keyword
https://read.qxmd.com/read/38479590/approaching-the-complexity-of-crimean-congo-hemorrhagic-fever-virus-serology-a-study-in-swine
#1
JOURNAL ARTICLE
Caroline Bost, Sabrina Castro-Scholten, Balal Sadeghi, David Cano-Terriza, Mario Frías, Saúl Jiménez-Ruiz, Martin H Groschup, Ignacio García-Bocanegra, Kerstin Fischer
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne zoonotic orthonairovirus of public health concern and widespread geographic distribution. Several animal species are known to seroconvert after infection with CCHFV without showing clinical symptoms. The commercial availability of a multi-species ELISA has led to an increase in recent serosurveillance studies as well as in the range of species reported to be exposed to CCHFV in the field, including wild boar (Sus scrofa). However, development and validation of confirmatory serological tests for swine based on different CCHFV antigens or test principles are hampered by the lack of defined control sera from infected and non-infected animals...
March 12, 2024: Journal of Virological Methods
https://read.qxmd.com/read/38474504/unraveling-the-dynamics-of-host-microbiota-indole-metabolism-an-investigation-of-indole-indolin-2-one-isatin-and-3-hydroxyindolin-2-one
#2
JOURNAL ARTICLE
Arnas Kunevičius, Mikas Sadauskas, Julija Raudytė, Rolandas Meškys, Aurelijus Burokas
The gut microbiota produces a variety of bioactive molecules that facilitate host-microbiota interaction. Indole and its metabolites are focused as possible biomarkers for various diseases. However, data on indole metabolism and individual metabolites remain limited. Hence, we investigated the metabolism and distribution of indole, indolin-2-one, isatin, and 3-hydroxyindolin-2-one. First, we orally administered a high dose of indole into C57BL/6J mice and measured the concentrations of indole metabolites in the brain, liver, plasma, large and small intestines, and cecum at multiple time points using HPLC/MS...
February 24, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38457592/effect-of-antinuclear-antibody-positivity-on-antineutrophil-cytoplasmic-antibody-results-by-indirect-immunofluorescence-assay
#3
JOURNAL ARTICLE
Demet Gür Vural, Büşra Usta, Yeliz Tanriverdi Çayci, Kemal Bilgin, Asuman Birinci
BACKGROUND: The indirect immunofluorescence assay (IIFA) utilizing antineutrophil cytoplasmic antibodies (ANCA) is widely used as a diagnostic test for autoimmune vasculitis. The presence of antinuclear antibodies (ANA) might lead to a misleading interpretation of ANCA. This study aims to explore the impact of the presence of ANA on the interpretation of ANCA. METHODS: This retrospective research examined samples negative for antiMPO and antiPR3 ANCA by IIFA and explored correlations between the ANA-IIFA results and the ANCA interpretation frequencies...
March 8, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38316347/evaluation-of-immunogenicity-and-protective-efficacy-of-the-outer-membrane-porin-f-oprf-against-pseudomonas-plecoglossicida-in-large-yellow-croaker-larimichthys-crocea
#4
JOURNAL ARTICLE
Liangyin He, Jiale Kang, Xingfu Chen, Pan Qin, Xinhua Chen
Large yellow croaker (Larimichthys crocea) farming dominates the marine aquaculture industry in China. However, the epidemic outbreaks of visceral white nodules disease (VWND), caused by bacterial pathogen Pseudomonas plecoglossicida, have emerged as a significant concern within the large yellow croaker industry. Although vaccination is considered to be an effective method for preventing and controlling P. plecoglossicida infection, there is currently no commercially available vaccine targeting this bacterium...
February 3, 2024: Fish & Shellfish Immunology
https://read.qxmd.com/read/38267922/attitudes-and-barriers-to-breastfeeding-among-women-at-high-risk-for-not-breastfeeding-a-prospective-observational-study
#5
JOURNAL ARTICLE
Jessica Cole, Ateshi Bhatt, Andrew G Chapple, Sarah Buzhardt, Elizabeth F Sutton
BACKGROUND: Rates of breastfeeding are lower among minority and underserved populations in the United States. Our study objective was to assess pregnant persons attitudes and barriers to breastfeeding among a cohort at high risk for not breastfeeding. METHODS: We disseminated the Iowa Infant Feeding Attitude Scale (IIFAS) to 100 pregnant persons at least 18 years of age attending a prenatal visit in a low-resource, academic practice in south-central Louisiana (Woman's Hospital)...
