keyword
https://read.qxmd.com/read/38645511/resection-of-supratentorial-high-grade-gliomas-availing-of-neuronavigation-matched-intraoperative-ultrasound-and-fluorescein-how-far-is-it-safe-to-push-the-resection
#21
JOURNAL ARTICLE
Alessandro Pesce, Mauro Palmieri, Andrea Pietrantonio, Silvia Ciarlo, Maurizio Salvati, Angelo Pompucci
BACKGROUND: High-Grade Gliomas are the most common primary brain malignancies and despite the multimodal treatment, and the increasing amount of adjuvant treatment options the overall prognosis remains dismal. The present investigation aims to analyze the safety profile of the use of intraoperative ultrasounds (Io-US) in a homogeneous and matched cohort of patients suffering from High-grade gliomas (HGG) operated on with or without the aid of Io-US and Fluorescein in specific relation to the incidence of neurological and functional status sequelae...
July 2024: World neurosurgery: X
https://read.qxmd.com/read/38644447/efficacy-and-utility-of-antifibrinolytics-in-pediatric-spine-surgery-a-systematic-review-and-network-meta-analysis
#22
JOURNAL ARTICLE
Sepehr Aghajanian, Fateme Mohammadifard, Omid Kohandel Gargari, Arvin Naeimi, Ayad Bahadorimonfared, Aladine A Elsamadicy
Antifibrinolytics have gained increasing attention in minimizing blood loss and mitigating the risks associated with massive transfusions, including infection and coagulopathy in pediatric patients undergoing spine surgery. Nevertheless, the selection of optimal agent is still a matter of debate. We aim to review the utility of these agents and compare the efficacy of antifibrinolytics in pediatric and adolescent spine surgeries. A comprehensive search was performed in Scopus, Web of Science, and MEDLINE databases for relevant works...
April 22, 2024: Neurosurgical Review
https://read.qxmd.com/read/38644441/low-surgical-weight-associated-with-etv-failure-in-pediatric-hydrocephalus-patients
#23
JOURNAL ARTICLE
Hannah Black, Benjamin Succop, Caren M Stuebe, Andrea Torres, Andrew Caddell, Carolyn Quinsey
The use of endoscopic third ventriculostomy (ETV) for treatment of pediatric hydrocephalus has higher failure rates in younger patients. Here we investigate the impact of select perioperative variables, specifically gestational age, chronological age, birth weight, and surgical weight, on ETV failure rates. A retrospective review was performed on patients treated with ETV - with or without choroid plexus cauterization (CPC) - from 2010 to 2021 at a large academic center. Analyses included Cox regression for independent predictors and Kaplan-Meier survival curves for time to-event outcomes...
April 22, 2024: Neurosurgical Review
https://read.qxmd.com/read/38644373/amyotrophic-lateral-sclerosis-stratification-unveiling-patterns-with-virome-inflammation-and-metabolism-molecules
#24
JOURNAL ARTICLE
Elena Niccolai, Matteo Pedone, Ilaria Martinelli, Giulia Nannini, Simone Baldi, Cecilia Simonini, Leandro Di Gloria, Elisabetta Zucchi, Matteo Ramazzotti, Pietro Giorgio Spezia, Fabrizio Maggi, Gianluca Quaranta, Luca Masucci, Gianluca Bartolucci, Francesco Claudio Stingo, Jessica Mandrioli, Amedeo Amedei
Amyotrophic lateral sclerosis (ALS) is an untreatable and clinically heterogeneous condition primarily affecting motor neurons. The ongoing quest for reliable biomarkers that mirror the disease status and progression has led to investigations that extend beyond motor neurons' pathology, encompassing broader systemic factors such as metabolism, immunity, and the microbiome. Our study contributes to this effort by examining the potential role of microbiome-related components, including viral elements, such as torque tenovirus (TTV), and various inflammatory factors, in ALS...
April 21, 2024: Journal of Neurology
https://read.qxmd.com/read/38643445/age-specific-prevalence-of-the-different-clinical-presentations-of-ad-and-ftd-in-young-onset-dementia
#25
JOURNAL ARTICLE
Giovanna Zamboni, Riccardo Maramotti, Simone Salemme, Manuela Tondelli, Giorgia Adani, Giulia Vinceti, Chiara Carbone, Tommaso Filippini, Marco Vinceti, Giuseppe Pagnoni, Annalisa Chiari
BACKGROUND: Studies have shown that the prevalence of all-variants Alzheimer's disease (AD) and frontotemporal dementia (FTD) both increase with age, even before the age of 65. However, it is not known whether their different clinical presentations all increase in prevalence with age in the same way. METHODS: We studied the prevalence of the different clinical presentations of young-onset AD and FTD by 5-year age groups in a population-based study identifying all dementia patients with a diagnosis of AD and FTD and symptoms onset before age 65 in the Modena province, Italy...
