes the invasiveness of laparoscopic gastrectomy, thereby improving patient quality of life. However, suboptimal ergonomics and visualization are challenges to performing reduced-port laparoscopy. As the application of a robotic surgical system may help overcome these challenges, the present study was performed to evaluate the short-term outcomes of reduced-port totally robotic distal subtotal gastrectomy. METHOD: An initial 40 consecutive gastric cancer patients treated with reduced-port totally robotic distal subtotal gastrectomy with lymph node dissection from February 2016 to February 2017 were retrospectively reviewed...
May 18, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29774939/-feasibility-and-preliminary-technical-experience-of-single-incision-plus-one-port-laparoscopic-total-gastrectomy-combined-with-%C3%AF-shaped-esophagojejunal-anastomosis-in-surgical-treatment-of-gastric-cancer
#3
Guangsheng Du, Enlai Jiang, Yuan Qiu, Wensheng Wang, Shuai Wang, Yunbo Li, Ke Peng, Xiang Li, Hua Yang, Weidong Xiao
OBJECTIVE: To explore the feasibility, safety, and preliminary technical experience of single incision plus one port laparoscopic total gastrectomy combined with π-shaped esophagojejunal anastomosis (SILT-π) in the surgical treatment of gastric cancer. METHODS: Clinical data of 5 gastric cancer patients undergoing SILT-π operation at the Department of General Surgery, The Second Affiliated Hospital of the Army Medical University from August to October 2017 were retrospectively analyzed...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29766446/prognostic-significance-of-post-operative-morbidity-severity-score-after-potentially-curative-d2-gastrectomy-for-carcinoma
#4
Arfon Powell, Alexandra Harriet Coxon, Neil Patel, David Chan, Adam Christian, Wyn Lewis
BACKGROUND: Survival and relapse after gastric cancer surgery are largely attributed to tumor biology and surgical radicality; yet, other prognostic factors have been reported, including respiratory sepsis and anastomotic leakage, but not global morbidity severity score (MSS). The hypothesis tested was that MSS would be associated with both disease-free (DFS) and overall survival (OS). METHODS: Consecutive 373 patients undergoing potentially curative surgery for gastric adenocarcinoma between 2004 and 2016 in a UK cancer network were studied...
May 15, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29764518/a-novel-nomogram-individually-predicting-disease-specific-survival-after-d2-gastrectomy-for-advanced-gastric-cancer
#5
Wei Wang, Zhe Sun, Jing-Yu Deng, Xiao-Long Qi, Xing-Yu Feng, Cheng Fang, Xing-Hua Ma, Zhen-Ning Wang, Han Liang, Hui-Mian Xu, Zhi-Wei Zhou
BACKGROUND: Few studies have shown nomograms that may predict disease-specific survival (DSS) probability after curative D2 gastrectomy for advanced gastric cancer (AGC), particularly among Chinese patients. This study sought to develop an elaborative nomogram that predicts long-term DSS for AGC in Chinese patients. METHODS: A retrospective study was conducted on 6753 AGC patients undergoing D2 gastrectomy between January 1, 2000 and December 31, 2012 from three large medical hospitals in China...
May 15, 2018: Cancer communications
https://www.readbyqxmd.com/read/29761671/risk-factors-for-complications-of-total-subtotal-gastrectomy-for-gastric-cancer-prospectively-collected-based-on-the-clavien-dindo-classification-system
#6
Yehonatan Nevo, Yuri Goldes, Liran Barda, Roy Nadler, Mordechai Gutman, Avinoam Nevler
BACKGROUND: Recent studies have analyzed risk factors associated with complications after gastric cancer surgery using the Clavien-Dindo classification (CD). However, they have been based on Asian population cohorts (Chinese, Japanese, Korean). OBJECTIVES: To prospectively analyze all post-gastrectomy complications according to severity using CD classification and identify postoperative risk factors and complications. METHODS: We analyzed all gastrectomies for gastric cancer performed 2009-2014...
May 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29732359/mixed-adenoneuroendocrine-carcinoma-in-the-stomach-a-case-report-with-a-literature-review
#7
Ki Hyun Kim, Hyun Jung Lee, Si Hak Lee, Sun-Hwi Hwang
Mixed adenoneuroendocrine carcinoma (MANEC) is a rare disease that was first defined in the 2010 World Health Organization classification of endocrine tumors. We present the case of a 65-year-old man with an ulcerative depressed lesion measuring 3 cm in diameter and found in the lower gastric body. It was diagnosed as a MANEC, and we performed subtotal gastrectomy with D2 lymph node dissection. The patient is still alive, and no recurrence was observed at a 12-month follow-up. Most MANECs tend to have a poor prognosis...
