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https://www.readbyqxmd.com/read/29457936/prevalence-structure-and-distribution-of-novel-parasite-cysts-containing-dracunculus-species-in-river-otters-lontra-canadensis-from-arkansas
#1
Renn Tumlison, Allison Surf
Adult female Guinea worms (Dracunculus spp.) usually are reported to occur singly in the extremities of their hosts, from which they deliver their larvae through fistulae in the host's skin into the water. We visually examined for presence of worms in the fascia of the limbs of skinned carcasses of 184 river otters (Lontra canadensis) harvested in Arkansas, and report observations of cysts on wrists and ankles found on 12 otters. Cysts averaged 15.6 X 24.6 mm in size, were round to oval, and contained masses of up to 19 adult female Dracunculus sp...
February 19, 2018: Journal of Parasitology
https://www.readbyqxmd.com/read/29456420/timely-news-for-the-multidisciplinary-care-team
#2
Max Bingham
Welcome to Diabetes Spectrum 's first installment of Diabetes is Primary, a round-up of the latest diabetes developments for health care providers. In this issue, we take a look at radical weight loss for diabetes remission, Hong Kong's diabetes risk assessment and management program, personalized A1C targets, and diabetes diagnoses. The American Diabetes Association (ADA) and European Association for the Study of Diabetes (EASD) panel gives its verdict on continuous glucose monitoring (CGM) devices, and we learn how Medicare will soon pay for a diabetes prevention program...
February 2018: Diabetes Spectrum: a Publication of the American Diabetes Association
https://www.readbyqxmd.com/read/29454858/expression-of-heat-shock-protein-70-and-cell-death-kinetics-after-different-thermal-impacts-on-cultured-retinal-pigment-epithelial-cells
#3
Katharina Kern, Carla-Lotta Mertineit, Ralf Brinkmann, Yoko Miura
Recent technologies are broadening the possibility to treat the retinal pigment epithelium (RPE) with different thermal impacts, from sublethal to lethal ranges. Thus temperature-dependent subcellular molecular responses need to be elucidated in more detail. In this study, RPE cell viability and expression of heat shock protein 70 (Hsp70) were investigated after thermal irradiation with different temperature increase using an in-vitro model. Primary porcine RPE cell cultures were irradiated with different laser power of a thulium laser (λ = 1940 nm, beam-diameter 30 mm) for 10 s, such that the maximal temperatures at the center of the culture dish (Tmax ) reach 40, 44, 47, 51 or 59 °C after 10s' irradiation...
February 15, 2018: Experimental Eye Research
https://www.readbyqxmd.com/read/29453648/supplemental-diagnosis-of-gyrodactylus-fairporti-van-cleave-1921-monogenea-from-1-month-old-black-bullhead-ameiurus-melas-in-riverside-pools-in-wisconsin
#4
Eric Leis, Russell Easy, David Cone
Samples of Gyrodactylus fairporti Van Cleave, 1921 from young-of-the-year black bullhead (Ameiurus melas) stranded in riverside pools of the Black River (La Crosse County,) WI, USA, are used to supplement the species diagnosis, including new details on the marginal hook sickles, the male copulatory organ (MCO), and 18S rRNA gene sequence data. The anchors of G. fairporti are relatively long and thin, 58.2 ± 1.2 μm in length; roots 15.5 ± 1.0 μm; shaft 38.1 ± 1.5 μm; point 31.3 ± 1.5 μm. The ventral bar is 19...
February 17, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29453594/time-to-first-event-versus-recurrent-event-analysis-points-to-consider-for-selecting-a-meaningful-analysis-strategy-in-clinical-trials-with-composite-endpoints
#5
Geraldine Rauch, Meinhard Kieser, Harald Binder, Antoni Bayes-Genis, Antje Jahn-Eimermacher
BACKGROUND: Composite endpoints combining several event types of clinical interest often define the primary efficacy outcome in cardiologic trials. They are commonly evaluated as time-to-first-event, thereby following the recommendations of regulatory agencies. However, to assess the patient's full disease burden and to identify preventive factors or interventions, subsequent events following the first one should be considered as well. This is especially important in cohort studies and RCTs with a long follow-up leading to a higher number of observed events per patients...