April 21, 2024: Journal of Neurology
https://read.qxmd.com/read/38643444/non-invasive-biomarkers-for-spontaneous-intracranial-hypotension-sih-through-phase-contrast-mri
#26
JOURNAL ARTICLE
Katharina Wolf, Florian Volz, Niklas Lützen, Hansjoerg Mast, Marco Reisert, Amir El Rahal, Christian Fung, Mukesch J Shah, Jürgen Beck, Horst Urbach
BACKGROUND AND OBJECTIVE: Spontaneous intracranial hypotension (SIH) is an underdiagnosed disease. To depict the accurate diagnosis can be demanding; especially the detection of CSF-venous fistulas poses many challenges. Potential dynamic biomarkers have been identified through non-invasive phase-contrast MRI in a limited subset of SIH patients with evidence of spinal longitudinal extradural collection. This study aimed to explore these biomarkers related to spinal cord motion and CSF velocities in a broader SIH cohort...
April 21, 2024: Journal of Neurology
https://read.qxmd.com/read/38642835/single-center-experience-in-resection-of-120-cases-of-intradural-spinal-tumors
#27
JOURNAL ARTICLE
Mirza Pojskić, Miriam Bopp, Benjamin Saß, Christopher Nimsky
BACKGROUND: Our study presents a single center experience in resection of intradural spinal tumors either with or without using intraoperative CT (iCT)-based registration and microscope-based augmented reality (AR). Microscope-based AR was recently described for improved orientation in the operative field in spine surgery, using superimposed images of segmented structures of interest in a two- (2D) or three-dimensional (3D) mode. MATERIALS AND METHODS: All patients who underwent surgery for resection of intradural spinal tumors at our department were retrospectively included in the study...
April 18, 2024: World Neurosurgery
https://read.qxmd.com/read/38641368/contribution-of-basal-ganglia-activity-to-rem-sleep-disorder-in-parkinson-s-disease
#28
JOURNAL ARTICLE
Zixiao Yin, Tianshuo Yuan, Anchao Yang, Yichen Xu, Guanyu Zhu, Qi An, Ruoyu Ma, Yifei Gan, Lin Shi, Yutong Bai, Ning Zhang, Chunxue Wang, Yin Jiang, Fangang Meng, Wolf-Julian Neumann, Huiling Tan, Jian-Guo Zhang
BACKGROUND: Rapid eye movement (REM) sleep behaviour disorder (RBD) is one of the most common sleep problems and represents a key prodromal marker in Parkinson's disease (PD). It remains unclear whether and how basal ganglia nuclei, structures that are directly involved in the pathology of PD, are implicated in the occurrence of RBD. METHOD: Here, in parallel with whole-night video polysomnography, we recorded local field potentials from two major basal ganglia structures, the globus pallidus internus and subthalamic nucleus, in two cohorts of patients with PD who had varied severity of RBD...
April 19, 2024: Journal of Neurology, Neurosurgery, and Psychiatry
https://read.qxmd.com/read/38641336/clinico-radiologic-spectrum-and-outcome-of-paediatric-acquired-demyelinating-disorders-ads-of-central-nervous-system-a-retrospective-indian-tertiary-care-hospital-cohort
#29
JOURNAL ARTICLE
Prithviraj R Prithviraj, Bidisha Banerjee, Ullas V Acharya, Muhammed Hafis, Sruthi K Sasidharan
UNLABELLED: Paediatric acquired demyelinating syndrome(ADS) constitute group of treatable disorders with acute neurologic dysfunction. Neuroimaging has played significant role in diagnosis of ADS. We describe clinico-radiologic spectrum, outcome and compare the groups Acute disseminated encephalomyelitis (ADEM), Neuromyelitis-optica-spectrum disorder (NMOSD), clinically-isolated-syndrome (CIS), Multiple sclerosis (MS) and Myelin-oligodendrocyte-glycoprotein antibody associated disorders (MOGAD)...
April 19, 2024: Neuropediatrics
https://read.qxmd.com/read/38641246/temporo-parieto-occipital-disconnection-tpo-by-robot-assisted-magnetic-resonance-imaging-guided-laser-interstitial-thermal-therapy-mriglitt-for-refractory-epilepsy-in-a-pediatric-patient-proof-of-principle-case-report-and-surgical-nuances
#30
JOURNAL ARTICLE
Santiago Candela-Cantó, José Hinojosa, Jordi Muchart, Cristina Jou, Laura Palau, Carlos Valera, Cecilia Flores, Andrea Palacio-Navarro, María Alejandra Climent, Anna Pascual, Adrià Gonzalez, Diego Culebras, Mariana Alamar, Victoria Becerra, Javier Aparicio, Jordi Rumià
Magnetic resonance imaging-guided laser interstitial thermal therapy (MRIgLITT) has been proven safe and effective for the treatment of focal epilepsy of different etiologies. It has also been used to disconnect brain tissue in more extensive or diffuse epilepsy, such as corpus callosotomy and hemispherotomy. In this study, we report a case of temporo-parieto-occipital disconnection (TPO) surgery performed using MRIgLITT assisted by a robotic arm for refractory epilepsy of the posterior quadrant. A highly realistic cadaver simulation was performed before the actual surgery...
