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https://www.readbyqxmd.com/read/29786949/the-qsofa-score-a-simple-and-accurate-predictor-of-outcomes-in-patients-with-glyphosate-herbicide-poisoning
#1
Yongsoo Cho, Byeongjo Chun, Jeongmi Moon
This study aimed to investigate whether the quick Sequential Organ Failure Assessment (qSOFA) score at emergency department (ED) presentation can help improve the risk assessment of glyphosate-surfactant herbicide (GlySH) poisoning complications. A total of 150 patients presenting with acute glyphosate herbicide ingestion were enrolled in this retrospective observational study. The qSOFA scores at presentation, ΔqSOFA (calculated by subtracting the worst qSOFA score from 1 hr after admission from the qSOFA score at presentation), baseline characteristics, clinical courses and outcomes were collected and analysed...
May 22, 2018: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29786585/hygienic-assessment-of-the-effects-of-pesticides-application-on-adult-population-morbidity-with-thyroid-gland-diseases
#2
Anna M Antonenko, Olena P Vavrinevych, Maria M Korshun, Sergiy T Omelchuk
OBJECTIVE: Introduction: It is proved that some groups of fungicides and herbicides are capable of affecting the thyroid gland, provoking its growth, leading to a compensatory change in the activity of the hormones synthesis. Therefore, the presence of their residual amounts in plant may affect the level of thyroid gland pathology. The aim of the work was to analyze the influence of pesticide application on the Ukrainian adult population morbidity with thyroid diseases in the period from 2001 to 2014...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29785001/evaluation-of-weed-control-efficacy-and-crop-safety-of-the-new-hppd-inhibiting-herbicide-qyr301
#3
Hengzhi Wang, Weitang Liu, Kongping Zhao, Hui Yu, Jia Zhang, Jinxin Wang
QYR301, 1,3-Dimethyl-1H-pyrazole-4-carboxylic acid 4-[2-chloro-3-(3,5-dimethyl-pyrazol-1-ylmethyl)-4-methanesulfonyl-benzoyl]-2,5-dimethyl-2H-pyrazol-3-yl ester, is a novel HPPD-inhibiting herbicide and was evaluated to provide a reference for post-emergence (POST) application under greenhouse and field conditions. The crop safety (180 and 360 g active ingredient (a.i.) ha-1 treatments) experiment revealed that wheat, paddy, garlic and corn were the only four crops without injury at both examined herbicide rates...
May 21, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29784424/sensitive-determination-of-seven-triazine-herbicide-in-honey-tomato-and-environmental-water-samples-by-hollow-fiber-based-liquid-liquid-liquid-microextraction-combined-with-sweeping-micellar-electrokinetic-capillary-chromatography
#4
Qing Yang, Beibei Chen, Man He, Bin Hu
A rapid, simple, and effective method has been developed for the determination of seven triazine herbicides (terbutryn, prometryn, ametryn, prometon, propazine, atrazine, simazine) by coupling off-line hollow fiber liquid liquid liquid microextraction (HF-LLLME) with on-line sweeping micellar electrokinetic chromatography (sweeping-MEKC). In HF-LLLME, seven target triazines in hydrophobic form were extracted from the sample solution into decane impregnated in the pores of the hollow fiber, and then back-extracted into 1 mol L-1 H3 PO4 inside the hollow fiber lumen...
August 15, 2018: Talanta
https://www.readbyqxmd.com/read/29778815/photodegradation-of-atrazine-in-the-presence-of-indole-3-acetic-acid-and-natural-montmorillonite-clay-minerals
#5
Lin Zhang, Haoting Tian, Ran Hong, Chao Wang, Yi Wang, Anping Peng, Cheng Gu
Atrazine (2-chloro-4-ethylamino-6-isopropylamino-s-triazine) is a commonly used agricultural herbicide that, as a result, is frequently detected in surface and ground water. In this study, we provide evidence of the photo-oxidation of atrazine under environmentally relevant conditions, specifically, in the presence of natural montmorillonite clay and the ubiquitous phytohormone indole-3-acetic acid (IAA). The reaction is initiated by the generation of hydrated electrons from the photo-ionization of IAA. These electrons react with protons and dissolved oxygen to form hydroxyl radicals, which promote the further degradation of atrazine...
