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Urethral stricture

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https://www.readbyqxmd.com/read/29226987/protective-effect-of-platelet-rich-plasma-on-urethral-injury-model-of-male-rats
#1
Hasan H Tavukcu, Ömer Aytaç, Fatih Atuğ, Burçin Alev, Özge Çevik, Nurdan Bülbül, Ayşen Yarat, Şule Çetinel, Göksel Şener, Haluk Kulaksızoğlu
AIMS: Urethral stricture (US) formation is caused by fibrosis after excessive collagen formation following an injury or trauma to the urethra. In this study, we aimed to evaluate the effects of platelet-rich plasma (PRP) on a urethral injury (UI) model of male rats. METHODS: A UI model was used by applying a coagulation current to the urethras of male rats. There were four groups with six rats in each: control group, PRP applied to naive urethra, UI group, and UI with PRP application...
December 11, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29221931/urethral-rest-with-suprapubic-cystostomy-in-obliterative-or-nearly-obliterative-urethral-strictures-urethrographic-changes-and-implications-for-management
#2
T Moncrief, R A Gor, R A Goldfarb, S Jarosek, S P Elliott
OBJECTIVE: Precise pre-operative urethral stricture characterization is important for surgical planning. A period of urethral rest by suprapubic cystostomy tube may aid in stricture characterization and may affect the surgical approach. We compare the radiographic characterization of anterior urethral strictures by fellowship-trained reconstructive urologists before and after a period of urethral rest. We then determine how this changed the planned operative approach. METHODS: We queried our prospectively maintained urethroplasty database at the University of Minnesota for men with anterior urethral stricture who had retrograde urethrogram (RUG) and voiding cystourethrogram (VCUG) both before and after pre-operative suprapubic cystostomy tube (SPC) placement (n=29)...
December 5, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29211405/high-intensity-focused-ultrasound-hifu-as-salvage-therapy-for-radio-recurrent-prostate-cancer-predictors-of-disease-response
#3
Shawn Dason, Nathan C Wong, Christopher B Allard, Jen Hoogenes, William Orovan, Bobby Shayegan
BACKGROUND: Some men with localized radio-recurrent prostate cancer may benefit from salvage high-intensity focused ultrasound (HIFU). Herein, we describe oncologic outcomes and predictors of disease response after salvage whole gland HIFU from our prospective cohort. MATERIALS AND METHODS: Patients with localized radio-recurrent prostate cancer were prospectively enrolled from January 2005 to December 2014. Participants had to meet both biochemical and histological definitions of recurrence...
December 7, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29211404/management-of-long-segment-anterior-urethral-stricture-%C3%A2-8cm-using-buccal-mucosal-bm-graft-and-penile-skin-ps-flap-outcome-and-predictors-of-failure
#4
Gamal A Alsagheer, Atef Fathi, Mohamed Sayed Abdel-Kader, Ahmed M Hasan, Omar Mohamed, Osama Mahmoud, Ahmad Abolyosr
PURPOSE: To evaluate the surgical outcome and predictors of failure of substitution urethroplasty using either dorsal onlay buccal mucosal (BM) graft or ventral onlay penile skin flap (PS) for anterior urethral stricture ≥ 8cm. PATIENTS AND METHODS: Between March 2010 and January 2016, 50 patients with anterior urethral stricture ≥ 8 cm were treated at our hospital. The surgical outcome and success rate were assessed. The predictors of failure were analyzed using multivariate analysis...
December 7, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29209754/-stricture-of-the-vesicourethral-anastomosis-after-radical-prostatectomy
#5
REVIEW
V Beck, M Apfelbeck, M Chaloupka, A Kretschmer, F Strittmatter, S Tritschler
BACKGROUND: The development of a stricture of the vesicourethral anastomosis is a serious complication after radical prostatectomy. Strictures occur in 5-8% of patients after radical prostatectomy. SYMPTOMS: Usually the clinical symptoms include an irritative and obstructive component similar to benign prostatic hyperplasia. In rare cases, patients suffer from partial or complete stress incontinence as a result of the anastomotic stricture. DIAGNOSTICS: The diagnostic workup is similar to the procedure for urethral strictures...