April 17, 2024: World Neurosurgery
https://read.qxmd.com/read/38641242/clinical-efficacy-of-neuroendoscopy-combined-with-intracranial-pressure-monitoring-for-the-treatment-of-hypertensive-intracerebral-hemorrhage
#31
JOURNAL ARTICLE
Liang Xu, Xinfeng Lu, Chenggang Zhang, Weidong Wang
OBJECTIVE: To compare the differences in postoperative complications and prognosis between patients treated with neuroendoscopy versus conventional craniotomy surgery for hypertensive intracerebral hemorrhage (HICH). METHODS: In this retrospective study, a total of 107 patients with HICH were included. Among them, 58 underwent neuroendoscopy (Group A), while 49 underwent conventional craniotomy under microscopic guidance (Group B). Intracranial pressure monitoring (ICPM) was applied in both groups...
April 17, 2024: World Neurosurgery
https://read.qxmd.com/read/38640778/predictors-of-follow-up-care-for-critically-ill-patients-with-seizures-and-epileptiform-abnormalities-on-eeg-monitoring
#32
JOURNAL ARTICLE
Hunter J Rice, Marta Bento Fernandes, Vineet Punia, Clio Rubinos, Adithya Sivaraju, Sahar F Zafar
OBJECTIVE: Post-hospitalization follow-up visits are crucial for preventing long-term complications. Patients with electrographic epileptiform abnormalities (EA) including seizures and periodic and rhythmic patterns are especially in need of follow-up for long-term seizure risk stratification and medication management. We sought to identify predictors of follow-up. METHODS: This is a retrospective cohort study of all patients (age ≥ 18 years) admitted to intensive care units that underwent continuous EEG (cEEG) monitoring at a single center between 01/2016-12/2019...
April 6, 2024: Clinical Neurology and Neurosurgery
https://read.qxmd.com/read/38640777/adult-idiopathic-bilateral-occlusion-of-foramen-of-monro-systematic-review-with-illustrative-case
#33
JOURNAL ARTICLE
Mary Angeline Luz U Hernandez, Eric Dennis C Legaspi, Kathleen Joy O Khu
BACKGROUND: Adult idiopathic occlusion of foramen of Monro (AIOFM) is a rare condition that results in hydrocephalus, and bilateral presentation is even rarer. Here we report a case of idiopathic bilateral stenosis of the foramen of Monro in an adult patient and performed a systematic literature review on the current treatment options and outcomes. METHODS: We performed a systematic review of SCOPUS, Science Direct, and PubMed databases in accordance with PRISMA guidelines...
April 7, 2024: Clinical Neurology and Neurosurgery
https://read.qxmd.com/read/38636631/readability-of-neurosurgical-patient-education-resources-by-the-american-association-of-neurological-surgeons
#34
JOURNAL ARTICLE
Ali A Mohamed, Rifa Ali, Phillip M Johansen
No abstract text is available yet for this article.
April 16, 2024: World Neurosurgery
https://read.qxmd.com/read/38636361/systemic-immune-inflammation-index-is-associated-with-cardiac-complications-following-acute-ischemic-stroke-a-retrospective-single-center-study
#35
JOURNAL ARTICLE
Xiaodi Hao, Mingfang Zhu, Zhengyu Sun, Penghui Li, Qi Meng, Leilei Tan, Chen Chen, Yakun Zhang, Lihua Yang, Jiewen Zhang, Yue Huang
BACKGROUND: Stroke-induced heart syndrome is a feared complication of ischemic stroke, that is commonly encountered and has a strong association with unfavorable prognosis. More research is needed to explore underlying mechanisms and inform clinical decision making. This study aims to explore the relationship between the early systemic immune-inflammation (SII) index and the cardiac complications after acute ischemic stroke. METHODS: Consecutive patients with acute ischemic stroke were prospectively collected from January 2020 to August 2022 and retrospectively analyzed...
