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https://www.readbyqxmd.com/read/28741279/identification-of-lead-molecules-in-garcinia-mangostana-l-against-pancreatic-cholesterol-esterase-activity-an-in-silico-approach
#1
George Kadakasseril Varghese, Rini Abraham, Nisha N Chandran, Solomon Habtemariam
Hypercholesterolemia is one of the major risk factors for the development and progression of atherosclerosis. Hence, inhibitors of cholesterol absorption have been investigated for decades as a strategy to prevent and treat cardiovascular diseases associated with hypercholesterolemia. Cholesterol esterase (CEase) in pancreatic juice plays a vital role in the hydrolysis of dietary cholesterol esters to cholesterol and fatty acids. Since inhibition of CEase might lead to a reduction of cholesterol absorption, an attempt is made in this study to identify lead molecules of Garcinia mangostana by the in silico approach...
July 24, 2017: Interdisciplinary Sciences, Computational Life Sciences
https://www.readbyqxmd.com/read/28738569/optoacoustic-determination-of-analytical-parameters-and-physicochemical-constants-in-highly-concentrated-solutions-of-chromophores
#2
Kristina V Lobko, Mikhail A Shishkin, Tatyana A Filimonova, Dmitry S Volkov, Ivan M Pelivanov, Mikhail A Proskurnin
Determination of chromophores of various classes-rosaniline (fuchsine), cyanidin-3-O-glucoside, tris(1,10-phenanthroline) iron(II), and phenol red - in their concentrated solutions near their solubility limits is performed with the optoacoustic technique for optically dense solutions; light-absorption coefficients of samples range from 0.5 to 500cm(-1). The assessment of these substances in organo-aqueous and organic solvents is possible up to ca. 0.1molL(-1). Characteristic stability and rate constants of the chelation of iron(II) with 1,10-phenanthroline are determined...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28737734/storage-of-fruits-and-vegetables-in-refrigerator-increases-their-phenolic-acids-but-decreases-the-total-phenolics-anthocyanins-and-vitamin-c-with-subsequent-loss-of-their-antioxidant-capacity
#3
Joseph H Y Galani, Jalpesh S Patel, Nilesh J Patel, Jayant G Talati
It is of paramount importance for consumers, scientists and industrialists to understand how low-temperature storage of food items affects their bioactive compounds and properties. This study evaluated the effects of cold storage on total phenolics (TP), phenolic acids profile (PA), total anthocyanins (TA), total ascorbic acid (Vit. C) and antioxidant activity (AA) of 19 fruits and vegetables, collected from local Indian markets and stored in refrigerator (4 °C) during 15 days. Content of TP was highest in dill and amaranth and decreased (up to 29...
July 24, 2017: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/28737281/in-situ-evaluation-of-color-stability-and-hardness-decrease-of-resin-based-composites
#4
Juliana Silva Ribeiro, Sonia Luque Peralta, Vinícius Esteves Salgado, Rafael Guerra Lund
OBJECTIVE: To determine the color stability (CS) and hardness' decrease (HD) of two commercial resin-based composites (RBCs), after in situ staining conditions (SC). METHODS: Six disc-shaped specimens (6 × 2 mm) of two RBCs-Filtek Z350 XT (FZX) and IPS Empress Direct (IED)-were randomly distributed into palatal devices. Eight volunteers (aged 20-30 years) participated in this study. The in situ SC consisted of 400 mL consumption (2 × 200 mL/day) of water, orange juice, cola soda, and coffee and 140 mL consumption of red wine, 10 days each...
July 24, 2017: Journal of Esthetic and Restorative Dentistry
https://www.readbyqxmd.com/read/28737033/rapid-identification-of-meat-species-by-the-internal-extractive-electrospray-ionization-mass-spectrometry-of-hemoglobin-selectively-extracted-on-functionalized-graphene-oxide
#5
Lili Song, Jiaquan Xu, Konstantin Chingin, Tenggao Zhu, Yue Zhang, Yong Tian, Huanwen Chen, Xuwei Chen
Hemoglobin (Hb) present in the blood and meat juice samples was selectively adsorbed by graphene oxide (GO) particles functionalized with amylopectin (AP) and was sensitively detected by the direct internal extractive electrospray ionization mass spectrometry (iEESI-MS) analysis for the identification of meat type. Various samples including the whole blood samples of chicken, duck, sheep, mouse, pigeon, turtledove and meat juice mixtures were successfully identified based on the difference in molecular composition of Hb reflected in MS...