February 16, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29450216/a-multidisciplinary-delphi-consensus-based-checklist-to-define-clinical-documentation-tools-for-both-routine-and-research-purposes
#6
Cecilia Veraar, Paul Hasler, Michael Schirmer
Background: To the best of our knowledge, a strategic approach to define the contents of structured clinical documentation tools for both clinical routine patient care and research purposes has not been reported so far, although electronic health record will become more and more structured and detailed in the future. Objective: To achieve an interdisciplinary consensus on a checklist to be considered for the preparation of disease- and situation-specific clinical documentation tools...
January 2018: Health Services Research and Managerial Epidemiology
https://www.readbyqxmd.com/read/29448017/fetal-bovine-serum-free-cryopreservation-methods-for-clinical-banking-of-human-adipose-derived-stem-cells
#7
Seah Park, Dong Ryul Lee, Ji Sun Nam, Chul Woo Ahn, Haekwon Kim
The use of fetal bovine serum (FBS) as a cryopreservation supplement is not suitable for the banking of mesenchymal stem cells (MSCs) due to the risk of transmission of disease as well as xenogeneic immune reactions in the transplanted host. Here, we investigated if human serum albumin (HSA), human serum (HS), or knockout serum replacement (KSR) can replace FBS for the cryopreservation of MSCs. In addition, we examined the characteristics of MSCs after multiple rounds of cryopreservation. Human adipose-derived stem cells (ASCs) cryopreserved with three FBS replacements, 9% HSA, 90% HS, or 90% KSR, in combination with 10% dimethyl sulfoxide (Me 2 SO) maintained stem cell properties including growth, immunophenotypes, gene expression patterns, and the potential to differentiate into adipogenic, osteogenic, and chondrogenic lineages, similar to ASCs frozen with FBS...
February 12, 2018: Cryobiology
https://www.readbyqxmd.com/read/29447297/development-of-a-decision-aid-for-cardiopulmonary-resuscitation-and-invasive-mechanical-ventilation-in-the-intensive-care-unit-employing-user-centered-design-and-a-wiki-platform-for-rapid-prototyping
#8
Ariane Plaisance, Holly O Witteman, Annie LeBlanc, Jennifer Kryworuchko, Daren Keith Heyland, Mark H Ebell, Louisa Blair, Diane Tapp, Audrey Dupuis, Carole-Anne Lavoie-Bérard, Carrie Anna McGinn, France Légaré, Patrick Michel Archambault
BACKGROUND: Upon admission to an intensive care unit (ICU), all patients should discuss their goals of care and express their wishes concerning life-sustaining interventions (e.g., cardiopulmonary resuscitation (CPR)). Without such discussions, interventions that prolong life at the cost of decreasing its quality may be used without appropriate guidance from patients. OBJECTIVES: To adapt an existing decision aid about CPR to create a wiki-based decision aid individually adapted to each patient's risk factors; and to document the use of a wiki platform for this purpose...
2018: PloS One
https://www.readbyqxmd.com/read/29443778/a-primitive-neuroectodermal-tumor-in-an-adult-case-report-of-a-unique-location-and-mri-characteristics
#9
Xin He, Zhongping Chen, Yutong Dong, Dan Tong
RATIONALE: Central nervous system primitive neuroectodermal tumors (CNS PNETs) mostly occur in children and present as cerebellar medulloblastoma. A few cases of PNETs occur in the cerebral hemisphere. The presence of a PNET in ventricles is extremely rare. The prognosis of CNS PNET is extremely poor, and the 5-year survival rate does not exceed 35%. In the present study, we describe the first case of a PNET in the ventricles with good prognosis. PATIENT CONCERNS: The case of a 36-year-old man is reported, who presented with a progressively worsening headache for 2 months...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29442853/effect-of-annealing-temperature-on-morphological-and-optical-transition-of-silver-nanoparticles-on-c-plane-sapphire
#10
Puran Pandey, Sundar Kunwar, Mao Sui, Ming-Yu Li, Quanzhen Zhang, Jihoon Lee
As a promising candidate for the improved performance, silver nanoparticles (Ag NPs) have been successfully adapted in various applications such as photovoltaics, light emitting diodes (LEDs), sensors and catalysis by taking the advantage of their controllable plasmonic properties. In this paper, the control on the morphologies and optical properties of Ag NPs on c-plane sapphire (0001) is demonstrated by the systematic control of annealing temperature (between 200 and 950 °C) with 20 and 6 nm thick Ag films through the solid state dewetting...