January 24, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38237419/the-effectiveness-of-online-breastfeeding-education-and-support-program-on-mothers-of-preterm-infants-a-quasi-experimental-study
#6
JOURNAL ARTICLE
Jun Zhang, Yawei Li, Luyang Zhu, Yanyan Shang, Qiaoyuan Yan
OBJECTIVE: To develop a WeChat-mini-program-based Online breastfeeding education and support program and explore its impacts on promoting mothers of preterm infants' breastfeeding knowledge, attitudes, self-efficacy, and rates. DESIGN, SETTING, AND PARTICIPANTS: This was a quasi-experimentation with two-group comparisons. The eligible preterm mother-infant pairs were recruited from the NICU within seven days postpartum. The first 25 mothers admitted to the NICU during the study period were included in the control group, and the following 25 mothers were in the intervention group according to the admission order of their preterm infants...
January 11, 2024: Midwifery
https://read.qxmd.com/read/38006250/effect-of-breastfeeding-education-program-and-nurse-led-breastfeeding-online-counseling-system-bmum-for-mothers-a-randomized-controlled-study
#7
JOURNAL ARTICLE
Şahika Şimsek-Çetinkaya, Gülçin Gümüş Çaliş, Şerife Kibris
BACKGROUND: Breastfeeding is very important for maternal and infant health. With first pregnancies, many pregnant people face obstacles to achieving their breastfeeding goals. RESEARCH AIMS: We aimed to investigate the outcomes of a breastfeeding education program and nurse-led online breastfeeding counseling system (BMUM) on breastfeeding self-efficacy, attitudes about breastfeeding, breastfeeding problems, breastfeeding frequencies and postpartum depression. METHODS: This study was a randomized controlled trial...
November 25, 2023: Journal of Human Lactation
https://read.qxmd.com/read/37977254/characterization-of-a-novel-dipeptidyl-peptidase-1-of-trichinella-spiralis-and-its-participation-in-larval-invasion
#8
JOURNAL ARTICLE
Shu Wei Yan, Yong Kang Cheng, Qi Qi Lu, Ru Zhang, Ruo Dan Liu, Shao Rong Long, Zhong Quan Wang, Jing Cui
The research aimed to describe a new Trichinella spiralis dipeptidyl peptidase 1 (TsDPP1) and investigate its functions in the larval invasion of intestinal epithelial cells (IECs). The gene TsDPP1 was successfully replicated and produced in Escherichia coli BL21 (DE3), showing a strong immune response. TsDPP1 was detected in diverse stages of T. spiralis and showed significant expression in the intestine infective larvae (IIL) and adult worms at 6 days post infection, as confirmed by qPCR and Western blot analysis...
November 15, 2023: Acta Tropica
https://read.qxmd.com/read/37942283/mothers-attitudes-towards-breastfeeding-in-terms-of-health-safety-and-professional-lactation-education-a-national-survey-of-women
#9
JOURNAL ARTICLE
Anna Bednarek, Iwona Bodys-Cupak, Adrianna Serwin, Elżbieta Cipora
INTRODUCTION AND OBJECTIVE: An important role in building opinions and attitudes regarding breastfeeding by mothers is played by the medical staff taking care of the mother woman expecting a baby. Breastfeeding is a standard in infant nutrition. The knowledge and support of the medical staff can help a woman make the decision to breastfeed. At the same time, it creates conditions for an optimal working environment for medical staff, affecting the quality of care. The aim of the study was identify mothers' attitudes towards breastfeeding in the context of health safety and professional lactation education...
2023: Journal of Multidisciplinary Healthcare
https://read.qxmd.com/read/37814203/no-evidence-of-an-association-of-multiple-sclerosis-ms-with-borna-disease-virus-1-bodv-1-infections-in-patients-within-an-endemic-region-a-retrospective-pilot-study
#10
JOURNAL ARTICLE
Markus Bauswein, Gertrud Knoll, Barbara Schmidt, André Gessner, Bernhard Hemmer, Martina Flaskamp
BACKGROUND: Borna disease virus 1 (BoDV-1) causes rare human infections within endemic regions in southern and eastern Germany. The infections reported to date have been linked to severe courses of encephalitis with high mortality and mostly irreversible symptoms. Whether BoDV-1 could act as a trigger for other neurological conditions, is, however, incompletely understood. OBJECTIVES AND METHODS: In this study, we addressed the question of whether the presentation of a clinically isolated syndrome (CIS) or of multiple sclerosis (MS) might be associated with a milder course of BoDV-1 infections...