July 24, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28736041/construction-of-multilayer-alginate-hydrogel-beads-for-oral-delivery-of-probiotics-cells
#6
Yang Li, Chao Feng, Jing Li, Yuzhi Mu, Ya Liu, Ming Kong, Xiaojie Cheng, Xiguang Chen
Multilayer alginate hydrogel beads (MAHBs), which were prepared by emulsion method, had been fabricated via the ionic crosslinking between calcium ion (Ca(2+)) and carboxylic group of alginate and utilized as encapsulating material for oral delivery of a model probiotic bacteria Bifidobacterium breve. Optical and fluorescence microscopy obviously showed the microorganism cells were encapsulated in the core beads. The viability of B. breve cells encapsulated in MAHBs was significantly enhanced compared with ordinary free cultured ones, the top CFU per mL were (3...
July 20, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28732939/electromechanical-acoustical-and-thermodynamical-characterization-of-a-low-frequency-sonotrode-type-transducer-in-a-small-sonoreactor-at-different-excitation-levels-and-loading-conditions
#7
Antonio Petošić, Marko Horvat, Anet Režek Jambrak
The paper reports and compares the results of the electromechanical, acoustical and thermodynamical characterization of a low-frequency sonotrode-type ultrasonic device inside a small sonoreactor, immersed in three different loading media, namely, water, juice and milk, excited at different excitation levels, both below and above the cavitation threshold. The electroacoustic efficiency factor determined at system resonance through electromechanical characterization in degassed water as the reference medium is 88...
November 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28731231/comparative-analysis-of-juice-volatiles-in-selected-mandarins-mandarin-relatives-and-other-citrus-genotypes
#8
Yuan Yu, Jinhe Bai, Chunxian Chen, Anne Plotto, Elizabeth A Baldwin, Frederick G Gmitter
BACKGROUND: Citrus fruit flavor is an important attribute prioritized in variety improvement. This study compared juice volatiles compositions from 13 selected citrus genotypes, including six mandarins (Citrus reticulata), three sour oranges (C. aurantium), one blood orange (C. sinensis), one lime (C. limonia), one clementine (C. clementina) and one satsuma (C. unshiu). RESULTS: Large differences were observed in volatiles compositions among the citrus genotypes...
July 21, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28731060/a-juiced-up-joint-implant
#9
Dustin M Graham
No abstract text is available yet for this article.
July 20, 2017: Lab Animal
https://www.readbyqxmd.com/read/28730980/validation-of-spectrophotometric-methods-for-the-determination-of-total-polyphenol-and-total-flavonoid-content
#10
Petra Matić, Marija Sabljić, Lidija Jakobek
The aim of this study was to validate spectrophotometric methods for the measurement of total polyphenol (TP;via the Folin–Ciocalteu method) and total flavonoid (TF) content [via the aluminum chloride (AlCl₃) method]. Validation parameters of these methods were determined, including linearity, sensitivity, precision (intra-assay and intermediate), accuracy, LOD, and LOQ. For the validation process, groups of polyphenol standards were used, including phenolic acids (gallic, p-coumaric, caffeic, and chlorogenic acids), flavan-3-ols [(+)-catechin and procyanidins B1 and B2], flavonols (quercetin and quercetin-3-rutinoside), and dihydrochalcones (phloretin and phloretin-2-glucoside)...
July 20, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28728873/inactivation-of-alicyclobacillus-acidoterrestris-atcc-49025-spores-in-apple-juice-by-pulsed-light-influence-of-initial-contamination-and-required-reduction-levels
#11
Mariana I Ferrario, Sandra N Guerrero
The purpose of this study was to analyze the response of different initial contamination levels of Alicyclobacillus acidoterrestris ATCC 49025 spores in apple juice as affected by pulsed light treatment (PL, batch mode, xenon lamp, 3pulses/s, 0-71.6J/cm(2)). Biphasic and Weibull frequency distribution models were used to characterize the relationship between inoculum size and treatment time with the reductions achieved after PL exposure. Additionally, a second order polynomial model was computed to relate required PL processing time to inoculum size and requested log reductions...