April 12, 2024: Clinical Neurology and Neurosurgery
https://read.qxmd.com/read/38636360/sellar-metastasis-a-rare-intraoperative-finding-surgical-treatment-strategies-and-outcome
#36
JOURNAL ARTICLE
Kerim-Hakan Sitoci-Ficici, Christoph Sippl, Anna Prajsnar, Safwan Saffour, Stefan Linsler
The sellar region, though uncommon for metastatic spread, may become more prevalent due to longer survival of patients with metastatic malignancies. Compression of adjacent vital anatomy can cause disabling symptoms and endocrine disturbances, leading to significant morbidity METHODS: This study analyzed sellar pathologies treated via endonasal approach from January 2011 to December 2021 to assess the incidence of sellar metastases. Patient demographics, presenting symptoms, radiological and histological findings, management, and outcomes were evaluated RESULTS: Among 334 patients treated during the study period, eight (2...
April 8, 2024: Clinical Neurology and Neurosurgery
https://read.qxmd.com/read/38636359/use-of-covered-stent-grafts-to-treat-an-extracranial-carotid-artery-aneurysm-due-to-carotid-stent-deformation-a-case-report
#37
Ohju Fujita, Shigemasa Hayashi, Ryosuke Oshima, Tomoki Matsuyama, Hiroaki Tamai
No abstract text is available yet for this article.
April 2, 2024: Clinical Neurology and Neurosurgery
https://read.qxmd.com/read/38634693/the-impact-of-preprocedural-platelet-function-testing-on-periprocedural-complication-rates-associated-with-pipeline-flow-diversion-an-international-multicenter-study
#38
JOURNAL ARTICLE
Justin E Vranic, Adam A Dmytriw, Inka K Berglar, Naif M Alotaibi, Nicole M Cancelliere, Christopher J Stapleton, James D Rabinov, Pablo Harker, Rajiv Gupta, Joshua D Bernstock, Matthew J Koch, Scott B Raymond, Justin R Mascitelli, T Tyler Patterson, Joshua Seinfeld, Andrew White, David Case, Christopher Roark, Chirag D Gandhi, Fawaz Al-Mufti, Jared Cooper, Charles Matouk, Nanthiya Sujijantarat, Diego A Devia, Maria I Ocampo-Navia, Daniel E Villamizar-Torres, Juan C Puentes, Mohamed M Salem, Ammad Baig, Kareem El Namaani, Anna Luisa Kühn, Bryan Pukenas, Brian T Jankowitz, Jan Karl Burkhardt, Adnan Siddiqui, Pascal Jabbour, Jasmeet Singh, Ajit S Puri, Robert W Regenhardt, Vitor Mendes Pereira, Aman B Patel
BACKGROUND AND OBJECTIVES: Dual antiplatelet therapy (DAPT) is necessary to minimize the risk of periprocedural thromboembolic complications associated with aneurysm embolization using pipeline embolization device (PED). We aimed to assess the impact of platelet function testing (PFT) on reducing periprocedural thromboembolic complications associated with PED flow diversion in patients receiving aspirin and clopidogrel. METHODS: Patients with unruptured intracranial aneurysms requiring PED flow diversion were identified from 13 centers for retrospective evaluation...
April 18, 2024: Neurosurgery
https://read.qxmd.com/read/38634675/posterior-transdural-repair-of-a-spontaneous-ventral-thoracic-cerebrospinal-fluid-leak-2-dimensional-operative-video
#39
JOURNAL ARTICLE
David R Peters, Joe Bernard, Robert Morgan, Vincent Rossi
Spontaneous intracranial hypotension is a rare but serious condition characterized by orthostatic headaches and a variety of neurological symptoms. 1,2 Spontaneous intracranial hypotension should be considered in all patients with new onset, daily, persistent headaches, and orthostatic symptoms. It is typically caused by spontaneous spinal cerebrospinal fluid (CSF) leaks. 1,2 Traditional first-line treatments include hydration, bedrest, epidural blood patches, and fibrin glue injections. However, refractory cases often require surgical intervention, especially those caused by a small ventral osteophyte, which is classified as a type 1 leak...
April 18, 2024: Operative Neurosurgery (Hagerstown, Md.)
https://read.qxmd.com/read/38632126/effect-of-siponimod-on-lymphocyte-subsets-in-active-secondary-progressive-multiple-sclerosis-and-clinical-implications
#40
JOURNAL ARTICLE
Antonio Luca Spiezia, Giulia Scalia, Maria Petracca, Daniele Caliendo, Marcello Moccia, Antonia Fiore, Vincenza Cerbone, Roberta Lanzillo, Vincenzo Brescia Morra, Antonio Carotenuto
BACKGROUND: Circulating immune cells play a pathogenic role in multiple sclerosis (MS). However, the role of specific lymphocyte subpopulations is not unveiled yet, especially in progressive stages. We aimed to investigate lymphocyte changes during siponimod treatment in active secondary progressive MS (aSPMS) and their associations with clinical outcomes. METHODS: We enrolled 46 aSPMS patients starting on siponimod treatment with at least 6 months of follow-up and two visits within the scheduled timeframes and 14 sex- and age-matched healthy controls (HCs)...
April 17, 2024: Journal of Neurology
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