May 17, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29778643/inheritance-of-co-edited-genes-by-crispr-based-targeted-nucleotide-substitutions-in-rice
#6
Zenpei Shimatani, Ushio Fujikura, Hisaki Ishii, Yusuke Matsui, Minoru Suzuki, Yuki Ueke, Ken-Ichiro Taoka, Rie Terada, Keiji Nishida, Akihiko Kondo
The CRISPR/Cas9 system is a revolutionary genome-editing tool for directed gene editing in various organisms. Cas9 variants can be applied as molecular homing devices when combined with various functional effectors such as transcriptional activators or DNA modification enzymes. Target-AID is a synthetic complex of nuclease deficient Cas9 fused to an activation-induced cytidine deaminase (AID) that enables targeted nucleotide substitution (C to T or G to A). We previously demonstrated that the introduction of desired point mutations into target genes by Target-AID confers herbicide tolerance to rice callus...
April 25, 2018: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29778226/imbalanced-nutrient-regimes-increase-prymnesium-parvum-resilience-to-herbicide-exposure
#7
Stacie L Flood, JoAnn M Burkholder
The toxigenic haptophyte Prymnesium parvum is a mixotrophic phytoplankter with an extensive historic record of forming nearly monospecific, high-biomass, ecosystem-disrupting blooms, and it has been responsible for major fish kills in brackish waters and aquaculture facilities in many regions of the world. Little is known about how this species responds to commonly occurring environmental contaminants, or how nutrient (nitrogen, phosphorus) pollution may interact with environmentally relevant pesticide exposures to affect this harmful algal species...
May 2018: Harmful Algae
https://www.readbyqxmd.com/read/29778080/atrazine-xenobiotic-nuclear-receptor-interactions-induce-cardiac-inflammation-and-endoplasmic-reticulum-stress-in-quail-coturnix-coturnix-coturnix
#8
Xue-Nan Li, Yu-Zhu Zuo, Lei Qin, Wei Liu, Yan-Hua Li, Jin-Long Li
Atrazine (ATR) is one of the most extensively used herbicide that eventually leaches into groundwater and surface water from agricultural areas. Exposure to ATR does harm to the health of human and animals, especially the heart. However, ATR exposure caused cardiotoxicity in bird remains unclear. To evaluate ATR-exerted potential cardiotoxicity in heart, quail were exposed with 0, 50, 250, and 500 mg/kg BW/day ATR by gavage treatment for 45 days. Cardiac histopathological alternation was observed in ATR-induced quail...
May 9, 2018: Chemosphere
https://www.readbyqxmd.com/read/29777430/the-artificial-humic-substance-hs1500-does-not-inhibit-photosynthesis-of-the-green-alga-desmodesmus-armatus-in-vivo-but-interacts-with-the-photosynthetic-apparatus-of-isolated-spinach-thylakoids-in-vitro
#9
Matthias Gilbert, Hanno Bährs, Christian E W Steinberg, Christian Wilhelm
Humic substances (HSs) can influence the growth and composition of freshwater phytoplankton assemblage. Since HSs contain many phenolic and quinonic moieties and cause growth reductions in eco-physiological field experiments, HSs are considered photosystem II herbicides. To test this specific mode of action in vivo and in vitro, respectively, we used intact cells of the green alga Desmodesmus armatus, as well as thylakoids isolated from spinach (Spinacia oleracea) as a model system for the green algal chloroplast...
May 18, 2018: Photosynthesis Research
https://www.readbyqxmd.com/read/29777017/old-enzymes-versus-new-herbicides
#10
Tamara L Hendrickson
The introduction of manmade chemicals, including the herbicide atrazine, into the environment has led to the emergence of microorganisms with new biodegradation pathways. Esquirol et al. demonstrate that the AtzE enzyme catalyzes a central step in atrazine degradation and that expression of AtzE requires coexpression of the small protein AtzG. Remarkably, AtzG and AtzE appear to have evolved from GatC and GatA, components of an ancient enzyme involved in indirect tRNA aminoacylation, providing an elegant demonstration of metabolic repurposing...
