keyword
MENU ▼
Read by QxMD icon Read
search

Fibers emerging

keyword
https://www.readbyqxmd.com/read/29163648/fiber-gene-based-molecular-and-biological-characterization-of-hydropericardium-hepatitis-syndrome-associated-avian-adenoviruses
#1
S Yasmeen, N Siddique, M Athar Abbas, A Ali, S Rafique, F Rashid, A U Shah, F Mehmood, I Begum, T Javaid, S M H Jaffery, R Ali, Kh Naeem
This study was designed to perform biological and molecular characterization of avian adenoviruses (AAVs) recovered from suspected cases of hydropericardium-hepatitis syndrome (HHS) in commercial poultry. Initially the samples were screened by Agar Gel Precipitation Test (AGPT) for the presence of AAVs followed by its confirmation and typing through polymerase chain reaction (PCR) focusing on already reported serotypes AAV-4, AAV-8 and AAV-10 elsewhere. These PCR-positive samples were further subjected to amplification of fiber gene, followed by conducting restriction fragment length polymorphism (RFLP) using restriction enzyme Alu...
2017: Iranian journal of veterinary research
https://www.readbyqxmd.com/read/29148704/electrospun-poly-3-hydroxybutyrate-co-4-hydroxybutyrate-graphene-oxide-scaffold-enhanced-properties-and-promoted-in-vivo-bone-repair-in-rats
#2
Tengfei Zhou, Guo Li, Shiyu Lin, Taoran Tian, Quanquan Ma, Qi Zhang, Sirong Shi, Changyue Xue, Wenjuan Ma, Xiaoxiao Cai, Yunfeng Lin
Bone tissue engineering emerges as an advantageous technique to achieve tissue regeneration. Scaffolds for it must present excellent biomechanical properties where bare polymers poorly perform. Development for new biomaterials with high osteogenic capacity is urgently pursued. In this study, an electrospun poly(3-hydroxybutyrate-co-4-hydroxybutyrate/graphene oxide (P34HB/GO) nanofibrous scaffold is successfully fabricated and characterized. The effects of GO amount on scaffold morphology, biomechanical properties, and cellular behaviors are investigated...
November 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29144523/protein-templated-gold-nanoparticle-synthesis-protein-organization-controlled-gold-sequestration-and-unexpected-reaction-products
#3
Cassidy Hart, Nouf Abuladel, Madeleine Bee, Megan C Kreider, Alexander C CVitan, Moira M Esson, Andrew Farag, Trisha Ibeh, Eleni N Kalivas, Daniel-Mario Larco, Andrew Walker Long, Loukas Lymperopoulos, Zachary Mendel, Nancy Miles, Carly M Zareba, James C Schwabacher, Helen Slucher, Javier Vinals, John M Heddleston, Wenyue Li, Douglas M Fox, Matthew R Hartings
Emerging applications that exploit the properties of nanoparticles for biotechnology require that the nanoparticles be biocompatible or support biological recognition. These types of particles can be produced through syntheses that involve biologically relevant molecules (proteins or natural extracts, for example). Many of the protocols that rely on these molecules are performed without a clear understanding of the mechanism by which the materials are produced. We have investigated a previously described reaction in which gold nanoparticles are produced from the reaction of chloroauric acid and proteins in solution...
November 16, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29142274/super-achromatic-monolithic-microprobe-for-ultrahigh-resolution-endoscopic-optical-coherence-tomography-at-800%C3%A2-nm
#4
Wu Yuan, Robert Brown, Wayne Mitzner, Lonny Yarmus, Xingde Li
Endoscopic optical coherence tomography (OCT) has emerged as a valuable tool for advancing our understanding of the histomorphology of various internal luminal organs and studying the pathogenesis of relevant diseases. To date, this technology affords limited resolving power for discerning subtle pathological changes associated with early diseases. In addition, it remains challenging to access small luminal organs or pass through narrow luminal sections without potentially causing trauma to tissue with a traditional OCT endoscope of a 1-1...
