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https://www.readbyqxmd.com/read/29245071/dual-task-training-in-older-adults-the-effect-of-additional-motor-tasks-on-mobility-performance
#1
Paolo Riccardo Brustio, Emanuela Rabaglietti, Sabrina Formica, Monica Emma Liubicich
OBJECTIVES: Dual-task (DT) performance is common to most activities of daily living and difficulties in DT activities may reduce quality of life in older adults. This study investigated the effect of DT training in a sample of older adults. METHODS: Sixty older adults (mean=74.4±3.1years) participated in the study. Twenty-two older adults were included in the control (CG), 19 in the single-task (ST) training and 19 in DT training group. ST group received balance and walking training twice a week for16 weeks, while DT training group performed the same training with additional motor tasks...
December 10, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29242805/a-case-report-of-primary-synovial-chondromatosis-with-bilateral-genu-valgum
#2
Samir Dwidmuthe, Mohit Sharma
Introduction: Synovial chondromatosis is the rare and benign metaplasia of the synovial membrane resulting in the formation of multiple intra-articular cartilaginous loose bodies. Synovial chondromatosis is known by several other names including articular chondrosis and synovial chondrosis. Case Report: An 18-year-old boy presented with complaints of difficulty in walking with growing deformity with restriction and painful movements of knee joints bilaterally. The patient gives a history of swelling which was initially there about 8 years back and was accompanied by fever...
September 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29242508/variations-in-cochlear-duct-shape-revealed-on-clinical-ct-images-with-an-automatic-tracing-method
#3
Annerie M A van der Jagt, Randy K Kalkman, Jeroen J Briaire, Berit M Verbist, Johan H M Frijns
Cochlear size and morphology vary greatly and may influence the course of a cochlear implant electrode array during insertion and its final intra-cochlear position. Detailed insight into these variations is valuable for characterizing each cochlea and offers the opportunity to study possible correlations with surgical or speech perception outcomes. This study presents an automatic tracing method to assess individual cochlear duct shapes from clinical CT images. On pre-operative CT scans of 479 inner ears the cochlear walls were discriminated by interpolating voxel intensities along radial and perpendicular lines within multiplanar reconstructions at 1 degree intervals from the round window...
December 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29242173/exploring-determinants-of-patient-adherence-to-a-portal-supported-oncology-rehabilitation-program-interview-and-data-log-analyses
#4
Hendrik P Buimer, Monique Tabak, Lex van Velsen, Thea van der Geest, Hermie Hermens
BACKGROUND: Telemedicine applications often do not live up to their expectations and often fail once they have reached the operational phase. OBJECTIVE: The objective of this study was to explore the determinants of patient adherence to a blended care rehabilitation program, which includes a Web portal, from a patient's perspective. METHODS: Patients were enrolled in a 12-week oncology rehabilitation treatment supported by a Web portal that was developed in cooperation with patients and care professionals...
December 14, 2017: JMIR Rehabilitation and Assistive Technologies
https://www.readbyqxmd.com/read/29240786/time-trend-analysis-2009-2016-of-antimicrobial-susceptibility-in-neisseria-gonorrhoeae-isolated-in-italy-following-the-introduction-of-the-combined-antimicrobial-therapy
#5
Paola Stefanelli, Maria Fenicia Vescio, Maria Paola Landini, Ivano Dal Conte, Alberto Matteelli, Antonio Cristaudo, Marina Gaino, Marco Cusini, Anna Maria Barbui, Antonella Mencacci, Rosella De Nittis, Valeria Ghisetti, Elena Stroppiana, Anna Carannante
INTRODUCTION: Neisseria gonorrhoeae (NG) antimicrobial susceptibility trends to azithromycin, cefixime and ceftriaxone were analyzed, from 2009 to 2016, to monitor changing antimicrobial susceptibility concomitant with the change in prescribing practice in 2012 from cefixime, or ceftriaxone, to ceftriaxone plus azithromycin. Patient characteristics predictive to be infected by antibiotic resistant N. gonorrhoeae were estimated. Finally, the protocol for the treatment of gonorrhoea, in comparison with the international guidelines, was also evaluated...