May 18, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29775953/effect-of-adjuvant-on-pendimethalin-and-dimethenamid-p-behaviour-in-soil
#11
Martin Kočárek, Radka Kodešová, Umrbek Sharipov, Miroslav Jursík
Adjuvants are used to improve pesticides' performance. It is expected that adjuvants should increase sorption and persistence, as well as decrease mobility of pesticides in soils. Impact of the "Grounded" brand adjuvant on the behaviour of two herbicides, pendimethalin and dimethenamid-P, was investigated in a Haplic Chernozem. Both herbicides were tested in a laboratory batch sorption experiment with and without adjuvant. The sorption experiment showed that adjuvant negligibly increased dimethenamid-P sorption (KF  = 2...
April 30, 2018: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29775650/formulants-of-glyphosate-based-herbicides-have-more-deleterious-impact-than-glyphosate-on-tm4-sertoli-cells
#12
Alison Vanlaeys, Florine Dubuisson, Gilles-Eric Seralini, Carine Travert
Roundup and Glyphogan are glyphosate-based herbicides containing the same concentration of glyphosate and confidential formulants. Formulants are declared as inert diluents but some are more toxic than glyphosate, such as the family of polyethoxylated alkylamines (POEA). We tested glyphosate alone, glyphosate-based herbicide formulations and POEA on the immature mouse Sertoli cell line (TM4), at concentrations ranging from environmental to agricultural-use levels. Our results show that formulations of glyphosate-based herbicides induce TM4 mitochondrial dysfunction (like glyphosate, but to a lesser extent), disruption of cell detoxification systems, lipid droplet accumulation and mortality at sub-agricultural doses...
May 15, 2018: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/29774954/adapting-population-models-for-application-in-pesticide-risk-assessment-a-case-study-with-mead-s-milkweed
#13
Amelie Schmolke, Colleen Roy, Richard Brain, Valery Forbes
Population models can facilitate assessment of potential impacts of pesticides on populations or species rather than individuals and have been identified as important tools for pesticide risk assessment of non-target species including those listed under the Endangered Species Act (ESA). Few examples of population models developed for this specific purpose are available, however, population models are commonly used in conservation science as a tool to project the viability of populations and the long-term outcomes of management actions...
May 18, 2018: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/29773742/wicked-evolution-can-we-address-the-sociobiological-dilemma-of-pesticide-resistance
#14
REVIEW
Fred Gould, Zachary S Brown, Jennifer Kuzma
Resistance to insecticides and herbicides has cost billions of U.S. dollars in the agricultural sector and could result in millions of lives lost to insect-vectored diseases. We mostly continue to use pesticides as if resistance is a temporary issue that will be addressed by commercialization of new pesticides with novel modes of action. However, current evidence suggests that insect and weed evolution may outstrip our ability to replace outmoded chemicals and other control mechanisms. To avoid this outcome, we must address the mix of ecological, genetic, economic, and sociopolitical factors that prevent implementation of sustainable pest management practices...
May 18, 2018: Science
https://www.readbyqxmd.com/read/29772427/the-dif2ferent-behaviors-of-glyphosate-and-ampa-in-compost-amended-soil
#15
Tomas Erban, Martin Stehlik, Bruno Sopko, Martin Markovic, Marcela Seifrtova, Tatana Halesova, Pavel Kovaricek
The broad-spectrum herbicide glyphosate is one of the most widely used pesticides. Both glyphosate and its major metabolite, aminomethylphosphonic acid (AMPA), persist in waters; thus, their environmental fates are of interest. We investigated the influence of compost dose, sampling depth, moisture and saturated hydraulic conductivity (Ks ) on the persistence of these substances. The amounts of AMPA quantified by triple quadrupole liquid chromatography-mass spectrometry (LC-QqQ-MS/MS) using isotopically labeled extraction standards were higher than those of glyphosate and differed among the samples...
