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https://www.readbyqxmd.com/read/29792725/novel-breast-imaging-and-machine-learning-predicting-breast-lesion-malignancy-at-cone-beam-ct-using-machine-learning-techniques
#1
Johannes Uhlig, Annemarie Uhlig, Meike Kunze, Tim Beissbarth, Uwe Fischer, Joachim Lotz, Susanne Wienbeck
OBJECTIVE: The purpose of this study is to evaluate the diagnostic performance of machine learning techniques for malignancy prediction at breast cone-beam CT (CBCT) and to compare them to human readers. SUBJECTS AND METHODS: Five machine learning techniques, including random forests, back propagation neural networks (BPN), extreme learning machines, support vector machines, and K-nearest neighbors, were used to train diagnostic models on a clinical breast CBCT dataset with internal validation by repeated 10-fold cross-validation...
May 24, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29792345/dysembryoplastic-neuroepithelial-tumours-clinical-radiological-pathological-features-and-outcome
#2
Cihan Isler, Ozdem Erturk Cetin, Doga Ugurlar, Cigdem Ozkara, Nil Comunoglu, Osman Kizilkilic, Buge Oz, Yasemin Kayadibi, Taner Tanriverdi, Mustafa Uzan
OBJECT: To analyse the clinical, imaging and histopathological data of patients who were diagnosed to have Dysembrioplastic Neuroepithelial Tumour (DNET) and underwent surgery between 1995-2015. MATERIALS AND METHODS: Age at seizure onset, age at surgery, gender, disease duration, seizure outcome of 44 patients were analysed together with Magnetic Resonance Imaging (MRI) of 21 patients. MRI types were classified as type 1 (cystic/polycystic-like, well-delineated, strongly hypointense T1), type 2 (nodularlike,heterogeneous), type 3 (dysplastic-like, iso/hyposignal T1, poor delineation, gray-white matter blurring)...
May 24, 2018: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29792208/automated-chest-screening-based-on-a-hybrid-model-of-transfer-learning-and-convolutional-sparse-denoising-autoencoder
#3
Changmiao Wang, Ahmed Elazab, Fucang Jia, Jianhuang Wu, Qingmao Hu
OBJECTIVE: In this paper, we aim to investigate the effect of computer-aided triage system, which is implemented for the health checkup of lung lesions involving tens of thousands of chest X-rays (CXRs) that are required for diagnosis. Therefore, high accuracy of diagnosis by an automated system can reduce the radiologist's workload on scrutinizing the medical images. METHOD: We present a deep learning model in order to efficiently detect abnormal levels or identify normal levels during mass chest screening so as to obtain the probability confidence of the CXRs...
May 23, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29792179/hopkins-syndrome-following-the-first-episode-of-bronchial-asthma-associated-with-enterovirus-d68-a-case-report
#4
Fumie Hayashi, Shintaro Hayashi, Dai Matsuse, Ryo Yamasaki, Keiji Yonekura, Jun-Ichi Kira
BACKGROUND: Hopkins syndrome (HS) is a rare disorder presenting with acute flaccid paralysis of the limbs following an asthma attack. Neurologists encounter a diagnostic challenge if patients without a history of bronchial asthma develop neurologic features mimicking HS following acute respiratory distress. We report a case of HS occurring after a first episode of bronchial asthma associated with enterovirus D68 infection. CASE PRESENTATION: A 5-year-old girl developed acute respiratory distress...
May 23, 2018: BMC Neurology
https://www.readbyqxmd.com/read/29791948/multiple-sclerosis
#5
Bassem I Yamout, Raed Alroughani
Multiple sclerosis (MS) is a chronic central nervous system inflammatory disease of autoimmune etiology, mediated by activated T cells with evolving evidence of a significant contribution from B cells and cells of the innate immune system. The disease is thought to be due to a complex interaction between different genetic and environmental factors. The prevalence of MS is rising all over the world, due on one hand to earlier diagnosis and prolonged survival, and on the other to a true increase in incidence of the disease...