October 9, 2023: Infection
https://read.qxmd.com/read/37732061/serum-antinuclear-autoantibodies-are-associated-with-measures-of-oxidative-stress-and-lifestyle-factors-analysis-of-lipidogram2015-and-lipidogen2015-studies
#11
JOURNAL ARTICLE
Paweł Krzemień, Sławomir Kasperczyk, Maciej Banach, Aleksandra Kasperczyk, Michał Dobrakowski, Tomasz Tomasik, Adam Windak, Mirosław Mastej, Alberico Catapano, Kausik K Ray, Dimitri P Mikhailidis, Peter P Toth, George Howard, Gregory Y H Lip, Maciej Tomaszewski, Fadi J Charchar, Naveed Sattar, Bryan Williams, Thomas M MacDonald, Peter E Penson, Jacek J Jóźwiak
INTRODUCTION: Oxidative stress is one of many factors suspected to promote antinuclear autoantibody (ANA) formation. Reactive oxygen species can induce changes in the antigenic structure of macromolecules, causing the immune system to treat them as "neo-antigens" and start production of autoantibodies. This study was designed to evaluate the relationship between oxidative stress markers, lifestyle factors and the detection of ANA. MATERIAL AND METHODS: We examined measures of oxidative stress indices of free-radical damage to lipids and proteins, such as total oxidant status (TOS), concentration of protein thiol groups (PSH), and malondialdehyde (MDA), activity of superoxide dismutase (SOD) in 1731 serum samples...
2023: Archives of Medical Science: AMS
https://read.qxmd.com/read/37447377/associated-factors-of-exclusive-breastfeeding-intention-among-pregnant-women-in-najran-saudi-arabia
#12
JOURNAL ARTICLE
Heba A Ibrahim, Mohammed A Alshahrani, DaifAllah D Al-Thubaity, Samiha H Sayed, Sultan A Almedhesh, Wafaa T Elgzar
The exclusive breastfeeding (EBF) intention conceived by pregnant women is the most important predictor of breastfeeding (BF) initiation, duration, and continuation. This study explores the associated factors of EBF intention among pregnant women. This was a descriptive cross-sectional study conducted from November 2022 to January 2023 with 382 pregnant women who came to the outpatient clinic in the Maternal and Children Hospital (MCH). Four instruments were used for data collection: the Infant Feeding Intention scale, the Gender-Friendly BF Knowledge scale (GFBKS), the Iowa Infant Feeding Attitude scale (IIFAS), and the basic data questionnaire...
July 6, 2023: Nutrients
https://read.qxmd.com/read/37336684/a-novel-magnetic-bead-based-immunoprecipitation-method-for-anti-dense-fine-speckled-70-antibodies
#13
JOURNAL ARTICLE
Renfen Chen, Xiumei Wei, Cindy Yang, Khuyen Nguyen
The indirect immunofluorescence assay (IIFA) on HEp-2 cells has been widely used for screening anti-nuclear antibodies (ANA) that are associated with systemic autoimmune rheumatic diseases (SARD). Sera containing ANA display multiple distinct fluorescence patterns on HEp-2 cells. Among them, a dense fine speckled (DFS) pattern caused by anti-DFS70 antibodies has been reported to have higher prevalence in healthy individuals than in patients with SARD. This DFS pattern is often difficult to distinguish amongst other SARD-associated ANA patterns, in particular a mixed homogeneous and speckled pattern...
May 29, 2023: Pathology
https://read.qxmd.com/read/37146024/determinants-of-breastfeeding-attitudes-of-mothers-in-jordan-a-cross-sectional-study
#14
JOURNAL ARTICLE
Sireen M Alkhaldi, Oqba Al-Kuran, Mai M AlAdwan, Tala A Dabbah, Heyam F Dalky, Eiman Badran
Breastfeeding provides the optimal nutrition for an infant. However, breastfeeding practice is on decline globally. Attitude toward breastfeeding may determine the practice. This study aimed to examine postnatal mothers' attitude to breastfeeding and its determinants. A cross-sectional study was conducted, and data on attitude were collected using the Iowa Infant Feeding Attitude Scale (IIFAS). A convenience sample of 301 postnatal women were recruited from a major referral hospital in Jordan. Data on sociodemographic characteristics, pregnancy and delivery outcomes were collected...
2023: PloS One
https://read.qxmd.com/read/37111138/determinants-of-high-breastfeeding-self-efficacy-among-nursing-mothers-in-najran-saudi-arabia
#15
JOURNAL ARTICLE
DaifAllah D Al-Thubaity, Mohammed A Alshahrani, Wafaa T Elgzar, Heba A Ibrahim
UNLABELLED: Many factors have been found to correlate with satisfactory Exclusive Breastfeeding (EBF) practices. The relationships between EBF practices and associated factors are complex and multidimensional; Breastfeeding Self-Efficacy (BSE) is the most important psychological factor that may help the mother to overcome any expected barriers. This study investigates the determinants of high breastfeeding self-efficacy among Saudi nursing mothers. METHODS: This is a descriptive cross-sectional study investigating the determinant of BSE among 1577 nursing mothers in primary health centers in Najran City, Saudi Arabia...