May 2018: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/29727332/microsatellite-instability-and-programmed-cell-death-ligand-1-expression-in-stage-ii-iii-gastric-cancer-post-hoc-analysis-of-the-classic-randomized-controlled-study
#8
Yoon Young Choi, Hyunki Kim, Su-Jin Shin, Ha Yan Kim, Jinae Lee, Han-Kwang Yang, Woo Ho Kim, Young-Woo Kim, Myeong-Cherl Kook, Young Kyu Park, Hyung-Ho Kim, Hye Seung Lee, Kyung Hee Lee, Mi Jin Gu, Seung Ho Choi, SoonWon Hong, Jong Won Kim, Woo Jin Hyung, Sung Hoon Noh, Jae-Ho Cheong
OBJECTIVE: We investigated microsatellite instability (MSI) status and programed cell death ligand 1 (PD-L1) expression as predictors of prognosis and responsiveness to chemotherapy for stage II/III gastric cancer. BACKGROUND: The clinical implications of MSI status and PD-L1 expression in gastric cancer have not been well-elucidated. METHODS: Tumor specimens and clinical information were collected from patients enrolled in the CLASSIC trial-a randomized controlled study of capecitabine plus oxaliplatin-based adjuvant chemotherapy...
May 1, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29725766/the-anatomical-configuration-of-the-splenic-artery-influences-suprapancreatic-lymph-node-dissection-in-laparoscopic-gastrectomy-analysis-using-a-3d-volume-rendering-program
#9
Chunchao Zhu, Seong-Ho Kong, Tae-Han Kim, Shin-Hoo Park, Rene Ronson G Ang, Michele Diana, Luc Soler, Yun-Suhk Suh, Hyuk-Joon Lee, Jacques Marescaux, Hui Cao, Han-Kwang Yang
BACKGROUND: The aim of this study is to categorize splenic artery and vein configurations, and examine their influence on suprapancreatic lymph node (LN) dissection in laparoscopic gastrectomy. METHODS: Digital Imaging and Communications in Medicine images from 169 advanced cancer patients who underwent laparoscopic gastrectomy with D2 dissection were used to reconstruct perigastric vessels in 3D using a volume rendering program (VP Planning® ). Splenic artery and vein configuration were classified depending on the relative position of their lowest part in regard to the pancreas...
May 3, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29719906/totally-laparoscopic-versus-open-gastrectomy-for-gastric-cancer-a-matched-pair-analysis
#10
Kaja Ludwig, Sylke Schneider-Koriath, Uwe Scharlau, Holger Steffen, Daniela Möller, Jörn Bernhardt
BACKGROUND: Laparoscopic gastrectomy has been established for treatment of early gastric cancer (EGC) especially in Eastern Asian countries. Currently, it still needs evaluation for advanced gastric cancer (AGC, T ≥ 2). Difficulty is how far Asian study data are valid for western conditions. METHODS: Out of 502 patients who underwent gastric cancer surgery between 2003 and 2016 at Klinikum Suedstadt Rostock 90 patients were selected for a retrospective study to compare totally laparoscopic D2-gastrectomy (LG, n = 45) with open D2-gastrectomy (OG, n = 45)...
April 2018: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29709558/bursectomy-versus-omentectomy-alone-for-resectable-gastric-cancer-jcog1001-a-phase-3-open-label-randomised-controlled-trial
#11
Yukinori Kurokawa, Yuichiro Doki, Junki Mizusawa, Masanori Terashima, Hitoshi Katai, Takaki Yoshikawa, Yutaka Kimura, Shuji Takiguchi, Yasunori Nishida, Norimasa Fukushima, Yoshiaki Iwasaki, Masahide Kaji, Motohiro Hirao, Hiroshi Katayama, Mitsuru Sasako
BACKGROUND: The role of bursectomy, in which the peritoneal lining covering the pancreas and the anterior plane of the transverse mesocolon are dissected, has long been controversial for preventing peritoneal metastasis. We investigated the survival benefit of bursectomy in patients with resectable gastric cancer. METHODS: This phase 3, open-label, randomised controlled trial was done at 57 hospitals in Japan. Patients aged 20-80 years who had cT3(SS)-cT4a(SE) histologically proven gastric adenocarcinoma with an Eastern Cooperative Oncology Group performance status of 0 or 1 and body-mass index less than 30 kg/m2 and who did not have distant metastasis or bulky lymph nodes were randomly assigned (1:1) during surgery to receive omentectomy alone (non-bursectomy) or bursectomy...