2017: PloS One
https://www.readbyqxmd.com/read/29240667/enabling-factors-for-sustaining-open-defecation-free-communities-in-rural-indonesia-a-cross-sectional-study
#6
Mitsunori Odagiri, Zainal Muhammad, Aidan A Cronin, Michael E Gnilo, Aldy K Mardikanto, Khaerul Umam, Yameha T Asamou
Community Approaches to Total Sanitation (CATS) programmes, like the Sanitasi Total Berbasis Masyarakat (STBM) programme of the Government of Indonesia, have played a significant role in reducing open defecation though still little is known about the sustainability of the outcomes. We assessed the sustainability of verified Open Defecation Free (ODF) villages and explored the association between slippage occurrence and the strength of social norms through a government conducted cross-sectional data collection in rural Indonesia...
December 14, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29240582/the-morphologic-spectrum-of-sertoliform-cystadenoma-of-the-rete-testis-a-series-of-15-cases
#7
Swetha Paluru, Thomas M Ulbright, Mahul Amin, Rodolfo Montironi, Jonathan I Epstein
Sertoliform cystadenoma of the rete testis (SCRT) is rare with only 9 cases reported to date in the literature, none with follow-up. Four large genitourinary pathology consult services were searched. We identified 15 cases of SCRT. Men were 21 to 84 years old (mean, 46 y) and had testicular discomfort or mass. Other findings were seminoma (n=1), spermatocele (n=2), hydrocele (n=1), varicocele (n=1), and scrotal hematoma (n=1). Eight had preoperative serum tumor markers, which were normal. Tumors ranged from 0...
December 7, 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29240305/surgical-anatomy-of-the-round-window-implications-for-cochlear-implantation
#8
REVIEW
Jan Christoffer Luers, Karl-Bernd Hüttenbrink, Dirk Beutner
BACKGROUND: The round window is an important portal for the application of active hearing aids and cochlear implants. The anatomical and topographical knowledge about the round window region is a prerequisite for successful insertion for a cochlear implant electrode. OBJECTIVE OF REVIEW: To sum up current knowledge about the round window anatomy and to give advice to the cochlear implant surgeon for optimal placement of an electrode. TYPE OF REVIEW: Systematic Medline search...
December 14, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29239250/history-off-hand-bunnell-s-no-man-s-land
#9
J Joris Hage
BACKGROUND: To date, it remains unclear what inspired Dr Sterling Bunnell to start using the typical World War I military term no-man's land in hand surgical context, only in 1948. To commemorate that Bunnell passed away 60 years ago on August 20, I report on my quest to clarify this. METHODS: An extensive bibliography of Bunnell was made up by use of the McDowell Series of Plastic Surgery Indexes and cross-checked by use of a PubMed search. Bunnell's round-robin letters were searched for in the Sterling Bunnell Hand Surgery Archives of the California Pacific Medical Center Health Services Library in San Francisco, California...
December 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/29239114/engineering-thermal-stability-and-solvent-tolerance-of-the-soluble-quinoprotein-pede-from-pseudomonas-putida-kt2440-with-a-heterologous-whole-cell-screening-approach
#10
Matthias Wehrmann, Janosch Klebensberger
Due to their ability for direct electron transfer to electrodes, the utilization of rare earth metals as cofactor, and their periplasmic localization, pyrroloquinoline quinone-dependent alcohol dehydrogenases (PQQ-ADHs) represent an interesting class of biocatalysts for various biotechnological applications. For most biocatalysts protein stability is crucial, either to increase the performance of the protein under a given process condition or to maximize robustness of the protein towards mutational manipulations, which are often needed to enhance or introduce a functionality of interest...