May 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29442127/situation-analysis-of-rehabilitation-service-to-support-the-national-disability-and-rehabilitation-plan-in-the-democratic-people%C3%A2-s-republic-of-korea
#11
Boya Nugraha, Christoph Gutenbrunner
OBJECTIVE: In 2013, the Democratic People's Republic of Korea (DPRK) signed the United Nations Convention on the Rights of Persons with Disabilities (UN-CRPD). Since the concept of rehabilitation services in the DPRK did not meet international standards, the government, through the Korean Federation for Protection of the Disabled (KFPD) and Munsu Rehabilitation Hospital (MRH), set up a technical consultation with external experts. METHODS: Two rounds of consultations were performed, in August 2016 and March 2017, with available methodology, as used in previous consultation processes, but excluding site visits...
February 14, 2018: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29439238/live-imaging-of-neurogenesis-in-the-adult-mouse-hippocampus
#12
Gregor-Alexander Pilz, Sara Bottes, Marion Betizeau, David J Jörg, Stefano Carta, Benjamin D Simons, Fritjof Helmchen, Sebastian Jessberger
Neural stem and progenitor cells (NSPCs) generate neurons throughout life in the mammalian hippocampus. We used chronic in vivo imaging and followed genetically labeled individual NSPCs and their progeny in the mouse hippocampus for up to 2 months. We show that NSPCs targeted by the endogenous Achaete-scute homolog 1 (Ascl1) promoter undergo limited rounds of symmetric and asymmetric divisions, eliciting a burst of neurogenic activity, after which they are lost. Further, our data reveal unexpected asymmetric divisions of nonradial glia-like NSPCs...
February 9, 2018: Science
https://www.readbyqxmd.com/read/29439189/socioeconomic-inequality-in-recovery-from-poor-physical-and-mental-health-in-mid-life-and-early-old-age-prospective-whitehall-ii-cohort-study
#13
REVIEW
Akihiro Tanaka, Martin J Shipley, Catherine A Welch, Nora E Groce, Michael G Marmot, Mika Kivimaki, Archana Singh-Manoux, Eric J Brunner
BACKGROUND: Few studies have examined the influence of socioeconomic status on recovery from poor physical and mental health. METHODS: Prospective study with four consecutive periods of follow-up (1991-2011) of 7564 civil servants (2228 women) recruited while working in London. Health was measured by the Short-Form 36 questionnaire physical and mental component scores assessed at beginning and end of each of four rounds. Poor health was defined by a score in the lowest 20% of the age-sex-specific distribution...
February 8, 2018: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29432337/improving-patient-safety-culture-a-report-of-a-multifaceted-intervention
#14
Tom Basson, Alfred Montoya, Julia Neily, Lisa Harmon, Bradley V Watts
OBJECTIVE: The aim of the study was to improve the safety culture at a Veterans Administration hospital using evidence-based approaches. METHODS: We implemented a patient safety summit with follow-up actions. We measured safety climate before and after the summit using the Agency for Healthcare Research and Quality (AHRQ) Hospital Survey of Patient Safety Culture with modifications and the Safety Attitudes Questionnaire (SAQ). The summit brought hospital leaders together to discuss patient safety topics and relate them to our hospital...
February 9, 2018: Journal of Patient Safety
https://www.readbyqxmd.com/read/29429159/-retroperitoneal-dedifferentiated-liposarcoma-with-rhabdomyoblastic-differentiation-a-clinicopathological-analysis
#15
L Liu, L H Wang, Y B Ren, X S Rao, S M Yang
Objective: To investigate the clinicopathological features, differential diagnosis, treatment and prognosis of dedifferentiated liposarcoma with rhabdomyoblastic differentiation. Methods: Six cases of retroperitoneal dedifferentiated liposarcoma with rhabdomyoblastic features were collected from December 2014 to August 2017 at Peking University International Hospital. The clinical manifestations, histomorphology, immunophenotype, treatment and follow-up data were analyzed, and relevant literature reviewed. Results: The six patients included two males and four females, with age range of 47 to 66 years (mean 56 years)...