November 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/29140463/anatomic-investigation-of-the-trajectory-for-stereotactic-laser-amygdalohippocampectomy
#5
Vanessa M Holanda, Abuzer Gungor, Serhat Baydin, Erik H Middlebrooks, Shabbar F Danish
BACKGROUND: Magnetic resonance imaging-guided laser interstitial thermal therapy (LITT) has emerged as a promising treatment for mesial temporal lobe epilepsy. Surgeons must understand the relevant anatomy that is traversed by the catheter and affected by ablation. OBJECTIVE: To study the anatomic structures crossed by the LITT catheter until it reaches the amygdala. METHODS: Three human cadaveric heads were implanted with catheters using a frameless stereotactic technique...
November 11, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29133062/anatomical-and-physiological-basis-of-continuous-spike-wave-of-sleep-syndrome-after-early-thalamic-lesions
#6
Alberto Leal, Eulália Calado, José P Vieira, Carla Mendonça, José C Ferreira, Hugo Ferreira, Daniel Carvalho, Fátima Furtado, Roseli Gomes, José P Monteiro
OBJECTIVE: Early neonatal thalamic lesions account for about 14% of continuous spike-wave of sleep (CSWS) syndrome, representing the most common etiology in this epileptic encephalopathy in children, and promise useful insights into the pathophysiology of the disease. METHODS: We describe nine patients with unilateral neonatal thalamic lesions which progressed to CSWS. Longitudinal whole-night and high-density electroencephalograms (EEGs) were performed, as well as detailed imaging and clinical evaluation...
November 10, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29128709/integrating-experiment-theory-and-simulation-to-determine-the-structure-and-dynamics-of-mammalian-chromosomes
#7
REVIEW
G Tiana, L Giorgetti
Eukaryotic chromosomes are complex polymers, which largely exceed in size most biomolecules that are usually modelled in computational studies and whose molecular interactions are to a large extent unknown. Since the folding of the chromatin fiber in the cell nucleus is tightly linked to biological function and gene expression in particular, characterizing the conformational and dynamical properties of chromosomes has become crucial in order to better understand how genes are regulated. In parallel with the development of experimental techniques allowing to measure physical contacts within chromosomes inside the cell nucleus, a large variety of physical models to study the structure and mechanisms of chromosome folding have recently emerged...
November 8, 2017: Current Opinion in Structural Biology
https://www.readbyqxmd.com/read/29126955/white-matter-changes-correlates-of-peripheral-neuroinflammation-in-patients-with-parkinson-s-disease
#8
Maryam Haghashomar, Farzaneh Rahmani, Mohammad Hadi Aarabi, Shima Shahjouei, Soheila Sobhnai, Maryam Rahmani
Neuroinflammatory pathology has long been identified to contribute to the pathology of Parkinson disease. Early microstructural changes in white matter tracts might give a clue for earlier detection of PD. We investigated through diffusion MRI connectometry the structural correlates of white matter tracts of 81 patients with PD with whole blood neutrophil to lymphocyte ratio (NLR), controlling for age and sex. Diffusion data were reconstructed in the MNI space using q-space diffeomorphic reconstruction to obtain the spin distribution function...
November 7, 2017: Neuroscience
https://www.readbyqxmd.com/read/29121751/prognostic-implications-of-global-myocardial-mechanics-in-hypertrophic-cardiomyopathy-by-cardiovascular-magnetic-resonance-feature-tracking-relations-to-left-ventricular-hypertrophy-and-fibrosis
#9
Rocio Hinojar, Covadonga Fernández-Golfín, Ariana González-Gómez, Luis Miguel Rincón, Maria Plaza-Martin, Eduardo Casas, Ana García-Martín, Mª Angeles Fernandez-Mendez, Amparo Esteban, Jose Julio Jimenez Nacher, Jose Luis Zamorano
BACKGROUND: Interstitial fibrosis, myocardial fiber disarray and non-uniform shortening are common histological features of hypertrophic cardiomyopathy (HCM). The degree of LV hypertrophy and fibrosis are postulated to contribute to the impairment of myocardial shortening. Cardiovascular magnetic resonance myocardial (CMR) feature tracking (CMR-FT) has emerged as a robust method that provides quantitative measurements of myocardial deformation. Our aim was first to evaluate LV strain parameters in HCM by CMR-FT and their dependence on both functional parameters and late gadolinium enhancement (LGE); and secondly we sought to determine their association with major cardiovascular outcomes...
