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External tissue expander

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https://www.readbyqxmd.com/read/29064545/the-morphological-characters-of-the-male-external-genitalia-of-the-european-hedgehog-erinaceus-europaeus
#1
Ghasem Akbari, Mohammad Babaei, Nader Goodarzi
This study was conducted to depict anatomical characteristics of the penis in hedgehog. Seven sexually mature male European hedgehogs were used. Following anesthesia, the animals were scarified with chloroform inhalation. Gross penile characteristics such as length and diameter were thoroughly explored and measured using digital calipers. Tissue samples stained with Hematoxylin - Eosin and Masson's trichrome for microscopic analysis. The penis of the European hedgehog was composed of a pair of corpus cavernosum penis and the glans penis without corpus spongiosum penis...
October 24, 2017: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/29030904/development-and-maintenance-of-the-brain-s-immune-toolkit-microglia-and-non-parenchymal-brain-macrophages
#2
REVIEW
Jose P Lopez-Atalaya, Katharine E Askew K, Amanda Sierra, Diego Gomez-Nicola
Microglia and non-parenchymal macrophages located in the perivascular space, the meninges and the choroid plexus are independent immune populations that play vital roles in brain development, homeostasis, and tissue healing. Resident macrophages account for a significant proportion of cells in the brain and their density remains stable throughout the lifespan thanks to constant turnover. Microglia develop from yolk sac progenitors, later evolving through intermediate progenitors in a fine-tuned process in which intrinsic factors and external stimuli combine to progressively sculpt their cell-type specific transcriptional profiles...
October 14, 2017: Developmental Neurobiology
https://www.readbyqxmd.com/read/28841613/dedifferentiated-adipocytes-promote-adipose-tissue-generation-within-an-external-suspension-device
#3
Jingjing Ma, Yao Yao, Jing Wang, Ziqing Dong, Tao Zhou, Feng Lu, Yunjun Liao, Jianhua Gao
BACKGROUND: Mature adipocytes can dedifferentiate into fibroblast-like cells in vitro and acquire proliferation and redifferentiation/transdifferentiation abilities. A soft-tissue expander can induce adipocyte dedifferentiation in vivo. This study combined a tissue expander and an external suspension device to generate a large volume of adipose tissue. METHODS: A soft-tissue expander was implanted beneath the dorsal adipose flaps of rabbits. After 7 days of expansion, the expander was removed and an external suspension device was applied...
September 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28760620/microcontact-printing-of-polydopamine-on-thermally-expandable-hydrogels-for-controlled-cell-adhesion-and-delivery-of-geometrically-defined-microtissues
#4
Yu Bin Lee, Se-Jeong Kim, Eum Mi Kim, Hayeon Byun, Hyung-Kwan Chang, Jungyul Park, Yu Suk Choi, Heungsoo Shin
Scaffold-free harvest of microtissue with a defined structure has received a great deal of interest in cell-based assay and regenerative medicine. In this study, we developed thermally expandable hydrogels with spatially controlled cell adhesive patterns for rapid harvest of geometrically controlled microtissue. We patterned polydopamine (PD) on to the hydrogel via microcontact printing (μCP), in linear shapes with widths of 50, 100 and 200μm. The hydrogels facilitated formation of spatially controlled strip-like microtissue of human dermal fibroblasts (HDFBs)...
July 28, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28751248/reshapable-polymeric-hydrogel-for-controlled-soft-tissue-expansion-in-vitro-and-in-vivo-evaluation
#5
John Garner, Darrel Davidson, George J Eckert, Clark T Barco, Haesun Park, Kinam Park
Tissue expansion is the process by which extra skin is generated using a device that applies pressure from underneath the skin. Over the course of weeks to months, stretching by this pressure creates a flap of extra tissue that can be used to cover a defect area or enclose a permanent implant. Conventional tissue expanders require a silicone shell inflated either by external injections of saline solution or air, or by internal osmotic pressure generated by a hydrophilic polymer. In this study, a shell-free tissue expander comprised only of a chemically cross-linked biocompatible polymeric hydrogel is developed...