April 2018: Seminars in Neurology
https://www.readbyqxmd.com/read/29791933/infantile-basal-ganglia-stroke-after-mild-head-trauma-associated-with-mineralizing-angiopathy-of-lenticulostriate-arteries-an-under-recognized-entity
#6
Sandra P Toelle, Tamara Avetisyan, Nune Kuyumjyan, Biayna Sukhudyan, Eugen Boltshauser, Annette Hackenberg
Basal ganglia infarction in young children, mostly after mild head trauma, has been repeatedly reported. The pathogenesis and the risk factors are not fully understood. Lenticulostriate vasculopathy, usually referred to as basal ganglia calcification, is discussed as one of them. We describe five young (7-13 months old on presentation) male children who suffered from hemiparesis due to ischemic stroke of the basal ganglia, four of them after minor head trauma. All of them had calcification in the basal ganglia visible on computed tomography or cranial ultrasound but not on magnetic resonance imaging...
May 23, 2018: Neuropediatrics
https://www.readbyqxmd.com/read/29790997/a-multi-institutional-study-of-independent-calculation-verification-in-inhomogeneous-media-using-a-simple-and-effective-method-of-heterogeneity-correction-integrated-with-the-clarkson-method
#7
Shunta Jinno, Hidenobu Tachibana, Shunsuke Moriya, Norifumi Mizuno, Ryo Takahashi, Tatsuya Kamima, Satoru Ishibashi, Masanori Sato
In inhomogeneous media, there is often a large systematic difference in the dose between the conventional Clarkson algorithm (C-Clarkson) for independent calculation verification and the superposition-based algorithms of treatment planning systems (TPSs). These treatment site-dependent differences increase the complexity of the radiotherapy planning secondary check. We developed a simple and effective method of heterogeneity correction integrated with the Clarkson algorithm (L-Clarkson) to account for the effects of heterogeneity in the lateral dimension, and performed a multi-institutional study to evaluate the effectiveness of the method...
May 21, 2018: Journal of Radiation Research
https://www.readbyqxmd.com/read/29790456/evaluation-of-neuroimaging-findings-of-central-nervous-system-complications-in-heart-transplant-recipients
#8
Hale Turnaoglu, Ahmet Muhtesem Agildere, Feride Kural Rahatli, Fuldem Yildirim Donmez, Ruhsen Ocal, Taner Sezer, Ufuk Can, Atilla Sezgin, Sait Aslamaci
OBJECTIVES: In this study, we presented neuroradiologic findings and diagnoses of neurologic complications in a series of heart transplant recipients. MATERIALS AND METHODS: A retrospective review was conducted at Başkent University Hospital. We searched the hospital and radiology databases and identified 109 heart transplant recipients. Thirty-one of these recipients had neuroradiologic evaluations secondary to presentation of neurologic symptoms after heart transplant, with 18 patients evaluated with computed tomography and 22 patients evaluated with magnetic resonance imaging (overlap of imaging-defined groups occurred in 9 recipients)...
May 23, 2018: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29790353/-back-pain-treatment
#9
Marek Hakl
Spine pain is one of the most common medical problems. Yearly incidence is reported between 15 and 45 %, lifelong is 60-90 %. Neurological examination, radiology examination, CT or magnetic resonance imaging are the basic diagnostics. Acute back pain is usually treated monotherapeutically, NSAIDs is the base. Chronic back pain treatment is multidisciplinary, it combines pharmacotherapy, physiotherapy, psychotherapy and other methods. In pharmacotherapy we proceed according to the WHO three-step ladder, including strong opioid medication for strong back pain...
2018: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/29790149/survival-after-secondary-cytoreductive-surgery-and-chemotherapy-compared-with-chemotherapy-alone-for-first-recurrence-in-patients-with-platinum-sensitive-epithelial-ovarian-cancer-and-no-residuals-after-primary-treatment-a-registry-based-study
#10
Witold Szczesny, Hilde Langseth, Tor Å Myklebust, Janne Kaern, Claes Tropé, Torbjørn Paulsen
INTRODUCTION: To investigate whether secondary cytoreductive surgery and platinum-based chemotherapy improved survival among patients with recurrent, platinum-sensitive epithelial ovarian cancer compared with those who received platinum-based chemotherapy alone, and to identify possible predictors for selection to secondary cytoreductive surgery. MATERIAL AND METHODS: We included 397 patients who had a primary diagnosis of FIGO stage I-IV epithelial ovarian cancer recorded in the Cancer Registry of Norway between 1 January 2002 and 31 December 2012, received primary surgery with no residuals followed by platinum-based chemotherapy, had first recurrence six or more months after completion of primary platinum-based chemotherapy, and received secondary treatment with either secondary cytoreductive surgery and platinum-based chemotherapy (secondary cytoreductive surgery+platinum-based chemotherapy group) or platinum-based chemotherapy alone (platinum-based chemotherapy group)...
