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Urethral stricture

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https://www.readbyqxmd.com/read/28442385/the-immediate-management-of-pelvic-fracture-urethral-injury-endoscopic-realignment-or-cystostomy
#1
Qingsong Zou, Shukui Zhou, Kaile Zhang, Naixing Yang, Qiang Fu
PURPOSE: To determine whether endoscopic realignment or cystostomy provides the best immediate management of pelvic fracture urethral injury (PFUI). MATERIALS AND METHODS: We retrospectively reviewed 590 patients with PFUI and included 522 cases due to strict criteria: endoscopic realignment group (129 patients) and cystostomy (393 patients). Data regarding stricture formation, stricture length, intervention technique, and long-term functional outcomes were analyzed...
April 22, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28434634/hypospadias-surgery-in-england-higher-volume-centres-have-lower-complication-rates
#2
David J Wilkinson, Patrick A Green, Shanthi Beglinger, Jessica Myers, Rachel Hudson, David Edgar, Simon E Kenny
INTRODUCTION: Hypospadias surgery has progressed steadily over recent years. There remains considerable variation in the operative management of boys with hypospadias in the UK, and it is therefore difficult to identify acceptable standards with regards to reoperation rates. OBJECTIVE: To determine the frequency of reoperations and complications from all centres performing hypospadias surgery in England and to identify variables that influence outcome. METHODS: All children undergoing NHS hypospadias surgery in England between 1999 and 2009 were identified using the Hospital Episode Statistics database...
February 20, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28432540/preliminary-clinical-study-on-non-transecting-anastomotic-bulbomembranous-urethroplasty
#3
Wei Le, Chao Li, Jinfu Zhang, Denglong Wu, Bo Liu
This study aims to investigate the effect of non-transecting anastomotic urethroplasty for treatment of posterior urethral stricture. A total of 23 patients with traumatic posterior urethral stricture were enrolled and then divided into two groups. In one group, 12 patients underwent non-transecting anastomotic urethroplasty. In the other group, 11 patients underwent conventional posterior urethra end-to-end anastomosis. The effect of operation was evaluated using the following parameters: the bleeding amount during operation, operation time, IIEF-5 scores after operation, maximum flow rate (Qmax), and rating scale of quality of life (QoL)...
April 22, 2017: Frontiers of Medicine
https://www.readbyqxmd.com/read/28429926/the-efficacy-of-intraurethral-lidocaine-in-optical-internal-urethrotomy-for-anterior-urethral-stricture-a-multicenter-study
#4
Nedim Y Cem, Yıldız Yildiray, Cem Ö Berat, Melih S Mehmet, Gökhan D Ömer, Metin H Ahmet, Özyuvalı Ekrem, Ayyıldız Ali
BACKGROUND: Male anterior urethral strictures can be treated successfully with the help of optical internal urethrotomy (OIU) and is usually performed under general or regional anaesthesia. In this study, we determined the efficacy of intraurethral lidocaine in OIU for anterior urethral stricture in an outpatient setting. METHODS: 157 patients with anterior urethral strictures underwent OIU under local urethral anaesthesia with lidocaine. Optical urethrotomy was performed with a cold-cutting knife...
April 20, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/28405763/five-year-outcomes-of-thulium-vapoenucleation-of-the-prostate-for-symptomatic-benign-prostatic-obstruction
#5
A J Gross, A K Orywal, B Becker, C Netsch
INTRODUCTION AND OBJECTIVES: To assess the 5-year outcomes of thulium vapoenucleation of the prostate (ThuVEP) in patients with benign prostatic obstruction (BPO) retrospectively. METHODS: Five-hundred patients were treated with ThuVEP between January 2007 and January 2010 at our institution. Patients were reassessed 1 and 5-years after ThuVEP with International Prostate Symptom Score (IPSS), Quality of Life (QoL), urinary peak flow (Qmax), postvoid residual volume (PVR), PSA and prostate volume...