May 4, 2018: Chemosphere
https://www.readbyqxmd.com/read/29765632/determination-of-carcinogenic-herbicides-in-milk-samples-using-green-non-ionic-silicone-surfactant-of-cloud-point-extraction-and-spectrophotometry
#16
N I Mohd, N N M Zain, M Raoov, S Mohamad
A new cloud point methodology was successfully used for the extraction of carcinogenic pesticides in milk samples as a prior step to their determination by spectrophotometry. In this work, non-ionic silicone surfactant, also known as 3-(3-hydroxypropyl-heptatrimethylxyloxane), was chosen as a green extraction solvent because of its structure and properties. The effect of different parameters, such as the type of surfactant, concentration and volume of surfactant, pH, salt, temperature, incubation time and water content on the cloud point extraction of carcinogenic pesticides such as atrazine and propazine, was studied in detail and a set of optimum conditions was established...
April 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29763631/safety-evaluation-of-genetically-modified-das-40278-9-maize-in-a-subchronic-rodent-feeding-study
#17
Shiying Zou, Tianqi Lang, Xu Liu, Kunlun Huang, Xiaoyun He
Genetically modified (GM) maize, DAS-40278-9, expresses the aryloxyalkanoate dioxygenase-1 (AAD-1) protein, which confers tolerance to 2,4-dichlorophenoxyacetic acid (2,4-D) and aryloxyphenoxypropionate (AOPP) herbicides. The aad-1 gene, which expresses the AAD-1 protein, was derived from Gram-negative soil bacterium, Sphingobium herbicidovorans. A 90-day sub-chronic toxicity study was conducted on rats as a component of the safety evaluation of DAS-40278-9 maize. Rats were given formulated diets containing maize grain from DAS-40278-9 or a non-GM near isogenic control comparator at an incorporation rate of 12...
May 12, 2018: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29762021/spatial-and-seasonal-distributions-of-current-use-pesticides-cups-in-the-atmospheric-particulate-phase-in-the-great-lakes-region
#18
Shaorui Wang, Amina Salamova, Ronald A Hites, Marta Venier
This study examined spatial and seasonal variations of current use pesticdes (CUPs) CUPs levels in the atmospheric particulate phase in the Great Lakes basin. Twenty-four hour air samples were collected at six sites (two urban, two rural, and two remote) in 2015. The concentrations of 15 CUPs, including nine pyrethroid insecticides, four herbicides, one organophosphate insecticide, and one fungicide, were measured. The total CUPs concentrations were higher at the urban sites (0.38-1760 pg/m3 ) than at the rural and remote sites (0...
May 15, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29761542/ameliorative-effect-of-resveratrol-on-testicular-oxidative-stress-spermatological-parameters-and-dna-damage-in-glyphosate-based-herbicide-exposed-rats
#19
F Avdatek, Y O Birdane, R Türkmen, H H Demirel
In this study, the reproductive impacts of being exposed to glyphosate (GLF) and the protective impacts of resveratrol (RES) were assessed in 28 Wistar male rats, which were equally separated into four groups. Control group were fed normal diet without GLF or RES, group II received normal feed containing 20 mg kg-1 daily-1 RES, group III received normal feed containing 375 mg kg-1 daily-1 GLF, and group IV received normal feed containing 375 mg kg-1 daily-1 GLF+20 mg kg-1 daily-1 RES. GLF administration decreased sperm motility, sperm plasma membrane integrity, glutathione level and superoxide dismutase in the testicular tissue of rats...
May 14, 2018: Andrologia
https://www.readbyqxmd.com/read/29759229/evaluation-of-polar-organic-chemical-integrative-and-hollow-fibre-samplers-for-the-determination-of-a-wide-variety-of-organic-polar-compounds-in-seawater
#20
Leire Mijangos, Haizea Ziarrusta, Ailette Prieto, Oihane Zugazua, Olatz Zuloaga, Maitane Olivares, Aresatz Usobiaga, Albrecht Paschke, Nestor Etxebarria
The calibration of two passive samplers for the determination of 20 emerging organic compounds in seawater is described in this work: i) a new version of polar organic chemical integrative sampler (POCIS) containing 100 mg of mixed-mode anion exchanger (Strata X-AW) and 100 mg of polymeric HLB (Plexa) sorbent materials and using a highly porous Nylon membrane (30-μm pore size) and ii) polyethersulfone (PES) hollow fibre. Among the studied contaminants, herbicides, hormones, life style products (stimulants and artificial sweeteners), industrial chemicals (corrosion inhibitor and fluorinated compounds), personal care products and several pharmaceuticals were included...
August 1, 2018: Talanta
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