September 28, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28746132/three-dimensional-cross-platform-planning-for-complex-spinal-procedures-a-new-method-adaptive-to-different-navigation-systems
#6
Michael Kosterhon, Angelika Gutenberg, Sven R Kantelhardt, Jens Conrad, Amr Nimer Amr, Joachim Gawehn, Alf Giese
STUDY DESIGN: A feasibility study. OBJECTIVE: To develop a method based on the DICOM standard which transfers complex 3-dimensional (3D) trajectories and objects from external planning software to any navigation system for planning and intraoperative guidance of complex spinal procedures. SUMMARY OF BACKGROUND DATA: There have been many reports about navigation systems with embedded planning solutions but only few on how to transfer planning data generated in external software...
August 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28713235/connecting-the-brain-to-itself-through-an-emulation
#7
Mijail D Serruya
Pilot clinical trials of human patients implanted with devices that can chronically record and stimulate ensembles of hundreds to thousands of individual neurons offer the possibility of expanding the substrate of cognition. Parallel trains of firing rate activity can be delivered in real-time to an array of intermediate external modules that in turn can trigger parallel trains of stimulation back into the brain. These modules may be built in software, VLSI firmware, or biological tissue as in vitro culture preparations or in vivo ectopic construct organoids...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28667507/endoluminal-nd-yag-laser-application-in-ex-vivo-biliary-porcine-tissue
#8
Roberta Rea, Francesco Maria Di Matteo, Margareth Martino, Monica Pandolfi, Paola Saccomandi, Carla Rabitti, Anna Crescenzi, Guido Costamagna
Adequate biliary drainage with endoscopic or percutaneous placement of self-expandable metal stents represents the goal of palliation in patients with inoperable malignant obstruction of the biliary tree. As an adjunct to stenting, various tissue ablation treatments have been proposed with conflicting results. The aim of this study was to test the effect on biliary tissue of a new ablation technique based on Nd:YAG laser light delivery. The study was conducted on ex vivo specimens of 18 healthy farm pigs, using cystic ducts that are the simplest biliary structures to isolate and cannulate ex vivo...
August 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28662875/the-role-of-varicella-zoster-virus-in-the-development-of-periapical-pathoses-and-root-resorption-a-systematic-review
#9
REVIEW
Aleksandar Jakovljevic, Jovana Kuzmanovic Pficer, Irina F Dragan, Aleksandra Knezevic, Maja Miletic, Katarina Beljic-Ivanovic, Jelena Milasin, Miroslav Andric
INTRODUCTION: Varicella zoster virus (VZV) and subsequent herpes zoster (HZ) infection have been proposed as a causative agent of periapical pathoses and root resorption. This review aimed to identify, synthesize, and present a critical analysis of the available data on the association among VZV, subsequent HZ infection, and the development of periapical pathoses and root resorption and to analyze the level of evidence of available studies. METHODS: The literature search covered MEDLINE, Science Citation Index Expanded, and Scopus...
June 26, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28652140/erythropoietin-in-diabetic-retinopathy
#10
Gerard Reid, Noemi Lois
Over the past years, knowledge has expanded with regards to the multiple roles played by Erythropoietin (EPO) in the body. Once believed to be a hormone synthesised in the kidney and involved only in the modulation of erythrocyte production, it is recognised now that EPO can be produced in many tissues, including the retina, and by many cells. In these tissues EPO is released in response to "tissue injury" and appears to have protective functions. Despite the extensive research conducted to date, the cues leading to release of EPO and its effects in the normal and diseased retina have not been fully elucidated...
June 23, 2017: Vision Research
https://www.readbyqxmd.com/read/28597129/transcanal-surgery-for-vestibular-schwannomas-a-pictorial-review-of-radiological-findings-surgical-anatomy-and-comparison-to-the-traditional-translabyrinthine-approach
#11
Matteo Alicandri-Ciufelli, Gaia Federici, Lukas Anschuetz, Giacomo Pavesi, Alessandra Todeschini, Livio Presutti, Daniele Marchioni
The most popular approaches for vestibular schwannoma (VS) removal are retrosigmoid, middle cranial fossa and translabyrinthine (TL). All require a certain degree of invasivity, bone removal, or brain manipulation. Recently, the authors described the transcanal transpromontorial approaches (TTA), which allow the inner ear to be accessed directly through the external auditory canal (EAC), either with a microscopic (Expanded TTA, or ExpTTA) or even an exclusive endoscopic technique (Endoscopic TTA, or EndoTTA)...