April 12, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28403586/urethroplasty-with-dorsal-buccal-mucosa-graft-is-it-still-the-method-of-choice-in-long-term-urethral-stenosis
#6
Carlo Pavone, Dario Fontana, Ninfa Giacalone, Nino Dispensa, Marco Vella, Alchiede Simonato
The aim of our work was to evaluate the long-term changes in symptoms (median 42 months) and to analyze data for any negative predictive factors for the application of the procedure, in patients who underwent to urethroplasty with dorsal buccal mucosa graft. During the period from 2010 to 2015 27 patients were examined. Than they underwent urethroplasty using dorsal buccal mucosa graft (graft of 4 x 2.5 cm). The evaluation of symptoms has been addressed through the application of the IPSS Quality of Life Questionnaire (International Prostatic Symptoms Score) and the evaluation of urinary flow has been carried out by a comparative analysis between the pre- and post-operative uroflowmetry...
March 31, 2017: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28403494/-macrohaematuria-in-children
#7
Franziska E Müller-Semaan, Stefan C Müller
Urethritis posterior is a possible cause of asymptomatic haematuria in prepubescent boys. It is a benign lesion of the posterior urethra and its cardinal symptoms are blood spots in the underwear without any laboratory or radiologic findings. Urethrocystoscopy is the only way to confirm the diagnosis, but has been subject to criticism as it is associated with a high risk of strictures. It is advisable to adopt a "wait and see" strategy because urethritis posterior usually heals spontaneously over time. This condition is most likely caused by detrusor-sphincter dyssynergia, since behavioural intervention with biofeedback therapy offers good treatment results...
February 2017: Aktuelle Urologie
https://www.readbyqxmd.com/read/28360950/management-of-pelvic-fracture-associated-urethral-injuries-a-survey-of-canadian-urologists
#8
Nathan Colin Wong, Christopher B Allard, Shawn Dason, Patricia Farrugia, Mohit Bhandari, Timothy O Davies
INTRODUCTION: The management of pelvic fracture-associated urethral injuries (PFUI) is not standardized and optimal management is controversial. We surveyed Canadian urologists about their experiences and opinions regarding optimal management of PFUI. METHODS: Canadian urologists were surveyed via an anonymous, bilingual, web-based, 12-item questionnaire. A total of 735 Canadian urologists were invited to participate via email distributed by the Canadian Urological Association...
March 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28359778/one-stage-repair-of-proximal-hypospadias-with-severe-chordee-by-in-situ-tubularization-of-the-transverse-preputial-island-flap
#9
Yichen Huang, Hua Xie, Yiqing Lv, Ling Yu, Li Sun, Xiaoxi Li, Yan Chen, Huizhen Sun, Fang Chen
INTRODUCTION: To investigate a modified transverse preputial island flap repair which is performed in an attempt to reduce the complications following one-stage repair of proximal hypospadias with chordee. METHODS: Briefly, the two ends of the flap were trimmed into V shape and anastomosed with the spatulated urethra proximally and urethral plate distally before tubularization. Then the in situ tubularization of the flap was performed. The procedure was performed in our hospital on 32 patients (mean age = 11 months)...
March 16, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28347354/equipoise-across-the-patient-population-optimising-recruitment-to-a-randomised-controlled-trial
#10
Paul Whybrow, Robert Pickard, Susan Hrisos, Tim Rapley
BACKGROUND: This paper proposes a novel perspective on the value of qualitative research for improving trial design and optimising recruitment. We report findings from a qualitative study set within the OPEN trial, a surgical randomised controlled trial (RCT) comparing two interventions for recurrent bulbar urethral stricture, a common cause of urinary problems in men. METHODS: Interviews were conducted with men meeting trial eligibility criteria (n = 19) to explore reasons for accepting or declining participation and with operating urologists (n = 15) to explore trial acceptability...