May 22, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29789966/beh%C3%A3-et-s-syndrome-and-nervous-system-involvement
#11
REVIEW
Uğur Uygunoğlu, Aksel Siva
PURPOSE OF REVIEW: Although Behçet's syndrome (BS) is classified as a rare disease in European countries and the USA, its neurologic involvement "neuro-Behçet's syndrome (NBS)" is commonly included in the differential diagnosis of many inflammatory and vascular central nervous system (CNS) disorders. Clinical and neuroimaging findings support two major forms of NBS: parenchymal NBS (p-NBS) and an extra-parenchymal form that presents with cerebral venous sinus thrombosis (CVST)...
May 23, 2018: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/29789895/diffusion-weighted-imaging-determinants-for-acute-ischemic-stroke-diagnosis-in-the-emergency-room
#12
Alejandro M Brunser, Gabriel Cavada, Paula Muñoz Venturelli, Verónica Olavarría, Alexis Rojo, Juan Almeida, Violeta Díaz, Arnold Hoppe, Pablo Lavados
PURPOSE: The aim of this study was to investigate the clinical-radiological determinants of diffusion-weighted image (DWI) abnormalities in patients with suspected acute ischemic stroke (AIS) seen at the emergency room (ER). METHODS: During the study period, 882 consecutive patients were screened at Clínica Alemana de Santiago, Chile; 786 had AIS and 711 (90.4%) were included. RESULTS: DWI demonstrated 87.3% sensitivity and 99.0% specificity, with a positive likelihood ratio of 79 and a negative likelihood ratio of 0...
May 22, 2018: Neuroradiology
https://www.readbyqxmd.com/read/29789859/fibrous-dysplasia-an-unusual-case-of-a-very-aggressive-form-with-costo-vertebral-joint-destruction-and-invasion-of-the-contralateral-d7-vertebral-body
#13
Carmine Zoccali, Dario Attala, Barbara Rossi, Giovanni Zoccali, Virginia Ferraresi
Fibrous dysplasia (FD) is a benign fibro-osseous disease of the bone that may be solitary or multicentric. It is important to distinguish this type of lesion from low-grade osteosarcomas (LGOS) and from secondary sarcomas, because malignant transformation has rarely been reported. It is classically described as having a ground-glass appearance, endosteal scalloping, and thinning of the cortex. Cortical disruption is considered evidence of malignancy, but it can also be present in benign FD with aggressive behavior...
May 23, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29789768/radiological-and-clinical-findings-following-rectal-contact-x-ray-brachytherapy-papillon-technique-how-to-assess-response
#14
Matt J D Dunstan, Tim A Rockall, Kate Potter, Alexandra J Stewart
Purpose: Rectal contact X-ray brachytherapy (Papillon radiotherapy) has recently received approval from the National Institute for Health and Care Excellence. In particular, it is suitable for elderly patients who are high-risk for a major operation, but it may also be undertaken for patients who wish to avoid a stoma. It is imperative to be able to identify clinical response or tumor regrowth on surveillance magnetic resonance imaging (MRI) and sigmoidoscopy. This article aims to help clinicians to interpret MRIs and endoscopic appearances following Papillon radiotherapy...
April 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29788958/langerhans-cell-histiocytosis-at-l5-vertebra-treated-with-en-bloc-vertebral-resection-a-case-report
#15
Lunhao Chen, Zhong Chen, Yue Wang
BACKGROUND: Langerhans cell histiocytosis (LCH) in adult lumbar spine is extremely rare, and optimal treatments remain unclear. In literature, only a few cases of lumbar spine LCH were treated using surgery but en bloc vertebral resection has not been used. CASE PRESENTATION: A 50-year-old man presented with unbearable radiating pain at his right leg. Radiological studies revealed a solitary osteolytic lesion, which was moderately enhanced on contrast MR imaging and hyper-metabolic on PET/CT, at the right L5 vertebral body and arch...