July 17, 2017: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/28728684/healthful-and-unhealthful-plant-based-diets-and-the-risk-of-coronary-heart%C3%A2-disease-in-u-s-adults
#12
Ambika Satija, Shilpa N Bhupathiraju, Donna Spiegelman, Stephanie E Chiuve, JoAnn E Manson, Walter Willett, Kathryn M Rexrode, Eric B Rimm, Frank B Hu
BACKGROUND: Plant-based diets are recommended for coronary heart disease (CHD) prevention. However, not all plant foods are necessarily beneficial for health. OBJECTIVES: This study sought to examine associations between plant-based diet indices and CHD incidence. METHODS: We included 73,710 women in NHS (Nurses' Health Study) (1984 to 2012), 92,329 women in NHS2 (1991 to 2013), and 43,259 men in Health Professionals Follow-up Study (1986 to 2012), free of chronic diseases at baseline...
July 25, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28728009/bridged-rebar-graphene-functionalized-aptasensor-for-pathogenic-e-coli-o78-k80-h11-detection
#13
Harmanjit Kaur, Munish Shorie, Manju Sharma, Ashok K Ganguli, Priyanka Sabherwal
We report a novel fabrication method of functionalised Bridged Rebar Graphene (BRG) onto newly designed nanostructured aptasensor for label free impedimetric sensing of pathogenic bacteria E. coli O78:K80:H11. The chemical facilitated unscrolling of MWCNT and subsequent bridging with terephthalaldehyde (TPA) to form 3D-hierarchical BRG nanoconstruct exhibited synergistic effect by combining enhanced electrical properties and facile chemical functionality for stable bio-interface. The bacteria-DNA interactions were captured on BRG nanostructured electrode by using specific anti-E...
July 5, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28727037/assessment-of-objective-measures-of-beef-steak-juiciness-and-their-relationships-to-sensory-panel-juiciness-ratings
#14
L W Lucherk, T G O'Quinn, J F Legako, R J Rathmann, J C Brooks, M F Miller
The objective of this study was to evaluate multiple instrumental measures of beef juiciness and determine their relationships with sensory panel juiciness ratings. Treatments were selected to maximize variation in juiciness and included 5 USDA quality grades (Prime, upper two-thirds Choice, lower one-third Choice, Select, and Standard) as well as 2 enhanced Select treatments (112 and 107% of the initial raw weight) and were prepared to 3 degrees of doneness (DOD; rare [66°C], medium [71°C], and well done [77°C])...
June 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28726768/characterization-and-purification-of-bergamottin-from-citrus-grandis-l-osbeck-cv-yongjiazaoxiangyou-and-its-antiproliferative-activity-and-effect-on-glucose-consumption-in-hepg2-cells
#15
Yilong Liu, Chuanhong Ren, Yunlin Cao, Yue Wang, Wenyi Duan, Linfeng Xie, Chongde Sun, Xian Li
Bergamottin is a natural furanocoumarin compound with weak polarity. Characterization and quantification of bergamottin were carried out in different fruit tissues of various citrus cultivars. Among the four citrus tissues tested, i.e., flavedo, albedo, segment membrane (SM), and juice sacs (JS) in eight citrus cultivars, the highest bergamottin content was found in the flavedo of Citrus grandis (L.) Osbeck cv. Yongjiazaoxiangyou (YJZXY, 666.54 μg·g(-1) DW). A combination of silica gel column chromatography and high-speed counter-current chromatography (HSCCC) was established to efficiently purify bergamottin from the flavedo of YJZXY...
July 20, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28725389/quality-versus-quantity-foraging-decisions-in-the-honeybee-apis-mellifera-scutellata-feeding-on-wildflower-nectar-and-fruit-juice
#16
Kyle Shackleton, Nicholas J Balfour, Hasan Al Toufailia, Roberto Gaioski, Marcela de Matos Barbosa, Carina A de S Silva, José M S Bento, Denise A Alves, Francis L W Ratnieks
Foraging animals must often decide among resources which vary in quality and quantity. Nectar is a resource that exists along a continuum of quality in terms of sugar concentration and is the primary energy source for bees. Alternative sugar sources exist, including fruit juice, which generally has lower energetic value than nectar. We observed many honeybees (Apis mellifera scutellata) foraging on juice from fallen guava (Psidium guajava) fruit near others foraging on nectar. To investigate whether fruit and nectar offered contrasting benefits of quality and quantity, we compared honeybee foraging performance on P...