March 27, 2017: Trials
https://www.readbyqxmd.com/read/28346770/a-core-outcome-set-for-localised-prostate-cancer-effectiveness-trials
#11
Steven MacLennan, Paula R Williamson, Hanneke Bekema, Marion Campbell, Craig Ramsay, James N'Dow, Sara MacLennan, Luke Vale, Philipp Dahm, Nicolas Mottet, Thomas Lam, Paul Abel, Hashim U Ahmed, Gary Akehurst, Robert Almquist, Karl Beck, David Budd, Steven Canfield, James Catto, Philip Cornford, William Cross, Alexander Ewen, Judith Grant, Rakesh Heer, David Hurst, Rob Jones, Roger Kockelbergh, Andrew Mackie, Graham MacDonald, Alan McNeill, Malcolm Mason, Sam McClinton, Duncan McLaren, Hugh Mostafid, Ian Pearce, Linda Pennet, Justine Royle, Hans Schreuder, Grant D Stewart, Henk van der Poel, Kevin Wardlaw, Thomas Wiegel
OBJECTIVE: To develop a core outcome set (COS) applicable for effectiveness trials of all interventions for localised prostate cancer. BACKGROUND: Many treatments exist for localised prostate cancer, although it is unclear which offers the optimal therapeutic ratio. This is confounded by inconsistencies in the selection, definition, measurement and reporting of outcomes in clinical trials. SUBJECTS AND METHODS: A list of 79 outcomes was derived from a systematic review of published localised prostate cancer effectiveness studies and semi-structured interviews with 15 prostate cancer patients...
March 27, 2017: BJU International
https://www.readbyqxmd.com/read/28346712/comparison-of-three-methods-to-analyze-detrusor-contraction-during-micturition-in-men-over-50-years-of-age
#12
Celine Ten Donkelaar S, Peter Rosier, Laetitia de Kort
AIMS: To grade detrusor voiding contraction three parameters are used: the Schäfer pressure-flow nomogram (LinPURR), the bladder contractility index (BCI) and the maximum Watt factor (Wmax ). Because these methods to quantify detrusor contraction and/or to diagnose detrusor underactivity (DU) have not yet been mutually compared, this study compares these three methods of grading detrusor contraction. MATERIALS AND METHODS: Evaluated were 1420 urodynamic pressure-flow studies from 1222 men (aged >50 years) with lower urinary tract symptoms (LUTS)...
March 27, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28341425/proximal-hypospadias-repair-with-bladder-mucosal-graft-our-10-years-experience
#13
Michele Lanciotti, Marta Betti, Antonio Elia, Luca Landi, Maria Taverna, Chiara Cini, Lorenzo Masieri
INTRODUCTION AND OBJECTIVE: A great variety of different surgical techniques has been described for proximal hypospadias repair and an ideal tissue has not been determined yet. We present our 10 years of surgical experience using a bladder mucosal graft for urethroplasty. STUDY DESIGN: Bladder mucosal graft urethroplasty was performed between 2005 and 2015 in 50 patients with severe proximal hypospadias. The mean age of patients was 45.1 months (range 24-164 months)...
February 17, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28341232/lower-urinary-tract-symptoms-and-sexual-functions-after-endorectal-pull-through-for-hirschsprung-disease-controlled-long-term-outcomes
#14
Malla Neuvonen, Kristiina Kyrklund, Seppo Taskinen, Antti Koivusalo, Risto J Rintala, Mikko P Pakarinen
BACKGROUND/PURPOSE: To define the prevalence of lower urinary tract symptoms (LUTS) and outcomes for sexual function after endorectal pull-through (EPT) for Hirschsprung disease (HD) compared to controls. To date, similar controlled studies are lacking. METHODS: Patients aged ≥4years (n=123) operated on for HD at our center between 1987 and 2011 were invited to answer questionnaires on LUTS and sexual function (aged ≥16years). Patients with an intellectual disability and patients with a definitive endostomy were excluded...
March 6, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28337443/urethral-reconstruction-using-mesothelial-cell-seeded-autogenous-granulation-tissue-tube-an-experimental-study-in-male-rabbits
#15
Shiwei Jiang, Zhonghua Xu, Yuanyuan Zhao, Lei Yan, Zunlin Zhou, Gangli Gu
Objective. This study was to evaluate the utility of the compound graft for tubularized urethroplasty by seeding mesothelial cells onto autogenous granulation tissue. Methods. Silastic tubes were implanted subcutaneously in 18 male rabbits, of which nine underwent omentum biopsies simultaneously for in vitro expansion of mesothelial cells. The granulation tissue covering the tubes was harvested 2 weeks after operation. Mesothelial cells were seeded onto and cocultured with the tissue for 7 days. A pendulous urethral segment of 1...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28329749/urethral-reconstruction-using-everted-saphenous-vein-graft-in-a-rabbit-model-one-year-outcomes
#16
Yujie Xu, Zhou Shen, Gang Liu, Bing Liu, Xiaoliang Hua, Yechen Xiang, Chuanjiang Dong, Bing Li
OBJECTIVE: To investigate the efficacy of using everted saphenous vein graft for urethral reconstruction. MATERIALS AND METHODS: Thirty-five adult male rabbits were divided into 7 groups randomly: experimental group A, B, C, D, E, stricture control group and normal control group (n = 5). In experimental groups and the stricture control group, a urethral mucosa defect (1.5 × 0.8 cm) was created in each rabbit. In experimental groups, a 2-cm long saphenous vein graft was harvested and incised longitudinally and urethral reconstruction was carried out using the everted saphenous vein patch...