February 8, 2018: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/29428183/re-emergence-of-yaws-after-single-mass-azithromycin-treatment-followed-by-targeted-treatment-a-longitudinal-study
#16
Oriol Mitjà, Charmie Godornes, Wendy Houinei, August Kapa, Raymond Paru, Haina Abel, Camila González-Beiras, Sibauk V Bieb, James Wangi, Alyssa E Barry, Sergi Sanz, Quique Bassat, Sheila A Lukehart
BACKGROUND: Yaws is a substantial cause of chronic disfiguring ulcers in children in at least 14 countries in the tropics. WHO's newly adopted strategy for yaws eradication uses a single round of mass azithromycin treatment followed by targeted treatment programmes, and data from pilot studies have shown a short-term significant reduction of yaws. We assessed the long-term efficacy of the WHO strategy for yaws eradication. METHODS: Between April 15, 2013, and Oct 24, 2016, we did a longitudinal study on a Papua New Guinea island (Lihir; 16 092 population) in which yaws was endemic...
February 7, 2018: Lancet
https://www.readbyqxmd.com/read/29427732/risk-of-oral-and-upper-gastrointestinal-cancers-in-persons-with-positive-results-from-a-fecal-immunochemical-test-in-a-colorectal-cancer-screening-program
#17
Manon van der Vlugt, Esmée J Grobbee, Patrick M Bossuyt, Amanda C R K Bos, Ernst J Kuipers, Iris Lansdorp-Vogelaar, Manon C W Spaander, Evelien Dekker
BACKGROUND & AIMS: European guidelines recommend screening for colorectal cancer (CRC) using the fecal immunochemical test (FIT), with follow-up colonoscopies for individuals with positive test results. However, more than half of participants with positive results from the FIT are not found to have advanced neoplasia in the colonoscopy examination. Fecal occult blood might also come from the upper gastrointestinal (GI) tract, so perhaps we should consider esophagogastroduodenoscopy (EGD), to detect upper GI cancers...
February 7, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29423179/measuring-postnatal-care-contacts-for-mothers-and-newborns-an-analysis-of-data-from-the-mics-and-dhs-surveys
#18
Agbessi Amouzou, Vrinda Mehra, Liliana Carvajal-Aguirre, Shane M Khan, Deborah Sitrin, Lara Me Vaz
Background: The postnatal period represents a vulnerable phase for mothers and newborns where both face increased risk of morbidity and death. WHO recommends postnatal care (PNC) for mothers and newborns to include a first contact within 24 hours following the birth of the child. However, measuring coverage of PNC in household surveys has been variable over time. The two largest household survey programs in low and middle-income countries, the UNICEF-supported Multiple Indicator Cluster Surveys (MICS) and USAID-funded Demographic and Health Surveys (DHS), now include modules that capture these measures...
December 2017: Journal of Global Health
https://www.readbyqxmd.com/read/29419302/all-inkjet-printed-amperometric-multiplexed-biosensors-based-on-nanostructured-conductive-hydrogel-electrodes
#19
Lanlan Li, Lijia Pan, Zhong Ma, Ke Yan, Wen Cheng, Yi Shi, Guihua Yu
Multiplexing, one of the main trends in biosensors, aims to detect several analytes simultaneously by integrating miniature sensors on a chip. However, precisely depositing electrode materials and selective enzymes on distinct microelectrode arrays remains an obstacle to massively produced multiplexed sensors. Here, we report on a "drop-on-demand" inkjet printing process to fabricate multiplexed biosensors based on nanostructured conductive hydrogels, in which the electrode material and several kinds of enzymes were printed on the electrode arrays one by one by employing a multi-nozzle inkjet system...
February 8, 2018: Nano Letters
https://www.readbyqxmd.com/read/29417275/cochlear-implantation-using-the-underwater-technique-long-term-results
#20
Konrad Johannes Stuermer, David Schwarz, Andreas Anagiotos, Ruth Lang-Roth, Karl-Bernd Hüttenbrink, Jan Christoffer Luers
INTRODUCTION: The opening of the round window and the insertion of the electrode array into the scala tympani during cochlear implant surgery can lead to a pressure shock of the delicate inner ear structures. By filling the tympanic cavity with Ringer Solution during these surgical steps (underwater technique), the hydrostatic pressure of the fluid acts as a smooth pressure stabilizer, avoiding a pressure shock of the inner ear structures. The aim of this retrospective study was to present long-term results of this new method of cochlear implantation in underwater technique...
February 7, 2018: European Archives of Oto-rhino-laryngology
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