December 14, 2017: Microbial Biotechnology
https://www.readbyqxmd.com/read/29236705/automated-segmentation-of-complex-patterns-in-biological-tissues-lessons-from-stingray-tessellated-cartilage
#11
David Knötel, Ronald Seidel, Steffen Prohaska, Mason N Dean, Daniel Baum
INTRODUCTION: Many biological structures show recurring tiling patterns on one structural level or the other. Current image acquisition techniques are able to resolve those tiling patterns to allow quantitative analyses. The resulting image data, however, may contain an enormous number of elements. This renders manual image analysis infeasible, in particular when statistical analysis is to be conducted, requiring a larger number of image data to be analyzed. As a consequence, the analysis process needs to be automated to a large degree...
2017: PloS One
https://www.readbyqxmd.com/read/29236566/genome-profile-in-a-extremely-rare-case-of-pulmonary-sclerosing-pneumocytoma-presenting-with-diffusely-scattered-nodules-in-the-right-lung
#12
Xiangshan Fan, Ling Lin, Jianjun Wang, Yu Wang, Anning Feng, Ling Nie, Hongyan Wu, Fanqing Meng, Haodong Xu
BACKGROUND: Pulmonary sclerosing pneumocytoma (PSP) typically presents solitary and peripheral mass, while only rarely cases display unusual multiple lesions. We reported a extremely rare case of PSP with diffusely-scattered nodules in the right lung. CASE PRESENTATION: Diffusely round-shaped nodular shadows in the right lung were found by CT scan in a 31-year-old Chinese woman. The patient undergone the right pneumnectomy. Grossly, numerous small nodules, up to 2...
December 13, 2017: Cancer Biology & Therapy
https://www.readbyqxmd.com/read/29236021/enhanced-bacterial-quorum-aggregation-on-a-zeolite-capping-layer-for-sustainable-inhibition-of-ammonium-release-from-contaminated-sediment
#13
Jinlan Xu, Haiyang Zhang, Rong Zhao, Fanxing Kong
The main objective of this study was to investigate how signal molecules enhance bacterial quorum aggregation on a zeolite capping layer for sustainable inhibition of ammonium release from contaminated sediment. Sediment remediation experiments were carried out by using nitrifying bacteria (WGX10, WGX18), denitrifying bacteria (HF3, HF7) and two kinds of signal molecules (OHHL, C8-HSL). The results showed that nitrifying bacteria and denitrifying bacteria could significantly aggregate on zeolite after adding 1...
December 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/29234940/st-gallen-consensus-on-safe-implementation-of-transanal-total-mesorectal-excision
#14
Michel Adamina, Nicolas C Buchs, Marta Penna, Roel Hompes
BACKGROUND: The management of rectal cancer has evolved over the years, including the recent rise of Transanal Total Mesorectal Excision (TaTME). TaTME addresses the limitations created by the bony confines of the pelvis, bulky tumours, and fatty mesorectum, particularly for low rectal cancers. However, guidance is required to ensure safe implementation and to avoid the pitfalls and potential major morbidity encountered by the early adopters of TaTME. We report a broad international consensus statement, which provides a basis for optimal clinical practice...
December 12, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29234358/hearing-loss-screening-tool-cobra-score-for-newborns-in-primary-care-setting
#15
Watcharapol Poonual, Niramon Navacharoen, Jaran Kangsanarak, Sirianong Namwongprom, Surasak Saokaew
Purpose: To develop and evaluate a simple screening tool to assess hearing loss in newborns. A derived score was compared with the standard clinical practice tool. Methods: This cohort study was designed to screen the hearing of newborns using transiently evoked otoacoustic emission and auditory brain stem response, and to determine the risk factors associated with hearing loss of newborns in 3 tertiary hospitals in Northern Thailand. Data were prospectively collected from November 1, 2010 to May 31, 2012...