October 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/28725129/estimation-of-fluoride-concentration-in-drinking-water-and-common-beverages-in-united-arab-emirates-uae
#17
Tarun Walia, Salem Abu Fanas, Madiha Akbar, Jamal Eddin, Mohamad Adnan
OBJECTIVE: To assess fluoride concentration in drinking water which include tap water of 4 emirates - Abu Dhabi, Dubai, Sharjah and Ajman plus bottled water, commonly available soft drinks & juices in United Arab Emirates. METHODS: Five different samples of tap water collected from each of the four emirates of UAE: Ajman, Sharjah, Abu Dhabi and Dubai; twenty-two brands of bottled water and fifteen brands of popular cold beverages, purchased from different supermarkets in U...
July 2017: Saudi Dental Journal
https://www.readbyqxmd.com/read/28724468/a-combined-high-sugar-and-high-saturated-fat-dietary-pattern-is-associated-with-more-depressive-symptoms-in-a-multi-ethnic-population-the-helius-healthy-life-in-an-urban-setting-study
#18
Esther Vermeulen, Karien Stronks, Marieke B Snijder, Aart H Schene, Anja Lok, Jeanne H de Vries, Marjolein Visser, Ingeborg A Brouwer, Mary Nicolaou
OBJECTIVE: To identify a high-sugar (HS) dietary pattern, a high-saturated-fat (HF) dietary pattern and a combined high-sugar and high-saturated-fat (HSHF) dietary pattern and to explore if these dietary patterns are associated with depressive symptoms. DESIGN: We used data from the HELIUS (Healthy Life in an Urban Setting) study and included 4969 individuals aged 18-70 years. Diet was assessed using four ethnic-specific FFQ. Dietary patterns were derived using reduced rank regression with mono- and disaccharides, saturated fat and total fat as response variables...
July 20, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28724424/the-traditional-lunch-pattern-is-inversely-correlated-with-body-mass-index-in-a-population-based-study-in-brazil
#19
Roberta de Oliveira Santos, Diva Aliete Dos Santos Vieira, Andreia Alexandra Machado Miranda, Regina Mara Fisberg, Dirce Maria Marchioni, Valéria Troncoso Baltar
BACKGROUND: The association of obesity and dietary patterns has been well documented in scientific literature; however, information on the impact of meal patterns on obesity is scarce. The objective of this study was to investigate the association of adherence to lunch patterns and body mass index (BMI) in a representative sample of individuals aged 20 years or older in Sao Paulo. METHODS: Data for 933 participants were retrieved from the Health Survey of São Paulo (ISA-Capital 2008), a cross-sectional population-based survey...
July 19, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28723164/differentiation-and-identification-of-cacha%C3%A3-a-wood-extracts-using-peptide-based-receptors-and-multivariate-data-analysis
#20
Eman Ghanem, Saazina Afsah, Parisa N Fallah, Alexandria Lawrence, Elise LeBovidge, Sneha Raghunathan, Dominic Rago, Michelle A Ramirez, Mitchell Telles, Michelle Winkler, Bailey Schumm, Kiran Makhnejia, David Portillo, Rafael C Vidal, Allison Hall, Debbie Yeh, Holly Judkins, Alexandre Ataide da Silva, Douglas W Franco, Eric V Anslyn
It is becoming increasingly important to differentiate complex mixtures, especially in forensics. Cachaça, the most popular alcoholic beverage in Brazil, is made from distilled and fermented sugar cane juice. It contains a mixture of naturally occurring polyphenols known as tannins, whose composition is dictated by the type of wood used to age the beverage. These tannins can be differentiated in an Indicator Displacement Assay (IDA) using peptide-based ternary sensing ensembles. This investigation demonstrates a technique for fingerprinting the identity of the woods used to age cachaças...
May 26, 2017: ACS Sensors
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