December 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29119152/quantitative-characterisation-of-conductive-fibers-by-capacitive-coupling
#10
Andres Ruland, Rouhollah Jalili, Attila J Mozer, Gordon G Wallace
This work presents a study on a capacitively coupled contactless conductivity detector (C4D) for micron-sized fibers. Following a previous report on the qualitative application of C4D for fibers, the present study provides a thorough analysis of the signal response to fiber conductivity. Using reduced graphene oxide (RGO) fibers, the detector response as a function of fiber length, cross-sectional area and resistance has been investigated. To study the effect of insulating coatings, Parylene-coated RGO fibers were also investigated...
November 9, 2017: Analyst
https://www.readbyqxmd.com/read/29114842/the-3d-retinal-capillary-circulation-in-pigs-reveals-a-predominant-serial-organization
#11
Stéphane Fouquet, Ophélie Vacca, Florian Sennlaub, Michel Paques
Purpose: To establish a model of the retinal capillary circulation in pigs, which in many aspects is close to the human retina. Methods: Using high density confocal microscopy image stacks of immunolabeled porcine retinal whole mounts, microvessels close to the optic nerve head were traced in three dimensions. The direction of flow of individual capillaries was deduced from their arteriolar and/or venous connections. Results: From major arteries, second-order arteries traversed the nerve fiber layer and resolved exclusively into the superficial vascular plexus (SVP), which dichotomized the blood flow between radial peripapillary capillaries (RPCs) on one side and the intermediate (IVP) and deep vascular plexus (DVP) on the other...
November 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29114043/subplate-neurons-are-the-first-cortical-neurons-to-respond-to-sensory-stimuli
#12
Jessica M Wess, Amal Isaiah, Paul V Watkins, Patrick O Kanold
In utero experience, such as maternal speech in humans, can shape later perception, although the underlying cortical substrate is unknown. In adult mammals, ascending thalamocortical projections target layer 4, and the onset of sensory responses in the cortex is thought to be dependent on the onset of thalamocortical transmission to layer 4 as well as the ear and eye opening. In developing animals, thalamic fibers do not target layer 4 but instead target subplate neurons deep in the developing white matter...
November 7, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29101657/prebiotics-and-bone
#13
Corrie M Whisner, Connie M Weaver
Recent advancements in food science have resulted in the extraction and synthesis of novel dietary fibers or prebiotics. Subsequently, great interest has emerged in developing strategies to improve metabolic conditions like osteoporosis by modulating the intestinal microbiome with fiber. Prebiotics have been shown to increase calcium absorption in the lower gut of both animals and humans as well as improve measures of bone mineral density and strength in rodent models. Fewer data are available in humans, but data from growing children and postmenopausal women suggest that prebiotics have both short- and long-term effects that beneficially affect bone turnover and mineral accretion in the skeleton...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29101217/epigenetic-histone-deacetylation-inhibition-prevents-the-development-and-persistence-of-temporal-lobe-epilepsy
#14
Sandesh D Reddy, Bryan C Clossen, Doodipala Samba Reddy
Epilepsy is a chronic brain disease characterized by repeated unprovoked seizures. Currently, no drug therapy exists for curing epilepsy or disease-modification in people at risk. Despite several emerging mechanisms, there have been few studies of epigenetic signaling in epileptogenesis, the process whereby a normal brain becomes progressively epileptic because of precipitating factors. Here, we report a novel role of histone deacetylation as critical epigenetic mechanism in epileptogenesis. Experiments were conducted using the histone deacetylase (HDAC) inhibitor sodium butyrate in the hippocampus kindling model of temporal lobe epilepsy (TLE), a classic model heavily used to approve drugs for treatment of epilepsy...
November 3, 2017: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/29094460/hydrogel-fiber-conductive-scaffold-for-bone-tissue-engineering
#15
Sajedeh Khorshidi, Akbar Karkhaneh
Hydrogel/fiber composites have emerged as compelling scaffolds for regeneration purposes. Any bio-related modification or feature may endow more regenerative functionality to these composites. In the present study, a hydrogel/fiber scaffold possessing electrical conductivity in both phases, hydrogel and fiber, has been prepared and evaluated. Fiber component possessed electrical conductivity due to the presence of polyaniline (PANi) and hydrogel fraction thanks to the presence of graphene nanoparticles. PANi based fibers were processed via electrospinning and transformed into a three-dimensional structure through ultrasonication...