April 15, 2023: Nutrients
https://read.qxmd.com/read/37029895/a-survey-of-breastfeeding-attitudes-and-health-locus-of-control-in-the-nigerian-population
#16
JOURNAL ARTICLE
Adenike Adegbayi, Andrew Scally, Valerie Lesk, Barbara J Stewart-Knox
OBJECTIVES: Breastfeeding is important to infant health and survival in sub-Saharan Africa. To promote breastfeeding effectively, understanding of psychological factors associated with infant feeding choices is required. This study investigated breastfeeding attitudes and health locus of control (HLoC) in a Nigerian community sample. METHODS: Men and women (N = 400) (71% female; mean age 34.2 years/ range 18-86 years) were recruited through community groups in Nigeria...
April 8, 2023: Maternal and Child Health Journal
https://read.qxmd.com/read/36997937/septin-3-autoimmunity-in-patients-with-paraneoplastic-cerebellar-ataxia
#17
JOURNAL ARTICLE
Ramona Miske, Madeleine Scharf, Kathrin Borowski, Nicole Rieckhoff, Bianca Teegen, Yvonne Denno, Christian Probst, Kersten Guthke, Ieva Didrihsone, Brigitte Wildemann, Klemens Ruprecht, Lars Komorowski, Sven Jarius
BACKGROUND: Septins are cytoskeletal proteins with filament forming capabilities, which have multiple roles during cell division, cellular polarization, morphogenesis, and membrane trafficking. Autoantibodies against septin-5 are associated with non-paraneoplastic cerebellar ataxia, and autoantibodies against septin-7 with encephalopathy with prominent neuropsychiatric features. Here, we report on newly identified autoantibodies against septin-3 in patients with paraneoplastic cerebellar ataxia...
March 30, 2023: Journal of Neuroinflammation
https://read.qxmd.com/read/36975395/newborn-feeding-knowledge-and-attitudes-among-medical-students
#18
JOURNAL ARTICLE
Henrique Pereira, Ricardo Campos, Patricia Silva, Madalena Cruz
This study sought to assess newborn feeding knowledge and attitudes among medical students. A sample of 649 Portuguese medical students completed an online survey containing a sociodemographic questionnaire, the Newborn Feeding Ability Questionnaire (NFA), and the Iowa Infant Feeding Attitudes Scale (IIFAS). The overall sample showed moderate scores for all variables. Gender analysis identified significant differences only for the dimension related to the benefits of skin-to-skin contact between mother and newborn where women scored higher...
March 5, 2023: European journal of investigation in health, psychology and education
https://read.qxmd.com/read/36906522/does-benefits-of-breastfeeding-language-or-risks-of-formula-feeding-language-promote-more-positive-attitudes-toward-breastfeeding-among-midwives-and-nurses
#19
JOURNAL ARTICLE
Ayumi Toda, Keiko Nanishi, Akira Shibanuma
BACKGROUND: Midwives and nurses are crucial in breastfeeding support. Few studies have explored appropriate language for nursing education on breastfeeding. We assessed the impact of the language used on breastfeeding attitudes among midwives and nurses. METHODS: A quasi-experimental study was conducted online in Japan among 174 midwives and nurses who had work experience in obstetrics or pediatrics. Participants were allocated to three groups to receive different text messages as the intervention (the benefit of breastfeeding for Group 1; the risk of formula feeding for Group 2; the importance of childcare for Group 3 as the comparison)...
March 11, 2023: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/36839457/seroprevalence-of-tick-borne-encephalitis-tbe-virus-antibodies-in-wild-rodents-from-two-natural-tbe-foci-in-bavaria-germany
#20
JOURNAL ARTICLE
Philipp Johannes Brandenburg, Anna Obiegala, Hannah Maureen Schmuck, Gerhard Dobler, Lidia Chitimia-Dobler, Martin Pfeffer
Tick-borne encephalitis (TBE) is Eurasia's most important tick-borne viral disease. Rodents play an important role as natural hosts. Longitudinal studies on the dynamics of the seroprevalence rates in wild rodents in natural foci over the year are rare, and the dynamics of the transmission cycle still need to be understood. To better understand the infection dynamics, rodents were captured in a capture-mark-release-recapture-study in two natural foci in Bavaria, Germany, monthly from March 2019 to October 2022...
January 25, 2023: Pathogens
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