March 23, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28314701/genitourinary-involvement-and-management-in-children-with-stevens-johnson-syndrome-and-toxic-epidermal-necrolysis
#17
J P Van Batavia, D I Chu, C J Long, M Jen, D A Canning, D A Weiss
BACKGROUND: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are devastating hypersensitivity disorders that cause epidermal cell death and can affect all epidermal surfaces, including the urethra, vagina, labial and scrotal skin. Despite the well-described ocular and orofacial manifestations of SJS/TEN, there is a paucity of reports on the genitourinary (GU) symptoms and their management. Specifically, consulting services often ask the pediatric urology team if it is safe to place a urethral catheter, but there is no data in the literature to help guide management...
February 27, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28286073/intermediate-term-outcomes-and-complications-of-long-segment-urethroplasty-with-lingual-mucosa-grafts
#18
Yue-Min Xu, Chao Li, Hong Xie, Ying-Long Sa, Qiang Fu, Deng-Long Wu, Jiong Zhang, Chao Feng, Chong-Rui Jin, Lu-Jie Song, Hong-Bin Li, Ying Liu
PURPOSE: We evaluated the outcomes and donor site complications of male patients with complex urethral strictures (CUS) that underwent urethroplasty by using with long-strip oral mucosal grafts (OMGs). The study analyzed whether lingual mucosa graft (LMG) is a good substitute for repairing long segment urethral strictures. MATERIALS AND METHODS: This was a retrospective study of 81 male patients with CUS that underwent OMGs urethroplasty. Patients with long segment anterior urethral strictures(≥8 cm)that were considered for long-strip LMG urethroplasty were included in the study...
March 9, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28285314/the-staged-urethroplasty-with-vascularised-scrotal-flap-and-buccal-mucosa-graft-after-failed-hypospadias-surgery-a-reliable-technique-with-a-novel-tool
#19
Abhishek Pandey, Anna-Maria Barta-Kelemen, Michael Borisenkov, Hansjörg Keller
Background/Aims/Objectives: To report the outcome of staged urethroplasty with buccal mucosa and vascularised scrotal flap after failed hypospadias surgery. METHODS: n = 35. INCLUSION CRITERIA: destroyed urethral plate, deficient local skin, fistula and penile deviation. Five out of 35 patients also had a secondary proximal stricture. Stage 1: excision of scarred tissue and fistulae, correction of the penile deviation through dorsal plication and the ventral placement and quilting of buccal graft...
March 11, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28279224/urethral-reconstruction-with-autologous-urine-derived-stem-cells-seeded-in-three-dimensional-porous-small-intestinal-submucosa-in-a-rabbit-model
#20
Yang Liu, Wenjun Ma, Bo Liu, Yangcai Wang, Jiaqiang Chu, Geng Xiong, Lianju Shen, Chunlan Long, Tao Lin, Dawei He, Denis Butnaru, Lyundup Alexey, Yuanyuan Zhang, Deying Zhang, Guanghui Wei
BACKGROUND: Urethral reconstruction is one of the great surgical challenges for urologists. A cell-based tissue-engineered urethra may be an alternative for patients who have complicated long strictures and need urethral reconstruction. Here, we demonstrated the feasibility of using autologous urine-derived stem cells (USCs) seeded on small intestinal submucosa (SIS) to repair a urethral defect in a rabbit model. METHODS: Autologous USCs were obtained and characterized, and their capacity to differentiate into urothelial cells (UCs) and smooth muscle cells (SMCs) was tested...
March 9, 2017: Stem Cell Research & Therapy
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