April 27, 2018: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29700635/favorable-long-term-outcomes-of-one-year-adjuvant-s-1-monotherapy-for-pathological-stage-ii-or-iii-gastric-cancer-treated-at-a-high-volume-center
#12
Yosuke Kano, Manabu Ohashi, Naoki Hiki, Daisuke Takahari, Keisho Chin, Kensei Yamaguchi, Yasuo Tsuda, Yoshiaki Shoji, Itaru Yasufuku, Kojiro Eto, Satoshi Ida, Koshi Kumagai, Souya Nunobe, Takeshi Sano
BACKGROUND: One-year adjuvant S-1 monotherapy following D2 gastrectomy has been the Japanese treatment standard for pathological stage II or III gastric cancer since the Adjuvant Chemotherapy Trial of S-1 for Gastric Cancer (ACTS-GC) was concluded in 2007. Trial patients were selected according to the 13th edition of the Japanese classification (JC-13). The JC-13 and the TNM classification underwent major revisions in 2010 (JC-14/TNM-7). However, neither the recent therapeutic results for patients with stage II/III disease defined by the current system nor comparisons with the ACTS-GC-results have been reported...
April 26, 2018: Gastric Cancer
https://www.readbyqxmd.com/read/29698790/severity-of-complications-and-long-term-survival-after-laparoscopic-total-gastrectomy-with-d2-lymph-node-dissection-for-advanced-gastric-cancer-a-propensity-score-matched-case-control-study
#13
Zhengyan Li, Bin Bai, Yan Zhao, Deliang Yu, Bo Lian, Yezhou Liu, Qingchuan Zhao
BACKGROUND: Increasing numbers of studies have shown that postoperative complication is a negative predictor of long-term survival outcomes in various malignancies. However, the impact of severity of complications on long-term survival for patients with gastric cancer still remains unclear. This study aimed to explore the relationship between the severity of complications and long-term survival outcomes after laparoscopic total gastrectomy (LTG) for advanced gastric cancer (AGC). METHODS: The study analyzed 571 patients with AGC who underwent LTG in a single institution between April 2008 and June 2015...
April 23, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29692629/robotic-versus-laparoscopic-gastrectomy-with-d2-lymph-node-dissection-for-advanced-gastric-cancer-a-propensity-score-matched-analysis
#14
Zhengyan Li, Jipeng Li, Bofei Li, Bin Bai, Yezhou Liu, Bo Lian, Qingchuan Zhao
Background: Robotic gastrectomy (RG) is a new surgical method alternative for gastric cancer. However, few studies have evaluated the outcomes of RG for advanced gastric cancer (AGC). Thus, the aim of this study was to compare the short-and long-term outcomes of RG and laparoscopic gastrectomy (LG) with D2 lymph node dissection for AGC. Patients and methods: We retrospectively evaluated 454 patients with AGC who underwent RG or LG with D2 lymph node dissection for AGC between August 2013 and March 2017...
2018: Cancer Management and Research
https://www.readbyqxmd.com/read/29662932/combined-extensive-esophageal-squamous-papillomas-and-florid-cardiac-gland-hyperplasia-in-a-patient-with-adenocarcinoma
#15
Takanori Suganuma, Han-Seung Yoon
We report a rare case of extensive esophageal squamous papillomas (ESPs) involving the entire esophagus and florid cardiac gland hyperplasia involving only the lower esophagus in a 39-year-old woman with heartburn and epigastric distress for the past 2 years. Previous esophagogastroduodenoscopy showed multiple ESPs involving the entire esophagus extending 38 cm from the esophageal orifice to the esophagogastric junction (EGJ). Additionally, prominent cardiac gland hyperplasia over the esophageal posterior wall was exhibited extending 12 cm from the mid-esophagus to the EGJ...
March 2018: GE Portuguese Journal of Gastroenterology
https://www.readbyqxmd.com/read/29650911/-a-case-of-advanced-gastric-cancer-with-multiple-liver-metastases-treated-with-curative-conversion-therapy-after-s-1-plus-cddp
#16
Yukito Shindo, Shinichiro Fukuda, Ryoko Kataoka, Nobutsuna Kuwamoto, Hitomi Takaishi, Yasuaki Miura, Ryoichi Hirayama, Ryo Otsuka, Shuji Saito, Rikiya Fujita
A57 -year-old man was diagnosed with advanced gastric cancer(adenocarcinoma[tub2/por1])with multiple(S3, S4, S5, S6, S8)liver and para-aortic lymph node metastases. The tumor was classified as cT4a, N3, M1, HEP, cStage IV, and the patient received chemotherapy with S-1 plus CDDP(SP). After 10 courses of SP, a CT scan revealed that the primary tumor and the metastases disappeared. The patient presented with cCR and underwent distal gastrectomy, D2 lymph node dissection, partial hepatic resection, and cholecystectomy...