November 1, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29079996/prebiotics-bone-and-mineral-metabolism
#16
REVIEW
Corrie M Whisner, Luisa F Castillo
Increasing interest in functional foods has driven discovery in the area of bioactive compounds. Prebiotics are non-digestible carbohydrate compounds that, when consumed, elicit health benefits and aid in the prevention and treatment of chronic diseases. While prebiotics have been shown to improve a number of chronic, inflammatory conditions, growing evidence exists for prebiotic effects on calcium metabolism and bone health. These novel dietary fibers have been shown to increase calcium absorption in the lower intestines of both preclinical and human models...
October 27, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/29079337/oseltamivir-zanamivir-combination-therapy-suppresses-drug-resistant-h1n1-influenza-a-viruses-in-the-hollow-fiber-infection-model-hfim-system
#17
Camilly P Pires de Mello, George L Drusano, Jonathan R Adams, Matthew Shudt, Robert Kulawy, Ashley N Brown
Drug-resistant influenza is a significant threat to global public health. Until new antiviral agents with novel mechanisms of action become available, there is a pressing need for alternative treatment strategies with available influenza antivirals. Our aims were to evaluate the antiviral activity of two neuraminidase inhibitors (oseltamivir and zanamivir) as combination therapy against H1N1 influenza A viruses, as these agents bind to the neuraminidase active site differently: oseltamivir requires a conformational change for binding whereas zanamivir does not...
January 1, 2018: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29077618/urinary-oxygenation-as-a-surrogate-measure-of-medullary-oxygenation-during-angiotensin-ii-therapy-in-septic-acute-kidney-injury
#18
Yugeesh R Lankadeva, Junko Kosaka, Roger G Evans, Rinaldo Bellomo, Clive N May
OBJECTIVES: Angiotensin II is an emerging therapy for septic acute kidney injury, but it is unknown if its vasoconstrictor action induces renal hypoxia. We therefore examined the effects of angiotensin II on intrarenal PO2 in ovine sepsis. We also assessed the validity of urinary PO2 as a surrogate measure of medullary PO2. DESIGN: Interventional study. SETTING: Research Institute. SUBJECTS: Sixteen adult Merino ewes (n = 8/group)...
October 26, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/29067384/wide-spectral-dynamic-range-skin-compatible-phototransistors-enabled-by-floated-heterojunction-structures-with-surface-functionalized-swcnts-and-amorphous-oxide-semiconductors
#19
Insik Hwang, Jaehyun Kim, Minkyung Lee, Min-Wook Lee, Hee-Joong Kim, Hyuck-In Kwon, Do Kyung Hwang, Myunggil Kim, Haeyoung Yoon, Yong-Hoon Kim, Sung Kyu Park
Purified semiconducting single-walled carbon nanotubes (sc-SWCNTs) have been researched for optoelectronic applications due to their high absorption coefficient from the visible to even the near-infrared (NIR) region. Nevertheless, the insufficient electrical characteristics and incompatibility with conventional CMOS processing have limited their wide utilization in this emerging field. Here, we demonstrate highly detective and wide spectral/dynamic range phototransistors incorporating floated heterojunction active layers which are composed of low-temperature sol-gel processed n-type amorphous indium gallium zinc oxide (a-IGZO) stacked with a purified p-type sc-SWCNT layer...
November 9, 2017: Nanoscale
https://www.readbyqxmd.com/read/29057711/the-effects-of-childhood-maltreatment-on-brain-structure-in-adults-with-eating-disorders
#20
Alessio Maria Monteleone, Palmiero Monteleone, Fabrizio Esposito, Anna Prinster, Valeria Ruzzi, Antonietta Canna, Marco Aiello, Francesco Di Salle, Mario Maj
OBJECTIVES: Childhood maltreatment is a non specific risk factor for eating disorders (EDs). However, no study assessed so far the impact of childhood maltreatment on brain structure of adults with EDs. Therefore, we investigated brain areas volumes and fiber tracts integrity of childhood maltreated (Mal) and non-maltreated (noMal) patients with EDs. METHODS: Thirty-six ED women and 16 healthy women underwent a MRI scanning including acquisition of a diffusion tensor imaging (DTI) sequence and a high resolution T1-weighted scan...
October 23, 2017: World Journal of Biological Psychiatry
keyword
keyword
87646
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"