December 5, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/29204160/does-supplemental-external-beam-radiation-therapy-impact-urinary-bowel-and-erectile-function-following-permanent-prostate-brachytherapy-results-of-two-prospective-randomized-trials
#6
Gregory S Merrick, Ava Tennant, Kent E Wallner, Robert Galbreath, Wayne M Butler, Ryan Fiano, Edward Adamovich
Purpose: To evaluate the impact of supplemental external beam radiation therapy (EBRT) prior to permanent prostate brachytherapy on long term urinary, bowel, and erectile function. Material and methods: Patient administered urinary, bowel, and erectile quality of life (QoL) instrument were obtained prior to treatment and following brachytherapy. The study population was comprised of the 457 patients who were alive as of June 2016, had been randomized to two markedly different supplemental EBRT dose regimens and a third arm without supplemental EBRT, and had completed the June 2016 QoL survey...
October 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29201515/a-novel-method-in-decision-making-for-the-diagnosis-of-anterior-urethral-stricture-using-methylene-blue-dye
#7
Pankaj Joshi, Cevdet Kaya, Sandesh Surana, Devang J Desai, Hazem Orabi, Subramanian Iyer, Sanjay B Kulkarni
Objective: The use of methylene blue dye (MB) to highlight anatomical structures in urology has been well-established. Urethral stricture may extend about a centimeter beyond the abnormal area seen on urethrogram. Although the current literature suggests a tension-free and end- to- end anastomosis after excision of the strictured urethral segment with spongiofibrosis and surrounding corpus spongiosum in short bulbar strictures, some centers dealing with urethroplasty prefer anastomosis for short bulbar strictures while others prefer augmentation...
December 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/29198998/surgical-approaches-and-long-term-outcomes-in-adults-with-complex-re-operative-hypospadias-repair
#8
Christopher D Morrison, Davide P Cinà, Christopher M Gonzalez, Matthias D Hofer
PURPOSE: Patients with failed hypospadias repair are a challenging population for both pediatric and reconstructive urologists. In this study, we describe our long-term outcomes and factors associated with complications in repeat hypospadias repairs. MATERIAL AND METHODS: A retrospective review of 32 adult patients with a history of hypospadias repair who required subsequent urethroplasty between 2002 and 2012 was performed. Presenting complaint, past medical and surgical history, demographic data, surgical approach, intraoperative findings, and complications were collected and analyzed...
November 30, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29198583/substitution-urethroplasty-with-closure-versus-nonclosure-of-the-buccal-mucosa-graft-harvest-site-a-randomized-controlled-trial-with-a-detailed-analysis-of-oral-pain-and-morbidity
#9
Armin Soave, Roland Dahlem, Hans O Pinnschmidt, Michael Rink, Jessica Langetepe, Oliver Engel, Luis A Kluth, Birte Loechelt, Philip Reiss, Sascha A Ahyai, Margit Fisch
BACKGROUND: Optimal surgical management of the buccal mucosa harvest site in patients with urethral stricture disease during buccal mucosa graft urethroplasty (BMGU) remains controversial. OBJECTIVE: To analyze in detail intensity and quality of pain as well as oral morbidity following closure (C) versus nonclosure (NC) of the donor site. DESIGN, SETTING, AND PARTICIPANTS: Randomized controlled trial on 135 patients treated with BMGU between October 15, 2014 and December 18, 2015...
November 30, 2017: European Urology
https://www.readbyqxmd.com/read/29191643/incidence-of-stress-urinary-incontinence-following-posterior-urethroplasty-for-radiation-induced-urethral-strictures
#10
Paul H Chung, Paige Esposito, Hunter Wessells, Bryan B Voelzke
OBJECTIVES: To identify the frequency of de novo SUI after posterior excision and primary anastomotic (EPA) urethroplasty in patients with radiation-induced urethral strictures (RIUS) and compare to patients with pelvic fracture urethral injuries (PFUI). METHODS: A retrospective review was conducted among patients who underwent successful posterior EPA urethroplasty between 2008 and 2016 for RIUS from prostate cancer or PFUI from blunt trauma. Only patients with an intact bladder neck on imaging were included...