June 9, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28590839/contractility-differential-tension-and-membrane-removal-lead-zebrafish-epiboly-biomechanics
#12
Maria Marsal, Amayra Hernández-Vega, Enrique Martin-Blanco
Precise tissue remodeling during development is essential for shaping embryos and optimal organ function. Epiboly is an early gastrulation event by which the blastoderm expands around the yolk to engulf it. Three different layers are involved in this process, an epithelial layer (the enveloping layer, EVL), the embryo proper, constituted by the deep cells (DCs), and the yolk cell. Although teleost epiboly has been studied for many years, a clear understanding of its mechanics was still missing. Here we present new information on the cellular, molecular and mechanical elements involved in epiboly that, together with some other recent data and upon comparison with previous biomechanical models, lets conclude that the expansion of the epithelia is passive and driven by active cortical contraction and membrane removal in the adjacent layer, the External Yolk Syncytial Layer (E-YSL)...
July 18, 2017: Cell Cycle
https://www.readbyqxmd.com/read/28539245/external-validation-of-the-breast-reconstruction-risk-assessment-calculator
#13
Nima Khavanin, Cecil S Qiu, Alexei S Mlodinow, Michael M Vu, Robert G Dorfman, Neil A Fine, John Y S Kim
INTRODUCTION: The Breast reconstruction Risk Assessment (BRA) Score estimates patient-specific risk for postsurgical complications using an individual's unique combination of preoperative variables. In this report, we externally validate the BRA Score models for surgical site infection, seroma, and explantation in a large sample of intra-institutional patients who underwent prosthetic breast reconstruction. METHODS: We reviewed all initiated tissue expander/implant reconstructions by the senior authors from January 2004 to December 2015...
July 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28445373/auricular-reconstruction-in-hemifacial-microsomia-with-an-expanded-two-flap-method
#14
Jin Qian, Zhibin Li, Tun Liu, Xu Zhou, Qingguo Zhang
BACKGROUND: Reconstruction of external ear is important for the child/adult with craniofacial deformities to achieve balance and harmony of the face and head. The aim of this study was to investigate the clinical application of an expanded two-flap method for auricular reconstruction in hemifacial microsomia. METHODS: Between January of 2014 and November of 2015, 111 hemifacial microsomia patients with microtia underwent auricular reconstruction with an expanded two-flap method...
May 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28379940/the-crown-of-thorns-starfish-genome-as-a-guide-for-biocontrol-of-this-coral-reef-pest
#15
Michael R Hall, Kevin M Kocot, Kenneth W Baughman, Selene L Fernandez-Valverde, Marie E A Gauthier, William L Hatleberg, Arunkumar Krishnan, Carmel McDougall, Cherie A Motti, Eiichi Shoguchi, Tianfang Wang, Xueyan Xiang, Min Zhao, Utpal Bose, Chuya Shinzato, Kanako Hisata, Manabu Fujie, Miyuki Kanda, Scott F Cummins, Noriyuki Satoh, Sandie M Degnan, Bernard M Degnan
The crown-of-thorns starfish (COTS, the Acanthaster planci species group) is a highly fecund predator of reef-building corals throughout the Indo-Pacific region. COTS population outbreaks cause substantial loss of coral cover, diminishing the integrity and resilience of reef ecosystems. Here we sequenced genomes of COTS from the Great Barrier Reef, Australia and Okinawa, Japan to identify gene products that underlie species-specific communication and could potentially be used in biocontrol strategies. We focused on water-borne chemical plumes released from aggregating COTS, which make the normally sedentary starfish become highly active...