November 2017: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/29233791/incidental-anterior-mediastinal-nodular-lesions-on-chest-ct-in-asymptomatic-subjects
#16
Soon Ho Yoon, Seung Ho Choi, Chang Hyun Kang, Jin Mo Goo
HYPOTHESIS: To investigate the prevalence and characteristics of nodular lesions in the anterior mediastinum that had been incidentally found on screening chest CT in asymptomatic subjects. METHODS: We included 56,358 consecutive participants (mean age, 52.4±10.5 years; male-female, 35,306:21,052) who underwent a baseline low-dose chest CT scan for health checkups from 2006 through 2013. After confirming the presence of anterior mediastinal nodular lesion, their CT findings, confirmatory diagnosis and interval CT scan were reviewed...
December 9, 2017: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/29230245/adaptation-and-molecular-characterization-of-two-malaysian-very-virulent-infectious-bursal-disease-virus-isolates-adapted-in-bgm-70-cell-line
#17
Nafi'u Lawal, Mohd Hair-Bejo, Siti Suri Arshad, Abdul Rahman Omar, Aini Ideris
Two Malaysian very virulent infectious bursal disease virus (vvIBDV) strains UPM0081 and UPM190 (also known as UPMB00/81 and UPM04/190, respectively) isolated from local IBD outbreaks were serially passaged 12 times (EP12) in specific pathogen free (SPF) chicken embryonated eggs (CEE) by chorioallantoic membrane (CAM) route. The EP12 isolate was further adapted and serially propagated in BGM-70 cell line up to 20 passages (P20). Characteristic cytopathic effects (CPEs) were subtly observed at P1 in both isolates 72 hours postinoculation (pi)...
2017: Advances in Virology
https://www.readbyqxmd.com/read/29229960/how-costly-punishment-diversity-and-density-of-connectivity-influence-cooperation-in-a-biological-network
#18
Ivan C Ezeigbo
It has been an old unsolved puzzle to evolutionary theorists on which mechanisms would increase large-scale cooperation in human societies. Thus, how such mechanisms operate in a biological network is still not well understood. This study addresses these questions with empirical evidence from agent-based models designed to understand these network interactions. Repeated Prisoner's Dilemma games were designed to study how costly punishment, diversity, and density of connectivity interact to influence cooperation in a biological network...
December 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29228716/sox2-modulates-motility-and-enhances-progression-of-colorectal-cancer-via-the-rho-rock-signaling-pathway
#19
Junheng Zheng, Lixiao Xu, Yubin Pan, Shuyi Yu, Hongbo Wang, Derek Kennedy, Yan Zhang
Sox2 (Sry-box2) is essential for a variety of stem cells and is also expressed in colorectal cancer (CRC). However, the underlying mechanism by which Sox2 enhances CRC progression remains unclear. In the present study, we show that elevated Sox2 expression is significantly correlated with poor clinical prognosis. CRC is phenotypically heterogeneous, and harbors several subtypes of cancer cells. Elevated Sox2 expression was always detected in rounded-shape cells, which co-located to poorly differentiated regions, the invasive frontier and metastatic lesions...
November 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29226232/connecting-undergraduate-and-postgraduate-medical-education-through-an-elective-epa-based-transitional-year-in-acute-care-an-early-project-report
#20
Gersten Jonker, Reinier G Hoff, Stefan Max, Cor J Kalkman, Olle Ten Cate
Objective: A well-designed final year may ease the transition from medical school to postgraduate training, if it has enough depth to enable the acquisition of early specialty expertise, while keeping enough breadth to support the graduation as all-round physician. Aim of this article is to describe the design of a multidisciplinary dedicated transitional year (DTY) around the theme of recognition and initial treatment of vitally threatened patients. Methods: Undergraduate and postgraduate training directors from the departments of Anaesthesiology, Cardiology, Emergency Medicine, Intensive Care Medicine and Respiratory Medicine at UMC Utrecht and partnering hospitals have collaboratively developed and implemented a curriculum for a final year focusing on three entrustable professional activities (EPAs) in the domain of acute care...
2017: GMS Journal for Medical Education
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