November 27, 2017: Urology
https://www.readbyqxmd.com/read/29189873/-diagnostic-workup-of-urethral-strictures
#11
REVIEW
M Chaloupka, V Beck, A Kretschmer, S Tritschler, C G Stief, F Strittmatter
Urethral stricture is a narrowing of the urethra due to scar tissue. It causes obstructive voiding dysfunction and can lead to long-term damage of the entire urinary tract. The probability of therapeutic success is dampened by a high rate of recurrence. Therefore, a careful taking of the patient's history and further diagnostics are crucial for finding the appropriate form of therapy. This review highlights the clinical presentation and diagnostic workup of urethral strictures.
November 30, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/29188324/total-vaginectomy-and-urethral-lengthening-at-time-of-neourethral-prelamination-in-transgender-men
#12
Carlos A Medina, Lydia A Fein, Christopher J Salgado
INTRODUCTION AND HYPOTHESIS: For transgender men (TGM), gender-affirmation surgery (GAS) is often the final stage of their gender transition. GAS involves creating a neophallus, typically using tissue remote from the genital region, such as radial forearm free-flap phalloplasty. Essential to this process is vaginectomy. Complexity of vaginal fascial attachments, atrophy due to testosterone use, and need to preserve integrity of the vaginal epithelium for tissue rearrangement add to the intricacy of the procedure during GAS...
November 29, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/29182032/squamous-cell-carcinoma-of-the-bulbar-urethra-accompanied-by-lichen-sclerosus-a-case-report
#13
Xufeng Peng, Hailin Guo, Chongrui Jin, Lin Wang, Yinglong Sa
Squamous cell carcinoma (SCC) of the bulbar urethra accompanied by lichen sclerosus (LS) is rarely reported. This study reports the case of a 56-year-old man with urethral squamous cell carcinoma (USCC) accompanied by a long history of genital LS. The man presented with a painful perineal mass and had a long-term history of urethral strictures and urethral dilatation. The patient developed a periurethral abscess that expanded to the perineum and formed an urethrocutaneousperineal fistula. An organ-sparing perineal resection and fistulectomy was performed according to the patient's wishes...
November 1, 2017: American Journal of Men's Health
https://www.readbyqxmd.com/read/29178533/urethral-complications-after-transgender-phalloplasty-and-strategies-to-treat-them-and-minimize-their-occurrence
#14
REVIEW
Richard A Santucci
BACKGROUND: Radial forearm free flap phalloplasty (RFFP) is the current standard of care for most FTM gender confirmation surgeries. This procedure is associated with a rate of urethral stricture as high as 51%, which falls only to 23-35% even among the most experienced contemporary surgeons. While some modifications have been proposed to combat this high complication rate, it still remains a major source of lasting morbidity. METHODS: Literature review of RFFP literature...
November 27, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/29175892/interrupted-versus-continuous-suturing-for-vesicourethral-anastomosis-during-radical-prostatectomy-protocol-for-a-systematic-review-and-meta-analysis
#15
Karl Friedrich Kowalewski, Christian Tapking, Svetlana Hetjens, Felix Nickel, Philipp Mandel, Manuel Ritter, Maximilian Christian Kriegmair
INTRODUCTION: Radical prostatectomy is the mainstay of treatment for prostate cancer. The vesicourethral anastomosis is a critical step, which most likely impacts urinary continence and urethral stenosis. To date, it still remains unclear whether interrupted and continuous suturing for the anastomosis have different outcomes. Therefore, the aim of this systematic review and meta-analysis is to compare different suture techniques for vesicourethral anastomosis in terms of surgical and functional parameters...