March 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29650858/-a-case-of-unresectable-advanced-gastric-cancer-treated-by-seven-courses-of-chemotherapy-with-docetaxel-cisplatin-and-s-1followed-by-conversion-surgery-achieved-five-year-relapse-free-survival
#17
Tetsushi Nakajima, Haruhiko Cho, Yoichiro Okubo, Kazuki Kano, Yukio Maezawa, Kousuke Ikeda, Takanobu Yamada, Takashi Ogata, Takaki Yoshikawa
The patient is a 51-year-old man.Upper gastrointestinal endoscopy revealed gigantic type 3 gastric cancer.Enhanced abdominal CT demonstrated a gigantic mass of 15×7 cm in the stomach, and a large number of peritoneal dissemination with moderate amount of ascites.The patient was diagnosed with cT4aN3bM1(peritoneal dissemination), Stage IV gastric cancer(JPN ver8)and was treated by chemotherapy with docetaxel(40mg/m / 2 day 1)plus cisplatin(60mg/m2 day 1)plus S-1(80mg/m2 day 1-14).After 7 courses of chemotherapy, peritoneal dissemination was disappeared...
April 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29650843/-a-case-of-gastric-carcinoma-with-peritoneal-dissemination-treated-with-curative-resection-following-trastuzumab-plus-capecitabine-plus-cisplatin-combined-therapy
#18
Yusuke Matsuda, Satoshi Suzuki, Ritsuko Maehara, Yoshiko Matsuda, Shingo Kanaji, Masashi Yamamoto, Hiroshi Hasegawa, Koudai Yamashita, Takeru Matsuda, Taro Oshikiri, Yasuo Sumi, Tetsu Nakamura, Yoshihiro Kakeji
A 67-year-old man was referred to our hospital with a diagnosis of type 3 gastric cancer in lower third of the stomach. Computed tomography(CT)scan showed no distant metastasis, but peritoneal dissemination from gastric cancer. A laparoscopic exploration diagnosed pStage IV gastric cancer with peritoneal dissemination. Trastuzumab, capecitabine and cisplatin therapy was administered for initially unresectable gastric cancer. After 6courses of chemotherapy, primary lesion and lymph node metastasis shrank, and the peritoneal dissemination did not worsen by CT scan...
April 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29650837/-laparoscopic-distal-gastrectomy-for-elderly-patients-with-advanced-gastric-cancer-and-gastric-outlet-obstruction-a-case-report
#19
Kurumi Tsuchihashi, Ken Yuu, Satoshi Okumura, Sho Toyoda, Hiroshi Yasuda, Kansuke Yamamoto, Aya Ito, Naoto Mizumura, Hiroshi Tsuchihashi, Masao Ogawa, Masayasu Kawasaki, Masao Kameyama
A 90-year-old female patient was admitted to our hospital with a chief complaint of vomiting.Gastroscopy revealed type 3 gastric cancer and gastric outlet obstruction(GOO).Abdominal computed tomography revealed thickening of the antral wall and suggested the presence of 3 perigastric lymph node metastases, but there was no ascitic fluid or distant metastasis.The clinical diagnosis was T4a(SE)N2H0CYXP0M0, Stage III B, according to the Japanese Classification of Gastric Carcinoma.Her general conditions including kidney and cardiac function were good, we considered that she was able to tolerate radical distal gastrectomy...
April 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29650832/-a-case-of-long-term-survival-in-gastric-cancer-with-multiple-liver-metastases-successfully-treated-by-conversion-surgery-after-s-1-plus-cisplatin-combination-therapy
#20
Taichi Tatsubayashi, Hiroyuki Tanishima, Shinji Iwakura, Toshiji Tominaga, Masamichi Kimura, Tetsuya Horiuchi, Yoshihiko Hoshida
A 49-year-old man was diagnosed with advanced gastric cancer, with a chief complaint of epigastric discomfort. Computed tomography revealed multiple liver metastases. S-1 plus cisplatin therapy was administered as first-line chemotherapy, and after 4courses, the liver metastases markedly reduced. Total gastrectomy with D2 lymphadenectomy and a needle biopsy of segment 2 of the liver were performed. Histopathological examination revealed no viable cancer cells in the resected stomach, lymph nodes, or liver tissue...
April 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
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