Saeedeh Mahmoodifar, Dhiraj J Pangal, Josh Neman, Gabriel Zada, Jeremy Mason, Bodour Salhia, Tehila Kaisman-Elbaz, Selcuk Peker, Yavuz Samanci, Andréanne Hamel, David Mathieu, Manjul Tripathi, Jason Sheehan, Stylianos Pikis, Georgios Mantziaris, Paul K Newton
OBJECTIVE: Brain metastases (BM) are associated with poor prognosis and increased mortality rates, making them a significant clinical challenge. Studying BMs can aid in improving early detection and monitoring. Systematic comparisons of anatomical distributions of BM from different primary cancers, however, remain largely unavailable. METHODS: To test the hypothesis that anatomical BM distributions differ based on primary cancer type, we analyze the spatial coordinates of BMs for five different primary cancer types along principal component (PC) axes...
April 2, 2024: Journal of Neuro-oncology