November 25, 2017: BMJ Open
https://www.readbyqxmd.com/read/29175024/y-type-urethral-duplication-with-rectal-implantation-of-the-urethra-which-is-the-best-approach
#16
Antonio Macedo, Sérgio Leite Ottoni, Marcela Leal da Cruz, Jorge Antonio Pompermaier, Maria Isabel S Silva, Riberto Liguori, Gilmar Garrone
INTRODUCTION: Y-type urethral duplication describes the condition in which a functional urethra is implanted in the rectum, and there is also a dysplastic topic urethra which produces mostly urinary dribbling. These patients are at risk of urinary tract complications and UTI. We aimed to present the surgical steps of a case treated by ASTRA approach in which we separated the urethra from the rectum and created a perineal urethrostomy. MATERIAL AND METHODS: We treated a 5-month-old boy with Y-type (IIA-2) urethral duplication, in whom the orthotopic urethra was patent just in the penile segment...
November 10, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29171166/outcomes-of-asian-patients-with-localized-prostate-cancer-treated-with-combined-intensity-modulated-radiation-therapy-imrt-and-high-dose-rate-hdr-brachytherapy-a-single-institution-experience
#17
Ivy Wei Shan Ng, Jeremy Chee Seong Tey, Yu Yang Soon, Michelle Shu Fen Tseng, Desiree Chen, Keith Hsiu Chin Lim
AIM: External beam radiotherapy (EBRT) followed by high dose rate (HDR) brachytherapy boost has demonstrated minimal toxicities and improved disease control rate compared with EBRT alone in observational and randomized studies with predominantly Caucasian patients. This study aims to report the outcomes of patients treated with this approach in our predominantly Asian population. METHODS: Medical records for patients with localized prostate cancer who received combined EBRT delivered via intensity modulated radiotherapy (IMRT) technique followed by HDR brachytherapy boost were retrospectively reviewed...
November 23, 2017: Asia-Pacific Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29162067/necrotizing-fasciitis-after-high-dose-rate-brachytherapy-and-external-beam-radiation-for-prostate-cancer-a-case-report
#18
Shimpei Yamashita, Yasuo Kohjimoto, Akinori Iba, Kazuro Kikkawa, Isao Hara
BACKGROUND: In recent years, the delayed side effects associated with radiotherapy for prostate cancer have drawn the interest of urologists. Although urosymphyseal fistula is one of these delayed side effects, this serious complication is rarely described in literature and is poorly recognized. CASE PRESENTATION: We report our experience in treating a 77-year-old male patient with necrotizing fasciitis after high-dose rate brachytherapy plus external beam radiation for prostate cancer...
November 21, 2017: BMC Urology
https://www.readbyqxmd.com/read/29158171/pubo-urethral-stump-angle-measured-on-preoperative-mri-predicts-urethroplasty-type-for-pelvic-fracture-urethral-injury-repair
#19
Akio Horiguchi, Hiromi Edo, Shigeyoshi Soga, Masayuki Shinchi, Ayako Masunaga, Keiichi Ito, Tomohiko Asano, Hiroshi Shinmoto, Ryuichi Azuma
OBJECTIVES: To examine whether the type of delayed urethroplasty required for pelvic fracture urethral injury (PFUI), which is not easily predicted from conventional urethrography findings, can be predicted from preoperative magnetic resonance imaging (MRI) results. PATIENTS AND METHODS: Records of 74 male patients with PFUI who underwent MRI of the pelvis at least 3 months after injury and, subsequently, delayed anastomotic urethroplasty were retrospectively analyzed...
November 17, 2017: Urology
https://www.readbyqxmd.com/read/29151330/analysis-of-recurrent-urethral-strictures-due-to-iatrogenic-urethral-trauma
#20
Fuat Kızılay, Adnan Şimşir, Ceyhun Özyurt
Background/aim: We aimed to analyze the effects of stricture location, etiology, age, and catheterization time on recurrence rate and recurrence time in patients who underwent direct vision internal urethrotomy (DVIU) for urethral strictures. Materials and methods: Patients were divided into three groups according to the location of the stricture: penile urethra, membranous urethra, and prostatic urethra strictures. Patients were also divided into three groups according to etiologic factors: strictures secondary to endoscopic procedures, urethral catheterization, and open or radical prostatectomy (anastomotic strictures were included in this group)...
November 13, 2017: Turkish Journal of Medical Sciences
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