April 5, 2017: Nature
https://www.readbyqxmd.com/read/28356202/role-of-tissue-expansion-in-abdominal-wall-reconstruction-a-systematic-evidence-based-review
#16
REVIEW
Kimberly E Wooten, Cemile Nurdan Ozturk, Can Ozturk, Peter Laub, Nell Aronoff, Raffi Gurunluoglu
BACKGROUND: Tissue expanders (TEs) can be used to assist primary closure of complicated hernias and large abdominal wall defects. However, there is no consensus regarding the optimal technique, use, or associated risk of TE in abdominal wall reconstruction. METHODS: A systematic search of PubMed and Embase databases was conducted to identify articles reporting abdominal wall reconstruction with TE techniques. English articles published between 1980 and 2016 were included on the basis of the following inclusion criteria: two-stage TE surgical technique, >3 cases, reporting of postoperative complications, hernia recurrence, and patient-based clinical data...
June 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28355119/high-intensity-focused-ultrasound-for-the-treatment-of-prostate-cancer-a-review
#17
REVIEW
Christian G Chaussy, Stefan Thüroff
Over the past 25 years, the average life expectancy for men has increased almost 4 years, and the age of prostate cancer detection has decreased an average of 10 years with diagnosis increasingly made at early-stage disease where curative therapy is possible. These changing trends in the age and extent of malignancy at diagnosis have revealed limitations in conventional curative therapies for prostate cancer, including a significant risk of aggressive cancer recurrence, and the risk of long-term genitourinary morbidity and its detrimental impact on patient's quality of life (QOL)...
April 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28350665/moderate-intensity-intermittent-external-volume-expansion-optimizes-the-soft-tissue-response-in-a-murine-model
#18
Giorgio Giatsidis, Liying Cheng, Federico Facchin, Anthony Haddad, Jorge Lujan-Hernandez, Luca Lancerotto, Christoph Gunther Nabzdyk, Hajime Matsumine, Dennis P Orgill
BACKGROUND: Intermittent external volume expansion using suction enhances the vascular network of soft tissues, possibly increasing fat graft survival. However, the optimal kinetics of application have not been determined. Based on their previous experience, the authors hypothesized that moderate-intensity intermittent external volume expansion application may further enhance both the angiogenic and adipogenic potential. METHODS: Fifty 12-week-old wild-type mice were assigned to five experimental groups (n = 10 per group) and underwent five different intermittent applications of external volume expansion (i...
April 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28202576/differential-effect-of-brief-electrical-stimulation-on-voltage-gated-potassium-channels
#19
Morven A Cameron, Amr Al Abed, Yossi Buskila, Socrates Dokos, Nigel H Lovell, John W Morley
Electrical stimulation of neuronal tissue is a promising strategy to treat a variety of neurological disorders. The mechanism of neuronal activation by external electrical stimulation is governed by voltage-gated ion channels. This stimulus, typically brief in nature, leads to membrane potential depolarization, which increases ion flow across the membrane by increasing the open probability of these voltage-gated channels. In spiking neurons, it is activation of voltage-gated sodium channels (NaV channels) that leads to action potential generation...
May 1, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28141644/midfacial-changes-through-anterior-maxillary-distraction-osteogenesis-in-patients-with-cleft-lip-and-palate
#20
Hiroyuki Kanzaki, Yoshimichi Imai, Tetsu Nakajo, Takayoshi Daimaruya, Akimitsu Sato, Masahiro Tachi, Youhei Nunomura, Yusuke Itagaki, Kazuaki Nishimura, Shoko Kochi, Kaoru Igarashi
Maxillary hypoplasia is a major issue in cleft lip and palate patients, and predictable surgical maxillary advancement is required. In the present study, the changes and stability of the maxilla and soft tissue profile achieved after the application of anterior maxillary distraction osteogenesis (AMDO) using intraoral expander in unilateral cleft lip and palate and isolated cleft palate patients were investigated by comparing to the Le Fort I osteotomy (LFI) and maxillary distraction osteogenesis (DO) with rigid external distraction (RED) system...
June 2017: Journal of Craniofacial Surgery
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