May 22, 2018: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29788907/mycobacterium-avium-complex-vertebral-osteomyelitis-in-the-absence-of-hiv-infection-a-case-report-and-review
#16
Megan E Gray, Peter W Liu, Brian Wispelwey
BACKGROUND: Mycobacterium Avium Complex (MAC) is an established microbiologic cause of pulmonary disease, lymphadenitis, and disseminated disease in cases of advanced immune suppression. However, MAC manifesting as vertebral osteomyelitis is less common, and is particularly rare in the absence of Acquired Immunodeficiency Syndrome (AIDS). Prompt diagnosis of MAC vertebral osteomyelitis is challenging, but necessary to prevent serious morbidity or mortality. CASE PRESENTATION: We report a case of MAC osteomyelitis of the lumbar spine in a 70-year-old woman on extended duration corticosteroid therapy for systemic lupus erythematosus who presented with progressive back pain...
May 22, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29788336/microsurgical-resection-of-posterior-third-ventricular-pineal-region-papillary-tumor-via-supracerebellar-infratentorial-approach-3-dimensional-operative-video
#17
Sima Sayyahmelli, Ihsan Dogan, Mustafa K Baskaya
The posterior third ventricle and pineal region can harbor different pathologies. The supracerebellar infratentorial approach allows a direct access to the pineal region and posterior third ventricle and provides wide exposure of the arachnoid planes and deep venous system. In this 3-dimensional video, we present a patient with posterior third ventricular/pineal region tumor who underwent microsurgical resection via supracerebellar infratentorial approach. The patient is a 28-year-old woman with history of hydrocephalus who underwent endoscopic third ventriculostomy and biopsy at an outside hospital...
May 18, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29786814/predictive-value-of-preoperative-neutrophil-to-lymphocyte-ratio-while-detecting-bowel-resection-in-hernia-with-intestinal-incarceration
#18
Hande Köksal, Derviş Ateş, Emet Ebru Nazik, İlknur Küçükosmanoğlu, Serap Melek Doğan, Osman Doğru
BACKGROUND: The aim of this study was to evaluate the relationship between preoperative hematological inflammatory markers of the patients who underwent a surgery for incarcerated hernia and intestinal resection requirement. METHODS: The data of 102 patients who underwent a surgery for incarcerated hernia were retrospectively evaluated. Whole blood cell counts were preoperatively measured, and operation types and pathology results were recorded. The patients with intestinal resections were compared with those without any resection in terms of leukocyte number, neutrophil rate, red cell distribution width (RDW), platelet distribution width, neutrophil-to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and mean platelet volume (MPV)...
May 2018: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/29786591/-patient-with-spine-pain-and-magnetic-resonance-imaging-result
#19
Anna Babińska, Wojciech Wawrzynek, Jarosław Skupiński, Sabina Kasprowska, Małgorzata Piechota, Beata Łabuz-Roszak
Degenerative spine disease is a serious social problem. In most cases, it causes pain and neurological symptoms. Most patients are therefore referred for magnetic resonance imaging (MRI). The article discusses the relationship between back pain and magnetic resonance changes. The signification of some of the radiological symptoms remains controversial. Some of them are markers of acute pain, others may be clinically insignificant, occurring with age. Authors presents some of the magnetic resonance alterations and based on the latest articles discusses their clinical significance...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29786482/human-epidermal-growth-factor-2-positive-breast-cancer-with-mammographic-microcalcification-relationship-to-pathologic-complete-response-after-neoadjuvant-chemotherapy
#20
Fayyaz A K Mazari, Nisha Sharma, David Dodwell, Kieran Horgan
Purpose To determine the relationship between the presence or absence of mammographic calcifications in human epidermal growth factor receptor 2 (HER2)-positive breast cancers and pathologic complete response (pCR) to neoadjuvant chemotherapy and to determine other tumor and clinical characteristics that may be predictive of such a response. Materials and Methods A database of all patients with HER2-positive breast cancer who underwent neoadjuvant chemotherapy between 2007 and 2015 was retrospectively reviewed...
May 16, 2018: Radiology
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